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Aktuelle Veranstaltungen
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WiSe 2025
Vergangene Veranstaltungen (max. 10)
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SoSe 2025
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Vorlesung des GRK 1739 (mit Gastsprechern)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
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WiSe 2024
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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The vascular endothelium as decision maker in lung injuryIn: Frontiers in Cell and Developmental Biology, Jg. 13, 2025, 1564627DOI, Online Volltext (Open Access)
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Matrix-free human lung organoids derived from induced pluripotent stem cells to model lung injuryIn: Stem Cell Research & Therapy, Jg. 15, 2024, Nr. 1, 468DOI (Open Access)
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Non-small cell lung cancer cells and concomitant cancer therapy induce a resistance-promoting phenotype of tumor-associated mesenchymal stem cellsIn: Frontiers in Oncology, Jg. 14, 2024, 1406268DOI, Online Volltext (Open Access)
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Comparative computational analysis to distinguish mesenchymal stem cells from fibroblastsIn: Frontiers in Immunology, Jg. 14, 2023, 1270493DOI, Online Volltext (Open Access)
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Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infectionIn: Frontiers in Immunology, Jg. 14, 2023, 1227191DOI, Online Volltext (Open Access)
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Protein Levels of Anti-Apoptotic Mcl-1 and the Deubiquitinase USP9x Are Cooperatively Upregulated during Prostate Cancer Progression and Limit Response of Prostate Cancer Cells to RadiotherapyIn: Cancers, Jg. 15, 2023, Nr. 9, 2496DOI, Online Volltext (Open Access)
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HOX genes in stem cells : Maintaining cellular identity and regulation of differentiationIn: Frontiers in Cell and Developmental Biology, Jg. 10, 2022, 1002909DOI, Online Volltext (Open Access)
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Stromal Fibroblasts Counteract the Caveolin-1-Dependent Radiation Response of LNCaP Prostate Carcinoma CellsIn: Frontiers in Oncology, Jg. 12, 2022, 802482DOI, Online Volltext (Open Access)
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Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapyIn: Cell Death and Disease, Jg. 12, 2021, Nr. 7, 694DOI, Online Volltext (Open Access)
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Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinomaIn: Cell Death and Disease, Jg. 12, 2021, Nr. 12, 1162DOI (Open Access)
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Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitorsIn: Communications Biology, Jg. 4, 2021, Nr. 1, 276DOI (Open Access)
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GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancerIn: Cancer Research, Jg. 81, 2021, Nr. 11, S. 2970 – 2982DOI (Open Access)
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Lung Multipotent Stem Cells of Mesenchymal Nature : Cellular Basis, Clinical Relevance, and Implications for Stem Cell TherapyIn: Antioxidants and Redox Signaling, Jg. 35, 2021, Nr. 3, S. 204 – 216
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Lung-resident mesenchymal stem cell fates within lung cancerIn: Cancers, Jg. 13, 2021, Nr. 18, 4637DOI, Online Volltext (Open Access)
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Metformin protects against radiation-induced acute effects by limiting senescence of bronchial-epithelial cellsIn: International Journal of Molecular Sciences (IJMS), Jg. 22, 2021, Nr. 13, 7064DOI, Online Volltext (Open Access)
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The Biomarker Potential of Caveolin-1 in Penile CancerIn: Frontiers in Oncology, Jg. 11, 2021, S. 606122DOI, Online Volltext (Open Access)
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The vascular nature of lung-resident mesenchymal stem cellsIn: Stem Cells Translational Medicine, Jg. 10, 2021, Nr. 1, S. 128 – 143DOI, Online Volltext (Open Access)
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Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor–stroma interactionsIn: Cell Death and Disease, Jg. 11, 2020, Nr. 4, 228DOI (Open Access)
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Cellular Senescence in the Lung : The Central Role of Senescent Epithelial CellsIn: International Journal of Molecular Sciences (IJMS), Jg. 21, 2020, Nr. 9, S. 3279DOI, Online Volltext (Open Access)
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Direct conversion of human fibroblasts into therapeutically active vascular wall-typical mesenchymal stem cellsIn: Cellular and Molecular Life Sciences - CMLS, Jg. 77, 2020, Nr. 17, S. 3401 – 3422DOI, Online Volltext (Open Access)
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Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue ToxicityIn: Frontiers in Oncology, Jg. 10, 2020, S. 554883DOI, Online Volltext (Open Access)
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Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft TumorsIn: Frontiers in Molecular Biosciences, Jg. 6, 2019, 70DOI, Online Volltext (Open Access)
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Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell LossIn: Antioxidants and Redox Signaling, Jg. 30, 2019, Nr. 2, S. 213 – 231
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Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1In: Journal of Clinical Medicine (JCM), Jg. 8, 2019, Nr. 3, 348DOI, Online Volltext (Open Access)
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Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV⁶⁰⁰E inhibition in melanomaIn: European Journal of Cancer (EJC), Jg. 109, 2019, S. 137 – 153
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Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to RadiotherapyIn: Molecular Cancer Therapeutics, Jg. 18, 2019, Nr. 3, S. 656 – 666DOI (Open Access)
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Caveolin-1, cancer and therapy resistanceIn: International Journal of Cancer, Jg. 143, 2018, Nr. 9, S. 2092 – 2104
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Corrigendum : Angelman syndrome-derived neurons display late onset of paternal UBE3A silencingIn: Scientific Reports, Jg. 8, 2018, S. 46952DOI (Open Access)
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Current Strategies to Generate Human Mesenchymal Stem Cells In VitroIn: Stem Cells International, Jg. 2018, 2018, S. 6726185DOI (Open Access)
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Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxiaIn: Cancer Letters, Jg. 439, 2018, S. 24 – 38
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The tumor vascular endothelium as decision maker in cancer therapyIn: Frontiers in Oncology, Jg. 8, 2018, S. 00367DOI, Online Volltext (Open Access)
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iPSCs-based generation of vascular cells : reprogramming approaches and applicationsIn: Cellular and Molecular Life Sciences - CMLS, Jg. 75, 2018, Nr. 8, S. 1411 – 1433DOI (Open Access)
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Activating Akt1 mutations alter DNA double strand break repair and radiosensitivityIn: Scientific Reports, Jg. 7, 2017, S. 42700DOI (Open Access)
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Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC) : Cellular mechanisms of radioresistance and clinical relevanceIn: Cancer Letters, Jg. 386, 2017, S. 87 – 99
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In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem CellsIn: Stem Cell Reports, Jg. 8, 2017, Nr. 4, S. 919 – 932DOI (Open Access)
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Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expressionIn: Antioxidants and Redox Signaling, Jg. 26, 2017, Nr. 11, S. 563 – 582DOI (Open Access)
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Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistanceIn: Scientific Reports, Jg. 7, 2017, S. 41138DOI, Online Volltext (Open Access)
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Angelman syndrome-derived neurons display late onset of paternal UBE3A silencingIn: Scientific Reports, Jg. 6, 2016, S. 30792DOI (Open Access)
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CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration propertiesIn: Cell Adhesion & Migration, Jg. 10, 2016, Nr. 1-2, S. 163 – 178DOI, Online Volltext (Open Access)
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CCN3 signaling is dysregulated in the pregnancy disorder preeclampsiaIn: Journal of Reproductive Immunology, Jg. 115, 2016, S. 71 – 71
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Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung FibrosisIn: Cancer Research, Jg. 76, 2016, Nr. 10, S. 3045 – 3056DOI (Open Access)
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RHAMM splice variants confer radiosensitivity in human breast cancer cell linesIn: OncoTarget, Jg. 7, 2016, Nr. 16, S. 21428 – 21440DOI (Open Access)
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Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling HypoxiaIn: Antioxidants and Redox Signaling, Jg. 25, 2016, Nr. 2, S. 89 – 107
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Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasisIn: Antioxidants and Redox Signaling, Jg. 24, 2016, Nr. 2, S. 53 – 69
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Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature within the Process of Vascular Remodeling: Cellular Basis, Clinical Relevance, and Implications for Stem Cell TherapyIn: Stem Cells International, Jg. 2016, 2016, S. 1905846DOI (Open Access)
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Endothelial Caveolin-1 regulates the radiation response of epithelial prostate tumorsIn: Oncogenesis, Jg. 4, 2015, S. e148DOI (Open Access)
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Fanconi anemia, complementation group A (FancA) overexpression confers radioresistance to oral keratinocytesIn: European Journal of Cancer (EJC), Jg. 51, 2015, Nr. Suppl.3, S. 121 – S121
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CCN3 (NOV) : A key player in trophoblast differentiation promoting cell cycle exit and migration of extravillous trophoblast cells and its role in preeclampsiaIn: Placenta, Jg. 35, 2014, Nr. 9, S. A108
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Importance of stromal caveolin-1 for tumor growth and radiosensitivity of epithelial tumorsIn: European Journal of Cancer (EJC), Jg. 50, 2014, Nr. 5 Suppl., S. 224
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Mesenchymal stem cell therapy antagonizes radiation-induced endothelial cell damage and metastasisIn: European Journal of Cancer (EJC), Jg. 50, 2014, Nr. Suppl. 5, S. 221
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Nestin(+) tissue-resident multipotent stem cells contribute to tumor progression by differentiating into pericytes and smooth muscle cells resulting in blood vessel remodelingIn: Frontiers in Oncology, 2014, Nr. 4, S. 169DOI (Open Access)
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Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve DevelopmentIn: PLoS ONE, Jg. 8, 2013, Nr. 4, S. e60244DOI (Open Access)
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Hox genes are involved in vascular wall-resident multipotent stem cell differentiation into smooth muscle cellsIn: Scientific Reports, Jg. 3, 2013, S. 2178DOI (Open Access)
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Tumor vessel stabilization and remodeling by anti-angiogenic therapy with bevacizumabIn: Histochemistry and Cell Biology, Jg. 137, 2012, Nr. 3, S. 391 – 401
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Vascular wall as a reservoir for different types of stem and progenitor cellsIn: Antioxidants and Redox Signaling, Jg. 15, 2011, Nr. 4, S. 981 – 995
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Vascular wall-resident CD44+ multipotent stem cells give rise to pericytes and smooth muscle cells and contribute to new vessel maturationIn: PLoS ONE, Jg. 6, 2011, Nr. 5, S. e20540DOI (Open Access)
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Liver sinusoidal endothelium : a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1In: Hepatology, Jg. 52, 2010, Nr. 1, S. 313 – 326
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How stromal Caveolin-1 alters the radiation response of prostate tumors
24. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 21. Juni 2018 - 24. Juni 2018, Leipzig,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 194, 2018, Nr. 1 Supplement, Abstracts DEGRO 2018, S. S171 – S172DOI (Open Access) -
Loss or therapeutic inhibition of extracellular adenosine production by ecto-5 -nucleotidase (CD73) attenuates radiation-induced lung fibrosis
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 191, 2015, Nr. Suppl.1, S. 14 – S15 -
Loss or therapeutic inhibition of extracellular adenosine production by ecto-5 -nucleotidase(CD73) attenuates radiation-induced lung fibrosis
European Cancer Congress (ECC 2015), 25.-29.09.2015, Wien,In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 51, 2015, Nr. Supplement 3, S. S117 – S118 -
Signalling networks associated with FancA mediated radioresistance in cells of head and neck squamous cell carcinoma
21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 191, 2015, Nr. Suppl.1, S. 77 -
The influence of FancA overexpression on radioresistance in oral keratinocytes and HNSCC cellsIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 191, 2015, Nr. Suppl.1, S. 90
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Mesenchymale Stammzell-Therapie zur Radioprotektion des Lungen-Gewebes
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 3. bis 6. Juli 2014, Düsseldorf,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 190, 2014, Nr. Suppl. 1, S. 15 -
Matricellular CCN1 and CCN3 proteins are key regulators at the fetal-maternal interface by promoting cell cycle exit and migration of extravillous trophoblast cellsIn: Placenta. Amsterdam: Elsevier, Jg. 34, 2013, S. A87
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Complex Spheroids as an Alternative : In Vivo-Like 3D Model for Investigating the Impact of Stromal Cells on the Radiation Response of TumorsIn: Organoids: Models for Development and Disease / Turksen, Kursad (Hrsg.). Heidelberg: Springer, 2025, S. 257 – 266
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Normalization of the tumor vasculatureIn: Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside / Chatterjee, Shampa (Hrsg.). London: Elsevier, 2021, S. 91 – 104
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Improved isolation of human vascular wall–resident mesenchymal stem cellsIn: Stem Cells and Tissue Repair: Methods and Protocols / Kioussi, Chrissa (Hrsg.). New York: Humana, 2020, S. 71 – 81
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In Vitro Generation of Vascular Wall-Typical Mesenchymal Stem Cells (VW-MSC) from Murine Induced Pluripotent Stem Cells Through VW-MSC-Specific Gene TransferIn: Stem Cells and Tissue Repair: Methods and Protocols / Kioussi, Chrissa (Hrsg.). New York: Humana, 2020, S. 83 – 97
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Identifizierung molekularer und zellulärer Determinanten der vaskulären Differenzierung und Stabilisierung von angiogenen Tumorgefäßen als potentielle Targets einer anti-angiogenen TherapieDuisburg, Essen, 2015