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Funktionen
- Privatdozent/in, Klinik für Dermatologie
Aktuelle Veranstaltungen
- 2020 WS
Vergangene Veranstaltungen (max. 10)
- 2020 SS
- 2019 WS
- 2019 SS
- 2018 WS
- 2018 SS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma RegressionIn: Frontiers in Immunology Jg. 11 (2020) S. 1849
ISSN: 1664-3224Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanomaIn: Nature Medicine Jg. 26 (2020) Nr. 7, S. 1147
ISSN: 1546-170X; 1078-8956Online Volltext: dx.doi.org/ (Open Access) -
Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens Jg. 16 (2020) Nr. 3, S. e1008340
ISSN: 1553-7374; 1553-7366Online Volltext: dx.doi.org/ (Open Access) -
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitopeIn: European Journal of Immunology: EJI Jg. 50 (2020) Nr. 2, S. 270 - 283
ISSN: 1521-4141; 0014-2980Online Volltext: dx.doi.org/ (Open Access) -
Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanomaIn: Annals of Oncology Jg. 31 (2020) Nr. 1, S. 144 - 152
ISSN: 1569-8041; 0923-7534Online Volltext: dx.doi.org/ -
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapyIn: The Journal of Clinical Investigation Jg. 130 (2020) Nr. 8, S. 4266 - 4281
ISSN: 1558-8238; 0021-9738Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
The predictive and prognostic significance of cell-free DNA concentration in melanomaIn: Journal of the European Academy of Dermatology and Venereology (2020)
ISSN: 1468-3083; 0926-9959Online Volltext: dx.doi.org/ (Open Access) -
The predictive and prognostic significance of cell-free DNA concentration in melanomaIn: Journal of the European Academy of Dermatology and Venereology (JEADV) (2020)
ISSN: 1468-3083; 0926-9959Online Volltext: dx.doi.org/ (Open Access) -
Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillanceIn: Cancer Immunology, Immunotherapy Jg. 68 (2019) Nr. 3, S. 479 - 488
ISSN: 1432-0851; 0340-7004Online Volltext: dx.doi.org/ -
Clinical and genetic analysis of melanomas arising in acral sitesIn: European Journal of Cancer Jg. 119 (2019) S. 66 - 76
ISSN: 1879-0852; 0959-8049Online Volltext: dx.doi.org/ -
Direct RIG-I activation in human NK cells induces TRAIL-dependent cytotoxicity toward autologous melanoma cellsIn: International Journal of Cancer Jg. 144 (2019) Nr. 7, S. 1645 - 1656
ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/ -
Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53In: Theranostics Jg. 9 (2019) Nr. 21, S. 6047 - 6062
ISSN: 1838-7640Online Volltext: dx.doi.org/ (Open Access) -
Frequent Occurrence of NRAS and BRAF Mutations in Human Acral NaeviIn: Cancers Jg. 11 (2019) Nr. 4, S. 546
ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
High PD-1 or PD-L1 Concentrations in the Serum of Melanoma Patients are predictive for reduced Therapeutic Success of PD-1 InhibitionIn: Journal der Deutschen Dermatologischen Gesellschaft Jg. 17 (2019) Nr. Suppl. 5, S. 7 - 7
ISSN: 1610-0379; 1610-0387 -
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanomaIn: Nature Medicine Jg. 25 (2019) Nr. 12, S. 1916 - 1927
ISSN: 1078-8956; 1546-170XOnline Volltext: dx.doi.org/ (Open Access) -
The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in MelanomaIn: Cell Reports Jg. 27 (2019) Nr. 12, S. 3573 - 3586.e7
ISSN: 2211-1247Online Volltext: dx.doi.org/ (Open Access) -
Evolution of melanoma cross-resistance to CD8⁺ T cells and MAPK inhibition in the course of BRAFi treatmentIn: OncoImmunology Jg. 7 (2018) Nr. 8, S. e1450127
ISSN: 2162-402X; 2162-4011Online Volltext: dx.doi.org/ -
Immunoassays for scarce tumour-antigens in exosomes : Detection of the human NKG2D-Ligand, MICA, in tetraspanin-containing nanovesicles from melanomaIn: Journal of Nanobiotechnology Jg. 16 (2018) Nr. 1, S. 47
ISSN: 1477-3155Online Volltext: dx.doi.org/ (Open Access) -
Impaired NK cell recognition of vemurafenib-treated melanoma cells is overcome by simultaneous application of histone deacetylase inhibitorsIn: OncoImmunology Jg. 7 (2018) Nr. 2, S. e1392426
ISSN: 2162-402X; 2162-4011Online Volltext: dx.doi.org/ -
NF1 mutations in conjunctival melanomaIn: The British Journal of Cancer: BJC Jg. 118 (2018) Nr. 9, S. 1243 - 1247
ISSN: 1532-1827; 0007-0920Online Volltext: dx.doi.org/ (Open Access) -
Tumor CDKN2A-Associated JAK2 Loss and Susceptibility to Immunotherapy ResistanceIn: Journal of the National Cancer Institute Jg. 110 (2018) Nr. 6, S. 677 - 681
ISSN: 0198-0157; 0027-8874Online Volltext: dx.doi.org/ -
Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications Jg. 8 (2017) S. 15440
ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access) -
Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative FunctionIn: Stem Cell Reports Jg. 9 (2017) Nr. 3, S. 985 - 998
ISSN: 2213-6711Online Volltext: dx.doi.org/ (Open Access) -
Activated tissue-resident mesenchymal stromal cells regulate natural killer cell immune and tissue regenerative functionIn: European Journal of Immunology Jg. 47 (2017) Nr. S2, Special Issue:47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 62
ISSN: 0014-2980Online Volltext: dx.doi.org/ -
Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue neviIn: Modern Pathology Jg. 30 (2017) Nr. 3, S. 350 - 356
ISSN: 1530-0285; 0893-3952Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinomaIn: Scientific Reports Jg. 7 (2017) Nr. 1, S. 2290
ISSN: 2045-2322Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infectionIn: Scientific Reports Jg. 7 (2017) S. 7785
ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access) -
Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris MelanomaIn: Investigative Ophthalmology & Visual Science Jg. 58 (2017) Nr. 9, S. 3464 - 3470
ISSN: 1552-5783; 0146-0404Online Volltext: dx.doi.org/ (Open Access) -
HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma modelIn: OncoTarget Jg. 8 (2017) Nr. 17, S. 28312 - 28327
ISSN: 1949-2553Online Volltext: dx.doi.org/ (Open Access) -
SF3B1 and BAP1 mutations in blue nevus-like melanomaIn: Modern Pathology Jg. 30 (2017) Nr. 7, S. 928 - 939
ISSN: 1530-0285; 0893-3952Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformationIn: Oncogene Jg. 36 (2017) Nr. 36, S. 5110 - 5121
ISSN: 0950-9232; 1476-5594Online Volltext: dx.doi.org/ -
Development of a rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluidsIn: Journal of Extracellular Vesicles Jg. 5 (2016) Nr. 1, S. 31803
ISSN: 2001-3078Online Volltext: dx.doi.org/ (Open Access) -
Exposure to Melan-A/MART-126-35 tumor epitope specific CD8(+)T cells reveals immune escape by affecting the ubiquitin-proteasome system (UPS)In: Scientific Reports Jg. 6 (2016) S. 25208
ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access) -
Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic LatencyIn: Cancer Research Jg. 76 (2016) Nr. 15, S. 4347 - 4358
ISSN: 0008-5472; 1538-7445Online Volltext: dx.doi.org/ -
Phenotypic tumour cell plasticity as a resistance mechanism and therapeutic target in melanomaIn: European Journal of Cancer Jg. 59 (2016) S. 109 - 112
ISSN: 0959-8049Online Volltext: dx.doi.org/ -
The Influence of HLA and KIR Genes on Malignant Melanoma Development and ProgressionIn: Archivum Immunologiae et Therapiae Experimentalis Jg. 64 (2016) Nr. Suppl. 1, S. 73 - 81
ISSN: 1661-4917; 0004-069XOnline Volltext: dx.doi.org/ -
Analysis of SDHD promoter mutations in various types of melanomaIn: OncoTarget Jg. 6 (2015) Nr. 28, S. 25868 - 25882
ISSN: 1949-2553Online Volltext: dx.doi.org/ (Open Access) -
Analysis of SDHD promoter mutations in various types of melanomaIn: Journal der Deutschen Dermatologischen Gesellschaft Jg. 13 (2015) Nr. Suppl. 2, S. 11
ISSN: 1610-0379; 1610-0387; 1563-2571; 0301-0481Online Volltext: dx.doi.org/ -
Deciphering the genetic evolution of T-cell resistance in melanomaIn: OncoImmunology Jg. 4 (2015) Nr. 5, S. e1005510
ISSN: 2162-402X; 2162-4011Online Volltext: dx.doi.org/ (Open Access) -
Frequent TERT Promoter Mutations in Ocular Surface Squamous NeoplasiaIn: Investigative Ophthalmology & Visual Science Jg. 56 (2015) Nr. 10, S. 5854 - 5861
ISSN: 0146-0404Online Volltext: dx.doi.org/ (Open Access) -
The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35-specific T-cell recognitionIn: European Journal of Immunology Jg. 45 (2015) Nr. 12, S. 3257 - 3268
ISSN: 0014-2980Online Volltext: dx.doi.org/ (Open Access) -
Differential influence of vemurafenib and dabrafenib on patients' lymphocytes despite similar clinical efficacy in melanomaIn: Annals of Oncology Jg. 25 (2014) Nr. 3, S. 747 - 753
ISSN: 1569-8041Online Volltext: dx.doi.org/ -
Expression of stress ligands of the immunoreceptor NKG2D in melanoma : regulation and clinical significanceIn: European Journal of Cell Biology Jg. 93 (2014) Nr. 1-2, S. 49 - 54
ISSN: 0171-9335Online Volltext: dx.doi.org/ -
Genetic evolution of T-cell resistance in the course of melanoma progressionIn: Clinical Cancer Research Jg. 20 (2014) Nr. 24, S. 6593 - 6604
ISSN: 1078-0432Online Volltext: dx.doi.org/ -
Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30In: Cancer Research Jg. 74 (2014) Nr. 13, S. 3429 - 3440
ISSN: 1538-7445Online Volltext: dx.doi.org/ -
Dacarbazine in melanoma: From a chemotherapeutic drug to an immunomodulating agentIn: Journal of Investigative Dermatology Jg. 133 (2013) Nr. 2, S. 289 - 292
ISSN: 0022-202X; 1523-1747Online Volltext: dx.doi.org/ (Open Access) -
Immunological consequences of selective BRAF inhibitors in malignant melanoma : Neutralization of myeloid-derived suppressor cellsIn: OncoImmunology Jg. 2 (2013) Nr. 8, S. e25218
ISSN: 2162-402XOnline Volltext: dx.doi.org/ (Open Access) -
New developments in biomarkers for melanomaIn: Current Opinion in Oncology Jg. 25 (2013) Nr. 2, S. 145 - 151
ISSN: 1040-8746; 1531-703XOnline Volltext: dx.doi.org/ -
Survivin blockade sensitizes rhabdomyosarcoma cells for lysis by fetal acetylcholine receptor-redirected T cellsIn: American Journal of Pathology Jg. 182 (2013) Nr. 6, S. 2121 - 2131
ISSN: 1525-2191; 0002-9440Online Volltext: dx.doi.org/ -
Vemurafenib reverses immunosuppression by myeloid derived suppressor cellsIn: International Journal of Cancer Jg. 133 (2013) Nr. 7, S. 1653 - 1663
ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/ -
Vemurafenib reverses immunosuppression by myeloid derived suppressor cellsIn: Cancer Research Jg. 73 (2013) Nr. 8 Suppl., S. 4714
ISSN: 0008-5472Online Volltext: dx.doi.org/ -
Gegen den Hautkrebs : Forschung zur Überwindung immuntherapeutischer Hürden beim malignen MelanomIn: Unikate: Berichte aus Forschung und Lehre (2012) Nr. 42: Translationale Krebsforschung: Auf dem Weg zu neuen Therapien, S. 32 - 41
ISBN: 978-3-934359-42-0 ISSN: 0944-6060; 1869-3881Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Implication of the β2-microglobulin gene in the generation of tumor escape phenotypesIn: Cancer Immunology, Immunotherapy Jg. 61 (2012) Nr. 9, S. 1359 - 1371
ISSN: 0340-7004; 1432-0851Online Volltext: dx.doi.org/ -
The efficiency of human cytomegalovirus pp65₄₉₅₋₅₀₃ CD8 ⁺T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidasesIn: The Journal of Immunology Jg. 189 (2012) Nr. 2, S. 529 - 538
ISSN: 1550-6606; 0022-1767Online Volltext: dx.doi.org/ -
Tumor Suppressive MicroRNAs miR-34a/c Control Cancer Cell Expression of ULBP2, a Stress-Induced Ligand of the Natural Killer Cell Receptor NKG2DIn: Cancer Research Jg. 72 (2012) Nr. 2, S. 460 - 471
ISSN: 0008-5472; 1538-7445Online Volltext: dx.doi.org/ -
Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2DIn: OncoImmunology Jg. 1 (2012) Nr. 4, S. 535 - 536
ISSN: 2162-402XOnline Volltext: dx.doi.org/ -
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopesIn: Nature Immunology Jg. 12 (2011) Nr. 1, S. 45 - 53
ISSN: 1529-2908; 1529-2916Online Volltext: dx.doi.org/ -
Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumorsIn: Immunogenetics Jg. 63 (2011) Nr. 2, S. 65 - 71
ISSN: 1432-1211; 0093-7711Online Volltext: dx.doi.org/ -
Adoptive T-Zell-Therapie des RhabdomyosarkomsIn: Der Pathologe Jg. 31 (2010) Nr. SUPPL. 2, S. 215 - 220
ISSN: 1432-1963; 0172-8113Online Volltext: dx.doi.org/ -
MMP19 is upregulated during melanoma progression and increases invasion of melanoma cellsIn: Modern Pathology Jg. 23 (2010) Nr. 4, S. 511 - 521
ISSN: 0893-3952; 1530-0285Online Volltext: dx.doi.org/ -
Multicentre study on standardisation of melanoma cell culture : An initiative of the German Melanoma Research NetworkIn: Pigment Cell and Melanoma Research Jg. 23 (2010) Nr. 2, S. 296 - 298
ISSN: 1755-148X; 1755-1471Online Volltext: dx.doi.org/ -
Screening of Human Tumor Antigens for CD4+ T Cell Epitopes by Combination of HLA-Transgenic Mice, Recombinant Adenovirus and Antigen Peptide LibrariesIn: PLoS ONE Jg. 5 (2010) Nr. 11, S. e14137
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Distinct melanoma differentiation trajectories driven by MAPKi associate with activation of CD8+tumor-infiltrating lymphocytesIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV17
ISSN: 1563-2571; 1610-0387; 0301-0481; 1610-0379Online Volltext: dx.doi.org/ -
Tumorzell‐intrinsiche Aktivierung des Immunrezeptors RIG‐I in Kombination mit Immun‐Checkpoint‐Blockade verbessert anti‐Tumor T‐ZellantwortenIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV18
ISSN: 1610-0379; 1610-0387Online Volltext: dx.doi.org/ -
Evolution of cross‐resistance to CD8+ T cells in the course of BRAF and MEK inhibitor treatment in BRAFV600E melanoma
28. Deutschen Hautkrebskongresses (ADO‐Jahrestagung); 13.–15. September 2018; Stuttgart,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. 6, S. 53
ISSN: 1563-2571; 0301-0481Online Volltext: dx.doi.org/ -
The era of checkpoint inhibition : Lessons learned from melanomaIn: Current Immunotherapeutic Strategies in Cancer Theobald, Matthias; (Hrsg.) 2020, S. 169 - 187
ISBN: 978-3-030-23764-6; 978-3-030-23765-3Online Volltext: dx.doi.org/ -
The Janus-faced role of KDM5B heterogeneity in melanoma : Differentiation as a situational driver of both growth arrest and drug-resistance(2020) 50 Seiten 50 Seiten
Online Volltext: dx.doi.org/ (Open Access)