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Prof. Dr. med. Jens Siveke

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • William, D.; Bermúdez, M.; Kübler, A.; Kahlert, C.; Distler, M.; Weitz, J.; Uhrig, S.; Fröhlich, M.; Hutter, B.; Aust, D.; Baretton, G.; Wimberger, P.; Kast, K.; Meisel, C.; Gieldon, L.; Porrmann, J.; Wagner, J.; Arlt, M.; Franke, M.; Fischer, J.; Hackmann, K.; Kreutzfeldt, S.; Mock, A.; Heilig, C.E.; Lipka, D.B.; Teleanu, M.-V.; Schlenk, R.F.; Brors, B.; Hübschmann, D.; Paramasivam, N.; Richter, D.; Beck, K.; Pfütze, K.; Buchhalter, I.; Weichert, W.; Herold, T.; Spiekermann, K.; Jost, P.J.; Keilholz, U.; Klauschen, F.; Bauer, Sebastian; Siveke, Jens; Kindler, T.; Boerries, M.; Illert, A.L.; Bitzer, M.; Schulze-Osthoff, K.; Schirmacher, P.; Stenzinger, A.; Horak, P.; Heining, C.; Folprecht, G.; Fröhling, S.; Glimm, H.; Schröck, E.; Jahn, A.
    17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome : a case for universal genetic testing?
    In: ESMO Gastrointestinal Oncology, Jg. 9, 2025, 100218
    DOI (Open Access)
  • Lanzafame, Helena; Heilig, Christoph E.; Wardelmann, Eva; Desaulniers, Mélanie; Pabst, Kim Magaly; Mavroeidi, Ilektra Antonia; Pretzell, Ina; Fragoso Costa, Pedro; Nader, Michael; Leyser, Stephan; Schuler, Martin; Bauer, Sebastian; Siveke, Jens Thomas; Kamkar, Leila; Kreutzfeldt, Simon; Fröhling, Stefan; Mühl, Sebastian; Herrmann, Ken; Fendler, Wolfgang Peter; Hamacher, Rainer
    90Y-FAPI-46 Theranostics Leads to Near-Complete Metabolic Response in 3 Patients with Solitary Fibrous Tumors
    In: Journal of Nuclear Medicine (JNM), Jg. 66, 2025, Nr. 9, S. 1378 – 1384
    DOI
  • Lahusen, Anton; Lutz, Manfred P.; Fang, Rui; Kirchner, Martina; Albus, Sarah; Kluck, Klaus; Karthaus, Meinolf; Schwarzer, Andreas; Siegler, Gabriele; Kleger, Alexander; Ettrich, Thomas J.; Becher, Alexander; Höfling, Sabine; Siveke, Jens T.; Budczies, Jan; Tannapfel, Andrea; Stenzinger, Albrecht; Cheung, Phyllis Fung-Yi; Eiseler, Tim; Seufferlein, Thomas
    An immune responsive tumor microenvironment imprints into PBMCs and predicts outcome in advanced pancreatic cancer : Lessons from the PREDICT trial
    In: Molecular Cancer, Jg. 24, 2025, Nr. 1, 202
    DOI (Open Access)
  • Wang, Guanwu; Liu, Dong; Al-Masri, Tarick M.; Otto, Carlos C.; Siveke, Jens; Lang, Sven A.; Ulmer, Tom F.; Olde-Damink, Steven; Luedde, Tom; Dahl, Edgar; Neumann, Ulf P.; Heij, Lara R.; Bednarsch, Jan
    Body Composition in Cholangiocarcinoma Affects Immune Cell Populations in the Tumor and Normal Liver Parenchyma
    In: Journal of Clinical and Experimental Hepatology, Jg. 15, 2025, Nr. 2, 102460
    DOI (Open Access)
  • Heid, Irina; Trajkovic-Arsic, Marija; Lohöfer, Fabian; Kaissis, Georgios; Harder, Felix N.; Mayer, Moritz; Topping, Geoffrey J.; Jungmann, Friderike; Crone, Barbara; Wildgruber, Moritz; Karst, Uwe; Liotta, Lucia; Algül, Hana; Yen, Hsi-Yu; Steiger, Katja; Weichert, Wilko; Siveke, Jens T.; Makowski, Marcus R.; Braren, Rickmer F.
    Correction to : Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine‑induced hypo‑vascularization
    In: European Journal of Nuclear Medicine and Molecular Imaging, Jg. 52, 2025, Nr. 10, S. 3916 – 3917
    DOI (Open Access)
  • Keyl, Julius; Keyl, Philipp; Montavon, Grégoire; Hosch, René; Brehmer, Alexander; Mochmann, Liliana; Jurmeister, Philipp; Dernbach, Gabriel; Kim, Moon; Koitka, Sven; Bauer, Sebastian; Bechrakis, Nikolaos; Forsting, Michael; Führer-Sakel, Dagmar; Glas, Martin; Grünwald, Viktor; Hadaschik, Boris; Haubold, Johannes; Herrmann, Ken; Kasper, Stefan; Kimmig, Rainer; Lang, Stephan; Rassaf, Tienush; Roesch, Alexander; Schadendorf, Dirk; Siveke, Jens T.; Stuschke, Martin; Sure, Ulrich; Totzeck, Matthias; Welt, Anja; Wiesweg, Marcel; Baba, Hideo A.; Nensa, Felix; Egger, Jan; Müller, Klaus-Robert; Schuler, Martin; Klauschen, Frederick; Kleesiek, Jens
    Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence
    In: Nature Cancer, Jg. 6, 2025, Nr. 2, S. 307 – 322
    DOI (Open Access)
  • Steinberg-Vorhoff, Hannah Luisa; Haubold, Johannes; Bauer, Sebastian; Richly, Heike; Siveke, Jens; Wimmer, Julia; Umutlu, Lale; Schaarschmidt, Benedikt; Theysohn, Jens M.; Ludwig, Johannes M.
    Degradable Starch Microsphere Transarterial Chemoembolization as Salvage Therapy in Patients with Uveal Melanoma Liver Metastases
    In: Journal of Vascular and Interventional Radiology (JVIR), Jg. 36, 2025, Nr. 9, S. 1418 – 1426.e1
    DOI (Open Access)
  • Storey, Claire M.; Altai, Mohamed; Lückerath, Katharina; Zedan, Wahed; Zhu, Henan; Breuer, Lara; Trajkovic-Arsic, Marija; Park, Julie; Hasson, Abbie; Siveke, Jens; Abou, Diane; Marks, Haley; Ulmert, Enna; Ridley, Alexander; Safi, Marcella; Lamminmäki, Urpo; Yuen, Constance; Geres, Susanne; Mao, Liqun; Cheng, Michael; Subudhi, Sumit K.; Siddiqui, Bilal A.; Federman, Noah; Czernin, Johannes; Herrmann, Ken; Bentolila, Laurent; Yang, Xia; Graeber, Thomas G.; Damoiseaux, Robert; Thorek, Daniel; Ulmert, David
    Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance
    In: Signal Transduction and Targeted Therapy, Jg. 10, 2025, Nr. 1, 319
    DOI (Open Access)
  • Steinberg-Vorhoff, Hannah Luisa; Drews, Marcel Alexander; Opitz, Marcel; Landeghem, Natalie Van; Salhöfer, Luca; Holtkamp, Mathias; Li, Yan; Haubold, Johannes; Siveke, Jens; Richly, Heike; Forsting, Michael; Schaarschmidt, Benedikt; Zensen, Sebastian; Van Landeghem, Natalie
    Does volume change of the spleen correlate with the therapy response in uveal melanoma patients with liver metastases undergoing hepatic artery infusion chemotherapy?
    In: Radiology and Oncology, Jg. 59, 2025, Nr. 3, S. 383 – 390
    DOI, Online Volltext (Open Access)
  • Barroux, Melissa; Househam, Jacob; Lakatos, Eszter; Ronel, Tahel; Baker, Ann-Marie; Salié, Henrike; Mossner, Maximilian; Smith, Kane; Kimberley, Chris; Nowinski, Salpie; Berner, Alison; Gunasri, Vinaya; Borgmann, Martin; Liffers, Sven; Jansen, Marnix; Caravagna, Giulio; Steiger, Katja; Slotta-Huspenina, Julia; Weichert, Wilko; Zapata, Luis; Giota, Eleftheria; Lorenzen, Sylvie; Alberstmeier, Markus; Chain, Benny; Friess, Helmut; Bengsch, Bertram; Schmid, Roland M.; Siveke, Jens T.; Quante, Michael; Graham, Trevor A.
    Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma
    In: Nature Cancer, Jg. 6, 2025, Nr. 5, S. 820 – 837
    DOI (Open Access)
  • Gallardo Zamora, L.; von Rundstedt, F.C.; Wach, C.; Fendler, Wolfgang; Maric, I.; Herrmann, Ken; Siveke, Jens; Cheung, P.F.-Y.; Grünwald, Viktor
    Fibroblast-directed PET imaging reveals a case of retroperitoneal fibrosis after immunotherapy for metastatic urothelial cancer of the upper tract
    In: Urology Case Reports, Jg. 61, 2025, 103105
    DOI (Open Access)
  • Höfer, Stefanie; Frasch, Larissa; Brajkovic, Sarah; Putzker, Kerstin; Lewis, Joe; Schürmann, Hendrik; Leone, Valentina; Sakhteman, Amirhossein; The, Matthew; Bayer, Florian P; Müller, Julian; Hamood, Firas; Siveke, Jens T.; Reichert, Maximilian; Kuster, Bernhard
    Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response
    In: Molecular Systems Biology, Jg. 21, 2025, Nr. 3, S. 231 – 253
    DOI (Open Access)
  • Tuz, Ali A.; Ghosh, Susmita; Karsch, Laura; Antler, Medina; Lakovic, Vivian; Lohmann, Sabrina; Lehmann, Amber Hope; Beer, Alexander; Nagel, Dennis; Jung, Marcel; Hörenbaum, Nils; Kaygusuz, Viola; Qefalia, Altea; Alshaar, Belal; Amookazemi, Niloufar; Bolsega, Silvia; Basic, Marijana; Siveke, Jens T.; Heiles, Sven; Grüneboom, Anika; Lueong, Smiths; Herz, Josephine; Sickmann, Albert; Hagemann, Nina; Hasenberg, Anja; Hermann, Dirk M.; Gunzer, Matthias; Singh, Vikramjeet
    Gut microbiota deficiency reduces neutrophil activation and is protective after ischemic stroke
    In: Journal of Neuroinflammation, Jg. 22, 2025, Nr. 1, 137
    DOI (Open Access)
  • Watanabe, Masao; Fendler, Wolfgang; Grafe, Hong; Hirmas, Nader; Hamacher, Rainer; Lanzafame, Helena; Pabst, Kim M.; Hautzel, Hubertus; Aigner, Clemens; Kasper, Stefan; von Tresckow, Bastian; Stuschke, Martin; Kümmel, Sherko; Lugnier, Celine; Hadaschik, Boris; Grünwald, Viktor; Zarrad, Fadi; Kersting, David; Siveke, Jens T.; Herrmann, Ken; Weber, Manuel
    Head-to-head comparison of ⁶⁸ Ga-FAPI-46 PET/CT, ¹⁸F-FDG PET/CT, and contrast-enhanced CT for the detection of various tumors
    In: Annals of Nuclear Medicine, Jg. 39, 2025, Nr. 3, S. 255 – 265
    DOI
  • Hosseini, Atefeh; Haj-Yehia, Elias; Korste, Sebastian; Kuzay, Yalcin; Trajkovic-Arsic, Marija; Settelmeier, Stephan; Cantore, Miriam; Ferenz, Katja; Siveke, Jens; Herrmann, Ken; Rassaf, Tienush; Hendgen-Cotta, Ulrike B.; Weber, Wolfgang A.; Varasteh, Zohreh
    How Rapidly Does the FAPI PET Signal Reverse Following Therapy? : Assessing the FAPI PET Signal in Hypertensive Cardiac Injury and Fibrosis in Mice
    In: Journal of Nuclear Medicine (JNM), Jg. 66, 2025, Nr. 11, S. 1757 – 1763
    DOI (Open Access)
  • Borys, Katarzyna; Haubold, Johannes; Keyl, Julius; Bali, Maria A.; De Angelis, Riccardo; Boni, Kévin Brou; Coquelet, Nicolas; Kohnke, Judith; Baldini, Giulia; Kroll, Lennard; Schramm, Sara; Stang, Andreas; Malamutmann, Eugen; Kleesiek, Jens; Kim, Moon; Kasper, Stefan; Siveke, Jens T.; Wiesweg, Marcel; Merkel-Jens, Anja; Schaarschmidt, Benedikt M.; Gruenwald, Viktor; Bauer, Sebastian; Oezcelik, Arzu; Bölükbas, Servet; Herrmann, Ken; Kimmig, Rainer; Lang, Stephan; Treckmann, Jürgen; Stuschke, Martin; Hadaschik, Boris; Umutlu, Lale; Forsting, Michael; Schadendorf, Dirk; Friedrich, Christoph M.; Schuler, Martin; Hosch, René; Nensa, Felix
    Leveraging Sarcopenia index by automated CT body composition analysis for pan cancer prognostic stratification
    In: npj Digital Medicine, Jg. 8, 2025, Nr. 1, 611
    DOI (Open Access)
  • Jo, Peter; Crede, Marie; Schild-Suhren, Stina; Friede, Tim; Pelzer, Uwe; Siveke, Jens; Ghadimi, Michael
    METAPANC – intensivierte Behandlung bei Patient*innen mit lokal operablem, aber oligometastasiertem Pankreaskarzinom : Multimodale chirurgische Therapie versus alleinige Chemotherapie – eine randomisierte, kontrollierte Phase-III-Studie (AIO-PAK-0219, IAG-VO-0822)
    In: Die Onkologie, Jg. 31, 2025, Nr. 10, S. 1015 – 1019
    DOI
  • Metzenmacher, Martin; Zaun, Gregor; Trajkovic-Arsic, Marija; Cheung, Phyllis; Reissig, Timm M.; Schürmann, Hendrik; von Neuhoff, Nils; O'Kane, Grainne; Ramotar, Stephanie; Dodd, Anna; Gallinger, Steven; Muckenhuber, Alexander; Knox, Jennifer J.; Kunzmann, Volker; Horn, Peter; Hoheisel, Jörg D.; Siveke, Jens T.; Lueong, Smiths S.
    Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell-free RNA
    In: Molecular Oncology, Jg. 19, 2025, Nr. 2, S. 357 – 376
    DOI, Online Volltext (Open Access)
  • Zhao, Ben; Fang, Rui; Schürmann, Hendrik; Hemmer, Erik Jan; Mayer, Gina Lauren; Trajkovic-Arsic, Marija; Althoff, Kristina; Yang, Jiajin; Godfrey, Laura; Liffers, Sven T.; Savvatakis, Konstantinos; Dorsch, Madeleine; Grüner, Barbara M.; Hahn, Stephan; Remke, Marc; Lueong, Smiths S.; Siveke, Jens T.
    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
    In: Cell Reports, Jg. 44, 2025, Nr. 4, 115541
    DOI (Open Access)
  • Ghadimi, Michael; Pelzer, Uwe; Besselink, Marc G.; Siveke, Jens; Telgmann, Ralph; Braren, Rickmer; Wilmink, Hanneke; Crede, Marie; Koenig, Alexander; Koenig, Ute; Liffers, Sven Thorsten; Antweiler, Kai; Uijterwijk, Bas; Seppanen, Hanna; Nordin, Arno; Puolakkainen, Pauli; Dajani, Olav F.; Labori, Knut Jørgen; Johansson, Mia; Bratlie, Svein Olav; Friede, Tim; Jo, Peter
    Study protocol of the METAPANC trial - intensified treatment in patients with local operable but oligometastatic pancreatic cancer - multimodal surgical treatment versus chemotherapy alone : A randomized controlled trial
    In: BMC Cancer, Jg. 25, 2025, Nr. 1, 208
    DOI (Open Access)
  • Wang, Guanwu; Mantas, Anna; Liu, Dong; Al-Masri, Tarick M.; Lueong, Smiths Sengkwawoh; Siveke, Jens; Luedde, Tom; Ulmer, Tom F.; Amygdalos, Iakovos; Vondran, Florian W. R.; Lurje, Georg; Neumann, Ulf Peter; Heij, Lara R.; Bednarsch, Jan
    The Prognostic Value of the XPC rs2228001 Single Nucleotide Polymorphism in Cholangiocarcinoma
    In: Liver International, Jg. 45, 2025, Nr. 9, e70292
    DOI (Open Access)
  • Rao, Shalini V.; Young, Lisa; Cheeseman, Danya; Flynn, Sean; Krebs, Niklas; Couturier, Dominique-Laurent; Mack, Stephanie; Brais, Rebecca; Temple, Jill; Smith, Amy; Papachristou, Evangelia; Pelicano, Catarina; Chilamakuri, Chandra Sekhar Reddy; Herka, Krzysztof; Baba, Hideo Andreas; Farah, Luay; Cheung, Phyllis F.; Siveke, Jens; Guerrier, Stéphane; Insolia, Luca; Gill, Michael; Archer Goode, Emily; Kupczak, Steven; Cheng, Yi; Borsari, Giacomo; Jodrell, Duncan; D’Santos, Clive; Russell, Alasdair; Grünwald, Barbara; Serrao, Eva; Chernukhin, Igor; Carroll, Jason S.
    Transcription factor switching drives subtype-specific pancreatic cancer
    In: Nature Genetics, Jg. 57, 2025, Nr. 12, S. 3016 – 3026
    DOI (Open Access)
  • Pabst, Kim M; Weber, Manuel; Laschinsky, Christina; Sandach, Patrick; Bartel, Timo; Küper, Alina T; Kessler, Lukas; Trajkovic-Arsic, Marija; Eckstein, Markus; Gilman, Elena; Nader, Michael; Barbato, Francesco; Podleska, Lars; Hadaschik, Boris; Hamacher, Rainer; Kersting, David; von Ostau (N.), Nicola; von Tresckow, Bastian; Kaelberlah, Hans-Peter; Kesch, Claudia; Kuemmel, Sherko; Reinacher-Schick, Anke; Schuler, Martin; Siveke, Jens; Grünwald, Viktor; Herrmann, Ken; Fendler, Wolfgang P.
    [⁶⁸Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation : A single-centre, single-arm, interventional, phase 2 trial
    In: The Lancet Oncology, Jg. 26, 2025, Nr. 9, S. 1204 – 1214
    DOI (Open Access)
  • Lanzafame, Helena; Mavroeidi, Ilektra A.; Pabst, Kim M.; Desaulniers, Mélanie; Ingenwerth, Marc; Hirmas, Nader; Kessler, Lukas; Nader, Michael; Bartel, Timo; Leyser, Stephan; Barbato, Francesco; Schuler, Martin; Bauer, Sebastian; Siveke, Jens T.; Herrmann, Ken; Hamacher, Rainer; Fendler, Wolfgang P.
    68Ga-Fibroblast Activation Protein Inhibitor PET/CT Improves Detection of Intermediate and Low-Grade Sarcomas and Identifies Candidates for Radiopharmaceutical Therapy
    In: Journal of Nuclear Medicine (JNM), Jg. 65, 2024, Nr. 6, S. 880 – 887
    DOI
  • Steinberg-Vorhoff, Hannah L; Ting, Saskia C; Zensen, Sebastian; Ludwig, Johannes M; Li, Yan; Richly, Heike; Grüneisen, Johannes; Siveke, Jens T.; Theysohn, Jens; Schaarschmidt, Benedikt
    Are histomorphological patterns a predictor for survival in uveal melanoma patients with hepatic metastases undergoing hepatic artery infusion chemotherapy?
    In: Journal of Medical Imaging and Radiation Oncology, Jg. 68, 2024, Nr. 7, S. 862 – 869
    DOI (Open Access)
  • Lu, I-Na; Cheung, Phyllis Fung-Yi; Heming, Michael; Thomas, Christian; Giglio, Giovanni; Leo, Markus; Erdemir, Merve; Wirth, Timo; König, Simone; Dambietz, Christine A.; Schroeter, Christina B.; Nelke, Christopher; Siveke, Jens T.; Ruck, Tobias; Klotz, Luisa; Haider, Carmen; Höftberger, Romana; Kleinschnitz, Christoph; Wiendl, Heinz; Hagenacker, Tim; Meyer zu Horste, Gerd
    Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment
    In: Nature Communications, Jg. 15, 2024, Nr. 1, 4120
    DOI (Open Access)
  • Hörst, Fabian; Rempe, Moritz; Heine, Lukas; Seibold, Constantin; Keyl, Julius; Baldini, Giulia; Ugurel, Selma; Siveke, Jens; Grünwald, Barbara; Egger, Jan; Kleesiek, Jens
    CellViT : Vision Transformers for precise cell segmentation and classification
    In: Medical Image Analysis, Jg. 94, 2024, 103143
    DOI (Open Access)
  • Weiss, L.; Fischer, L.E.; Heinemann, V.; Gieseler, F.; Hoehler, T.; Mayerle, J.; Quietzsch, D.; Reinacher-Schick, A.; Schenk, M.; Seipelt, G.; Siveke, Jens T.; Stahl, Michael; Kaiser, U.; Waldschmidt, D.T.; Dorman, K.; Zhang, D.; Westphalen, C.B.; Boeck, S.; Haas, M.
    Changes over time in the course of advanced pancreatic cancer treatment with systemic chemotherapy : a pooled analysis of five clinical trials from two decades of the German AIO study group
    In: ESMO Open, Jg. 9, 2024, Nr. 4, 102944
    DOI (Open Access)
  • Hartlapp, I.; Valta-Seufzer, D.; Siveke, Jens T.; Algül, H.; Goekkurt, E.; Siegler, G.; Martens, U.M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T.J.; Held, S.; Keller, R.; Anger, F.; Germer, C.T.; Stang, A.; Kimmel, B.; Heinemann, V.; Kunzmann, V.
    Corrigendum to “Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: (NEOLAP-AIO-PAK-0113)” : results from a prospective, multicenter phase II trial
    In: ESMO Open, Jg. 9, 2024, Nr. 5, 103463
    DOI (Open Access)
  • Bauer, Nicolas; Balourdas, Dimitrios-Ilias; Schneider, Joel R.; Zhang, Xin; Berger, Lena M.; Berger, Benedict-Tilman; Schwalm, Martin P.; Klopp, Nick A.; Siveke, Jens T.; Knapp, Stefan; Joerger, Andreas C.
    Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization
    In: ACS Chemical Biology, Jg. 19, 2024, Nr. 2, S. 266 – 279
    DOI, Online Volltext (Open Access)
  • Hirmas, Nader; Hamacher, Rainer; Sraieb, Miriam; Kessler, Lukas; Pabst, Kim M.; Barbato, Francesco; Lanzafame, Helena; Kasper, Stefan; Nader, Michael; Kesch, Claudia; von Tresckow, Bastian; Hautzel, Hubertus; Aigner, Clemens; Glas, Martin; Stuschke, Martin; Kümmel, Sherko; Harter, Philipp; Lugnier, Celine; Uhl, Waldemar; Hadaschik, Boris; Grünwald, Viktor; Siveke, Jens T.; Herrmann, Ken; Fendler, Wolfgang
    Diagnostic Accuracy of ⁶⁸Ga-FAPI Versus ¹⁸F-FDG PET in Patients with Various Malignancies
    In: Journal of Nuclear Medicine (JNM), Jg. 65, 2024, Nr. 3, S. 372 – 378
    DOI (Open Access)
  • Veghini, Lisa; Pasini, Davide; Fang, Rui; Delfino, Pietro; Filippini, Dea; Neander, Christian; Vicentini, Caterina; Fiorini, Elena; Lupo, Francesca; D'Agosto, Sabrina L.; Carbone, Carmine; Agostini, Antonio; Piro, Geny; Rosa, Diego; Bevere, Michele; Markus, Peter; Behrens, Diana; Luchini, Claudio; Lawlor, Rita T.; Scarpa, Aldo; Biffi, Giulia; Cheung, Phyllis F.; Siveke, Jens T.; Corbo, Vincenzo
    Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer
    In: Nature Communications, Jg. 15, 2024, Nr. 1, 10534
    DOI (Open Access)
  • Hamacher, Rainer; Pabst, Kim M.; Cheung, Phyllis F.; Heilig, Christoph E.; Hüllein, Jennifer; Liffers, Sven-Thorsten; Borchert, Sabrina; Fragoso Costa, Pedro; Schaarschmidt, Benedikt; Kessler, Lukas; Miera, Monika A.; Droste, Margret; Akbulut, Merve; Falkenhorst, Johanna; Zarrad, Fadi; Kostbade, Karina; Mavroeidi, Ilektra A.; Glimm, Hanno; Umutlu, Lale; Schuler, Martin; Hübschmann, Daniel; Bauer, Sebastian; Fröhling, Stefan; Herrmann, Ken; Siveke, Jens T.; Schildhaus, Hans-Ulrich; Fendler, Wolfgang P.
    Fibroblast Activation Protein α-Directed Imaging and Therapy of Solitary Fibrous Tumor
    In: Journal of Nuclear Medicine (JNM), Jg. 65, 2024, Nr. 2, S. 252 – 257
    DOI (Open Access)
  • Kessler, Lukas; Schwaning, Felix; Metzenmacher, Martin; Pabst, Kim; Siveke, Jens; Trajkovic-Arsic, Marija; Schaarschmidt, Benedikt; Wiesweg, Marcel; Aigner, Clemens; Plönes, Till; Darwiche, Kaid; Bölükbas, Servet; Stuschke, Martin; Umutlu, Lale; Nader, Michael; Theegarten, Dirk; Hamacher, Rainer; Eberhardt, Wilfried; Schuler, Martin; Herrmann, Ken; Fendler, Wolfgang P.; Hautzel, Hubertus
    Fibroblast Activation Protein-Directed Imaging Outperforms ¹⁸F-FDG PET/CT in Malignant Mesothelioma : A Prospective, Single-Center, Observational Trial
    In: Journal of Nuclear Medicine (JNM), Jg. 65, 2024, Nr. 8, S. 1188 – 1193
    DOI
  • Smeets, Esther M M; Trajkovic-Arsic, Marija; Geijs, Daan; Karakaya, Sinan; van Zanten, Monica; Brosens, Lodewijk A A; Feuerecker, Benedikt; Gotthardt, Martin; Siveke, Jens T.; Braren, Rickmer; Ciompi, Francesco; Aarntzen, Erik H J G
    Histology-Based Radiomics for [¹⁸F]FDG PET Identifies Tissue Heterogeneity in Pancreatic Cancer
    In: Journal of Nuclear Medicine (JNM), Jg. 65, 2024, Nr. 7, S. 1151 – 1159
    DOI (Open Access)
  • Stang, Andreas; Wellmann, Ina; Holleczek, Bernd; Kim-Wanner, Soo-Zin; Müller-Nordhorn, Jacqueline; Sirri, Eunice; Wittenberg, Ian; Siveke, Jens T.; Kajüter, Hiltraud
    Incidence and survival of patients with malignant pancreatic neuroendocrine neoplasms in Germany, 2009–2021
    In: Cancer Epidemiology, Jg. 93, 2024, 102659
    DOI (Open Access)
  • Zensen, Sebastian; Steinberg-Vorhoff, Hannah L; Milosevic, Aleksandar; Richly, Heike; Siveke, Jens T.; Opitz, Marcel; Haubold, Johannes; Li, Yan; Forsting, Michael; Schaarschmidt, Benedikt
    Liver volumetry improves evaluation of treatment response to hepatic artery infusion chemotherapy in uveal melanoma patients with liver metastases
    In: Radiology and Oncology, Jg. 58, 2024, Nr. 4, S. 509 – 516
    DOI, Online Volltext (Open Access)
  • De Lazzari, Nico; Götte, Miriam; Kasper, Stefan; Meier, Eileen; Schuler, Martin; Pogorzelski, Michael; Siveke, Jens T.; Tewes, Mitra
    P-move : A randomized control trial of exercise in patients with advanced pancreatic or biliary tract cancer (aPBC) receiving beyond first-line chemotherapy
    In: Supportive Care in Cancer, Jg. 32, 2024, Nr. 7, 437
    DOI (Open Access)
  • Godfrey, Laura K.; Forster, Jan; Liffers, Sven-Thorsten; Schröder, Christopher; Köster, Johannes; Henschel, Leonie; Ludwig, Kerstin U.; Lähnemann, David; Trajkovic-Arsic, Marija; Behrens, Diana; Scarpa, Aldo; Lawlor, Rita T.; Witzke, Kathrin E.; Sitek, Barbara; Johnsen, Steven A.; Rahmann, Sven; Horsthemke, Bernhard; Zeschnigk, Michael; Siveke, Jens T.
    Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation
    In: Clinical Epigenetics, Jg. 16, 2024, Nr. 1, 13
    DOI, Online Volltext (Open Access)
  • Watanabe, Masao; Fendler, Wolfgang; Grafe, Hong; Hirmas, Nader; Hamacher, Rainer; Lanzafame, Helena; Pabst, Kim M.; Hautzel, Hubertus; Aigner, Clemens; Kasper, Stefan; von Tresckow, Bastian; Stuschke, Martin; Kümmel, Sherko; Lugnier, Celine; Hadaschik, Boris; Grünwald, Viktor; Zarrad, Fadi; Siveke, Jens T.; Herrmann, Ken; Weber, Manuel
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  • Urban, Christian; Buck, Achim; Siveke, Jens T.; Lordick, Florian; Luber, Birgit; Walch, Axel; Aichler, Michaela
    PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI
    In: Biochimica et Biophysica Acta (BBA) - General Subjects, Jg. 1862, 2018, Nr. 1, S. 51 – 60
    DOI, Online Volltext (Open Access)
  • Vogel, Arndt; Kasper, Stefan; Bitzer, Michael; Block, Andreas; Sinn, Marianne; Schulze-Bergkamen, Henning; Moehler, Markus; Pfarr, Nicole; Endris, Volker; Goeppert, Benjamin; Merx, Kirsten; Schnoy, Elisabeth; Siveke, Jens T.; Michl, Patrick; Waldschmidt, Dirk; Kuhlmann, Jan; Geissler, Michael; Kahl, Christoph; Evenkamp, Ralf; Schmidt, Torben; Kuhlmann, Alexander; Weichert, Wilko; Kubicka, Stefan
    PICCA study : panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer ; a randomised biomarker-driven clinical phase II AIO study
    In: European Journal of Cancer (EJC), Jg. 92, 2018, S. 11 – 19
    DOI
  • Chen, Li-Tzong; Siveke, Jens T.; Wang-Gillam, Andrea; Li, Chung-Pin; Bodoky, György; Dean, Andrew P.; Shan, Yan-Shen; Jameson, Gayle S.; Macarulla, Teresa; Lee, Kyung-Hun; Cunningham, David; Blanc, Jean-Frédéric; Chiu, Chang-Fang; Schwartsmann, Gilberto; Braiteh, Fadi S.; Mamlouk, Khalid; Belanger, Bruce; de Jong, Floris A.; Hubner, Richard A.
    Survival with nal-IRI (liposomal irinotecan) plus 5-fluorouracil and leucovorin versus 5-fluorouracil and leucovorin in per-protocol and non-per-protocol populations of NAPOLI-1 : Expanded analysis of a global phase 3 trial
    In: European Journal of Cancer (EJC), Jg. 105, 2018, S. 71 – 78
    DOI (Open Access)
  • Trajkovic-Arsic, M.; Heid, I.; Steiger, K.; Gupta, A.; Fingerle, A.; Wörner, C.; Teichmann, N.; Sengkwawoh-Lueong, S.; Wenzel, P.; Beer, A.J.; Esposito, I.; Braren, R.; Siveke, Jens T.
    Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic ductal adenocarcinoma
    In: Scientific Reports, Jg. 7, 2017, 17038
    DOI (Open Access)
  • Heid, Irina; Steiger, Katja; Trajkovic-Arsic, Marija; Settles, Marcus; Eßwein, Manuela R.; Erkan, Mert; Kleeff, Jörg; Jäger, Carsten; Friess, Helmut; Haller, Bernhard; Steingötter, Andreas; Schmid, Roland M.; Schwaiger, Markus; Rummeny, Ernst J.; Esposito, Irene; Siveke, Jens T.; Braren, Rickmer F.
    Co-clinical assessment of tumor cellularity in pancreatic cancer
    In: Clinical Cancer Research, Jg. 23, 2017, Nr. 6, S. 1461 – 1470
    DOI
  • Chen, Nai-Ming; Neesse, Albrecht; Dyck, Moritz Lino; Steuber, Benjamin; Koenig, Alexander O.; Lubeseder-Martellato, Clara; Winter, Thore; Forster, Teresa; Bohnenberger, Hanibal; Kitz, Julia; Reuter-Jessen, Kirsten; Griesmann, Heidi; Gaedcke, Jochen; Grade, Marian; Zhang, Jin-San; Tsai, Wan-Chi; Siveke, Jens; Schildhaus, Hans-Ulrich; Ströbel, Philipp; Johnsen, Steven A.; Ellenrieder, Volker; Hessmann, Elisabeth
    Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity
    In: Gastroenterology, Jg. 152, 2017, Nr. 6, S. 1507 – 1520.e15
    DOI (Open Access)
  • Hessmann, Elisabeth; Johnsen, Steven A; Siveke, Jens T.; Ellenrieder, Volker
    Epigenetic treatment of pancreatic cancer : Is there a therapeutic perspective on the horizon?
    In: Gut, Jg. 66, 2017, Nr. 1, S. 168 – 179
    DOI (Open Access)
  • Haas, Michael; Ormanns, Steffen; Baechmann, Sibylle; Remold, Anna; Kruger, Stephan; Westphalen, Christoph B.; Siveke, Jens T.; Wenzel, Patrick; Schlitter, Anna Melissa; Esposito, Irene; Quietzsch, Detlef; Clemens, Michael R.; Kettner, Erika; Laubender, Ruediger P.; Jung, Andreas; Kirchner, Thomas; Boeck, Stefan; Heinemann, Volker
    Extended RAS analysis and correlation with overall survival in advanced pancreatic cancer
    In: British Journal of Cancer (BJC), Jg. 116, 2017, Nr. 11, S. 1462 – 1469
    DOI (Open Access)
  • Mishra, Vivek Kumar; Wegwitz, Florian; Kosinsky, Robyn Laura; Sen, Madhobi; Baumgartner, Roland; Wulff, Tanja; Siveke, Jens T.; Schildhaus, Hans-Ulrich; Najafova, Zeynab; Kari, Vijayalakshmi; Kohlhof, Hella; Hessmann, Elisabeth; Johnsen, Steven A.
    Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4-and MYC-dependent manner
    In: Nucleic Acids Research, Jg. 45, 2017, Nr. 11, S. 6334 – 6349
    DOI (Open Access)
  • Schmohl, Kathrin A.; Gupta, Aayush; Grünwald, Geoffrey K.; Trajkovic-Arsic, Marija; Klutz, Kathrin; Braren, Rickmer; Schwaiger, Markus; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst; Siveke, Jens T.; Spitzweg, Christine
    Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
    In: OncoTarget, Jg. 8, 2017, Nr. 20, S. 33393 – 33404
    DOI (Open Access)
  • Ma, Xiaopeng; Phi Van, Valerie; Kimm, Melanie A.; Prakash, Jaya; Kessler, Horst; Kosanke, Katja; Feuchtinger, Annette; Aichler, Michaela; Gupta, Aayush; Rummeny, Ernst J.; Eisenblätter, Michel; Siveke, Jens; Walch, Axel K.; Braren, Rickmer; Ntziachristos, Vasilis; Wildgruber, Moritz
    Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography for Imaging Tumor Progression and Early Response in Non-Small Cell Lung Cancer
    In: Neoplasia: An International Journal for Oncology Research, Jg. 19, 2017, Nr. 1, S. 8 – 16
    DOI, Online Volltext (Open Access)
  • Bäcker, Veronika; Cheung, Fung-Yi; Siveke, Jens T.; Fandrey, Joachim; Winning, Sandra
    Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis
    In: PLoS ONE, Jg. 12, 2017, Nr. 12, e0190074
    DOI (Open Access)
  • Lubeseder-Martellato, Clara; Alexandrow, Katharina; Hidalgo-Sastre, Ana; Heid, Irina; Boos, Sophie Luise; Briel, Thomas; Schmid, Roland M.; Siveke, Jens T.
    Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions
    In: eBioMedicine, Jg. 15, 2017, S. 90 – 99
    DOI, Online Volltext (Open Access)
  • Pelzer, Uwe; Blanc, Jean-Frédéric; Melisi, Davide; Cubillo, Antonio; Von Hoff, Daniel D.; Wang-Gillam, Andrea; Chen, Li-Tzong; Siveke, Jens T.; Wan, Yin; Solem, Caitlyn T.; Botteman, Marc F.; Yang, Yoojung; De Jong, Floris A.; Hubner, Richard A.
    Quality-adjusted survival with combination nal-IRIFU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy : a Q-TWiST analysis
    In: British Journal of Cancer (BJC), Jg. 116, 2017, Nr. 10, S. 1247 – 1253
    DOI (Open Access)
  • Hidalgo-Sastre, Ana; Brodylo, Roxanne L; Lubeseder-Martellato, Clara; Sipos, Bence; Steiger, Katja; Lee, Marcel; von Figura, Guido; Grünwald, Barbara; Zhong, Suyang; Trajkovic-Arsic, Marija; Neff, Florian; Schmid, Roland M; Siveke, Jens T.
    Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreatic Ductal Adenocarcinoma in a Mouse Model
    In: The American Journal of Pathology, Jg. 186, 2016, Nr. 11, S. 2934 – 2944
    DOI
  • Diersch, S; Wirth, M; Schneeweis, C; Jörs, S; Geisler, F; Siveke, Jens T.; Rad, R; Schmid, R M; Saur, D; Rustgi, A K; Reichert, M; Schneider, G
    Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells
    In: Oncogene, Jg. 35, 2016, Nr. 29, S. 3880 – 3886
    DOI, Online Volltext (Open Access)
  • Lubeseder-Martellato, Clara; Hidalgo-Sastre, Ana; Hartmann, Carolin; Alexandrow, Katharina; Kamyabi-Moghaddam, Zahra; Sipos, Bence; Wirth, Matthias; Neff, Florian; Reichert, Maximilian; Heid, Irina; Schneider, Günter; Braren, Rickmer; Schmid, Roland M; Siveke, Jens T.
    Membranous CD24 drives the epithelial phenotype of pancreatic cancer
    In: OncoTarget, Jg. 7, 2016, Nr. 31, S. 49156 – 49168
    DOI (Open Access)
  • Grüner, Barbara M.; Winkelmann, Isabel; Feuchtinger, Annette; Sun, Na; Balluff, Benjamin; Teichmann, Nicole; Herner, Alexander; Kalideris, Evdokia; Steiger, Katja; Braren, Rickmer; Aichler, Michaela; Esposito, Irene; Schmid, Roland M.; Walch, Axel; Siveke, Jens T.
    Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancer
    In: Molecular Cancer Therapeutics, Jg. 15, 2016, Nr. 5, S. 1145 – 1152
    DOI (Open Access)
  • Braren, Rickmer F; Siveke, Jens T.
    Next-generation metabolic imaging in pancreatic cancer
    In: Gut, Jg. 65, 2016, Nr. 3, S. 367 – 369
    DOI
  • Bitzer, Michael; Horger, Marius; Giannini, Edoardo G; Ganten, Tom M; Wörns, Marcus A; Siveke, Jens T.; Dollinger, Matthias M; Gerken, Guido; Scheulen, Max Ernst; Wege, Henning; Zagonel, Vittorina; Cillo, Umberto; Trevisani, Franco; Santoro, Armando; Montesarchio, Vincenzo; Malek, Nisar P; Holzapfel, Julia; Herz, Thomas; Ammendola, Astrid S; Pegoraro, Stefano; Hauns, Bernhard; Mais, Anna; Lauer, Ulrich M; Henning, Stefan W; Hentsch, Bernd
    Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma - The SHELTER study
    In: Journal of Hepatology, Jg. 65, 2016, Nr. 2, S. 280 – 288
    DOI
  • Dorneburg, Carmen; Goß, Annika V; Fischer, Matthias; Roels, Frederik; Barth, Thomas F E; Berthold, Frank; Kappler, Roland; Oswald, Franz; Siveke, Jens T.; Molenaar, Jan J; Debatin, Klaus-Michael; Beltinger, Christian
    γ-Secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets
    In: OncoTarget, Jg. 7, 2016, Nr. 39, S. 62799 – 62813
    DOI (Open Access)
  • Ormanns, Steffen; Siveke, Jens T.; Heinemann, Volker; Haas, Michael L.; Sipos, Bence; Schlitter, Anna Melissa Elissa; Esposito, Iréne; Jung, Andreas; Laubender, Rüdiger Paul Aul; Kruger, Stephan; Vehling-Kaiser, Ursula; Winkelmann, Cornelia; Fischer von Weikersthal, Ludwig; Clemens, Michael Roland; Gauler, Thomas; Märten, Angela; Geissler, Michael; Greten, Tim F.; Kirchner, Thomas; Boeck, Stefan
    PERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer : a translational subgroup analysis from AIO-PK0104
    In: BMC Cancer, Jg. 14, 2014, Nr. 1, 624
    DOI (Open Access)
  • Boeck, S. H.; Ormanns, S.; Laubender, R. P.; Jung, A.; Siveke, Jens T.; Haas, M.; Neumann, J.; Vehling-Kaiser, U.; Winkelmann, C.; von Weikersthal, L. F.; Clemens, M. R.; Gauler, Thomas C.; Marten, A.; Klein, S.; Kojouharoff, G.; Geissler, M.; Greten, T. F.; Kirchner, T.; Heinemann, V.
    Phosphorylated ERK (pERK) as biomarker in patients with advanced pancreatic cancer treated with erlotinib within a randomized phase III trial (AIO-PK0104)
    2013 Gastrointestinal Cancers Symposium, January 24-26, 2013, San Francisco, CA, USA,
    In: Journal of Clinical Oncology (JCO), Jg. 31, 2013, Nr. 4 Suppl., S. 189
    DOI
  • Seufferlein, Thomas; Porzner, Marc; Becker, Thomas; Budach, Volker G.F.; Ceyhan, Güralp Onur; Esposito, Iréne; Fietkau, Rainer; Follmann, Markus; Friess, Helmut M.; Galle, Peter Robert; Geiler, M.; Glanemann, Matthias; Gress, Thomas Matthias; Heinemann, Volker; Hohenberger, Werner Max; Hopt, Ulrich Theodor; Izbicki, Jakob Robert; Klar, Ernst A.; Kleeff, J. H.; Kopp, Ina B.; Kullmann, Frank; Langer, T.; Langrehr, Jan Michael; Lerch, Markus M.; Löhr, Matthias J.; Lüttges, Jutta Elisabeth; Lutz, Manfred Paul; Mayerle, Julia V.; Michl, Patrick; Möller, Peter; Molls, Michael M.; Münter, Marc W.; Nothacker, Monika J.; Oettle, Helmut; Post, Stefan; Reinacher-Schick, Anke C.; Röcken, Christoph; Roeb, Elke; Saeger, Hans Detlev; Schmid, Roland Michael; Schmiegel, Wolff Helmut; Schoenberg, Michael H.; Siveke, Jens; Stuschke, Martin; Tannapfel, Andrea; Uhl, Waldemar H.; Unverzagt, Susanne; Van Oorschot, B.; Vashist, Yogesh Kumar; Werner, Jens; Yekebaş, Emre F.
    S3-Leitlinie zum exokrinen Pankreaskarzinom
    In: Zeitschrift für Gastroenterologie, Jg. 51, 2013, Nr. 12, S. 1395 – 1440
    DOI
  • Ardito, Christine M.; Grüner, Barbara M.; Takeuchi, Kenneth K.; Lubeseder-Martellato, Clara; Teichmann, Nicole; Mazur, Pawel K.; DelGiorno, Kathleen E.; Carpenter, Eileen S.; Halbrook, Christopher J.; Hall, Jason C.; Pal, Debjani; Briel, Thomas; Herner, Alexander; Trajkovic-Arsic, Marija; Sipos, Bence; Liou, Geou-Yarh; Storz, Peter; Murray, Nicole R.; Threadgill, David W.; Sibilia, Maria; Washington, M. Kay; Wilson, Carole L.; Schmid, Roland M.; Raines, Elaine W.; Crawford, Howard C.; Siveke, Jens T.
    EGF Receptor Is Required for KRAS-Induced Pancreatic Tumorigenesis
    In: Cancer Cell, Jg. 22, 2012, Nr. 3, S. 304 – 317
    DOI (Open Access)
  • Grüner, Barbara M.; Hahne, Hannes; Mazur, Pawel K.; Trajkovic-Arsic, Marija; Maier, Stefan; Esposito, Irene; Kalideris, Evdokia; Michalski, Christoph W.; Kleeff, Jörg; Rauser, Sandra; Schmid, Roland M.; Küster, Bernhard; Walch, Axel; Siveke, Jens T.
    MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer
    In: PLoS ONE, Jg. 7, 2012, Nr. 6, e39424
    DOI (Open Access)
  • Falkowska-Hansen, Berit; Kollar, Jasmin; Grüner, Barbara M.; Schanz, Merle; Boukamp, Petra; Siveke, Jens; Rethwilm, Axel; Kirschner, Marc
    An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cells
    In: Experimental Cell Research, Jg. 316, 2010, Nr. 11, S. 1885 – 1895
    DOI
  • Mazur, Pawel K.; Grüner, Barbara M.; Nakhai, Hassan; Sipos, Bence; Zimber-Strobl, Ursula; Strobl, Lothar J.; Radtke, Freddy; Schmid, Roland M.; Siveke, Jens T.
    Identification of epidermal pdx1 expression discloses different roles of notch1 and notch2 in murine krasG¹²D-induced skin carcinogenesis in vivo
    In: PLoS ONE, Jg. 5, 2010, Nr. 10, e13578
    DOI (Open Access)
  • Mazur, Pawel K.; Einwächter, Henrik; Lee, Marcel; Sipos, Bence; Nakhai, Hassan; Rad, Roland; Zimber-Strobl, Ursula; Strobl, Lothar J.; Radtke, Freddy; Klöppel, Günter; Schmid, Roland M.; Siveke, Jens T.
    Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 107, 2010, Nr. 30, S. 13438 – 13443
    DOI (Open Access)

    • Vorworte / Nachworte

  • Real, Francisco X.; Siveke, Jens T.
    Pancreatic cancer transcriptomes : molecular stratification in the adjuvant setting
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 32, 2021, Nr. 2, S. 133 – 135
    DOI (Open Access)

    • Abstracts

  • Pabst, Kim; Bartel, Timo; Sandach, Patrick; Weber, Manuel; Laschinsky, Christina; Eckstein, Markus; Kessler, Lukas; Kueper, Alina; Hadaschik, Boris; Kesch, Claudia; Hamacher, Rainer; Nader, Michael; Siveke, Jens; von Tresckow, Bastian; Kümmel, Sherko; Podleska, Lars; Reinacher-Schick, Anke; Uhl, Waldemar; Herrmann, Ken; Fendler, Wolfgang
    68Ga-FAPI-46 PET for Imaging of FAP-expressing Cancer : Results from a Prospective, Single-Arm, Interventional Phase 2 Clinical Trial
    In: Journal of Nuclear Medicine (JNM). New York: Springer, Jg. 66, 2025, Nr. Supplement 1, 251524
    Online Volltext (Open Access)
  • Trauger, Richard; Vile, Richard; Siveke, Jens T.; Liffers, Sven-Thorsten; Heineman, Thomas Charles; Coffey, Matt
    Role of pelareorep in activating anti-tumor immunity in PDAC
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 43, 2025, Nr. Suppl. 16, S. 2562 – 2562
    DOI (Open Access)
  • Ettrich, Thomas Jens; Seufferlein, Thomas; Betge, Johannes; Siveke, Jens T.; Reichert, Maximilian; Pelzer, Uwe; Reinacher-Schick, Anke C.; Uhl, Waldemar; Lindenmayer, Jessica; Perkhofer, Lukas; Kleger, Alexander
    UNITEPANC: Using organoids to predict efficacy of adjuvant treatment to improve outcome in resectable pancreatic cancer : Prospective, multicenter, proof-of-concept trial of the AIO Pancreatic Cancer Group
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 43, 2025, Nr. Suppl. 4, TPS791
    DOI (Open Access)
  • Ponz-Sarvise, M.; Gromke, Tanja; Magdalena, A. Landa; Richly, Heike; Liffers, S-T.; Kasper-Virchow, S.; Garonce-Hediger, R.; Alvarez, E. Castanon; Paredes, L. Ceniceros; Ortega, A. Chopitea; Siveke, Jens T.
    Chemo-immunotherapy combination of mFOLFOX6, bevacizumab and atezolizumab after first-line therapy for advanced biliary tract cancer : The COMBATBIL imCORE trial
    ESMO Congress 2024, 13-17 September 2024, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Suppl. 2, S. S229
    DOI
  • Barroux, M.; Househam, J.; Lakatos, E.; Ronel, T.; Baker, A-M.; Salié, H.; Mossner, M.; Jansen, M.; Caravagna, G.; Steiger, K.; Slotta-Huspenina, J.; Weichert, W.; Alberstmeier, M.; Chain, B.; Friess, H.; Bengsch, B.; Schmid, R.; Siveke, Jens T.; Quante, M.; Graham, T.
    Evolutionary and immune microenvironment dynamics determine response to neoadjuvant treatment of oesophageal adenocarcinoma
    ESMO Gastrointestinal Cancers Congress 2024, 26-29 June 2024, Munich, Germany,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Supplement 1, S. S168 – S169
    DOI
  • Lahusen, A.; Lutz, M.P.; Karthaus, M.; Kirchner, M.; Cheung, P.F.; Wisser, S.; Ansorge, N.; Barmashenko, G.; Hoefling, S.; Leidig, T.; Schulte, M.; Waldschmidt, D.T.; Budczies, J.; Siveke, Jens T.; Tannapfel, A.; Stenzinger, A.; Ettrich, T.J.; Eiseler, T.; Raeth, S.; Seufferlein, T.
    Exploratory biomarker analysis based on the PREDICT trial (AIO-PAK-0216) for response prediction to second-line nal-IRI/5-FU/FA chemotherapy (CTX) in metastatic PDAC patients (mPDAC Pts)
    ESMO Gastrointestinal Cancers Congress 2024, 26-29 June 2024, Munich, Germany,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Supplement 1, S. S155
    DOI
  • Mavroeidi, I.; Seyed Mohammad, T.W.; Webersinke, G.; Burghofer, J.; Piringer, G.; Kasper-Virchow, S.; Liffers, S-T.; Reichinger, A.; Kirchweger, P.; Heibl, S.; Hamacher, R.W.; Petzer, A.L.; Schuler, Martin H. H.; Prager, G.; Kersting, David M.; Treckmann, Jürgen-Walter; Schildhaus, Hans-Ulrich; Rumpold, H.; Siveke, Jens T.; Doleschal, B.
    Homologous recombination repair (HRR) deficiency in biliary tract cancers : Clinical implications in subsequent therapy lines and correlation with platinum sensitivity
    ESMO Gastrointestinal Cancers Congress 2024, 26-29 June 2024, Munich, Germany,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Supplement 1, S. S127
    DOI
  • Jo, Peter; Ghadimi, Michael; Pelzer, Uwe; Crede, Marie-Theres Andrea; Telgmann, Ralph; Seppanen, Hanna; Bratlie, Svein Olav; Besselink, Marc G.; Friede, Tim; Siveke, Jens T.
    METAPANC, intensified treatment in patients with oligometastatic pancreatic cancer : Multimodal surgical treatment versus systemic chemotherapy alone: A prospective randomized controlled multicenter phase III trial
    2024 ASCO Annual Meeting, 31 May - 04 June 2024, Chicago, Ill., USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 42, 2024, Nr. Suppl. 16, TPS4207
    DOI
  • Siveke, Jens T.; Sinn, M.; Dorman, K.; Siegler, G.M.; Seufferlein, T.; Trojan, J.; Waldschmidt, D.T.; Koenig, A.O.; Schipp, D.; Liffers, S-T.; Kunzmann, V.
    Nab-paclitaxel/gemcitabine with or without epigenetic targeting followed by consolidating immune targeting with durvalumab and lenalidomide in patients with advanced pancreatic ductal adenocarcinoma : Results from the SEPION/AIO-PAK-0118 phase I/II study
    ESMO Congress 2024, 13-17 September 2024, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Suppl. 2, S. S931
    DOI
  • Schlenk, R.F.; Rübsam, M.; Teleanu, M-V.; Richter, S.; Siveke, Jens T.; Wagner, S.; Kopp, H-G.; Kindler, T.; Illert, L.; Golf, A.H-E.; Dorman, K.; Schreck, N.; Benner, A.; Süsse, H.; Freitag, A.; von Kalle, C.; Glimm, H.; Hübschmann, D.; Fröhling, S.; Heilig, C.E.
    Randomized phase II study of trabectedin/olaparib compared to physician’s choice in subjects with previously treated advanced or recurrent solid tumors harboring DNA repair deficiencies
    ESMO Congress 2024, 13-17 September 2024, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Suppl. 2, S. S294
    DOI
  • Kasper-Virchow, Stefan; Hofheinz, R.D.; Stintzing, S.; Dechow, T.N.; Ettrich, T.J.; Sinn, M.; Roderburg, C.; Fischer von Weikersthal, L.; Graeven, U.; Mueller, C.; Meiler, J.; Stein, A.; Modest, D.P.; Pauligk, C.; Virchow, I.; Siveke, Jens T.; Al-Batran, S-E.; Schuler, Martin; Goetze, T.O.
    Randomized phase III trial of ramucirumab in combination with TAS102 (Trifluridin/Tipiracil) vs. TAS102 monotherapy in heavily pretreated metastatic colorectal cancer : The RAMTAS/IKF643 trial of the German AIO (AIO-KRK-0316)
    ESMO Congress 2024, 13-17 September 2024, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 35, 2024, Nr. Suppl. 2: Abstract Book of the ESMO Congress 2024, 13-17 September 2024, S. S1218
    DOI
  • Bartel, Timo; Fendler, Wolfgang; Pabst, Kim; Hirmas, Nader; Umutlu, Lale; Grafe, Hong; Praus, Christine; Nader, Michael; Podleska, Lars; Barbato, Francesco; Siveke, Jens; Herrmann, Ken; Grünwald, Viktor; Hamacher, Rainer
    68Ga-FAPI-46 PET for imaging of FAP expressing cancer - interim findings from a single-center prospective interventional single-arm clinical trial
    55th Annual Conference of the Society of Nuclear Medicine (SNMICON), November 16-19, 2023, Jodhpur, India,
    In: Journal of Nuclear Medicine (JNM). New York: Springer, Jg. 64, 2023, Nr. Suppl. 1, P706
  • Weiss, L.; Heinemann, V.; Fischer, L.; Gieseler, F.; Hoehler, T.; Mayerle, J.; Quietzsch, D.; Reinacher-Schick, A.; Schenk, M.; Seipelt, G.; Siveke, Jens; Stahl, Michael; Vehling-Kaiser, U.; Waldschmidt, D.; Dorman, K.; Zhang, D.; Westphalen, B.; Haas, M.; Boeck, S.
    Changes in the course of advanced pancreatic cancer treatment with systemic chemotherapy : A pooled analysis of five clinical trials from two decades of clinical research within the German AIO Study-Group
    ESMO 25th World Congress on Gastrointestinal Cancer 2023, 28 June - 1 July 2023, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 34, 2023, Nr. Supplement 1: Abstract Book of the ESMO 25th World Congress on Gastrointestinal Cancer 2023, Barcelona, Spain, 28 June - 1 July 2023, S. S164
    DOI (Open Access)
  • Pabst, Kim; Hamacher, Rainer; Schaarschmidt, Benedikt; Kessler, Lukas; Cheung, Phyllis; Liffers, Sven-Thorsten; Miera, Monika; Kostbade, Karina; Lanzafame, Helena; Mavroeidi, Ilektra; Hirmas, Nader; Costa, Pedro Fragoso; Nader, Michael; Bartel, Timo; Schuler, Martin; Bauer, Sebastian; Herrmann, Ken; Siveke, Jens; Schildhaus, Hans-Ulrich; Fendler, Wolfgang
    Fibroblast activation protein alpha (FAPα) directed imaging and radioligand therapy in patients with solitary fibrous tumor (SFT)
    55th Annual Conference of the Society of Nuclear Medicine (SNMICON), November 16-19, 2023, Jodhpur, India,
    In: Journal of Nuclear Medicine (JNM). New York: Springer, Jg. 64, 2023, Nr. Suppl. 1, P714
  • Watanabe, Masao; Grafe, Hong; Hirmas, N.; Hamacher, Rainer; Lanzafame, Helena; Pabst, Kim; Nader, Michael; Siveke, Jens T.; Fendler, Wolfgang P.; Herrmann, Ken; Weber, Manuel
    Head-to-head comparison of68Ga-FAPI46 PET/CT,18F-FDG PET/CT, and contrast- enhanced CT in patient with various solid tumors
    Annual Congress of the European Association of Nuclear Medicine, 9-13 September, 2023, Vienna, Austria,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 50, 2023, Nr. 1 supplement, S. S166 – S167
    DOI
  • Mavroeidi, I. A.; Reissig, T.; Kalbourtzis, S.; Liffers, S.-T.; Herold, T.; Treckmann, Jürgen-Walter; Schildhaus, Hans-Ulrich; Schuler, Martin; Siveke, Jens T.
    Molecular characterization of biliary tract cancer at a single comprehensive cancer center focusing on DNA damage repair genes
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 62
    DOI (Open Access)
  • Pabst, Kim; Hamacher, Rainer; Lanzafame, Helena; Mavroeidi, Ilektra-Antonia; Bartel, Timo; Nader, Michael; Bauer, Sebastian; Siveke, Jens T.; Weber, Manuel; Kersting, David; Jentzen, Walter; Ahrens, M.; Herrmann, Ken; Fragoso Costa, Pedro
    Occurence of hematotoxic side effects during 90Y-FAPI-46 radioligand therapy (RLT) in patients with advanced metastatic tumor diseases
    Annual Congress of the European Association of Nuclear Medicine, 9-13 September 2023 Vienna, Austria,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 50, 2023, Nr. 1 supplement, S. S671
    DOI (Open Access)
  • Albrecht, L. J.; Höwner, A.; Griewank, Klaus; Lueong, S. S.; von Neuhoff, N.; Horn, Peter A.; Sucker, A.; Paschen, Annette; Livingstone, Elisabeth; Ugurel, Selma; Zimmer, Lisa; Horn, S.; Siveke, Jens T.; Schadendorf, Dirk; Váraljai, R.; Rösch, Alexander
    Im Plasma zirkulierende zellfreie mRNA ermöglicht die minimal-invasive und Genotyp-unabhängige Therapieüberwachung bei Patienten mit Melanom
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 20, 2022, Nr. S3, S. 12 – 13
    DOI
  • Sivakumar, S.; Macarulla, T.; Grell, P.; Chee, C.; Krishnamurthy, A.; Ka Wong, M.; Michael, M.; Milella, M.; Prager, G.; Springfeld, C.; Collignon, J.; Siveke, Jens; Santoro, A.; Lin, C.; Peltola, K.; Bostel, G.; Jankovic, D.; Altzerinakou, M.; Fabre, C.; Bai, L.
    P-5 Phase II study (daNIS-1) of the anti-TGF-β monoclonal antibody (mAb) NIS793 +/- spartalizumab in combination with nab-paclitaxel/gemcitabine (NG) versus NG alone in patients with first-line metastatic pancreatic ductal adenocarcinoma (mPDAC)
    ESMO 24th World Congress on Gastrointestinal Cancer 2022, 29 June -2 July 2022, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 33, 2022, Nr. Suppl. 4, S. S247
    DOI (Open Access)
  • Heilig, C.E.; Teleanu, M-V.; Bhatti, I.A.; Richter, S.; Siveke, Jens T.; Wagner, S.; Kopp, H-G.; Kindler, T.; Illert, L.; Golf, A.; Dormann, K.; Benner, A.; Süsse, H.; Freitag, A.; Von Kalle, C.; Glimm, H.; Hübschmann, D.; Fröhling, S.; Schlenk, R.F.
    Randomized phase II study of trabectedin/olaparib compared to physician’s choice in subjects with previously treated advanced or recurrent solid tumors harboring DNA repair deficiencies
    Annual Meeting of the European-Society-for-Medical-Oncology (ESMO): SEP 09-13, 2022; Paris, France,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 33, 2022, Nr. Suppl. 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S762 – S763
    DOI (Open Access)
  • Hamacher, R.W.; Pabst, K.M.; Kessler, Lukas; Costa, Pedro Fragoso; Ferdinandus, J.; Weber, Manuel; Lippert, M.; Lückerath, Katharina; Hirmas, N.; Kostbade, K.; Mavroeidi, I.A.; Schuler, Martin H. H.; Ahrens, M.; Rischpler, Christoph; Bauer, Sebastian; Herrmann, Ken; Siveke, Jens T.; Fendler, Wolfgang P.
    Safety and efficacy of [90Y]Y-FAPI-46 radioligand therapy in patients with advanced sarcomas and other cancer entities
    ESMO Congress 2022, 9 - 13 September 2022, Paris, France,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 33, 2022, Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S1231 – S1232
    DOI (Open Access)
  • Tiwary, K.; Mader, S.; Hauff, S.; Valar, A.; Ditrich, T.; Zhang, X.; Kleger, A.; Seufferlein, T.; Sanz, B.; Siveke, Jens; Walter, K.; Hermann, P.C.
    Selective elimination of CD133+ cancer stem cells using novel BET/HDAC inhibitor TW09 as therapy for pancreatic ductal adenocarcinoma (PDAC)
    Molecular Analysis for Precision Oncology Congress 2022, 14-16 October 2022, Amsterdam, The Netherlands,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 33, 2022, Nr. Suppl. 8, S. S1411
    DOI (Open Access)
  • Pabst, K. M.; Trajkovic-Arsic, M.; Cheung, P. F.; Kessler, Lukas; Hirmas, N.; Nader, M.; Bartel, T.; Schaarschmidt, B. M.; Kasper, Stefan; Siveke, Jens T.; Hamacher, R.; Schmidt, H. H. J.; Ingenwerth, M.; Herrmann, Ken; Fendler, Wolfgang P.
    Superiority of [68Ga]Ga-FAPI-46 over [18F]F-FDG PET/CT for cholangiocarcinoma imaging
    EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022 Barcelona, Spain,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 49, 2022, Nr. Supplement 1, S. S192 – S193
    DOI (Open Access)
  • Hirmas, N.; Ingenwerth, M.; Sraieb, Miriam; Kessler, Lukas; Pabst, K. M.; Lanzafame, H.; Lückerath, Katharina; Kasper, Stefan; Nader, M.; Schildhaus, Hans-Ulrich; Hadaschik, Boris; Grünwald, Viktor; von Tresckow, Bastian; Hanoun, Christine; Aigner, Clemens; Glas, Martin; Herrmann, Ken; Siveke, Jens T.; Hamacher, R.; Fendler, Wolfgang P.
    Target Expression and FAP-Directed Tumour Imaging in a Large, Single-Centre PET Database of 324 Patients and 21 Tumour Entities
    EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022, Barcelona, Spain,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 49, 2022, Nr. Supplement 1, S. S119 – S120
    DOI (Open Access)
  • Kessler, Lukas; Ferdinandus, J.; Costa, P. F.; Weber, Manuel; Hirmas, N.; Kostbade, K.; Bauer, Sebastian; Dirksen, U.; Zarrad, F.; Nader, M.; Grafe, Hong; Chodyla, M.; Milosevic, A.; Umutlu, Lale; Schuler, Martin; Ahrens, M.; Podleska, Lars E.; Schildhaus, Hans-Ulrich; Rischpler, Christoph; Siveke, Jens T.; Herrmann, Ken; Fendler, Wolfgang P.; Hamacher, R.
    A novel theranostic approach for sarcoma : Insights on diagnostic and therapeutic use of FAP-radioligands
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 44, 2021, Nr. Supplement 2, S. 11 – 12
    DOI (Open Access)
  • Kessler, Lukas; Hamacher, Rainer; Ferdinandus, Justin; Zarrad, Fadi; Hirmas, Nader; Schildhaus, Hans-Ulrich; Siveke, Jens; Herrmann, Ken; Fendler, Wolfgang
    Ga-68-FAPI for sarcoma imaging : Data from the FAPI-PET prospective observational trial
    2021 SNMMI Annual Meeting, June 11th to June 15th, 2021, virtual,
    In: Journal of Nuclear Medicine (JNM). New York: Springer, Jg. 62, 2021, Nr. Suppl. 1, 126
    Online Volltext
  • Ferdinandus, J.; Fragoso Costa, Pedro; Kessler, Lukas; Weber, Manuel; Hirmas, N.; Kostbade, Karina; Bauer, Sebastian; Schuler, Martin; Ahrens, M.; Schildhaus, Hans-Ulrich; Rischpler, Christoph; Siveke, Jens T.; Herrmann, Ken; Fendler, Wolfgang P.; Hamacher, R.
    Initial clinical experience with [Y-90]Y-FAPI-46 radioligand therapy for advanced stage solid tumors
    Annual Congress of the European Association of Nuclear Medicine, October 20-23, 2021, Virtual,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 48, 2021, Nr. Suppl. 1, S. S290
    DOI (Open Access)
  • Kasper, Stefan; Goetze, Thorsten Oliver; Stintzing, Sebastian; Hofheinz, Ralf Dieter; Sinn, Marianne; Dechow, Tobias Nicolaas; Ettrich, Thomas Jens; Keitel, Verena; Graeven, Ullrich; Fischer von Weikersthal, Ludwig; Kolov, Alexander; Edelmann, Thomas; Stein, Alexander; Trarbach, Tanja; Junge, Sabine; Pauligk, Claudia; Virchow, Isabel; Siveke, Jens T.; Al-Batran, Salah-Eddin; Schuler, Martin
    RAMucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic colorectal cancer : Safety results from the phase IIb part of the RAMTAS phase II/III trial of the German AIO (AIO-KRK-0316)
    2021 ASCO Annual Meeting, June 4-8, 2021, virtual,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 39, 2021, Nr. 15_Suppl, 3566
    DOI (Open Access)
  • Horak, Peter; Heining, Christoph; Mock, Andreas; Siveke, Jens; Bauer, Sebastian; Fröhling, Stefan; German Cancer Consortium (DKTK)
    Comprehensive genomic analysis of rare cancers : Results of the MASTER precision oncology trial of the German Cancer Consortium
    AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, USA,
    In: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 80, 2020, Nr. Suppl. 16, 821
    DOI (Open Access)
  • Patnana, Pradeep Kumar; Behrens, M.; Klotz, L.; Liebmann, M.; Frank, D.; Nimmagadda, C.; Siveke, Jens; Trajkovic-Arsic, Marija; Hanenberg, Helmut; Thivakaran, Aniththa; Khandanpour, Cyrus
    Growth factor independence 1 expression induced metabolic vulnerabilities and presents novel therapeutic opportunities in acute myeloid leukemia
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 43 – 44
    DOI (Open Access)
  • Kasper, Stefan; zur Hausen, Gerrit; Stein, Alexander; Stintzing, Sebastian; Berger, Andreas; Loges, Sonja; Hofheinz, Ralf; Trarbach, Tanja; Graeven, Ullrich; Fischer von Weikersthal, Ludwig; Goetze, Thorsten Oliver; Hagen, Volker A.; Burock, Susen; Hoffmeister, Albrecht; Dechow, Tobias Nicolaas; Pauligk, Claudia; Virchow, Isabel; Siveke, Jens T.; Al-Batran, Salah-Eddin; Schuler, Martin
    A phase IIb study of ramucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic, chemotherapy refractory colorectal cancer patients : The RAMTAS trial of the German AIO (KRK-0316)
    2019 ASCO Annual Meeting, May 31-June 4, 2019, Chicago, Ill., USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 37, 2019, Nr. 15, TPS3617
    DOI (Open Access)
  • Lorenzen, Sylvie; Quante, Michael; Rauscher, Isabel; Slotta-Huspenina, Julia; Becker, Karl Friedrich; Weichert, Wilko; Feith, Marcus; Friess, Helmut; Combs, Stephanie E.; Weber, Wolfgang; Haller, Bernhard; Angele, Martin K.; Albertsmeier, Markus; Blankenstein, Christiane; Kasper, Stefan; Zimmermann, Jens Peter; Algül, Hana; Schmid, Roland M.; Schwaiger, Markus; Siveke, Jens T.
    PET-directed combined modality therapy for gastroesophageal junction cancer : First results of the prospective MEMORI trial
    2019 ASCO Annual Meeting, May 31-June 4, 2019, Chicago, Ill., USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 37, 2019, Nr. 15, 4018
    DOI (Open Access)
  • Smeets, E.M.M.; Feuerecker, B.; Teuwen, J.; van der Laak, J.; Gotthardt, M.; Siveke, Jens; Braren, R.; Ciompi, F.; Aarntzen, E.
    Metabolic heterogeneity as a PET-biomarker predicts overall survival of pancreatic cancer patients
    Annual Congress of the European Association of Nuclear Medicine, EANM'18, October, 13 – 17, 2018, Düsseldorf, Germany,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 45, 2018, Nr. Suppl. 1, S. 97
    DOI
  • Kunzmann, Volker; Martens, Uwe Marc; Alguel, Hana; Siveke, Jens T.; Goekkurt, Eray; Pelzer, Uwe; Siegler, Gabriele Margareta; Hennes, Elke; Waldschmidt, Dirk; Jakobs, Ralf; Ferenczy, Peter; Keller, Ralph; Boeck, Stefan Hubert; Kullmann, Frank; Kapp, Markus; Germer, Christoph Thomas
    Secondary resectability in locally advanced pancreatic cancer (LAPC) after nab-paclitaxel/gemcitabine- versus FOLFIRINOX-based induction chemotherapy : Interim results of a randomized phase II AIO trial (NEOLAP)
    ASCO Gastrointestinal Cancers Symposium 2018, January 18-20, 2018, San Francisco, CA, USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 36, 2018, Nr. 4_suppl, 348
    DOI (Open Access)
  • Mercade Macarulla, Teresa; Hubner, R.; Blanc, J. F.; Wang-Gillam, A.; Li, C. P.; Bodoky, G.; Dean, A. P.; Yanshen, S.; Jameson, G. S.; Lee, K. H.; Chiu, C. F.; Schwartsmann, G.; Braiteh, F. S.; Cunningham, D.; Chen, L. T.; Von Hoff, D. D.; Mamlouk, K. K.; de Jong, F. A.; Siveke, Jens T.
    Subgroup analysis by baseline (BL) weight-associated parameters : A phase III study of liposomal irinotecan (nal-IRI)+/--5fluorouracil/leucovorin (5-FU/LV) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC) previously treated with g
    ASCO Gastrointestinal Cancers Symposium 2018, January 18-20, 2018, San Francisco, CA, USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 36, 2018, Nr. Suppl. 4, 410
    DOI (Open Access)
  • Mercade Macarulla, Teresa; Siveke, Jens T.; Dean, A. P.; Hubner, R.; Blanc, J. F.; Cunningham, D.; Chen, L. T.; Mirakhur, B.; Chen, J.; de Jong, F. A.; Wang-Gillam, A.
    Subgroup analysis by baseline pain intensity (BPI) and analgesic use (BAU) in NAPOLI-1 : A phase III study of liposomal irinotecan (nal IRI)+/- 5-fluorouracil/leucovorin (5-FU/LV) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC) p
    ASCO Gastrointestinal Cancers Symposium 2018, January 18-20, 2018, San Francisco, CA, USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 36, 2018, Nr. Suppl. 4, 379
    DOI (Open Access)
  • Siveke, Jens T.; Hubner, R.; Mercade Macarulla, Teresa; Wang-Gillam, A.; Dean, A. P.; Blanc, J. F.; Cunningham, D.; Mirakhur, B.; Belanger, B.; de Jong, F. A.; Chen, L. T.
    Subgroup analysis by measurable metastatic lesion (ML) number and selected lesion locations (LL) at baseline (BL) in NAPOLI-1 : A phase III study of liposomal irinotecan (nal-IRI)+/- 5-fluorouracil/leucovorin (5-FU/LV) in patients (pts) with metastatic pan
    ASCO Gastrointestinal Cancers Symposium 2018, January 18-20, 2018, San Francisco, CA, USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 36, 2018, Nr. Suppl. 4, 460
    DOI (Open Access)
  • Heid, I.; Steiger, K.; Trajkovic-Arsic, M.; Settles, M.; Eißwein, M.; Erkan, M.; Kleeff, J.; Jäger, C.; Friess, H.; Haller, B.; Steingötter, A.; Schmid, R.; Schwaiger, M.; Rummeny, E.; Esposito, I.; Siveke, Jens; Braren, R.
    Co-clinical assessment of tumor cellularity in pancreatic cancer
    Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 175
    DOI
  • Siveke, Jens T.; Chen, L. T.; Von Hoff, D. D.; Li, C.-P.; Wang-Gillam, A.; Bodoky, G.; Dean, A.; Shan, Y. S.; Jameson, G.; Macarulla, T.; Lee, K. H.; Cunningham, D.; Blanc, J. F.; Hubner, R. A.; Chiu, C. F.; Schwartsmann, G.; Braiteh, F.; Moyo, V.; Belanger, B.; Bayever, E.
    Expanded analyses of NAPOLI-1 : Phase 3 study of nal-IRI (MM-398), with or without 5-fluorouracil (5FU) and leucovorin (LV), versus 5-fluorouracil and leucovorin (5FU/LV), in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based the
    Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 170
    DOI
  • Neff, F.; Kirsch, D. G.; Saur, D.; Schmid, R. M.; Bazhin, A.; Heikenwälder, M. F.; Siveke, Jens T.
    Targeting notch for myeloid reprogramming in pancreatic cancer
    Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 16
    DOI
  • Bitzer, M.; Ganten, T. M.; Woerns, M. A.; Siveke, Jens T.; Dollinger, M. M.; Scheulen, Max Ernst; Wege, H.; Giannini, E. G.; Cillo, U.; Trevisani, F.; Santoro, A.; Montesarchio, V.; Mais, A.; Hauns, B.; Asche, J.; Herz, T.; Pegoraro, S.; Ammendola, A.; Henning, S. W.; Hentsch, B.; SHELTER Study Grp
    Resminostat in advanced hepatocellular carcinoma (HCC) : Overall survival subgroup analysis of prognostic factors in the SHELTER trial
    2013 ASCO Annual Meeting, 30 May - 3 Jun 2013, Chicago, Ill., USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 31, 2013, Nr. 15 Suppl., e15088
    DOI

    • Preprints

  • Egetemaier, Stefanie; Chauvistré, Heike; Váraljai, Renáta; Hua, Yichao; Lueong, Smiths; Makhzami, Samira; Srinivas, Nalini; Forster, Jan; Ullrich, Vivien; Stupia, Simone; Schroeder, Valéria; Scharfenberg, Sarah; Hoewner, Anna; Shannan, Batool; Siveke, Jens; Baietti, Maria Francesca; Leucci, Eleonora; Marine, Jean-Christophe; Paschen, Annette; Scheffler, Björn; Engel, Daniel R.; Becker, Lisa; Nensa, Felix; Köster, Johannes; Grünwald, Barbara; Poepsel, Simon; Ninck, Sabrina; Kaschani, Farnusch; Schadendorf, Dirk; Becker, Jürgen; Tasdogan, Alpaslan; Rambow, Florian; Rösch, Alexander
    Redirecting resistance evolution in BRAFV600 melanoma by inhibition of the peroxiredoxin-thioredoxin system
    2025
    DOI (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Pijnappel, E.N.; Suurmeijer, J.A.; Koerkamp, B. Groot; Siveke, Jens; Salvia, R.; Ghaneh, P.; Besselink, Marc G.; Wilmink, J.W.; van Laarhoven, H.W.M.
    Mandatory Reporting Measurements in Trials for Potentially Resectable Pancreatic Cancer
    In: Textbook of Pancreatic Cancer: Principles and Practice of Surgical Oncology / Søreide, Kjetil; Stättner, Stefan (Hrsg.). Cham: Springer Science+Business Media, 2021, S. 107 – 118
    DOI

    • Poster / Posterbeiträge

  • Pabst, Kim M.; Bartel, Timo; Sandach, Patrick; Laschinsky, Christina; Weber, Manuel M.; Kessler, Lukas; Küper, Alina T.; Hadaschik, Boris A.; Kesch, Claudia; Hamacher, Rainer; Kasper, Stefan; Podleska, Lars E.; Siveke, Jens T.; Eckstein, Markus; von Tresckow, Bastian; Kuemmel, Sherko; Reinacher-Schick, Anke; Uhl, Waldemar; Herrmann, Ken; Fendler, Wolfgang P.
    68Ga-FAPI-46 PET/CT for cancer imaging : Results of a single-center, prospective, interventional, single-arm clinical trial
    2025 ASCO Genitourinary Cancers Symposium, February 13-15, 2025, San Francisco, CA, USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 43, 2025, Nr. 5, Supplement, 457
    DOI
  • Lanzafame, Helena; Hamacher, Rainer; Mavroeidi, Ilektra-Antonia; Pabst, Kim; Hirmas, Nader; Kessler, Lukas; Bartel, Timo; Leyser, Stephan; Barbato, Francesco; Schuler, Martin; Bauer, Sebastian; Siveke, Jens T.; Herrmann, Ken; Fendler, Wolfgang P.
    68Ga-FAPI PET/CT novel diagnostic tool in sarcoma
    Annual Congress of the European Association of Nuclear Medicine, 9-13 September, 2023, Vienna, Austria,
    In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 50, 2023, Nr. 1 supplement, S. S414 – S415
    DOI
  • Mavroeidi, I.; Reissig, T.; Kalbourtzis, S.; Liffers, S-T.; Herold, T.; Kasper-Virchow, S.; Schildhaus, Hans-Ulrich; Schuler, Martin H. H.; Siveke, Jens
    DNA damage repair pathways in biliary tract cancer : A new target for precision medicine?
    ESMO Congress 2023 ; 20 - 24 October 2023, Madrid, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 34, 2023, Nr. Supplement 2: Abstract Book of the ESMO Congress 2023, 20 - 24 October 2023, S. S223
    DOI (Open Access)
  • Dorman, K.; Heinemann, V.; Snijder, R. J.; Waldschmidt, D. T.; Freiberg-Richter, J.; Siveke, Jens T.; Fischer von Weikersthal, L.; Reinacher-Schick, A.; Schenk, M.; Mayerle, J.; Caca, K.; Stahl, Michael; Kullmann, F.; Zhang, D.; Held, S.; Abdul-Ahad, A.; von Bergwelt-Baildon, M.; Boeck, S.; Haas, M.
    Analyse zweier prospektiver klinischer Studien der Arbeitsgemeinschaft Internistische Onkologie mit der “Burden of Therapy” (BOTh®TM) Methode : einem neuen Instrument zur Evaluation unerwünschter Ereignisse beim metastasierten Pankreaskarzinom
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 295
    DOI (Open Access)
  • Salama, A.K.S.; Cheshuk, V.; Siveke, Jens; Berrocal, A.; Abdullah, S.E.; Lockwood, S.; McCully, M.L.; Kee, D.
    Characterization of cytokine release syndrome (CRS) following treatment with tebentafusp in previously untreated patients with metastatic uveal melanoma
    ESMO Congress 2021, 16 – 21 September 2021, virtual,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 32, 2021, Nr. Suppl. 5, S. S855
    DOI (Open Access)
  • Hartlapp, I.; Valta-Seufzer, D.; Siveke, Jens; Algül, H.; Goekkurt, E.; Siegler, G.M.; Martens, U.M.; Waldschmidt, D.; Pelzer, U.; Fuchs, M.; Kullmann, F.; Boeck, S.; Ettrich, T.J.; Held, S.; Keller, R.; Anger, F.; Germer, C-T.; Stang, H.A.; Heinemann, V.; Kunzmann, V.
    Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multi-agent induction chemotherapy : Results from a prospective, multicenter phase II trial (NEOLAP-AIO-PAK-0113)
    ESMO Congress 2021, 16 – 21 September 2021, virtual,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 32, 2021, Nr. Suppl. 5, S. S1091
    DOI (Open Access)
  • Behrens, Diana; Lawlor, Rita T.; Heeschen, Christopher; Buettner, B.; Siveke, Jens; Hoffmann, Jens
    Correlation of molecular profiles with response to targeted drugs in pancreatic cancer models
    32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, 24-25 October 2020, Virtual Conference,
    In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 138, 2020, Nr. Supplement 2, S. S58 – S59
    DOI
  • Kasper, Stefan; Hofheinz, R.D.; Stintzing, S.; Götze, T.O.; Sinn, M.; Dechow, T.; Ettrich, T.J.; Keitel, V.; Graeven, U.; Fischer von Weikersthal, L.; Kolov, A.; Edelmann, T.; Stein, A.; Trarbach, T.; Junge, S.; Pauligk, C.; Virchow, I.; Siveke, Jens; Al-Batran, S-E.; Schuler, Martin
    Interim safety analysis of the phase IIb study of ramucirumab in combination with TAS102 vs. TAS102 monotherapy in metastatic colorectal cancer : The RAMTAS trial of the German AIO
    ESMO Virtual Congress 2020, 19 – 21 September / 16 – 18 October 2020,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 31, 2020, Nr. Suppl. 4, S. S427 – S428
    DOI (Open Access)
  • Johansson, Patricia; Dierichs, L.; Klein-Hitpaß, Ludger; Bergmann, A.; Menninger, S.; Habenberger, P.; Klebl, B.; Siveke, Jens; Dührsen, U.; Choidas, A.; Dürig, Jan
    Anti-leukemic activity through CDK9 inhibition in T-cell prolymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 42, 2019, Nr. Supplement 4: Abstracts, S. 218
    DOI (Open Access)
  • Horak, Peter; Heining, Christoph; Kreutzfeldt, Simon; Heilig, Christoph E.; Möhrmann, Lino; Gieldon, Laura; Fröhlich, Martina; Uhrig, Sebastian; Hübschmann, Daniel; Beck, Katja; Richter, Daniela; Wolf, Stephan; Pfütze, Katrin; Geörg, Christina; Meißburger, Bettina; Klauschen, Frederick; Ochsenreither, Sebastian; Folprecht, Gunnar; Siveke, Jens; Bauer, Sebastian; Kindler, Thomas; Brandts, Christian; Börries, Melanie; Bubnoff, Nikolas von; Spiekermann, Karsten; Jost, Philipp J.; Schulze-Osthoff, Klaus; Bitzer, Michael; Schirmacher, Peter; Kalle, Christof von; Schlenk, Richard; Klink, Barbara; Hutter, Barbara; Weichert, Wilko; Stenzinger, Albrecht; Schröck, Evelin; Brors, Benedikt; Glimm, Hanno; Fröhling, Stefan
    Clinical relevance of comprehensive genomic analysis in advanced-stage cancers and rare malignancies : Results from the MASTER trial of the German Cancer Consortium
    AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, USA,
    In: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 79, 2019, Nr. 13, Suppl., 468
    DOI (Open Access)
  • Dantes, Z.; Hennig, A.; Wirth, M.; Feldmann, K.; Engleitner, T.; Lange, S.; Öllinger, R.; Muckenhuber, A.; Yen, H.-Y.; Steiger, K.; Dantes, M.; Strobel, O.; Braren, Rickmer; Welsch, T.; Martignoni, M.; Ceyhan, G. O.; Weichert, W.; Rustgi, A.; Siveke, Jens; Stange, Daniel; Schmid, R. M.; Rad, R.; Schneider, G.; Reichert, M.
    Advanced organoid culture technology in pancreatic cancer and its translational applications
    33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 206
    DOI (Open Access)
  • Schlenk, Richard; Barth, T.; Gröschel, S.; Heilig, C.; Folprecht, Gunnar; Richter, S.; Mayer-Steinacker, R.; Markus, S.; Möller, P.; Bauer, Sebastian; Siveke, Jens; Dettmer, S.; Richter, D.; Heining, C.; Horak, P.; Jäger, D.; Glimm, H.; Kalle, Christof von; Fröhling, S.
    CDK4/6 inhibition in locally advanced/metastatic chordoma (NCT-PMO-1601)
    33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 1, S. 156
    DOI (Open Access)
  • Lee, K.; Bodoky, Gyorgy; Blanc, Jean Frédéric; Siveke, Jens; Macarulla Mercade, T.; Wang-Gillam, Andrew; Chen, L.; Mirakhur, Beloo; Chen, Jie; De Jong, Floris
    Decreased appetite (DA) at baseline impacts prognosis in the NAPOLI-1 phase 3 study in metastatic pancreatic ductal adenocarcinoma (mPDAC)
    ESMO 20th World Congress on Gastrointestinal Cancer, 20–23 June 2018, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 5, S. v42 – v43
    DOI (Open Access)
  • Chen, Li Tzon; Macarulla, Teresa M.; Blanc, Jean Frédéric; Mirakhur, Beloo; Jong, Floris A. de; Belanger, Bruce; Bekaii-Saab, Tanios; Siveke, Jens
    Impact of dose reduction or dose delay on the efficacy of liposomal irinotecan (nal-IRI)+5-fluorouracil/leucovorin (5-FU/LV) : Survival analysis from NAPOLI-1
    43rd ESMO Congress (ESMO 2018), 19–23 October 2018, Munich, Germany,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 8, S. viii250 – viii251
    DOI (Open Access)
  • Macarulla Mercade, Teresa; Bodoky, Gyorgy; Siveke, Jens; Lee, Kyung-hun; Chen, J.; Mirakhur, Beloo; Dean, Andrew; Chen, Li-Tzong; Jong, Floris A. de
    NAPOLI-1 phase III trial outcomes by prior surgery, and disease stage, in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC)
    43rd ESMO Congress (ESMO 2018), 19–23 October 2018, Munich, Germany,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 8, S. viii249 – viii250
    DOI (Open Access)
  • Behrens, Diana; Büttner, Britta; Lawlor, Rita L.; Heeschen, Christopher; Buchholz, Malte; Siveke, Jens; Wengner, Antje M.; Saluja, Ashok; Hoffmann, Jens
    Preclinical evaluation of novel treatment strategies in patient-derived xenograft (PDX) models of pancreatic cancer
    AACR Annual Meeting 2018, April 14-18, 2018, Chicago, Ill., USA,
    In: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 78, 2018, Nr. Suppl. 13, 4093
    DOI (Open Access)
  • Behrens, D.; Lawlor, R. T.; Heeschen, C.; Buchholz, M.; Siveke, Jens; Wengner, A.; Saluja, A.; Buettner, B.; Hoffmann, J.
    Preclinical evaluation of novel treatment strategies in patient-derived xenograft (PDX) models of pancreatic cancer
    30th EORTC – NCI – AACR Symposium; 13 Nov - 16 Nov 2018; Dublin, Ireland,
    In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 103, 2018, Nr. Supplement 1, S. e101
    DOI
  • Macarulla Mercadé, Teresa; Wang-Gillam, Andrea; Chen, L.; Blanc, Jean Frédéric; Lee, K.; Bodoky, Gyorgy; Dean, Andrew; Siveke, Jens; Mirakhur, Beloo; Chen, J.; de Jong, F.
    Prognostic effect of primary tumor location in the NAPOLI-1 phase 3 study in metastatic pancreatic ductal adenocarcinoma (mPDAC)
    ESMO 20th World Congress on Gastrointestinal Cancer, 20–23 June 2018, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 5, S. v41 – v42
    DOI (Open Access)
  • Lakatos, Gábor; Lee, K.; Siveke, Jens; Blanc, Jean Frédéric; Macarulla Mercadé, Teresa; Dean, Andrew; Bodoky, Gyorgy; Mirakhur, Beloo; Chen, Jie; Wang-Gillam, Andrea; Chen, Li Li; Jong, Floris A. de
    Prognostic value of baseline biliary stents on outcomes in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) in the NAPOLI-1 trial
    ESMO 20th World Congress on Gastrointestinal Cancer, 20–23 June 2018, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 5, S. v42
    DOI (Open Access)
  • Macurulla Mercade, Teresa; Wang-Gillam, Andrea; Chen, L.; Blanc, Jean Frédéric; Lee, K.; Bodoky, Gyorgy; Dean, Andrew; Chen, Jie; Mirakhur, Beloo; Siveke, Jens; de Jong, Floris A.
    The effect of best response to prior anticancer therapy on efficacy outcomes in the NAPOLI-1 trial of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) previously treated with gemcitabine-based therapy
    ESMO 20th World Congress on Gastrointestinal Cancer, 20–23 June 2018, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 5, S. v42
    DOI (Open Access)
  • Chen, Li Tzon; Macarulla, Teresa M.; Belanger, Bruce; Mirakhur, Beloo; Jong, Floris A. de; Siveke, Jens
    The prognostic value of the modified glasgow prognostic score (mGPS) in predicting overall survival (OS) in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) receiving liposomal irinotecan (nal-IRI)+5-fluorouracil and leucovorin (5-FU/LV)
    43rd ESMO Congress (ESMO 2018), 19–23 October 2018, Munich, Germany,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 29, 2018, Nr. Suppl. 8, S. viii255 – viii256
    DOI (Open Access)
  • Fröhling, S.; Barth, T. F.; Groschel, S.; Folprecht, G.; Richter, S.; Mayer-Steinacker, R.; Schultheiss, M.; Möller, P.; Bauer, S.; Siveke, Jens T.; Dettmer, S.; Richter, D.; Heining, C.; Horak, P.; Glimm, H.; Jäger, D.; Von Kalle, C.; Schlenk, R.
    CDK4/6 inhibition in locally advanced/metastatic chordoma (NCT PMO-1601)
    42nd ESMO Congress (ESMO 2017), 8-12 September 2017, Madrid, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 28, 2017, Nr. Suppl. 5, S. v538
    DOI
  • Hubner, R. A.; Chen, L. T.; Li, C. P.; Bodoky, G.; Dean, A.; Lee, K. H.; Cunningham, D.; Siveke, Jens T.; Braiteh, F. S.; de Jong, F. A.; Belanger, B.; Walls, R.; Mody, P. D.; von Hoff, D. D.; Wang-Gillam, A.
    Prognostic value of baseline neutrophil-to-lymphocyte ratio for predicting clinical outcome in metastatic pancreatic ductal adenocarcinoma (mPDAC) patients treated with liposomal irinotecan (nal-IRI) + 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV alone
    42nd ESMO Congress (ESMO 2017), 8-12 September 2017, Madrid, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 28, 2017, Nr. Suppl. 5, S. v253
    DOI
  • Siveke, Jens T.; Cubillo, A.; Blanc, J. F.; Melisi, D.; Von Hoff, D. D.; Wang-Gillam, A.; Chen, L. T.; Becker, C.; Mamlouk, K.; Belanger, B.; Yang, Y.; de Jong, F.; Hubner, R.
    Effects of nanoliposomal irinotecan (nal-IRI;MM-398) +/- 5-Fluorouracil and leucavorin (5-FU/LV) on quality of life (QoL) in NAPOLI-1 : a phase 3 study in patients (pts) with metastatic pancreatic adenocarcinoma (mPAC) previously treated with gemcitabine-b
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 14.–18. Oktober 2016, Leipzig, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 3, S. 259
    DOI
  • Chen, L-T.; Dean, A.; Macarulla, T.; Belanger, B.; Cunningham, D.; Li, C-P.; Hubner, R.; Jameson, G.S.; Siveke, Jens T.; Wang-Gillam, A.; Lee, K-H.; von Hoff, D.D.; Bodoky, G.; Chiu, C-F.; Bayever, E.; Blanc, J-F.; Schwartsmann, G.; de Jong, F.; Shan, Y-S.; Braiteh, F.
    Final results of NAPOLI-1 : A phase 3 study of nal-IRI (MM-398) ± 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
    41st ESMO Congress (ESMO 2016), 7-11 October 2016, Copenhagen, Denmark,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 27, 2016, Nr. Suppl. 6, S. vi211
    DOI
  • Heid, I.; Trajkovic-Arsic, M.; Steiger, K.; Settles, M.; Steingotter, A.; Gupta, A.; Lubeseder-Martellato, C.; Schmid, R. M.; Rummeny, E.; Siveke, Jens; Braren, R.
    Gemcitabine impairs tumor perfusion in stroma rich murine endogenous PDAC
    28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, November 29 to December 2, 2016, Munich, Germany,
    In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 69, 2016, Nr. Suppl. 1, S. S67 – S68
    DOI
  • Trajkovic-Arsic, M.; Kalideris, E.; Sun, N.; Feuchtinger, A.; Gupta, A.; Aichler, M.; Schmid, R. M.; Walch, A.; Siveke, Jens T.
    Identification of metabolic changes in Pancreatic Ductal Adenocarcinoma
    Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ, 32. Deutscher Krebskongress, 24.-27. Februar 2016, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 76 – 77
    DOI
  • Kamyabi-Moghaddam, Z.; Wirth, M.; Babucke, M.; Blume, K.; Saur, D.; Schorn, S.; Martignoni, M. E.; Ceyhan, G.; Schmid, R. M.; Siveke, Jens T.; Schneider, G.; Reichert, M.
    Patient-derived organoids to model intra- and intertumoral heterogeneity of pancreatic cancer in high-throughput drug screens
    Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 162
    DOI
  • Pelzer, U.; Blanc, J. F.; Melisi, D.; Cubillo, A.; Von Hoff, D. D.; Wang-Gillam, A.; Chen, L. T.; Siveke, Jens T.; Wan, Y.; Solem, C. T.; Botteman, M.; Yang, Y.; de Jong, F.; Hubner, R.
    Quality-adjusted time without symptoms or toxicity (Q-TWIST) of nanoliposomal irinotecan (nal-IRI;MM-398) plus 5-fluorouracil and leucavorin (5-FU/LV) vs 5-FU/LV alone in patients with metastatic pancreatic adenocarcinoma (mPAC) previously treated with ge
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 14.–18. Oktober 2016, Leipzig, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 3, S. 260
    DOI
  • Heid, I.; Lubeseder-Martellato, C.; Trajkovic-Arsic, M.; Rummeny, E.; Steiger, K.; Schmid, R. M.; Braren, R.; Siveke, Jens
    RAC1 activity is necessary for the development of murine undifferentiated PDAC
    28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, November 29 to December 2, 2016, Munich, Germany,
    In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 69, 2016, Nr. Suppl. 1, S. 140
    DOI
  • Wang-Gillam, A.; Belanger, B.; Jameson, G.S.; Li, C-P.; Mamlouk, K.; Cunningham, D.; Bodoky, G.; de Jong, F.; Hubner, R.A.; von Hoff, D.D.; Chiu, C-F.; Blanc, J-F.; Shan, Y-S.; Dean, A.; Lee, K-H.; Chen, L-T.; Schwartsmann, G.; Macarulla, T.; Braiteh, F.; Siveke, Jens T.
    Time course of selected treatment emergent adverse events (TEAEs) in NAPOLI-1 : A phase 3 study of nal-IRI (MM-398) ± 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
    41st ESMO Congress (ESMO 2016), 7-11 October 2016, Copenhagen, Denmark,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 27, 2016, Nr. Suppl. 6, S. vi234
    DOI
  • Trajkovic-Arsic, M.; Heid, I.; Steiger, K.; Gupta, A.; Fingerle, A.; Wörner, C.; Teichmann, N.; Wenzel, P.; Herner, A.; Steingötter, A.; Beer, A.; Schweiger, M.; Settles, M.; Haller, B.; Esposito, I.; Rummeny, E.; Schmid, R. M.; Braren, R.; Siveke, Jens T.
    Use of Diffusion-weighted magnetic resonance imaging for therapy response evaluation in pancreatic cancer
    Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 113 – 114
    DOI
  • Moehler, M.; Thuss-Patience, P.; Schmoll, H. J.; Hegewisch-Becker, S.; Wilke, Hansjochen; Al-Batran, S. E.; Weissinger, F.; Kullmann, F.; von Weikerstahl, L. F.; Siveke, Jens T.; Kanzler, S.; Schimanski, C. C.; Otte, M.; Schollenberger, L.; Koenig, J.; Galle, P. R.
    Na-Folfiri plus sunitinib versus Na-Folfiri alone in advanced chemorefractory esophagogastric cancer patients : A randomized double-blinded placebo-controlled multicentric AIO phase II trial
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,
    In: Onkologie. Basel: Karger, Jg. 36, 2013, Nr. Suppl. 7, S. 74
    DOI
  • Bitzer, Michael; Horger, Markus; Ganten, Tom; Ebert, Matthias P.; Siveke, Jens T.; Woerns, Marcus A.; Dollinger, Matthias M.; Gerken, Guido; Scheulen, Max Ernst; Mais, Anna; Jankowsky, Rüdiger; Hauns, Bernhard; Hentsch, Bernd; Lauer, Ulrich M.
    Clinical update on the phase I/II trial of HDAC inhibitor resminostat in patients with sorafenib-resistant hepatocellular carcinoma (HCC) - The Shelter Study
    13th World Congress on Gastrointestinal Cancer 22–25 June 2011, Barcelona, Spain,
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 22, 2011, Nr. Suppl. 5, S. v76 – v76
    DOI