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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Virologie
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in VitroIn: Viruses, Jg. 12, 2020, Nr. 2, 251DOI (Open Access)
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Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype-D infectionIn: Emerging Microbes & Infections, Jg. 9, 2020, Nr. 1, S. 928 – 939DOI (Open Access)
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Antiretroviral therapy suppresses rectal HIV-RNA shedding despite inflammation in MSM with rectal C. trachomatis and N. gonorrhoeae infections - A cross-sectional, single-center studyIn: Sexually Transmitted Infections, Jg. 95, 2019, Nr. 2, S. 95 – 98DOI (Open Access)
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Clinical Outcome and Viral Genome Variability of Hepatitis B Virus–Induced Acute Liver FailureIn: Hepatology, Jg. 69, 2019, Nr. 3, S. 993 – 1003
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Clinical and Virological Aspects of HBV Reactivation : A Focus on Acute Liver FailureIn: Viruses, Jg. 11, 2019, Nr. 9DOI (Open Access)
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Key mutations in HBsAg C-terminus correlate with lower HBsAg levels in vivo, hinder HBsAg release in vitro and affect HBsAg structural stability in HBeAg-negative chronic HBV genotype D infectionIn: Digestive and Liver Disease, Jg. 51, 2019, S. e60
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Rapid rebound of a preexisting CXCR4-tropic human immunodeficiency virus variant after allogeneic transplantation with CCR5 Δ32 homozygous stem cellsIn: Clinical Infectious Diseases (CID), Jg. 68, 2019, Nr. 4, S. 684 – 687DOI (Open Access)
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The detection of BKPyV genotypes II and IV after renal transplantation as a simple tool for risk assessment for PyVAN and transplant outcome already at early stages of BKPyV reactivationIn: Journal of Clinical Virology, Jg. 113, 2019, S. 14 – 19
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Clinical patterns associated with the concurrent detection of anti-HBs and HBV DNAIn: Journal of Medical Virology, Jg. 90, 2018, Nr. 2, S. 282 – 290
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Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in EuropeIn: BMC Infectious Diseases, Jg. 18, 2018, S. 251DOI (Open Access)
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Impact of immune suppressive agents on the BK-Polyomavirus non coding control regionIn: Antiviral Research, Jg. 159, 2018, S. 68 – 76
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Impact of low-level BK polyomavirus viremia on intermediate-term renal allograft functionIn: Transplant Infectious Disease, Jg. 20, 2018, Nr. 1, S. e12817
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Clinical course and core variability in HBV infected patients without detectable anti-HBc antibodiesIn: Journal of Clinical Virology, Jg. 93, 2017, S. 46 – 52
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HIV-1 persistent viremia is frequently followed by episodes of low-level viremiaIn: Medical Microbiology and Immunology, Jg. 206, 2017, Nr. 3, S. 203 – 215DOI, Online Volltext (Open Access)
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Impact of Immunosuppressive Drugs on the BK-Polyomavirus Non Coding Control Region (NCCR) ActivityIn: Transplant International, Jg. 30, 2017, Nr. Suppl. 4 SI, S. 29 Abstract P06
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In HBeAg-negative chronic HBV infection, HBsAg levels profoundly differ among HBV-genotypes and can be affected by the extent of HBsAg variability : Can quantitative HBsAg truly reflect intra-hepatic HBV reservoir?In: Digestive and Liver Disease, Jg. 49, 2017, Nr. 1, S. e45
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In HBeAg-negative chronic HBV infection, HBsAg levels profoundly vary among different HBV-genotypes and can be influenced by the degree of HBsAg variability : can quantitative HBsAg truly reflect intra-hepatic HBV reservoir?In: Journal of Hepatology, Jg. 66, 2017, Nr. 1 Suppl., S. S470
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Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitroIn: OncoTarget, Jg. 8, 2017, Nr. 9, S. 15704 – 15715DOI (Open Access)
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Pre-exposure prophylaxis failure with tenofovir disoproxilIn: AIDS, Jg. 31, 2017, Nr. 1, S. 176 – 177
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Role of Gag mutations in PI resistance in the Swiss HIV cohort study : bystanders or contributors?In: Journal of Antimicrobial Chemotherapy, Jg. 72, 2017, Nr. 3, S. 866 – 875DOI (Open Access)
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BK-Polyomavirus-Reaktivierung nach NierentransplantationIn: Der Nephrologe, Jg. 11, 2016, Nr. 6, S. 402 – 407
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Clinical patterns associated with the concurrent detection of anti-HBs and HBV DNAIn: Hepatology, Jg. 63, 2016, Nr. Suppl. 1, S. 900A
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Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy–Experienced Patients in Europe (CAPRE)In: The Journal of Infectious Diseases (JID), Jg. 213, 2016, Nr. 1, S. 39 – 48DOI (Open Access)
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Detection of hepatitis b virus DNA in the blood of a stem cell donor after granulocyte colony-stimulating factor treatmentIn: Hepatology, Jg. 64, 2016, Nr. 5, S. 1803 – 1805
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Interferon alpha subtype-specific suppression of HIV-1 infection in vivoIn: Journal of Virology, Jg. 90, 2016, Nr. 13, S. 6001 – 6013DOI (Open Access)
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Liver Failure due to Acute Viral Hepatitis (A-E)In: Visceral Medicine, Jg. 32, 2016, Nr. 2, S. 80 – 85
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No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohortsIn: Virology, Jg. 488, 2016, S. 88 – 95DOI (Open Access)
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Reduced Frequencies and Activation of Regulatory T Cells After the Treatment of HIV-1-Infected Individuals with the CCR5 Antagonist Maraviroc Are Associated with a Reduction in Viral Loads Rather Than a Direct Effect of the Drug on Regulatory T CellsIn: Viral Immunology, Jg. 29, 2016, Nr. 3, S. 192 – 196
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Treatment of fulminant acute Hepatitis B with nucles(t)id analogues is safe and does not lead to secondary chronification of Hepatitis BIn: Zeitschrift für Gastroenterologie, Jg. 54, 2016, Nr. 12, S. 1306 – 1311
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A hyper-glycosylation of HBV surface major hydrophilic region characterizes HBV reactivation driven by immunosuppression and affects HBsAg recognition in vitroIn: Journal of Hepatology, Jg. 62, 2015, Nr. Suppl. 2, S. S553
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A hyper-glycosylation of HBV surface major hydrophilic region correlates with immunosuppression-driven HBV reactivation and hampers HBsAg recognition in vitroIn: Digestive and Liver Disease, Jg. 47, 2015, Nr. Suppl. 1, S. e11 – e12
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A new ensemble coevolution system for detecting HIV-1 protein coevolutionIn: Biology Direct, Jg. 10, 2015, S. 1DOI (Open Access)
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Challenges in the diagnosis and prevention of viral infectionsIn: Laboratoriumsmedizin, Jg. 38, 2015, Nr. 2, S. 16 – 23
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Decades after recovery from hepatitis B and HBsAg clearance the CD8+ T cell response against HBV core is nearly undetectableIn: Journal of Hepatology, Jg. 63, 2015, Nr. 1, S. 13 – 19
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Early identification of renal transplant recipients with high risk of polyomavirus-associated nephropathyIn: Medical Microbiology and Immunology, Jg. 204, 2015, Nr. 6, S. 657 – 664
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Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppressionIn: Hepatology, Jg. 61, 2015, Nr. 3, S. 823 – 833DOI (Open Access)
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Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in EuropeIn: Clinical Gastroenterology and Hepatology, Jg. 13, 2015, Nr. 10, S. 1836 – 1842.e2
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ID: 41: Treatment with interferon alpha subtype 14 potently suppresses HIV infection in humanized miceIn: Cytokine, Jg. 76, 2015, Nr. 1, S. 71 – 72
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Increased frequency of JC-polyomavirus detection in rheumatoid arthritis patients treated with multiple biologicsIn: Medical Microbiology and Immunology, Jg. 204, 2015, Nr. 5, S. 613 – 618
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Indeterminate acute liver failure : it may be Hepatitis EIn: Journal of Viral Hepatitis, Jg. 22, 2015, Nr. Suppl. 2, S. 12
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Primarily oseltamivir-resistant influenza A (H1N1pdm09) virus evolving into a multidrug-resistant virus carrying H275Y and I223R neuraminidase substitutionsIn: Antiviral Therapy, Jg. 20, 2015, Nr. 1, S. 97 – 100
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Research letter : Novel tetra-peptide insertion in Gag-p6 ALIXbinding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patientsIn: AIDS, Jg. 28, 2015, Nr. 15, S. 2319 – 2322
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Specific mutations in the C-terminus domain of HBV surface antigen significantly correlate with low level of serum HBV-DNA in patients with chronic HBV infectionIn: Journal of Infection, Jg. 70, 2015, Nr. 3, S. 288 – 298
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Clinical performance of the novel DiaSorin LIAISON® XL murex : HBsAg Quant, HCV-Ab, HIV-Ab/Ag assaysIn: Journal of Clinical Virology, Jg. 59, 2014, Nr. 1, S. 44 – 49
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Determination of drug resistance and virus typology in HIV-1-positive pediatric patients in Istanbul, TurkeyIn: Intervirology, Jg. 57, 2014, Nr. 5, S. 297 – 299
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Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'In: Virologica Sinica, Jg. 29, 2014, Nr. 1, S. 40 – 47
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HIV-1 Gag C-terminal amino acid substitutions emerging under selective pressure of protease inhibitors in patient populations infected with different HIV-1 subtypesIn: Retrovirology, Jg. 11, 2014, Nr. 1, 79DOI (Open Access)
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Herausforderungen in der Diagnostik und Prävention von ViruserkrankungenIn: Laboratoriumsmedizin, Jg. 38, 2014, Nr. 2, S. 87 – 100
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More on Shift of HIV Tropism in Stem-Cell Transplantation with CCR5 Delta32/Delta32 MutationIn: The New England Journal of Medicine, Jg. 371, 2014, Nr. 25, S. 2438
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Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patientsIn: AIDS, Jg. 28, 2014, Nr. 15, S. 2319 – 2322DOI, Online Volltext (Open Access)
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Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutationIn: The New England Journal of Medicine, Jg. 371, 2014, Nr. 9, S. 880 – 882
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Spontaneous reactivation of hepatitis B virus replication in an HIV coinfected patient with isolated anti-Hepatitis B core antibodiesIn: Virology Journal, Jg. 11, 2014, 9DOI (Open Access)
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Time on drug analysis based on real life dataIn: Journal of the International AIDS Society, Jg. 17, 2014, Nr. 4 Suppl 3, S. 19790DOI (Open Access)
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Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigenIn: Journal of Infection, Jg. 67, 2013, Nr. 4, S. 303 – 312
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Functional conservation of HIV-1 Gag : implications for rational drug designIn: Retrovirology, Jg. 10, 2013, 126DOI (Open Access)
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High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolatesIn: Journal of Medical Virology, Jg. 85, 2013, Nr. 5, S. 775 – 779
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Inferring short-range linkage information from sequencing chromatogramsIn: PLoS ONE, Jg. 8, 2013, Nr. 12, S. e81687DOI (Open Access)
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Key genetic signatures in the whole pre-S1/Pre-S2/s gene correlate eith HBV-induced carcinogenesis by affecting HBsAG secretion and releaseIn: Journal of Hepatology, Jg. 58, 2013, Nr. Suppl. 1, S. S176
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Overlapping structure of hepatitis B virus (HBV) genome and immune selection pressure are critical forces modulating HBV evolutionIn: Journal of General Virology, Jg. 94, 2013, Nr. Pt 1, S. 143 – 149
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Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiersIn: BioData Mining, Jg. 4, 2011, Nr. 1, S. 26DOI, Online Volltext (Open Access)
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Predicting Bevirimat resistance of HIV-1 from genotypeIn: BMC Bioinformatics, Jg. 11, 2010, S. 37DOI (Open Access)
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Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patientsIn: Journal of Infection, Jg. 58, 2009, Nr. 1, S. 61 – 67
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Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.In: Antiviral Therapy, Jg. 11, 2006, Nr. 7, S. 879 – 887
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A hyper-glycosylation of HBV surface antigen characterizes immunosuppression-driven HBV reactivation and hinders HBsAg recognition in vitroIn: Journal of Hepatology. Amsterdam; Copenhagen; Oxford: Elsevier, Jg. 68, 2018, Nr. Suppl. 1, S. 765 – S766
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Key mutational patterns in HBsAg C-terminus profoundly affect HBsAg levels in HBeAg-negative chronic HBV genotype D infectionIn: Journal of Hepatology. Amsterdam; Copenhagen; Oxford: Elsevier, Jg. 68, 2018, Nr. Suppl. 1, S. 492 – S493
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Rapid rebound of a highly replication competent preexisting CXCR4-tropic HIV variant after allogeneic stem cell transplantation with CCR5D32 stem cellsIn: Journal of the International AIDS Society. Hoboken: Wiley, Jg. 21, 2018, Nr. Suppl. 6, S. 4DOI (Open Access)
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The presence of rare BKPYV genotypes after renal transplantation is associated with worse transplant outcome
27th Annual Meeting of the German Transplantation Society, Berlin, Germany, 7–10 November 2018,In: Transplant International. Lausanne: Frontiers Media, Jg. 31, 2018, Nr. Suppl. 5, S. 23DOI (Open Access) -
Detection of BK virus in patients after kidney transplantationIn: Transplant International. Lausanne: Frontiers Media, Jg. 29, 2016, Nr. Suppl. 3, S. 9 V030
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Immune-escape mutations and stop-codons in HBsAg circulates in a relevant proportion of patients with chronic HBV infection exposed to Anti-HBV drugs in Europe : Implications for HBV transmission in the setting of vaccination and disease progressionIn: Journal of Hepatology. Amsterdam; Copenhagen; Oxford: Elsevier, Jg. 64, 2016, Nr. 2, Suppl., S. S367 – S368
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Proktitiden mit N. gonorrhoeae/C. trachomatis führen zur Rekrutierung von HIV-Zielzellen aber nicht zu einer gesteigerten HIV-Sekretion
Leopoldina-Symposium und STI-Kongress, 18. und 19.–21. Juni 2014, Berlin,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 12, 2014, Nr. 10, S. 952 – 953 -
Shift of HIV-Tropism in a HIV-patient with large cell anaplastic T-cell-lymphoma undergoing allogeneic stem cell transplantation from a donor with homozygosity for the CCR5 delta32 mutation
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,In: Oncology Research and Treatment. Basel: Karger, Jg. 37, 2014, Nr. Suppl. 5, S. 38