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Fakultät Biologie, ZMB, Chemische Biologie
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Universitätsstr 2
45117 Essen
45117 Essen
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S03 S02 A55
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Professor/in, Chemische Biologie
Aktuelle Veranstaltungen
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2024 WS
- Einführung in die Biochemie
- Molekulare Mikrobiologie und chemische Biologie (5.Sem. MedBio/Bio)
- Einführung in die Medizinische Biologie
- Übung zur Biochemie
- Chemische Biologie für Molekularbiologen
- Allgemeine Methoden (Bachelor Bio)
- Praktikum molekulare Mikrobiologie und chemische Biologie (MedBio/Bio)
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
Vergangene Veranstaltungen (max. 10)
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2024 SS
- Molekularbiologie und Biochemie
- Biochemie für Molekularbiologen
- Bioorganik
- Praktikum Chemie für Lehramtsstudierende
- Vorlesung Chemie für Lehramtsstudierende
- Praktikum zur Biochemie für Molekularbiologen
- Mikro- und Zell- und chemische Biologie
- Chemie für Biologen
- ZJA40170 Biochemie
- ZJA92071 Mikro-, Zell- und Chemische Biologie
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathwayIn: Nature Nanotechnology (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant–pathogen interfaceIn: New Phytologist Jg. 241 (2024) Nr. 1, S. 394 - 408Online Volltext: dx.doi.org/ (Open Access)
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Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor productionIn: Chem (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Characterization of 2-phenanthroate : CoA ligase from the sulfate-reducing, phenanthrene-degrading enrichment culture TRIPIn: Applied and Environmental Microbiology (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Differences in the Synovial Fluid Proteome of Septic and Aseptic Implant FailureIn: Antibiotics Jg. 13 (2024) Nr. 4, 346Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Discovery of active mouse, plant and fungal cytochrome P450s in endogenous proteomes and upon expression in plantaIn: Scientific Reports Jg. 14 (2024) Nr. 1, 10091Online Volltext: dx.doi.org/ (Open Access)
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Environmental activity-based protein profiling for function-driven enzyme discovery from natural communitiesIn: Environmental Microbiomes Jg. 19 (2024) Nr. 1, 36Online Volltext: dx.doi.org/ (Open Access)
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Factors governing attachment of Rhizobium leguminosarum to legume roots at acid, neutral, and alkaline pHsIn: mSystems Jg. 9 (2024) Nr. 9, e0042224Online Volltext: dx.doi.org/ (Open Access)
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Glutathione Transferase Photoaffinity Labeling Displays GST Induction by Safeners and Pathogen InfectionIn: Plant and Cell Physiology Jg. 65 (2024) Nr. 1, S. 128 - 141Online Volltext: dx.doi.org/ (Open Access)
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Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptorIn: Current Biology Jg. 34 (2024) Nr. 11, S. 2279 - 2293.e6Online Volltext: dx.doi.org/ (Open Access)
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Rational correction of pathogenic conformational defects in HTRA1In: Nature Communications Jg. 15 (2024) Nr. 1, 5944Online Volltext: dx.doi.org/ (Open Access)
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The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113In: Cell Chemical Biology (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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The proteome of Nicotiana benthamiana is shaped by extensive protein processingIn: New Phytologist Jg. 243 (2024) Nr. 3, S. 1034 - 1049Online Volltext: dx.doi.org/ (Open Access)
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TopBP1 utilises a bipartite GINS binding mode to support genome replicationIn: Nature Communications Jg. 15 (2024) Nr. 1, 1797Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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10q26 – The enigma in age-related macular degenerationIn: Progress in Retinal and Eye Research Jg. 96 (2023) 101154Online Volltext: dx.doi.org/ (Open Access)
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Chemoproteomics Reveals the Pan-HER Kinase Inhibitor Neratinib To Target an Arabidopsis Epoxide Hydrolase Related to Phytohormone SignalingIn: ACS Chemical Biology Jg. 18 (2023) Nr. 5, S. 1076 - 1088Online Volltext: dx.doi.org/
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Clp-targeting BacPROTACs impair mycobacterial proteostasis and survivalIn: Cell Jg. 186 (2023) Nr. 10, S. 2176 - 2192.e22Online Volltext: dx.doi.org/ (Open Access)
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Enhanced late blight resistance by engineering an EpiC2B-insensitive immune proteaseIn: Plant Biotechnology Journal Jg. 22 (2023) Nr. 2, S. 284 - 286Online Volltext: dx.doi.org/ (Open Access)
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Facile Multicomponent Synthesis of Oxazolidinones from Primary Amines and Cesium (Hydrogen)CarbonateIn: European Journal of Organic Chemistry Jg. 26 (2023) Nr. 27, e202300135Online Volltext: dx.doi.org/ (Open Access)
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IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilizationIn: Cell Chemical Biology Jg. 30 (2023) Nr. 6, S. 573 - 590.e6Online Volltext: dx.doi.org/
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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications Jg. 14 (2023) Nr. 1, 3258Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The root pathogen Aphanomyces euteiches secretes modular proteases in pea apoplast during host infectionIn: Frontiers in Plant Science (FPLS) Jg. 14 (2023) 1140101Online Volltext: dx.doi.org/ (Open Access)
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Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1EIn: Frontiers in Microbiology Jg. 12 (2022) 734039Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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BacPROTACs mediate targeted protein degradation in bacteriaIn: Cell Jg. 185 (2022) Nr. 13, S. 2338 - 2353.e18Online Volltext: dx.doi.org/ (Open Access)
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Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9In: Angewandte Chemie International Edition Jg. 61 (2022) Nr. 47, e202210498Online Volltext: dx.doi.org/ (Open Access)
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Erratum: Author Correction: Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling (Communications biology (2022) 5 1 (1254))In: Communications Biology Jg. 5 (2022) Nr. 1, S. 1319Online Volltext: dx.doi.org/ (Open Access)
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Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profilingIn: Communications Biology Jg. 5 (2022) Nr. 1, 1254Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Persister state-directed transitioning and vulnerability in melanomaIn: Nature Communications Jg. 13 (2022) Nr. 1, 3055Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Article leaf apoplast of field-grown potato analyzed by quantitative proteomics and activity-based protein profilingIn: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 21, 12033Online Volltext: dx.doi.org/ (Open Access)
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Correction to : Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteriaIn: Applied Microbiology and Biotechnology Jg. 105 (2021) Nr. 14-15, S. 6119 - 6119Online Volltext: dx.doi.org/ (Open Access)
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports Jg. 37 (2021) Nr. 8, 110056Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Targeted substrate loop insertion by VCP/p97 during PP1 complex disassemblyIn: Nature Structural & Molecular Biology Jg. 28 (2021) Nr. 12, S. 964 - 971Online Volltext: dx.doi.org/
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The chemical compound ‘Heatin’ stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilasesIn: The Plant Journal Jg. 106 (2021) Nr. 6, S. 1523 - 1540Online Volltext: dx.doi.org/ (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719Online Volltext: dx.doi.org/ (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719Online Volltext: dx.doi.org/ (Open Access)
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Activation by substoichiometric inhibitionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 117 (2020) Nr. 3, S. 1414 - 1418Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture methodIn: Biomolecules Jg. 10 (2020) Nr. 4, 661Online Volltext: dx.doi.org/ (Open Access)
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From dolastatin 13 to cyanopeptolins, micropeptins, and lyngbyastatins : the chemical biology of Ahp-cyclodepsipeptidesIn: Natural Product Reports Jg. 37 (2020) Nr. 2, S. 163 - 174Online Volltext: dx.doi.org/
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Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteriaIn: Applied Microbiology and Biotechnology Jg. 104 (2020) Nr. 13, S. 5985 - 5998Online Volltext: dx.doi.org/ (Open Access)
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Protein Phosphatase-1 Complex Disassembly by p97 is Initiated through Multivalent Recognition of Catalytic and Regulatory Subunits by the p97 SEP-domain AdaptersIn: Journal of Molecular Biology (JMB) Jg. 432 (2020) Nr. 23, S. 6061 - 6074Online Volltext: dx.doi.org/
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Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactionsIn: Nature Communications Jg. 11 (2020) Nr. 1, S. 3954Online Volltext: dx.doi.org/ (Open Access)
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Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry Jg. 401 (2020) Nr. 8, S. 955 - 968Online Volltext: dx.doi.org/ (Open Access)
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Using proteomics for an insight into the performance of activated sludge in a lab-scale WWTPIn: International Biodeterioration & Biodegradation Jg. 149 (2020) S. 104934Online Volltext: dx.doi.org/
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Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product FamilyIn: Chemistry - A European Journal Jg. 26 (2020) Nr. 39, S. 8524 - 8531Online Volltext: dx.doi.org/ (Open Access)
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A homology-guided, genome-based proteome for improved proteomics in the alloploid Nicotiana benthamianaIn: BMC Genomics Jg. 20 (2019) Nr. 1, S. 722Online Volltext: dx.doi.org/ (Open Access)
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Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor S/CYS8 in Nicotiana benthamianaIn: Plant Biotechnology Journal Jg. 17 (2019) Nr. 8, S. 1670 - 1678Online Volltext: dx.doi.org/ (Open Access)
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Cathepsin L regulates metabolic networks controlling rapid cell growth and proliferationIn: Molecular and Cellular Proteomics (MCP) Jg. 18 (2019) Nr. 7, S. 1330 - 1344Online Volltext: dx.doi.org/ (Open Access)
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Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam CellsIn: Cellular Physiology and Biochemistry Jg. 53 (2019) Nr. 3, S. 550 - 572Online Volltext: dx.doi.org/ (Open Access)
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Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of ActionIn: ChemMedChem Jg. 14 (2019) Nr. 11, S. 1074 - 1078Online Volltext: dx.doi.org/
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Dynamic hydrolase labelling as a marker for seed quality in Arabidopsis seedsIn: Biochemical Journal Jg. 476 (2019) Nr. 5, S. 843 - 857Online Volltext: dx.doi.org/ (Open Access)
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Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptidesIn: Science Jg. 364 (2019) Nr. 6436, eaav0748Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Metabolic reconstruction of the genome of candidate Desulfatiglans TRIP_1 and identification of key candidate enzymes for anaerobic phenanthrene degradationIn: Environmental Microbiology Jg. 21 (2019) Nr. 4, S. 1267 - 1286Online Volltext: dx.doi.org/ (Open Access)
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Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathwayIn: Scientific Reports Jg. 9 (2019) Nr. 1, S. 11196Online Volltext: dx.doi.org/ (Open Access)
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Proteases underground : Analysis of the maize root apoplast identifies organ specific papain-like cysteine protease activityIn: Frontiers in Plant Science (FPLS) Jg. 10 (2019)Online Volltext: dx.doi.org/ (Open Access)
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Triazine probes target ascorbate peroxidases in plantsIn: Plant Physiology Jg. 180 (2019) Nr. 4, S. 1848 - 1859Online Volltext: dx.doi.org/ (Open Access)
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A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPasesIn: Angewandte Chemie International Edition Jg. 57 (2018) Nr. 6, S. 1576 - 1580Online Volltext: dx.doi.org/
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An apoplastic peptide activates salicylic acid signalling in maizeIn: Nature Plants Jg. 4 (2018) Nr. 3, S. 172 - 180Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitatsIn: ISME Journal Jg. 12 (2018) Nr. 8, S. 2039 - 2050Online Volltext: dx.doi.org/ (Open Access)
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HTRA1-Dependent Cell Cycle ProteomicsIn: Journal of Proteome Research Jg. 17 (2018) Nr. 8, S. 2679 - 2694Online Volltext: dx.doi.org/
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Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent ProbesIn: ACS Chemical Biology Jg. 13 (2018) Nr. 5, S. 1307 - 1312Online Volltext: dx.doi.org/
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Identification of the Natural Product RotihibinA as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional ProfilingIn: Chemistry - A European Journal Jg. 24 (2018) Nr. 48, S. 12500 - 12504Online Volltext: dx.doi.org/
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Low Protease Content in Medicago truncatula Cell Cultures Facilitates Recombinant Protein ProductionIn: Biotechnology Journal Jg. 13 (2018) Nr. 7, 1800050Online Volltext: dx.doi.org/
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Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular “Lysine Wrapping” of Oligoethylene Glycol (OEG) Moieties in ProteinsIn: Chemistry - A European Journal (2018)Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in PlantsIn: Plant Physiology Jg. 177 (2018) Nr. 1, S. 24 - 37Online Volltext: dx.doi.org/ (Open Access)
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Protease Activities Triggered by Ralstonia solanacearum Infection in Susceptible and Tolerant Tomato LinesIn: Molecular and Cellular Proteomics (MCP) Jg. 17 (2018) Nr. 6, S. 1112 - 1125Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The transcriptome, extracellular proteome and active secretome of agroinfiltrated Nicotiana benthamiana uncover a large, diverse protease repertoireIn: Plant Biotechnology Journal Jg. 16 (2018) Nr. 5, S. 1068 - 1084Online Volltext: dx.doi.org/ (Open Access)
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Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamianaIn: Plant Biotechnology Journal Jg. 16 (2018) Nr. 10, S. 1797 - 1810Online Volltext: dx.doi.org/ (Open Access)
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Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme FormationIn: Molecular Cell Jg. 72 (2018) Nr. 4, S. 766 - 777Online Volltext: dx.doi.org/ (Open Access)
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Utilities for Mass Spectrometry Analysis of Proteins (UMSAP) : Fast post-processing of mass spectrometry dataIn: Rapid Communications in Mass Spectrometry Jg. 32 (2018) Nr. 19, S. 1659 - 1667Online Volltext: dx.doi.org/
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Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic ArchaeaIn: Nature Communications Jg. 8 (2017) S. 15352Online Volltext: dx.doi.org/ (Open Access)
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Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expressionIn: Antioxidants and Redox Signaling Jg. 26 (2017) Nr. 11, S. 563 - 582Online Volltext: dx.doi.org/ (Open Access)
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Proteasome activity profiling uncovers alteration of catalytic β2 and β5 subunits of the stress-induced proteasome during salinity stress in tomato rootsIn: Frontiers in Plant Science (FPLS) Jg. 8 (2017) 107Online Volltext: dx.doi.org/ (Open Access)
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Quantitative proteomics reveals ecophysiological effects of light and silver stress on the mixotrophic protist Poterioochromonas malhamensisIn: PLoS ONE Jg. 12 (2017) Nr. 1, S. e0168183Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Small Molecules from Deep within the GutIn: ChemBioChem Jg. 18 (2017) Nr. 11, S. 967 - 968Online Volltext: dx.doi.org/
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Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infectionsIn: The Plant Journal Jg. 90 (2017) Nr. 2, S. 418 - 430Online Volltext: dx.doi.org/
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Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease InhibitorsIn: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 29, Special Issue: 100th Anniversary of the Royal Australian Chemical Institute, S. 8555 - 8558Online Volltext: dx.doi.org/
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The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian ClockIn: ACS Chemical Biology Jg. 12 (2017) Nr. 6, S. 1466 - 1471Online Volltext: dx.doi.org/ (Open Access)
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Turning-ON ProteasomesIn: Cell Chemical Biology Jg. 24 (2017) Nr. 6, S. 653 - 655Online Volltext: dx.doi.org/
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A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosisIn: Chemical Science Jg. 7 (2016) S. 1322 - 1337Online Volltext: dx.doi.org/ (Open Access)
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Capture of endogenously biotinylated proteins from Pseudomonas aeruginosa displays unexpected downregulation of LiuD upon iron nutritionIn: Bioorganic and Medicinal Chemistry Jg. 24 (2016) Nr. 15, S. 3330 - 3335Online Volltext: dx.doi.org/
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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break RepairIn: Molecular Cell Jg. 64 (2016) Nr. 1, S. 189 - 198Online Volltext: dx.doi.org/ (Open Access)
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Chemical proteomics versus LeishmaniasisIn: Chemistry and Biology Jg. 22 (2015) Nr. 3, S. 309 - 310Online Volltext: dx.doi.org/ (Open Access)
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Chemoproteomic Evaluation of the Polyacetylene Callyspongynic AcidIn: Chemistry - A European Journal Jg. 21 (2015) Nr. 30, S. 10721 - 10728Online Volltext: dx.doi.org/ (Open Access)
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Determinants of amyloid fibril degradation by the PDZ protease HTRA1In: Nature Chemical Biology Jg. 11 (2015) Nr. 11, S. 862 - 869Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Functional divergence of two secreted immune proteases of tomatoIn: Current Biology Jg. 25 (2015) Nr. 17, S. 2300 - 2306Online Volltext: dx.doi.org/ (Open Access)
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Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERTIn: Nucleic Acids Research Jg. 43 (2015) Nr. 15, art. no. e99Online Volltext: dx.doi.org/ (Open Access)
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Subfamily-specific fluorescent probes for cysteine proteases display dynamic protease activities during seed germinationIn: Plant Physiology Jg. 168 (2015) Nr. 4, S. 1462 - 1475Online Volltext: dx.doi.org/
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Synthesis of a hexahydropyrrolo indole (HPI) compound libraryIn: Bioorganic and Medicinal Chemistry Jg. 23 (2015) Nr. 11, S. 2636 - 2645Online Volltext: dx.doi.org/
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A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thalianaIn: Nature Chemical Biology Jg. 10 (2014) Nr. 10, S. 830 - 836Online Volltext: dx.doi.org/
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Building up a chemical proteomics network in Europe and beyondIn: ACS Chemical Biology Jg. 9 (2014) Nr. 8, S. 1647 - 1648Online Volltext: dx.doi.org/
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Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Jg. 15 (2014) Nr. 15, S. 2233 - 2237Online Volltext: dx.doi.org/
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Synthesis of the B-seco limonoid core scaffoldIn: Beilstein Journal of Organic Chemistry Jg. 10 (2014) S. 194 - 208Online Volltext: dx.doi.org/ (Open Access)
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A substrate-inspired probe monitors translocation, activation, and subcellular targeting of bacterial type III effector protease AvrPphBIn: Chemistry and Biology Jg. 20 (2013) Nr. 2, S. 168 - 176Online Volltext: dx.doi.org/
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Ahp cyclodepsipeptides: The impact of the ahp residue on the "Canonical Inhibition" of S1 serine proteasesIn: ChemBioChem Jg. 14 (2013) Nr. 11, S. 1301 - 1308Online Volltext: dx.doi.org/
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Case studies of the synthesis of bioactive cyclodepsipeptide natural productsIn: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Jg. 18 (2013) Nr. 2, S. 1337 - 1367Online Volltext: dx.doi.org/ (Open Access)
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Chemical proteomics with sulfonyl fluoride probes reveals selective labeling of functional tyrosines in glutathione transferasesIn: Chemistry and Biology Jg. 20 (2013) Nr. 4, S. 541 - 548Online Volltext: dx.doi.org/ (Open Access)
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Diversity of allosteric regulation in proteasesIn: ACS Chemical Biology Jg. 8 (2013) Nr. 1, S. 19 - 26Online Volltext: dx.doi.org/
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Profiling protein kinases and other ATP binding proteins in arabidopsis using acyl-ATP probesIn: Molecular and Cellular Proteomics (MCP) Jg. 12 (2013) Nr. 9, S. 2481 - 2496Online Volltext: dx.doi.org/
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Pseudomonas syringae pv. syringae Uses Proteasome Inhibitor Syringolin A to Colonize from Wound Infection SitesIn: PLoS Pathogens Jg. 9 (2013) Nr. 3, S. e1003281Online Volltext: dx.doi.org/ (Open Access)
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Streamlining chemical probe discovery : libraries of "fully functionalized" small molecules for phenotypic screeningIn: Angewandte Chemie International Edition Jg. 52 (2013) Nr. 5, S. 1368 - 1370Online Volltext: dx.doi.org/
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A para-nitrophenol phosphonate probe labels distinct serine hydrolases of ArabidopsisIn: Bioorganic and Medicinal Chemistry Jg. 20 (2012) Nr. 2, S. 601 - 606Online Volltext: dx.doi.org/
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Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cellsIn: Biochemistry Jg. 51 (2012) Nr. 34, S. 6880 - 6888Online Volltext: dx.doi.org/
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Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivoIn: The FASEB Journal Jg. 26 (2012) Nr. 8, S. 3421 - 3429Online Volltext: dx.doi.org/
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Challenges in the syntheses of peptidic natural productsIn: Synthesis: Journal of Synthetic Organic Chemistry Jg. 44 (2012) Nr. 12, S. 1755 - 1777Online Volltext: dx.doi.org/
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Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ ProteaseIn: ChemBioChem Jg. 13 (2012) Nr. 3, S. 402 - 408Online Volltext: dx.doi.org/
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Development of a Solid-Phase Approach to the Natural Product Class of Ahp-Containing CyclodepsipeptidesIn: European Journal of Organic Chemistry (2012) Nr. 8, S. 1616 - 1625Online Volltext: dx.doi.org/
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Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketonesIn: Organic and Biomolecular Chemistry Jg. 10 (2012) Nr. 1, S. 181 - 194Online Volltext: dx.doi.org/
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E. coli LoiP (YggG), a metalloprotease hydrolyzing Phe–Phe bondsIn: Molecular BioSystems Jg. 8 (2012) Nr. 6, S. 1775 - 1782Online Volltext: dx.doi.org/ Online Volltext
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Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregatesIn: The Journal of Biological Chemistry (JBC) Jg. 287 (2012) Nr. 25, S. 20931 - 20941Online Volltext: dx.doi.org/
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Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenasesIn: Angewandte Chemie International Edition Jg. 51 (2012) Nr. 21, S. 5230 - 5233Online Volltext: dx.doi.org/
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In Silico Identification of an Interferon InhibitorIn: ChemMedChem Jg. 7 (2012) Nr. 4, S. 555 - 557Online Volltext: dx.doi.org/
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One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitorIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 109 (2012) Nr. 45, S. 18367 - 18371Online Volltext: dx.doi.org/
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Probes for activity-based profiling of plant proteasesIn: Physiologia Plantarum Jg. 145 (2012) Nr. 1, Special Issue: Plant Proteases, S. 18 - 27Online Volltext: dx.doi.org/
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Selective inhibition of plant serine hydrolases by agrochemicals revealed by competitive ABPPIn: Bioorganic and Medicinal Chemistry Jg. 20 (2012) Nr. 2, S. 597 - 600Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Small-molecule stabilization of protein-protein interactions : An underestimated concept in drug discovery?In: Angewandte Chemie International Edition Jg. 51 (2012) Nr. 9, S. 2012 - 2018Online Volltext: dx.doi.org/
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Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine ProteasesIn: ChemBioChem Jg. 13 (2012) Nr. 16, S. 2327 - 2330Online Volltext: dx.doi.org/
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The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipainsIn: Chemistry and Biology Jg. 19 (2012) Nr. 12, S. 1546 - 1555Online Volltext: dx.doi.org/
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The impact of plant-pathogen studies on medicinal drug discoveryIn: Chemical Society Reviews Jg. 41 (2012) Nr. 8, S. 3168 - 3178Online Volltext: dx.doi.org/
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Enzymatic timing and tailoring of macrolactamization in syringolin biosynthesisIn: Organic Letters Jg. 13 (2011) Nr. 17, S. 4518 - 4521Online Volltext: dx.doi.org/
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HTRA proteases : regulated proteolysis in protein quality controlIn: Nature Reviews Molecular Cell Biology Jg. 12 (2011) Nr. 3, S. 152 - 162Online Volltext: dx.doi.org/
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Macrocyclic Proteasome InhibitorsIn: Current Medicinal Chemistry Jg. 18 (2011) Nr. 33, S. 5052 - 5060Online Volltext: dx.doi.org/
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A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-PyronesIn: Angewandte Chemie International Edition Jg. 49 (2010) Nr. 21, S. 3666 - 3670Online Volltext: dx.doi.org/
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Biology-Oriented Combined Solid- and Solution-Phase Synthesis of a Macroline-Like Compound CollectionIn: Chemistry - A European Journal Jg. 15 (2009) Nr. 44, S. 11976 - 11984Online Volltext: dx.doi.org/
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Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using ‘click chemistry’.In: The Plant Journal Jg. 57 (2009) Nr. 2, S. 373 - 385
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Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 106 (2009) Nr. 40, S. 17223 - 17228Online Volltext: dx.doi.org/
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Syringolin A selectively labels the 20S proteasome in murine EL4 and wildtype and bortezomib adapted leukemic cell linesIn: ChemBioChem Jg. 10 (2009) Nr. 16, S. 2638 - 2643Online Volltext: dx.doi.org/ Online Volltext
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Editorial : When chemistry meets biology – Generating innovative concepts, methods and tools for scientific discovery in the plant sciencesIn: Frontiers in Plant Science (FPLS) Jg. 7 (2016) Nr. February, 76Online Volltext: dx.doi.org/ (Open Access)
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