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Dr. rer. nat Christopher Bräsen

Raum
S05 V03 F38
Telefon
+49 201 183 7063
E-Mail
christopher.braesen@uni-due.de

Funktionen

  • Wissenschaftliche/r Mitarbeiter/in, Prof. Siebers

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Schmerling, Christian; Schroeder, Carsten; Zhou, Xiaoxiao; Bost, Jan; Waßmer, Bianca; Ninck, Sabrina; Busche, Tobias; Montero, Lidia; Kaschani, Farnusch; Schmitz, Oliver J.; Kalinowski, Jörn; Kaiser, Markus; Albers, Sonja-Verena; Bräsen, Christopher; Siebers, Bettina
    An unusual glycerol-3-phosphate dehydrogenase in Sulfolobus acidocaldarius elucidates the diversity of glycerol metabolism across Archaea
    In: Communications Biology, Jg. 8, 2025, Nr. 1, 539
    DOI (Open Access)
  • Stracke, Christina; Meyer, Benjamin H.; De Rose, Simone A.; Ferrandi, Erica Elisa; Kublanov, Ilya V.; Isupov, Michail N.; Harmer, Nicholas J.; Monti, Daniela; Littlechild, Jennifer; Müller, Felix; Snoep, Jacky L.; Bräsen, Christopher; Siebers, Bettina
    Establishment of an efficient one-step enzymatic synthesis of cyclic-2,3-diphosphoglycerate
    In: Frontiers in Microbiology, Jg. 16, 2025, 1601972
    DOI, Online Volltext (Open Access)
  • Caliebe, Frauke; Ojha, Ravi Shankar; Gruber, Marco; Boehm, Marko; Shen, Lu; Bräsen, Christopher; Snoep, Jacky L; Forchhammer, Karl; Hagemann, Martin; Siebers, Bettina; Gutekunst, Kirstin
    Fructose-1,6-bisphosphatase is involved in heterotrophic growth and glycogen metabolism in cyanobacteria
    In: Journal of Experimental Botany (JEB), 2025, in press
    DOI (Open Access)
  • Kuschmierz, Laura; Wagner, Alexander; Schmerling, Christian; Busche, Tobias; Kalinowski, Jörn; Bräsen, Christopher; Siebers, Bettina
    5′-untranslated region sequences enhance plasmid-based protein production in Sulfolobus acidocaldarius
    In: Frontiers in Microbiology, Jg. 15, 2024, 1443342
    DOI, Online Volltext (Open Access)
  • Ninck, Sabrina; Klaus, Thomas; Kochetkova, Tatiana V.; Esser, Sarah P.; Sewald, Leonard; Kaschani, Farnusch; Bräsen, Christopher; Probst, Alexander J.; Kublanov, Ilya V.; Siebers, Bettina; Kaiser, Markus
    Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities
    In: Environmental Microbiomes, Jg. 19, 2024, Nr. 1, 36
    DOI, Online Volltext (Open Access)
  • Shen, Lu; Peraglie, Carmen; Podlesainski, David; Stracke, Christina; Ojha, Ravi Shankar; Caliebe, Frauke; Kaiser, Markus; Forchhammer, Karl; Hagemann, Martin; Gutekunst, Kirstin; Snoep, Jacky L.; Bräsen, Christopher; Siebers, Bettina
    Structure function analysis of ADP-dependent cyanobacterial phosphofructokinase reveals new phylogenetic grouping in the PFK-A family
    In: The Journal of Biological Chemistry (JBC), Jg. 300, 2024, Nr. 11, 107868
    DOI, Online Volltext (Open Access)
  • Klaus, Thomas; Ninck, Sabrina; Albersmeier, Andreas; Busche, Tobias; Wibberg, Daniel; Jiang, Jianbing; Elcheninov, Alexander G.; Zayulina, Kseniya S.; Kaschani, Farnusch; Bräsen, Christopher; Overkleeft, Herman S.; Kalinowski, Jörn; Kublanov, Ilya V.; Kaiser, Markus; Siebers, Bettina
    Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1E
    In: Frontiers in Microbiology, Jg. 12, 2022, 734039
    DOI, Online Volltext (Open Access)
  • Schmerling, Christian; Kouril, Theresa; Snoep, Jacky; Bräsen, Christopher; Siebers, Bettina
    Enhanced underground metabolism challenges life at high temperature–metabolic thermoadaptation in hyperthermophilic Archaea
    In: Current Opinion in Systems Biology, Jg. 30, 2022, 100423
    DOI, Online Volltext (Open Access)
  • Schmerling, Christian; Sewald, Leonard; Heilmann, Geronimo; Witfeld, Frederick; Begerow, Dominik; Jensen, Kenneth; Bräsen, Christopher; Kaschani, Farnusch; Overkleeft, Herman S.; Siebers, Bettina; Kaiser, Markus
    Erratum: Author Correction: Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling (Communications biology (2022) 5 1 (1254))
    In: Communications Biology, Jg. 5, 2022, Nr. 1, S. 1319
    DOI (Open Access)
  • Kuschmierz, Laura; Meyer, Martin; Bräsen, Christopher; Wingender, Jost; Schmitz, Oliver J.; Siebers, Bettina
    Exopolysaccharide composition and size in Sulfolobus acidocaldarius biofilms
    In: Frontiers in Microbiology, Jg. 13, 2022, 982745
    DOI, Online Volltext (Open Access)
  • Schmerling, Christian; Sewald, Leonard; Heilmann, Geronimo; Witfeld, Frederick; Begerow, Dominik; Jensen, Kenneth; Bräsen, Christopher; Kaschani, Farnusch; Overkleeft, Herman S.; Siebers, Bettina; Kaiser, Markus
    Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
    In: Communications Biology, Jg. 5, 2022, Nr. 1, 1254
    DOI, Online Volltext (Open Access)
  • Kuschmierz, Laura; Shen, Lu; Bräsen, Christopher; Snoep, Jacky; Siebers, Bettina
    Workflows for optimization of enzyme cascades and whole cell catalysis based on enzyme kinetic characterization and pathway modelling
    In: Current Opinion in Biotechnology, Jg. 74, 2022, S. 55 – 60
    DOI, Online Volltext (Open Access)
  • Benninghoff, Jens C.; Kuschmierz, Laura; Zhou, Xiaoxiao; Albersmeier, Andreas; Pham, Trong Khoa; Busche, Tobias; Wright, Phillip C.; Kalinowski, Jörn; Makarova, Kira S.; Bräsen, Christopher; Flemming, Hans-Curt; Wingender, Jost; Siebers, Bettina
    Exposure to 1-Butanol Exemplifies the Response of the Thermoacidophilic Archaeon Sulfolobus acidocaldarius to Solvent Stress
    In: Applied and Environmental Microbiology, Jg. 87, 2021, Nr. 11
    DOI (Open Access)
  • Lewis, April M; Recalde, Alejandra; Bräsen, Christopher; Counts, James A; Nussbaum, Phillip; Bost, Jan; Schocke, Larissa; Shen, Lu; Willard, Daniel J; Quax, Tessa E. F; Peeters, Eveline; Siebers, Bettina; Albers, Sonja-Verena; Kelly, Robert M
    The biology of thermoacidophilic archaea from the order Sulfolobales
    In: FEMS Microbiology Reviews, Jg. 45, 2021, Nr. 4, fuaa063
    DOI, Online Volltext (Open Access)
  • Shen, Lu; Kohlhaas, Martha; Enoki, Junichi; Meier, Roland; Schönenberger, Bernhard; Wohlgemuth, Roland; Kourist, Robert; Niemeyer, Felix; van Niekerk, David; Bräsen, Christopher; Niemeyer, Jochen; Snoep, Jacky; Siebers, Bettina
    A combined experimental and modelling approach for the Weimberg pathway optimisation
    In: Nature Communications, Jg. 11, 2020, Nr. 1, S. 1098
    DOI (Open Access)
  • Krevet, Sabine; Shen, Lu; Bohnen, Timon; Schoenenberger, Bernhard; Meier, Roland; Obkircher, Markus; Bangert, Klara; Koehling, Rudolf; Allenspach, Eric; Wohlgemuth, Roland; Siebers, Bettina; Bräsen, Christopher
    Corrigendum: Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus (Frontiers in Bioengineering and Biotechnology, (2020), 8, 10.3389/fbioe.2020.00185)
    In: Frontiers in Bioengineering and Biotechnology, Jg. 8, 2020, S. 761
    DOI (Open Access)
  • Krevet, Sabine; Shen, Lu; Bohnen, Timon; Schoenenberger, Bernhard; Meier, Roland; Obkircher, Markus; Bangert, Klara; Koehling, Rudolf; Allenspach, Eric; Siebers, Bettina; Bräsen, Christopher
    Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus
    In: Frontiers in Bioengineering and Biotechnology, Jg. 8, 2020, S. 185
    DOI (Open Access)
  • Stracke, Christina; Meyer, Benjamin; Hagemann, Anna; Jo, Eunhye; Lee, Areum; Albers, Sonja-Verena; Cha, Jaeho; Bräsen, Christopher; Siebers, Bettina
    Salt Stress Response of Sulfolobus acidocaldarius Involves Complex Trehalose Metabolism Utilizing a Novel Trehalose-6-Phosphate Synthase (TPS)/Trehalose-6-Phosphate Phosphatase (TPP) Pathway
    In: Applied and Environmental Microbiology, Jg. 86, 2020, Nr. 24, S. e01565 – 20
    DOI (Open Access)
  • Wang, Kun; Sybers, David; Maklad, Hassan Ramadan; Lemmens, Liesbeth; Lewyllie, Charlotte; Zhou, Xiaoxiao; Schult, Frank; Bräsen, Christopher; Siebers, Bettina; Valegård, Karin; Lindås, Ann-Christin; Peeters, Eveline
    A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
    In: Nature Communications, Jg. 10, 2019, Nr. 1, S. 1542
    DOI (Open Access)
  • Haferkamp, Patrick; Tjaden, Britta; Shen, Lu; Bräsen, Christopher; Kouril, Theresa; Siebers, Bettina
    The Carbon Switch at the Level of Pyruvate and Phosphoenolpyruvate in Sulfolobus solfataricus P2
    In: Frontiers in Microbiology, Jg. 10, 2019, S. 757
    DOI, Online Volltext (Open Access)
  • Schocke, Larissa; Bräsen, Christopher; Siebers, Bettina
    Thermoacidophilic Sulfolobus species as source for extremozymes and as novel archaeal platform organisms
    In: Current Opinion in Biotechnology, Jg. 59, 2019, S. 71 – 77
    DOI
  • Wagner, Michaela; Shen, Lu; Albersmeier, Andreas; van der Kolk, Nienke; Kim, Sujin; Cha, Jaeho; Bräsen, Christopher; Kalinowski, Jörn; Siebers, Bettina; Albers, Sonja-Verena
    Sulfolobus acidocaldarius transports pentoses via a carbohydrate uptake transporter 2 (CUT2)-type ABC transporter and metabolizes them through the aldolase-independent Weimberg pathway
    In: Applied and Environmental Microbiology, Jg. 84, 2018, Nr. 3, S. e01273 – 17
    DOI (Open Access)
  • Zweerink, Susanne; Kallnik, Verena; Ninck, Sabrina; Nickel, Sabrina; Verheyen, Julia; Blum, Marcel; Wagner, Alexander; Feldmann, Ingo; Sickmann, Albert; Albers, Sonja-Verena; Bräsen, Christopher; Kaschani, Farnusch; Siebers, Bettina; Kaiser, Markus
    Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea
    In: Nature Communications, Jg. 8, 2017, S. 15352
    DOI (Open Access)
  • Wolf, Jacqueline; Stark, Helge; Fafenrot, Katharina; Albersmeier, Andreas; Pham, Trong K.; Müller, Katrin B.; Meyer, Benjamin H.; Hoffmann, Lena; Shen, Lu; Albaum, Stefan P.; Kouril, Theresa; Schmidt-Hohagen, Kerstin; Neumann-Schaal, Meina; Bräsen, Christopher; Kalinowski, Jörn; Wright, Phillip C.; Albers, Sonja-Verena; Schomburg, Dietmar; Siebers, Bettina
    A systems biology approach reveals major metabolic changes in the thermoacidophilic archaeon Sulfolobus solfataricus in response to the carbon source L-fucose versus D-glucose
    In: Molecular Microbiology, Jg. 102, 2016, Nr. 5, S. 882 – 908
    DOI (Open Access)
  • Gavrilov, Sergey N.; Stracke, Christina; Jensen, Kenneth; Menzel, Peter; Kallnik, Verena; Slesarev, Alexei; Sokolova, Tatyana; Zayulina, Kseniya; Bräsen, Christopher; Bonch-Osmolovskaya, Elizaveta A.; Peng, Xu; Kublanov, Ilya V.; Siebers, Bettina
    Isolation and Characterization of the First Xylanolytic Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1 and Its Unusual Multidomain Glycosidase
    In: Frontiers in Microbiology, Jg. 7, 2016, S. 00552
    DOI (Open Access)
  • Esser, Dominik; Hoffmann, Lena; Pham, Trong Khoa; Bräsen, Christopher; Qiu, Wen; Wright, Phillip C.; Albers, Sonja-Verena; Siebers, Bettina
    Protein phosphorylation and its role in archaeal signal transduction
    In: FEMS Microbiology Reviews, Jg. 40, 2016, Nr. 5, S. 625 – 647
    DOI (Open Access)
  • Jachlewski, Silke; Jachlewski, Witold D.; Linne, Uwe; Bräsen, Christopher; Wingender, Jost; Siebers, Bettina
    Isolation of Extracellular Polymeric Substances from Biofilms of the Thermoacidophilic Archaeon Sulfolobus acidocaldarius.
    In: Frontiers in Bioengineering and Biotechnology, Jg. 3, 2015, S. 123
    DOI, Online Volltext (Open Access)
  • Bräsen, Christopher; Esser, D.; Rauch, B.; Siebers, Bettina
    Carbohydrate metabolism in archaea : Current insights into unusual enzymes and pathways and their regulation
    In: JAMA Ophthalmology, Jg. 132, 2014, Nr. 3, S. 326 – 331
    DOI (Open Access)
  • Kallnik, Verena; Bunescu, Alina; Sayer, Christopher; Bräsen, Christopher; Wohlgemuth, Roland; Littlechild, Jennifer Ann; Siebers, Bettina
    Characterization of a phosphotriesterase-like lactonase from the hyperthermoacidophilic crenarchaeon Vulcanisaeta moutnovskia
    In: Journal of Biotechnology, 2014, Nr. 190, S. 11 – 17
    DOI
  • Matsubara, Kohei; Köhling, Rudi; Schönenberger, Bernhard; Kouril, Theresa; Esser, Dominik; Bräsen, Christopher; Siebers, Bettina; Wohlgemuth, Roland
    One-step synthesis of 2-keto-3-deoxy-D-gluconate by biocatalytic dehydration of D-gluconate
    In: Journal of Biotechnology, Jg. 191, 2014, S. 69 – 77
    DOI
  • Bräsen, Christopher; Siebers, Bettina
    Systembiologie X-trem : Von der Grundlagenforschung zur Anwendung in hyperthermophilen Archaea
    In: GIT: Labor-Fachzeitschrift, 2014, Nr. 12, S. 20 – 23
    Online Volltext
  • Zaparty, Melanie; Hagemann, Anna; Bräsen, Christopher; Hensel, Reinhard; Lupas, Andrei N.; Brinkmann, Henner; Siebers, Bettina
    The First Prokaryotic Trehalose Synthase Complex Identified in the Hyperthermophilic Crenarchaeon Thermoproteus tenax
    In: PLoS ONE, Jg. 8, 2013, Nr. 4, S. e61354
    DOI (Open Access)
  • Esser, Dominik; Kouril, Theresa; Talfournier, François; Polkowska, Jolanta; Schrader, Thomas; Bräsen, Christopher; Siebers, Bettina
    Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus
    In: Extremophiles, Jg. 17, 2013, Nr. 2, S. 205 – 216
    DOI

    • Preprints

  • Schmerling, Christian; Schroeder, Carsten; Zhou, Xiaoxiao; Busche, Tobias; Kalinowski, Jörn; Montero, Lidia; Schmitz, Oliver J.; Kaschani, Farnusch; Ninck, Sabrina; Kaiser, Markus; Bost, Jan; Waßmer, Bianca; Albers, Sonja; Siebers, Bettina; Bräsen, Christopher
    Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase
    2024
    DOI (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Höfmann, Svenja; Dziwornu, Promise Akua; Klaus, Thomas; Knura, Thomas; Wohlgemuth, Roland; Bräsen, Christopher; Siebers, Bettina
    Simplified Enzymatic Synthesis of 2-Keto-3-Deoxy-D-Gluconate from D-Gluconate Using the Gluconate Dehydratase from Thermoproteus tenax
    In: Archaea: Methods and Protocols / Ferreira-Cerca, Sébastien (Hrsg.). New York: Springer, 2022, S. 351 – 362
    DOI