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Dipl.-Biologin / Dipl.-Informatikerin Bettina Budeus

Biologie / ZMB / AG Bioinformatik

Anschrift
Universitätsstr. 2-5
45141 Essen
Raum
S03 S03 A44
Telefon
+49 201 183 3781
Telefax
+49 201 183 3437
E-Mail
bettina.budeus@stud.uni-due.de

Funktionen

  • Doktorand/in, Bioinformatik and Computational Biophysics

Aktuelle Veranstaltungen

Keine aktuellen Veranstaltungen.

Vergangene Veranstaltungen (max. 10)

Keine vergangenen Veranstaltungen.

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Berg, Victoria; Lollies, Anna; Schneider, Markus; Johansson, Patricia; Weniger, Marc A.; Albertini, Emma; Facchetti, Fabio; Ascani, Stefano; Moawia, Abubakar; Bens, Susanne; Fischer, Anja; Siebert, Reiner; Klapper, Wolfram; Lorenzi, Luisa; Tiacci, Enrico; Hartmann, Sylvia; Budeus, Bettina; Hansmann, Martin-Leo; Küppers, Ralf
    Common origin and somatic mutation patterns of composite lymphomas and leukemias
    In: Leukemia 2025 , in press
    DOI (Open Access)
  • Berg, F.; Köper, E.; Limberg, A.S.; Mattonet, K.; Budeus, Bettina; Kumsta, R.; Hummel, E.M.; Moser, D.A.
    Development and validation of a novel cell type estimation method for targeted bisulfite sequencing data
    In: Epigenomics , Jg. 17 2025, Nr. 6, S. 389 – 396
    DOI (Open Access)
  • Dubler, Simon; Etringer, Michael; Lichtenstern, Christoph; Brenner, Thorsten; Zimmermann, Stefan; Schnitzler, Paul; Budeus, Bettina; Rengier, Fabian; Kalinowska, Paulina; Hoo, Yuan Lih; Weigand, Markus A.
    Implications for the diagnosis of aspiration and aspergillosis in critically ill patients with detection of galactomannan in broncho-alveolar lavage fluids
    In: Scientific Reports , Jg. 15 2025, Nr. 1, 1997
    DOI (Open Access)
  • Dampmann, Maria; Kibler, Artur; von Tresckow, Julia; Reinhardt, Hans Christian; Küppers, Ralf; Budeus, Bettina
    Single-cell analysis of a bi-clonal chronic lymphocytic leukemia reveals two clones with distinct gene expression pattern
    In: Leukemia and Lymphoma , Jg. 66 2025, Nr. 4, S. 744 – 752
    DOI (Open Access)
  • Szlachetko, Jagoda Agnieszka; Hofmann-Vega, Francisca; Budeus, Bettina; Schröder, Lara-Jasmin; Dumitru, Claudia Alexandra; Schmidt, Mathias; Deuss, Eric; Vollmer, Sebastian; Hanschmann, Eva-Maria; Busch, Maike; Kehrmann, Jan; Lang, Stephan; Dünker, Nicole; Hussain, Timon; Brandau, Sven
    Tumor cells that resist neutrophil anticancer cytotoxicity acquire a prometastatic and innate immune escape phenotype
    In: Cellular & Molecular Immunology , Jg. 22 2025, Nr. 5, S. 527 – 540
    DOI (Open Access)
  • Budeus, Bettina; Álvaro-Benito, Miguel; Crivello, Pietro
    HLA-DM and HLA-DO interplay for the peptide editing of HLA class II in healthy tissues and leukemia
    In: Best Practice & Research Clinical Haematology , Jg. 37 2024, Nr. 2, 101561
    DOI (Open Access)
  • Dr., Alefeld,; Haase, André; Van Meenen, Dario; Budeus, Bettina; Dräger, Oliver; Miroschnikov, Natalia; Ting, Saskia; Kanber, Deniz; Biewald, Eva; Bechrakis, Nikolaos; Dünker, Nicole; Busch, Maike
    In vitro model of retinoblastoma derived tumor and stromal cells for tumor microenvironment (TME) studies
    In: Cell Death and Disease , Jg. 15 2024, Nr. 12, 905
    DOI (Open Access)
  • Budeus, Bettina; Kroepel, Chiara; Stasch, Lisa Marie; Klein, Diana
    Matrix-free human lung organoids derived from induced pluripotent stem cells to model lung injury
    In: Stem Cell Research & Therapy , Jg. 15 2024, Nr. 1, 468
    DOI (Open Access)
  • Sentek, Hanna; Braun, Annika; Budeus, Bettina; Klein, Diana
    Non-small cell lung cancer cells and concomitant cancer therapy induce a resistance-promoting phenotype of tumor-associated mesenchymal stem cells
    In: Frontiers in Oncology , Jg. 14 2024, 1406268
    DOI, Online Volltext (Open Access)
  • Kibler, Artur; Seifert, Marc; Budeus, Bettina
    Age-related changes of the human splenic marginal zone B cell compartment
    In: Immunology Letters , Jg. 256-257 2023, S. 59 – 65
    DOI
  • Küppers, Ralf; Budeus, Bettina; Hartmann, Sylvia; Hansmann, Martin-Leo
    Clonal composition and differentiation stage of human CD30⁺ B cells in reactive lymph nodes
    In: Frontiers in Immunology , Jg. 14 2023, 1208610
    DOI, Online Volltext (Open Access)
  • Budeus, Bettina; Unger, Kristian; Hess, Julia; Sentek, Hanna; Klein, Diana
    Comparative computational analysis to distinguish mesenchymal stem cells from fibroblasts
    In: Frontiers in Immunology , Jg. 14 2023, 1270493
    DOI, Online Volltext (Open Access)
  • Zec, Kristina; Thiebes, Stephanie; Bottek, Jenny; Siemes, Devon; Spangenberg, Philippa; Trieu, Duc Viet; Kirstein, Nils; Subramaniam, Nirojah; Christ, Robin; Klein, Diana; Jendrossek, Verena; Loose, Maria; Wagenlehner, Florian; Jablonska, Jadwiga; Bracht, Thilo; Sitek, Barbara; Budeus, Bettina; Klein-Hitpaß, Ludger; Theegarten, Dirk; Shevchuk, Olga; Engel, Daniel Robert
    Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection
    In: Frontiers in Immunology , Jg. 14 2023, 1227191
    DOI, Online Volltext (Open Access)
  • Kronimus, Yannick; Albus, Alexandra; Hasenberg, Mike; Walkenfort, Bernd; Seifert, Marc; Budeus, Bettina; Gronewold, Janine; Hermann, Dirk M.; Ross, J. Alexander; Lochnit, Günter; Galuska, Sebastian P.; Marcus, Katrin; Sitek, Barbara; Klotsche, Jens; Mengel, David; Neumann, Sascha; Dodel, Richard
    Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's disease
    In: Alzheimer's & Dementia , Jg. 19 2023, Nr. 12, S. 5563 – 5572
    DOI (Open Access)
  • Budeus, Bettina; Kibler, Artur; Küppers, Ralf
    Human IgM–expressing memory B cells
    In: Frontiers in Immunology , Jg. 14 2023, 1308378
    DOI, Online Volltext (Open Access)
  • Dubler, Simon; Etringer, Michael; Weigand, Markus A.; Brenner, Thorsten; Zimmermann, Stefan; Schnitzler, Paul; Budeus, Bettina; Rengier, Fabian; Kalinowska, Paulina; Hoo, Yuan Lih; Lichtenstern, Christoph
    Impact of Invasive Pulmonary Aspergillosis in Critically Ill Surgical Patients with or without Solid Organ Transplantation
    In: Journal of Clinical Medicine (JCM) , Jg. 12 2023, Nr. 9, 3282
    DOI, Online Volltext (Open Access)
  • Röder, Bettina; Fahnenstiel, Hannah; Schäfer, Simon; Budeus, Bettina; Dampmann, Maria; Eichhorn, Melanie; Angermüller, Sieglinde; Brost, Claudia; Winkler, Thomas H; Seifert, Marc; Nitschke, Lars
    The inhibitory receptor Siglec-G controls the severity of chronic lymphocytic leukemia
    In: EMBO Reports , Jg. 24 2023, Nr. 8, e56420
    DOI (Open Access)
  • Miroschnikov, Natalia; Dräger, Oliver; Van Meenen, Dario; Metz, Klaus; Budeus, Bettina; Dünker, Nicole; Busch, Maike
    Tumor Suppressor Role of INPP4B in Chemoresistant Retinoblastoma
    In: Journal of Oncology 2023, 2270097
    DOI, Online Volltext (Open Access)
  • Antoni, Anne-Charlotte; Pylaeva, Ekaterina; Budeus, Bettina; Jablonska, Jadwiga; Klein-Hitpaß, Ludger; Dudda, Marcel; Flohé, Stefanie B.
    TLR2-induced CD8⁺ T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsis
    In: Frontiers in Immunology , Jg. 13 2022, 945409
    DOI (Open Access)
  • Kibler, Artur; Budeus, Bettina; Küppers, Ralf; Seifert, Marc
    The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells
    In: Frontiers in Immunology , Jg. 13 2022, 825619
    DOI, Online Volltext (Open Access)
  • Weiß, Annika L.; Meijer, Mandy; Budeus, Bettina; Pauper, Marc; Hakobjan, Marina; Groothuismink, Johanne; Shi, Yan; Neveling, Kornelia; Buitelaar, Jan K.; Hoogman, Martine; Franke, Barbara; Klein, Marieke
    DNA methylation associated with persistent ADHD suggests TARBP1 as novel candidate
    In: Neuropharmacology , Jg. 184 2021, S. 108370
    DOI (Open Access)
  • Budeus, Bettina; Kibler, Artur; Brauser, Martina; Homp, Ekaterina; Bronischewski, Kevin; Ross, J. Alexander; Görgens, Andre; Weniger, Marc; Dunst, Josefine; Kreslavsky, Taras; da Conceição Castro, Symone Vitoriano; Murke, Florian; Oakes, Christopher C.; Rusch, Peter; Andrikos, Dimitrios; Kern, Peter; Köninger, Angela; Lindemann, Monika; Johansson, Patricia; Hansen, Wiebke; Lundell, Anna-Carin; Rudin, Anna; Dürig, Jan; Giebel, Bernd; Hoffmann, Daniel; Küppers, Ralf; Seifert, Marc
    Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamics
    In: The Journal of Immunology (JI) , Jg. 206 2021, Nr. 12, S. 2839 – 2851
    DOI (Open Access)
  • Kibler, Artur; Budeus, Bettina; Homp, Ekaterina; Bronischewski, Kevin; Berg, Victoria; Sellmann, Ludger; Murke, Florian; Heinold, Andreas; Heinemann, Falko M.; Lindemann, Monika; Bekeredjian-Ding, Isabelle; Horn, Peter; Kirschning, Carsten Jürgen; Küppers, Ralf; Seifert, Marc
    Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life
    In: Journal of Experimental Medicine (JEM) , Jg. 218 2021, Nr. 4, S. e20201952
    DOI (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Budeus, Bettina; Kuhn, Matthias; Lauber, Chris; Seifert, Michael; Roeder, Ingo; Pförtner, Roman; Stuschke, Martin; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencing
    In: Cancers , Jg. 12 2020, Nr. 4, 986
    DOI, Online Volltext (Open Access)
  • Karimzadeh, Hadi; Kiraithe, Muthamia M.; Oberhardt, Valerie; Salimi Alizei, Elahe; Bockmann, Jan; Schulze zur Wiesch, Julian; Budeus, Bettina; Hoffmann, Daniel; Wedemeyer, Heiner; Cornberg, Markus; Krawczyk, Adalbert; Rashidi-Alavijeh, Jassin; Rodríguez-Frías, Francisco; Casillas, Rosario; Buti, Maria; Smedile, Antonina; Alavian, Seyed Moayed; Heinold, Andreas; Emmerich, Florian; Panning, Marcus; Gostick, Emma; Price, David A.; Timm, Jörg; Hofmann, Maike; Raziorrouh, Bijan; Thimme, Robert; Protzer, Ulrike; Roggendorf, Michael; Neumann-Haefelin, Christoph
    Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population Level
    In: Gastroenterology , Jg. 156 2019, Nr. 6, S. 1820 – 1833
    DOI (Open Access)
  • Alavian, Seyed Moayed; Price, David A.; Panning, Marcus; Neumann-Haefelin, Christoph; Bockmann, Jan; Wiesch, Julian Schulze zur; Wedemeyer, Heiner; Heinold, Andreas; Alizei, Elahe Salimi; Timm, Jörg; Casillas, Rosario; Protzer, Ulrike; Raziorrouh, Bijan; Smedile, Antonina; Rodríguez-Frías, Francisco; Hoffmann, Daniel; Oberhardt, Valerie; Buti, Maria; Thimme, Robert; Roggendorf, Michael; Hofmann, Maike; Gostick, Emma; Budeus, Bettina; Emmerich, Florian; Kiraithe, Muthamia M.; Karimzadeh, Hadi
    Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDV
    In: Journal of Hepatology , Jg. 70 2019, Nr. Suppl. 1, S. e21
    DOI
  • Karimzadeh, Hadi; Kiraithe, Muthamia M.; Kosinska, Anna D.; Glaser, Manuel; Fiedler, Melanie; Oberhardt, Valerie; Alizei, Elahe Salimi; Hofmann, Maike; Mok, Juk Yee; Nguyen, Melanie; van Esch, Wim J.E.; Budeus, Bettina; Grabowski, Jan; Homs, Maria; Olivero, Antonella; Keyvani, Hossein; Rodríguez-Frías, Francisco; Tabernero, David; Buti, Maria; Heinold, Andreas; Alavian, Seyed Moayed; Bauer, Tanja; Wiesch, Julian Schulze zur; Raziorrouh, Bijan; Hoffmann, Daniel; Smedile, Antonina; Rizzetto, Mario; Wedemeyer, Heiner; Timm, Jörg; Antes, Iris; Neumann-Haefelin, Christoph; Protzer, Ulrike; Roggendorf, Michael
    Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cells
    In: Journal of Virology , Jg. 92 2018, Nr. 13, e01891-17
    DOI (Open Access)
  • Saeedghalati, Mohammadkarim; Farahpour, Farnoush; Budeus, Bettina; Lange, Anja; Westendorf, Astrid; Seifert, Marc; Küppers, Ralf; Hoffmann, Daniel
    Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to Microbiomes
    In: PLoS Computational Biology , Jg. 13 2017, Nr. 1, e1005362
    DOI (Open Access)
  • Riemenschneider, Mona; Heider, Dominik; Gorry, Paul R.; Kaiser, Rolf; Bayanolhagh, Saeed; Shirvani-Dastgerdi, Elham; Sierra, Saleta; Budeus, Bettina; Cash, Kieran Y.
    Genotypic Prediction of Co-receptor Tropism of HIV-1 Subtypes A and C
    In: Scientific Reports , Jg. 6 2016, S. 24883
    DOI (Open Access)
  • Budeus, Bettina; Timm, Jörg; Hoffmann, Daniel
    SeqFeatR for the Discovery of Feature-Sequence Associations
    In: PLoS ONE , Jg. 11 2016, Nr. 1, S. e0146409
    DOI (Open Access)
  • Kefalakes, Helenie; Budeus, Bettina; Walker, Andreas; Jochum, Christoph; Hilgard, Gudrun; Heinold, Andreas; Heinemann, Falko M.; Gerken, Guido; Hoffmann, Daniel; Timm, Jörg
    Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection Pressure
    In: Hepatology , Jg. 62 2015, Nr. 1, S. 47 – 56
    DOI (Open Access)
  • Lange, Anja; Jost, Steffen Oliver; Heider, Dominik; Bock, Christina; Budeus, Bettina; Schilling, Elmar; Strittmatter, Axel; Boenigk, Jens; Hoffmann, Daniel
    AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communities
    In: PLoS ONE , Jg. 10 2015, Nr. 11, S. e0141590
    DOI (Open Access)
  • Budeus, Bettina; De Reynoso, Stefanie Schweigle; Przekopowitz, Martina; Hoffmann, Daniel; Seifert, Marc; Küppers, Ralf
    Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 112 2015, Nr. 38, S. E5281 – E5289
    DOI (Open Access)
  • Dang, S.; Wang, Yan; Budeus, Bettina; Verheyen, Jens; Yang, R.; Hoffmann, Daniel
    Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'
    In: Virologica Sinica , Jg. 29 2014, Nr. 1, S. 40 – 47
    DOI
  • Skibbe, K.; Budeus, Bettina; Heinemann, Falko M.; Timmer, L.; Horn, Peter; van Esch, W.; Hoffmann, Daniel; Siemann, H.; Scherbaum, Norbert; Timm, Jörg
    HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopes
    In: Journal of Hepatology , Jg. 60 2014, Nr. Suppl. 1, S. 140
    DOI
  • Qin, Bo; Budeus, Bettina; Cao, Liang; Wu, Chunchen; Wang, Yun; Zhang, Xiaoyong; Rayner, Simon; Hoffmann, Daniel; Lu, Mengji; Chen, Xinwen
    The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    In: Antiviral Research , Jg. 97 2013, Nr. 2, S. 93 – 100
    DOI

    • Abstracts

  • Fitzgerald, Donnacha; Roider, Tobias; Baertsch, Marc-A.; Vöhringer, Harald; Knoll, Mareike; Budeus, Bettina; Kibler, Artur; Mathioudaki, Anna; Caillé, Léandra; Li, Linsha; Mammen, Johannes; Seifert, Marc; Huber, Wolfgang; Dietrich, Sascha
    Single-Cell Multi-Omic and Spatial Analysis of Nodal B Cell Non-Hodgkin Lymphomas Reveals Plasticity in B Cell Maturation As a Driver of Intratumor Heterogeneity
    In: Blood , Jg. 140 2022, Nr. Supplement 1: 64th ASH Annual Meeting and Exposition, 10-13 December 2022, New Orleans, S. 752 – 753
    DOI (Open Access)
  • Karimzadeh, H.; Budeus, Bettina; Kosinska, A.; Bauer, T.; Heinold, Andreas; Hoffmann, D.; Protzer, U.; Roggendorf, Michael
    Correlation of Mutations within HDV-Protein with HLA Backgrounds of Patients Leads to Identification of Novel CD8 T Cell Epitopes
    In: Journal of Hepatology , Jg. 64 2016, Nr. 2, Suppl., S. S361
    DOI
  • Seifert, Marc; Przekopowitz, Martina; Schweigle, Stefanie; Budeus, Bettina; Taudien, Sarah; Lollies, Anna; Ronge, Viola; Sellmann, Ludger; Hillen, Uwe; Engler, Harald; Schedlowski, Manfred; Singer, Bernhard B.; Hoffmann, Daniel; Küppers, Ralf
    Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B Cells
    In: Scandinavian Journal of Immunology , Jg. 80 2014, Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233
    DOI

    • Beiträge in Sammelwerken und Tagungsbänden

  • Schnormeier, Ann-Kathrin; Budeus, Bettina
    Single Cell VDJ Sequencing of Normal and Malignant B and T Cells
    In: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.) 2025, S. 295 – 346
    DOI

    • Dissertation

  • Budeus, Bettina
    Statistical analysis of sequence populations in virology and immunology
    Duisburg, Essen 2017
    Online Volltext

    • Poster / Posterbeiträge

  • Jehn, L; Berg, V; Kibler, Artur; Boerner, E; Wälscher, J; Budeus, Bettina; Seifert, M; Taube, Christian; Bonella, Francesco
    Die durchflusszytometrische Untersuchung von T-Lymphozytensubpopulationen in der Ganzlungen-Lavage (GLL) bei der pulmonalen Alveolarproteinose : eine Pilot-Studie
    64. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin, 20.–23.03.2024, Mannheim, Germany,
    In: Pneumologie , Jg. 78 2024, Nr. Suppl. 1, S. S11 – S12
    DOI
  • Jehn, Lutz-Bernhard; Berg, Victoria; Kibler, Artur; Boerner, Eda; Waelscher, Julia; Budeus, Bettina; Seifert, Marc; Taube, Christian; Bonella, Francesco
    Flow cytometric evaluation of whole lung lavage (WLL) fluid from patients with pulmonary alveolar proteinosis (PAP) : preliminary findings
    International Congress of the European Respiratory Society (ERS) 2023 ; 9 - 13 September 2023, Milan, Italy,
    In: European Respiratory Journal (ERJ) , Jg. 62 2023, Nr. Supplement 67: ERS International Congress 2023 abstracts, PA3946
    DOI