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Fakultät für Chemie
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S07 S05 C46
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Gruppe der Professorinnen und Professoren, Fakultätsrat
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---, SFB 1093
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Universitätsprofessor/in, Organische Chemie
Aktuelle Veranstaltungen
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2024 SS
- Chemie-Vertiefung (Organische Chemie)
- Anleitung zum selbständigen wissenschaftlichen Arbeiten
- Grundpraktikum Organische Chemie
- Ausgewählte Kapitel der Organischen Chemie
- Organische Chemie (OC-P)
- Praktikum Organische Chemie
- Seminar zum Praktikum Organische Chemie
- Seminar zum Fortgeschrittenenpraktikum Organische Chemie
- ZIA71027/ZIA40169 Klausur Organische Chemie
- Disputation Taghuo
- Disputation Le
Vergangene Veranstaltungen (max. 10)
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2023 WS
- Organische Chemie (OC-P)
- Anleitung zum selbständigen wissenschaftlichen Arbeiten
- Grundpraktikum Organische Chemie
- Integriertes Synthesepraktikum
- Ausgewählte Kapitel der Organischen Chemie
- ZIA71027/ZIA40169 Klausur Organische Chemie
- Kaffeerunde GDCh
- Organische Chemie III (Organisch-Chemische Synthese)
- Klausureinsicht zur OC III-Klausur
- Organische Chemie III (Organisch-Chemische Synthese)
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Günter Wulff (1935 –2023) : Father of Molecular ImprintingIn: Angewandte Chemie International Edition (2024) e202402244 in pressOnline Volltext: dx.doi.org/ (Open Access)
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Characterization of Molecular Tweezer Binding on α-Synuclein with Native Top-Down Mass Spectrometry and Ion Mobility-Mass Spectrometry Reveals a Mechanism for Aggregation InhibitionIn: Journal of the American Society for Mass Spectrometry (JASMS) Jg. 34 (2023) Nr. 12, S. 2739 - 2747Online Volltext: dx.doi.org/
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Design and Synthesis of Artificial Nucleobases for Sequence-Selective DNA Recognition within the Major GrooveIn: Chemistry: An Asian Journal Jg. 18 (2023) Nr. 19, e202300637Online Volltext: dx.doi.org/ (Open Access)
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Modulation of Aβ42 Aggregation Kinetics and Pathway by Low-Molecular-Weight InhibitorsIn: ChemBioChem Jg. 24 (2023) Nr. 7, e202200760Online Volltext: dx.doi.org/ (Open Access)
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Molecular Tweezers : Supramolecular Hosts with Broad-Spectrum Biological ApplicationsIn: Pharmacological Reviews Jg. 75 (2023) Nr. 2, S. 263 - 308Online Volltext: dx.doi.org/
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Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with MicrotubulesIn: Journal of the American Chemical Society: JACS Jg. 145 (2023) Nr. 28, S. 15251 - 15264Online Volltext: dx.doi.org/
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Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules Jg. 24 (2023) Nr. 8, S. 3666 - 3679Online Volltext: dx.doi.org/
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Advanced Molecular Tweezers with Lipid Anchors against SARS-CoV-2 and Other Respiratory VirusesIn: JACS Au Jg. 2 (2022) Nr. 9, S. 2187 - 2202Online Volltext: dx.doi.org/ (Open Access)
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Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host ClassesIn: ChemBioChem Jg. 23 (2022) Nr. 2, e202100502Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers - a new class of potent broad-spectrum antivirals against enveloped virusesIn: Chemical Communications: ChemComm Jg. 58 (2022) Nr. 18, S. 2954 - 2966Online Volltext: dx.doi.org/ (Open Access)
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Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules Jg. 23 (2022) Nr. 11, S. 4504 - 4518Online Volltext: dx.doi.org/
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A tribute to Carsten SchmuckIn: Beilstein Journal of Organic Chemistry Jg. 17 (2021) S. 2795 - 2798Online Volltext: dx.doi.org/ (Open Access)
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Correction to : The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic miceIn: Alzheimer's Research & Therapy Jg. 13 (2021) Nr. 1, S. 88Online Volltext: dx.doi.org/ (Open Access)
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Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezersIn: Cell Chemical Biology Jg. 28 (2021) Nr. 9, S. 1310 - 1320.e5Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Lysine-selective molecular tweezers are cell penetrant and concentrate in lysosomesIn: Communications Biology Jg. 4 (2021) Nr. 1, 1076Online Volltext: dx.doi.org/ (Open Access)
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New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 1, S. 115 - 127Online Volltext: dx.doi.org/ (Open Access)
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Prospects of ultraviolet resonance Raman spectroscopy in supramolecular chemistry on proteinsIn: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Jg. 254 (2021) S. 119622Online Volltext: dx.doi.org/ (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505Online Volltext: dx.doi.org/ (Open Access)
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Supramolecular Enhancement of a Natural 14-3-3 Protein LigandIn: Journal of the American Chemical Society: JACS Jg. 143 (2021) Nr. 34, S. 13495 - 13500Online Volltext: dx.doi.org/
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The Molecular Tweezer CLR01 Inhibits Antibody-Resistant Cell-to-Cell Spread of Human CytomegalovirusIn: Viruses Jg. 13 (2021) Nr. 9, 1685Online Volltext: dx.doi.org/ (Open Access)
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The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic miceIn: Alzheimer's Research & Therapy Jg. 13 (2021) Nr. 1, S. 6Online Volltext: dx.doi.org/ (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719Online Volltext: dx.doi.org/ (Open Access)
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Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Jg. 10 (2020) Nr. 48, S. 28711 - 28719Online Volltext: dx.doi.org/ (Open Access)
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Artificial Signal TransductionIn: ChemistryOpen Jg. 9 (2020) Nr. 6, S. 667 - 682Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s diseaseIn: Nature Communications Jg. 11 (2020) Nr. 1, S. 4885Online Volltext: dx.doi.org/ (Open Access)
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Chirality sensing of terpenes, steroids, amino acids, peptides and drugs with acyclic cucurbit[: N] urils and molecular tweezersIn: Chemical Communications: ChemComm Jg. 56 (2020) Nr. 34, S. 4652 - 4655Online Volltext: dx.doi.org/ (Open Access)
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Different Inhibitors of Aβ42-Induced Toxicity Have Distinct Metal-Ion DependencyIn: ACS Chemical Neuroscience Jg. 11 (2020) Nr. 15, S. 2243 - 2255Online Volltext: dx.doi.org/ (Open Access)
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Structural rearrangement of amyloid-β upon inhibitor binding suppresses formation of Alzheimer’s disease related oligomersIn: eLife Jg. 9 (2020) S. 59306Online Volltext: dx.doi.org/ (Open Access)
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Supramolecular Mechanism of Viral Envelope Disruption by Molecular TweezersIn: Journal of the American Chemical Society: JACS Jg. 142 (2020) Nr. 40, S. 17024 - 17038Online Volltext: dx.doi.org/ (Open Access)
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The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage DiseaseIn: Molecular Therapy Jg. 28 (2020) Nr. 4, S. 1167 - 1176Online Volltext: dx.doi.org/ (Open Access)
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Bisphosphonate ligand mediated ultrasensitive capacitive protein sensor : complementary match of supramolecular and dynamic chemistryIn: New Journal of Chemistry Jg. 43 (2019) Nr. 2, S. 847 - 852Online Volltext: dx.doi.org/
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Dissociation of the Signaling Protein K-Ras4B from Lipid Membranes Induced by a Molecular TweezerIn: Chemistry - A European Journal Jg. 25 (2019) Nr. 42, S. 9827 - 9833Online Volltext: dx.doi.org/
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Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential InhibitorsIn: ACS Chemical Biology Jg. 14 (2019) Nr. 6, S. 1363 - 1379Online Volltext: dx.doi.org/ (Open Access)
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Molecular lysine tweezers counteract aberrant protein aggregationIn: Frontiers in Chemistry Jg. 7 (2019) 657Online Volltext: dx.doi.org/ (Open Access)
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Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly ModulatorIn: Journal of the American Society for Mass Spectrometry (JASMS) Jg. 30 (2019) Nr. 1, S. 16 - 23Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALSIn: The Journal of Biological Chemistry (JBC) Jg. 294 (2019) Nr. 10, S. 3501 - 3513Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The molecular tweezer CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophyIn: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Jg. 1865 (2019) Nr. 11, S. 165513Online Volltext: dx.doi.org/ (Open Access)
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A Synthetic Methodology Toward Pyrrolo[2,3- b]pyridones for GC Base Pair RecognitionIn: Organic Letters Jg. 20 (2018) Nr. 21, S. 6961 - 6964Online Volltext: dx.doi.org/
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Cell entry of a host-targeting protein of oomycetes requires gp96In: Nature Communications Jg. 9 (2018) Nr. 1, S. 2347Online Volltext: dx.doi.org/ (Open Access)
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Maßgeschneiderte Liganden für Protein-Protein-InteraktionenIn: Biospektrum Jg. 24 (2018) Nr. 4, S. 387 - 389Online Volltext: dx.doi.org/
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Molecular tweezers with additional recognition sitesIn: Chemistry - A European Journal Jg. 24 (2018) Nr. 44, S. 11332 - 11343Online Volltext: dx.doi.org/
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The molecular tweezer CLR01 inhibits Ebola and Zika virus infectionIn: Antiviral Research Jg. 152 (2018) S. 26 - 35Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3In: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 31, S. 8998 - 9002Online Volltext: dx.doi.org/ (Open Access)
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A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-SynucleinIn: Neurotherapeutics Jg. 14 (2017) Nr. 4, S. 1107 - 1119Online Volltext: dx.doi.org/
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An NMR Method To Pinpoint Supramolecular Ligand Binding to Basic Residues on ProteinsIn: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 46, S. 14758 - 14762Online Volltext: dx.doi.org/
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High-Affinity copolymers inhibit digestive enzymes by surface recognitionIn: Biomacromolecules Jg. 18 (2017) Nr. 6, S. 1772 - 1784Online Volltext: dx.doi.org/
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Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01In: Journal of the American Chemical Society: JACS Jg. 139 (2017) Nr. 16, S. 5640 - 5643Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Inhibition of Mutant αB Crystallin‐Induced Protein Aggregation by a Molecular TweezerIn: Journal of the American Heart Association Jg. 6 (2017) S. e006182Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers inhibit PARP-1 by a new mechanismIn: European Journal of Organic Chemistry (2017) Nr. 16, S. 2223 - 2229Online Volltext: dx.doi.org/
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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein InterfaceIn: Journal of the American Chemical Society: JACS Jg. 139 (2017) Nr. 45, S. 16256 - 16263Online Volltext: dx.doi.org/ (Open Access)
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Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cellsIn: OncoTarget Jg. 7 (2016) S. 61890 - 61904Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers for lysine and arginine : powerful inhibitors of pathologic protein aggregationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 76, S. 11318 - 11334Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers target a protein-protein interface and thereby modulate complex formationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 98, S. 14141 - 14144Online Volltext: dx.doi.org/ (Open Access)
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Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish EmbryosIn: Environmental Health Perspectives Jg. 124 (2016) Nr. 11, S. 1766 - 1775Online Volltext: dx.doi.org/ (Open Access)
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Protein Camouflage : Supramolecular Anion Recognition by UbiquitinIn: ChemBioChem Jg. 17 (2016) Nr. 8, S. 774 - 783Online Volltext: dx.doi.org/
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Reducing synuclein accumulation improves neuronal survival after spinal cord injuryIn: Experimental Neurology Jg. 278 (2016) S. 105 - 115Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A molecular tweezer antagonizes seminal amyloids and HIV infectionIn: eLife Jg. 4 (2015) Nr. 8, S. e05397Online Volltext: dx.doi.org/ (Open Access)
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Amyloid β-Protein Assembly : The Effect of Molecular Tweezers CLR01 and CLR03In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 119 (2015) Nr. 14, S. 4831 - 4841Online Volltext: dx.doi.org/ (Open Access)
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Hybridization of an Aβ-specific antibody fragment with aminopyrazole-based β-sheet ligands displays striking enhancement of target affinityIn: Organic and Biomolecular Chemistry Jg. 13 (2015) Nr. 10, S. 2974 - 2979Online Volltext: dx.doi.org/ (Open Access)
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Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanismIn: ACS Chemical Biology Jg. 10 (2015) Nr. 6, S. 1555 - 1569Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The lys-specific molecular tweezer, CLR01, modulates aggregation of the mutant p53 DNA binding domain and inhibits its toxicityIn: Biochemistry Jg. 54 (2015) Nr. 24, S. 3729 - 3738Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Toxicity inhibitors protect lipid membranes from disruption by Aβ42In: ACS Chemical Neuroscience Jg. 6 (2015) Nr. 11, S. 1860 - 1869Online Volltext: dx.doi.org/
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Affinity polymers tailored for the protein A binding site of immunoglobulin G proteinsIn: Chemistry - A European Journal Jg. 20 (2014) Nr. 36, S. 11479 - 11487Online Volltext: dx.doi.org/
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Affinity polymers tailored for the protein A binding site of immunoglobulin G proteinsIn: Chemistry - A European Journal Jg. 20 (2014) Nr. 36, S. 11479 - 11487
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Counteracting Semen-mediated Enhancement of HIV Infection and Enveloped Virus Infection by a Lysine-specific Molecular TweezerIn: AIDS Research and Human Retroviruses Jg. 30 (2014) Nr. S1, S. A263Online Volltext: dx.doi.org/
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Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular TweezerIn: The Journal of Biological Chemistry (JBC) Jg. 289 (2014) Nr. 5, S. 10727 - 10737Online Volltext: dx.doi.org/
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Molecular Tweezers Targeting Transthyretin AmyloidosisIn: Neurotherapeutics Jg. 11 (2014) Nr. 2, S. 450 - 461Online Volltext: dx.doi.org/ (Open Access)
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Safety and pharmacological characterization of the molecular tweezer CLR01 – a broad-spectrum inhibitor of amyloid proteins’ toxicityIn: BMC Pharmacology and Toxicology Jg. 15 (2014) S. 23Online Volltext: dx.doi.org/ (Open Access)
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Aromatic interactions by molecular tweezers and clips in chemical and biological systemsIn: Accounts of Chemical Research Jg. 46 (2013) Nr. 4, S. 967 - 978Online Volltext: dx.doi.org/
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Ditopic arginine-aspartate binders recognize RGD loopsIn: European Journal of Organic Chemistry (2013) Nr. 6, S. 1080 - 1092Online Volltext: dx.doi.org/
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Linker effects on amino acid and peptide recognition by molecular tweezersIn: European Journal of Organic Chemistry (2013) Nr. 34, S. 7705 - 7714Online Volltext: dx.doi.org/
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Molecular Tweezers with Varying Anions : A Comparative StudyIn: The Journal of Organic Chemistry Jg. 78 (2013) Nr. 13, S. 6721 - 6734Online Volltext: dx.doi.org/
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Molecular tweezers modulate 14-3-3 protein–protein interactionsIn: Nature Chemistry Jg. 5 (2013) Nr. 3, S. 234 - 239Online Volltext: dx.doi.org/
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Transport of supramolecular drugs across the cell membrane by calcium phosphate nanoparticlesIn: Materials Science and Engineering Technology Jg. 44 (2013) Nr. 2-3, S. 176 - 182Online Volltext: dx.doi.org/
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Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricusIn: Extremophiles Jg. 17 (2013) Nr. 2, S. 205 - 216Online Volltext: dx.doi.org/
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A Novel "Molecular Tweezer" Inhibitor of α-Synuclein Neurotoxicity in Vitro and in VivoIn: Neurotherapeutics Jg. 9 (2012) Nr. 2, S. 464 - 476Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Artificial signal transduction with primary and secondary messengersIn: Chemistry - A European Journal Jg. 18 (2012) Nr. 42, S. 13412 - 13417Online Volltext: dx.doi.org/
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Comparison of Three Amyloid Assembly Inhibitors : The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01In: ACS Chemical Neuroscience Jg. 3 (2012) Nr. 6, S. 451 - 458Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Dimeric calixarenes : A new family of major-groove bindersIn: Chemistry - A European Journal Jg. 18 (2012) Nr. 12, S. 3589 - 3597Online Volltext: dx.doi.org/
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Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formationIn: The Journal of Biological Chemistry (JBC) Jg. 287 (2012) Nr. 41, S. 34786 - 34800Online Volltext: dx.doi.org/
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Erratum to: A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity In Vitro and In VivoIn: Neurotherapeutics Jg. 9 (2012) Nr. 2, S. 486Online Volltext: dx.doi.org/
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Interactions of calix[n]arenes with nucleic acidsIn: Nature Communications Jg. 7 (2012) Nr. 3, S. 409 - 417
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Isolated β-turn model systems investigated by combined IR/UV spectroscopyIn: ChemPhysChem Jg. 13 (2012) Nr. 6, S. 1576 - 1582Online Volltext: dx.doi.org/
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Protection of primary neurons and mouse brain from Alzheimer’s pathology by molecular tweezersIn: Brain: A Journal of Neurology Jg. 135 (2012) Nr. 12, S. 3735 - 3748Online Volltext: dx.doi.org/
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Protein recognition : Calixarene connectionIn: Nature Chemistry Jg. 4 (2012) Nr. 7, S. 519 - 520Online Volltext: dx.doi.org/
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A Modular Synthetic Route to Dimeric Calixarenes : A New Family of DNA Major Groove BindersIn: Synthesis: Journal of Synthetic Organic Chemistry (2011) Nr. 8, S. 1193 - 1204Online Volltext: dx.doi.org/
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Artificial synthetic receptors as regulators of protein activityIn: Chemical Communications: ChemComm Jg. 47 (2011) Nr. 19, S. 5376 - 5383Online Volltext: dx.doi.org/
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Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteinsIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 42, S. 16958 - 16969Online Volltext: dx.doi.org/
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Non covalent inclusion of nucleosides and nucleotides in water-soluble molecular clipsIn: Heterocycles Jg. 82 (2011) Nr. 2, S. 1549 - 1566Online Volltext: dx.doi.org/
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Rational Design of ß-Sheet Ligands Against Aß42-Induced ToxicityIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 12, S. 4348 - 4358Online Volltext: dx.doi.org/
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Artificial RGD receptor moleculesIn: Supramolecular Chemistry Jg. 22 (2010) Nr. 11-12, S. 853 - 861Online Volltext: dx.doi.org/
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Combining independent drug classes into superior, synergistically acting hybrid moleculesIn: Angewandte Chemie International Edition Jg. 49 (2010) Nr. 46, S. 8743 - 8746Online Volltext: dx.doi.org/
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Development and evaluation of a fluorescence microplate assay for quantification of heparins and other sulfated carbohydratesIn: Journal of Pharmaceutical and Biomedical Analysis Jg. 52 (2010) Nr. 1, S. 1 - 8Online Volltext: dx.doi.org/
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Effect of molecular clips and tweezers on enzymatic reactions by binding coenzymes and basic amino acidsIn: Pure and Applied Chemistry Jg. 82 (2010) Nr. 4, S. 991 - 999Online Volltext: dx.doi.org/
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Modulation of aggregate size- and shape-distributions of the amyloid-β peptide by a designed β-sheet breakerIn: European Biophysics Journal Jg. 39 (2010) Nr. 3, S. 415 - 422Online Volltext: dx.doi.org/
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RAFT polymers for protein recognitionIn: Beilstein Journal of Organic Chemistry Jg. 6 (2010) S. 66Online Volltext: dx.doi.org/ (Open Access)
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Wie fasst man Biomoleküle richtig an? : Maßgeschneiderte Nanomaterialien zur Beeinflussung biologischer FunktionenIn: Unikate: Berichte aus Forschung und Lehre (2010) Nr. 37: Naturwissenschaften/Medizin : Nano meets Bio, S. 22 - 31Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Investigation of secondary structure e lements by IR/UV double resonance spectroscopy: Analysis of an isolated beta-sheet model system.In: J. Am. Chem. Soc. 130 (2008) S. 4692 - 4698
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Artificial Ditopic RGD ReceptorsIn: Chemistry - A European Journal Jg. 13 (2007) Nr. 24, S. 6864 - 6873Online Volltext: dx.doi.org/
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Artificial protein sensorsIn: Molecular BioSystems Jg. 3 (2007) Nr. 4, S. 241 - 248Online Volltext: dx.doi.org/
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Synthesis and Binding Studies of Alzheimer Ligands on Solid SupportIn: The Journal of Organic Chemistry Jg. 72 (2007) Nr. 10, S. 3614 - 3624Online Volltext: dx.doi.org/
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Arginine- and Lysine-Specific Polymers for Protein Recognition and ImmobilizationIn: Journal of the American Chemical Society: JACS Jg. 128 (2006) Nr. 2, S. 620 - 628Online Volltext: dx.doi.org/
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DNA Recognition with Large Calixarene DimersIn: Angewandte Chemie International Edition Jg. 45 (2006) Nr. 17, S. 2703 - 2706Online Volltext: dx.doi.org/
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Dendrimeric Bisphosphonates for Multivalent Protein Surface BindingIn: Chemistry: An Asian Journal Jg. 1 (2006) Nr. 4, S. 544 - 554Online Volltext: dx.doi.org/
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Entirely artificial signal transduction with adrenaline.In: Journal of Receptors and Signal Transduction Jg. 26 (2006) Nr. 5-6, S. 473 - 485
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Molecular Tweezer and Clip in Aqueous Solution: Unexpected Self-Assembly, Powerful Host-Guest Complex Formation, Quantum Chemical 1H NMR Shift Calculation.In: Journal of the American Chemical Society: JACS Jg. 128 (2006) Nr. 14, S. 4831 - 4841Online Volltext: dx.doi.org/
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Nucleoside sensing.In: Sensors Jg. 6 (2006) Nr. 8, S. 860 - 873Online Volltext: dx.doi.org/ (Open Access)
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Tuning Linear Copolymers into Protein-Specific HostsIn: Angewandte Chemie International Edition Jg. 45 (2006) Nr. 38, S. 6352 - 6355Online Volltext: dx.doi.org/
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A Color Sensor for CatecholaminesIn: Angewandte Chemie International Edition Jg. 44 (2005) Nr. 15, S. 2265 - 2270Online Volltext: dx.doi.org/
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A Molecular Tweezer for Lysine and ArginineIn: Journal of the American Chemical Society: JACS Jg. 127 (2005) Nr. 41, S. 14415 - 14421Online Volltext: dx.doi.org/
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Inclusion of Thiamine Diphosphate and S-Adenosylmethionine at Their Chemically Active SitesIn: The Journal of Organic Chemistry Jg. 70 (2005) Nr. 25, S. 10227 - 10237Online Volltext: dx.doi.org/
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Selective Complexation of N-Alkylpyridinium Salts : Binding of NAD+ in WaterIn: Chemistry - A European Journal Jg. 11 (2005) Nr. 2, S. 477 - 494Online Volltext: dx.doi.org/
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Sequence-selective peptide recognition with designed modules.In: European Journal of Organic Chemistry (2005) Nr. 1, S. 138 - 153
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β-Sheet Ligands in Action : KLVFF Recognition by Aminopyrazole Hybrid Receptors in WaterIn: Journal of the American Chemical Society: JACS Jg. 127 (2005) Nr. 9, S. 3016 - 3025Online Volltext: dx.doi.org/
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Adrenaline Recognition in WaterIn: Chemistry - A European Journal Jg. 10 (2004) Nr. 17, S. 4225 - 4232Online Volltext: dx.doi.org/
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On the role of PIII ligands in the conjugate addition of diorganozinc derivatives to enonesIn: Chemistry - A European Journal Jg. 10 (2004) Nr. 23, S. 6048 - 6057Online Volltext: dx.doi.org/
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Prevention of Alzheimer's Disease-associated Aβ Aggregation by Rationally Designed Nonpeptidic β-Sheet LigandsIn: The Journal of Biological Chemistry (JBC) Jg. 279 (2004) Nr. 46, S. 47497 - 47505Online Volltext: dx.doi.org/
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Relative binding affinities of molecular capsules investigated by ESI-Mass spectrometryIn: Chemistry - A European Journal Jg. 10 (2004) Nr. 17, S. 4233 - 4239Online Volltext: dx.doi.org/
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Capsule-like Assemblies in Polar SolventsIn: The Journal of Organic Chemistry Jg. 68 (2003) Nr. 17, S. 6511 - 6521Online Volltext: dx.doi.org/
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Highly Sensitive Recognition of Substrates of Adrenergic Receptors at the Air/Water InterfaceIn: Angewandte Chemie International Edition Jg. 42 (2003) Nr. 44, S. 5509 - 5513Online Volltext: dx.doi.org/
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Molecular Recognition of Amidines in WaterIn: Organic Letters Jg. 5 (2003) Nr. 10, S. 1641 - 1644Online Volltext: dx.doi.org/
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Asymmetric synthesis with chiral cyclic phosphorus auxiliariesIn: Synthesis: Journal of Synthetic Organic Chemistry (2002) Nr. 18, S. 2633 - 2670Online Volltext: dx.doi.org/
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Modular Building Blocks for Amino Acid Recognition in PeptidesIn: Angewandte Chemie International Edition Jg. 41 (2002) Nr. 10, S. 1751 - 1754Online Volltext: dx.doi.org/
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Selective Complexation of N-Alkylpyridinium Salts : Recognition of NAD+ in WaterIn: Angewandte Chemie International Edition Jg. 41 (2002) Nr. 8, S. 1355 - 1358Online Volltext: dx.doi.org/
-
Self-Assembly of Ball-Shaped Molecular Complexes in WaterIn: The Journal of Organic Chemistry Jg. 67 (2002) Nr. 11, S. 3755 - 3763Online Volltext: dx.doi.org/
-
The First Synthetic Receptor for the RGD Sequence.In: Organic Letters Jg. 4 (2002) Nr. 13, S. 2161 - 2164
-
A New Receptor Molecule for Lysine and Histidine in Water : Strong Binding of Basic Amino Acid Esters by a Macrocyclic HostIn: Organic Letters Jg. 3 (2001) Nr. 11, S. 1597 - 1600Online Volltext: dx.doi.org/
-
Optimization of a synthetic arginine receptor : Systematic tuning of noncovalent interactions.In: The Journal of Organic Chemistry Jg. 66 (2001) Nr. 17, S. 5814 - 5821Online Volltext: dx.doi.org/
-
Randomized, placebo-controlled trial of lazaroid effects on severe acute pancreatitis in ratsIn: Critical Care Medicine Jg. 29 (2001) Nr. 4, S. 861 - 869
-
Towards synthetic adrenaline receptorsIn: Materials Science and Engineering C: Biomimetic and Supramolecular Systems Jg. 18 (2001) Nr. 1-2, S. 147 - 155Online Volltext: dx.doi.org/
-
A Chiral Sensor for Arginine and LysineIn: Organic Letters Jg. 2 (2000) Nr. 5, S. 605 - 608Online Volltext: dx.doi.org/
-
Organic chemistry 1999 : Molecular recognitionIn: Nachrichten aus der Chemie Jg. 48 (2000) Nr. 3, S. 276 - 280
-
Self-Organization of Spheroidal Molecular Assemblies in Polar SolventsIn: Organic Letters Jg. 2 (2000) Nr. 1, S. 29 - 32Online Volltext: dx.doi.org/
-
Self-organized ball-shaped molecular assemblies in waterIn: Journal of Physical Organic Chemistry Jg. 13 (2000) Nr. 10, S. 670 - 673Online Volltext: dx.doi.org/
-
Towards Synthetic Adrenaline ReceptorsIn: Chemistry - A European Journal Jg. 6 (2000) Nr. 1, S. 47 - 53Online Volltext: dx.doi.org/
-
Chelate Complexes with the P=O-Double Bond - A New Concept for Asymmetric SynthesisIn: Phosphorus, Sulfur, and Silicon and the Related Elements Jg. 144 (1999) Nr. 1, S. 161 - 164Online Volltext: dx.doi.org/
-
Chelate complexes with the PO double bond - a new concept for molecular recognitionIn: Journal of Inclusion Phenomena and Macrocyclic Chemistry Jg. 34 (1999) Nr. 2, S. 117 - 129
-
Synthetic Adrenaline Receptors Based on BisphosphonatesIn: Phosphorus, Sulfur, and Silicon and the Related Elements Jg. 144-146 (1999) S. 749 - 752Online Volltext: dx.doi.org/
-
Anomer-Selective Molecular Recognition of Free Amino Sugars with Simple Bisphosphonate Receptor MoleculesIn: Journal of the American Chemical Society: JACS Jg. 120 (1998) Nr. 45, S. 11816 - 11817Online Volltext: dx.doi.org/
-
Toward Synthetic Adrenaline Receptors : Strong, Selective, and Biomimetic Recognition of Biologically Active Amino Alcohols by Bisphosphonate Receptor MoleculesIn: The Journal of Organic Chemistry Jg. 63 (1998) Nr. 2, S. 264 - 272Online Volltext: dx.doi.org/
-
Unexpected and facile bridgehead substitution in 5,6,7,8,9,10-hexahydro-5,9-methanopyrimido[4,5-b]azocin-4(3H)-onesIn: Tetrahedron Jg. 54 (1998) Nr. 33, S. 9507 - 9518Online Volltext: dx.doi.org/
-
Intermolecular stabilization of the b-sheet conformation in dipeptidesIn: Chemical Communications: ChemComm (1996) Nr. 17, S. 2089 - 2090Online Volltext: dx.doi.org/
-
Towards Synthetic Adrenaline Receptors—Strong Binding of Amino Alcohols by BisphosphonatesIn: Angewandte Chemie International Edition Jg. 35 (1996) Nr. 22, S. 2649 - 2651Online Volltext: dx.doi.org/
-
Phosphoranaloge von Aminosäuren IV.1 Synthesen ungewöhnlicher 1-Aminophosphonsäuren über Diels-Alder-Reaktionen von (N-Acyliminomethyl)phosphonsäurediethylesternIn: Synthesis: Journal of Synthetic Organic Chemistry (1990) Nr. 12, S. 1153 - 1156Online Volltext: dx.doi.org/
-
Phosphoranaloge von Aminosäuren II1 : Synthese von α-Aminophosphonsäuren und α-Aminophosphinsäuren, ausgehend von den entsprechenden N-Acylimino-DerivatenIn: Synthesis: Journal of Synthetic Organic Chemistry (1989) Nr. 2, S. 97 - 101Online Volltext: dx.doi.org/
-
Synthese von 1-Aminophosphonsäure-Derivaten über Acyliminophosphonsäure-EsterIn: Synthesis: Journal of Synthetic Organic Chemistry (1986) Nr. 5, S. 372 - 375Online Volltext: dx.doi.org/
-
Plasmonic gold nanoparticles as platform for biomolecules counteracting protein misfolding diseasesIn: CENIDE Nanobiophotonics Symposium 2015 / CENIDE Nanobiophotonics Symposium 2015 ; Essen, Germany, 11.03.2015 (2015)
-
Molecular Tweezers and Clips that Modify Protein FunctionIn: Supramolecular Protein Chemistry: Assembly, Architecture and Application / Crowley, Peter B. (Hrsg.) 2021, S. 161 - 198Online Volltext: dx.doi.org/
-
Using molecular tweezers to remodel abnormal protein self-assembly and inhibit the toxicity of amyloidogenic proteinsIn: Peptide Self-Assembly: Methods and Protocols / Nilsson, Bradley L.; Doran, Todd M. (Hrsg.) 2018, S. 369 - 386Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Inhibition of Amyloid Beta Aggregation by Functionalized Metal NanoparticlesIn: Mechanisms, Clinical Strategies, and Promising Treatments of Neurodegenerative Diseases: 12th International Conference AD/PD™, Nice, March 2015 ; abstracts / AD/PD ; International Conference on Alzheimer's and Parkinson's Diseases ; Nice, France, March 18-22, 2015 / Fisher, Abraham; Nitsch, Roger M.; Windisch, Manfred (Hrsg.) 2015, S. 372
-
Indicators of Data Quality : Revision of a Guideline for Networked Medical ResearchIn: Quality of Life through Quality of Information / Mantas, John; Andersen, Stig Kjær (Hrsg.) 2012, S. 711 - 715Online Volltext: dx.doi.org/
-
Ammonium, amidinium, guanidinium, and pyridinium cationsIn: Functional Synthetic Receptors / Schrader, Thomas; Hamilton, Andrew D. (Hrsg.) 2005, S. 111 - 164Online Volltext: dx.doi.org/
-
Artificial receptors for the stabilization of b-sheet structuresIn: Highlights in Bioorganic Chemistry / Schmuck, Carsten (Hrsg.) 2004, S. 155 - 171Online Volltext: dx.doi.org/
-
A New Binding Motif for Amidinium Cations : Strong Binding of Amidinium Salts with m-Xylylene Bisphosphonate MoietiesIn: Proceedings of ECSOC / The 4th International Electronic Conference on Synthetic Organic Chemistry, 1–30 Nov 2000, 2000, S. 1458 - 1477Online Volltext: dx.doi.org/
-
A new receptor molecule for lysine and histidine in water - strong binding of basic amino acids by a macrocyclic hostIn: Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry / The 4th International Electronic Conference on Synthetic Organic Chemistry,1–30 Nov 2000, , 2000, S. 1623 - 1637Online Volltext: dx.doi.org/
-
Molecular Imprinting for the Preparation of Enzyme-Analogous PolymersIn: Molecular and Ionic Recognition with Imprinted Polymers 1998, S. 10 - 28Online Volltext: dx.doi.org/
-
Unexpected and facile bridgehead substitution in 4,5,6,7,8,9-hexahydro-5,9-methanopyrimido[4,5-b]azocin-10(1H)-ones : Rapid entry into a series of potential chemotherapeutic agentsIn: Chemistry and Biology of Pteridines and Folates 1997: Proceedings of the Eleventh International Symposium on Pteridines and Folates / Eleventh International Symposium on Pteridines and Folates, Berchtesgaden, Germany, June 15 - 20, 1997 1997, S. 3 - 9
-
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