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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Metzenmacher, Martin; Váraljai, Renáta; Hegedüs, Balazs; Cima, Igor; Forster, Jan; Schramm, Alexander; Scheffler, Björn; Horn, Peter; Klein, Christoph A.; Szarvas, Tibor; Reis, Hennig; Bielefeld, Nicola; Rösch, Alexander; Aigner, Clemens; Kunzmann, Volker; Wiesweg, Marcel; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.
    Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancer
    In: Cancers Jg. 12 (2020) Nr. 2, S. 353
    ISSN: 2072-6694
  • Schug, Christina; Gupta, Aayush; Urnauer, Sarah; Steiger, Katja; Cheung, Phyllis Fung-Yi; Neander, Christian; Savvatakis, Konstantinos; Schmohl, Kathrin A.; Trajkovic-Arsic, Marija; Schwenk, Nathalie; Schwaiger, Markus; Nelson, Peter J.; Siveke, Jens; Spitzweg, Christine
    A Novel Approach for Image-Guided I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene Delivery
    In: Molecular Cancer Research Jg. 17 (2019) Nr. 1, S. 310 - 320
    ISSN: 1541-7786; 1557-3125
  • Kaissis, Georgios; Ziegelmayer, Sebastian; Lohöfer, Fabian; Steiger, Katja; Algül, Hana; Muckenhuber, Alexander; Yen, Hsi-Yu; Rummeny, Ernst; Friess, Helmut; Schmid, Roland; Weichert, Wilko; Siveke, Jens; Braren, Rickmer
    A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy
    In: PLOS ONE Jg. 14 (2019) Nr. 10, S. e0218642
    ISSN: 1932-6203
  • Kaissis, Georgios; Ziegelmayer, Sebastian; Lohöfer, Fabian; Algül, Hana; Eiber, Matthias; Weichert, Wilko; Schmid, Roland; Friess, Helmut; Rummeny, Ernst; Ankerst, Donna; Siveke, Jens; Braren, Rickmer
    A machine learning model for the prediction of survival and tumor subtype in pancreatic ductal adenocarcinoma from preoperative diffusion-weighted imaging
    In: European Radiology Experimental Jg. 3 (2019) Nr. 1, S. 41
    ISSN: 2509-9280
  • Quambusch, Lena; Landel, Ina; Depta, Laura; Weisner, Jörn; Uhlenbrock, Niklas; Müller, Matthias P.; Glanemann, Franziska; Althoff, Kristina; Siveke, Jens; Rauh, Daniel
    Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity
    In: Angewandte Chemie International Edition Jg. 58 (2019) Nr. 52, S. 18823 - 18829
    ISSN: 1433-7851; 1521-3773
  • Macarulla, Teresa; Blanc, Jean-Frédéric; Wang-Gillam, Andrea; Chen, Li-Tzong; Siveke, Jens; Mirakhur, Beloo; Chen, Jie; Jong, Floris A. de
    Liposomal irinotecan and 5-fluorouracil/leucovorin in older patients with metastatic pancreatic cancer : a subgroup analysis of the pivotal NAPOLI-1 trial
    In: Journal of Geriatric Oncology: cancer and aging research Jg. 10 (2019) Nr. 3, S. 427 - 435
    ISSN: 1879-4076; 1879-4068
  • Walter, Karolin; Tiwary, Kanishka; Trajkovic-Arsic, Marija; Hidalgo-Sastre, Ana; Dierichs, Laura; Liffers, Sven T.; Gu, Jiangning; Gout, Johann; Schulte, Lucas-Alexander; Münch, Jan; Seufferlein, Thomas; Sainz, Bruno; Siveke, Jens; Rodriguez-Aznar, Eva; Hermann, Patrick C.
    MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo
    In: Stem cells international Jg. 2019 (2019) S. 8475389
    ISSN: 1687-966X; 1687-9678
  • Wang-Gillam, Andrea; Hubner, Richard A.; Siveke, Jens T.; Hoff, Daniel D. von; Belanger, Bruce; Jong, Floris A. de; Mirakhur, Beloo; Chen, Li-Tzong
    NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer : Final overall survival analysis and characteristics of long-term survivors
    In: European Journal of Cancer: EJC Jg. 108 (2019) S. 78 - 87
    ISSN: 0959-8049; 1879-0852; 1879-2995
  • Westphalen, C. Benedikt; Preinfalk, A.; Kruger, S.; Haas, M.; Renz, B. W.; Riener, M.-O.; Weber, A.; Kirchner, T.; Werner, J.; Heinemann, V.; Bergwelt-Baildon, M. von; Baba, Hideo Andreas; Siveke, Jens; Ormanns, S.; Boeck, S.
    Neurotrophic tropomyosin receptor kinase (NTRK) and nerve growth factor (NGF) are not expressed in Caucasian patients with biliary tract cancers : pooled data from three independent cohorts
    In: Clinical and Translational Oncology Jg. 21 (2019) Nr. 8, S. 1108 - 1111
    ISSN: 1699-048X; 1699-3055
  • Chen, Li-Tzong; Macarulla, Teresa; Blanc, Jean-Frédéric; Mirakhur, Beloo; Jong, Floris A. de; Belanger, Bruce; Bekaii-Saab, Tanios; Siveke, Jens
    Nomogram for Predicting Survival in Patients Treated with Liposomal Irinotecan Plus Fluorouracil and Leucovorin in Metastatic Pancreatic Cancer
    In: Cancers Jg. 11 (2019) Nr. 8, S. 1068
  • Weisner, Jörn; Landel, Ina; Reintjes, Christoph; Uhlenbrock, Niklas; Trajkovic-Arsic, Marija; Dienstbier, Niklas; Hardick, Julia; Ladigan, Swetlana; Lindemann, Marius; Smith, Steven; Quambusch, Lena; Scheinpflug, Rebekka; Depta, Laura; Gontla, Rajesh; Unger, Anke; Müller, Heiko; Baumann, Matthias; Schultz-Fademrecht, Carsten; Gunther, Georgia; Maghnouj, Abdelouahid; Müller, Matthias P.; Pohl, Michael; Teschendorf, Christian; Wolters, Heiner; Viebahn, Richard; Tannapfel, Andrea; Uhl, Waldemar; Hengstler, Jan G.; Hahn, Stephan A.; Siveke, Jens; Rauh, Daniel
    Preclinical efficacy of covalent-allosteric AKT inhibitor borussertib in combination with trametinib in KRAS-mutant pancreatic and colorectal cancer
    In: Cancer Research: an official organ of the American Association for Cancer Research Jg. 79 (2019) Nr. 9, S. 2367 - 2378
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
  • Hubner, Richard A.; Cubillo, Antonio; Blanc, Jean-Frédéric; Melisi, Davide; Hoff, Daniel D. von; Wang-Gillam, Andrea; Chen, Li-Tzong; Becker, Claus; Mamlouk, Khalid; Belanger, Bruce; Yang, Yoojung; Jong, Floris A. de; Siveke, Jens T.
    Quality of life in metastatic pancreatic cancer patients receiving liposomal irinotecan plus 5-fluorouracil and leucovorin
    In: European Journal of Cancer: EJC Jg. 106 (2019) S. 24 - 33
    ISSN: 0959-8049; 1879-0852
  • Vogel, Felix C. E.; Bordag, Natalie; Zügner, E.; Trajkovic-Arsic, Marija; Chauvistré, Heike; Shannan, Batool; Váraljai, Renáta; Horn, Susanne; Magnes, Christoph; Siveke, Jens; Schadendorf, Dirk; Rösch, Alexander
    Targeting the H3K4 Demethylase KDM5B Reprograms the Metabolome and Phenotype of Melanoma Cells
    In: The Journal of Investigative Dermatology Jg. 139 (2019) Nr. 12, S. 2506 - 2516.e10
    ISSN: 1523-1747; 0022-202X
  • Wieder, Hinrich; Beer, Ambros J.; Siveke, Jens; Schuster, Tibor; Buck, Andreas K.; Herrmann, Ken; Stollfuss, Jens C.
    18F-fluorothymidine PET for predicting survival in patients with resectable pancreatic cancer
    In: Oncotarget Jg. 9 (2018) Nr. 11, S. 10128 - 10134
    ISSN: 1949-2553
  • Schlenk, R.; Barth, T.; Groschel, S.; Heilig, C.; Folprecht, G.; Richter, S.; Mayer-Steinacker, R.; Markus, S.; Moller, P.; Bauer, Sebastian; Siveke, Jens; Dettmer, S.; Richter, D.; Heining, C.; Horak, P.; Jager, D.; Glimm, H.; von Kalle, C.; Frohling, S.
    CDK4/6 inhibition in locally advanced/metastatic chordoma (NCT-PMO-1601)
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 156
    ISSN: 2296-5270
  • ter Veer, Emil; van Rijssen, L Bengt; Besselink, Marc G; Mali, Rosa M A; Berlin, Jordan D; Boeck, Stefan; Bonnetain, Franck; Chau, Ian; Conroy, Thierry; Van Cutsem, Eric; Deplanque, Gael; Friess, Helmut; Glimelius, Bengt; Goldstein, David; Herrmann, Richard; Labianca, Roberto; Van Laethem, Jean-Luc; Macarulla, Teresa; van der Meer, Jonathan H M; Neoptolemos, John P; Okusaka, Takuji; O'Reilly, Eileen M; Pelzer, Uwe; Philip, Philip A; van der Poel, Marcel J; Reni, Michele; Scheithauer, Werner; Siveke, Jens; Verslype, Chris; Busch, Olivier R; Wilmink, Johanna W; van Oijen, Martijn G H; van Laarhoven, Hanneke W M
    Consensus statement on mandatory measurements in pancreatic cancer trials (COMM-PACT) for systemic treatment of unresectable disease
    In: The Lancet Oncology Jg. 19 (2018) Nr. 3, S. e151 - e160
    ISSN: 1470-2045; 1470-2045
  • Lee, K.; Bodoky, G.; Blanc, J.; Siveke, Jens; Mercade, T. M.; Wang-Gillam, A.; Chen, L.; Mirakhur, B.; Chen, J.; de Jong, F.
    Decreased appetite (DA) at baseline impacts prognosis in the NAPOLI-1 phase 3 study in metastatic pancreatic ductal adenocarcinoma (mPDAC)
    In: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 5,
    ISSN: 0923-7534; 1569-8041
  • Haas, Michael; Siveke, Jens; Schenk, Michael; Lerch, Markus M.; Caca, Karel; Freiberg-Richter, Jens; Fischer von Weikersthal, Ludwig; Kullmann, Frank; Reinacher-Schick, Anke C.; Fuchs, Martin; Kanzler, Stefan; Kunzmann, Volker; Ettrich, Thomas J.; Krüger, Stephan; Westphalen, Christoph Benedikt; Held, Swantje; Heinemann, Volker; Boeck, Stefan
    Efficacy of gemcitabine plus erlotinib in rash-positive patients with metastatic pancreatic cancer selected according to eligibility for FOLFIRINOX : A prospective phase II study of the ‘Arbeitsgemeinschaft Internistische Onkologie’
    In: European Journal of Cancer Jg. 94 (2018) S. 95 - 103
    ISSN: 1879-2995; 0959-8049
  • Marks, David L.; Olson, Rachel L.; Urrutia, Raul; Billadeau, Daniel D.; Roy, Nilotpal; Calin, George A.; Fabbri, Muller; Koutsioumpa, Marina; Iliopoulos, Dimitrios; Ordog, Tamas; Huebert, Robert; Sarmento, Olga; Bamidele, Adebowale O.; Faubion, William; Lomberk, Gwen L.; Siveke, Jens; Ahuja, Nita; Iovanna, Juan; Hlady, Ryan A.; Robertson, Keith; Kisiel, John; Pin, Christopher L.; Fernandez-Zapico, Martin E.
    Epigenetics of gastrointestinal diseases : notes from a workshop
    In: Epigenetics Jg. 13 (2018) Nr. 4, S. 449 - 457
    ISSN: 1559-2308; 1559-2294
  • Siveke, Jens
    Fibroblast-activating protein : Targeting the roots of the tumor microenvironment
    In: Journal of Nuclear Medicine Jg. 59 (2018) Nr. 9, S. 1412 - 1414
    ISSN: 1535-5667; 0161-5505
  • Cheung, Phyllis F.; Lutz, Manfred; Siveke, Jens
    Immunotherapy and Combination Strategies in Pancreatic Cancer : Current Status and Emerging Trends
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. 5, S. 286 - 290
    ISSN: 2296-5262; 2296-5270
  • Cheung, Phyllis F.; Neff, Florian; Neander, Christian; Bazarna, Anna; Savvatakis, Konstantinos; Liffers, Sven-Thorsten; Althoff, Kristina; Lee, Chang-Lung; Moding, Everett J.; Kirsch, David G.; Saur, Dieter; Bazhin, Alexandr V.; Trajkovic-Arsic, Marija; Heikenwalder, Mathias F.; Siveke, Jens
    Notch-induced myeloid reprogramming in spontaneous pancreatic ductal adenocarcinoma by dual genetic targeting
    In: Cancer Research Jg. 78 (2018) Nr. 17, S. 4997 - 5010
    ISSN: 0008-5472; 1538-7445
  • Urban, Christian; Buck, Achim; Siveke, Jens; Lordick, Florian; Luber, Birgit; Walch, Axel; Aichler, Michaela
    PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI
    In: Biochimica et Biophysica Acta - General Subjects Jg. 1862 (2018) Nr. 1, S. 51 - 60
    ISSN: 0304-4165
  • Vogel, Arndt; Kasper, Stefan; Bitzer, Michael; Block, Andreas; Sinn, Marianne; Schulze-Bergkamen, Henning; Moehler, Markus; Pfarr, Nicole; Endris, Volker; Goeppert, Benjamin; Merx, Kirsten; Schnoy, Elisabeth; Siveke, Jens; Michl, Patrick; Waldschmidt, Dirk; Kuhlmann, Jan; Geissler, Michael; Kahl, Christoph; Evenkamp, Ralf; Schmidt, Torben; Kuhlmann, Alexander; Weichert, Wilko; Kubicka, Stefan
    PICCA study : panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer—a randomised biomarker-driven clinical phase II AIO study
    In: European Journal of Cancer Jg. 92 (2018) S. 11 - 19
    ISSN: 1879-2995; 0959-8049
  • Mercade, T. M.; Wang-Gillam, A.; Chen, L.; Blanc, J.; Lee, K.; Bodoky, G.; Dean, A.; Siveke, Jens; Mirakhur, B.; Chen, J.; de Jong, F.
    Prognostic effect of primary tumor location in the NAPOLI-1 phase 3 study in metastatic pancreatic ductal adenocarcinoma (mPDAC)
    In: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 5,
    ISSN: 0923-7534; 1569-8041
  • Lakatos, G.; Lee, K.; Siveke, Jens; Blanc, J.; Mercade, T. M.; Dean, A.; Bodoky, G.; Mirakhur, B.; Chen, J.; Wang-Gillam, A.; Chen, L.; de Jong, F.
    Prognostic value of baseline biliary stents on outcomes in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) in the NAPOLI-1 trial
    In: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 5, S. 42
    ISSN: 0923-7534; 1569-8041
  • Macarulla, T. M.; Hubner, R.; Blanc, J. F.; Wang-Gillam, A.; Li, C. P.; Bodoky, G.; Dean, A. P.; Yanshen, S.; Jameson, G. S.; Lee, K. H.; Chiu, C. F.; Schwartsmann, G.; Braiteh, F. S.; Cunningham, D.; Chen, L. T.; Von Hoff, D. D.; Mamlouk, K. K.; de Jong, F. A.; Siveke, Jens
    Subgroup analysis by baseline (BL) weight-associated parameters : A phase III study of liposomal irinotecan (nal-IRI)+/--5fluorouracil/leucovorin (5-FU/LV) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC) previously treated with g
    In: Journal of Clinical Oncology Jg. 36 (2018) Nr. Suppl. 4, S. 410
    ISSN: 0732-183X; 1527-7755
  • Macarulla, T. M.; Siveke, Jens; Dean, A. P.; Hubner, R.; Blanc, J. F.; Cunningham, D.; Chen, L. T.; Mirakhur, B.; Chen, J.; de Jong, F. A.; Wang-Gillam, A.
    Subgroup analysis by baseline pain intensity (BPI) and analgesic use (BAU) in NAPOLI-1 : A phase III study of liposomal irinotecan (nal IRI)+/- 5-fluorouracil/leucovorin (5-FU/LV) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC) p
    In: Journal of Clinical Oncology Jg. 36 (2018) Nr. Suppl. 4, S. 379
    ISSN: 0732-183X; 1527-7755
  • Siveke, Jens; Hubner, R.; Macarulla, T. M.; Wang-Gillam, A.; Dean, A. P.; Blanc, J. F.; Cunningham, D.; Mirakhur, B.; Belanger, B.; de Jong, F. A.; Chen, L. T.
    Subgroup analysis by measurable metastatic lesion (ML) number and selected lesion locations (LL) at baseline (BL) in NAPOLI-1 : A phase III study of liposomal irinotecan (nal-IRI)+/- 5-fluorouracil/leucovorin (5-FU/LV) in patients (pts) with metastatic pan
    In: Journal of Clinical Oncology Jg. 36 (2018) Nr. Suppl. 4, S. 460
    ISSN: 0732-183X; 1527-7755
  • Chen, Li-Tzong; Siveke, Jens; Wang-Gillam, Andrea; Li, Chung-Pin; Bodoky, György; Dean, Andrew P.; Shan, Yan-Shen; Jameson, Gayle S.; Macarulla, Teresa; Lee, Kyung-Hun; Cunningham, David; Blanc, Jean-Frédéric; Chiu, Chang-Fang; Schwartsmann, Gilberto; Braiteh, Fadi S.; Mamlouk, Khalid; Belanger, Bruce; de Jong, Floris A.; Hubner, Richard A.
    Survival with nal-IRI (liposomal irinotecan) plus 5-fluorouracil and leucovorin versus 5-fluorouracil and leucovorin in per-protocol and non-per-protocol populations of NAPOLI-1 : Expanded analysis of a global phase 3 trial
    In: European Journal of Cancer Jg. 105 (2018) S. 71 - 78
    ISSN: 0959-8049
  • Mercade, T. M.; Wang-Gillam, A.; Chen, L.; Blanc, J.; Lee, K.; Bodoky, G.; Dean, A.; Chen, J.; Mirakhur, B.; Siveke, Jens; de Jong, F.
    The effect of best response to prior anticancer therapy on efficacy outcomes in the NAPOLI-1 trial of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) previously treated with gemcitabine-based therapy
    In: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 5,
    ISSN: 0923-7534; 1569-8041
  • Trajkovic-Arsic, M.; Heid, I.; Steiger, K.; Gupta, A.; Fingerle, A.; Wörner, C.; Teichmann, N.; Sengkwawoh-Lueong, S.; Wenzel, P.; Beer, A.J.; Esposito, I.; Braren, R.; Siveke, Jens
    Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic ductal adenocarcinoma
    In: Scientific Reports Jg. 7 (2017)
    ISSN: 2045-2322
  • Frohling, S.; Barth, T. F.; Groschel, S.; Folprecht, G.; Richter, S.; Mayer-Steinacker, R.; Schultheiss, M.; Moller, P.; Bauer, S.; Siveke, Jens; Dettmer, S.; Richter, D.; Heining, C.; Horak, P.; Glimm, H.; Jager, D.; Von Kalle, C.; Schlenk, R.
    CDK4/6 inhibition in locally advanced/metastatic chordoma (NCT PMO-1601)
    In: Annals of Oncology Jg. 28 5 (2017)
    ISSN: 0923-7534; 1569-8041
  • Heid, Irina; Steiger, Katja; Trajkovic-Arsic, Marija; Settles, Marcus; Eßwein, Manuela R.; Erkan, Mert; Kleeff, Jörg; Jäger, Carsten; Friess, Helmut; Haller, Bernhard; Steingötter, Andreas; Schmid, Roland M.; Schwaiger, Markus; Rummeny, Ernst J.; Esposito, Irene; Siveke, Jens; Braren, Rickmer F.
    Co-clinical assessment of tumor cellularity in pancreatic cancer
    In: Clinical Cancer Research Jg. 23 (2017) Nr. 6, S. 1461 - 1470
    ISSN: 1557-3265; 1078-0432
  • Chen, Nai-Ming; Neesse, Albrecht; Dyck, Moritz Lino; Steuber, Benjamin; Koenig, Alexander O.; Lubeseder-Martellato, Clara; Winter, Thore; Forster, Teresa; Bohnenberger, Hanibal; Kitz, Julia; Reuter-Jessen, Kirsten; Griesmann, Heidi; Gaedcke, Jochen; Grade, Marian; Zhang, Jin-San; Tsai, Wan-Chi; Siveke, Jens; Schildhaus, Hans-Ulrich; Ströbel, Philipp; Johnsen, Steven A.; Ellenrieder, Volker; Hessmann, Elisabeth
    Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity
    In: Gastroenterology Jg. 152 (2017) Nr. 6, S. 1507 - 1520.e15
    ISSN: 1528-0012; 0016-5085
  • Hessmann, Elisabeth; Johnsen, Steven A; Siveke, Jens; Ellenrieder, Volker
    Epigenetic treatment of pancreatic cancer : Is there a therapeutic perspective on the horizon?
    In: Gut Jg. 66 (2017) Nr. 1, S. 168 - 179
    ISSN: 1468-3288; 0017-5749
  • Haas, Michael; Ormanns, Steffen; Baechmann, Sibylle; Remold, Anna; Kruger, Stephan; Westphalen, Christoph B.; Siveke, Jens; Wenzel, Patrick; Schlitter, Anna Melissa; Esposito, Irene; Quietzsch, Detlef; Clemens, Michael R.; Kettner, Erika; Laubender, Ruediger P.; Jung, Andreas; Kirchner, Thomas; Boeck, Stefan; Heinemann, Volker
    Extended RAS analysis and correlation with overall survival in advanced pancreatic cancer
    In: The British Journal of Cancer: BJC Jg. 116 (2017) Nr. 11, S. 1462 - 1469
    ISSN: 1532-1827; 0007-0920
  • Mishra, Vivek Kumar; Wegwitz, Florian; Kosinsky, Robyn Laura; Sen, Madhobi; Baumgartner, Roland; Wulff, Tanja; Siveke, Jens; Schildhaus, Hans-Ulrich; Najafova, Zeynab; Kari, Vijayalakshmi; Kohlhof, Hella; Hessmann, Elisabeth; Johnsen, Steven A.
    Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4-and MYC-dependent manner
    In: Nucleic Acids Research Jg. 45 (2017) Nr. 11, S. 6334 - 6349
    ISSN: 1362-4962; 0301-5610; 0305-1048
  • Schmohl, Kathrin A.; Gupta, Aayush; Grünwald, Geoffrey K.; Trajkovic-Arsic, Marija; Klutz, Kathrin; Braren, Rickmer; Schwaiger, Markus; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst; Siveke, Jens; Spitzweg, Christine
    Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
    In: OncoTarget Jg. 8 (2017) Nr. 20, S. 33393 - 33404
    ISSN: 1949-2553
  • Ma, Xiaopeng; Phi Van, Valerie; Kimm, Melanie A.; Prakash, Jaya; Kessler, Horst; Kosanke, Katja; Feuchtinger, Annette; Aichler, Michaela; Gupta, Aayush; Rummeny, Ernst J.; Eisenblätter, Michel; Siveke, Jens; Walch, Axel K.; Braren, Rickmer; Ntziachristos, Vasilis; Wildgruber, Moritz
    Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography for Imaging Tumor Progression and Early Response in Non-Small Cell Lung Cancer
    In: Neoplasia Jg. 19 (2017) Nr. 1, S. 8 - 16
    ISSN: 1476-5586; 1522-8002
  • Bäcker, Veronika; Cheung, Fung-Yi; Siveke, Jens; Fandrey, Joachim; Winning, Sandra
    Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis
    In: PLoS One Jg. 12 (2017) Nr. 12, S. e0190074
    ISSN: 1932-6203
  • Lubeseder-Martellato, Clara; Alexandrow, Katharina; Hidalgo-Sastre, Ana; Heid, Irina; Boos, Sophie Luise; Briel, Thomas; Schmid, Roland M.; Siveke, Jens
    Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions
    In: EBioMedicine Jg. 15 (2017) S. 90 - 99
    ISSN: 2352-3964
  • Hubner, R. A.; Chen, L. T.; Li, C. P.; Bodoky, G.; Dean, A.; Lee, K. H.; Cunningham, D.; Siveke, Jens; Braiteh, F. S.; de Jong, F. A.; Belanger, B.; Walls, R.; Mody, P. D.; von Hoff, D. D.; Wang-Gillam, A.
    Prognostic value of baseline neutrophil-to-lymphocyte ratio for predicting clinical outcome in metastatic pancreatic ductal adenocarcinoma (mPDAC) patients treated with liposomal irinotecan (nal-IRI)+5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV alon
    In: Ann Oncol Jg. 28 5 (2017)
    ISSN: 0923-7534; 1569-8041
  • Pelzer, Uwe; Blanc, Jean-Frédéric; Melisi, Davide; Cubillo, Antonio; Von Hoff, Daniel D.; Wang-Gillam, Andrea; Chen, Li-Tzong; Siveke, Jens; Wan, Yin; Solem, Caitlyn T.; Botteman, Marc F.; Yang, Yoojung; De Jong, Floris A.; Hubner, Richard A.
    Quality-adjusted survival with combination nal-IRIFU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy : a Q-TWiST analysis
    In: The British Journal of Cancer: BJC Jg. 116 (2017) Nr. 10, S. 1247 - 1253
    ISSN: 1532-1827; 0007-0920
  • Chen, L-T.; Dean, A.; Macarulla, T.; Belanger, B.; Cunningham, D.; Li, C-P.; Hubner, R.; Jameson, G.S.; Siveke, Jens; Wang-Gillam, A.; Lee, K-H.; von Hoff, D.D.; Bodoky, G.; Chiu, C-F.; Bayever, E.; Blanc, J-F.; Schwartsmann, G.; de Jong, F.; Shan, Y-S.; Braiteh, F.
    Final results of NAPOLI-1 : A phase 3 study of nal-IRI (MM-398) ± 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
    In: Annals of Oncology Jg. 27 (2016) Nr. Suppl. 6, S. 622PD
    ISSN: 1569-8041; 0923-7534
  • Heid, I.; Trajkovic-Arsic, M.; Steiger, K.; Settles, M.; Steingotter, A.; Gupta, A.; Lubeseder-Martellato, C.; Schmid, R. M.; Rummeny, E.; Siveke, Jens; Braren, R.
    Gemcitabine impairs tumor perfusion in stroma rich murine endogenous PDAC
    In: European Journal of Cancer Jg. 69 (2016) Nr. Suppl. 1, S. S67 - S68
    ISSN: 0959-8049
  • Hidalgo-Sastre, Ana; Brodylo, Roxanne L; Lubeseder-Martellato, Clara; Sipos, Bence; Steiger, Katja; Lee, Marcel; von Figura, Guido; Grünwald, Barbara; Zhong, Suyang; Trajkovic-Arsic, Marija; Neff, Florian; Schmid, Roland M; Siveke, Jens
    Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreatic Ductal Adenocarcinoma in a Mouse Model
    In: The American Journal of Pathology Jg. 186 (2016) Nr. 11, S. 2934 - 2944
    ISSN: 0002-9440; 1525-2191
  • Trajkovic-Arsic, M.; Kalideris, E.; Sun, N.; Feuchtinger, A.; Gupta, A.; Aichler, M.; Schmid, R. M.; Walch, A.; Siveke, Jens
    Identification of metabolic changes in Pancreatic Ductal Adenocarcinoma
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 76 - 77
    ISSN: 2296-5270
  • Diersch, S; Wirth, M; Schneeweis, C; Jörs, S; Geisler, F; Siveke, Jens; Rad, R; Schmid, R M; Saur, D; Rustgi, A K; Reichert, M; Schneider, G
    Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells
    In: Oncogene Jg. 35 (2016) Nr. 29, S. 3880 - 3886
    ISSN: 0950-9232; 1476-5594
  • Lubeseder-Martellato, Clara; Hidalgo-Sastre, Ana; Hartmann, Carolin; Alexandrow, Katharina; Kamyabi-Moghaddam, Zahra; Sipos, Bence; Wirth, Matthias; Neff, Florian; Reichert, Maximilian; Heid, Irina; Schneider, Günter; Braren, Rickmer; Schmid, Roland M; Siveke, Jens
    Membranous CD24 drives the epithelial phenotype of pancreatic cancer
    In: Oncotarget Jg. 7 (2016) Nr. 31, S. 49156 - 49168
    ISSN: 1949-2553
  • Grüner, Barbara M.; Winkelmann, Isabel; Feuchtinger, Annette; Sun, Na; Balluff, Benjamin; Teichmann, Nicole; Herner, Alexander; Kalideris, Evdokia; Steiger, Katja; Braren, Rickmer; Aichler, Michaela; Esposito, Irene; Schmid, Roland M.; Walch, Axel; Siveke, Jens
    Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancer
    In: Molecular Cancer Therapeutics Jg. 15 (2016) Nr. 5, S. 1145 - 1152
    ISSN: 1538-8514; 1535-7163
  • Braren, Rickmer F; Siveke, Jens
    Next-generation metabolic imaging in pancreatic cancer
    In: Gut Jg. 65 (2016) Nr. 3, S. 367 - 369
    ISSN: 0017-5749
  • Heid, I.; Lubeseder-Martellato, C.; Trajkovic-Arsic, M.; Rummeny, E.; Steiger, K.; Schmid, R. M.; Braren, R.; Siveke, Jens
    RAC1 activity is necessary for the development of murine undifferentiated PDAC
    In: Eur J Cancer Jg. 69 (2016) Nr. Suppl. 1, S. 140
    ISSN: 0959-8049
  • Bitzer, Michael; Horger, Marius; Giannini, Edoardo G; Ganten, Tom M; Wörns, Marcus A; Siveke, Jens; Dollinger, Matthias M; Gerken, Guido; Scheulen, Max Ernst; Wege, Henning; Zagonel, Vittorina; Cillo, Umberto; Trevisani, Franco; Santoro, Armando; Montesarchio, Vincenzo; Malek, Nisar P; Holzapfel, Julia; Herz, Thomas; Ammendola, Astrid S; Pegoraro, Stefano; Hauns, Bernhard; Mais, Anna; Lauer, Ulrich M; Henning, Stefan W; Hentsch, Bernd
    Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma - The SHELTER study
    In: Journal of Hepatology Jg. 65 (2016) Nr. 2, S. 280 - 288
    ISSN: 0168-8278
  • Wang-Gillam, A.; Belanger, B.; Jameson, G.S.; Li, C-P.; Mamlouk, K.; Cunningham, D.; Bodoky, G.; de Jong, F.; Hubner, R.A.; von Hoff, D.D.; Chiu, C-F.; Blanc, J-F.; Shan, Y-S.; Dean, A.; Lee, K-H.; Chen, L-T.; Schwartsmann, G.; Macarulla, T.; Braiteh, F.; Siveke, Jens
    Time course of selected treatment emergent adverse events (TEAEs) in NAPOLI-1 : A phase 3 study of nal-IRI (MM-398) ± 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
    In: Annals of Oncology Jg. 27 (2016) Nr. Suppl. 6, S. 693P
    ISSN: 1569-8041; 0923-7534
  • Dorneburg, Carmen; Goß, Annika V; Fischer, Matthias; Roels, Frederik; Barth, Thomas F E; Berthold, Frank; Kappler, Roland; Oswald, Franz; Siveke, Jens; Molenaar, Jan J; Debatin, Klaus-Michael; Beltinger, Christian
    γ-Secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets
    In: Oncotarget Jg. 7 (2016) Nr. 39, S. 62799 - 62813
    ISSN: 1949-2553
  • Ormanns, Steffen; Siveke, Jens; Heinemann, Volker; Haas, Michael L.; Sipos, Bence; Schlitter, Anna Melissa Elissa; Esposito, Iréne; Jung, Andreas; Laubender, Rüdiger Paul Aul; Kruger, Stephan; Vehling-Kaiser, Ursula; Winkelmann, Cornelia; Fischer von Weikersthal, Ludwig; Clemens, Michael Roland; Gauler, Thomas; Märten, Angela; Geissler, Michael; Greten, Tim F.; Kirchner, Thomas; Boeck, Stefan
    PERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer : a translational subgroup analysis from AIO-PK0104
    In: BMC Cancer Jg. 14 (2014) Nr. 1, S. 624
    ISSN: 1471-2407
  • Boeck, S. H.; Ormanns, S.; Laubender, R. P.; Jung, A.; Siveke, Jens; Haas, M.; Neumann, J.; Vehling-Kaiser, U.; Winkelmann, C.; von Weikersthal, L. F.; Clemens, M. R.; Gauler, Thomas; Marten, A.; Klein, S.; Kojouharoff, G.; Geissler, M.; Greten, T. F.; Kirchner, T.; Heinemann, V.
    Phosphorylated ERK (pERK) as biomarker in patients with advanced pancreatic cancer treated with erlotinib within a randomized phase III trial (AIO-PK0104)
    In: Journal of Clinical Oncology Jg. 31 (2013) Nr. 4 Suppl., S. 189
    ISSN: 0732-183X; 1527-7755
  • Bitzer, M.; Ganten, T. M.; Woerns, M. A.; Siveke, Jens; Dollinger, M. M.; Scheulen, Max Ernst; Wege, H.; Giannini, E. G.; Cillo, U.; Trevisani, F.; Santoro, A.; Montesarchio, V.; Mais, A.; Hauns, B.; Asche, J.; Herz, T.; Pegoraro, S.; Ammendola, A.; Henning, S. W.; Hentsch, B.; SHELTER Study Grp
    Resminostat in advanced hepatocellular carcinoma (HCC) : Overall survival subgroup analysis of prognostic factors in the SHELTER trial
    In: Journal of Clinical Oncology Jg. 31 (2013) Nr. 15 Suppl., S. e15088
    ISSN: 0732-183X; 1527-7755
  • Seufferlein, Thomas; Porzner, Marc; Becker, Thomas; Budach, Volker G.F.; Ceyhan, Güralp Onur; Esposito, Iréne; Fietkau, Rainer; Follmann, Markus; Friess, Helmut M.; Galle, Peter Robert; Geiler, M.; Glanemann, Matthias; Gress, Thomas Matthias; Heinemann, Volker; Hohenberger, Werner Max; Hopt, Ulrich Theodor; Izbicki, Jakob Robert; Klar, Ernst A.; Kleeff, J. H.; Kopp, Ina B.; Kullmann, Frank; Langer, T.; Langrehr, Jan Michael; Lerch, Markus M.; Löhr, Matthias J.; Lüttges, Jutta Elisabeth; Lutz, Manfred Paul; Mayerle, Julia V.; Michl, Patrick; Möller, Peter; Molls, Michael M.; Münter, Marc W.; Nothacker, Monika J.; Oettle, Helmut; Post, Stefan; Reinacher-Schick, Anke C.; Röcken, Christoph; Roeb, Elke; Saeger, Hans Detlev; Schmid, Roland Michael; Schmiegel, Wolff Helmut; Schoenberg, Michael H.; Siveke, Jens; Stuschke, Martin; Tannapfel, Andrea; Uhl, Waldemar H.; Unverzagt, Susanne; Van Oorschot, B.; Vashist, Yogesh Kumar; Werner, Jens; Yekebaş, Emre F.
    S3-Leitlinie zum exokrinen Pankreaskarzinom
    In: Zeitschrift für Gastroenterologie Jg. 51 (2013) Nr. 12, S. 1395 - 1440
    ISSN: 1439-7803
  • Bitzer, M.; Horger, M.; Ganten, T.; Ebert, M. P.; Siveke, Jens; Woerns, M. A.; Dollinger, M. M.; Gerken, Guido; Scheulen, Max Ernst; Mais, A.; Jankowsky, R.; Hauns, B.; Hentsch, B.; Lauer, U. M.
    Clinical update on the phase I/II trial of HDAC inhibitor resminostat in patients with sorafenib-resistant hepatocellular carcinoma (HCC) - The Shelter Study
    In: Annals of Oncology Jg. 22 (2011) Nr. Suppl. 5, S. v76 - v76
    ISSN: 0923-7534; 1569-8041
  • Abstracts

  • Kasper, Stefan; zur Hausen, Gerrit; Stein, Alexander; Stintzing, Sebastian; Berger, Andreas; Loges, Sonja; Hofheinz, Ralf; Trarbach, Tanja; Graeven, Ullrich; Fischer von Weikersthal, Ludwig; Goetze, Thorsten Oliver; Hagen, Volker A.; Burock, Susen; Hoffmeister, Albrecht; Dechow, Tobias Nicolaas; Pauligk, Claudia; Virchow, Isabel; Siveke, Jens; Al-Batran, Salah-Eddin; Schuler, Martin
    A phase IIb study of ramucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic, chemotherapy refractory colorectal cancer patients : The RAMTAS trial of the German AIO (KRK-0316)
    In: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15, S. TPS3617 - TPS3617
    ISSN: 0732-183X; 1527-7755
  • Horak, Peter; Heining, Christoph; Kreutzfeldt, Simon; Heilig, Christoph E.; Möhrmann, Lino; Gieldon, Laura; Fröhlich, Martina; Uhrig, Sebastian; Hübschmann, Daniel; Beck, Katja; Richter, Daniela; Wolf, Stephan; Pfütze, Katrin; Geörg, Christina; Meißburger, Bettina; Klauschen, Frederick; Ochsenreither, Sebastian; Folprecht, Gunnar; Siveke, Jens; Bauer, Sebastian; Kindler, Thomas; Brandts, Christian; Börries, Melanie; Bubnoff, Nikolas von; Spiekermann, Karsten; Jost, Philipp J.; Schulze-Osthoff, Klaus; Bitzer, Michael; Schirmacher, Peter; Kalle, Christof von; Schlenk, Richard; Klink, Barbara; Hutter, Barbara; Weichert, Wilko; Stenzinger, Albrecht; Schröck, Evelin; Brors, Benedikt; Glimm, Hanno; Fröhling, Stefan
    Clinical relevance of comprehensive genomic analysis in advanced-stage cancers and rare malignancies : Results from the MASTER trial of the German Cancer Consortium
    In: Cancer Research Jg. 79 (2019) Nr. Suppl. 13,
    ISSN: 1538-7445; 0008-5472
  • Lorenzen, Sylvie; Quante, Michael; Rauscher, Isabel; Slotta-Huspenina, Julia; Becker, Karl Friedrich; Weichert, Wilko; Feith, Marcus; Friess, Helmut; Combs, Stephanie E.; Weber, Wolfgang; Haller, Bernhard; Angele, Martin K.; Albertsmeier, Markus; Blankenstein, Christiane; Kasper, Stefan; Zimmermann, Jens Peter; Algül, Hana; Schmid, Roland M.; Schwaiger, Markus; Siveke, Jens
    PET-directed combined modality therapy for gastroesophageal junction cancer : First results of the prospective MEMORI trial
    In: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15, S. 4018 - 4018
    ISSN: 0732-183X; 1527-7755
  • Heid, I.; Steiger, K.; Trajkovic-Arsic, M.; Settles, M.; Eisswein, M.; Erkan, M.; Kleeff, J.; Jager, C.; Friess, H.; Haller, B.; Steingotter, A.; Schmid, R.; Schwaiger, M.; Rummeny, E.; Esposito, I.; Siveke, Jens; Braren, R.
    Co-clinical assessment of tumor cellularity in pancreatic cancer
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 175
    ISSN: 2296-5270
  • Siveke, Jens; Cubillo, A.; Blanc, J. F.; Melisi, D.; Von Hoff, D. D.; Wang-Gillam, A.; Chen, L. T.; Becker, C.; Mamlouk, K.; Belanger, B.; Yang, Y.; de Jong, F.; Hubner, R.
    Effects of nanoliposomal irinotecan (nal-IRI;MM-398) +/- 5-Fluorouracil and leucavorin (5-FU/LV) on quality of life (QoL) in NAPOLI-1 : a phase 3 study in patients (pts) with metastatic pancreatic adenocarcinoma (mPAC) previously treated with gemcitabine-b
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 259
    ISSN: 2296-5270
  • Siveke, Jens; Chen, L. T.; Von Hoff, D. D.; Li, C. P.; Wang-Gillam, A.; Bodoky, G.; Dean, A.; Shan, Y. S.; Jameson, G.; Macarulla, T.; Lee, K. H.; Cunningham, D.; Blanc, J. F.; Hubner, R. A.; Chiu, C. F.; Schwartsmann, G.; Braiteh, F.; Moyo, V.; Belanger, B.; Bayever, E.
    Expanded analyses of NAPOLI-1 : Phase 3 study of nal-IRI (MM-398), with or without 5-fluorouracil (5FU) and leucovorin (LV), versus 5-fluorouracil and leucovorin (5FU/LV), in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based the
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 170
    ISSN: 2296-5270
  • Kamyabi-Moghaddam, Z.; Wirth, M.; Babucke, M.; Blume, K.; Saur, D.; Schorn, S.; Martignoni, M. E.; Ceyhan, G.; Schmid, R. M.; Siveke, Jens; Schneider, G.; Reichert, M.
    Patient-derived organoids to model intra- and intertumoral heterogeneity of pancreatic cancer in high-throughput drug screens
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 162
    ISSN: 2296-5270
  • Pelzer, U.; Blanc, J. F.; Melisi, D.; Cubillo, A.; Von Hoff, D. D.; Wang-Gillam, A.; Chen, L. T.; Siveke, Jens; Wan, Y.; Solem, C. T.; Botteman, M.; Yang, Y.; de Jong, F.; Hubner, R.
    Quality-adjusted time without symptoms or toxicity (Q-TWIST) of nanoliposomal irinotecan (nal-IRI;MM-398) plus 5-fluorouracil and leucavorin (5-FU/LV) vs 5-FU/LV alone in patients with metastatic pancreatic adenocarcinoma (mPAC) previously treated with ge
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 260
    ISSN: 2296-5270
  • Neff, F.; Kirsch, D. G.; Saur, D.; Schmid, R. M.; Bazhin, A.; Heikenwalder, M. F.; Siveke, Jens
    Targeting notch for myeloid reprogramming in pancreatic cancer
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 16
    ISSN: 2296-5270
  • Trajkovic-Arsic, M.; Heid, I.; Steiger, K.; Gupta, A.; Fingerle, A.; Worner, C.; Teichmann, N.; Wenzel, P.; Herner, A.; Steingotter, A.; Beer, A.; Schweiger, M.; Settles, M.; Haller, B.; Esposito, I.; Rummeny, E.; Schmid, R. M.; Braren, R.; Siveke, Jens
    Use of Diffusion-weighted magnetic resonance imaging for therapy response evaluation in pancreatic cancer
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 113 - 114
    ISSN: 2296-5270
  • Moehler, M.; Thuss-Patience, P.; Schmoll, H. J.; Hegewisch-Becker, S.; Wilke, Hansjochen; Al-Batran, S. E.; Weissinger, F.; Kullmann, F.; von Weikerstahl, L. F.; Siveke, Jens; Kanzler, S.; Schimanski, C. C.; Otte, M.; Schollenberger, L.; Koenig, J.; Galle, P. R.;
    Na-Folfiri plus sunitinib versus Na-Folfiri alone in advanced chemorefractory esophagogastric cancer patients : A randomized double-blinded placebo-controlled multicentric AIO phase II trial
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,
    In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 74
    ISSN: 0378-584X; 1423-0240