Personensuche
Personensuche
Es wurde 1 Person gefunden.
Klinik für Kinderheilkunde, AG Experimentelle perinatale Neurowissenschaften
Anschrift
Essen
E-Mail
Funktionen
-
Mitglied, Zentrum für Medizinische Biotechnologie
Aktuelle Veranstaltungen
Keine aktuellen Veranstaltungen.
Vergangene Veranstaltungen (max. 10)
-
WiSe 2024
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
A Novel Model for Simultaneous Evaluation of Hyperoxia-Mediated Brain and Lung Injury in Neonatal RatsIn: Cells, Jg. 14, 2025, Nr. 6, S. 443DOI (Open Access)
-
Extracellular vesicles lay the ground for neuronal plasticity by restoring mitochondrial function, cell metabolism and immune balanceIn: Journal of Cerebral Blood Flow and Metabolism (JCBFM), 2025, in press
-
Gut microbiota deficiency reduces neutrophil activation and is protective after ischemic strokeIn: Journal of Neuroinflammation, Jg. 22, 2025, Nr. 1, 137DOI (Open Access)
-
Hypoxic-ischemic brain injury in neonatal mice sequentially recruits neutrophils with dichotomous phenotype and functionIn: Nature Communications, Jg. 16, 2025, Nr. 1, 9696DOI (Open Access)
-
Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injuryIn: Journal of Neuroinflammation, Jg. 22, 2025, Nr. 1, 57DOI (Open Access)
-
Prolonged Exposure to Neonatal Hyperoxia Impairs Neuronal and Oligodendrocyte Maturation Associated with Long-Lasting Neuroinflammatory Responses in Juvenile MiceIn: Cells, Jg. 14, 2025, Nr. 15, 1141DOI, Online Volltext (Open Access)
-
A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, “Therapeutic advances with native and engineered human extracellular vesicles”In: Cytotherapy, Jg. 25, 2023, Nr. 8, S. 810 – 814
-
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injuryIn: Inflammation and Regeneration, Jg. 43, 2023, Nr. 1, 24DOI, Online Volltext (Open Access)
-
Hypothermia combined with extracellular vesicles from clonally expanded immortalized mesenchymal stromal cells improves neurodevelopmental impairment in neonatal hypoxic-ischemic brain injuryIn: Journal of Neuroinflammation, Jg. 20, 2023, Nr. 1, 280DOI, Online Volltext (Open Access)
-
Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infectionsIn: PLoS Pathogens, Jg. 19, 2023, Nr. 11, e1011837DOI (Open Access)
-
Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain AxisIn: Oxidative Medicine and Cellular Longevity, 2022, 5784146DOI (Open Access)
-
Peripheral immune cells and perinatal brain injury : A double-edged sword?In: Pediatric Research, Jg. 91, 2022, Nr. 2, S. 392 – 403DOI (Open Access)
-
Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged MiceIn: Stroke, Jg. 53, 2022, Nr. 1, S. E14 – E18DOI (Open Access)
-
Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain InjuryIn: Stroke, Jg. 53, 2022, Nr. 2, S. 381 – 390DOI (Open Access)
-
Hypothermia modulates myeloid cell polarization in neonatal hypoxic–ischemic brain injuryIn: Journal of Neuroinflammation, Jg. 18, 2021, Nr. 1, 266DOI, Online Volltext (Open Access)
-
Neutrophil dynamics, plasticity and function in acute neurodegeneration following neonatal hypoxia-ischemiaIn: Brain, Behavior and Immunity, Jg. 92, 2021, S. 234 – 244DOI (Open Access)
-
Involvement of CXCL1/CXCR2 During Microglia Activation Following Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal RatsIn: Frontiers in Neurology, Jg. 11, 2020, S. 540878DOI, Online Volltext (Open Access)
-
Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Neuroinflammation, Promote Neural Cell Proliferation and Improve Oligodendrocyte Maturation in Neonatal Hypoxic-Ischemic Brain InjuryIn: Frontiers in Cellular Neuroscience, Jg. 14, 2020, S. 601176DOI, Online Volltext (Open Access)
-
Repetitive Erythropoietin Treatment Improves Long-Term Neurocognitive Outcome by Attenuating Hyperoxia-Induced Hypomyelination in the Developing BrainIn: Frontiers in Neurology, Jg. 11, 2020, S. 804DOI, Online Volltext (Open Access)
-
White Matter Brain Development after Exposure to Circulating Cell-Free Hemoglobin and Hyperoxia in a Rat Pup ModelIn: Developmental Neuroscience, Jg. 41, 2020, Nr. 3-4, S. 234 – 246DOI (Open Access)
-
Adverse neuropsychiatric development following perinatal brain injury : from a preclinical perspectiveIn: Pediatric Research, Jg. 85, 2019, Nr. 2, S. 198 – 215
-
Detrimental Impact of Energy Drink Compounds on Developing Oligodendrocytes and NeuronsIn: Cells, Jg. 8, 2019, Nr. 11, S. 1381DOI, Online Volltext (Open Access)
-
Early pro-inflammatory microglia activation after inflammation-sensitized hypoxic-ischemic brain injury in neonatal ratsIn: Frontiers in Cellular Neuroscience, Jg. 13, 2019, S. 237DOI (Open Access)
-
Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain InjuryIn: Molecular Neurobiology, Jg. 56, 2019, Nr. 1, S. 567 – 582
-
Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injuryIn: Brain, Behavior and Immunity, Jg. 70, 2018, S. 118 – 130DOI (Open Access)
-
Peripheral T cell depletion by FTY720 exacerbates hypoxic-ischemic brain injury in neonatal miceIn: Frontiers in Immunology, Jg. 9, 2018, S. 1696DOI (Open Access)
-
Protection of oligodendrocytes through neuronal overexpression of the small GTPase ras in hyperoxia-induced neonatal brain injuryIn: Frontiers in Neurology, Jg. 9, 2018, S. 175DOI, Online Volltext (Open Access)
-
Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitisIn: Journal of Autoimmunity, Jg. 76, 2017, S. 108 – 114
-
Effects of Poly(ADP-Ribose) Polymerase-1 Inhibition in a Neonatal Rodent Model of Hypoxic-Ischemic InjuryIn: BioMed Research International, 2017, 2924848DOI (Open Access)
-
Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injuryIn: Brain, Behavior and Immunity, Jg. 60, 2017, S. 220 – 232DOI (Open Access)
-
Sildenafil Enhances Quantity of Immature Neurons and Promotes Functional Recovery in the Developing Ischemic Mouse BrainIn: Developmental Neuroscience, Jg. 39, 2017, Nr. 1-4, S. 287 – 297
-
Endogenous hypothermic response to hypoxia reduces brain injury : Implications for modeling hypoxic-ischemic encephalopathy and therapeutic hypothermia in neonatal miceIn: Experimental Neurology, Jg. 283, Part A, 2016, S. 264 – 275DOI (Open Access)
-
Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain InjuryIn: Oxidative Medicine and Cellular Longevity, 2016, S. 9247493DOI (Open Access)
-
Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxiaIn: Brain, Behavior and Immunity, Jg. 52, 2016, S. 106 – 119DOI (Open Access)
-
Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic ImmunosuppressionIn: Stem Cells Translational Medicine, Jg. 4, 2015, Nr. 10, S. 1131 – 1143DOI (Open Access)
-
Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic MiceIn: Stroke, Jg. 46, 2015, Nr. 10, S. 2916 – 2925DOI (Open Access)
-
Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammationIn: Acta Neuropathologica, Jg. 130, 2015, Nr. 6, S. 799 – 814DOI (Open Access)
-
Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental strokeIn: Acta Neuropathologica, Jg. 129, 2015, Nr. 2, S. 259 – 277
-
Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responsesIn: Neurobiology of Disease, Jg. 62, 2014, S. 456 – 468
-
Inhibition of Acetylcholinesterase Modulates NMDA Receptor Antagonist Mediated Alterations in the Developing BrainIn: International Journal of Molecular Sciences (IJMS), Jg. 15, 2014, Nr. 3, S. 3784 – 3798DOI (Open Access)
-
Modulation of Dendritic Cell Immunobiology via Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) ReductaseIn: PLoS ONE, Jg. 9, 2014, Nr. 7, S. e100871DOI (Open Access)
-
Neuroprotection by blocking CXCR2 after cerebral ischemia in hypercholesterolemic miceIn: Journal of Neuroimmunology, Jg. 275, 2014, Nr. 1-2, S. 152 – 153
-
Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral VesselsIn: JoVE, 2013, Nr. 71, S. e4374DOI, Online Volltext (Open Access)
-
Parallelized TCSPC for dynamic intravital fluorescence lifetime imaging : quantifying neuronal dysfunction in neuroinflammationIn: PLoS ONE, Jg. 8, 2013, Nr. 4, S. e60100DOI (Open Access)
-
The role of CD8+T cells and their local interaction with CD4+T cells in myelin oligodendrocyte glycoprotein35-55-induced experimental autoimmune encephalomyelitisIn: The Journal of Immunology (JI), Jg. 191, 2013, Nr. 10, S. 4960 – 4968
-
Acute peripheral and CNS immune responses in hypercholesterolemic mice after mild brain ischemiaIn: Journal of Neuroimmunology, Jg. 253, 2012, Nr. 1-2, S. 99
-
Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actionsIn: Neurobiology of Disease, Jg. 45, 2012, Nr. 3, S. 1077 – 1085
-
Intravascular perfusion of carbon black ink allows reliable visualization of cerebral vessels in miceIn: European Journal of Neurology, Jg. 19, 2012, Nr. Suppl. 1, S. 185
-
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesisIn: Brain: A Journal of Neurology, Jg. 135, 2012, Nr. 11, S. 3282 – 3297
-
Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone : Therapeutic potential against ischemic stroke after intrastriatal and systemic transplantationIn: Stem Cells, Jg. 30, 2012, Nr. 6, S. 1297 – 1310
-
Visualization of macroscopic cerebral vessel anatomy—A new and reliable technique in miceIn: Journal of Neuroscience Methods, Jg. 204, 2012, Nr. 2, S. 249 – 253
-
In vivo imaging of lymphocytes in the CNS reveals different behaviour of naïve T cells in health and autoimmunityIn: Journal of Neuroinflammation, Jg. 8, 2011, S. 131DOI (Open Access)
-
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous systemIn: Nature Medicine, Jg. 15, 2009, Nr. 7, S. 788 – 793
-
Geranylgeranylation but not GTP loading determines rho migratory function in T cellsIn: The Journal of Immunology, Jg. 179, 2007, Nr. 9, S. 6024 – 6032
-
Clonal immortalized mesenchymal stromal cells : An ideal cell source for a reproducible and standardized production of therapeutic extracellular vesiclesIn: Cytotherapy. London; Oxford; Basingstoke; London: International Society for Cellular Therapy, Jg. 26, 2024, Nr. 6, S. S83
-
Regulatory T cells contribute to sexual dimorphism in neonatal hypoxic-ischemic brain injury
4th Congress of Joint European Neonatal Societies: Brain, Development and Imaging; 14–18 September 2021; Virtual, Online,In: Pediatric Research. Berlin: Springer Nature, Jg. 90, 2021, Nr. Suppl. 1, S. 3DOI (Open Access) -
Catch me if you can! : Novel immune escape mechanisms in melanoma metastases of the brain
45th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF) ; March 7‐10, 2018, Zürich,In: Experimental Dermatology. Hoboken: Wiley, Jg. 27, 2018, Nr. 3, S. e15DOI (Open Access) -
Exosomes reduce brain injury in a rodent stroke model via immunomodulatory actions and stimulation of post-ischemic neuroregeneration
Joint Congress of European Neurology 31 May–3 June 2014 Istanbul, Turkey,In: Journal of Neurology. Berlin; Leipzig: Springer, Jg. 261, 2014, Nr. Suppl. 1, S. 70 -
Exosomes reduce brain injury in a rodent stroke model via immunomodulatory actions and stimulation of post-ischemic neuroregeneration
Joint Congress of European Neurology, Istanbul, Turkey, May 2014,In: European Journal of Neurology. Hoboken: Wiley, Jg. 21, 2014, Nr. Suppl. 1, S. 97 -
Activation of kinin receptor B1 limits encephalitogenic T-lymphocyte recruitment to the central nervous systemIn: Multiple Sclerosis Journal. London: Sage, Jg. 15, 2009, Nr. 9, Supplement, S. S75
-
Neuroinflammation in der ischämischen Hirnschädigung : Chancen und Herausforderungen in der prä-klinischen Evaluation protektiver TherapieansätzeDuisburg ; Essen, 2018
-
CLONAL IMMORTALIZED MESENCHYMAL STROMAL CELLS APPEAR AS AN IDEAL CELL SOURCE FOR THE PRODUCTION OF THERAPEUTIC EXTRACELLULAR VESICLES
28th Annual ISCT Meeting; 4-7 May 2022; San Francisco, USA,In: Cytotherapy. London; Oxford; Basingstoke; London: International Society for Cellular Therapy, Jg. 24, 2022, Nr. 5, Supplement, S. S87