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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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AK2-Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack ErythropoiesisIn: European Journal of Immunology, Jg. 55, 2025, Nr. 7, e51466DOI (Open Access)
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Aldolase A : the broker of glycolysis: Cancer metabolismIn: Nature Metabolism, 2025, Nr. 7, S. 242 – 244
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Approaches to stable isotope tracing and in vivo metabolomics in the cancer clinicIn: The EMBO Journal, Jg. 44, 2025, Nr. 12, S. 3303 – 3306DOI (Open Access)
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Aspartate signalling drives lung metastasis via alternative translationIn: Nature, Jg. 638, 2025, Nr. 2, S. 244 – 250
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Changes in tumor and cardiac metabolism upon immune checkpointIn: Basic Research in Cardiology, Jg. 120, 2025, Nr. 1, S. 133 – 152DOI (Open Access)
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Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistanceIn: Nature Communications, Jg. 16, 2025, Nr. 1, 5387DOI (Open Access)
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Deep imaging of LepR⁺ stromal cells in optically cleared murine bone hemisectionsIn: Bone Research, Jg. 13, 2025, Nr. 1, 6DOI (Open Access)
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High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non-Small Cell Lung Cancer in PatientsIn: Cancer Discovery, Jg. 15, 2025, Nr. 4, S. 702 – 716DOI (Open Access)
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Outcome of systemic therapy in patients with advanced rare skin cancers : A retrospective multicenter DeCOG study of 209 patientsIn: European Journal of Cancer (EJC), Jg. 228, 2025, 115750DOI (Open Access)
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Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasisIn: Nature Cell Biology, 2025, in pressDOI (Open Access)
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Presence of brain metastasis differentially impacts long-term survival after first-line therapy in melanoma depending on BRAF mutation statusIn: Frontiers in Immunology, Jg. 16, 2025, 1536642DOI, Online Volltext (Open Access)
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Pyoderma gangraenosum : Pathogenese, Diagnostik und TherapieIn: Die Dermatologie, Jg. 76, 2025, Nr. 7, S. 449 – 458
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Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II ActivityIn: Cancer Research, Jg. 85, 2025, Nr. 5, S. 942 – 955DOI (Open Access)
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Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanomaIn: British Journal of Dermatology: BJD, Jg. 192, 2025, Nr. 3, S. 481 – 491
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The molecular blueprint of targeted radionuclide therapyIn: Nature Reviews Clinical Oncology, Jg. 22, 2025, Nr. 11, S. 869 – 894
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Topical ruxolitinib for treatment-induced vitiligo in a patient with metastatic melanomaIn: JAAD Case Reports, Jg. 55, 2025, S. 123 – 125DOI (Open Access)
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Case report: : Durable complete response of a mucosal melanoma of the rectum after neoadjuvant immunotherapy with ipilimumab plus nivolumabIn: Frontiers in Immunology, Jg. 15, 2024, 1369190DOI, Online Volltext (Open Access)
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Comparison of visual diagnostic accuracy of dermatologists practicing in Germany in patients with light skin and skin of colorIn: Scientific Reports, Jg. 14, 2024, Nr. 1, 8740DOI, Online Volltext (Open Access)
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Cranioencephalic functional lymphoid units in glioblastomaIn: Nature Medicine, Jg. 30, 2024, Nr. 10, S. 2947 – 2956DOI (Open Access)
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De novo and salvage purine synthesis pathways across tissues and tumorsIn: Cell, Jg. 187, 2024, Nr. 14, S. 3602 – 3618.e20
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Diätetische Ansätze in der TumortherapieIn: TumorDiagnostik & Therapie, Jg. 45, 2024, Nr. 3, S. 186 – 194
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Early versus late response to PD-1-based immunotherapy in metastatic melanomaIn: European Journal of Cancer (EJC), Jg. 210, 2024, 114295DOI (Open Access)
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Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activationIn: Nature Cancer, Jg. 5, 2024, Nr. 3, S. 433 – 447DOI, Online Volltext (Open Access)
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Multilokuläres Pyoderma gangraenosum durch Levamisol-gestrecktes KokainIn: Die Dermatologie, Jg. 75, 2024, Nr. 8, S. 640
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Pathogenic mitochondrial DNA mutations inhibit melanoma metastasisIn: Science Advances, Jg. 10, 2024, Nr. 44, eadk8801DOI (Open Access)
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Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesisIn: Science, Jg. 386, 2024, Nr. 6722, eado6836
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Short-term post-fast refeeding enhances intestinal stemness via polyaminesIn: Nature, Jg. 633, 2024, Nr. 8031, S. 895 – 904DOI, Online Volltext (Open Access)
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The Interplay between Metabolic Adaptations and Diet in Cancer ImmunotherapyIn: Clinical Cancer Research, Jg. 30, 2024, Nr. 15, S. 3117 – 3127
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Advancements in melanoma cancer metastasis modelsIn: Pigment Cell and Melanoma Research, Jg. 36, 2023, Nr. 2, S. 206 – 223DOI (Open Access)
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Characterisation and outcome of RAC1 mutated melanomaIn: European Journal of Cancer (EJC), Jg. 183, 2023, S. 1 – 10
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Combined immunotherapy with ipilimumab plus nivolumab in metastatic PD-1/PD-L1-refractory Merkel cell carcinoma : a case reportIn: International Journal of Dermatology, Jg. 63, 2023, Nr. 2, S. e69 – e71
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Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma ADOREG/TRIM : Analysis of the DeCOG prospective multicenter cohort studyIn: eBioMedicine, Jg. 96, 2023, 104774DOI (Open Access)
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Diätetische Ansätze in der TumortherapieIn: Aktuelle Dermatologie, Jg. 49, 2023, Nr. 12, S. 556 – 564
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Ekzeme der Wundumgebung : Genese, Diagnostik und TherapieIn: Zeitschrift für Gerontologie und Geriatrie, Jg. 56, 2023, Nr. 6, S. 505 – 515
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Leptin receptor⁺ cells promote bone marrow innervation and regeneration by synthesizing nerve growth factorIn: Nature Cell Biology, Jg. 25, 2023, Nr. 12, S. 1746 – 1757DOI (Open Access)
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Multi-omics approaches to study platelet mechanismsIn: Current Opinion in Chemical Biology, Jg. 73, 2023, 102253DOI (Open Access)
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Multispectral optoacoustic tomography to differentiate between lymph node metastases and coronavirus-19 vaccine-associated lymphadenopathyIn: Journal of the European Academy of Dermatology and Venereology, Jg. 37, 2023, Nr. 5: Special issue on melanoma: Immune check point and BRAF‐MEK inhibitors in melanoma, S. 907 – 913DOI (Open Access)
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Prognostic factors in the primary care of patients with Merkel cell carcinoma : A monocentric cohort study of 108 patients from a tertiary referral centreIn: JEADV Clinical Practice, Jg. 2, 2023, Nr. 4, S. 810 – 818DOI, Online Volltext (Open Access)
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Compartmentalized metabolism supports midgestation mammalian developmentIn: Nature, Jg. 604, 2022, Nr. 7905, S. 349 – 353DOI (Open Access)
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Emerging metabolomic tools to study cancer metastasisIn: Trends in Cancer, Jg. 8, 2022, Nr. 12, S. 988 – 1001DOI (Open Access)
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In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumorsIn: Science Advances, Jg. 8, 2022, Nr. 35, eabn9550DOI (Open Access)
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Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone massIn: eLife, Jg. 8, 2022, S. e42274DOI (Open Access)
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Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cellsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 119, 2022, Nr. 6, e2120617119DOI (Open Access)
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Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathwayIn: Nature Communications, Jg. 13, 2022, Nr. 1, 2698DOI (Open Access)
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A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesisIn: Nature, Jg. 591, 2021, Nr. 7850, S. 438 – 444DOI, Online Volltext (Open Access)
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Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologiesIn: Med, Jg. 2, 2021, Nr. 4, S. 395 – 410.e4DOI (Open Access)
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Metabolomic profiling of rare cell populations isolated by flow cytometry from tissuesIn: eLife, Jg. 10, 2021, e61980DOI (Open Access)
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Redox regulation in cancer cells during metastasisIn: Cancer Discovery, Jg. 11, 2021, Nr. 11, S. 2682 – 2692DOI (Open Access)
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Stable isotope tracing to assess tumor metabolism in vivoIn: Nature Protocols, Jg. 16, 2021, Nr. 11, S. 5123 – 5145DOI, Online Volltext (Open Access)
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The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectinIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 118, 2021, Nr. 25, e2026176118DOI (Open Access)
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U-RT1 : A new model for Richter transformationIn: Neoplasia: An International Journal for Oncology Research, Jg. 23, 2021, Nr. 1, S. 140 – 148DOI (Open Access)
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Lymph protects metastasizing melanoma cells from ferroptosisIn: Nature, Jg. 585, 2020, Nr. 7823, S. 113 – 118DOI, Online Volltext (Open Access)
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Metabolic heterogeneity confers differences in melanoma metastatic potentialIn: Nature, Jg. 577, 2020, Nr. 7788, S. 115 – 120DOI, Online Volltext (Open Access)
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Mitochondrial DNA Haplotypes as Genetic Modifiers of CancerIn: Trends in Cancer, Jg. 6, 2020, Nr. 12, S. 1044 – 1058
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Loss of EZH2 reprograms BCAA metabolism to drive leukemic transformationIn: Cancer Discovery, Jg. 9, 2019, Nr. 9, S. 1228 – 1247DOI, Online Volltext (Open Access)
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TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 SignalingIn: Cell Reports, Jg. 28, 2019, Nr. 9, S. 2293 – 2305.e9DOI (Open Access)
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9-cis-Retinoic acid induces a distinct regulatory dendritic cell phenotype that modulates murine delayed-type allergyIn: Contact Dermatitis, Jg. 78, 2018, Nr. 1, S. 41 – 54
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NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALSIn: The EMBO Journal, Jg. 37, 2018, Nr. 16, e98697DOI (Open Access)
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The H3K4 methyltransferase setd1b is essential for hematopoietic stem and progenitor cell homeostasis in miceIn: eLife, Jg. 7, 2018, e27157DOI (Open Access)
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Analysis of gender-specific Differences in Response to First-line Treatment with Immunotherapy or targeted Therapy in Melanoma Patients with metastatic Stage IV Melanoma : An ADO/DeCOG Study of 2032 Patients from the prospective, multicenter Skin Cancer Registry ADOREGIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 22, 2024, Nr. Suppl. 4, S. 16 – 17
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PD-L1 Expression in Lymph Node Metastases as a Predictor of adjuvant Immunotherapy Success in Stage III Melanoma Patients: An Analysis of the prospective ADOREG Study TRIM-ADJUVANTIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 22, 2024, Nr. Suppl. 4, S. 15 – 16
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The PD-L1 Expression predicts the Outcome of anti-PD-1/PD-L1-based Immune Checkpoint Therapy in Patients with metastatic Merkel Cell CarcinomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 22, 2024, Nr. Suppl. 4, S. 17 – 18
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Die PD-L1-Expression im Tumor prognostiziert je nach Art des untersuchten Gewebes das Outcome einer Anti-PD-1-basierten Immuntherapie bei metastasiertem Melanom
33. Deutscher Hautkrebskongress (ADO-Jahrestagung) ; 06.–09. September 2023, Hamburg, Germany,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 21, 2023, Nr. S4, Special Issue: Abstractband anlässlich des 33. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 06.–09. September 2023 Hamburg, S. 27 – 28DOI (Open Access) -
Predictors of long-term survival of Stage IV melanoma patients: a multicenter DeCOG study on 395 patients from the prospective skin cancer registry ADOREG
52. Tagung der Deutschen Dermatologischen Gesellschaft, Vereinigung Deutschsprachiger Dermatologen e. V., 26.-29.04.2023, Berlin,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 21, 2023, Nr. S1, Special Issue: Abstractband anlässlich der 52. Tagung der Deutschen Dermatologischen Gesellschaft, Vereinigung Deutschsprachiger Dermatologen e. V. 26. bis 29. April 2023, Berlin, S. 9 – 27DOI (Open Access) -
Predictors of long-term survival of stage IV melanoma patients : a multicenter DeCOG study on 539 patients from the prospective skin cancer registry ADOREG
32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG). Hoboken: Wiley-Blackwell - STM, Jg. 20, 2022, Nr. S3, S. 16 – 17 -
Redirecting resistance evolution in BRAFV600 melanoma by inhibition of the peroxiredoxin-thioredoxin system2025DOI (Open Access)
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Tumor PD-L1 predicts the outcome of PD-1-based immunotherapy in metastatic melanoma depending on the type of tissue examined
ESMO Congress 2023 ; 20 - 24 October 2023, Madrid, Spain,In: Annals of Oncology. Amsterdam: Elsevier, Jg. 34, 2023, Nr. Supplement 2: Abstract Book of the ESMO Congress 2023, 20 - 24 October 2023, S. S695