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Prof. Dr. rer. nat. Mirko Trilling

Funktionen

  • Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Tang, Haihuan; Hu, Jie; Schmitz, Mona S.; Barbet, Kimberly; Xu, Dan; Wei, Zhen; Guo, Beinu; Mennerich, Denise; Yao, Chun; Liu, Jinxin; Li, Zhenghan; Wan, Yushun; Zhang, Xiaoyong; Wang, Kai; Tang, Ni; Yu, Zebo; Trilling, Mirko; Lin, Yong
    Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin
    In: Virus Research Jg. 350 (2024) 199485
    Online Volltext: dx.doi.org/ (Open Access)
  • Rohn, Hana; Elischer, Fynn; Larbig, Louisa; Jansen, Sarah; Schramm, Sabine; Otte, Mona; Konik, Margarethe; Paniskaki, Krystallenia; Weber, Peter; Reinold, Johanna; Gäckler, Anja; Krawczyk, Adalbert; Wilde, Benjamin; Trilling, Mirko; Michita, Rafael T.; Möhlendick, Birte; Siffert, Winfried; Brenner, Thorsten; Dinse, Hannah; Skoda, Eva M.; Horn, Peter; Witzke, Oliver; Rebmann, Vera
    Influence of HLA-G 3′ Untranslated Region Haplotypes and SNP +3422 Gene Variants as Host Genetic Factors on the Outcomes of SARS-CoV-2 Infection During Acute and Post-Acute Phases in a German Cohort
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 104 (2024) Nr. 6, e15799
    Online Volltext: dx.doi.org/ (Open Access)
  • Gerke, Carolin; Bauersfeld, Liane; Schirmeister, Ivo; Mireisz, Chiara Noemi-Marie; Oberhardt, Valerie; Mery, Lea; Wu, Di; Jürges, Christopher Sebastian; Spaapen, Robbert M.; Mussolino, Claudio; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Dölken, Lars; Paster, Wolfgang; Erhard, Florian; Hofmann, Maike; Schlosser, Andreas; Hengel, Hartmut; Momburg, Frank; Halenius, Anne
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
    In: eLife Jg. 13 (2024) e85560
    Online Volltext: dx.doi.org/ (Open Access)
  • Thomas, Alexander; Battenfeld, Thomas; Kraiselburd, Ivana; Anastasiou, Olympia; Dittmer, Ulf; Dörr, Ann-Kathrin; Dörr, Adrian; Elsner, Carina; Gosch, Jule; Le-Trilling, Vu Thuy Khanh; Magin, Simon; Scholtysik, René; Yilmaz, Pelin; Trilling, Mirko; Schöler, Lara; Köster, Johannes; Meyer, Folker
    UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an example
    In: BMC Genomics Jg. 25 (2024) Nr. 1, 647
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Anastasiou, Olympia E.; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    A simple algorithm based on initial Ct values predicts the duration to SARS-CoV-2 negativity and allows more efficient test-to-release and return-to-work schedules
    In: Diagnostic Microbiology and Infectious Disease Jg. 106 (2023) Nr. 3, 115949
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Ebel, Jana‐Fabienne; Baier, Franziska; Wohlgemuth, Kerstin; Pfeifer, Kai Robin; Mookhoek, Aart; Krebs, Philippe; Determann, Madita; Katschinski, Benjamin; Adamczyk, Alexandra; Lange, Erik; Klopfleisch, Robert; Lange, Christian; Sokolova, Viktoriya; Trilling, Mirko; Westendorf, Astrid
    Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cells
    In: European Journal of Immunology Jg. 53 (2023) Nr. 2, 2249940
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Holtkamp, Caroline; Schöler, Lara; Anastasiou, Olympia E.; Brune, Bastian; Fessmann, Kai; Elsner, Carina; Möhlendick, Birte; Ciuciulkaite, Ieva; Dudda, Marcel; Trilling, Mirko; Dittmer, Ulf; Spors, Jörg; Le-Trilling, Vu Thuy Khanh
    Antibody responses elicited by mRNA vaccination in firefighters persist six months and correlate inversely with age and directly with BMI
    In: Heliyon Jg. 9 (2023) Nr. 1, e12746
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Alt, Mira; Wolf, Susanne; van de Sand, Lukas; Dittrich, Robin; Tertel, Tobias; Brochhagen, Leonie; Dirks, Miriam; Aufderhorst, Ulrich Wilhelm; Thümmler, Laura; Otte, Mona; Rainer, Kordula; Dittmer, Ulf; Giebel, Bernd; Trilling, Mirko; Heilingloh, Christiane Silke; Lotfi, Ramin; Roggendorf, Michael; Witzke, Oliver; Krawczyk, Adalbert
    Cell-to-cell spread inhibiting antibodies constitute a correlate of protection against herpes simplex virus type 1 reactivations : A retrospective study
    In: Frontiers in Immunology Jg. 14 (2023) 1143870
    Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Maaßen, Fabienne; Katschinski, Benjamin; Hengel, Hartmut; Trilling, Mirko
    Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation
    In: Frontiers in Immunology Jg. 14 (2023) 1170300
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Stupia, Simone; Heeke, Christina; Brüggemann, Alicia; Zaremba-Montenari, Anne; Thier, Beatrice; Kretz, Julia; Sucker, Antje; Philip, Manuel; Zelinskyy, Gennadiy; Ferrone, Soldano; Rösch, Alexander; Horn, Susanne; Hadaschik, Eva; Schadendorf, Dirk; Trilling, Mirko; Dittmer, Ulf; Griewank, Klaus; Zhao, Fang; Paschen, Annette
    HLA class II loss and JAK1/2 deficiency coevolve in melanoma leading to CD4 T cell and IFNγ cross-resistance
    In: Clinical Cancer Research Jg. 29 (2023) Nr. 15, S. 2894 - 2907
    Online Volltext: dx.doi.org/
  • Unterberg, M.; Ehrentraut, S.F.; Bracht, T.; Wolf, A.; Haberl, Helge; von Busch, A.; Rump, K.; Ziehe, D.; Bazzi, M.; Thon, P.; Sitek, B.; Marcus, K.; Bayer, M.; Schork, K.; Eisenacher, M.; Ellger, B.; Oswald, D.; Wappler, F.; Defosse, J.; Henzler, D.; Köhler, T.; Zarbock, A.; Putensen, C.P.; Schewe, J.C.; Frey, U.H.; Anft, M.; Babel, N.; Steinmann, E.; Brüggemann, Y.; Trilling, Mirko; Schlüter, A.; Nowak, H.; Adamzik, Michael; Rahmel, T.; Koos, B.
    Human cytomegalovirus seropositivity is associated with reduced patient survival during sepsis
    In: Critical Care: The Online Intensive Care Journal Jg. 27 (2023) Nr. 1, 417
    Online Volltext: dx.doi.org/ (Open Access)
  • Westmeier, Jaana; Brochtrup, Annika; Paniskaki, Krystallenia; Karakoese, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Limmer, Andreas; Mittermüller, Daniela; Liu, Jia; Zheng, Xin; Koval, Tetiana; Kaidashev, Igor; Berger, Marc Moritz; Herbstreit, Frank; Brenner, Thorsten; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients
    In: Frontiers in Immunology Jg. 14 (2023) 1236374
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Jagnjić, Andreja; Brizić, Ilija; Eilbrecht, Mareike; Wohlgemuth, Kerstin; Rožmanić, Carmen; Herdman, Alan; Hoffmann, Katja; Westendorf, Astrid M.; Hengel, Hartmut; Jonjić, Stipan; Trilling, Mirko
    Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus
    In: npj Vaccines Jg. 8 (2023) Nr. 1, 8
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Specka, Michael; Kröckert, Tobias; Trilling, Mirko; Bonnet, Udo; Schifano, Fabrizio; Scherbaum, Norbert
    Opiate maintenance patients’ attitudes and self-reported adherence to protective measures against SARS-CoV-2 infections
    In: Frontiers in Psychiatry Jg. 14 (2023) 1254053
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rohn, Hana; Schramm, Sabine; Pansikaki, Krystallenia; Jansen, Sarah; Hendriks, Celina; Platte, Maximilian; Konik, Margarethe; Dolff, Sebastian; Wilde, Benjamin; Kordelas, Lambros; Trilling, Mirko; Krawczyk, Adalbert; Horn, Peter; Witzke, Oliver; Rebmann, Vera
    Peripheral HLA-G/ILT-2 immune checkpoint axis in acute and convalescent COVID-19 patients
    In: Human Immunology Jg. 84 (2023) Nr. 8, S. 393 - 400
    Online Volltext: dx.doi.org/ (Open Access)
  • Di Vito, Clara; Coianiz, Nicolò; Calvi, Michela; Terzoli, Sara; Zaghi, Elisa; Puccio, Simone; Frigo, Alessandro; Mariotti, Jacopo; De Philippis, Chiara; Mannina, Daniele; Sarina, Barbara; Mineri, Rossana; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Castagna, Luca; Bramanti, Stefania; Santoro, Armando; Mavilio, Domenico
    Persistence of KIRⁿeg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivation
    In: Frontiers in Immunology Jg. 14 (2023) 1266051
    Online Volltext: dx.doi.org/ (Open Access)
  • Gonzalez-Rubio, Julian; Le-Trilling, Vu Thuy Khanh; Baumann, Lea; Cheremkhina, Maria; Kubiza, Hannah; Luengen, Anja E.; Reuter, Sebastian; Taube, Christian; Ruetten, Stephan; Duarte Campos, Daniela; Cornelissen, Christian G.; Trilling, Mirko; Thiebes, Anja Lena
    SARS-CoV-2 particles promote airway epithelial differentiation and ciliation
    In: Frontiers in Bioengineering and Biotechnology Jg. 11 (2023) 1268782
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Liu, Jing; Deng, Hui; Yang, Xuecheng; Wang, Hua; Feng, Xuemei; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Wang, Baoju; Yang, Dongliang; Zheng, Xin; Liu, Jia
    SARS-CoV-2-specific T cell responses wane profoundly in convalescent individuals 10 months after primary infection
    In: Virologica Sinica Jg. 38 (2023) Nr. 4, S. 606 - 619
    Online Volltext: dx.doi.org/ (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Banchenko, Sofia; Paydar, Darius; Leipe, Pia Madeleine; Binting, Lukas; Lauer, Simon; Graziadei, Andrea; Klingen, Robin; Gotthold, Christine; Bürger, Jörg; Bracht, Thilo; Sitek, Barbara; Lebbink, Robert Jan; Malyshkina, Anna; Mielke, Thorsten; Rappsilber, Juri; Spahn, Christian; Voigt, Sebastian; Trilling, Mirko; Schwefel, David
    Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
    In: The EMBO Journal Jg. 42 (2023) Nr. 5, e112351
    Online Volltext: dx.doi.org/ (Open Access)
  • Karakoese, Zehra; Le-Trilling, Vu Thuy Khanh; Schuhenn, Jonas; Francois, Sandra; Lu, Mengji; Liu, Jia; Trilling, Mirko; Hoffmann, Daniel; Dittmer, Ulf; Sutter, Kathrin
    Targeted mutations in IFNα2 improve its antiviral activity against various viruses
    In: mBio Jg. 14 (2023) Nr. 6, e02357-23
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Vollmer-Raschdorf, Stephanie; Rashidi-Alavijeh, Jassin; Voigt, Sebastian; Hengel, Hartmut; Borchardt, Benjamin; Huzly, Daniela; Hüßler, Eva-Maria; In der Schmitten, Jürgen; Halenius, Anne; Willuweit, Katharina; Botzenhardt, Suzan; Trilling, Mirko; Boettler, Tobias; Dehnen, Dorothea
    Tiza-Titre increase and enhanced immunity through an adjuvanted, recombinant herpes zoster subunit vaccine in patients with liver cirrhosis and post-liver transplantation : A study protocol for a prospective cohort study
    In: BMJ Open Jg. 13 (2023) Nr. 11, e074461
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Xiaoyan; Kerkmann, Leonie; Hetzel, Mario; Windmann, Sonja; Trilling, Mirko; Zhang, Wenli; Ehrhardt, Anja; Bayer, Wibke
    Analysis of the Prevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Student Cohorts Reveals Low-Prevalence Types and a Decline in Binding Antibody Levels during the SARS-CoV-2 Pandemic
    In: Journal of Virology Jg. 96 (2022) Nr. 22, e0113322
    Online Volltext: dx.doi.org/
  • Schuhenn, Jonas; Meister, Toni Luise; Todt, Daniel; Bracht, Thilo; Schork, Karin; Billaud, Jean-Noel; Elsner, Carina; Heinen, Natalie; Karakoese, Zehra; Haid, Sibylle; Kumar, Sriram; Brunotte, Linda; Eisenacher, Martin; Di, Yunyun; Lew, Jocelyne; Falzarano, Darryl; Chen, Jieliang; Yuan, Zhenghong; Pietschmann, Thomas; Wiegmann, Bettina; Uebner, Hendrik; Taube, Christian; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Krawczyk, Adalbert; Ludwig, Stephan; Sitek, Barbara; Steinmann, Eike; Dittmer, Ulf; Lavender, Kerry J.; Sutter, Kathrin; Pfaender, Stephanie
    Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 119 (2022) Nr. 8, e2111600119
    Online Volltext: dx.doi.org/ (Open Access)
  • Dehnen, Dorothea; Dehnen, Katja; Trilling, Mirko; Fiedler, Melanie; Drexler, Julia; Goralski, Marcel; Le-Trilling, Vu Thuy Khanh; Schöler, Lara; Jöckel, Karl-Heinz; Heßbrügge, Martina
    Discrepancy between frequent occurrence of COVID-19-like symptoms and low seroconversion rates among healthcare workers
    In: Journal of Medical Virology Jg. 94 (2022) Nr. 3: Special Issue on New coronavirus (2019‐nCoV or SARS‐CoV‐2) and the outbreak of the respiratory illness (COVID‐19): Part‐XVIII, S. 951 - 957
    Online Volltext: dx.doi.org/ (Open Access)
  • Rohn, Hana; Lang, Cordula; Schramm, Sabine; Heinemann, Falko M.; Trilling, Mirko; Gäckler, Anja; Witzke, Oliver; Horn, Peter; Rebmann, Vera
    Effect of HLA-G5 Immune Checkpoint Molecule on the Expression of ILT-2, CD27, and CD38 in Splenic B cells
    In: Journal of Immunology Research Jg. 2022 (2022) 4829227
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schöler, Lara; Le-Trilling, Vu Thuy Khanh; Dittmer, Ulf; Fiedler, Melanie; Trilling, Mirko
    Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies virus neutralizing antibodies
    In: PLoS Neglected Tropical Diseases Jg. 16 (2022) Nr. 5, e0010425
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Mennerich, Denise; Schuler, Corinna; Sakson, Roman; Lill, Julia K.; Kasarla, Siva Swapna; Kopczynski, Dominik; Loroch, Stefan; Flores-Martinez, Yulia; Katschinski, Benjamin; Wohlgemuth, Kerstin; Gunzer, Matthias; Meyer, Folker; Phapale, Prasad; Dittmer, Ulf; Sickmann, Albert; Trilling, Mirko
    Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro
    In: BMC Biology (incorporating Journal of Biology) Jg. 20 (2022) Nr. 1, 264
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Turki, Amin T.; Tsachakis-Muck, Nikolaos; Leserer, Saskia; Crivello, Pietro; Liebregts, Tobias; Betke, Luisa; Alashkar, Ferras; Leimkuhler, Nils B.; Trilling, Mirko; Fleischhauer, Katharina; Beelen, Dietrich
    Impact of CMV reactivation on relapse of acute myeloid leukemia after HCT is dependent on disease stage and ATG
    In: Blood Advances Jg. 6 (2022) Nr. 1, S. 28 - 36
    Online Volltext: dx.doi.org/ (Open Access)
  • Möhlendick, Birte; Čiučiulkaitė, Ieva; Elsner, Carina; Anastasiou, Olympia E.; Trilling, Mirko; Wagner, Bernd; Zwanziger, Denise; Jöckel, Karl-Heinz; Dittmer, Ulf; Siffert, Winfried
    Individuals With Weaker Antibody Responses After Booster Immunization Are Prone to Omicron Breakthrough Infections
    In: Frontiers in Immunology Jg. 13 (2022) 907343
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Wang, Kai; Mennerich, Denise; Hu, Jie; Zhao, Zhenyu; Zheng, Jiaxin; Deng, Yingying; Katschinski, Benjamin; Xu, Shilei; Zhang, Guiji; Cai, Xuefei; Hu, Yuan; Wang, Jianwei; Lu, Mengji; Huang, Ailong; Tang, Ni; Trilling, Mirko; Lin, Yong
    Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 483 - 497
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Krempe, Friederike; Schöler, Lara; Katschinski, Benjamin; Herrmann, Anke; Anastasiou, Olympia E.; Elsner, Carina; Roß, R. Stefan; Scholz, Friedrich; Dittmer, Ulf; Miethe, Peter; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    A rapid test recognizing mucosal SARS-CoV-2-specific antibodies distinguishes prodromal from convalescent COVID-19
    In: iScience Jg. 24 (2021) Nr. 10, 103194
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Jia; Yang, Xuecheng; Wang, Hua; Li, Ziwei; Deng, Hui; Liu, Jing; Xiong, Shue; He, Junyi; Feng, Xuemei; Guo, Chunxia; Wang, Weixian; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Senff, Tina; Menne, Christopher; Timm, Jörg; Zhang, Yanfang; Deng, Fei; Lu, Yinping; Wu, Jun; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Wang, Baoju; Zheng, Xin
    Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairment
    In: mBio Jg. 12 (2021) Nr. 2, S. e00085 - 21
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Deng, Hui; Wang, Hua; Feng, Xuemei; Quan, Xufeng; Wang, Xiaoyan; Li, Sumeng; Lu, Sihong; Yang, Xuecheng; Wang, Baoju; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Zheng, Xin; Liu, Jia
    Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World Setting
    In: Frontiers in Immunology Jg. 12 (2021) 802858
    Online Volltext: dx.doi.org/ (Open Access)
  • Leserer, Saskia; Bayraktar, Evren; Trilling, Mirko; Bogdanov, Rashit; Arrieta-Bolaños, Esteban; Tsachakis-Mück, Nikolaos; Crivello, Pietro; Koldehoff, Michael; Maaßen, Fabienne; Roß, Rudolf Stefan; Fleischhauer, Katharina; Beelen, Dietrich; Turki, Amin T.
    Cytomegalovirus kinetics after hematopoietic cell transplantation reveal peak titers with differential impact on mortality, relapse and immune reconstitution
    In: American Journal of Hematology Jg. 96 (2021) Nr. 4, S. 436 - 445
    Online Volltext: dx.doi.org/ (Open Access)
  • Xiang, Tiandan; Liang, Boyun; Fang, Yaohui; Lu, Sihong; Li, Sumeng; Wang, Hua; Li, Huadong; Yang, Xiaoli; Shen, Shu; Zhu, Bin; Wang, Baoju; Wu, Jun; Liu, Jia; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Trilling, Mirko; Deng, Fei; Zheng, Xin
    Declining Levels of Neutralizing Antibodies Against SARS-CoV-2 in Convalescent COVID-19 Patients One Year Post Symptom Onset
    In: Frontiers in Immunology Jg. 12 (2021) 708523
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Trilling, Mirko
    Erratum to: Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants
    In: Basic Research in Cardiology Jg. 116 (2021) Nr. 1, 43
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhou, Li; He, Rui; Fang, Peining; Li, Mengqi; Yu, Haisheng; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Lin, Yong; Zhang, Rui; Trilling, Mirko; Bröring, Ruth; Lu, Mengji; Zhu, Ying; Liu, Shi
    Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 98
    Online Volltext: dx.doi.org/ (Open Access)
  • Konik, Margarethe; Lindemann, Monika; Zettler, Markus; Meller, Lara; Dolff, Sebastian; Rebmann, Vera; Horn, Peter; Dittmer, Ulf; Krawczyk, Adalbert; Schipper, Leonie; Trilling, Mirko; Anastasiou, Olympia Evdoxia; Schwarzkopf, Sina; Thümmler, Laura; Taube, Christian; Schöbel, Christoph; Brenner, Thorsten; Skoda, Eva-Maria; Wilde, Benjamin; Gäckler, Anja; Witzke, Oliver; Rohn, Hana
    Long-term sars-cov-2 specific immunity is affected by the severity of initial covid-19 and patient age
    In: Journal of Clinical Medicine (JCM) Jg. 10 (2021) Nr. 19, 4606
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Flores-Martínez, Yulia Alejandra; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Nedd8-activating enzyme is a druggable host dependency factor of human and mouse cytomegalovirus
    In: Viruses Jg. 13 (2021) Nr. 8, 1610
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wu, Jun; Liang, Bo-Yun; Fang, Yao-Hui; Wang, Hua; Yang, Xiao-Li; Shen, Shu; Chen, Liang-Kai; Li, Su-Meng; Lu, Si-Hong; Xiang, Tian-Dan; Liu, Jia; Le-Trilling, Vu Thuy Khanh; Lu, Mengji; Yang, Dong-Liang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral Immunity
    In: Frontiers in Immunology Jg. 12 (2021) 722027
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Klingen, Robin L.; Katschinski, Benjamin; Anastasiou, Olympia E.; Roß, Rudolf Stefan; Dittmer, Ulf; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Over 90% of clinical swabs used for SARS-CoV-2 diagnostics contain sufficient nucleic acid concentrations
    In: Journal of Medical Virology Jg. 93 (2021) Nr. 5, S. 2848 - 2856
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, Hongming; Rückborn, Meike; Le-Trilling, Vu Thuy Khanh; Zhu, Dan; Yang, Shangqing; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Yinping; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Trilling, Mirko; Liu, Jia
    Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in mice
    In: European Journal of Immunology Jg. 51 (2021) Nr. 2, S. 393 - 407
    Online Volltext: dx.doi.org/ (Open Access)
  • Cherneha, Maxim; Korth, Johannes; Kaulfuß, Meike; Trilling, Mirko; Widera, Marek; Rohn, Hana; Dolff, Sebastian; Babel, Nina; Hörning, Andre; Kribben, Andreas; Witzke, Oliver
    Reactivations of Latent Viral Infections Are Associated with an Increased Thr389 p70S6k Phosphorylation in Peripheral Lymphocytes of Renal Transplant Recipients
    In: Viruses Jg. 13 (2021) Nr. 3, 424
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wu, Jun; Liang, Boyun; Chen, Cunrong; Wang, Hua; Fang, Yaohui; Shen, Shu; Yang, Xiaoli; Wang, Baoju; Chen, Liangkai; Chen, Qi; Wu, Yang; Liu, Jia; Yang, Xuecheng; Li, Wei; Zhu, Bin; Zhou, Wenqing; Wang, Huan; Li, Sumeng; Lu, Sihong; Liu, Di; Li, Huadong; Krawczyk, Adalbert; Lu, Mengji; Yang, Dongliang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 1813
    Online Volltext: dx.doi.org/ (Open Access)
  • Korth, Johannes; Wilde, Benjamin; Dolff, Sebastian; Frisch, Jasmin; Jahn, Michael; Krawczyk, Adalbert; Trilling, Mirko; Schipper, Leonie; Cordes, Sebastian; Ross, Birgit; Lindemann, Monika; Kribben, Andreas; Dittmer, Ulf; Witzke, Oliver; Herrmann, Anke; Anastasiou, Olympia Evdoxia
    Sars-cov-2 seroprevalence in healthcare workers in Germany : A follow-up study
    In: International Journal of Environmental Research and Public Health = IJERPH Jg. 18 (2021) Nr. 9, 4540
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zou, Shi; Du, Yanqin; Huang, Shunmei; Chen, Mingfa; Yang, Xiaoli; Li, Sumeng; Chen, Yingshan; Han, Meihong; Li, Jia; Yu, Qing; Littwitz-Salomon, Elisabeth; Huang, Hongming; Trilling, Mirko; Liu, Shi; Pei, Rongjuan; Liu, Jia; Wang, Baoju; Zheng, Xin; Lu, Mengji; Dittmer, Ulf; Sun, Shuilin; Yang, Dongliang; Wu, Jun
    Simultaneous or Prior Activation of Intrahepatic Type I Interferon Signaling Leads to Hepatitis B Virus Persistence in a Mouse Model
    In: Journal of Virology Jg. 95 (2021) Nr. 24, e00034-21
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zaghi, Elisa; Calvi, Michela; Puccio, Simone; Spata, Gianmarco; Terzoli, Sara; Peano, Clelia; Roberto, Alessandra; De Paoli, Federica; van Beek, Jasper J.P.; Mariotti, Jacopo; De Philippis, Chiara; Sarina, Barbara; Mineri, Rossana; Bramanti, Stefania; Santoro, Armando; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Marcenaro, Emanuela; Castagna, Luca; Di Vito, Clara; Lugli, Enrico; Mavilio, Domenico
    Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT
    In: JCI Insight Jg. 6 (2021) Nr. 12, e146973
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhao, Zhenyu; Lu, Kefeng; Mao, Binli; Liu, Shi; Trilling, Mirko; Huang, Ailong; Lu, Mengji; Lin, Yong
    The interplay between emerging human coronavirus infections and autophagy
    In: Emerging Microbes & Infections Jg. 10 (2021) Nr. 1, S. 196 - 205
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bormann, Maren; Alt, Mira; Schipper, Leonie; van de Sand, Lukas; Le-Trilling, Vu Thuy Khanh; Rink, Lydia; Heinen, Natalie; Madel, Rabea Julia; Otte, Mona; Wuensch, Korbinian; Heilingloh, Christiane Silke; Mueller, Thorsten; Dittmer, Ulf; Elsner, Carina; Pfaender, Stephanie; Trilling, Mirko; Witzke, Oliver; Krawczyk, Adalbert
    Turmeric root and its bioactive ingredient curcumin effectively neutralize sars-cov-2 in vitro
    In: Viruses Jg. 13 (2021) Nr. 10, 1914
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Shichuan; Trilling, Mirko; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Zheng, Xin; Yang, Dongliang; Liu, Jia
    A Crowned Killer’s Résumé : Genome, Structure, Receptors, and Origin of SARS-CoV-2
    In: Virologica Sinica (2020)
    Online Volltext: dx.doi.org/ (Open Access)
  • Schöler, Lara; Le-Trilling, Vu Thuy Khanh; Eilbrecht, Mareike; Mennerich, Denise; Anastasiou, Olympia E.; Krawczyk, Adalbert; Herrmann, Anke; Dittmer, Ulf; Trilling, Mirko
    A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds
    In: Frontiers in Immunology Jg. 11 (2020) S. 573526
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A.; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D.; Tenbusch, Matthias; Dietze, Kirsten; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S.; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid; Dittmer, Ulf; Zelinskyy, Gennadiy
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
    In: PLoS Pathogens Jg. 16 (2020) Nr. 3, e1008340
    Online Volltext: dx.doi.org/ (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Erratum for Westmeier et al., "Impaired Cytotoxic CD8⁺ T Cell Response in Elderly COVID-19 Patients"
    In: mBio Jg. 11 (2020) Nr. 5, S. 02243 - 02220
    Online Volltext: dx.doi.org/ (Open Access)
  • Rohn, Hana; Schwich, Esther; Tomoya Michita, Rafael; Schramm, Sabine; Dolff, Sebastian; Gäckler, Anja; Korth, Johannes; Heinemann, Falko M.; Wilde, Benjamin; Trilling, Mirko; Horn, Peter; Kribben, Andreas; Witzke, Oliver; Rebmann, Vera
    HLA-G 3′ untranslated region gene variants are promising prognostic factors for BK polyomavirus replication and acute rejection after living-donor kidney transplant
    In: Human Immunology Jg. 81 (2020) Nr. 4, S. 141 - 146
    Online Volltext: dx.doi.org/
  • Heilingloh, Christiane Silke; Lull, Christopher; Kleiser, Elissa; Alt, Mira; Schipper, Leonie; Witzke, Oliver; Trilling, Mirko; Eis-Hübinger, Anna-Maria; Dittmer, Ulf; Krawczyk, Adalbert
    Herpes Simplex Virus Type 2 Is More Difficult to Neutralize by Antibodies Than Herpes Simplex Virus Type 1
    In: Vaccines Jg. 8 (2020) Nr. 3, S. 478
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Trilling, Mirko
    Im Rennen der Roten Königin : Evolutionäres Wettrüsten zwischen Herpesviren und ihren Wirten
    In: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 62 - 69
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Impaired cytotoxic CD8⁺ T cell response in elderly COVID-19 patients
    In: mBio Jg. 11 (2020) Nr. 5, S. e02243 - 20
    Online Volltext: dx.doi.org/ (Open Access)
  • Yu, Haisheng; Li, Menqui; He, Rui; Fang, Peining; Wang, Qiming; Yi, Yu; Wang, Fubing; Zhou, Li; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Liu, Dan; Trilling, Mirko; Bröring, Ruth; Wiemer, Erik A.C.; Lu, Mengji; Zhu, Ying; Liu, Shi
    Major Vault Protein Promotes Hepatocellular Carcinoma Through Targeting Interferon Regulatory Factor 2 and Decreasing p53 Activity
    In: Hepatology Jg. 72 (2020) Nr. 2, S. 518 - 534
    Online Volltext: dx.doi.org/
  • Eilbrecht, Mareike; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication
    In: Frontiers in Cellular and Infection Microbiology Jg. 10 (2020) 171
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, Jia; Zheng, Xin; Tong, Qiaoxia; Li, Wei; Wang, Baoju; Sutter, Kathrin; Trilling, Mirko; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang
    Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV
    In: Journal of Medical Virology Jg. 92 (2020) Nr. 5, S. 491 - 494
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Heilingloh, Christiane Silke; Aufderhorst, Ulrich Wilhelm; Schipper, Leonie; Dittmer, Ulf; Witzke, Oliver; Yang, Dongliang; Zheng, Xin; Sutter, Kathrin; Trilling, Mirko; Alt, Mira; Steinmann, Eike; Krawczyk, Adalbert
    Susceptibility of SARS-CoV-2 to UV irradiation
    In: American Journal of Infection Control Jg. 48 (2020) Nr. 10, S. 1273 - 1275
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Such, Lina; Zhao, Fang; Liu, Derek; Thier, Beatrice; Le-Trilling, Vu Thuy Khanh; Sucker, Antje; Coch, Christoph; Pieper, Natalia; Howe, Sebastian; Bhat, Hilal; Kalkavan, Halime; Ritter, Cathrin; Brinkhaus, Robin; Ugurel, Selma; Köster, Johannes; Seifert, Ulrike; Dittmer, Ulf; Schuler, Martin; Lang, Karl S.; Kufer, Thomas A.; Hartmann, Gunther; Becker, Jürgen; Horn, Susanne; Ferrone, Soldano; Liu, David; Van Allen, Eliezer M.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Paschen, Annette
    Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy
    In: The Journal of Clinical Investigation (JCI) Jg. 130 (2020) Nr. 8, S. 4266 - 4281
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Becker, Tanja; Nachshon, Aharon; Stern-Ginossar, Noam; Schöler, Lara; Voigt, Sebastian; Hengel, Hartmut; Trilling, Mirko
    The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity
    In: Cell Reports Jg. 30 (2020) Nr. 7, S. 2248 - 2260.e5
    Online Volltext: dx.doi.org/ (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Ub to no good : How cytomegaloviruses exploit the ubiquitin proteasome system
    In: Virus Research Jg. 281 (2020) S. 197938
    Online Volltext: dx.doi.org/
  • Becker, Tanja; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Cellular Cullin RING Ubiquitin Ligases : Druggable Host Dependency Factors of Cytomegaloviruses
    In: International Journal of Molecular Sciences (IJMS) Jg. 20 (2019) Nr. 7, S. 1636
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rohn, Hana; Michita, Rafael Tomoya; Schramm, Sabine; Dolff, Sebastian; Gäckler, Anja; Korth, Johannes; Heinemann, Falko M.; Wilde, Benjamin; Trilling, Mirko; Horn, Peter; Kribben, Andreas; Witzke, Oliver; Rebmann, Vera
    HLA-E Polymorphism Determines Susceptibility to BK Virus Nephropathy after Living-Donor Kidney Transplant
    In: Cells Jg. 8 (2019) Nr. 8, S. 847
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bongard, Nadine; Le-Trilling, Vu Thuy Khanh; Malyshkina, Anna; Rückborn, Meike; Wohlgemuth, Kerstin; Wensing, Ina; Windmann, Sonja; Dittmer, Ulf; Trilling, Mirko; Bayer, Wibke
    Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection
    In: PLoS Pathogens Jg. 15 (2019) Nr. 9, e1008043
    Online Volltext: dx.doi.org/ (Open Access)
  • Winkler, Roni; Gillis, Ella; Lasman, Lior; Safra, Modi; Geula, Shay; Soyris, Clara; Nachshon, Aharon; Tai-Schmiedel, Julie; Friedman, Nehemya; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Mandelboim, Michal; Hanna, Jacob H.; Schwartz, Schraga; Stern-Ginossar, Noam
    Publisher Correction : m6A modification controls the innate immune response to infection by targeting type I interferons
    In: Nature Immunology Jg. 20 (2019) Nr. 2, S. 243
    Online Volltext: dx.doi.org/ (Open Access)
  • Winkler, Roni; Gillis, Ella; Lasman, Lior; Safra, Modi; Geula, Shay; Soyris, Clara; Nachshon, Aharon; Tai-Schmiedel, Julie; Friedman, Nehemya; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Mandelboim, Michal; Hanna, Jacob H.; Schwartz, Schraga; Stern-Ginossar, Noam
    m⁶A modification controls the innate immune response to infection by targeting type I interferons
    In: Nature Immunology Jg. 20 (2019) S. 173 - 183
    Online Volltext: dx.doi.org/
  • Landsberg, Christine D.; Megger, Dominik A.; Hotter, Dominik; Rückborn, Meike U.; Eilbrecht, Mareike; Rashidi-Alavijeh, Jassin; Howe, Sebastian; Heinrichs, Stefan; Sauter, Daniel; Sitek, Barbara; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx
    In: Frontiers in Immunology Jg. 9 (2018) S. 2978
    Online Volltext: dx.doi.org/ (Open Access)
  • Khosa, Sakshi; Scholz, Romy; Schwarz, Christian; Trilling, Mirko; Hengel, Hartmut; Jaeger, Karl-Erich; Smits, Sander H.J.; Schmitt, Lutz
    An A/U-rich enhancer region is required for high-level protein secretion through the HlyA type I secretion system
    In: Applied and Environmental Microbiology Jg. 84 (2018) Nr. 1, S. e01163 - 17
    Online Volltext: dx.doi.org/ (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Wohlgemuth, Kerstin; Rückborn, Meike U.; Jagnjic, Andreja; Maaßen, Fabienne; Timmer, Lejla; Katschinski, Benjamin; Trilling, Mirko
    STAT2-Dependent immune responses ensure host survival despite the presence of a potent viral antagonist
    In: Journal of Virology Jg. 92 (2018) Nr. 14, S. e00296 - 18.
    Online Volltext: dx.doi.org/ (Open Access)
  • Guberina, Hana; Da Silva Nardi, Fabiola; Michita, Rafael Tomoya; Dolff, Sebastian; Bienholz, Anja; Heinemann, Falko M.; Wilde, Benjamin; Trilling, Mirko; Horn, Peter; Kribben, Andreas; Witzke, Oliver; Rebmann, Vera
    Susceptibility of HLA-E*01:03 Allele Carriers to Develop Cytomegalovirus Replication After Living-Donor Kidney Transplantation
    In: The Journal of Infectious Diseases (JID) Jg. 217 (2018) Nr. 12, S. 1918 - 1922
    Online Volltext: dx.doi.org/ (Open Access)
  • Rohn, Hana; Tomoya Michita, Rafael; Schwich, Esther; Dolff, Sebastian; Gäckler, Anja; Horn, Peter; Kribben, Andreas; Trilling, Mirko; Le-Trilling, Vu Thuy Khanh; Wilde, Benjamin; Korth, Johannes; Heinemann, Falko M.; Witzke, Oliver; Rebmann, Vera
    The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients
    In: Frontiers in Immunology Jg. 9 (2018) S. 917
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Shinde, Prashant V.; Xu, Haifeng C.; Maney, Sathish Kumar; Kloetgen, Andreas; Namineni, Sukumar; Zhuang, Yuan; Honke, Nadine; Shaabani, Namir; Bellora, Nicolas; Doerrenberg, Mareike; Trilling, Mirko; Pozdeev, Vitaly I.; van Rooijen, Nico; Scheu, Stefanie; Pfeffer, Klaus; Crocker, Paul R.; Tanaka, Masato; Duggimpudi, Sujitha; Knolle, Percy; Heikenwalder, Mathias; Ruland, Jürgen; Mak, Tak W.; Brenner, Dirk; Pandyra, Aleksandra A.; Hoell, Jessica I.; Borkhardt, Arndt; Häussinger, Dieter; Lang, Karl S.; Lang, Philipp A.
    Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection
    In: Journal of Virology Jg. 92 (2018) Nr. 3, S. e01637 - 17
    Online Volltext: dx.doi.org/ (Open Access)
  • Sucker, Antje; Zhao, Fang; Pieper, Natalia; Heeke, Christina; Maltaner, Raffaela; Stadtler, Nadine; Real, Birgit; Bielefeld, Nicola; Howe, Sebastian; Weide, Benjamin; Gutzmer, Ralf; Utikal, Jochen; Loquai, Carmen; Gogas, Helen; Klein-Hitpaß, Ludger; Zeschnigk, Michael; Westendorf, Astrid; Trilling, Mirko; Horn, Susanne; Schilling, Bastian; Schadendorf, Dirk; Griewank, Klaus; Paschen, Annette
    Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesions
    In: Nature Communications Jg. 8 (2017) 15440
    Online Volltext: dx.doi.org/ (Open Access)
  • Ahci, Müberra; Stempelmann, Karin; Buttkereit, Ulrike; Crivello, Pietro; Trilling, Mirko; Heinold, Andreas; Steckel, Nina Kristin; Koldehoff, Michael; Horn, Peter; Beelen, Dietrich; Fleischhauer, Katharina
    Clinical utility of quantitative PCR for chimerism and engraftment monitoring after allogeneic stem cell transplantation for hematologic malignancies
    In: Biology of Blood and Marrow Transplantation Jg. 23 (2017) Nr. 10, S. 1658 - 1668
    Online Volltext: dx.doi.org/
  • Megger, Dominik A; Philipp, Jos; Le-Trilling, Vu Thuy Khanh; Sitek, Barbara; Trilling, Mirko
    Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.
    In: Frontiers in Immunology Jg. 14 (2017) Nr. 8, 1139
    Online Volltext: dx.doi.org/ (Open Access)
  • Guberina, H.; Silva, F. D.; Michita, R. T.; Dolff, Sebastian; Bienholz, A.; Heinemann, Falko M.; Wilde, Benjamin; Trilling, Mirko; Horn, Peter; Kribben, Andreas; Witzke, Oliver; Rebmann, Vera
    HLA-E Allelic Genotype Impacts on Occurrence of CMV Infection After Living Renal Transplantation
    In: Transplant International Jg. 30 (2017) Nr. Suppl. 4 SI, S. 7 Abstract V024
    Online Volltext: dx.doi.org/
  • Grosche, Linda; Draßner, Christina; Mühl-Zürbes, Petra; Kamm, Lisa; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Steinkasserer, Alexander; Heilingloh, Christiane S.
    Human cytomegalovirus-induced degradation of CYTIP modulates dendritic cell adhesion and migration
    In: Frontiers in Immunology Jg. 8 (2017) 461
    Online Volltext: dx.doi.org/ (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture system
    In: PLoS ONE Jg. 12 (2017) Nr. 3, e0174695
    Online Volltext: dx.doi.org/ (Open Access)
  • Guberina, Hana; Michita, Rafael Tomoya; Dolff, Sebastian; Bienholz, Anja; Trilling, Mirko; Heinemann, Falko M.; Horn, Peter; Kribben, Andreas; Witzke, Oliver; Rebmann, Vera
    Recipient HLA-G +3142 CC genotype and concentrations of soluble HLA-G impact on occurrence of CMV infection after living-donor kidney transplantation
    In: International Journal of Molecular Sciences (IJMS) Jg. 18 (2017) Nr. 11, S. 2338
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schupp, Anna-Kathrin; Trilling, Mirko; Rattay, Stephanie; Le-Trilling, Vu Thuy Khanh; Haselow, Katrin; Stindt, Jan; Zimmermann, Albert; Häussinger, Dieter; Hengel, Hartmut; Graf, Dirk
    Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in Hepatocytes
    In: Journal of Virology Jg. 90 (2016) Nr. 15, S. 6686 - 6698
    Online Volltext: dx.doi.org/ (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Megger, Dominik A.; Katschinski, Benjamin; Landsberg, Christine D.; Rückborn, Meike U.; Tao, Sha; Krawczyk, Adalbert; Bayer, Wibke; Drexler, Ingo; Tenbusch, Matthias; Sitek, Barbara; Trilling, Mirko
    Broad and potent antiviral activity of the NAE inhibitor MLN4924
    In: Scientific Reports Jg. 6 (2016) 19977
    Online Volltext: dx.doi.org/ (Open Access)
  • Shaabani, Namir; Duhan, Vikas; Khairnar, Vishal; Gassa, Asmae; Ferrer-Tur, Rita; Häussinger, Dieter; Recher, Mike; Zelinskyy, Gennadiy; Liu, Jia; Dittmer, Ulf; Trilling, Mirko; Scheu, Stefanie; Hardt, Cornelia; Lang, Philipp A; Honke, Nadine; Lang, Karl S.
    CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection
    In: Cell Death and Disease Jg. 7 (2016) Nr. 11, e2446
    Online Volltext: dx.doi.org/ (Open Access)
  • Corrales-Aguilar, Eugenia; Trilling, Mirko; Reinhard, Henrike; Falcone, Valeria; Zimmermann, Albert; Adams, Ortwin; Santibanez, Sabine; Hengel, Hartmut
    Highly individual patterns of virus-immune IgG effector responses in humans
    In: Medical Microbiology and Immunology Jg. 205 (2016) Nr. 5, S. 409 - 424
    Online Volltext: dx.doi.org/ (Open Access)
  • Lavender, Kerry J.; Gibbert, Kathrin; Peterson, Karin E.; Van Dis, Erik; Francois, Sandra; Woods, Tyson; Messer, Ronald J.; Gawanbacht, Ali; Müller, Janis A.; Münch, Jan; Phillips, Katie; Race, Brent; Harper, Michael S.; Guo, Kejun; Lee, Eric J.; Trilling, Mirko; Hengel, Hartmut; Piehler, Jacob; Verheyen, Jens; Wilson, Cara C.; Santiago, Mario L.; Hasenkrug, Kim J.; Dittmer, Ulf
    Interferon alpha subtype-specific suppression of HIV-1 infection in vivo
    In: Journal of Virology Jg. 90 (2016) Nr. 13, S. 6001 - 6013
    Online Volltext: dx.doi.org/ (Open Access)
  • Ehlting, Christian; Trilling, Mirko; Tiedje, Christopher; Le-Trilling, Vu Thuy Khanh; Albrecht, Ute; Kluge, Stefanie; Zimmermann, Albert; Graf, Dirk; Gaestel, Matthias; Hengel, Hartmut; Häussinger, Dieter; Bode, Johannes Georg
    MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infections
    In: Journal of Hepatology Jg. 64 (2016) Nr. 2, S. 380 - 389
    Online Volltext: dx.doi.org/
  • Donnarumma, Tiziano; Young, George R; Merkenschlager, Julia; Eksmond, Urszula; Bongard, Nadine; Nutt, Stephen L; Boyer, Claude; Dittmer, Ulf; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Bayer, Wibke; Kassiotis, George
    Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus
    In: Cell Reports Jg. 17 (2016) Nr. 6, S. 1571 - 1583
    Online Volltext: dx.doi.org/ (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Attack, parry and riposte : Molecular fencing between the innate immune system and human herpesviruses
    In: Tissue Antigens Jg. 86 (2015) Nr. 1, S. 1 - 13
    Online Volltext: dx.doi.org/
  • Wu, Weimin; Dietze, Kirsten; Gibbert, Kathrin; Lang, Karl S.; Trilling, Mirko; Yan, Huimin; Wu, Jun; Yang, Dongliang; Lu, Mengji; Roggendorf, Michael; Dittmer, Ulf; Liu, Jia
    TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infection
    In: Scientific Reports Jg. 5 (2015) 10501
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rattay, Stephanie; Trilling, Mirko; Megger, Dominik A.; Sitek, Barbara; Meyer, Helmut E.; Hengel, Hartmut; Le-Trilling, Vu Thuy Khanh
    The canonical immediate early 3 gene product pIE611 of mouse cytomegalovirus is dispensable for viral replication but mediates transcriptional and posttranscriptional regulation of viral gene products
    In: Journal of Virology Jg. 89 (2015) Nr. 16, S. 8590 - 8598
    Online Volltext: dx.doi.org/ (Open Access)
  • Tirosh, Osnat; Cohen, Yifat; Shitrit, Alina; Shani, Odem; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Friedlander, Gilgi; Tanenbaum, Marvin; Stern-Ginossar, Noam
    The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactions
    In: PLoS Pathogens Jg. 11 (2015) Nr. 11, e1005288
    Online Volltext: dx.doi.org/ (Open Access)
  • Trilling, Mirko; Le, Vu Thuy Khanh; Rashidi-Alavijeh, Jassin; Katschinski, Benjamin; Scheller, Jürgen; Rose-John, Stefan; Androsiac, Gabriela Elena; Jonjic, Stipan; Poli, Valeria; Pfeffer, Klaus; Hengel, Hartmut
    "Activated" STAT proteins : a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells
    In: The Journal of Immunology (JI) Jg. 192 (2014) Nr. 1, S. 447 - 458
    Online Volltext: dx.doi.org/ (Open Access)
  • Corrales-Aguilar, Eugenia; Trilling, Mirko; Hunold, Katja; Fiedler, Manuela; Le, Vu Thuy Khanh; Reinhard, Henrike; Ehrhardt, Katrin; Mercé-Maldonado, Eva; Aliyev, Enver; Zimmermann, Albert; Johnson, David C; Hengel, Hartmut
    Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III
    In: PLoS Pathogens Jg. 10 (2014) Nr. 5, e1004131
    Online Volltext: dx.doi.org/ (Open Access)
  • Keil, Eric; Finkenstädt, David; Wufka, Christian; Trilling, Mirko; Liebfried, Pia; Strobl, Birgit; Müller, Mathias; Pfeffer, Klaus
    Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation
    In: Blood Jg. 123 (2014) Nr. 4, S. 520 - 529
    Online Volltext: dx.doi.org/
  • Döring, Marius; Lessin, Irina; Frenz, Theresa; Spanier, Julia; Kessler, Annett; Tegtmeyer, Pia; Daǧ, Franziska; Thiel, Nadine; Trilling, Mirko; Lienenklaus, Stefan; Weiß, Siegfried B.; Scheu, Stefanie; Messerle, Martin; Čičin-Šain, Luka; Hengel, Hartmut; Kalinke, Ulrich
    M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells
    In: Journal of Virology Jg. 88 (2014) Nr. 23, S. 13638 - 13650
    Online Volltext: dx.doi.org/
  • Corrales-Aguilar, Eugenia; Trilling, Mirko; Reinhard, Henrike; Mercé-Maldonado, Eva; Widera, Marek; Schaal, Heiner; Zimmermann, Albert; Mandelboim, Ofer; Hengel, Hartmut
    A novel assay for detecting virus-specific antibodies triggering activation of Fcγ receptors
    In: Journal of Immunological Methods Jg. 387 (2013) Nr. 1-2, S. 21 - 35
    Online Volltext: dx.doi.org/
  • Manzke, Nora; Akhmetzyanova, Ilseyar; Hasenkrug, Kim J.; Trilling, Mirko; Zelinskyy, Gennadiy; Dittmer, Ulf
    CD4⁺ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8⁺ T cells
    In: Journal of Virology Jg. 87 (2013) Nr. 11, S. 6306 - 6313
    Online Volltext: dx.doi.org/ Online Volltext
  • Bayer, Wibke; Trilling, Mirko; Timm, Jörg; Dittmer, Ulf
    Das überlistete Immunsystem : Viren tricksen das Immunsystem aus, um chronische Infektionen zu etablieren
    In: Unikate: Berichte aus Forschung und Lehre (2013) Nr. 44: Medizin : 50 Jahre Universitätsklinikum Essen, S. 32 - 41
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schleker, Sylvia; Trilling, Mirko
    Data-warehousing of protein-protein interactions indicates that pathogens preferentially target hub and bottleneck proteins
    In: Frontiers in Microbiology Jg. 4 (2013) S. 51
    Online Volltext: dx.doi.org/
  • Trilling, Mirko; Bellora, Nicolás; Rutkowski, Andrzej J.; De Graaf, Miranda; Dickinson, Paul; Robertson, Kevin; Prazeres Da Costa, Olivia; Ghazal, Peter; Friedel, Caroline C.; Albà, M. Mar; Dölken, Lars
    Deciphering the modulation of gene expression by type i and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis
    In: Nucleic Acids Research Jg. 41 (2013) Nr. 17, S. 8107 - 8125
    Online Volltext: dx.doi.org/ (Open Access)
  • Honke, Nadine; Shaabani, Namir; Cadeddu, Giuseppe; Sorg, Ursula R.; Zhang, Dong-Er; Trilling, Mirko; Klingel, Karin; Sauter, Martina; Kandolf, Reinhard; Gailus, Nicole; Van Rooijen, Nico; Burkart, Christoph; Baldus, Stephan E.; Grusdat, Melanie; Löhning, Max; Hengel, Hartmut; Pfeffer, Klaus; Tanaka, Masato; Häussinger, Dieter; Recher, Mike; Lang, Philipp A.; Lang, Karl S.
    Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus
    In: Nature Immunology Jg. 13 (2012) Nr. 1, S. 51 - 57
    Online Volltext: dx.doi.org/
  • Gibbert, Kathrin; Joedicke, Jara J.; Meryk, Andreas; Trilling, Mirko; Francois, Sandra; Duppach, Janine; Kraft, Anke; Lang, Karl S.; Dittmer, Ulf
    Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral Infection
    In: PLoS Pathogens Jg. 8 (2012) Nr. 8, S. e1002868
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Trilling, Mirko; Le, Vu Thuy Khanh; Hengel, Hartmut
    Interplay between CMVs and interferon signaling : Implications for pathogenesis and therapeutic intervention
    In: Future Microbiology Jg. 7 (2012) Nr. 11, S. 1269 - 1282
    Online Volltext: dx.doi.org/

    • Abstracts

  • Schoeler, Lara; Le-Trilling, Vu Thuy Khanh; Dittmer, Ulf; Esser, Stefan; Trilling, Mirko; HIV HEART AGEING Study;
    Analyses of defined human cytomegalovirus-specific antibody effector functions in people living with human immunodeficiency virus
    DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,
    In: HIV Medicine Jg. 24 (2023) Nr. 1, S. 48 - 49
  • Schmidt, Teresa; Rohn, Hana; Trilling, Mirko; Agkatsev, Sarina; Oster, Christoph; Kleinschnitz, Christoph; Sure, Ulrich; Stuschke, Martin; Scheffler, Björn; Kebir, Sied; Glas, Martin
    Immunogenicity of an additional dose of covid-19 vaccine in fully vaccinated patients with glioma to evaluate new national vaccination guidelines : a prospective cohort study
    In: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v63 - v64
    Online Volltext: dx.doi.org/
  • Betke, Luisa; Crivello, Pietro; Maassen, Fabienne; Schuler, Corinna; Arrieta-Bolaños, Thuja; Arrieta-Bolaños, Esteban; Doelken, Lars; Erhard, Florian; Trilling, Mirko; Fleischhauer, Katharina;
    HLA-DP-restricted immunity to human cytomegalovirus is directed against a variety of viral proteins, and modulated by its 84-87 DEAV/GGPM polymorphism
    Joint 35th European Immunogenetics and Histocompatibility Conference; May 17–20, 2022; Amsterdam, the Netherlands,
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 99 (2022) Nr. 5, SI, S. 427 - 428
  • Thier, B.; Such, L.; Peller, V.; Schwamborn, M.; Sucker, A.; Coch, C.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Zhao, F.; Paschen, Annette;
    Interferon-independent enhancement of melanoma cell immunogenicity by RIG-I activation
    47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF) Virtual, March 04‐06, 2021,
    In: Experimental Dermatology Jg. 30 (2021) Nr. 3, S. E78
  • Thier, B.; Such, L.; Schwamborn, M.; Sucker, A.; Coch, C.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Zhao, F.; Paschen, Annette
    RIG-I activation enhances melanoma immunogenicity and improves anti-tumor T cell responses in combination with anti-PD-1 immune checkpoint blocking antibodies
    In: Journal for ImmunoTherapy of Cancer Jg. 8 (2020) Nr. Suppl. 2, S. A3
    Online Volltext: dx.doi.org/ (Open Access)
  • Thier, Beatrice; Such, Lina; Sucker, Antje; Coch, Carla; Hartmann, G.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Zhao, F.; Paschen, Annette
    Tumorzell‐intrinsiche Aktivierung des Immunrezeptors RIG‐I in Kombination mit Immun‐Checkpoint‐Blockade verbessert anti‐Tumor T‐Zellantworten
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 18 (2020) Nr. Suppl. 2: Special Issue: Abstractband anlässlich des 30. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 09.–12. September 2020, S. FV18
    Online Volltext: dx.doi.org/ (Open Access)
  • Leserer, Saskia; Bayraktar, Erva; Tsachakis-Mück, Nikolaus; Koldehoff, Michael; Trilling, Mirko; Fleischhauer, Katharina; Beelen, Dietrich; Turki, Amin T.;
    Cytomegalovirus reactivation kinetics as predictors of survival and relapse after allogeneic cell transplantation for hematologic malignancies
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Supplement 4: Abstracts, S. 203
    Online Volltext: dx.doi.org/ (Open Access)
  • Guberina, H.; Nardi, F. D.; Michita, R. T.; Dolff, Sebastian; Gackler, A.; Heinemann, Falko M.; Wilde, Benjamin; Trilling, Mirko; Horn, Peter; Kribben, Andreas; Witzke, Oliver; Rebmann, Vera
    Impact of HLA-E*01:03 allele carrier status and NKG2C allele deletion on the risk of CMV infection after renal transplantation
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 91 (2018) Nr. 5, S. 345 - 345
    Online Volltext: dx.doi.org/
  • Beelen, Dietrich; Bujor, L. V.; Stempelmann, K.; Fiedler, Melanie; Crivello, P.; Trilling, Mirko; Dittmer, Ulf; Ditschkowski, Markus; Fleischhauer, Katharina
    Early Replication of Human Cytomegalovirus (HCMV) is associated with a reduced risk of hematologic relapse in myeloid neoplasias after matched Unrelated Stem Cell Transplantation (HSCT) in an anti-thymocyte-globuline dependent manner
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 312 - 313
    Online Volltext: dx.doi.org/
  • Francois, Sandra; Berendes, Christopher; Trilling, Mirko; Dittmer, Ulf; Piehler, Jacob; Gibbert, Kathrin
    Antiviral and immunomodulatory activity of different human interferon-α subtypes during chronic viral infections
    In: Cytokine Jg. 63 (2013) Nr. 3, S. 262 - 263
    Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/

    • Poster / Posterbeiträge

  • Pfeifer, Kai Robin; Ebel, Jana-Fabienne; Trilling, Mirko; Le-Trilling, Vu Thuy Khanh; Westendorf, Astrid;
    Cytomegalovirus infection aggravates intestinal inflammation during colitis and impairs the convalescence of the intestinal niche
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 354
    Online Volltext: dx.doi.org/ (Open Access)
  • Rohn, Hana; Lang, Cordula; Schramm, Sabine; Heinemann, Falko M.; Trilling, Mirko; Gäckler, Anja; Witzke, Oliver; Horn, Peter A.; Rebmann, Vera;
    The influence of HLA-G5 on expression of differentiation markers on splenic B cells
    Joint 35th European Immunogenetics and Histocompatibility Conference; May 17–20, 2022; Amsterdam, the Netherlands,
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 99 (2022) Nr. 5, SI, S. 547 - 548
  • Grosche, L.; Drassner, C.; Muehl-Zuerbes, P.; Kamm, L.; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Steinkasserer, A.; Heilingloh, C.;
    Human cytomegalovirus interferes with dendritic cell adhesion and migration via the proteasomal degradation of the cytohesin-1 interacting protein
    15th International Symposium on Dendritic Cells, 10–14 June 2018, Aachen, Germany,
    In: European Journal of Immunology Jg. 48 (2018) Nr. Suppl. 1, S. 103 - 104
    Online Volltext: dx.doi.org/ (Open Access)