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Dr. rer. nat. Marc Seifert

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Kibler, Artur; Seifert, Marc; Budeus, Bettina
    Age-related changes of the human splenic marginal zone B cell compartment
    In: Immunology Letters, Jg. 256-257, 2023, S. 59 – 65
    DOI
  • Kronimus, Yannick; Albus, Alexandra; Hasenberg, Mike; Walkenfort, Bernd; Seifert, Marc; Budeus, Bettina; Gronewold, Janine; Hermann, Dirk M.; Ross, J. Alexander; Lochnit, Günter; Galuska, Sebastian P.; Marcus, Katrin; Sitek, Barbara; Klotsche, Jens; Mengel, David; Neumann, Sascha; Dodel, Richard
    Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's disease
    In: Alzheimer's & Dementia, Jg. 19, 2023, Nr. 12, S. 5563 – 5572
    DOI (Open Access)
  • Röder, Bettina; Fahnenstiel, Hannah; Schäfer, Simon; Budeus, Bettina; Dampmann, Maria; Eichhorn, Melanie; Angermüller, Sieglinde; Brost, Claudia; Winkler, Thomas H; Seifert, Marc; Nitschke, Lars
    The inhibitory receptor Siglec-G controls the severity of chronic lymphocytic leukemia
    In: EMBO Reports, Jg. 24, 2023, Nr. 8, e56420
    DOI (Open Access)
  • Kibler, Artur; Budeus, Bettina; Küppers, Ralf; Seifert, Marc
    The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells
    In: Frontiers in Immunology, Jg. 13, 2022, 825619
    DOI, Online Volltext (Open Access)
  • Albus, Alexandra; Kronimus, Yannick; Neumann, Christine; Vidovic, Natascha; Frenzel, André; Kuhn, Philipp; Seifert, Marc; Ziehm, Tamar; van der Wurp, Hendrik; Dodel, Richard
    Effects of a Multimerized Recombinant Autoantibody Against Amyloid-β
    In: Neuroscience, Jg. 463, 2021, S. 355 – 369
    DOI
  • Budeus, Bettina; Kibler, Artur; Brauser, Martina; Homp, Ekaterina; Bronischewski, Kevin; Ross, J. Alexander; Görgens, Andre; Weniger, Marc; Dunst, Josefine; Kreslavsky, Taras; da Conceição Castro, Symone Vitoriano; Murke, Florian; Oakes, Christopher C.; Rusch, Peter; Andrikos, Dimitrios; Kern, Peter; Köninger, Angela; Lindemann, Monika; Johansson, Patricia; Hansen, Wiebke; Lundell, Anna-Carin; Rudin, Anna; Dürig, Jan; Giebel, Bernd; Hoffmann, Daniel; Küppers, Ralf; Seifert, Marc
    Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamics
    In: The Journal of Immunology (JI), Jg. 206, 2021, Nr. 12, S. 2839 – 2851
    DOI
  • Beckmann, Laura; Berg, Valeska; Dickhut, Clarissa; Sun, Clare; Merkel, Olaf; Bloehdorn, Johannes; Robrecht, Sandra; Seifert, Marc; da Palma Guerreiro, Alexandra; Claasen, Julia; Loroch, Stefan; Oliverio, Matteo; Underbayev, Chingiz; Vaughn, Lauren; Thomalla, Daniel; Hülsemann, Malte F.; Tausch, Eugen; Fischer, Kirsten; Fink, Anna Maria; Eichhorst, Barbara; Sickmann, Albert; Wendtner, Clemens M.; Stilgenbauer, Stephan; Hallek, Michael; Wiestner, Adrian; Zahedi, René P.; Frenzel, Lukas P.
    MARCKS affects cell motility and response to BTK inhibitors in CLL
    In: Blood, Jg. 138, 2021, Nr. 7, S. 544 – 556
    DOI, Online Volltext (Open Access)
  • Kibler, Artur; Budeus, Bettina; Homp, Ekaterina; Bronischewski, Kevin; Berg, Victoria; Sellmann, Ludger; Murke, Florian; Heinold, Andreas; Heinemann, Falko M.; Lindemann, Monika; Bekeredjian-Ding, Isabelle; Horn, Peter; Kirschning, Carsten Jürgen; Küppers, Ralf; Seifert, Marc
    Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life
    In: Journal of Experimental Medicine (JEM), Jg. 218, 2021, Nr. 4, S. e20201952
    DOI (Open Access)
  • Wierzbinska, Justyna A.; Toth, Reka; Ishaque, Naveed; Rippe, Karsten; Mallm, Jan-Philipp; Klett, Lara C.; Mertens, Daniel; Zenz, Thorsten; Hielscher, Thomas; Seifert, Marc; Küppers, Ralf; Assenov, Yassen; Lutsik, Pavlo; Stilgenbauer, Stephan; Roessner, Philipp M.; Seiffert, Martina; Byrd, John; Oakes, Christopher C.; Plass, Christoph; Lipka, Daniel B.
    Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL
    In: Genome Medicine, Jg. 12, 2020, Nr. 1, 29
    DOI (Open Access)
  • Weniger, Marc; Tiacci, Enrico; Schneider, Stefanie; Arnolds, Judith; Rüschenbaum, Sabrina; Duppach, Janine; Seifert, Marc; Döring, Claudia; Hansmann, Martin-Leo; Küppers, Ralf
    Human CD30⁺ B cells represent a unique subset related to Hodgkin lymphoma cells
    In: The Journal of Clinical Investigation (JCI), Jg. 128, 2018, Nr. 7, S. 2996 – 3007
    DOI, Online Volltext (Open Access)
  • Saeedghalati, Mohammadkarim; Farahpour, Farnoush; Budeus, Bettina; Lange, Anja; Westendorf, Astrid; Seifert, Marc; Küppers, Ralf; Hoffmann, Daniel
    Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to Microbiomes
    In: PLoS Computational Biology, Jg. 13, 2017, Nr. 1, e1005362
    DOI, Online Volltext (Open Access)
  • Oakes, Christopher C; Seifert, Marc; Assenov, Yassen; Gu, Lei; Przekopowitz, Martina; Ruppert, Amy S; Wang, Qi; Imbusch, Charles D; Serva, Andrius; Koser, Sandra D; Brocks, David; Lipka, Daniel B; Bogatyrova, Olga; Weichenhan, Dieter; Brors, Benedikt; Rassenti, Laura; Kipps, Thomas J; Mertens, Daniel; Zapatka, Marc; Lichter, Peter; Döhner, Hartmut; Küppers, Ralf; Zenz, Thorsten; Stilgenbauer, Stephan; Byrd, John C; Plass, Christoph
    DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
    In: Nature Genetics, Jg. 48, 2016, Nr. 3, S. 253 – 264
    DOI, Online Volltext (Open Access)
  • Slabicki, M; Lee, K S; Jethwa, A; Sellner, L; Sacco, F; Walther, T; Hüllein, J; Dietrich, S; Wu, B; Lipka, D B; Oakes, C C; Mamidi, S; Pyrzynska, B; Winiarska, M; Oles, M; Seifert, Marc; Plass, C; Kirschfink, M; Boettcher, M; Gollab, J; Huber, W; Fröhling, S; Zenz, T
    Dissection of CD20 regulation in lymphoma using RNAi
    In: Leukemia, Jg. 30, 2016, Nr. 12, S. 2409 – 2412
    DOI
  • Johansson, Patricia; Bergmann, Anke; Rahmann, Sven; Wohlers, Inken; Scholtysik, René; Przekopowitz, Martina; Seifert, Marc; Tschurtschenthaler, Gertraud; Webersinke, Gerald; Jäger, Ulrich; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia
    In: International Journal of Cancer, Jg. 138, 2016, Nr. 1, S. 121 – 124
    DOI (Open Access)
  • Khairnar, Vishal; Duhan, Vikas; Kumar Maney, Sathish; Seifert, Marc; Kirschning, Carsten; Westendorf, Astrid M.; Dittmer, Ulf; Küppers, Ralf; Scheffrahn, Inka; Göthert, Joachim R.; Singer, Bernhard B.; Lang, Karl S.; et al.
    CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
    In: Nature Communications, Jg. 6, 2015, 6217
    DOI (Open Access)
  • Budeus, Bettina; De Reynoso, Stefanie Schweigle; Przekopowitz, Martina; Hoffmann, Daniel; Seifert, Marc; Küppers, Ralf
    Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 112, 2015, Nr. 38, S. E5281 – E5289
    DOI (Open Access)
  • Seifert, Marc; Przekopowitz, Martina; Taudien, Sarah; Lollies, Anna; Ronge, Viola; Drees, Britta; Lindemann, Monika; Hillen, Uwe; Engler, Harald; Singer, Bernhard B.; Küppers, Ralf
    Functional capacities of human igm memory b cells in early inflammatory responses and secondary germinal center reactions
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 112, 2015, Nr. 6, S. E546 – E555
    DOI (Open Access)
  • Oakes, C. C.; Seifert, Marc; Assenov, Y.; Gu, L.; Przekopowitz, M.; Ruppert, A. S.; Wang, Q.; Imbusch, C.; Serva, A.; Koser, S.; Brocks, D.; Lipka, D. B.; Bogatyrova, O.; Brors, B.; Weichenhan, D.; Rassenti, L. Z.; Kipps, T. J.; Mertens, D.; Zapatka, M.; Lichter, P.; Dohner, H.; Küppers, Ralf; Zenz, T.; Stilgenbauer, S.; Byrd, J. C.; Plass, C.
    Progressive Epigenetic Programming during B Cell Maturation Is Reflected in a Continuum of Epigenetic Disease Phenotypes in Chronic Lymphocytic Leukemia
    In: Blood, Jg. 126, 2015, Nr. 23, S. 2436
    DOI
  • Lipka, Daniel; Mertens, Daniel; Ruppert, Amy; Bogatyrova, Olga; Seifert, Marc; Plass, Christoph; Zenz, Thorsten; Stilgenbauer, Stephan; Yassen, Assenov; Küppers, Ralf; Koser, Sandra; Gu, Lei; Doehner, Hartmut; Zapatka, Marc; Oakes, Christopher C.; Byrd, John; Serva, Andrius; Brocks, David; Lichter, Peter; Przekopowitz, Martina
    Progressive epigenetic programming during B cell maturation yields a continuum of clonal disease phenotypes with distinct etiologies in chronic lymphocytic leukemia
    In: Clinical Cancer Research, Jg. 21, 2015, Nr. 17 Suppl., S. B25 – B25
    DOI
  • Bergmann, Anke K; Schneppenheim, Sina; Seifert, Marc; Betts, Matthew J; Haake, Andrea; Lopez, Cristina; Maria Murga Penas, Eva; Vater, Inga; Jayne, Sandrine; Dyer, Martin J S; Schrappe, Martin; Dührsen, Ulrich; Ammerpohl, Ole; Russell, Robert B; Küppers, Ralf; Dürig, Jan; Siebert, Reiner
    Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia
    In: Genes, Chromosomes and Cancer, Jg. 53, 2014, Nr. 4, S. 309 – 316
    DOI
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, R.; Seifert, Marc; Jäger, Ursula; Tschurtschenthaler, G.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Onkologie, Jg. 36, 2013, Nr. Suppl. 7, S. 196
  • Lutzny, Gloria; Kocher, Thomas; Schmidt-Supprian, Marc; Rudelius, Martina; Klein-Hitpaß, Ludger; Finch, Andrew J; Dürig, Jan; Wagner, Michaela; Haferlach, Claudia; Kohlmann, Alexander; Schnittger, Susanne; Seifert, Marc; Wanninger, Stefan; Zaborsky, Nadja; Oostendorp, Robert; Ruland, Jürgen; Leitges, Michael; Kuhnt, Toni; Schäfer, Yvonne; Lampl, Benedikt; Peschel, Christian; Egle, Alexander; Ringshausen, Ingo
    Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo
    In: Cancer Cell, Jg. 23, 2013, Nr. 1, S. 77 – 92
    DOI (Open Access)
  • Ammerpohl, O; Haake, A; Pellissery, S; Giefing, M; Richter, J; Balint, B; Kulis, M; Le, J; Bibikova, M; Drexler, H G; Seifert, Marc; Shaknovic, R; Korn, B; Küppers, Ralf; Martín-Subero, J I; Siebert, R
    Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes
    In: Leukemia, Jg. 26, 2012, Nr. 1, S. 185 – 188
    DOI
  • Seifert, Marc; Sellmann, Ludger; Bloehdorn, Johannes; Wein, Frederik; Stilgenbauer, Stephan; Dürig, Jan; Küppers, Ralf
    Cellular origin and pathophysiology of chronic lymphocytic leukemia
    In: Journal of Experimental Medicine (JEM), Jg. 209, 2012, Nr. 12, S. 2183 – 2198
    DOI (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, René; Seifert, Marc; Jäger, Ulrich; Tschurtschenthaler, Gertraud; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Blood, Jg. 120, 2012, Nr. 21, S. 3512
    DOI
  • Sellmann, Ludger; Röth, Alexander; Baerlocher, Gabriela M.; Küppers, Ralf; Siemer, Dörte; Seifert, Marc; Dürig, Jan; Dührsen, Ulrich; Nückel, Holger; Opalka, Bertram; Bartels, Marius; de Beer, Dirk
    Telomeres and prognosis in patients with chronic lymphocytic leukaemia
    In: International Journal of Hematology, Jg. 93, 2011, Nr. 1, S. 74 – 82
    DOI

    • Abstracts

  • Parker, Helen; Mirandari, Amatta; Jaramillo-Oquendo, Carolina; Duran-Ferrer, Marti; Stevens, Ben; Buermann, Lara; Amarasinghe, Harindra Eranthi; Thomas, Jaya; Carr, Louise J.; Syeda, Shama; Sakthipakan, Methusha; Parry, Marina; Davies, Zadie; McIver-Brown, Neil; Xochelli, Aliki; Ennis, Sarah; Scarfo, Lydia; Ghia, Paolo; Kalpadakis, Christina H.; Pangalis, Gerassimos; Rossi, Davide; Wagner, Simon; Ahearne, Matthew; Seifert, Marc; Plass, Christoph; Weichenhan, Dieter; Kimby, Eva; Sutton, Lesley Ann; Rosenquist, Richard; Forconi, Francesco; Stamatopoulos, Kostas; Salido, Marta; Ferrer, Ana; Thieblemont, Catherine; Oscier, David Graham; Walewska, Renata; Rose-Zerilli, Matthew JJ; Gibson, Jane; Martin Subero, Iñaki I.; Oakes, Christopher C.; Bryant, Dean J.; Strefford, Jonathan C.
    The Proliferative History Index, Epicmit, Derived from Genome-Wide Epigenomic Profiling, Is a Key Driver of Clinical Survival in Splenic Marginal Zone Lymphoma
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 4370 – 4370
    DOI (Open Access)
  • Fitzgerald, Donnacha; Roider, Tobias; Baertsch, Marc-A.; Vöhringer, Harald; Knoll, Mareike; Budeus, Bettina; Kibler, Artur; Mathioudaki, Anna; Caillé, Léandra; Li, Linsha; Mammen, Johannes; Seifert, Marc; Huber, Wolfgang; Dietrich, Sascha
    Single-Cell Multi-Omic and Spatial Analysis of Nodal B Cell Non-Hodgkin Lymphomas Reveals Plasticity in B Cell Maturation As a Driver of Intratumor Heterogeneity
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1: 64th ASH Annual Meeting and Exposition, 10-13 December 2022, New Orleans, S. 752 – 753
    DOI (Open Access)
  • Wierzbinska, Justyna Anna; Toth, Reka; Ishaque, Naveed; Mallm, Jan-Phillip; Rippe, Karsten; Mertens, Daniel; Hielscher, Thomas; Zenz, Thorsten; Seifert, Marc; Küppers, Ralf; Assenov, Yassen; Stilgenbauer, Stephan; Byrd, John C.; Oakes, Christopher C.; Lipka, Daniel B.; Plass, Christoph
    Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1: 60th ASH Annual Meeting Abstracts, S. 3885 – 3885
    DOI (Open Access)
  • Seifert, Marc; Przekopowitz, Martina; Schweigle, Stefanie; Budeus, Bettina; Taudien, Sarah; Lollies, Anna; Ronge, Viola; Sellmann, Ludger; Hillen, Uwe; Engler, Harald; Schedlowski, Manfred; Singer, Bernhard B.; Hoffmann, Daniel; Küppers, Ralf
    Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B Cells
    In: Scandinavian Journal of Immunology: Wiley-Blackwell, Jg. 80, 2014, Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233
    DOI

    • Beiträge in Sammelwerken und Tagungsbänden

  • Weniger, Marc A.; Seifert, Marc; Küppers, Ralf
    B Cell Differentiation and the Origin and Pathogenesis of Human B Cell Lymphomas
    In: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.). New York: Humana, 2025, S. 1 – 30
    DOI
  • Seifert, Marc; Scholtysik, René; Küppers, Ralf
    Origin and Pathogenesis of B Cell Lymphomas
    In: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.). New York: Springer, 2019, S. 1 – 33
    DOI
  • Seifert, Marc; Küppers, Ralf
    Determining the Origin of Human Germinal Center B Cell-Derived Malignancies
    In: Germinal Centers: Methods and Protocols / Calado, Dinis Pedro (Hrsg.). New York: Springer, 2017, S. 253 – 279
    DOI
  • Seifert, Marc; Scholtysik, René; Küppers, Ralf
    Origin and Pathogenesis of B Cell Lymphomas
    In: Lymphoma: Methods and Protocols. New York [u.a]: Humana Press, 2013, S. 1 – 25
    DOI

    • Dissertation

  • Seifert, Marc
    Molekulare Analyse von humanen Gedächtnis-B-Zell-Populationen
    Duisburg, Essen, 2010
    Online Volltext, Online Volltext

    • Poster / Posterbeiträge

  • Jehn, Lutz-Bernhard; Berg, Victoria; Kibler, Artur; Boerner, Eda; Waelscher, Julia; Budeus, Bettina; Seifert, Marc; Taube, Christian; Bonella, Francesco
    Flow cytometric evaluation of whole lung lavage (WLL) fluid from patients with pulmonary alveolar proteinosis (PAP) : preliminary findings
    International Congress of the European Respiratory Society (ERS) 2023 ; 9 - 13 September 2023, Milan, Italy,
    In: European Respiratory Journal (ERJ). Sheffield: European Respiratory Society, Jg. 62, 2023, Nr. Supplement 67: ERS International Congress 2023 abstracts, PA3946
    DOI