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Dr. rer. nat. Eva Pastille

Institut für Medizinische Mikrobiologie am Universitätsklinikum Essen

Anschrift
Hufelandstr. 55
45122 Essen
Telefon
0201/723 3069
E-Mail
eva.pastille@uk-essen.de

Funktionen

  • Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Medizinische Mikrobiologie

Aktuelle Veranstaltungen

Keine aktuellen Veranstaltungen.

Vergangene Veranstaltungen (max. 10)

Keine vergangenen Veranstaltungen.

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Teske, K.; Erickson, N.A.; Huck, A.; Dzamukova, M.; Fulde, M.; Heinbokel, T.; Horst, D.; Klymiuk, N.; Pastille, Eva; Mekes-Adamczyk, A.; Löhning, M.; Gruber, A.D.; Glauben, R.; Mundhenk, L.
    The impact of disease and species differences on the intestinal CLCA4 gene expression
    In: Journal of Molecular Medicine, Jg. 103, 2025, Nr. 6, S. 687 – 697
    DOI (Open Access)
  • Pastille, Eva; Konermann, Anna
    Exploring the role of innate lymphoid cells in the periodontium : Insights into immunological dynamics during orthodontic tooth movement
    In: Frontiers in Immunology, Jg. 15, 2024, 1428059
    DOI (Open Access)
  • Steinbach, Philine; Pastille, Eva; Kaumanns, Lara; Adamczyk, Alexandra; Sutter, Kathrin; Hansen, Wiebke; Dittmer, Ulf; Buer, Jan; Westendorf, Astrid M.; Knuschke, Torben
    Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control
    In: PLoS Pathogens, Jg. 20, 2024, Nr. 1, e1011982
    DOI (Open Access)
  • Wenzek, Christina; Siemes, Devon; Hönes, G. Sebastian; Pastille, Eva; Härting, Nina; Kaiser, Frank; Möller, Lars C.; Engel, Daniel R.; Westendorf, Astrid; Führer, Dagmar
    Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice
    In: iScience, Jg. 27, 2024, Nr. 8, 110547
    DOI, Online Volltext (Open Access)
  • Reuter, Sebastian; Raspe, Jonas; Uebner, Hendrik; Contoyannis, Alexandros; Pastille, Eva; Westendorf, Astrid M.; C. Caso, Georgia; Cover, Timothy L.; Müller, Anne; Taube, Christian
    Treatment with Helicobacter pylori-derived VacA attenuates allergic airway disease
    In: Frontiers in Immunology, Jg. 14, 2023, 1092801
    DOI, Online Volltext (Open Access)
  • Adamczyk, Alexandra; Pastille, Eva; Kehrmann, Jan; Vu, Vivian P.; Geffers, Robert; Wasmer, Marie-Hélène; Kasper, Stefan; Schuler, Martin; Lange, Christian; Muggli, Beat; Rau, Tilman T.; Klein, Diana; Hansen, Wiebke; Krebs, Philippe; Buer, Jan; Westendorf, Astrid
    GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer
    In: Cancer Research, Jg. 81, 2021, Nr. 11, S. 2970 – 2982
    DOI (Open Access)
  • Ngo Thi Phuong, Nhi; Palmieri, Vittoria; Adamczyk, Alexandra; Klopfleisch, Robert; Langhorst, Jost; Hansen, Wiebke; Westendorf, Astrid; Pastille, Eva
    IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute Colitis
    In: Frontiers in Immunology, Jg. 12, 2021, 669787
    DOI, Online Volltext (Open Access)
  • Pastille, Eva; Faßnacht, Tabea; Adamczyk, Alexandra; Ngo Thi Phuong, Nhi; Buer, Jan; Westendorf, Astrid
    Inhibition of TLR4 Signaling Impedes Tumor Growth in Colitis-Associated Colon Cancer
    In: Frontiers in Immunology, Jg. 12, 2021, 669747
    DOI, Online Volltext (Open Access)
  • Palmieri, Vittoria; Ebel, Jana-Fabienne; Ngo Thi Phuong, Nhi; Klopfleisch, Robert; Vu, Vivian Pham; Adamczyk, Alexandra; Zöller, Julia; Riedel, Christian; Buer, Jan; Krebs, Philippe; Hansen, Wiebke; Pastille, Eva; Westendorf, Astrid M.
    Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity
    In: Mucosal Immunology, Jg. 14, 2021, Nr. 4, S. 923 – 936
    DOI (Open Access)
  • David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A.; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D.; Tenbusch, Matthias; Dietze, Kirsten; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S.; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid; Dittmer, Ulf; Zelinskyy, Gennadiy
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
    In: PLoS Pathogens, Jg. 16, 2020, Nr. 3, e1008340
    DOI (Open Access)
  • Kehrmann, Jan; Effenberg, Laura; Wilk, Camilla; Schoemer, Davina; Ngo Thi Phuong, Nhi; Adamczyk, Alexandra; Pastille, Eva; Scholtysik, René; Klein-Hitpaß, Ludger; Klopfleisch, Robert; Westendorf, Astrid; Buer, Jan
    Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome
    In: Immunology, Jg. 159, 2020, Nr. 3, S. 344 – 353
    DOI (Open Access)
  • Heße, Carolin; Kollenda, Sebastian; Rotan, Olga; Pastille, Eva; Adamczyk, Alexandra; Wenzek, Christina; Hansen, Wiebke; Epple, Matthias; Buer, Jan; Westendorf, Astrid; Knuschke, Torben
    A tumor-peptide–based nanoparticle vaccine elicits efficient tumor growth control in antitumor immunotherapy
    In: Molecular Cancer Therapeutics, Jg. 18, 2019, Nr. 6, S. 1069 – 1080
    DOI (Open Access)
  • Thiel, Jacqueline; Alter, Christina; Luppus, Sina; Eckstein, Anja; Tan, Susanne; Führer, Dagmar; Pastille, Eva; Westendorf, Astrid; Buer, Jan; Hansen, Wiebke
    MicroRNA-183 and microRNA-96 are associated with autoimmune responses by regulating T cell activation
    In: Journal of Autoimmunity, Jg. 96, 2019, S. 94 – 103
    DOI
  • Pastille, Eva; Wasmer, Marie-Hélène; Adamczyk, Alexandra; Vu, Vivian P.; Mager, Lukas F.; Phuong, Nhi Ngo Thi; Palmieri, Vittoria; Simillion, Cedric; Hansen, Wiebke; Kasper, Stefan; Schuler, Martin; Muggli, Beat; McCoy, Kathy D.; Buer, Jan; Zlobec, Inti; Westendorf, Astrid; Krebs, Philippe
    The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer
    In: Mucosal Immunology, Jg. 12, 2019, Nr. 4, S. 990 – 1003
    DOI (Open Access)
  • Adamczyk, Alexandra; Gageik, Daniel; Frede, Annika; Pastille, Eva; Hansen, Wiebke; Rueffer, Andreas; Buer, Jan; Büning, Jürgen; Langhorst, Jost; Westendorf, Astrid
    Differential expression of GPR15 on T cells during ulcerative colitis
    In: JCI Insight, Jg. 2, 2017, Nr. 8, e90585
    DOI (Open Access)
  • Pastille, Eva; Frede, A.; Adamczyk, A.; McSorley, H.; Maizels, R.; Buer, Jan; Westendorf, Astrid
    Helminth-induced intestinal inflammation facilitates tumor growth and progression in colitis-associated colon cancer
    47th Annual meeting [of the] German Society of Immunology (DGfI), 15.–17.09.2017, Erlangen,
    In: European Journal of Immunology, Jg. 47, 2017, Nr. S2: 47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 67
    DOI
  • Westendorf, Astrid; Skibbe, Kathrin; Adamczyk, Alexandra; Buer, Jan; Geffers, Robert; Hansen, Wiebke; Pastille, Eva; Jendrossek, Verena
    Hypoxia enhances immunosuppression by inhibiting CD4+ Effector T cell function and promoting treg activity
    In: Cellular Physiology and Biochemistry, Jg. 41, 2017, Nr. 4, S. 1271 – 1284
    DOI (Open Access)
  • Pastille, Eva; Frede, Annika; McSorley, Henry J.; Gräb, Jessica; Adamczyk, Alexandra; Kollenda, Sebastian; Hansen, Wiebke; Epple, Matthias; Buer, Jan; Maizels, Rick M.; Klopfleisch, Robert; Westendorf, Astrid
    Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer
    In: PLoS Pathogens, Jg. 13, 2017, Nr. 9, e1006649
    DOI (Open Access)
  • Smirnov, Anna; Pohlmann, Stephanie; Nehring, Melanie; Ali, Shafaqat; Mann-Nüttel, Ritu; Scheu, Stefanie; Antoni, Anne-Charlotte; Hansen, Wiebke; Büettner, Manuela; Gardiasch, Miriam J.; Westendorf, Astrid; Wirsdörfer, Florian; Pastille, Eva; Dudda, Marcel; Flohe, Stefanie
    Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression
    In: Frontiers in Immunology, Jg. 8, 2017, 1622
    DOI (Open Access)
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Pastille, Eva; Schmitz, Daniel; Flohé, Sascha; Schumak, Beatrix; Flohe, Stefanie
    Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge
    In: PLoS ONE, Jg. 11, 2016, Nr. 5, S. e0155870
    DOI (Open Access)
  • Wadwa, Munisch-Kumar; Klopfleisch, R; Adamczyk, A; Frede, A; Pastille, Eva; Mahnke, K; Hansen, Wiebke; Geffers, R; Lang, Karl S.; Buer, Jan; Büning, J; Westendorf, Astrid
    IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sites
    In: Mucosal Immunology, Jg. 9, 2016, Nr. 5, S. 1263 – 1277
    DOI (Open Access)
  • Pastille, Eva; Pohlmann, Stephanie; Wirsdörfer, Florian; Reib, Anna; Flohe, Stefanie
    A disturbed interaction with accessory cells upon opportunistic infection with Pseudomonas aeruginosa contributes to an impaired IFN-γ production of NK cells in the lung during sepsis-induced immunosuppression
    In: Innate Immunity, Jg. 21, 2015, Nr. 2, S. 115 – 126
    DOI
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Pastille, Eva; Hansen, Wiebke; Flohe, Stefanie
    Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice
    In: Clinical Science, Jg. 128, 2015, Nr. 11, S. 825 – 838
    DOI (Open Access)
  • Tatura, Roman; Zeschnigk, Michael; Hansen, Wiebke; Steinmann, Jörg; Goncalves Vidigal, Pedrina; Hutzler, Marina; Pastille, Eva; Westendorf, Astrid; Buer, Jan; Kehrmann, Jan
    Relevance of Foxp3+ regulatory T cells for early and late phases of murine sepsis
    In: Immunology, Jg. 146, 2015, Nr. 1, S. 144 – 156
    DOI (Open Access)
  • Langhorst, Jost; Frede, Annika; Knott, Markus; Pastille, Eva; Buer, Jan; Dobos, Gustav; Westendorf, Astrid
    Distinct Kinetics in the Frequency of Peripheral CD4+ T Cells in Patients with Ulcerative Colitis Experiencing a Flare during Treatment with Mesalazine or with a Herbal Preparation of Myrrh, Chamomile, and Coffee Charcoal
    In: PLoS ONE, Jg. 9, 2014, Nr. 8, e104257
    DOI (Open Access)
  • De Haan, Jacco Juri; Pastille, Eva; Wirsdörfer, Florian; Lubbers, Tim; Greve, Jan Willem M; Zhang, Yang; Buurman, Wim A.; Flohe, Stefanie
    Lipid-rich enteral nutrition improves the defense against an opportunistic infection during polymicrobial sepsis
    In: Shock, Jg. 41, 2014, Nr. 2, S. 109 – 114
    DOI
  • Pastille, Eva; Bardini, Katrin; Fleissner, Diana; Adamczyk, Alexandra; Frede, Annika; Wadwa, Munisch; Smolinski, Dorthe von; Kasper, Stefan; Sparwasser, Tim; Gruber, Achim D.; Schuler, Martin; Sakaguchi, Shimon; Roers, Axel; Müller, Werner; Hansen, Wiebke; Buer, Jan; Westendorf, Astrid
    Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer
    In: Cancer Research, Jg. 74, 2014, Nr. 16, S. 4258 – 4269
    DOI
  • Pastille, Eva; Didovic, Sonja; Brauckmann, Daniela; Rani, Meenakshi; Agrawal, Hemant; Schade, Fritz Ulrich; Zhang, Yang; Flohe, Stefanie
    Modulation of Dendritic Cell Differentiation in the Bone Marrow Mediates Sustained Immunosuppression after Polymicrobial Sepsis
    In: The Journal of Immunology (JI), Jg. 186, 2011, Nr. 2, S. 977 – 986
    DOI

    • Abstracts

  • Raspe, Jonas; Schmitz, M; Übner, H; Westendorf, Astrid; Pastille, Eva; Cover, T; Müller, A; Taube, Christian; Reuter, S
    Das vakuolsisierende Zytotoxin (VacA) reduziert Atemwegsinflammation, Mukusproduktion und subepitheliale Fibrose in einem therapeutischen Modell
    63. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V.,
    In: Pneumologie. Stuttgart: Thieme, Jg. 77, 2023, Nr. S 01, S. S62
    DOI
  • Schoemer, D.; Adamczyk, A.; Pastille, Eva; Westendorf, Astrid; Buer, Jan; Kehrmann, Jan
    Analysis of the gut microbiome in Foxp3+Regulatory T cell depleted mice
    47th Annual meeting [of the] German Society of Immunology (DGfI), 15.–17.09.2017, Erlangen,
    In: European Journal of Immunology. Hoboken: Wiley, Jg. 47, 2017, Nr. S2: 47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 212
    DOI (Open Access)
  • Pastille, Eva; Zhang, Yang; Kroell, Nadine; Bak, Michaela; Schade, Fritz Ulrich; Flohe, Stefanie
    Systemic infection alters differentiation of dendritic cells in the bone marrow and mediates chronic dendritic cell dysfunction
    8th World Congress on Trauma, Shock, Inflammation and Sepsis – TSIS 2010 – March 9th-13th, 2010, Munich, Germany,
    In: Inflammation Research. Cham; Basel; Boston; Berlin; Heidelberg [u.a.]: Springer, Jg. 59 Suppl., 2010, S. S20 – S21
    DOI