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PD Dr. rer. nat. Annette Paschen

Funktionen

  • Privatdozent/in, Klinik für Dermatologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Philip, Manuel; Puppel, Sven Holger; Stiller, Mathias; Paschen, Annette; Rösch, Alexander; Zaremba, Anne; Schadendorf, Dirk; Horn, Susanne
    Database for queries of melanoma cohorts with molecular and clinical data
    In: Pigment Cell and Melanoma Research Jg. 36 (2023) Nr. 2, S. 252 - 258
    ISSN: 1755-1471; 1755-148X
    Online Volltext: dx.doi.org/ (Open Access)
  • Stupia, Simone; Heeke, Christina; Brüggemann, Alicia; Zaremba-Montenari, Anne; Thier, Beatrice; Kretz, Julia; Sucker, Antje; Philip, Manuel; Zelinskyy, Gennadiy; Ferrone, Soldano; Rösch, Alexander; Horn, Susanne; Hadaschik, Eva; Schadendorf, Dirk; Trilling, Mirko; Dittmer, Ulf; Griewank, Klaus; Zhao, Fang; Paschen, Annette
    HLA class II loss and JAK1/2 deficiency coevolve in melanoma leading to CD4 T cell and IFNγ cross-resistance
    In: Clinical Cancer Research (2023) in press
    ISSN: 1557-3265; 1078-0432
    Online Volltext: dx.doi.org/
  • López-Borrego, Silvia; Campos-Silva, Carmen; Sandúa, Amaia; Camino, Tamara; Téllez-Pérez, Lucía; Alegre, Estibaliz; Beneitez, Alexandra; Jara-Acevedo, Ricardo; Paschen, Annette; Pardo, María; González, Álvaro; Valés-Gómez, Mar
    MAPK inhibitors dynamically affect melanoma release of immune NKG2D-ligands, as soluble protein and extracellular vesicle-associated
    In: Frontiers in Cell and Developmental Biology Jg. 10 (2023)
    ISSN: 2296-634X
    Online Volltext: dx.doi.org/ (Open Access)
  • Immisch, Lena; Papafotiou, George; Gallarín Delgado, Nerea; Scheuplein, Vivian; Paschen, Annette; Blankenstein, Thomas; Willimsky, Gerald
    Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors
    In: Frontiers in Immunology Jg. 14 (2023)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Paschen, Annette; Melero, Ignacio; Ribas, Antoni
    Central Role of the Antigen-Presentation and Interferon-γ Pathways in Resistance to Immune Checkpoint Blockade
    In: Annual Review of Cancer Biology Jg. 6 (2022) S. 85 - 102
    ISSN: 2472-3428
    Online Volltext: dx.doi.org/ (Open Access)
  • Albrecht, Lea Jessica; Höwner, Anna; Griewank, Klaus; Lueong, Smiths S.; von Neuhoff, Nils; Horn, Peter; Sucker, Antje; Paschen, Annette; Livingstone, Elisabeth; Ugurel, Selma; Zimmer, Lisa; Horn, Susanne; Siveke, Jens; Schadendorf, Dirk; Váraljai, Renáta; Rösch, Alexander
    Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype
    In: Clinical and Translational Medicine Jg. 12 (2022) Nr. 11,
    ISSN: 2001-1326
    Online Volltext: dx.doi.org/ (Open Access)
  • Thielmann, Carl Maximilian; Matull, Johanna; Roth, Sebastian; Placke, Jan-Malte; Chorti, Eleftheria; Zaremba, Anne; Lodde, Georg; Jansen, Philipp; Krefting, Frederik; Kretz, Julia; Möller, Inga; Sucker, Antje; Paschen, Annette; Livingstone, Elisabeth; Zimmer, Lisa; Ugurel, Selma; Schadendorf, Dirk; Hadaschik, Eva; Griewank, Klaus
    Genetic and Clinical Characteristics of ARID1A Mutated Melanoma Reveal High Tumor Mutational Load without Implications on Patient Survival
    In: Cancers Jg. 14 (2022) Nr. 9,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zaremba, Anne; Jansen, Philipp; Murali, Rajmohan; Mayakonda, Anand; Riedel, Anna; Krahl, Dieter; Burkhardt, Hans; John, Stefan; Géraud, Cyrill; Philip, Manuel; Kretz, Julia; Möller, Inga; Stadtler, Nadine; Sucker, Antje; Paschen, Annette; Ugurel, Selma; Zimmer, Lisa; Livingstone, Elisabeth; Horn, Susanne; Plass, Christoph; Schadendorf, Dirk; Hadaschik, Eva; Lutsik, Pavlo; Griewank, Klaus
    Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions
    In: Cancers Jg. 14 (2022) Nr. 17,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zaremba-Montenari, Anne; Jansen, Philipp; Murali, Rajmohan; Mayakonda, Anand; Riedel, Anna; Philip, Manuel; Rose, Christian; Schaller, Jörg; Müller, Hansgeorg; Kutzner, Heinz; Möller, Inga; Stadtler, Nadine; Kretz, Julia; Sucker, Antje; Bankfalvi, Agnes; Livingstone, Elisabeth; Zimmer, Lisa; Horn, Susanne; Paschen, Annette; Plass, Christoph; Schadendorf, Dirk; Hadaschik, Eva; Lutsik, Pavlo; Griewank, Klaus
    Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors
    In: International Journal of Cancer (2022) in press
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/ (Open Access)
  • Thier, Beatrice; Zhao, Fang; Stupia, Simone; Brüggemann, Alicia; Koch, Johannes; Schulze, Nina; Horn, Susanne; Coch, Christoph; Hartmann, Gunther; Sucker, Antje; Schadendorf, Dirk; Paschen, Annette
    Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity
    In: Journal for ImmunoTherapy of Cancer Jg. 10 (2022) Nr. 6,
    ISSN: 2051-1426
    Online Volltext: dx.doi.org/ (Open Access)
  • Chauvistré, Heike; Shannan, Batool; Daignault-Mill, Sheena M.; Ju, Robert J.; Picard, Daniel; Egetemaier, Stefanie; Váraljai, Renáta; Gibhardt, Christine S.; Sechi, Antonio; Kaschani, Farnusch; Keminer, Oliver; Stehbens, Samantha J.; Liu, Qin; Yin, Xiangfan; Jeyakumar, Kirujan; Vogel, Felix C. E.; Krepler, Clemens; Rebecca, Vito W.; Kubat, Linda; Lueong, Smiths S.; Forster, Jan; Horn, Susanne; Remke, Marc; Ehrmann, Michael; Paschen, Annette; Becker, Jürgen; Helfrich, Iris; Rauh, Daniel; Kaiser, Markus; Gul, Sheraz; Herlyn, Meenhard; Bogeski, Ivan; Rodríguez-López, José Neptuno; Haass, Nikolas K.; Schadendorf, Dirk; Rösch, Alexander
    Persister state-directed transitioning and vulnerability in melanoma
    In: Nature Communications Jg. 13 (2022) Nr. 1,
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Cheung, Phyllis F.; Yang, JiaJin; Fang, Rui; Borgers, Arianna; Krengel, Kirsten; Stoffel, Anne; Althoff, Kristina; Yip, Chi Wai; Siu, Elaine H. L.; Ng, Linda W. C.; Lang, Karl S.; Cham, Lamin B.; Engel, Daniel Robert; Soun, Camille; Cima, Igor; Scheffler, Björn; Striefler, Jana K.; Sinn, Marianne; Bahra, Marcus; Pelzer, Uwe; Oettle, Helmut; Markus, Peter; Smeets, Esther M. M.; Aarntzen, Erik H. J. G.; Savvatakis, Konstantinos; Liffers, Sven-Thorsten; Lueong, Smiths S.; Neander, Christian; Bazarna, Anna; Zhang, Xin; Paschen, Annette; Crawford, Howard C.; Chan, Anthony W. H.; Cheung, Siu Tim; Siveke, Jens
    Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression
    In: Nature Communications Jg. 13 (2022) Nr. 1,
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Thielmann, Carl Maximilian; Matull, Johanna; Zaremba, Anne; Murali, Rajmohan; Chorti, Eleftheria; Lodde, Georg; Jansen, Philipp; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pföhler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Weichenthal, Michael; Kretz, Julia; Möller, Inga; Sucker, Antje; Paschen, Annette; Livingstone, Elisabeth; Zimmer, Lisa; Hadaschik, Eva; Ugurel, Selma; Schadendorf, Dirk; Griewank, Klaus G.
    TERT promoter mutations are associated with longer progression-free and overall survival in patients with BRAF-mutant melanoma receiving BRAF and MEK inhibitor therapy
    In: European Journal of Cancer (EJC) Jg. 161 (2022) S. 99 - 107
    ISSN: 1879-0852; 0959-8049; 1879-2995
    Online Volltext: dx.doi.org/
  • Strobel, Sophia B.; Machiraju, Devayani; Hülsmeyer, Ingrid; Becker, Jürgen; Paschen, Annette; Jäger, Dirk; Wels, Winfried S.; Bachmann, Michael; Hassel, Jessica C.
    Expression of potential targets for cell-based therapies on melanoma cells
    In: Life Jg. 11 (2021) Nr. 4, S. 269
    ISSN: 2075-1729
    Online Volltext: dx.doi.org/ (Open Access)
  • Jansen, Philipp; Müller, Hansgeorg; Lodde, Georg C.; Zaremba, Anne; Möller, Inga; Sucker, Antje; Paschen, Annette; Esser, Stefan; Schaller, Jörg; Gunzer, Matthias; Standl, Fabian; Bauer, Sebastian; Schadendorf, Dirk; Mentzel, Thomas; Hadaschik, Eva; Griewank, Klaus G.
    GNA14, GNA11, and GNAQ Mutations Are Frequent in Benign but Not Malignant Cutaneous Vascular Tumors
    In: Frontiers in Genetics Jg. 12 (2021)
    ISSN: 1664-8021
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Thier, Beatrice; Paschen, Annette
    Innate RIG-I signaling restores antigen presentation in tumors and overcomes T cell resistance
    In: Cell Stress: The Journal of the European Research Institute for Integrated Cellular Pathology Jg. 5 (2021) Nr. 2, S. 26 - 28
    ISSN: 2523-0204
    Online Volltext: dx.doi.org/ (Open Access)
  • Thier, Beatrice; Paschen, Annette
    Innate RIG-I signaling restores antigen presentation in tumors and overcomes T cell resistance
    In: Cell Stress: The Journal of the European Research Institute for Integrated Cellular Pathology Jg. 5 (2021) Nr. 2, S. 26 - 28
    ISSN: 2523-0204
    Online Volltext: dx.doi.org/ (Open Access)
  • Harbers, Franziska Noelle; Thier, Beatrice; Stupia, Simone; Zhu, Si; Schwamborn, Marion; Peller, Vicky; Chauvistré, Heike; Crivello, Pietro; Fleischhauer, Katharina; Rösch, Alexander; Sucker, Antje; Schadendorf, Dirk; Chen, Yong; Paschen, Annette; Zhao, Fang
    Melanoma Differentiation Trajectories Determine Sensitivity Toward Pre-Existing CD8⁺ Tumor-Infiltrating Lymphocytes
    In: Journal of Investigative Dermatology Jg. 141 (2021) Nr. 10, S. 2480 - 2489
    ISSN: 1523-1747; 0022-202X
    Online Volltext: dx.doi.org/ (Open Access)
  • Zaremba, Anne; Lodde, Georg; Murali, Rajmohan; Philip, Manuel; Cosgarea, Ioana; Jansen, Philipp; Chorti, Eleftheria; Rose, Christian; Hemmerlein, Bernhard; Matull, Johanna; Thielmann, Carl Maximilian; Kretz, Julia; Möller, Inga; Sucker, Antje; Paschen, Annette; Livingstone, Elisabeth; Zimmer, Lisa; Horn, Susanne; Schadendorf, Dirk; Hadaschik, Eva; Griewank, Klaus
    Molecular pathology as a diagnostic aid in difficult-to-classify melanocytic tumours with spitzoid morphology
    In: European Journal of Cancer Jg. 148 (2021) S. 340 - 347
    ISSN: 1879-0852; 0959-8049
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Thielmann, Carl Maximilian; Chorti, Eleftheria; Matull, Johanna; Murali, Rajmohan; Zaremba-Montenari, Anne; Lodde, Georg; Jansen, Philipp; Richter, Luisa; Kretz, Julia; Möller, Inga; Sucker, Antje; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pföhler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Weichenthal, Michael; Paschen, Annette; Livingstone, Elisabeth; Zimmer, Lisa; Schadendorf, Dirk; Hadaschik, Eva; Ugurel, Selma; Griewank, Klaus
    NF1-mutated melanomas reveal distinct clinical characteristics depending on tumour origin and respond favourably to immune checkpoint inhibitors
    In: European Journal of Cancer (EJC) Jg. 159 (2021) S. 113 - 124
    ISSN: 1879-0852; 0959-8049; 1879-2995
    Online Volltext: dx.doi.org/
  • Váraljai, Renáta; Elouali, S.; Lueong, Smiths S.; Wistuba-Hamprecht, Kilian; Seremet, Teofila C.; Siveke, Jens; Becker, Jürgen; Sucker, Antje; Paschen, Annette; Horn, Peter; Neyns, Bart; Weide, Benjamin M.; Schadendorf, Dirk; Rösch, Alexander
    The predictive and prognostic significance of cell-free DNA concentration in melanoma
    In: Journal of the European Academy of Dermatology and Venereology Jg. 35 (2021) Nr. 2, S. 387 - 395
    ISSN: 0926-9959; 1468-3083
    Online Volltext: dx.doi.org/ (Open Access)
  • Bhat, Hilal; Zaun, Gregor; Hamdan, Thamer A.; Lang, Judith; Adomati, Tom; Schmitz, Rosa; Friedrich, Sarah-Kim; Bergerhausen, Michael; Cham, Lamin B.; Li, Fanghui; Ali, Murtaza; Zhou, Fan; Khairnar, Vishal; Duhan, Vikas; Brandenburg, Tim; Machlah, Yara Maria; Schiller, Maximilian; Berry, Arshia; Xu, Haifeng; Vollmer, Jörg; Häussinger, Dieter; Thier, Beatrice; Pandyra, Aleksandra A.; Schadendorf, Dirk; Paschen, Annette; Schuler, Martin; Lang, Philipp A.; Lang, Karl S.
    Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression
    In: Frontiers in Immunology Jg. 11 (2020) S. 1849
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, David; Schilling, Bastian; Liu, Derek; Sucker, Antje; Livingstone, Elisabeth; Jerby-Arnon, Livnat; Zimmer, Lisa; Gutzmer, Ralf; Satzger, Imke; Loquai, Carmen; Grabbe, Stephan; Vokes, Natalie; Margolis, Claire A.; Conway, Jake; He, Meng Xiao; Elmarakeby, Haitham; Dietlein, Felix; Miao, Diana; Tracy, Adam; Gogas, Helen; Goldinger, Simone M.; Utikal, Jochen; Blank, Christian U.; Rauschenberg, Ricarda; von Bubnoff, Dagmar; Krackhardt, Angela; Weide, Benjamin; Haferkamp, Sebastian; Kiecker, Felix; Izar, Ben; Garraway, Levi; Regev, Aviv; Flaherty, Keith; Paschen, Annette; Van Allen, Eliezer M.; Schadendorf, Dirk
    Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
    In: Nature Medicine Jg. 26 (2020) Nr. 7, S. 1147
    ISSN: 1546-170X; 1078-8956
    Online Volltext: dx.doi.org/ (Open Access)
  • David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A.; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D.; Tenbusch, Matthias; Dietze, Kirsten; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S.; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid; Dittmer, Ulf; Zelinskyy, Gennadiy
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
    In: PLoS Pathogens Jg. 16 (2020) Nr. 3,
    ISSN: 1553-7374; 1553-7366
    Online Volltext: dx.doi.org/ (Open Access)
  • Textoris-Taube, Kathrin; Cammann, Clemens; Henklein, Petra; Topfstedt, Eylin; Ebstein, Frédéric; Henze, Sarah; Liepe, Juliane; Zhao, Fang; Schadendorf, Dirk; Dahlmann, Burkhardt; Uckert, Wolfgang; Paschen, Annette; Mishto, Michele; Seifert, Ulrike
    ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope
    In: European Journal of Immunology Jg. 50 (2020) Nr. 2, S. 270 - 283
    ISSN: 1521-4141; 0014-2980
    Online Volltext: dx.doi.org/ (Open Access)
  • Ugurel, Selma; Schadendorf, Dirk; Horny, K.; Sucker, Antje; Schramm, Sabine; Utikal, Jochen; Pföhler, Claudia; Herbst, Rudolf A.; Schilling, B.; Blank, Christian U.; Becker, Jürgen; Paschen, Annette; Zimmer, Lisa; Livingstone, Elisabeth; Horn, Peter; Rebmann, Vera
    Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma
    In: Annals of Oncology Jg. 31 (2020) Nr. 1, S. 144 - 152
    ISSN: 1569-8041; 0923-7534
    Online Volltext: dx.doi.org/ (Open Access)
  • Such, Lina; Zhao, Fang; Liu, Derek; Thier, Beatrice; Le-Trilling, Vu Thuy Khanh; Sucker, Antje; Coch, Christoph; Pieper, Natalia; Howe, Sebastian; Bhat, Hilal; Kalkavan, Halime; Ritter, Cathrin; Brinkhaus, Robin; Ugurel, Selma; Köster, Johannes; Seifert, Ulrike; Dittmer, Ulf; Schuler, Martin; Lang, Karl S.; Kufer, Thomas A.; Hartmann, Gunther; Becker, Jürgen; Horn, Susanne; Ferrone, Soldano; Liu, David; Van Allen, Eliezer M.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Paschen, Annette
    Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy
    In: The Journal of Clinical Investigation (JCI) Jg. 130 (2020) Nr. 8, S. 4266 - 4281
    ISSN: 1558-8238; 0021-9738
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Malyshkina, Anna; Littwitz-Salomon, Elisabeth; Sutter, Kathrin; Ross, Jean Alexander; Paschen, Annette; Windmann, Sonja; Schimmer, Simone; Dittmer, Ulf
    Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance
    In: Cancer Immunology, Immunotherapy Jg. 68 (2019) Nr. 3, S. 479 - 488
    ISSN: 1432-0851; 0340-7004
    Online Volltext: dx.doi.org/
  • Zaremba, Anne; Murali, Rajmohan; Jansen, Philipp; Möller, Inga; Sucker, Antje; Paschen, Annette; Zimmer, Lisa; Livingstone, Elisabeth; Brinker, Titus J.; Hadaschik, Eva; Franklin, Cindy; Rösch, Alexander; Ugurel, Selma; Schadendorf, Dirk; Griewank, Klaus; Cosgarea, Ioana
    Clinical and genetic analysis of melanomas arising in acral sites
    In: European Journal of Cancer Jg. 119 (2019) S. 66 - 76
    ISSN: 1879-0852; 0959-8049
    Online Volltext: dx.doi.org/ (Open Access)
  • Daßler-Plenker, Juliane; Paschen, Annette; Putschli, Bastian; Rattay, Stephanie; Schmitz, Saskia; Goldeck, Marion; Bartok, Eva; Hartmann, Gunther; Coch, Christoph
    Direct RIG-I activation in human NK cells induces TRAIL-dependent cytotoxicity toward autologous melanoma cells
    In: International Journal of Cancer Jg. 144 (2019) Nr. 7, S. 1645 - 1656
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/ (Open Access)
  • Schuldner, Maximiliane; Dörsam, Bastian; Shatnyeva, Olga; Reiners, Katrin S.; Kubarenko, Andriy; Hansen, Hinrich P.; Finkernagel, Florian; Roth, Katrin; Theurich, Sebastian; Nist, Andrea; Stiewe, Thorsten; Paschen, Annette; Knittel, Gero; Reinhardt, Hans C.; Müller, Rolf; Hallek, Michael; von Strandmann, Elke Pogge
    Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53
    In: Theranostics Jg. 9 (2019) Nr. 21, S. 6047 - 6062
    ISSN: 1838-7640
    Online Volltext: dx.doi.org/ (Open Access)
  • Jansen, Philipp; Cosgarea, Ioana; Murali, Rajmohan; Möller, Inga; Sucker, Antje; Franklin, Cindy; Paschen, Annette; Zaremba, Anne; Brinker, Titus Josef; Stoffels, Ingo; Schadendorf, Dirk; Klode, Joachim; Hadaschik, Eva; Griewank, Klaus
    Frequent Occurrence of NRAS and BRAF Mutations in Human Acral Naevi
    In: Cancers Jg. 11 (2019) Nr. 4, S. 546
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ugurel, Selma; Schadendorf, Dirk; Sucker, A.; Schramm, Sara; Utikal, J.; Pfohler, C.; Herbst, R.; Schilling, Bastian; Blank, C.; Becker, J. C.; Paschen, Annette; Zimmer, Lisa; Livingstone, Elisabeth; Horn, Peter; Rebmann, Vera
    High PD-1 or PD-L1 Concentrations in the Serum of Melanoma Patients are predictive for reduced Therapeutic Success of PD-1 Inhibition
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 17 (2019) Nr. Suppl. 5, S. 7 - 7
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
  • Liu, David; Schilling, Bastian; Liu, Derek; Sucker, Antje; Livingstone, Elisabeth; Jerby-Amon, Livnat; Zimmer, Lisa; Gutzmer, Ralf; Satzger, Imke; Loquai, Carmen; Grabbe, Stephan; Vokes, Natalie; Margolis, Claire A.; Conway, Jake; He, Meng Xiao; Elmarakeby, Haitham; Dietlein, Felix; Miao, Diana; Tracy, Adam; Gogas, Helen; Goldinger, Simone M.; Utikal, Jochen; Blank, Christian U.; Rauschenberg, Ricarda; Bubnoff, Dagmar von; Krackhardt, Angela; Weide, Benjamin; Haferkamp, Sebastian; Kiecker, Felix; Izar, Ben; Garraway, Levi; Regev, Aviv; Flaherty, Keith; Paschen, Annette; Allen, Eliezer M. van; Schadendorf, Dirk
    Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
    In: Nature Medicine Jg. 25 (2019) Nr. 12, S. 1916 - 1927
    ISSN: 1546-170X; 1078-8956
    Online Volltext: dx.doi.org/ (Open Access)
  • Phung, Bengt; Cieśla, Maciej; Sanna, Adriana; Guzzi, Nicola; Beneventi, Giulia; Cao Thi Ngoc, Phuong; Lauss, Martin; Cabrita, Rita; Cordero, Eugenia; Bosch, Ana; Rosengren, Frida; Häkkinen, Jari; Griewank, Klaus; Paschen, Annette; Harbst, Katja; Olsson, Håkan; Ingvar, Christian; Carneiro, Ana; Tsao, Hensin; Schadendorf, Dirk; Pietras, Kristian; Bellodi, Cristian; Jönsson, Göran
    The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
    In: Cell Reports Jg. 27 (2019) Nr. 12, S. 3573 - 3586.e7
    ISSN: 2211-1247
    Online Volltext: dx.doi.org/ (Open Access)
  • Pieper, Natalia; Zaremba, Anne; Leonardelli, Sonia; Harbers, Franziska Noelle; Schwamborn, Marion; Lübcke, Silke; Schrörs, Barbara; Baingo, Jolanthe; Schramm, Alexander; Haferkamp, Sebastian; Seifert, Ulrike; Sucker, Antje; Lennerz, Volker; Wölfel, Thomas; Schadendorf, Dirk; Schilling, Bastian; Paschen, Annette; Zhao, Fang
    Evolution of melanoma cross-resistance to CD8⁺ T cells and MAPK inhibition in the course of BRAFi treatment
    In: OncoImmunology Jg. 7 (2018) Nr. 8,
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • López-Cobo, Sheila; Campos-Silva, Carmen; Moyano, Amanda; Oliveira-Rodríguez, Myriam; Paschen, Annette; Yáñez-Mó, María; Blanco-López, María Carmen; Valés-Gómez, Mar
    Immunoassays for scarce tumour-antigens in exosomes : Detection of the human NKG2D-Ligand, MICA, in tetraspanin-containing nanovesicles from melanoma
    In: Journal of Nanobiotechnology Jg. 16 (2018) Nr. 1, S. 47
    ISSN: 1477-3155
    Online Volltext: dx.doi.org/ (Open Access)
  • López-Cobo, Sheila; Pieper, Natalia; Campos-Silva, Carmen; García-Cuesta, Eva M.; Reyburn, Hugh T.; Paschen, Annette; Valés-Gómez, Mar
    Impaired NK cell recognition of vemurafenib-treated melanoma cells is overcome by simultaneous application of histone deacetylase inhibitors
    In: OncoImmunology Jg. 7 (2018) Nr. 2,
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Scholz, S.L.; Cosgarea, I.; Süßkind, D.; Murali, R.; Möller, I.; Reis, Henning; Leonardelli, S.; Schilling, Bastian; Schimming, T.; Hadaschik, Eva; Franklin, Cindy; Paschen, Annette; Sucker, A.; Steuhl, Klaus-Peter; Schadendorf, Dirk; Westekemper, Henrike; Griewank, Klaus
    NF1 mutations in conjunctival melanoma
    In: British Journal of Cancer (BJC) Jg. 118 (2018) Nr. 9, S. 1243 - 1247
    ISSN: 1532-1827; 0007-0920
    Online Volltext: dx.doi.org/ (Open Access)
  • Horn, Susanne; Leonardelli, Sonia; Sucker, Antje; Schadendorf, Dirk; Griewank, Klaus; Paschen, Annette
    Tumor CDKN2A-Associated JAK2 Loss and Susceptibility to Immunotherapy Resistance
    In: Journal of the National Cancer Institute Jg. 110 (2018) Nr. 6, S. 677 - 681
    ISSN: 0198-0157; 0027-8874
    Online Volltext: dx.doi.org/ (Open Access)
  • Sucker, Antje; Zhao, Fang; Pieper, Natalia; Heeke, Christina; Maltaner, Raffaela; Stadtler, Nadine; Real, Birgit; Bielefeld, Nicola; Howe, Sebastian; Weide, Benjamin; Gutzmer, Ralf; Utikal, Jochen; Loquai, Carmen; Gogas, Helen; Klein-Hitpaß, Ludger; Zeschnigk, Michael; Westendorf, Astrid; Trilling, Mirko; Horn, Susanne; Schilling, Bastian; Schadendorf, Dirk; Griewank, Klaus; Paschen, Annette
    Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesions
    In: Nature Communications Jg. 8 (2017)
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Petri, Robert Michael; Hackel, Alexander; Hahnel, Katrin; Dumitru, Claudia Alexandra; Bruderek, Kirsten; Flohe, Stefanie; Paschen, Annette; Lang, Stephan; Brandau, Sven
    Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
    In: Stem Cell Reports Jg. 9 (2017) Nr. 3, S. 985 - 998
    ISSN: 2213-6711
    Online Volltext: dx.doi.org/ (Open Access)
  • Hackel, A. M.; Petri, Maximilian; Hahnel, K.; Dumitru, C. A.; Bruderek, K.; Flohe, Stefanie; Paschen, Annette; Lang, Stephan; Brandau, Sven
    Activated tissue-resident mesenchymal stromal cells regulate natural killer cell immune and tissue regenerative function
    In: European Journal of Immunology Jg. 47 (2017) Nr. S2, Special Issue:47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 62
    ISSN: 0014-2980
    Online Volltext: dx.doi.org/
  • Möller, Inga; Murali, Rajmohan; Müller, Hansgeorg; Wiesner, Thomas; Jackett, Louise A.; Scholz, Simone L.; Cosgarea, Ioana; van de Nes, Johannes; Sucker, Antje; Hillen, Uwe; Schilling, Bastian; Paschen, Annette; Kutzner, Heinz; Rütten, Arno; Böckers, Martin; Scolyer, Richard A.; Schadendorf, Dirk; Griewank, Klaus
    Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue nevi
    In: Modern Pathology Jg. 30 (2017) Nr. 3, S. 350 - 356
    ISSN: 1530-0285; 0893-3952
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ritter, Cathrin; Fan, Kaiji; Paschen, Annette; Reker Hardrup, Sine; Ferrone, Soldano; Nghiem, Paul; Ugurel, Selma; Schrama, David; Becker, Jürgen
    Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma
    In: Scientific Reports Jg. 7 (2017) Nr. 1, S. 2290
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Malyshkina, Anna; Littwitz-Salomon, Elisabeth; Sutter, Kathrin; Zelinskyy, Gennadiy; Windmann, Sonja; Schimmer, Simone; Paschen, Annette; Streeck, Hendrik; Hasenkrug, Kim J; Dittmer, Ulf
    Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection
    In: Scientific Reports Jg. 7 (2017) S. 7785
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Scholz, Simone L.; Möller, Inga; Reis, Henning; Süßkind, Daniela; van de Nes, Johannes; Leonardelli, Sonia; Schilling, Bastian; Livingstone, Elisabeth; Schimming, Tobias; Paschen, Annette; Sucker, Antje; Murali, Rajmohan; Steuhl, Klaus-Peter; Schadendorf, Dirk; Westekemper, Henrike; Griewank, Klaus
    Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma
    In: Investigative Ophthalmology & Visual Science, IOVS Jg. 58 (2017) Nr. 9, S. 3464 - 3470
    ISSN: 1552-5783; 0146-0404
    Online Volltext: dx.doi.org/ (Open Access)
  • Schrörs, Barbara; Lübcke, Silke; Lennerz, Volker; Fatho, Martina; Bicker, Anne; Wölfel, Catherine; Derigs, Patrick; Hankeln, Thomas; Schadendorf, Dirk; Paschen, Annette; Wölfel, Thomas
    HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model
    In: OncoTarget Jg. 8 (2017) Nr. 17, S. 28312 - 28327
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Griewank, Klaus; Müller, Hansgeorg; Jackett, Louise A.; Emberger, Michael; Möller, Inga; van de Nes, Johannes; Zimmer, Lisa; Livingstone, Elisabeth; Wiesner, Thomas; Scholz, Simone L.; Cosgarea, Ioana; Sucker, Antje; Schimming, Tobias; Hillen, Uwe; Schilling, Bastian; Paschen, Annette; Reis, Henning; Mentzel, Thomas; Kutzner, Heinz; Rütten, Arno; Murali, Rajmohan; Scolyer, Richard A.; Schadendorf, Dirk
    SF3B1 and BAP1 mutations in blue nevus-like melanoma
    In: Modern Pathology Jg. 30 (2017) Nr. 7, S. 928 - 939
    ISSN: 1530-0285; 0893-3952
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Maurus, K.; Hufnagel, A.; Geiger, F.; Graf, S.; Berking, C.; Heinemann, A.; Paschen, Annette; Kneitz, S.; Stigloher, C.; Geissinger, E.; Otto, C.; Bosserhoff, A.; Schartl, M.; Meierjohann, S.
    The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation
    In: Oncogene Jg. 36 (2017) Nr. 36, S. 5110 - 5121
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Oliveira-Rodríguez, Myriam; López-Cobo, Sheila; Reyburn, Hugh T; Costa-García, Agustín; López-Martín, Soraya; Yáñez-Mó, María; Cernuda-Morollón, Eva; Paschen, Annette; Valés-Gómez, Mar; Blanco-López, Maria Carmen
    Development of a rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluids
    In: Journal of Extracellular Vesicles (JEV) Jg. 5 (2016) Nr. 1, S. 31803
    ISSN: 2001-3078
    Online Volltext: dx.doi.org/ (Open Access)
  • Ebstein, Frédéric; Keller, Martin; Paschen, Annette; Walden, Peter; Seeger, Michael; Bürger, Elke; Krüger, Elke; Schadendorf, Dirk; Kloetzel, Peter-M; Seifert, Ulrike
    Exposure to Melan-A/MART-126-35 tumor epitope specific CD8(+)T cells reveals immune escape by affecting the ubiquitin-proteasome system (UPS)
    In: Scientific Reports Jg. 6 (2016) S. 25208
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhao, Fang; Sucker, Antje; Horn, Susanne; Heeke, Christina; Bielefeld, Nicola; Schrörs, Barbara; Bicker, Anne; Lindemann, Monika; Rösch, Alexander; Gaudernack, Gustav; Stiller, Mathias; Becker, Jürgen; Lennerz, Volker; Wölfel, Thomas; Schadendorf, Dirk; Griewank, Klaus; Paschen, Annette
    Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
    In: Cancer Research Jg. 76 (2016) Nr. 15, S. 4347 - 4358
    ISSN: 1538-7445; 0008-5472
    Online Volltext: dx.doi.org/
  • Rösch, Alexander; Paschen, Annette; Landsberg, Jenny; Helfrich, Iris; Becker, Jürgen; Schadendorf, Dirk
    Phenotypic tumour cell plasticity as a resistance mechanism and therapeutic target in melanoma
    In: European Journal of Cancer Jg. 59 (2016) S. 109 - 112
    ISSN: 0959-8049
    Online Volltext: dx.doi.org/
  • Kandilarova, Snezhina Mihailova; Paschen, Annette; Mihaylova, Anastassia; Ivanova, Milena; Schadendorf, Dirk; Naumova, Elissaveta
    The Influence of HLA and KIR Genes on Malignant Melanoma Development and Progression
    In: Archivum Immunologiae et Therapiae Experimentalis Jg. 64 (2016) Nr. Suppl. 1, S. 73 - 81
    ISSN: 0004-069X; 1661-4917
    Online Volltext: dx.doi.org/
  • Scholz, Simone L.; Horn, Susanne; Murali, Rajmohan; Möller, Inga; Sucker, Antje; Sondermann, Wiebke; Stiller, Mathias; Schilling, Bastian; Livingstone, Elisabeth; Zimmer, Lisa; Reis, Henning; Metz, Claudia H; Zeschnigk, Michael; Paschen, Annette; Steuhl, Klaus-Peter; Schadendorf, Dirk; Westekemper, Henrike; Griewank, Klaus
    Analysis of SDHD promoter mutations in various types of melanoma
    In: OncoTarget Jg. 6 (2015) Nr. 28, S. 25868 - 25882
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Scholz, S.; Horn, S.; Murali, R.; Moeller, I.; Sucker, A.; Sondermann, W.; Stiller, Mathias; Schilling, Bastian; Livingstone, Elisabeth; Zimmer, Lisa; Reis, Henning; Metz, C.; Zeschnigk, Michael; Paschen, Annette; Steuhl, Klaus-Peter; Schadendorf, Dirk; Westekemper, Henrike; Griewank, Klaus
    Analysis of SDHD promoter mutations in various types of melanoma
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 13 (2015) Nr. Suppl. 2, S. 11
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Sucker, Antje; Paschen, Annette
    Deciphering the genetic evolution of T-cell resistance in melanoma
    In: OncoImmunology Jg. 4 (2015) Nr. 5,
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/ (Open Access)
  • Scholz, Simone L; Thomasen, Henning; Reis, Henning; Möller, Inga; Darawsha, Raid; Müller, Bettina; Dekowski, Dirk; Sucker, Antje; Schilling, Bastian; Schadendorf, Dirk; Steuhl, Klaus-Peter; Paschen, Annette; Westekemper, Henrike; Meller, Daniel; Griewank, Klaus
    Frequent TERT Promoter Mutations in Ocular Surface Squamous Neoplasia
    In: Investigative Ophthalmology & Visual Science, IOVS Jg. 56 (2015) Nr. 10, S. 5854 - 5861
    ISSN: 1552-5783; 0146-0404
    Online Volltext: dx.doi.org/ (Open Access)
  • Keller, Martin; Ebstein, Frédéric; Bürger, Elke; Textoris-Taube, Kathrin; Gorny, Xenia; Urban, Sabrina; Zhao, Fang; Dannenberg, Tanja; Sucker, Antje; Keller, Christin; Saveanu, Loredana; Krüger, Elke; Rothkötter, Hermann Josef; Dahlmann, Burkhardt; Henklein, Petra; Voigt, Antje; Kuckelkorn, Ulrike; Paschen, Annette; Kloetzel, Peter Michael; Seifert, Ulrike
    The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35-specific T-cell recognition
    In: European Journal of Immunology Jg. 45 (2015) Nr. 12, S. 3257 - 3268
    ISSN: 0014-2980
    Online Volltext: dx.doi.org/ (Open Access)
  • Schilling, Bastian; Sondermann, W.; Zhao, F.; Griewank, Klaus; Livingstone, Elisabeth; Sucker, A.; Zelba, H.; Weide, B.; Trefzer, U.; Wilhelm, T.; Loquai, C.; Berking, C.; Hassel, J.; Kähler, K. C.; Utikal, J.; Al~ghazal, P.; Gutzmer, R.; Goldinger, S. M.; Zimmer, Lisa; Paschen, Annette; Hillen, Uwe; Schadendorf, Dirk
    Differential influence of vemurafenib and dabrafenib on patients' lymphocytes despite similar clinical efficacy in melanoma
    In: Annals of Oncology Jg. 25 (2014) Nr. 3, S. 747 - 753
    ISSN: 1569-8041
    Online Volltext: dx.doi.org/
  • Paschen, Annette; Baingo, Jolanthe; Schadendorf, Dirk
    Expression of stress ligands of the immunoreceptor NKG2D in melanoma : regulation and clinical significance
    In: European Journal of Cell Biology Jg. 93 (2014) Nr. 1-2, S. 49 - 54
    ISSN: 1618-1298; 0171-9335
    Online Volltext: dx.doi.org/
  • Sucker, Antje; Zhao, Fang; Real, Birgit; Heeke, Christina; Bielefeld, Nicola; Maßen, Stefan; Horn, Susanne; Moll, Iris; Maltaner, Raffaela; Horn, Peter; Schilling, Bastian; Sabbatino, Francesco; Lennerz, Volker; Kloor, Matthias; Ferrone, Soldano; Schadendorf, Dirk; Falk, Christine S; Griewank, Klaus; Paschen, Annette
    Genetic evolution of T-cell resistance in the course of melanoma progression
    In: Clinical Cancer Research Jg. 20 (2014) Nr. 24, S. 6593 - 6604
    ISSN: 1078-0432
    Online Volltext: dx.doi.org/
  • Schlecker, Eva; Fiegler, Nathalie; Arnold, Annette; Altevogt, Peter; Rose-John, Stefan; Moldenhauer, Gerhard; Sucker, Antje; Paschen, Annette; Pogge von Strandmann, Elke; Textor, Sonja; Cerwenka, Adelheid
    Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30
    In: Cancer Research Jg. 74 (2014) Nr. 13, S. 3429 - 3440
    ISSN: 1538-7445; 0008-5472
    Online Volltext: dx.doi.org/
  • Ugurel, Selma; Paschen, Annette; Becker, Jürgen
    Dacarbazine in melanoma: From a chemotherapeutic drug to an immunomodulating agent
    In: Journal of Investigative Dermatology Jg. 133 (2013) Nr. 2, S. 289 - 292
    ISSN: 1523-1747; 0022-202X
    Online Volltext: dx.doi.org/ (Open Access)
  • Schilling, Bastian; Paschen, Annette
    Immunological consequences of selective BRAF inhibitors in malignant melanoma : Neutralization of myeloid-derived suppressor cells
    In: OncoImmunology Jg. 2 (2013) Nr. 8,
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/ (Open Access)
  • Griewank, Klaus; Ugurel, Selma; Schadendorf, Dirk; Paschen, Annette
    New developments in biomarkers for melanoma
    In: Current Opinion in Oncology Jg. 25 (2013) Nr. 2, S. 145 - 151
    ISSN: 1040-8746; 1531-703X
    Online Volltext: dx.doi.org/
  • Simon-Keller, Katja; Paschen, Annette; Hombach, Andreas A.; Ströbel, Philipp; Coindre, Jean-Michel; Eichmüller, Stefan B.; Vincent, Angela; Gattenlöhner, Stefan; Hoppe, Florian; Leuschner, Ivo; Stegmaier, Sabine; Koscielniak, Ewa; Leverkus, Martin; Altieri, Dario C.; Abken, Hinrich; Marx, Alexander
    Survivin blockade sensitizes rhabdomyosarcoma cells for lysis by fetal acetylcholine receptor-redirected T cells
    In: American Journal of Pathology Jg. 182 (2013) Nr. 6, S. 2121 - 2131
    ISSN: 1525-2191; 0002-9440
    Online Volltext: dx.doi.org/
  • Weide, Benjamin; Schilling, Bastian; Paschen, Annette; Görgens, Andre; Sucker, Antje; Zhao, Fang; Giebel, Bernd; Griewank, Klaus; Schadendorf, Dirk
    Vemurafenib reverses immunosuppression by myeloid derived suppressor cells
    In: Cancer Research Jg. 73 (2013) Nr. 8 Suppl., S. 4714
    ISSN: 1538-7445; 0008-5472
    Online Volltext: dx.doi.org/
  • Schilling, Bastian; Sucker, Antje; Griewank, Klaus; Zhao, Fang; Weide, Benjamin; Görgens, André; Giebel, Bernd; Schadendorf, Dirk; Paschen, Annette
    Vemurafenib reverses immunosuppression by myeloid derived suppressor cells
    In: International Journal of Cancer Jg. 133 (2013) Nr. 7, S. 1653 - 1663
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Paschen, Annette; Schadendorf, Dirk; Schilling, Bastian
    Gegen den Hautkrebs : Forschung zur Überwindung immuntherapeutischer Hürden beim malignen Melanom
    In: Unikate: Berichte aus Forschung und Lehre (2012) Nr. 42: Translationale Krebsforschung: Auf dem Weg zu neuen Therapien, S. 32 - 41
    ISBN: 978-3-934359-42-0 ISSN: 0944-6060; 1869-3881
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bernal, Monica; Ruiz-Cabello, Francisco; Concha, Angel; Paschen, Annette; Garrido, Federico
    Implication of the β2-microglobulin gene in the generation of tumor escape phenotypes
    In: Cancer Immunology, Immunotherapy Jg. 61 (2012) Nr. 9, S. 1359 - 1371
    ISSN: 1432-0851; 0340-7004
    Online Volltext: dx.doi.org/
  • Urban, Sabrina; Textoris-Taube, Kathrin; Reimann, Barbara; Janek, Katharina; Dannenberg, Tanja; Ebstein, Frédéric; Seifert, Christin; Zhao, Fang; Kessler, Jan H.; Halenius, Anne; Henklein, Petra; Paschke, Julia; Cadel, Sandrine; Bernhard, Helga; Ossendorp, Ferry; Foulon, Thierry; Schadendorf, Dirk; Paschen, Annette; Seifert, Ulrike
    The efficiency of human cytomegalovirus pp65₄₉₅₋₅₀₃ CD8 ⁺T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases
    In: The Journal of Immunology (JI) Jg. 189 (2012) Nr. 2, S. 529 - 538
    ISSN: 1550-6606; 0022-1767; 1047-7381; 1048-3233
    Online Volltext: dx.doi.org/
  • Heinemann, Anja; Zhao, Fang; Pechlivanis, Sonali; Eberle, Jürgen; Steinle, Alexander; Diederichs, Sven; Schadendorf, Dirk; Paschen, Annette
    Tumor Suppressive MicroRNAs miR-34a/c Control Cancer Cell Expression of ULBP2, a Stress-Induced Ligand of the Natural Killer Cell Receptor NKG2D
    In: Cancer Research Jg. 72 (2012) Nr. 2, S. 460 - 471
    ISSN: 1538-7445; 0008-5472
    Online Volltext: dx.doi.org/
  • Heinemann, Anja; Paschen, Annette
    Tumor suppressors control ULBP2, an innate surface ligand of the lymphocyte immune receptor NKG2D
    In: OncoImmunology Jg. 1 (2012) Nr. 4, S. 535 - 536
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/
  • Kessler, Jan H.; Khan, Selina; Seifert, Ulrike; Le Gall, Sylvie; Chow, K Martin; Paschen, Annette; Bres-Vloemans, Sandra A.; De Ru, Arnoud; Van Montfoort, Nadine; Franken, Kees L. M. C.; Benckhuijsen, Willemien E.; Brooks, Jill M.; Van Hall, Thorbald; Ray, Kallol; Mulder, Arend; Doxiadis, Ilias I. N.; Van Swieten, Paul F.; Overkleeft, Hermen S.; Prat, Annik; Tomkinson, Birgitta; Neefjes, Jacques; Kloetzel, Peter M.; Rodgers, David W.; Hersh, Louis B.; Drijfhout, Jan W.; Van Veelen, Peter A.; Ossendorp, Ferry; Melief, Cornelis J. M.
    Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
    In: Nature Immunology Jg. 12 (2011) Nr. 1, S. 45 - 53
    ISSN: 1529-2908; 1529-2916
    Online Volltext: dx.doi.org/
  • Maleno, Isabel; Aptsiauri, Natalia; Cabrera, Teresa; Gallego, Aurelia; Paschen, Annette; López-Nevot, Miguel Angel; Garrido, Federico
    Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumors
    In: Immunogenetics Jg. 63 (2011) Nr. 2, S. 65 - 71
    ISSN: 1432-1211; 0093-7711
    Online Volltext: dx.doi.org/
  • Simon-Keller, Katja; Paschen, Annette; Eichmüller, Stefan B.; Gattenlöhner, Stefan; Barth, Stefan; Koscielniak, Ewa; Leuschner, Ivo; Stöbel, P.; Hombach, Andreas A.; Abken, Hinrich; Marx, Alexander H.
    Adoptive T-Zell-Therapie des Rhabdomyosarkoms
    In: Der Pathologe Jg. 31 (2010) Nr. SUPPL. 2, S. 215 - 220
    ISSN: 1432-1963; 0172-8113
    Online Volltext: dx.doi.org/
  • Müller, M.; Beck, I. M.; Gadesmann, J.; Karschuk, N.; Paschen, Annette; Proksch, E.; Djonov, V.; Reiss, K.; Sedlacek, R.
    MMP19 is upregulated during melanoma progression and increases invasion of melanoma cells
    In: Modern Pathology Jg. 23 (2010) Nr. 4, S. 511 - 521
    ISSN: 0893-3952; 1530-0285
    Online Volltext: dx.doi.org/
  • Eberle, J.; Spangler, B.; Becker, J. C.; Heinemann, S. H.; Klein, C. A.; Kunz, M.; Kuphal, S.; Langer, P.; Mauch, C.; Meierjohann, S.; Paschen, Annette; Schadendorf, Dirk; Schartl, M.; Schittek, B.; Schönherr, R.; Tüting, T.; Zigrino, P.; Bosserhoff, A. K.
    Multicentre study on standardisation of melanoma cell culture : An initiative of the German Melanoma Research Network
    In: Pigment Cell and Melanoma Research Jg. 23 (2010) Nr. 2, S. 296 - 298
    ISSN: 1755-1471; 1755-148X
    Online Volltext: dx.doi.org/
  • Osen, W.; Soltek, S.; Song, M.; Leuchs, B.; Steitz, J.; Tüting, T.; Eichmüller, S. B.; Nguyen, X. D.; Schadendorf, Dirk; Paschen, Annette
    Screening of Human Tumor Antigens for CD4+ T Cell Epitopes by Combination of HLA-Transgenic Mice, Recombinant Adenovirus and Antigen Peptide Libraries
    In: PLoS ONE Jg. 5 (2010) Nr. 11, S. e14137
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Placke, Jan-Malte; Bottek, J.; Váraljai, R.; Shannan, B.; Krisp, C.; Spangenberg, P.; Soun, C.; Hoffmann, F.; Zhao, F.; Paschen, Annette; Schlüter, H.; von Eggeling, F.; Helfrich, Iris; Rambow, F.; Schadendorf, Dirk; Engel, Daniel Robert; Rösch, Alexander;
    Compartment-based proteomics of CD8high vs. CD8low melanoma regions reveals differential regulation of TOR signaling
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. S3, S. 12
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Zaremba, Anne; Jansen, Philipp; Murali, R.; Mayakonda, A.; Riedel, A.; Krahl, D.; Burkhardt, H.; John, S.; Géraud, C.; Philip, M.; Kretz, J.; Möller, I.; Stadtler, N.; Sucker, A.; Paschen, Annette; Ugurel, Selma; Zimmer, Lisa; Livingstone, Elisabeth; Horn, S.; Plass, C.; Schadendorf, Dirk; Hadaschik, Eva; Lutsik, P.; Griewank, Klaus;
    Genetic and methylation analysis of CTNNB1 mutations in benign and malignant melanocytic lesions
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. S3, S. 84
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Albrecht, L. J.; Höwner, A.; Griewank, Klaus; Lueong, S. S.; von Neuhoff, N.; Horn, Peter A.; Sucker, A.; Paschen, Annette; Livingstone, Elisabeth; Ugurel, Selma; Zimmer, Lisa; Horn, S.; Siveke, Jens T.; Schadendorf, Dirk; Váraljai, R.; Rösch, Alexander;
    Im Plasma zirkulierende zellfreie mRNA ermöglicht die minimal-invasive und Genotyp-unabhängige Therapieüberwachung bei Patienten mit Melanom
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. S3, S. 12 - 13
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Navarro Ocon, Alba; Cabo Zabala, Laura; Brinkmann, Berit; Lopez Sanchez, Alberto; Paschen, Annette; Garrido, Federico; Ruiz Cabello, Francisco; Aptsiauri, Natalia;
    Liquid biopsy for the detection of HLA-I alterations in cancer
    Joint 35th European Immunogenetics and Histocompatibility Conference; May 17–20, 2022; Amsterdam, the Netherlands,
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 99 (2022) Nr. 5, SI, S. 430
    ISSN: 2059-2310; 2059-2302
  • Jansen, P.; Zaremba, Anne; Philip, M.; Lodde, Georg; Livingstone, Elisabeth; Zimmer, Lisa; Ugurel, Selma; Paschen, Annette; Sucker, A.; Möller, I.; Landsberg, J.; Rose, C.; Emberger, M.; Schaller, J.; Plass, C.; Hadaschik, Eva; Schadendorf, Dirk; Mentzel, T.; Lutsik, P.; Griewank, Klaus;
    Molekularpathologie und Methylierungsprofile als diagnostische Unterstützung zur Differenzierung von Klarzellsarkomen und melanozytären Tumoren
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. S3, S. 88
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Chauvistre, H.; Shannan, B.; Daignault-Mill, S. M.; Ju, R. J.; Picard, D.; Egetemaier, S.; Váraljai, R.; Gibhardt, C. S.; Keminer, O.; Horn, S.; Remke, M.; Paschen, Annette; Becker, Jürgen C.; Helfrich, Iris; Gul, S.; Herlyn, M.; Bogeski, I.; Rodríguez-López, J. N.; Haass, N. K.; Schadendorf, Dirk; Rösch, Alexander;
    Persister state-directed transitioning and vulnerability in melanoma
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 20 (2022) Nr. S3, S. 35 - 36
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Thier, B.; Such, L.; Peller, V.; Schwamborn, M.; Sucker, A.; Coch, C.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Zhao, F.; Paschen, Annette;
    Interferon-independent enhancement of melanoma cell immunogenicity by RIG-I activation
    47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF) Virtual, March 04‐06, 2021,
    In: Experimental Dermatology Jg. 30 (2021) Nr. 3, S. E78
    ISSN: 1600-0625; 0906-6705
  • Thier, B.; Zhao, F.; Horn, S.; Coch, C.; Hartmann, G.; Schadendorf, Dirk; Paschen, Annette
    Intratumoral Immunotherapy : RIG-I Agonists induce a dedifferentiated yet T-Cell-sensitive Melanoma Cell Phantotype
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 34
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
  • Zhao, F.; Peller, V.; Schwamborn, M.; Kwapik, S.; Sucker, A.; Ugurel, Selma; Schadendorf, Dirk; Paschen, Annette;
    Profiling of tumor-infiltrating T cells for guidance of melanoma salvage therapy in immune-checkpoint-blockade resistant patients
    47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF) Virtual, March 04‐06, 2021,
    In: Experimental Dermatology Jg. 30 (2021) Nr. 3, S. E52
    ISSN: 1600-0625; 0906-6705
    Online Volltext: dx.doi.org/
  • Thielmann, Carl Maximilian; Matull, J.; Zaremba, Anne; Chorti, E.; Lodde, Georg; Jansen, Philipp; Kretz, J.; Möller, I.; Sucker, A.; Paschen, Annette; Livingstone, Elisabeth; Zimmer, Lisa; Hadaschik, Eva; Ugurel, Selma; Schadendorf, Dirk; Griewank, Klaus
    TERT Promoter Mutations associated with longer progression-free and Overall Survival under BRAF/MEK Therapy
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 19 (2021) Nr. Suppl. 4, S. 31
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
  • Zhao, F.; Harbers, Franziska; Thier, Beatrice; Stupia, Simone; Zhu, S.; Schwamborn, Marion; Peller, Vladimir; Chauvistre, Heike; Rösch, Alexander; Sucker, Antje; Schadendorf, Dirk; Paschen, Annette
    Distinct melanoma differentiation trajectories driven by MAPKi associate with activation of CD8+tumor-infiltrating lymphocytes
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV17
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Thier, B.; Such, L.; Schwamborn, M.; Sucker, A.; Coch, C.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Zhao, F.; Paschen, Annette
    RIG-I activation enhances melanoma immunogenicity and improves anti-tumor T cell responses in combination with anti-PD-1 immune checkpoint blocking antibodies
    In: Journal for ImmunoTherapy of Cancer Jg. 8 (2020) Nr. Suppl. 2, S. A3
    ISSN: 2051-1426
    Online Volltext: dx.doi.org/ (Open Access)
  • Thier, Beatrice; Such, Lina; Sucker, Antje; Coch, Carla; Hartmann, G.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Zhao, F.; Paschen, Annette
    Tumorzell‐intrinsiche Aktivierung des Immunrezeptors RIG‐I in Kombination mit Immun‐Checkpoint‐Blockade verbessert anti‐Tumor T‐Zellantworten
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV18
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/
  • Haupert, V.; Fatho, M.; Kulka, K.; Wölfel, C.; Paschen, Annette; Wehler, D.; Theobald, M.; Lennerz, V.; Wölfel, T.;
    Impact of T cells transduced with an HLA-independent T-cell receptor (TCR) against the alpha chain of the GM-CSF receptor (CSF2RA) on hematopoietic progenitor cells
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Suppl. 4, S. 99
    ISSN: 2296-5262; 2296-5270; 1423-0240; 0378-584X
    Online Volltext: dx.doi.org/ (Open Access)
  • Pieper, N.; Zaremba, Anne; Harbers, F. N.; Schwamborn, M.; Lübcke, S.; Schrörs, B.; Sucker, A.; Lennerz, V.; Wölfel, T.; Schadendorf, Dirk; Paschen, Annette; Zhao, F.;
    Evolution of cross‐resistance to CD8+ T cells in the course of BRAF and MEK inhibitor treatment in BRAFV600E melanoma
    28. Deutschen Hautkrebskongresses (ADO‐Jahrestagung); 13.–15. September 2018; Stuttgart,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 16 (2018) Nr. 6, S. 53
    ISSN: 1610-0387; 1563-2571; 1610-0379; 0301-0481
    Online Volltext: dx.doi.org/ (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Paschen, Annette; Schadendorf, Dirk
    The era of checkpoint inhibition : Lessons learned from melanoma
    In: Current Immunotherapeutic Strategies in Cancer / Theobald, Matthias (Hrsg.) 2020, S. 169 - 187
    ISBN: 978-3-030-23764-6; 978-3-030-23765-3
    Online Volltext: dx.doi.org/

    • Forschungsberichte

  • Chauvistré, Heike; Daignault, Sheena M.; Shannan, Batool; Ju, Robert J.; Picard, Daniel; Vogel, Felix C. E.; Egetemaier, Stefanie; Krepler, Clemens; Rebecca, Vito W.; Sechi, Antonio; Kaschani, Farnusch; Keminer, Oliver; Stehbens, Samantha J.; Váraljai, Renáta; Ninck, Sabrina; Liu, Qin; Yin, Xiangfan; Jeyakumar, Kirujan; Xiao, Min; Löffek, Stefanie; Kubat, Linda; Spassova, Ivelina; Gul, Sheraz; Rahmann, Sven; Horn, Susanne; Ehrmann, Michael; Paschen, Annette; Becker, Jürgen; Helfrich, Iris; Rauh, Daniel; Kaiser, Markus; Remke, Marc; Herlyn, Meenhard; Haass, Nikolas K.; Schadendorf, Dirk; Rösch, Alexander
    The Janus-faced role of KDM5B heterogeneity in melanoma : Differentiation as a situational driver of both growth arrest and drug-resistance
    (2020) 50 Seiten
    Online Volltext: dx.doi.org/ (Open Access)