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Honorarprofessor/in, Mikrobiologie I
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 bindingIn: The EMBO Journal (2023) in pressISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/ (Open Access)
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The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint ComplexIn: Nature Communications Jg. 14 (2023) Nr. 1,ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
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Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and DynactinIn: The Journal of Cell Biology (JCB) Jg. 221 (2022) Nr. 11,ISSN: 1540-8140; 0021-9525Online Volltext: dx.doi.org/ (Open Access)
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JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transportIn: The Journal of Cell Biology (JCB) Jg. 221 (2022) Nr. 8,ISSN: 1540-8140; 0021-9525Online Volltext: dx.doi.org/
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On the role of phase separation in the biogenesis of membraneless compartmentsIn: The EMBO Journal Jg. 41 (2022) Nr. 5,ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/ (Open Access)
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Phosphorylation tunes elongation propensity and cohesiveness of INCENP's intrinsically disordered region : Phosphorylation of INCENP disordered regionIn: Journal of Molecular Biology (JMB) Jg. 434 (2022) Nr. 1,ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/
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Reconstitution and use of highly active human CDK1 : Cyclin-B:CKS1 complexesIn: Protein Science Jg. 31 (2022) Nr. 2, S. 528 - 537ISSN: 1469-896X; 0961-8368Online Volltext: dx.doi.org/ (Open Access)
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Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochoresIn: The EMBO Journal (2022)ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Structure of the human inner kinetochore CCAN complex and its significance for human centromere organizationIn: Molecular Cell Jg. 82 (2022) Nr. 11, S. 2113 - 2131.e8ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access)
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Assembly principles and stoichiometry of a complete human kinetochore moduleIn: Science Advances Jg. 7 (2021) Nr. 27,ISSN: 2375-2548Online Volltext: dx.doi.org/ (Open Access)
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BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in MitosisIn: Molecular Cell Jg. 81 (2021) Nr. 1, S. 67 - 87.e9ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access)
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CDC20 assists its catalytic incorporation in the mitotic checkpoint complexIn: Science Jg. 371 (2021) Nr. 6524, S. 67 - 71ISSN: 1095-9203; 0036-8075Online Volltext: dx.doi.org/
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Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilizationIn: Science Advances Jg. 7 (2021) Nr. 3, S. eabc8590ISSN: 2375-2548Online Volltext: dx.doi.org/ (Open Access)
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Targeted substrate loop insertion by VCP/p97 during PP1 complex disassemblyIn: Nature Structural & Molecular Biology Jg. 28 (2021) Nr. 12, S. 964 - 971ISSN: 1545-9993; 1545-9985Online Volltext: dx.doi.org/
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Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biologyIn: eLife Jg. 8 (2019) S. e48287ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensingIn: Nature Communications Jg. 10 (2019) Nr. 1, S. 4046ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
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Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-couplingIn: eLife Jg. 8 (2019) S. e49539ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosisIn: Nature Cell Biology Jg. 20 (2018) S. 800 - 810ISSN: 1476-4679; 1465-7392Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80.In: Molecular Cell Jg. 71 (2018) Nr. 6, S. 923 - 939.e10ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access)
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Simplified Protocol for Cross-linking Mass Spectrometry Using the MS-Cleavable Cross-linker DSBU with Efficient Cross-link IdentificationIn: Analytical Chemistry Jg. 90 (2018) Nr. 18, S. 10990 - 10999ISSN: 1520-6882; 0003-2700Online Volltext: dx.doi.org/
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The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinasesIn: The Journal of Biological Chemistry (JBC) Jg. 293 (2018) Nr. 26, S. 10084 - 10101ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/ (Open Access)
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Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme FormationIn: Molecular Cell Jg. 72 (2018) Nr. 4, S. 766 - 777ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access)
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A molecular view of kinetochore assembly and functionIn: Biology Jg. 6 (2017) Nr. 1, S. 5ISSN: 2079-7737Online Volltext: dx.doi.org/ (Open Access)
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Basis of catalytic assembly of the mitotic checkpoint complexIn: Nature Jg. 542 (2017) Nr. 7642, S. 498 - 502ISSN: 0028-0836; 1476-4687Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint SignalingIn: Current Biology Jg. 27 (2017) Nr. 19, S. 2915 - 2927.e7ISSN: 1879-0445; 0960-9822Online Volltext: dx.doi.org/ (Open Access)
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CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loadingIn: eLife Jg. 6 (2017) S. e23352ISSN: 2050-084XOnline Volltext: dx.doi.org/ Online Volltext (Open Access)
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Decoding the centromeric nucleosome through CENP-NIn: eLife Jg. 6 (2017) S. e33442ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Structure of the RZZ complex and molecular basis of its interaction with SpindlyIn: The Journal of Cell Biology (JCB) Jg. 216 (2017) Nr. 4, S. 961 - 981ISSN: 1540-8140; 0021-9525Online Volltext: dx.doi.org/ (Open Access)
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The greatest kinetochore show on earthIn: EMBO Reports Jg. 18 (2017) Nr. 9, S. 1473 - 1475ISSN: 1469-3178; 1469-221XOnline Volltext: dx.doi.org/ Online Volltext (Open Access)
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Insights from biochemical reconstitution into the architecture of human kinetochoresIn: Nature Jg. 537 (2016) Nr. 7619, S. 249 - 253ISSN: 0028-0836; 1476-4687Online Volltext: dx.doi.org/
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Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogasterIn: Open Biology Jg. 6 (2016) Nr. 2, S. 150236ISSN: 2046-2441Online Volltext: dx.doi.org/ (Open Access)
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Microtubules : 50 years on from the discovery of tubulinIn: Nature Reviews Molecular Cell Biology Jg. 17 (2016) Nr. 5, S. 322 - 328ISSN: 1471-0080Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Molecular basis of outer kinetochore assembly on CENP-TIn: eLife Jg. 5 (2016) S. e21007ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and AstrinIn: Nature Communications Jg. 7 (2016) S. 11407ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
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Progress in the structural and functional characterization of kinetochoresIn: Current Opinion in Structural Biology Jg. 37 (2016) S. 152 - 163ISSN: 0959-440X; 1879-033XOnline Volltext: dx.doi.org/ (Open Access)
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Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpointIn: Biology Open: BiO Jg. 5 (2016) Nr. 1, S. 11 - 19ISSN: 2046-6390Online Volltext: dx.doi.org/ (Open Access)
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Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human KinetochoresIn: Cell Jg. 167 (2016) Nr. 4, S. 1028 - 1040.e15ISSN: 1097-4172; 0092-8674Online Volltext: dx.doi.org/ (Open Access)
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A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpointIn: eLife Jg. 4 (2015) S. e05269ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochoresIn: The Journal of Cell Biology (JCB) Jg. 210 (2015) Nr. 1, S. 11 - 22ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/ (Open Access)
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Closing the Mad2 cycle : chromosome separation is regulated by a cycle that involves a protein undergoing an unusual topological conversionIn: eLife Jg. 4 (2015) S. e08283ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Complex assembly, crystallization and preliminary x-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complexIn: Acta Crystallographica Section F: Structural Biology and Crystallization Communications Jg. 71 (2015) Nr. 4, S. 438 - 442ISSN: 1744-3091; 2053-230XOnline Volltext: dx.doi.org/ (Open Access)
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DNA-directed assembly of capture tools for constitutional studies of large protein complexesIn: Small Jg. 11 (2015) Nr. 22, S. 2669 - 2674ISSN: 1613-6810; 1613-6829Online Volltext: dx.doi.org/
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HJURP involvement in De Novo CenH3CENP-A and CENP-C recruitmentIn: Cell Reports Jg. 11 (2015) Nr. 1, S. 22 - 32ISSN: 2211-1247Online Volltext: dx.doi.org/ (Open Access)
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Role of intrinsic and extrinsic factors in the regulation of the mitotic checkpoint kinase Bub1In: PLoS ONE Jg. 10 (2015) Nr. 12, S. 0144673ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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The (phospho) needle in the (MELT) haystackIn: Molecular Cell Jg. 57 (2015) Nr. 5, S. 765 - 766ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access)
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The Aurora B kinase in chromosome bi-orientation and spindle checkpoint signalingIn: Frontiers in Oncology Jg. 5 (2015) S. 225ISSN: 2234-943XOnline Volltext: dx.doi.org/ (Open Access)
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The Molecular Biology of Spindle Assembly Checkpoint Signaling DynamicsIn: Current Biology Jg. 25 (2015) Nr. 20, S. R1002 - R1018ISSN: 1879-0445; 0960-9822Online Volltext: dx.doi.org/ (Open Access)
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HORMA domains at the heart of meiotic chromosome dynamicsIn: Developmental Cell Jg. 31 (2014) Nr. 4, S. 389 - 391ISSN: 1534-5807; 1878-1551Online Volltext: dx.doi.org/ (Open Access)
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Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1In: The EMBO Journal Jg. 33 (2014) Nr. 22, S. 2704 - 2720ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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KI motifs of human Knl1 enhance assembly of comprehensive spindle checkpoint complexes around MELT repeatsIn: Current Biology Jg. 24 (2014) Nr. 1, S. 29 - 39ISSN: 1879-0445; 0960-9822Online Volltext: dx.doi.org/ (Open Access)
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Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore OrganizationIn: Molecular Cell Jg. 53 (2014) Nr. 4, S. 591 - 605ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/ (Open Access)
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The pseudo GTPase CENP-M drives human kinetochore assemblyIn: eLife Jg. 3 (2014) S. e02978ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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When Mad met BubIn: EMBO Reports Jg. 15 (2014) Nr. 4, S. 326 - 328ISSN: 1469-3178; 1469-221XOnline Volltext: dx.doi.org/ Online Volltext (Open Access)
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Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingIn: eLife Jg. 2 (2013) S. e01030ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variantIn: Chromosome Research Jg. 21 (2013) Nr. 2, S. 101 - 106ISSN: 1573-6849; 0967-3849Online Volltext: dx.doi.org/
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Loss of survivin influences liver regeneration and is associated with impaired aurora B functionIn: Cell Death and Differentiation Jg. 20 (2013) Nr. 6, S. 834 - 844ISSN: 1350-9047; 1476-5403Online Volltext: dx.doi.org/
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Panta rhei : the APC/C at steady stateIn: The Journal of Cell Biology (JCB) Jg. 201 (2013) Nr. 2, S. 177 - 189ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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The spindle-assembly checkpoint and the beauty of self-destruction : ErratumIn: Nature Structural & Molecular Biology Jg. 20 (2013) Nr. 2, S. 244ISSN: 1545-9993; 1545-9985; 1072-8368Online Volltext: dx.doi.org/
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A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora BIn: The Journal of Cell Biology (JCB) Jg. 199 (2012) Nr. 2, S. 269 - 284ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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Crystal structure of human Aurora B in complex with INCENP and VX-680In: Journal of Medicinal Chemistry Jg. 55 (2012) Nr. 17, S. 7841 - 7848ISSN: 1520-4804; 0022-2623; 1943-2992; 0095-9065Online Volltext: dx.doi.org/ (Open Access)
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Q & A : Andrea MusacchioIn: Current Biology Jg. 22 (2012) Nr. 14, S. R552 - R554ISSN: 1879-0445; 0960-9822Online Volltext: dx.doi.org/
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Role of the Mad2 dimerization interface in the spindle assembly checkpoint independent of kinetochoresIn: Current Biology Jg. 22 (2012) Nr. 20, S. 1900 - 1908ISSN: 1879-0445; 0960-9822Online Volltext: dx.doi.org/
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Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screenIn: ACS Chemical Biology Jg. 7 (2012) Nr. 1, S. 185 - 196ISSN: 1554-8937; 1554-8929Online Volltext: dx.doi.org/
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Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionIn: The Journal of Cell Biology (JCB) Jg. 196 (2012) Nr. 4, S. 451 - 467ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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Structural organization of the kinetochore-microtubule interfaceIn: Current Opinion in Cell Biology Jg. 24 (2012) Nr. 1, S. 48 - 56ISSN: 0955-0674; 1879-0410Online Volltext: dx.doi.org/
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The spindle-assembly checkpoint and the beauty of self-destructionIn: Nature Structural & Molecular Biology Jg. 19 (2012) Nr. 11, S. 1059 - 1061ISSN: 1545-9993; 1545-9985; 1072-8368Online Volltext: dx.doi.org/
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A general framework for inhibitor resistance in protein kinases : ErratumIn: Chemistry and Biology Jg. 18 (2011) Nr. 10, S. 1341ISSN: 1879-1301; 1074-5521Online Volltext: dx.doi.org/
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A general framework for inhibitor resistance in protein kinasesIn: Chemistry and Biology Jg. 18 (2011) Nr. 8, S. 966 - 975ISSN: 1879-1301; 1074-5521Online Volltext: dx.doi.org/
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Abnormal kinetochore-generated pulling forces from expressing a n-terminally modified Hec1In: PLoS ONE Jg. 6 (2011) Nr. 1, S. e16307ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochoreIn: Current biology Jg. 21 (2011) Nr. 5, S. 391 - 398ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correctionIn: The EMBO Journal Jg. 30 (2011) Nr. 8, S. 1508 - 1519ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/
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Homeostatic control of mitotic arrestIn: Molecular cell Jg. 44 (2011) Nr. 5, S. 710 - 720ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/
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Investigating a macromolecular complex : the toolkit of methodsIn: Journal of Structural Biology Jg. 175 (2011) Nr. 2, S. 106 - 112ISSN: 1095-8657; 1047-8477Online Volltext: dx.doi.org/
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Spatial exclusivity combined with positive and negative selection of phosphorylation motifs Is the basis for context-dependent mitotic signalingIn: Science signaling Jg. 4 (2011) Nr. 179, 1-15, art. no. ra42ISSN: 1945-0877; 1525-8882; 1937-9145Online Volltext: dx.doi.org/
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Spindle assembly checkpoint : the third decadeIn: Philosophical transactions of the Royal Society : series B, biological sciences Jg. 366 (2011) Nr. 1584, S. 3595 - 3604ISSN: 0962-8436; 0080-4622; 0264-3839Online Volltext: dx.doi.org/
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Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongationIn: EMBO Reports Jg. 12 (2011) Nr. 4, S. 342 - 349ISSN: 1469-3178; 1469-221XOnline Volltext: dx.doi.org/
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The Ndc80 loop region facilitates formation of kinetochore attachment to the dynamic microtubule plus endIn: Current biology Jg. 21 (2011) Nr. 3, S. 207 - 213ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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Travel notes from the equatorial circleIn: Cell Jg. 146 (2011) Nr. 4, S. 499 - 501ISSN: 0092-8674; 1097-4172Online Volltext: dx.doi.org/
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Cell cycle : deconstructing tensionIn: Current biology Jg. 20 (2010) Nr. 15, S. R634 - R637ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversineIn: The Journal of Cell Biology (JCB) Jg. 190 (2010) Nr. 1, S. 73 - 87ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machineryIn: Structure Jg. 18 (2010) Nr. 5, S. 616 - 626ISSN: 0969-2126; 1878-4186Online Volltext: dx.doi.org/
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Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complexIn: The Journal of Cell Biology (JCB) Jg. 190 (2010) Nr. 1, S. 25 - 34ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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The MIS12 complex is a protein interaction hub for outer kinetochore assemblyIn: The Journal of Cell Biology (JCB) Jg. 190 (2010) Nr. 5, S. 835 - 852ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organizationIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 106 (2009) Nr. 48, S. 20204 - 20209ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/
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Sister chromatid tension and the spindle assembly checkpointIn: Current opinion in cell biology Jg. 21 (2009) Nr. 6, S. 785 - 795ISSN: 0955-0674; 1879-0410Online Volltext: dx.doi.org/
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The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblastsIn: Cell death and differentiation Jg. 16 (2009) Nr. 2, S. 321 - 330ISSN: 1350-9047; 1476-5403Online Volltext: dx.doi.org/
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The life and miracles of kinetochoresIn: The EMBO Journal Jg. 28 (2009) Nr. 17, S. 2511 - 2531ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/
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Discovery of selective aminothiazole aurora kinase inhibitorsIn: ACS Chemical Biology Jg. 3 (2008) Nr. 3, S. 180 - 192ISSN: 1554-8937; 1554-8929Online Volltext: dx.doi.org/
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Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complexIn: Cell Jg. 133 (2008) Nr. 3, S. 427 - 439ISSN: 0092-8674; 1097-4172Online Volltext: dx.doi.org/
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Spindly attachmentsIn: Genes and development Jg. 22 (2008) Nr. 17, S. 2302 - 2307ISSN: 0890-9369; 1549-5477Online Volltext: dx.doi.org/
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The spindle assembly checkpointIn: Current biology Jg. 18 (2008) Nr. 14, S. R591 - R595ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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The spindle assembly checkpoint : correctionIn: Current biology Jg. 18 (2008) Nr. 18, S. 1444ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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MAD contortions : conformational dimerization boosts spindle checkpoint signalingIn: Current opinion in structural biology Jg. 17 (2007) Nr. 6, S. 716 - 725ISSN: 0959-440X; 1879-033XOnline Volltext: dx.doi.org/
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PLK1 inhibitors : setting the mitotic death trapIn: Current biology Jg. 17 (2007) Nr. 8, S. R280 - R283ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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The Mad2 conformational dimer : structure and implications for the spindle assembly checkpointIn: Cell Jg. 131 (2007) Nr. 4, S. 730 - 743ISSN: 0092-8674; 1097-4172Online Volltext: dx.doi.org/
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The Ndc80 complex : hub of kinetochore activityIn: FEBS Letters Jg. 581 (2007) Nr. 15, S. 2862 - 2869ISSN: 0014-5793; 1873-3468Online Volltext: dx.doi.org/
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The spindle-assembly checkpoint in space and timeIn: Nature reviews : molecular cell biology Jg. 8 (2007) Nr. 5, S. 379 - 393ISSN: 1471-0072; 1471-0080Online Volltext: dx.doi.org/
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The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephalyIn: Structure Jg. 15 (2007) Nr. 11, S. 1467 - 1481ISSN: 0969-2126; 1878-4186Online Volltext: dx.doi.org/
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Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiaeIn: The Journal of Cell Biology (JCB) Jg. 174 (2006) Nr. 1, S. 39 - 51ISSN: 0021-9525; 1540-8140Online Volltext: dx.doi.org/
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Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitinIn: Cell Jg. 124 (2006) Nr. 6, S. 1183 - 1195ISSN: 0092-8674; 1097-4172Online Volltext: dx.doi.org/
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Determinants of conformational dimerization of Mad2 and its inhibition by p31cometIn: The EMBO Journal Jg. 25 (2006) Nr. 6, S. 1273 - 1284ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/
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In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamicsIn: Current biology Jg. 16 (2006) Nr. 8, S. 755 - 766ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1In: Cell Jg. 127 (2006) Nr. 5, S. 969 - 982ISSN: 0092-8674; 1097-4172Online Volltext: dx.doi.org/
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Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochoreIn: The Journal of Biological Chemistry (JBC) Jg. 280 (2005) Nr. 32, S. 29088 - 29095ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/
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Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2In: Philosophical transactions of the Royal Society : series B, biological sciences Jg. 360 (2005) Nr. 1455, S. 637 - 648ISSN: 0962-8436; 0080-4622; 0264-3839Online Volltext: dx.doi.org/
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Mechanism of Aurora B activation by INCENP and inhibition by HesperadinIn: Molecular cell Jg. 18 (2005) Nr. 3, S. 379 - 391ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/
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The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpointIn: Current biology Jg. 15 (2005) Nr. 3, S. 214 - 225ISSN: 0960-9822; 1879-0445Online Volltext: dx.doi.org/
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The structural perspective on CDK5In: Neurosignals Jg. 12 (2003) Nr. 4-5, S. 164 - 172ISSN: 1424-862X; 1424-8638Online Volltext: dx.doi.org/
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Crystal structure of the tetrameric Mad1-Mad2 core complex : implications of 'safety belt' binding mechanism for the spindle checkpointIn: The EMBO Journal Jg. 21 (2002) Nr. 10, S. 2496 - 2506ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/
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The spindle checkpoint : structural insights into dynamic signallingIn: Nature reviews : molecular cell biology Jg. 3 (2002) Nr. 10, S. 731 - 741ISSN: 1471-0072; 1471-0080Online Volltext: dx.doi.org/
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Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresIn: The EMBO Journal Jg. 20 (2001) Nr. 23, S. 6648 - 6659ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/
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