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Leiter Abt. Translationale Onkologie m. Schwerpunkt Hautkrebsforschung, Klinik für Dermatologie
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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A Prospective Study Investigating Immune Checkpoint Molecule and CD39 Expression on Peripheral Blood Cells for the Prognostication of COVID-19 Severity and MortalityIn: Viruses Jg. 16 (2024) Nr. 5, 810Online Volltext: dx.doi.org/ (Open Access)
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Analyses of combined Merkel cell carcinomas with neuroblastic components suggests that loss of T antigen expression in Merkel cell carcinoma may result in cell cycle arrest and neuroblastic transdifferentiationIn: The Journal of Pathology Jg. 264 (2024) Nr. 1, S. 112 - 124Online Volltext: dx.doi.org/ (Open Access)
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Current Progress in Vaccines against Merkel Cell Carcinoma: A Narrative Review and UpdateIn: Vaccines Jg. 12 (2024) Nr. 5, 533Online Volltext: dx.doi.org/ (Open Access)
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Early versus late response to PD-1-based immunotherapy in metastatic melanomaIn: European Journal of Cancer (EJC) Jg. 210 (2024) 114295Online Volltext: dx.doi.org/ (Open Access)
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High intratumoral 5-hydroxymethylcytosine levels protect against disease relapse in patients with atypical fibroxanthoma and pleomorphic dermal sarcomaIn: British Journal of Dermatology: BJD Jg. 191 (2024) Nr. 2, S. 295 - 296Online Volltext: dx.doi.org/
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Incidence and Relative Survival of Patients with Merkel Cell Carcinoma in North Rhine-Westphalia, Germany, 2008–2021In: Cancers Jg. 16 (2024) Nr. 11, 2158Online Volltext: dx.doi.org/ (Open Access)
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Introducing MCC-PS : a novel prognostic score for Merkel cell carcinomaIn: Frontiers in Oncology Jg. 14 (2024) 1427740Online Volltext: dx.doi.org/ (Open Access)
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Merkel Cell Carcinoma : Integrating Epidemiology, Immunology, and Therapeutic UpdatesIn: American Journal of Clinical Dermatology Jg. 25 (2024) Nr. 4, S. 541 - 557Online Volltext: dx.doi.org/ (Open Access)
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Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1In: Journal of Medical Virology Jg. 96 (2024) Nr. 7, e29789Online Volltext: dx.doi.org/ (Open Access)
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Merkel-cell carcinoma : ESMO–EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-upIn: ESMO Open Jg. 9 (2024) Nr. 5, 102977Online Volltext: dx.doi.org/ (Open Access)
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Porocarcinomas with PAK1/2/3 fusions : a series of 12 casesIn: Histopathology Jg. 85 (2024) Nr. 4, S. 566 - 578Online Volltext: dx.doi.org/ (Open Access)
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S1-Guideline Sebaceous CarcinomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 22 (2024) Nr. 5, S. 730 - 747Online Volltext: dx.doi.org/ (Open Access)
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Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signatureIn: Frontiers in Oncology Jg. 14 (2024) 1408614Online Volltext: dx.doi.org/ (Open Access)
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T antigen–specific CD8⁺ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinomaIn: The Journal of Clinical Investigation (JCI) Jg. 134 (2024) Nr. 8, e177082Online Volltext: dx.doi.org/ (Open Access)
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The RANKL inhibitor denosumab in combination with dual checkpoint inhibition is associated with increased CXCL-13 serum concentrationsIn: European Journal of Cancer (EJC) Jg. 202 (2024) 113984Online Volltext: dx.doi.org/ (Open Access)
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Update Merkel-Zell-KarzinomIn: Die Onkologie (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Wnt/β-Catenin–Activated Nonpilomatrical Carcinoma of the Skin : A Case SeriesIn: Modern Pathology Jg. 37 (2024) Nr. 11, 100586Online Volltext: dx.doi.org/
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Adjuvant immunotherapy with nivolumab versus observation in completely resected Merkel cell carcinoma (ADMEC-O) : disease-free survival results from a randomised, open-label, phase 2 trialIn: Lancet Jg. 402 (2023) Nr. 10404, S. 798 - 808Online Volltext: dx.doi.org/
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B-cell lymphoma extra-large (Bcl-xL) is a promising drug target in Merkel cell carcinomaIn: British Journal of Dermatology: BJD (2023)Online Volltext: dx.doi.org/
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Brain metastasis and survival outcomes after first-line therapy in metastatic melanoma: a multicenter DeCOG study on 1704 patients from the prospective skin cancer registry ADOREGIn: Journal for ImmunoTherapy of Cancer Jg. 11 (2023) Nr. 4,Online Volltext: dx.doi.org/ (Open Access)
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COVID-19 vaccination in psoriasis patients receiving systemic treatment : A prospective single-center studyIn: Frontiers in Immunology Jg. 14 (2023) S. 1107438Online Volltext: dx.doi.org/ (Open Access)
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Characterisation and outcome of RAC1 mutated melanomaIn: European Journal of Cancer (EJC) Jg. 183 (2023) S. 1 - 10Online Volltext: dx.doi.org/
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Combined immunotherapy with ipilimumab plus nivolumab in metastatic PD-1/PD-L1-refractory Merkel cell carcinoma : a case reportIn: International Journal of Dermatology Jg. 63 (2023) Nr. 2, S. e69 - e71Online Volltext: dx.doi.org/
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Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma ADOREG/TRIM : Analysis of the DeCOG prospective multicenter cohort studyIn: EBioMedicine Jg. 96 (2023) 104774Online Volltext: dx.doi.org/ (Open Access)
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Expression of DNA mismatch repair proteins in melanoma patients treated with immune checkpoint inhibitorsIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 3, S. 1241 - 1247Online Volltext: dx.doi.org/ (Open Access)
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Failure to detect SARS-CoV-2 at RNA and protein level in the sweat of patients with COVID-19In: British Journal of Dermatology: BJD Jg. 188 (2023) Nr. 4, S. 568 - 570Online Volltext: dx.doi.org/
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Identification of Epigenetically Regulated Genes Distinguishing Intracranial from Extracranial Melanoma MetastasesIn: Journal of Investigative Dermatology Jg. 143 (2023) Nr. 7, S. 1233 - 1245.e17Online Volltext: dx.doi.org/ (Open Access)
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Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expressionIn: Journal of Translational Medicine Jg. 21 (2023) Nr. 1, 267Online Volltext: dx.doi.org/ (Open Access)
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Model for End-Stage Liver Disease Correlates with Disease Relapse and Death of Patients with Merkel Cell CarcinomaIn: Cancers Jg. 15 (2023) Nr. 12, 3195Online Volltext: dx.doi.org/ (Open Access)
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Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomicsIn: Frontiers in Oncology Jg. 13 (2023) 1090592Online Volltext: dx.doi.org/ (Open Access)
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Prognostic Performance of Inflammatory Biomarkers Based on Complete Blood Counts in COVID-19 PatientsIn: Viruses Jg. 15 (2023) Nr. 9, 1920Online Volltext: dx.doi.org/ (Open Access)
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Prognostic factors in the primary care of patients with Merkel cell carcinoma : A monocentric cohort study of 108 patients from a tertiary referral centreIn: JEADV Clinical Practice Jg. 2 (2023) Nr. 4, S. 810 - 818Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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S2k Guideline : Merkel cell carcinomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 21 (2023) Nr. 3, S. 305 - 320Online Volltext: dx.doi.org/ (Open Access)
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S2k-Leitlinie – Merkelzellkarzinom – Update 2022In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 21 (2023) Nr. 3, S. 305 - 317Online Volltext: dx.doi.org/ (Open Access)
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S3-Leitlinie “Aktinische Keratose und Plattenepithelkarzinom der Haut“ : Update 2023, Teil 1: Therapie der aktinischen Keratose, Morbus Bowen, Cheilitis actinica, berufsbedingte Erkrankung und VersorgungsstrukturenIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 21 (2023) Nr. 10, S. 1249 - 1262Online Volltext: dx.doi.org/ (Open Access)
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The Antineoplastic Effect of Dimethyl Fumarate on Virus-Negative Merkel Cell Carcinoma Cell Lines : Preliminary ResultsIn: Cancers Jg. 15 (2023) Nr. 2, 547Online Volltext: dx.doi.org/ (Open Access)
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The HDAC inhibitor domatinostat induces type I interferon α in Merkel cell carcinoma by HES1 repressionIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 11, S. 8267 - 8277Online Volltext: dx.doi.org/ (Open Access)
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Undifferentiated pleomorphic sarcoma of the breast with neoplastic fever : Case report and genomic characterizationIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 4, S. 1465 - 1471Online Volltext: dx.doi.org/ (Open Access)
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Adjuvant nivolumab plus ipilimumab or nivolumab alone versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED) : Final results of a randomised, double-blind, phase 2 trialIn: Lancet Jg. 400 (2022) Nr. 10358, S. 1117 - 1129Online Volltext: dx.doi.org/
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Bullous pemphigoid after SARS-CoV-2 vaccination : spike-protein-directed immunofluorescence confocal microscopy and T-cell-receptor studiesIn: British Journal of Dermatology: BJD Jg. 186 (2022) Nr. 4, S. 728 - 731Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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COVID-19 vaccination in advanced skin cancer patients receiving systemic anticancer treatment : A prospective singlecenter study investigating seroconversion ratesIn: Frontiers in Oncology Jg. 12 (2022) 879876Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Characterization of a novel microfluidic platform for the isolation of rare single cells to enable CTC analysis from head and neck squamous cell carcinoma patientsIn: Engineering in Life Sciences Jg. 22 (2022) Nr. 5, S. 391 - 406Online Volltext: dx.doi.org/ (Open Access)
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Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinomaIn: Journal for ImmunoTherapy of Cancer Jg. 10 (2022) Nr. 1, e003198Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Comparison of mutation profiles in primary melanomas and corresponding nodal naevi using next-generation sequencingIn: Clinical and Experimental Dermatology (CED) Jg. 47 (2022) Nr. 2, S. 373 - 380Online Volltext: dx.doi.org/ (Open Access)
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DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinomaIn: Oncogene Jg. 41 (2022) Nr. 1, S. 37 - 45Online Volltext: dx.doi.org/ (Open Access)
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Extended T-Cell Epitope Landscape in Merkel Cell Polyomavirus Large T and Small T Oncoproteins Identified Uniquely in Patients with CancerIn: Journal of Investigative Dermatology Jg. 142 (2022) Nr. 1, S. 239 - 243.e13Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Ipilimumab plus nivolumab in avelumab-refractory Merkel cell carcinoma : A multicenter study of the prospective skin cancer registry ADOREGIn: Journal for ImmunoTherapy of Cancer Jg. 10 (2022) Nr. 11, e005930Online Volltext: dx.doi.org/ (Open Access)
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Knockout of Factor-Inhibiting HIF (Hif1an) in Colon Epithelium Attenuates Chronic Colitis but Does Not Reduce Colorectal Cancer in MiceIn: The Journal of Immunology (JI) Jg. 208 (2022) Nr. 5, S. 1280 - 1291Online Volltext: dx.doi.org/ (Open Access)
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Merkel cell carcinoma of the anorectum : A case report and review of the literatureIn: Clinical Journal of Gastroenterology Jg. 15 (2022) Nr. 4, S. 740 - 745Online Volltext: dx.doi.org/
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Pan-immune-inflammation value independently predicts disease recurrence in patients with Merkel cell carcinomaIn: Journal of Cancer Research and Clinical Oncology Jg. 148 (2022) Nr. 11, S. 3183 - 3189Online Volltext: dx.doi.org/ (Open Access)
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Persister state-directed transitioning and vulnerability in melanomaIn: Nature Communications Jg. 13 (2022) Nr. 1, 3055Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Prognostic Potential of the Baseline Pan-Immune-Inflammation Value and Neutrophil/Lymphocyte Ratio in Stage I to III Melanoma PatientsIn: Cancers Jg. 14 (2022) Nr. 18, 4410Online Volltext: dx.doi.org/ (Open Access)
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Response to Combined Peptide Receptor Radionuclide Therapy and Checkpoint Immunotherapy with Ipilimumab Plus Nivolumab in Metastatic Merkel Cell CarcinomaIn: Journal of Nuclear Medicine (JNM) Jg. 63 (2022) Nr. 3, S. 396 - 398Online Volltext: dx.doi.org/ (Open Access)
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S1-Leitlinie: Kaposi-SarkomIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. 6, S. 892 - 905Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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S2k-Leitlinie – Kutane Lymphome (ICD10 C82–C86) : Update 2021In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. 4, S. 537 - 555Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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Serum neuron‐specific enolase independently predicts outcomes of patients with Merkel cell carcinomaIn: British Journal of Dermatology: BJD Jg. 187 (2022) Nr. 5, S. 806 - 808Online Volltext: dx.doi.org/ (Open Access)
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The pan-immune-inflammation value and systemic immune-inflammation index in advanced melanoma patients under immunotherapyIn: Journal of Cancer Research and Clinical Oncology Jg. 148 (2022) Nr. 11, S. 3103 - 3108Online Volltext: dx.doi.org/ (Open Access)
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Activity of ipilimumab plus nivolumab in avelumab-refractory Merkel cell carcinomaIn: Cancer Immunology, Immunotherapy Jg. 70 (2021) Nr. 7, S. 2087 - 2093Online Volltext: dx.doi.org/ (Open Access)
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Avelumab and cetuximab as a therapeutic combination : An overview of scientific rationale and current clinical trials in cancerIn: Cancer Treatment Reviews Jg. 97 (2021) 102172Online Volltext: dx.doi.org/ (Open Access)
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BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytesIn: Cancer Immunology, Immunotherapy Jg. 70 (2021) Nr. 6, S. 1635 - 1647Online Volltext: dx.doi.org/ (Open Access)
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Case Report: Sustained Remission Due to PD-1-Inhibition in a Metastatic Melanoma Patient With Depleted B CellsIn: Frontiers in Immunology Jg. 12 (2021) 733961Online Volltext: dx.doi.org/ (Open Access)
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Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal TransitionIn: Journal of Investigative Dermatology Jg. 141 (2021) Nr. 7, S. 1675 - 1686.e4Online Volltext: dx.doi.org/ (Open Access)
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Digital Quantification of Tumor PD-L1 Predicts Outcome of PD-1-Based Immune Checkpoint Therapy in Metastatic MelanomaIn: Frontiers in Oncology Jg. 11 (2021) 741993Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Expression of Hedgehog signalling molecules in microcystic adnexal carcinomaIn: Clinical and Experimental Dermatology (CED) Jg. 46 (2021) Nr. 6, S. 1052 - 1057Online Volltext: dx.doi.org/ (Open Access)
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Expression of mismatch repair proteins in merkel cell carcinomaIn: Cancers Jg. 13 (2021) Nr. 11, 3086Online Volltext: dx.doi.org/ (Open Access)
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Expression of potential targets for cell-based therapies on melanoma cellsIn: Life Jg. 11 (2021) Nr. 4, S. 269Online Volltext: dx.doi.org/ (Open Access)
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Grade 4 Neutropenia Secondary to Immune Checkpoint Inhibition : A Descriptive Observational Retrospective Multicenter AnalysisIn: Frontiers in Oncology Jg. 11 (2021) 765608Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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High tumour mutational burden and EGFR/MAPK pathway activation are therapeutic targets in metastatic porocarcinomaIn: British Journal of Dermatology: BJD Jg. 185 (2021) Nr. 6, S. 1186 - 1199Online Volltext: dx.doi.org/ (Open Access)
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Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53In: Oncogene Jg. 40 (2021) Nr. 5, S. 980 - 996Online Volltext: dx.doi.org/ (Open Access)
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Merkel-Zell-KarzinomIn: Der Onkologe Jg. 27 (2021) Nr. 6, S. 569 - 578Online Volltext: dx.doi.org/
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Mismatch repair protein expression and microsatellite instability in cutaneous squamous cell carcinomaIn: Current Oncology Jg. 28 (2021) Nr. 5, S. 3316 - 3322Online Volltext: dx.doi.org/ (Open Access)
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Mutational landscape of virus-and uv-associated merkel cell carcinoma cell lines is comparable to tumor tissueIn: Cancers Jg. 13 (2021) Nr. 4, S. 1 - 16Online Volltext: dx.doi.org/ (Open Access)
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Patched 1 expression in Merkel cell carcinomaIn: The Journal of Dermatology Jg. 48 (2021) Nr. 1, S. 64 - 74Online Volltext: dx.doi.org/ (Open Access)
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Response durability after cessation of immune checkpoint inhibitors in patients with metastatic Merkel cell carcinoma : a retrospective multicenter DeCOG studyIn: Cancer Immunology, Immunotherapy Jg. 70 (2021) Nr. 11, S. 3313 - 3322Online Volltext: dx.doi.org/ (Open Access)
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SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesionIn: Journal of the European Academy of Dermatology and Venereology Jg. 35 (2021) Nr. 3, S. e187 - e189Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Staphylococcus aureus Induces Signal Transducer and Activator of Transcription 5‒Dependent miR-155 Expression in Cutaneous T-Cell LymphomaIn: Journal of Investigative Dermatology Jg. 141 (2021) Nr. 10, S. 2449 - 2458Online Volltext: dx.doi.org/ (Open Access)
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The HDAC Inhibitor Domatinostat Promotes Cell-Cycle Arrest, Induces Apoptosis, and Increases Immunogenicity of Merkel Cell Carcinoma CellsIn: Journal of Investigative Dermatology Jg. 141 (2021) Nr. 4, S. 903 - 912.e4Online Volltext: dx.doi.org/ (Open Access)
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The predictive and prognostic significance of cell-free DNA concentration in melanomaIn: Journal of the European Academy of Dermatology and Venereology Jg. 35 (2021) Nr. 2, S. 387 - 395Online Volltext: dx.doi.org/ (Open Access)
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Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progressionIn: Nature Communications Jg. 12 (2021) Nr. 1, 3895Online Volltext: dx.doi.org/ (Open Access)
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Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapyIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 346Online Volltext: dx.doi.org/ (Open Access)
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Waiving subsequent complete lymph node dissection in melanoma patients with positive sentinel lymph node does not result in worse outcome on 20-year analysisIn: Cancers Jg. 13 (2021) Nr. 21, 5425Online Volltext: dx.doi.org/ (Open Access)
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A digital mRNA expression signature to classify challenging Spitzoid melanocytic neoplasmsIn: FEBS Open Bio Jg. 10 (2020) Nr. 7, S. 1326 - 1341Online Volltext: dx.doi.org/ (Open Access)
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A study on DNA hydroxymethylation in Kaposi sarcoma and cutaneous angiosarcomaIn: Journal of the European Academy of Dermatology and Venereology Jg. 34 (2020) Nr. 12, S. E785 - E787Online Volltext: dx.doi.org/
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Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED) : A randomised, double-blind, placebo-controlled, phase 2 trialIn: Lancet Jg. 395 (2020) Nr. 10236, S. 1558 - 1568Online Volltext: dx.doi.org/
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Altered hydroxymethylation in cutaneous squamous cell carcinoma and keratoacanthomaIn: British Journal of Dermatology: BJD Jg. 183 (2020) Nr. 5, S. 955 - 957Online Volltext: dx.doi.org/ (Open Access)
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Artesunate affects T antigen expression and survival of virus-positive merkel cell carcinomaIn: Cancers Jg. 12 (2020) Nr. 4,Online Volltext: dx.doi.org/ (Open Access)
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Cancer and immune checkpoint inhibitor treatment in the era of SARS-CoV-2 infectionIn: Cancers Jg. 12 (2020) Nr. 11, S. 3383Online Volltext: dx.doi.org/ (Open Access)
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Decline of programmed death-1-positive circulating T regulatory cells predicts more favourable clinical outcome of patients with melanoma under immune checkpoint blockadeIn: British Journal of Dermatology: BJD Jg. 182 (2020) Nr. 5, S. 1214 . 1220Online Volltext: dx.doi.org/ (Open Access)
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Differences in site-specific incidence and relative survival of cutaneous and mucocutaneous genital squamous cell carcinoma in Germany, 2007-2015In: International Journal of Cancer Jg. 147 (2020) Nr. 10, S. 2772 - 2779Online Volltext: dx.doi.org/ (Open Access)
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Does very early timing of lymph node surgery after resection of the primary tumour improve the clinical outcome of patients with melanoma?In: Clinical and Experimental Dermatology (CED) Jg. 45 (2020) Nr. 8, S. 1011 - 1018Online Volltext: dx.doi.org/ (Open Access)
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Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanomaIn: Annals of Oncology Jg. 31 (2020) Nr. 1, S. 144 - 152Online Volltext: dx.doi.org/ (Open Access)
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Expression of Lefty predicts Merkel cell carcinoma-specific deathIn: Journal of the European Academy of Dermatology and Venereology Jg. 34 (2020) Nr. 9, S. 2016 - 2020Online Volltext: dx.doi.org/ (Open Access)
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Expression of Programmed Cell Death Proteins in Kaposi Sarcoma and Cutaneous AngiosarcomaIn: Journal of Immunotherapy Jg. 43 (2020) Nr. 5, S. 169 - 174Online Volltext: dx.doi.org/
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High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanismsIn: PLoS Pathogens Jg. 16 (2020) Nr. 8, S. e1008562Online Volltext: dx.doi.org/ (Open Access)
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Highly expressed MiR-375 is not an intracellular oncogene in merkel cell polyomavirus-associated merkel cell carcinomaIn: Cancers Jg. 12 (2020) Nr. 3,Online Volltext: dx.doi.org/ (Open Access)
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Immune checkpoint inhibition therapy for advanced skin cancer in patients with concomitant hematological malignancy : A retrospective multicenter DeCOG study of 84 patientsIn: Journal for ImmunoTherapy of Cancer Jg. 8 (2020) Nr. 2, S. e000897Online Volltext: dx.doi.org/ (Open Access)
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Impact of a preceding radiotherapy on the outcome of immune checkpoint inhibition in metastatic melanoma : A multicenter retrospective cohort study of the DeCOGIn: Journal for ImmunoTherapy of Cancer Jg. 8 (2020) Nr. 1, S. e000395Online Volltext: dx.doi.org/ (Open Access)
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MCPyV Large T Antigen-Induced Atonal Homolog 1 Is a Lineage-Dependency Oncogene in Merkel Cell CarcinomaIn: Journal of Investigative Dermatology Jg. 140 (2020) Nr. 1, S. 56 - 65.e3Online Volltext: dx.doi.org/ (Open Access)
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MicroRNAs in the pathogenesis, diagnosis, prognosis and targeted treatment of cutaneous T-cell lymphomasIn: Cancers Jg. 12 (2020) Nr. 5, S. 1229Online Volltext: dx.doi.org/ (Open Access)
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Molecular profiling of keratinocyte skin tumors links staphylococcus aureus overabundance and increased human β-defensin-2 expression to growth promotion of squamous cell carcinomaIn: Cancers Jg. 12 (2020) Nr. 3, S. 541Online Volltext: dx.doi.org/ (Open Access)
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On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19In: Journal for ImmunoTherapy of Cancer Jg. 8 (2020) Nr. 2, S. 001145Online Volltext: dx.doi.org/ (Open Access)
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Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell CarcinomaIn: Clinical Cancer Research Jg. 26 (2020) Nr. 9, S. 2257 - 2267Online Volltext: dx.doi.org/ (Open Access)
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S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma (cSCC) – short version, part 2 : epidemiology, surgical and systemic treatment of cSCC, follow‐up, prevention and occupational diseaseIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. 4, S. 400 - 413Online Volltext: dx.doi.org/ (Open Access)
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S3-Leitlinie „Aktinische Keratose und Plattenepithelkarzinom der Haut“ – Kurzfassung, Teil 1 : Diagnostik, Interventionen bei aktinischen Keratosen, Versorgungsstrukturen und QualitätsindikatorenIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. 3, S. 275 - 294Online Volltext: dx.doi.org/ (Open Access)
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S3‐Leitlinie „Aktinische Keratose und Plattenepithelkarzinom der Haut“ – Kurzfassung, Teil 2 : Epidemiologie, chirurgische und systemische Therapie des Plattenepithelkarzinoms, Nachsorge, Prävention und BerufskrankheitIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. 4, S. 400 - 413Online Volltext: dx.doi.org/ (Open Access)
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Staphylococcus aureus alpha-toxin inhibits CD8⁺ T cell-mediated killing of cancer cells in cutaneous T-cell lymphomaIn: OncoImmunology Jg. 9 (2020) Nr. 1, 1751561Online Volltext: dx.doi.org/ (Open Access)
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Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndromeIn: Blood Cancer Journal Jg. 10 (2020) Nr. 5, S. 57Online Volltext: dx.doi.org/ (Open Access)
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Survival of patients with advanced metastatic melanoma : The impact of MAP kinase pathway inhibition and immune checkpoint inhibition - Update 2019In: European Journal of Cancer (EJC) Jg. 130 (2020) S. 126 - 138Online Volltext: dx.doi.org/
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T-Cell Repertoire in Combination with T-Cell Density Predicts Clinical Outcomes in Patients with Merkel Cell CarcinomaIn: Journal of Investigative Dermatology Jg. 140 (2020) Nr. 11, S. 2146 - 2156.e4Online Volltext: dx.doi.org/ (Open Access)
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Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapyIn: The Journal of Clinical Investigation (JCI) Jg. 130 (2020) Nr. 8, S. 4266 - 4281Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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UV-type specific alteration of miRNA expression and its association with tumor progression and metastasis in SCC cell linesIn: Journal of Cancer Research and Clinical Oncology Jg. 146 (2020) Nr. 12, S. 3215 - 3231Online Volltext: dx.doi.org/
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A Brief Communication on Circulating PD-1-positive T-Regulatory Lymphocytes in Melanoma Patients Undergoing Adjuvant Immunotherapy with NivolumabIn: Journal of Immunotherapy Jg. 42 (2019) Nr. 7, S. 265 - 268Online Volltext: dx.doi.org/
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Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphomaIn: Blood Jg. 134 (2019) Nr. 13, S. 1072 - 1083Online Volltext: dx.doi.org/ (Open Access)
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Application of circulating cell-free tumor DNA profiles for therapeutic monitoring and outcome prediction in genetically heterogeneous metastatic melanomaIn: JCO Precision Oncology Jg. 3 (2019)Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines : Integration pattern suggest that large T antigen truncating events occur before or during integrationIn: International Journal of Cancer Jg. 145 (2019) Nr. 4, S. 1020 - 1032Online Volltext: dx.doi.org/ (Open Access)
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Combination of denosumab and immune checkpoint inhibition : experience in 29 patients with metastatic melanoma and bone metastasesIn: Cancer Immunology, Immunotherapy Jg. 68 (2019) Nr. 7, S. 1187 - 1194Online Volltext: dx.doi.org/
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Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibitionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 116 (2019) Nr. 40, S. 20104 - 20114Online Volltext: dx.doi.org/ (Open Access)
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Decreased 5-hydroxymethylcytosine immunoreactivity in primary Merkel cell carcinoma is a strong predictor for disease-specific deathIn: British Journal of Dermatology: BJD (2019)Online Volltext: dx.doi.org/
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Dicer Sequencing, Whole Genome Methylation Profiling, mRNA and smallRNA Sequencing Analysis in Basal Cell CarcinomaIn: Cellular Physiology and Biochemistry Jg. 53 (2019) Nr. 5, S. 760 - 773Online Volltext: dx.doi.org/ (Open Access)
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HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapyIn: Cancer Research Jg. 79 (2019) Nr. 11, S. 2947 - 2961Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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MERTK Acts as a Costimulatory Receptor on Human CD8+ T CellsIn: Cancer Immunology Research Jg. 7 (2019) Nr. 9, S. 1472 - 1484Online Volltext: dx.doi.org/ (Open Access)
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MHC class-I downregulation in PD-1/PD-L1 inhibitor refractory Merkel cell carcinoma and its potential reversal by histone deacetylase inhibition : a case seriesIn: Cancer Immunology, Immunotherapy Jg. 68 (2019) Nr. 6, S. 983 - 990Online Volltext: dx.doi.org/
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Merkel Cell Carcinoma of the Head in a Young African Albino Woman with HIV/HTLV-1 Coinfection Associated with Multiple Squamous Cell CarcinomasIn: Case Reports in Dermatology Jg. 11 (2019) Nr. 1, S. 113 - 122Online Volltext: dx.doi.org/ (Open Access)
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MerkelzellkarzinomIn: Best Practice Onkologie Jg. 14 (2019) Nr. 7/8, S. 312 - 323Online Volltext: dx.doi.org/
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Metastatic Merkel cell carcinoma and myasthenia gravis : contraindication for therapy with immune checkpoint inhibitors?In: Journal for ImmunoTherapy of Cancer Jg. 7 (2019) Nr. 1, S. 141Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Pharmacological inhibition of serine palmitoyl transferase and sphingosine kinase-1/-2 inhibits Merkel Cell Carcinoma cell proliferationIn: Journal of Investigative Dermatology Jg. 139 (2019) Nr. 4, S. 807 - 817Online Volltext: dx.doi.org/ (Open Access)
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S2k guidelines for Merkel cell carcinoma (MCC, neuroendocrine carcinoma of the skin) – update 2018In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 17 (2019) Nr. 5, S. 562 - 576Online Volltext: dx.doi.org/
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S2k-Leitlinie Merkelzellkarzinom (MZK, MCC, neuroendokrines Karzinom der Haut) – Update 2018In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 17 (2019) Nr. 5, S. 562 - 577Online Volltext: dx.doi.org/
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Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4⁺ T cells in cutaneous T-cell lymphomaIn: OncoImmunology Jg. 8 (2019) Nr. 11, e1641387Online Volltext: dx.doi.org/ (Open Access)
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Systematic outperformance of 112 dermatologists in multiclass skin cancer image classification by convolutional neural networksIn: European Journal of Cancer (EJC) Jg. 119 (2019) S. 57 - 65Online Volltext: dx.doi.org/ (Open Access)
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Uveal melanoma : A European network to face the many challenges of a rare cancerIn: Cancers Jg. 11 (2019) Nr. 6, S. 817Online Volltext: dx.doi.org/ (Open Access)
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A short-term in vivo model for Merkel Cell CarcinomaIn: Experimental Dermatology Jg. 27 (2018) Nr. 6, S. 684 - 687Online Volltext: dx.doi.org/ (Open Access)
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Advanced cutaneous squamous cell carcinoma : A retrospective analysis of patient profiles and treatment patterns-Results of a non-interventional study of the DeCOGIn: European Journal of Cancer (EJC) Jg. 96 (2018) S. 34 - 43Online Volltext: dx.doi.org/
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Circulating cell-free miR-375 as surrogate marker of tumor burden in Merkel cell carcinomaIn: Clinical Cancer Research Jg. 24 (2018) Nr. 23, S. 5873 - 5882Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Epidemiology, biology and therapy of Merkel cell carcinoma : conclusions from the EU project IMMOMECIn: Cancer Immunology, Immunotherapy Jg. 67 (2018) Nr. 3, S. 341 - 351Online Volltext: dx.doi.org/ (Open Access)
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Genomic Landscape of Spitzoid Neoplasms Impacting Patient ManagementIn: Frontiers in Medicine Jg. 5 (2018) S. 344Online Volltext: dx.doi.org/ (Open Access)
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MerkelzellkarzinomIn: Der Onkologe Jg. 24 (2018) Nr. 12, S. 1037 - 1049Online Volltext: dx.doi.org/
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Molecular profiling of Spitz nevi identified by digital RNA countingIn: Melanoma Research Jg. 28 (2018) Nr. 6, S. 510 - 520Online Volltext: dx.doi.org/ (Open Access)
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Responses to romidepsin in patients with cutaneous T-cell lymphoma and prior treatment with systemic chemotherapyIn: Leukemia and Lymphoma Jg. 59 (2018) Nr. 4, S. 880 - 887Online Volltext: dx.doi.org/ (Open Access)
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S2k Guidelines – Cutaneous Lymphomas Update 2016 – Part 2: Treatment and Follow-up (ICD10 C82 - C86)In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. 1, S. 112 - 122Online Volltext: dx.doi.org/
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S2k guideline : HPV‐associated lesions of the external genital region and the anus – anogenital warts and precancerous lesions of the vulva, the penis, and the peri‐ and intra‐anal skin (short version)In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. 2, S. 242 - 255Online Volltext: dx.doi.org/
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S2k-Leitlinie – Kutane Lymphome Update 2016 – Teil 2 : Therapie und Nachsorge (ICD10 C82 - C86)In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. 1, S. 112 - 123Online Volltext: dx.doi.org/
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T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexesIn: Nature Biotechnology Jg. 36 (2018) Nr. 12, S. 1191 - 1196Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The association between geographic location and incidence of Merkel cell carcinoma in comparison to melanoma : an international assessmentIn: European Journal of Cancer (EJC) Jg. 94 (2018) S. 47 - 60Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Chemosensitivity-directed therapy compared to dacarbazine in chemo-naive advanced metastatic melanoma : a multicenter randomized phase-3 DeCOG trialIn: OncoTarget Jg. 8 (2017) Nr. 44, S. 76029 - 76043Online Volltext: dx.doi.org/ (Open Access)
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Distribution of TERT promoter mutations in primary and metastatic melanomas in Austrian patientsIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 4, S. 613 - 617Online Volltext: dx.doi.org/
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Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinomaIn: Scientific Reports Jg. 7 (2017) Nr. 1, S. 2290Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Evaluation of real-world treatment outcomes in patients with distant metastatic Merkel cell carcinoma following second-line chemotherapy in EuropeIn: OncoTarget Jg. 8 (2017) Nr. 45, S. 79731 - 79741Online Volltext: dx.doi.org/ (Open Access)
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Fulminant response to combined checkpoint inhibition with ipilimumab plus nivolumab after failure of nivolumab monotherapy in metastatic melanomaIn: European Journal of Cancer (EJC) Jg. 83 (2017) S. 142 - 145Online Volltext: dx.doi.org/
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Imatinib in Dermatofibrosarcoma : Targeted Therapy or Immunotherapy?In: Journal of Investigative Dermatology Jg. 137 (2017) Nr. 2, S. 277 - 279Online Volltext: dx.doi.org/ (Open Access)
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Left-sided laterality of Merkel cell carcinoma in a German population : more than just sun exposureIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 2, S. 347 - 350Online Volltext: dx.doi.org/
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MGMT promoter methylation status in Merkel cell carcinoma: in vitro versus invivoIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 8, S. 1489 - 1497Online Volltext: dx.doi.org/
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Merkel cell carcinomaIn: Nature Reviews Disease Primers Jg. 3 (2017) S. 17077Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Merkel cell carcinoma : Epidemiology, prognosis, therapy and unmet medical needsIn: European Journal of Cancer (EJC) Jg. 71 (2017) S. 53 - 69Online Volltext: dx.doi.org/ (Open Access)
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New developments in the biology and the treatment of metastatic Merkel cell carcinomaIn: Current Opinion in Oncology Jg. 29 (2017) Nr. 3, S. 221 - 226Online Volltext: dx.doi.org/
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Non-reproducible sequence artifacts in FFPE tissue : an experience reportIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 7, S. 1199 - 1207Online Volltext: dx.doi.org/
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Prognostic relevance of high atonal homolog-1 expression in Merkel cell carcinomaIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 1, S. 43 - 49Online Volltext: dx.doi.org/
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Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinomaIn: Critical Reviews in Oncology / Hematology Jg. 116 (2017) S. 99 - 105Online Volltext: dx.doi.org/ (Open Access)
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S2k Guidelines – Cutaneous Lymphomas Update 2016 – Part 1 : Classification and Diagnosis (ICD10 C82 - C86)In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 15 (2017) Nr. 12, S. 1266 - 1273Online Volltext: dx.doi.org/
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S2k-Leitlinie – Kutane Lymphome Update 2016 – Teil 1 : Klassifikation und Diagnostik (ICD10 C82 - C86)In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 15 (2017) Nr. 12, S. 1266 - 1273Online Volltext: dx.doi.org/
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Systematic literature review of efficacy, safety and tolerability outcomes of chemotherapy regimens in patients with metastatic Merkel cell carcinomaIn: Future Oncology Jg. 13 (2017) Nr. 14, S. 1263 - 1279Online Volltext: dx.doi.org/ (Open Access)
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T cell receptor repertoire usage in cancer as a surrogate marker for immune responsesIn: Seminars in Immunopathology Jg. 39 (2017) Nr. 3, S. 255 - 268Online Volltext: dx.doi.org/
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Update on the clinical use of kinase inhibitors in melanomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 15 (2017) Nr. 9, S. 887 - 893Online Volltext: dx.doi.org/
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Adjuvant treatment with pegylated interferon ?-2a versus low-dose interferon ?-2a in patients with high-risk melanoma : a randomized phase III DeCOG trialIn: Annals of Oncology Jg. 27 (2016) Nr. 8, S. 1625 - 1632Online Volltext: dx.doi.org/ (Open Access)
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Evaluation of real world treatment outcomes in patients with metastatic merkel cell carcinoma (MCC) following second line chemotherapyIn: Annals of Oncology Jg. 27 (2016) Nr. Suppl. 6, S. vi397Online Volltext: dx.doi.org/ (Open Access)
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Lack of P-glycoprotein expression in melanoma brain metastases of different melanoma typesIn: Clinical Neuropathology Jg. 35 (2016) Nr. 2, S. 89 - 92Online Volltext: dx.doi.org/
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Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic LatencyIn: Cancer Research Jg. 76 (2016) Nr. 15, S. 4347 - 4358Online Volltext: dx.doi.org/
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Phenotypic tumour cell plasticity as a resistance mechanism and therapeutic target in melanomaIn: European Journal of Cancer (EJC) Jg. 59 (2016) S. 109 - 112Online Volltext: dx.doi.org/
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Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinomaIn: Scientific Reports Jg. 6 (2016) S. 21678Online Volltext: dx.doi.org/ (Open Access)
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SERPINB1 expression is predictive for sensitivity and outcome of cisplatin-based chemotherapy in melanomaIn: OncoTarget Jg. 7 (2016) Nr. 9, S. 10117 - 10132Online Volltext: dx.doi.org/ (Open Access)
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Targeting Both Tumor and Stroma Cells to Treat Melanoma : NIPAWILMAIn: Oncology Research and Treatment Jg. 39 (2016) Nr. 10, S. 652 - 653Online Volltext: dx.doi.org/
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Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and RedistributionIn: Cell Metabolism Jg. 23 (2016) Nr. 3, S. 554 - 562Online Volltext: dx.doi.org/ (Open Access)
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A multicenter DeCOG study on predictors of vemurafenib therapy outcome in melanoma : pretreatment impacts survivalIn: Annals of Oncology Jg. 26 (2015) Nr. 3, S. 573 - 582Online Volltext: dx.doi.org/ (Open Access)
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Acquired BRAF inhibitor resistance : A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanismsIn: European Journal of Cancer (EJC) Jg. 51 (2015) Nr. 18, S. 2792 - 2799Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesisIn: Experimental Dermatology Jg. 24 (2015) Nr. 6, S. 424 - 429Online Volltext: dx.doi.org/
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Clinically significant responses achieved with romidepsin across disease compartments in patients with cutaneous T-cell lymphomaIn: Leukemia and Lymphoma Jg. 56 (2015) Nr. 10, S. 2847 - 2854Online Volltext: dx.doi.org/ (Open Access)
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Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guidelineIn: European Journal of Cancer (EJC) Jg. 51 (2015) Nr. 16, S. 2396 - 2403Online Volltext: dx.doi.org/
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Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guidelineIn: European Journal of Cancer (EJC) Jg. 51 (2015) Nr. 14, S. 1989 - 2007Online Volltext: dx.doi.org/
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Impaired gp100-Specific CD8+ T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma ModelIn: Journal of Investigative Dermatology Jg. 135 (2015) Nr. 11, S. 2785 - 2793Online Volltext: dx.doi.org/ (Open Access)
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Pre-vaccination frequencies of Th17 cells correlate with vaccine-induced T-Cell responses to survivin-derived peptide epitopesIn: PLoS ONE Jg. 10 (2015) Nr. 7, S. e0131934Online Volltext: dx.doi.org/ (Open Access)
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Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancerIn: OncoImmunology Jg. 4 (2015) Nr. 1, 968480Online Volltext: dx.doi.org/
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Denileukin diftitox plus total skin electron beam radiation in patients with treatment-refractory cutaneous T-cell Lymphoma (mycosis fungoides) : report of four casesIn: Acta Dermato-Venereologica Jg. 94 (2014) Nr. 1, S. 94 - 96Online Volltext: dx.doi.org/ (Open Access)
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Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinomaIn: Cancer Immunology Research Jg. 2 (2014) Nr. 11, S. 1071 - 1079Online Volltext: dx.doi.org/
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Fluorescence in situ hybridization and qPCR to detect merkel cell polyomavirus physical status and load in merkel cell carcinomasIn: International Journal of Cancer Jg. 135 (2014) Nr. 12, S. 2804 - 2815Online Volltext: dx.doi.org/ (Open Access)
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Intralesional treatment of stage III metastatic melanoma patients with L19-IL2 results in sustained clinical and systemic immunologic responsesIn: Cancer Immunology Research Jg. 2 (2014) Nr. 7, S. 668 - 678Online Volltext: dx.doi.org/
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Kutane Sarkome : Update ausgewählter Entitäten fibrohistiozytärer und myofibrozytärer MorphologieIn: Der Hautarzt Jg. 65 (2014) Nr. 7, S. 614 - 622Online Volltext: dx.doi.org/
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Kutanes Plattenepithelkarzinom unter Berücksichtigung besonderer PatientengruppenIn: Der Hautarzt Jg. 65 (2014) Nr. 7, S. 590 - 599Online Volltext: dx.doi.org/
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Merkel Cell Carcinoma : Epidemiology, Target, and TherapyIn: Current Dermatology Reports Jg. 3 (2014) Nr. 1, S. 46 - 53Online Volltext: dx.doi.org/ (Open Access)
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Neoadjuvant imatinib in advanced primary or locally recurrent dermatofibrosarcoma protuberans : A multicenter phase II DeCOG Trial with Long-Term Follow-UpIn: Clinical Cancer Research Jg. 20 (2014) Nr. 2, S. 499 - 510Online Volltext: dx.doi.org/
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Presence of Human Polyomavirus 6 in Mutation-Specific BRAF Inhibitor–Induced Epithelial ProliferationsIn: JAMA Dermatology Jg. 150 (2014) Nr. 11, S. 1180 - 1186Online Volltext: dx.doi.org/
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STAT3 single nucleotide polymorphism rs4796793 SNP does not correlate with response to adjuvant IFNα therapy in stage III melanoma patientsIn: Frontiers in Medicine Jg. 1 (2014) Nr. 47,Online Volltext: dx.doi.org/ (Open Access)
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Self-reactive T cells : suppressing the suppressorsIn: Cancer Immunology, Immunotherapy Jg. 63 (2014) Nr. 4, S. 313 - 319Online Volltext: dx.doi.org/
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Somatostatin receptor expression in Merkel cell carcinoma as target for molecular imagingIn: BMC Cancer Jg. 14 (2014) Nr. 1,Online Volltext: dx.doi.org/ (Open Access)
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T-cell responses to oncogenic Merkel cell polyomavirus proteins distinguish patients with Merkel cell carcinoma from healthy donorsIn: Clinical Cancer Research Jg. 20 (2014) Nr. 7, S. 1768 - 1778Online Volltext: dx.doi.org/
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The HSP70 modulator MAL3-101 inhibits Merkel cell carcinomaIn: PLoS ONE Jg. 9 (2014) Nr. 4, S. e92041Online Volltext: dx.doi.org/ (Open Access)
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Tumor-educated myeloid cells : Impact the micro-and macroenvironmentIn: Experimental Dermatology Jg. 23 (2014) Nr. 3, S. 157 - 158Online Volltext: dx.doi.org/
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Upstream mitogen-activated protein kinase (MAPK) pathway inhibition : MEK inhibitor followed by a BRAF inhibitor in advanced melanoma patientsIn: European Journal of Cancer (EJC) Jg. 50 (2014) Nr. 2, S. 406 - 410Online Volltext: dx.doi.org/
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p53 regulation by TRP2 is not pervasive in melanomaIn: PLoS ONE Jg. 9 (2014) Nr. 1, S. e87440Online Volltext: dx.doi.org/ (Open Access)
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Arbeitsgemeinschaft Dermatologische Onkologie (ADO) : Behandlung des fortgeschrittenen PlattenepithelkarzinomsIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 11 (2013) Nr. 7, S. 699Online Volltext: dx.doi.org/
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Brief S2k guidelines : merkel cell carcinomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 11 (2013) Nr. Suppl. 3, S. 29 - 36Online Volltext: dx.doi.org/
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Dacarbazine in melanoma: From a chemotherapeutic drug to an immunomodulating agentIn: Journal of Investigative Dermatology Jg. 133 (2013) Nr. 2, S. 289 - 292Online Volltext: dx.doi.org/ (Open Access)
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Improved survival with MEK inhibition in BRAF-mutated melanomaIn: The New England Journal of Medicine Jg. 367 (2012) Nr. 2, S. 107 - 114Online Volltext: dx.doi.org/
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ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln polymorphisms are independent prognostic factors for the clinical course of melanomaIn: Journal of Investigative Dermatology Jg. 131 (2011) Nr. 6, S. 1280 - 1290Online Volltext: dx.doi.org/ (Open Access)
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Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma : Final results of a randomised phase III study (EORTC 18032)In: European Journal of Cancer (EJC) Jg. 47 (2011) Nr. 10, S. 1476 - 1483Online Volltext: dx.doi.org/
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Sorafenib and pegylated interferon-α2b in advanced metastatic melanoma : A multicenter phase II DeCOG trialIn: Annals of Oncology Jg. 22 (2011) Nr. 7, S. 1667 - 1674Online Volltext: dx.doi.org/
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Multicentre study on standardisation of melanoma cell culture : An initiative of the German Melanoma Research NetworkIn: Pigment Cell and Melanoma Research Jg. 23 (2010) Nr. 2, S. 296 - 298Online Volltext: dx.doi.org/
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Post-transplant monitoring of haematopoietic chimerism in childhood ALL : competitive STR-PCR versus real-time sequence polymorphism (SP)-PCRIn: Bone Marrow Transplantation Jg. 43 (2009) Nr. Suppl. 1, S. S81 - S82Online Volltext: dx.doi.org/
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Keratoepithelin suppresses the progression of experimental human neuroblastomasIn: Cancer Research Jg. 66 (2006) Nr. 10, S. 5314 - 5321Online Volltext: dx.doi.org/
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A low interventional trial addressing the immunological effects of the RANKL-inhibitor Denosumab in combination with dual checkpoint blockade in melanoma patients with bone involvement reveals upregulation of CXCL-13
33. Deutscher Hautkrebskongress (ADO-Jahrestagung) ; 06.–09. September 2023, Hamburg, Germany,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 21 (2023) Nr. S4, Special Issue: Abstractband anlässlich des 33. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 06.–09. September 2023 Hamburg, S. 17Online Volltext: dx.doi.org/ (Open Access) -
A single arm phase II, multicenter trial to evaluate the clinical activity and safety of avelumab plus cetuximab in unresectable stage III or IV cutaneous squamous cell carcinoma : First results from the AliCe study
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Die PD-L1-Expression im Tumor prognostiziert je nach Art des untersuchten Gewebes das Outcome einer Anti-PD-1-basierten Immuntherapie bei metastasiertem Melanom
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MELD-Score korreliert mit Rezidiv und Tod von Patienten mit Merkelzellkarzinom
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Untersuchung des klinischen Verlaufs von Melanompatienten mit einer Super-Response (CR/PR innerhalb von 3 Monaten) unter PD-1-basierter Immuncheckpoint-Inhibition : eine Subgruppen-Analyse der prospektiven multizentrischen Studie ADOREG
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Adjuvant immunotherapy with nivolumab (NIVO) versus observation in completely resected Merkel cell carcinoma (MCC) : Disease-free survival (DFS) results from ADMEC-O, a randomized, open-label phase II trial
ESMO Congress 2022, 9 - 13 September 2022, Paris, France,In: Annals of Oncology Jg. 33 (2022) Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S903Online Volltext: dx.doi.org/ (Open Access) -
Adjuvant nivolumab (NIVO) alone or in combination with ipilimumab (IPI) versus placebo in stage IV melanoma with no evidence of disease (NED) : Overall survival (OS) results of IMMUNED, a randomized, double-blind multi-center phase II DeCOG trial
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Epigenetic mechanisms participate in increased proliferation and survival of melanoma brain metastases
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Epigenetisch-metabolische Vulnerabilität von medikamententoleranten Persisterzellen im MelanomIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. S3, S. 24Online Volltext: dx.doi.org/
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Predictors of long-term survival of stage IV melanoma patients : a multicenter DeCOG study on 539 patients from the prospective skin cancer registry ADOREG
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REINA - Retrospective Multicenter ADOReg Evaluation of Ipilimumab plus Nivolumab in Avelumab-refractory Merkel cell carcinoma
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Comparison of Mutation Profiles in primary Melanomas and nodal Nevi using next Generation SequencingIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 80 - 81
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Expression of DNA-Mismatch-Repair Proteins in Patients with Merkel Cell CarcinomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 32
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Ipilimumab plus Nivolumab in Avelumab-refractory Merkel Cell Carcinoma : A retrospective multicenter AnalysisIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 47 - 48
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Metastatic Porocarcinoma : Genetic Analysis and functional Validation identify new therapeutic StrategiesIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 26
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Open-label Phase-II-Study for Evaluating the Efficacy and Safety of Domatinostat in Combination with Avelumab in advanced, unresectable/metastatic Merkel Cell Carcinoma Patients with Progression under Anti-PD-(L) 1-Antibody Therapy : The MERKLIN 2 StudyIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 26
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Open-label, multicenter Phase II Study to Investigate the Efficacy and Safety of Domatinostat in Combination with Avelumab in Patients with treatment-naive, metastatic Merkel Cell Carcinoma : The MERKLIN 1 StudyIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 45 - 46
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PD-L1-Expression and Mutation Profile in pre-therapeutic Tumor Tissue as Predictors of the Therapeutic Success of PD-1-based Immune Checkpoint Inhibition Therapy in Patients with metastatic Melanoma : Evaluation of the prospective multicentric ADO-Study TRIMIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 19
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PTHrP-induced hypercalcemia Psychosyndrome under Immune Checkpoint Blockade in Patients with penile Squamous Cell CarcinomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 23
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Predictors of Super-response (CR/PR within 3 Months) under PD-1-based Immune Checkpoint Inhibition in metastatic Melanoma : A Subgroup Analysis of the prospective multicenter Study ADOREG TRIMIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 6 - 7
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Tumor PD-L1 expression and gene panel mutational profile as outcome predictors of PD-1-based checkpoint inhibition therapy in metastatic melanoma : A prospective multicenter DeCOG studyIn: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 9568 - 9568Online Volltext: dx.doi.org/
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Tumor PD-L1-Positivity in medical and digital Quantification predicts a favorable Patient Outcome for a PD-1-based Immune Checkpoint-Blockade in metastatic MelanomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 58 - 59
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A phase II, open label study to investigate the efficacy and safety of domatinostat in combination with avelumab in patients with advanced unresectable/metastatic Merkel cell carcinoma progressing on anti-PD-(L)1 antibody therapy : The MERKLIN 2 studyIn: Annals of Oncology Jg. 31 (2020) Nr. Suppl. 4, S. S767 - S768Online Volltext: dx.doi.org/ (Open Access)
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Das reaktive Infiltrat beim kutanen T-Zell-Lymphom ist höchst unbeständig und zeigt keine der typischen Merkmale von AntigenspezifitätIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV10Online Volltext: dx.doi.org/ (Open Access)
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Die digitale Analyse der Tumor PD‐L1 Expression ist ein guter Prädiktor des Therapieerfolgs einer anti‐PD1‐basierten Immuntherapie : Eine Subgruppenanalyse der multizentrischen translationalen Studie ADOREG/TRIMIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV36Online Volltext: dx.doi.org/ (Open Access)
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Ein epithelialer Ursprung des MerkelzellkarzinomsIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV05Online Volltext: dx.doi.org/ (Open Access)
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Eindrucksvolles und schnelles Therapieansprechen eines metastasierten Adnexkarzinoms unter CemiplimabIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV08Online Volltext: dx.doi.org/ (Open Access)
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Immun‐Checkpoint‐Blockade beim Merkelzellkarzinom : Klinische und molekulare Biomarker‐AnalyseIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV22Online Volltext: dx.doi.org/ (Open Access)
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Response durability after cessation of immune checkpoint inhibitors in patients with metastatic Merkel cell carcinoma : A retrospective multicenter retrospective studyIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV24Online Volltext: dx.doi.org/ (Open Access)
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Whole-Exome Sequenzierung von UV- und Virus-assoziierten Merkelzellkarzinom-ZelllinienIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. P93Online Volltext: dx.doi.org/ (Open Access)
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Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphomaIn: European Journal of Cancer (EJC) Jg. 119 (2019) Nr. Suppl. 1, S. S5Online Volltext: dx.doi.org/
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T-cell recognition of large T and small T antigen in Merkel cell polyomavirus-associated cancer
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Adjuvant ipilimumab compared with observation in completely resected Merkel cell carcinoma (ADMEC) : A randomized, multicenter DeCOG/ADO studyIn: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. 9527Online Volltext: dx.doi.org/ (Open Access)
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Adjuvante Therapie des Merkelzellkarzinoms mit Ipilimumab im Vergleich zur Beobachtung (ADMEC) : eine randomisierte, multizentrische ADO‐Studie
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Biomarkers of response to PD‐1 inhibition in Merkel cell carcinoma
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CCR5 Δ32 Polymorphismus als prädiktiver Marker für die Therapie mit Immuncheckpoint‐Inhibitoren beim Melanom
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Die Anzahl mutierter Melanom‐assoziierter Gene und die Expression von PD‐L1 sind unabhängige Prädiktoren der anti‐PD1 Immuntherapie ‐ eine prospektive Registerstudie der ADO (ADOREG/TRIM)In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. S6, S. 7 - 8Online Volltext: dx.doi.org/ (Open Access)
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Eine Dysbakterie auf der Haut von Mycosis fungoides Patienten beeinflusst die Progression der Krankheit durch Polarisierung des reaktiven Infiltrates
Konferenz 28. Deutschen Hautkrebskongresses (ADO‐Jahrestagung); 13.–15. September 2018; Stuttgart,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. S6, S. 4 - 5Online Volltext: dx.doi.org/ (Open Access) -
Epigenetisches Profiling unterscheidet variante MCC‐Zelllinien von klassischen MCC‐ als auch SCC‐Zellinien
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Kombination von Denosumab und einer Immuntherapie mit PD‐1‐Inhibitoren – eine retrospektive Analyse von 29 Patienten mit metastasiertem malignen Melanom und Knochenmetastasen
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Phase I dose-escalation and expansion study of intratumoral CV8102, a RNA-based TLR- and RIG-1 agonist in patients with advanced solid tumorsIn: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 8, S. viii466Online Volltext: dx.doi.org/ (Open Access)
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Therapieversagen der Immuncheckpoint‐Blockade mit PD1‐Antikörpern bei Patienten mit metastasierten Hauttumorerkrankungen und gleichzeitiger Immunsuppression durch eine Chronisch Lymphatische Leukämie
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Zusammenhang zwischen geographischer Lage und Inzidenz des Merkelzellkarzinoms im Vergleich zum Melanom : eine internationale Bewertung
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Zusammenhang zwischen geographischer Lage und Inzidenz des Merkelzellkarzinoms im Vergleich zum Melanom: eine internationale Bewertung
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Adjuvant therapy with pegylated interferon alfa-2a (PEG-IFN) versus low-dose interferon alfa-2a (IFN) in patients with malignant melanoma in stages IIa(T3a): IIIb (AJCC 2002) : Decog-trialIn: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15, suppl., S. 9071Online Volltext: dx.doi.org/
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The Janus-faced role of KDM5B heterogeneity in melanoma : Differentiation as a situational driver of both growth arrest and drug-resistance(2020) 50 SeitenOnline Volltext: dx.doi.org/ (Open Access)
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Cutaneous aspects of leukemiaIn: Braun-Falco's Dermatology / Plewig, Gerd; French, Lars; Ruzicka, Thomas; Kaufmann, Roland; Hertl, Michael (Hrsg.) 2022, S. 1955 - 1963Online Volltext: dx.doi.org/
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AvelumabIn: New Therapies in Advanced Cutaneous Malignancies / Rutkowski, Piotr; Mandalà, Mario (Hrsg.) 2021, S. 313 - 325Online Volltext: dx.doi.org/ (Open Access)
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Clinical characteristics and survival of patients with advanced Merkel cell carcinoma (MCC) treated with avelumab : Analysis of a prospective German MCC registry (MCC TRIM)
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Intra-tumoral CD200/200R protein expression in advanced melanoma patients who underwent treatment with immune checkpoint inhibitors : Preliminary data
33. Deutscher Hautkrebskongress (ADO-Jahrestagung) ; 06.–09. September 2023, Hamburg, Germany,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 21 (2023) Nr. S4, Special Issue: Abstractband anlässlich des 33. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 06.–09. September 2023 Hamburg, S. 120 - 121Online Volltext: dx.doi.org/ (Open Access) -
Therapieoption beim lokal fortgeschrittenen kutanen Plattenepithelkarzinom nach Cemiplimab-Resistenz
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Tumor PD-L1 predicts the outcome of PD-1-based immunotherapy in metastatic melanoma depending on the type of tissue examined
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Expression von DNA-Mismatch-Reparaturproteinen bei Melanompatienten, die mit Immun-Checkpoint-Inhibitoren behandelt werden
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Persister state-directed transitioning and vulnerability in melanoma
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Prognostic Potential of the Baseline Pan-Immune-Inflammation Value and Neutrophil-to-Lymphocyte Ratio in Stage I to III Melanoma Patients
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Undifferenziertes pleomorphes Sarkom der Brust mit paraneoplastischem Fieber : ein Fallbericht und genomische Charakterisierung
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Investigations on the expression of hedgehog signaling molecules in microcystic adnexal carcinoma
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