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Aktuelle Veranstaltungen
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2023 WS
Vergangene Veranstaltungen (max. 10)
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2023 SS
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Mitarbeiterseminar in englischer Sprache (Immunologie)
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2022 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Age-related changes of the human splenic marginal zone B cell compartmentIn: Immunology Letters Jg. 256-257 (2023) S. 59 - 65ISSN: 1879-0542; 0165-2478Online Volltext: dx.doi.org/
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Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's diseaseIn: Alzheimer's & Dementia (2023) in pressISSN: 1552-5279; 1552-5260Online Volltext: dx.doi.org/ (Open Access)
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The inhibitory receptor Siglec-G controls the severity of chronic lymphocytic leukemiaIn: EMBO Reports Jg. 24 (2023) Nr. 8,ISSN: 1469-3178; 1469-221XOnline Volltext: dx.doi.org/ (Open Access)
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The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B CellsIn: Frontiers in Immunology Jg. 13 (2022)ISSN: 1664-3224Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Effects of a Multimerized Recombinant Autoantibody Against Amyloid-βIn: Neuroscience Jg. 463 (2021) S. 355 - 369ISSN: 0306-4522; 1873-7544Online Volltext: dx.doi.org/
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Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamicsIn: The Journal of Immunology (JI) Jg. 206 (2021) Nr. 12, S. 2839 - 2851ISSN: 1550-6606; 0022-1767; 1047-7381; 1048-3233Online Volltext: dx.doi.org/ (Open Access)
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MARCKS affects cell motility and response to BTK inhibitors in CLLIn: Blood Jg. 138 (2021) Nr. 7, S. 544 - 556ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout lifeIn: Journal of Experimental Medicine (JEM) Jg. 218 (2021) Nr. 4, S. e20201952ISSN: 1540-9538; 0022-1007Online Volltext: dx.doi.org/ (Open Access)
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Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLLIn: Genome Medicine Jg. 12 (2020) Nr. 1,ISSN: 1756-994XOnline Volltext: dx.doi.org/ (Open Access)
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Human CD30⁺ B cells represent a unique subset related to Hodgkin lymphoma cellsIn: The Journal of Clinical Investigation (JCI) Jg. 128 (2018) Nr. 7, S. 2996 - 3007ISSN: 1558-8238; 0021-9738Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Jg. 13 (2017) Nr. 1,ISSN: 1553-734X; 1553-7358Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemiaIn: Nature Genetics Jg. 48 (2016) Nr. 3, S. 253 - 264ISSN: 1061-4036; 1546-1718Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Dissection of CD20 regulation in lymphoma using RNAiIn: Leukemia Jg. 30 (2016) Nr. 12, S. 2409 - 2412ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemiaIn: International Journal of Cancer Jg. 138 (2016) Nr. 1, S. 121 - 124ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/ (Open Access)
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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5281 - E5289ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ (Open Access)
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Functional capacities of human igm memory b cells in early inflammatory responses and secondary germinal center reactionsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 6, S. E546 - E555ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ (Open Access)
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Progressive Epigenetic Programming during B Cell Maturation Is Reflected in a Continuum of Epigenetic Disease Phenotypes in Chronic Lymphocytic LeukemiaIn: Blood Jg. 126 (2015) Nr. 23, S. 2436ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
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Progressive epigenetic programming during B cell maturation yields a continuum of clonal disease phenotypes with distinct etiologies in chronic lymphocytic leukemiaIn: Clinical Cancer Research Jg. 21 (2015) Nr. 17 Suppl., S. B25 - B25ISSN: 1078-0432Online Volltext: dx.doi.org/
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Recurrent mutation of JAK3 in T-cell prolymphocytic leukemiaIn: Genes, Chromosomes and Cancer Jg. 53 (2014) Nr. 4, S. 309 - 316ISSN: 1098-2264; 1045-2257Online Volltext: dx.doi.org/
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Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 196ISSN: 0378-584X; 1423-0240
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Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivoIn: Cancer Cell Jg. 23 (2013) Nr. 1, S. 77 - 92ISSN: 1535-6108; 1878-3686Online Volltext: dx.doi.org/ (Open Access)
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Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genesIn: Leukemia Jg. 26 (2012) Nr. 1, S. 185 - 188ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/
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Cellular origin and pathophysiology of chronic lymphocytic leukemiaIn: Journal of Experimental Medicine (JEM) Jg. 209 (2012) Nr. 12, S. 2183 - 2198ISSN: 1540-9538; 0022-1007Online Volltext: dx.doi.org/ (Open Access)
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Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)In: Blood Jg. 120 (2012) Nr. 21, S. 3512ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/
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Telomeres and prognosis in patients with chronic lymphocytic leukaemiaIn: International Journal of Hematology Jg. 93 (2011) Nr. 1, S. 74 - 82ISSN: 1865-3774Online Volltext: dx.doi.org/
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Single-Cell Multi-Omic and Spatial Analysis of Nodal B Cell Non-Hodgkin Lymphomas Reveals Plasticity in B Cell Maturation As a Driver of Intratumor Heterogeneity
64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH): DEC 10-13, 2022; New Orleans, USA,In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 752 - 753ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ (Open Access) -
Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL
60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,In: Blood Jg. 132 (2018) Nr. Supplement 1: 60th ASH Annual Meeting Abstracts, S. 3885 - 3885ISSN: 1528-0020; 0006-4971Online Volltext: dx.doi.org/ (Open Access) -
Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B CellsIn: Scandinavian Journal of Immunology Jg. 80 (2014) Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233ISSN: 0300-9475; 1365-3083Online Volltext: dx.doi.org/
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Origin and Pathogenesis of B Cell LymphomasIn: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.) 2019, S. 1 - 33ISBN: 978-1-4939-9150-1; 978-1-4939-9151-8Online Volltext: dx.doi.org/
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Determining the Origin of Human Germinal Center B Cell-Derived MalignanciesIn: Germinal Centers: Methods and Protocols / Calado, Dinis Pedro (Hrsg.) 2017, S. 253 - 279ISBN: 978-1-4939-7094-0; 978-1-4939-7095-7Online Volltext: dx.doi.org/
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Origin and Pathogenesis of B Cell LymphomasIn: Lymphoma: Methods and Protocols 2013, S. 1 - 25ISBN: 978-1-62703-268-1; 978-1-62703-269-8 ISSN: 1064-3745Online Volltext: dx.doi.org/
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Molekulare Analyse von humanen Gedächtnis-B-Zell-PopulationenDuisburg, Essen (2010) 178 Bl.