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Dr. rer. nat. Gennadiy Zelinskyy

Funktionen

  • Wissenschaftliche/r Mitarbeiter/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Stupia, Simone; Heeke, Christina; Brüggemann, Alicia; Zaremba-Montenari, Anne; Thier, Beatrice; Kretz, Julia; Sucker, Antje; Philip, Manuel; Zelinskyy, Gennadiy; Ferrone, Soldano; Rösch, Alexander; Horn, Susanne; Hadaschik, Eva; Schadendorf, Dirk; Trilling, Mirko; Dittmer, Ulf; Griewank, Klaus; Zhao, Fang; Paschen, Annette
    HLA class II loss and JAK1/2 deficiency coevolve in melanoma leading to CD4 T cell and IFNγ cross-resistance
    In: Clinical Cancer Research , Jg. 29 2023, Nr. 15, S. 2894 – 2907
    DOI
  • Westmeier, Jaana; Brochtrup, Annika; Paniskaki, Krystallenia; Karakoese, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Limmer, Andreas; Mittermüller, Daniela; Liu, Jia; Zheng, Xin; Koval, Tetiana; Kaidashev, Igor; Berger, Marc Moritz; Herbstreit, Frank; Brenner, Thorsten; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients
    In: Frontiers in Immunology , Jg. 14 2023, 1236374
    DOI, Online Volltext (Open Access)
  • Limmer, Andreas; Engler, Andrea; Kattner, Simone; Gregorius, Jonas; Pattberg, Kevin Thomas; Schulz, Rebecca; Schwab, Jansje; Roth, Johannes; Vogl, Thomas; Krawczyk, Adalbert; Witzke, Oliver; Zelinskyy, Gennadiy; Dittmer, Ulf; Brenner, Thorsten; Berger, Marc
    Patients with SARS-CoV-2-Induced Viral Sepsis Simultaneously Show Immune Activation, Impaired Immune Function and a Procoagulatory Disease State
    In: Vaccines , Jg. 11 2023, Nr. 2, 435
    DOI (Open Access)
  • Izmailova, Olga; Shlykova, Oksana; Kabaliei, Alina; Vatsenko, Anastasia; Ivashchenko, Dmytro; Dudchenko, Maksym; Volianskyi, Andrii; Zelinskyy, Gennadiy; Koval, Tetiana; Dittmer, Ulf; Kaidashev, Igor
    Polymorphism of tmprss2 (rs12329760) and severity of COVID-19 in the Ukrainian population : Response
    In: Acta Biomedica , Jg. 94 2023, Nr. 2, e2023109
    DOI
  • Izmailova, Olga; Shlykova, Oksana; Kabaliei, Alina; Vatsenko, Anastasia; Ivashchenko, Dmytro; Dudchenko, Maksym; Volianskyi, Andrii; Zelinskyy, Gennadiy; Koval, Tetiana; Dittmer, Ulf; Kaidashev, Igor
    Polymorphism of tmprss2 (rs12329760) but not ace2 (rs4240157), tmprss11a (rs353163) and cd147 (rs8259) is associated with the severity of COVID-19 in the Ukrainian population
    In: Acta Biomedica , Jg. 94 2023, Nr. 1, e2023030
    DOI (Open Access)
  • Mittermüller, Daniela; Otto, Lucas; Long, Zoë; Kraus, Andreas; Beer, Alexander; Hasenberg, Anja; Zelinskyy, Gennadiy; Westmeier, Jaana; Hasenkrug, Kim J.; Dittmer, Ulf; Gunzer, Matthias
    Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected mice
    In: JCI Insight , Jg. 8 2023, Nr. 13, e167482
    DOI, Online Volltext (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Liu, Jing; Deng, Hui; Yang, Xuecheng; Wang, Hua; Feng, Xuemei; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Wang, Baoju; Yang, Dongliang; Zheng, Xin; Liu, Jia
    SARS-CoV-2-specific T cell responses wane profoundly in convalescent individuals 10 months after primary infection
    In: Virologica Sinica , Jg. 38 2023, Nr. 4, S. 606 – 619
    DOI (Open Access)
  • David, Paul; Westmeier, Jaana; Drabczyk-Pluta, Malgorzata; Werner, Tanja; Ickler, Julia; Francois, Sandra; Bayer, Wibke; Sutter, Kathrin; Del Rio, Maria Luisa; Rodriguez-Barbosa, Jose-Ignacio; Dittmer, Ulf; Zelinskyy, Gennadiy
    The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell Responses
    In: Frontiers in Virology , Jg. 2 2022, 836291
    DOI, Online Volltext (Open Access)
  • Knuschke, Torben; Kollenda, Sebastian; Wenzek, Christina; Zelinskyy, Gennadiy; Steinbach, Philine; Dittmer, Ulf; Buer, Jan; Epple, Matthias; Westendorf, Astrid
    A combination of anti-pd-l1 treatment and therapeutic vaccination facilitates improved retroviral clearance via reactivation of highly exhausted t cells
    In: mBio , Jg. 12 2021, Nr. 1, S. e02121 – 20
    DOI (Open Access)
  • Liu, Jia; Yang, Xuecheng; Wang, Hua; Li, Ziwei; Deng, Hui; Liu, Jing; Xiong, Shue; He, Junyi; Feng, Xuemei; Guo, Chunxia; Wang, Weixian; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Senff, Tina; Menne, Christopher; Timm, Jörg; Zhang, Yanfang; Deng, Fei; Lu, Yinping; Wu, Jun; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Wang, Baoju; Zheng, Xin
    Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairment
    In: mBio , Jg. 12 2021, Nr. 2, S. e00085 – 21
    DOI (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Deng, Hui; Wang, Hua; Feng, Xuemei; Quan, Xufeng; Wang, Xiaoyan; Li, Sumeng; Lu, Sihong; Yang, Xuecheng; Wang, Baoju; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Zheng, Xin; Liu, Jia
    Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World Setting
    In: Frontiers in Immunology , Jg. 12 2021, 802858
    DOI (Open Access)
  • David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A.; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D.; Tenbusch, Matthias; Dietze, Kirsten; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S.; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid; Dittmer, Ulf; Zelinskyy, Gennadiy
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
    In: PLoS Pathogens , Jg. 16 2020, Nr. 3, e1008340
    DOI (Open Access)
  • Rodriguez-Barbosa, Jose-Ignacio; Azuma, Miyuki; Zelinskyy, Gennadiy; Perez-Simon, Jose-Antonio; del Rio, Maria-Luisa
    Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model
    In: Cancer Immunology, Immunotherapy 2020
    DOI (Open Access)
  • Cassetta, Luca; Bruderek, Kirsten; Skrzeczynska-Moncznik, Joanna; Osiecka, Oktawia; Hu, Xiaoying; Rundgren, Ida Marie; Lin, Ang; Santegoets, Kim; Horzum, Utku; Godinho-Santos, Ana; Zelinskyy, Gennadiy; Garcia-Tellez, Thalia; Bjelica, Sunčica; Taciak, Bartłomiej; Kittang, Astrid Olsnes; Höing, Benedikt; Lang, Stephan; Dixon, Michael; Müller, Verena; Utikal, Jochen Sven; Karakoç, Derya; Yilmaz, Kerim Bora; Górka, Emilia; Bodnar, Lubomir; Anastasiou, Olympia Evdoxia; Bourgeois, Christine; Badura, Robert; Kapinska-Mrowiecka, Monika; Gotic, Mirjana; Ter Laan, Mark; Kers-Rebel, Esther; Król, Magdalena; Santibañez, Juan Francisco; Müller-Trutwin, Michaela; Dittmer, Ulf; De Sousa, Ana Espada; Esendaǧli, Güneş; Adema, Gosse; Loré, Karin; Ersvær, Elisabeth; Umansky, Viktor; Pollard, Jeffrey W.; Cichy, Joanna; Brandau, Sven
    Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation
    In: Journal for ImmunoTherapy of Cancer , Jg. 8 2020, Nr. 2, S. e001223
    DOI (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Erratum for Westmeier et al., "Impaired Cytotoxic CD8⁺ T Cell Response in Elderly COVID-19 Patients"
    In: mBio , Jg. 11 2020, Nr. 5, S. 02243 – 02220
    DOI (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Impaired cytotoxic CD8⁺ T cell response in elderly COVID-19 patients
    In: mBio , Jg. 11 2020, Nr. 5, S. e02243 – 20
    DOI (Open Access)
  • Gu, Chenjian; Ming, Lijun; Fang, Yili; Liu, Xuejing; Zhang, Junqi; Zelinskyy, Gennadiy; Deng, Qiang; Liu, Jing; Xie, Youhua
    Restriction of exogenous DNA expression by SAMHD1
    In: Science Bulletin , Jg. 65 2020, Nr. 7, S. 573 – 586
    DOI
  • Dittmer, Ulf; Sutter, Kathrin; Kassiotis, George; Zelinskyy, Gennadiy; Bánki, Zoltán; Stoiber, Heribert; Santiago, Mario L.; Hasenkrug, Kim J.
    Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity
    In: FEMS Microbiology Reviews , Jg. 43 2019, Nr. 5, S. 435 – 456
    DOI (Open Access)
  • Dorhoi, Anca; Glaría, Estibaliz; Garcia-Tellez, Thalia; Nieuwenhuizen, Natalie E.; Zelinskyy, Gennadiy; Favier, Benoit; Singh, Anurag; Ehrchen, Jan; Gujer, Cornelia; Münz, Christian; Saraiva, Margarida; Sohrabi, Yahya; Sousa, Ana E.; Delputte, Peter; Müller-Trutwin, Michaela; Valledor, Annabel F.
    MDSCs in infectious diseases: regulation, roles, and readjustment
    In: Cancer Immunology, Immunotherapy , Jg. 68 2019, Nr. 4, S. 673 – 685
    DOI (Open Access)
  • David, Paul; Megger, Dominik A.; Kaiser, Tamara; Werner, Tanja; Liu, Jia; Chen, Lieping; Sitek, Barbara; Dittmer, Ulf; Zelinskyy, Gennadiy
    The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8⁺ T Cells During an Acute Retroviral Infection
    In: Frontiers in Immunology , Jg. 10 2019, 54
    DOI (Open Access)
  • Khairnar, Vishal; Duhan, Vikas; Patil, Ashwini M.; Zhou, Fan; Bhat, Hilal; Thoens, Christine; Sharma, Piyush; Adomati, Tom; Friendrich, Sarah-Kim; Bezgovsek, Judith; Dreesen, Janine D.; Wennemuth, Gunther; Westendorf, Astrid; Zelinskyy, Gennadiy; Dittmer, Ulf; Hardt, Cornelia; Timm, Jörg; Göthert, Joachim Rudolf; Lang, Philipp A.; Singer, Bernhard B.; Lang, Karl S.
    CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infection
    In: Nature Communications , Jg. 9 2018, 2561
    DOI (Open Access)
  • Otto, Lucas; Zelinskyy, Gennadiy; Schuster, Marc; Dittmer, Ulf; Gunzer, Matthias
    Imaging of cytotoxic antiviral immunity while considering the 3R principle of animal research
    In: Journal of Molecular Medicine , Jg. 96 2018, Nr. 3-4, S. 349 – 360
    DOI
  • Klein, Johanna C.; Moses, Katrin; Zelinskyy, Gennadiy; Sody, Simon; Buer, Jan; Lang, Stephan; Helfrich, Iris; Dittmer, Ulf; Kirschning, Carsten Jürgen; Brandau, Sven
    Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth
    In: Nature Communications , Jg. 8 2017, S. 14600
    DOI (Open Access)
  • Teigler, Jeffrey E.; Zelinskyy, Gennadiy; Eller, Michael A.; Bolton, Diane L.; Marovich, Mary; Gordon, Alexander D.; Alrubayyi, Aljawharah; Alter, Galit; Robb, Merlin L.; Martin, Jeffrey N.; Deeks, Steven G.; Michael, Nelson L.; Dittmer, Ulf; Streeck, Hendrik
    Differential inhibitory receptor expression on T cells delineates functional capacities in chronic viral infection
    In: Journal of Virology , Jg. 91 2017, Nr. 23, S. e01263 – 17
    DOI (Open Access)
  • Malyshkina, Anna; Littwitz-Salomon, Elisabeth; Sutter, Kathrin; Zelinskyy, Gennadiy; Windmann, Sonja; Schimmer, Simone; Paschen, Annette; Streeck, Hendrik; Hasenkrug, Kim J; Dittmer, Ulf
    Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection
    In: Scientific Reports , Jg. 7 2017, S. 7785
    DOI (Open Access)
  • Drabczyk-Pluta, Malgorzata; Werner, Tanja; Hoffmann, Daniel; Leng, Qibin; Chen, Lieping; Dittmer, Ulf; Zelinskyy, Gennadiy
    Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infection
    In: Retrovirology , Jg. 14 2017, 42
    DOI (Open Access)
  • Ma, Zhiyong; Liu, Jia; Wu, Weimin; Zhang, Ejuan; Zhang, Xiaoyong; Li, Qian; Zelinskyy, Gennadiy; Buer, Jan; Dittmer, Ulf; Kirschning, Carsten Jürgen; Lu, Mengji
    The IL-1R/TLR signaling pathway is essential for efficient CD8+ T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model
    In: Cellular & Molecular Immunology , Jg. 14 2017, Nr. 12, S. 997 – 1008
    DOI (Open Access)
  • Akhmetzyanova, Ilseyar; Dittmer, Ulf; Brandau, Sven; Streeck, Hendrik; Dietze, Kirsten; Malyshkina, Anna; Littwitz-Salomon, Elisabeth; Zelinskyy, Gennadiy
    CD137 agonist therapy can reprogram regulatory T cells into cytotoxic CD4+ T cells with antitumor activity
    In: The Journal of Immunology (JI) , Jg. 196 2016, Nr. 1, S. 484 – 492
    DOI (Open Access)
  • Shaabani, Namir; Duhan, Vikas; Khairnar, Vishal; Gassa, Asmae; Ferrer-Tur, Rita; Häussinger, Dieter; Recher, Mike; Zelinskyy, Gennadiy; Liu, Jia; Dittmer, Ulf; Trilling, Mirko; Scheu, Stefanie; Hardt, Cornelia; Lang, Philipp A; Honke, Nadine; Lang, Karl S.
    CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection
    In: Cell Death and Disease , Jg. 7 2016, Nr. 11, e2446
    DOI (Open Access)
  • Akhmetzyanova, Ilseyar; Drabczyk, Malgorzata; Neff, C Preston; Gibbert, Kathrin; Dietze, Kirsten; Werner, Tanja; Liu, Jia; Chen, Lieping; Lang, Karl S.; Palmer, Brent E; Dittmer, Ulf; Zelinskyy, Gennadiy
    Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing
    In: PLoS Pathogens , Jg. 11 2015, Nr. 12, e1005364
    DOI (Open Access)
  • Akhmetzyanova, Ilseyar; Drabczyk, Malgorzata; Neff, C Preston; Gibbert, Kathrin; Dietze, Kirsten; Werner, Tanja; Liu, Jia; Chen, Lieping; Lang, Karl S.; Palmer, Brent E; Dittmer, Ulf; Zelinskyy, Gennadiy
    PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing
    In: PLoS Pathogens , Jg. 11 2015, Nr. 10, e1005224
    DOI (Open Access)
  • Joedicke, Jara J.; Zelinskyy, Gennadiy; Dittmer, Ulf; Hasenkrug, Kim J.
    CD8+ T Cells Are Essential for Controlling Acute Friend Retrovirus Infection in C57BL/6 Mice
    In: Journal of Virology , Jg. 88 2014, Nr. 9, S. 5200 – 5201
    DOI
  • Joedicke, Jara J.; Dietze, Kirsten; Zelinskyy, Gennadiy; Dittmer, Ulf
    The phenotype and activation status of regulatory T cells during Friend retrovirus infection
    In: Virologica Sinica , Jg. 29 2014, Nr. 1, S. 48 – 60
    DOI
  • Manzke, Nora; Akhmetzyanova, Ilseyar; Hasenkrug, Kim J.; Trilling, Mirko; Zelinskyy, Gennadiy; Dittmer, Ulf
    CD4⁺ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8⁺ T cells
    In: Journal of Virology , Jg. 87 2013, Nr. 11, S. 6306 – 6313
    DOI
  • Dietze, Kirsten Katrin; Zelinskyy, Gennadiy; Liu, Jia; Kretschmer, Freya; Schimmer, Simone; Dittmer, Ulf
    Combining Regulatory T Cell Depletion and Inhibitory Receptor Blockade Improves Reactivation of Exhausted Virus-Specific CD8+ T Cells and Efficiently Reduces Chronic Retroviral Loads
    In: PLoS Pathogens , Jg. 9 2013, Nr. 12, S. e1003798
    DOI (Open Access)
  • Zelinskyy, Gennadiy; Werner, Tanja; Dittmer, Ulf
    Natural regulatory T cells inhibit production of cytotoxic molecules in CD8+ T cells during low-level Friend retrovirus infection
    In: Retrovirology , Jg. 10 2013, Nr. 1, 109
    DOI (Open Access)
  • Liu, Jia; Jiang, Min; Ma, Zhiyong; Dietze, Kirsten; Zelinskyy, Gennadiy; Yang, Dongliang; Dittmer, Ulf; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro
    In: The Journal of Immunology (JI) , Jg. 191 2013, Nr. 12, S. 6178 – 6190
    DOI
  • Akhmetzyanova, Ilseyar; Zelinskyy, Gennadiy; Schimmer, Simone; Brandau, Sven; Altenhoff, Petra; Sparwasser, Tim; Dittmer, Ulf
    Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells
    In: Cancer Immunology, Immunotherapy , Jg. 62 2013, Nr. 2, S. 257 – 271
    DOI
  • Dietze, Kirsten; Zelinskyy, Gennadiy; Gibbert, Kathrin; Schimmer, Simone; Francois, Sandra; Myers, Lara; Sparwasser, Tim; Hasenkrug, Kim J.; Dittmer, Ulf
    Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8⁺ T cells and reduces chronic retroviral set points
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 108 2011, Nr. 6, S. 2420 – 2425
    DOI (Open Access)
  • Zelinskyy, Gennadiy; Myers, Lara; Dietze, Kirsten; Gibbert, Kathrin; Roggendorf, Michael; Liu, Jia; Lu, Mengji; Kraft, Anke R.; Teichgräber, Volker; Hasenkrug, Kim J.; Dittmer, Ulf
    Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication
    In: The Journal of Immunology (JI) , Jg. 187 2011, Nr. 7, S. 3730 – 3737
    DOI
  • Nair, Savita R.; Zelinskyy, Gennadiy; Shimmer, Simone; Gerlach, Nicole; Kassiotis, George; Dittmer, Ulf; Schimmer, S.
    Mechanisms of control of acute Friend virus infection by CD4⁺ T helper cells and their functional impairment by regulatory T cells
    In: Journal of General Virology , Jg. 91 2010, Nr. 2, S. 440 – 451
    DOI
  • Gibbert, Kathrin; Dietze, Kirsten; Zelinskyy, Gennadiy; Lang, Karl S.; Barchet, Winfried; Kirschning, Carsten Jürgen; Dittmer, Ulf
    Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease
    In: The Journal of Immunology (JI) , Jg. 185 2010, Nr. 10, S. 6179 – 6189
    DOI (Open Access)