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Prof. Dr. Andrea Vortkamp

Anschrift
Universitätsstr. 1-5
45141 Essen
Raum
S03 S01 A50
Telefon
+49 201 183 4298
Telefax
+49 201 183 3852
E-Mail
andrea.vortkamp@uni-due.de
Webseite
http://www.uni-due.de/entwicklungsbiologie

Funktionen

  • Universitätsprofessor/in, Entwicklungsbiologie

  • Vorsitzende, Prüfungsausschuss Biologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Neu, Christoph; Wülling, Manuela; Waterkamp, Christoph; Hoffmann, Daniel; Vortkamp, Andrea
    Bath : A Bayesian approach to analyze epigenetic transitions reveals a dual role of H3K27me3 in chondrogenesis
    In: Epigenetics and Chromatin, Jg. 18, 2025, Nr. 1, 38
    DOI (Open Access)
  • Dietmar, Helen F.; Weidmann, Pia A.; Alberton, Paolo; Teichwart, Terrilyn; Gerstner, Matthias; Renkawitz, Tobias; Vortkamp, Andrea; Aszodi, Attila; Richter, Wiltrud; Diederichs, Solvig
    Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genes
    In: Matrix Biology, Jg. 139, 2025, S. 77 – 89
    DOI
  • Le Pennec, Jean; Makshakova, Olga; Nevola, Paola; Fouladkar, Farah; Gout, Evelyne; Machillot, Paul; Friedel-Arboleas, Mélanie; Picart, Catherine; Perez, Serge; Vortkamp, Andrea; Vivès, Romain R.; Migliorini, Elisa
    Glycosaminoglycans exhibit distinct interactions and signaling with BMP2 according to their nature and localization
    In: Carbohydrate Polymers, Jg. 341, 2024, 122294
    DOI (Open Access)
  • Wülling, Manuela; Neu, Christoph; Thiesen, Andrea M.; Kitanovski, Simo; Cao, Yingying; Lange, Anja; Westendorf, Astrid; Hoffmann, Daniel; Vortkamp, Andrea
    Epigenetic mechanisms mediating cell state transitions in chondrocytes
    In: Journal of Bone and Mineral Research (JBMR), Jg. 36, 2021, Nr. 5, S. 968 – 985
    DOI, Online Volltext (Open Access)
  • Gerstner, Matthias; Severmann, Ann-Christine; Chasan, Safak; Vortkamp, Andrea; Richter, Wiltrud
    Heparan sulfate deficiency in cartilage : Enhanced bmp-sensitivity, proteoglycan production and an anti-apoptotic expression signature after loading
    In: International Journal of Molecular Sciences (IJMS), Jg. 22, 2021, Nr. 7, S. 3726
    DOI (Open Access)
  • Severmann, Ann-Christine; Jochmann, Katja; Feller, K.; Bachvarova, Velina; Piombo, Virginia; Stange, Richard; Holzer, Tatjana; Brachvogel, Bent; Esko, Jeffrey D.; Pap, Thomas; Hoffmann, Daniel; Vortkamp, Andrea
    An altered heparan sulfate structure in the articular cartilage protects against osteoarthritis
    In: Osteoarthritis and Cartilage, Jg. 28, 2020, Nr. 7, S. 977 – 987
    DOI (Open Access)
  • Bachvarova, Velina; Dierker, Tabea; Esko, Jeffrey; Hoffmann, Daniel; Kjellen, Lena; Vortkamp, Andrea
    Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate
    In: Matrix Biology, Jg. 39, 2020, S. 43 – 59
    DOI (Open Access)
  • Wülling, Manuela; Schneider, Sabine; Schröther, Verena A.; Waterkamp, Christoph; Hoffmann, Daniel; Vortkamp, Andrea
    Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy
    In: Developmental Biology, Jg. 457, 2020, Nr. 1, S. 104 – 118
    DOI (Open Access)
  • Grüneboom, Anika; Hawwari, Ibrahim; Weidner, Daniela; Culemann, Stephan; Müller, Sylvia; Henneberg, Sophie; Brenzel, Alexandra; Merz, Simon; Bornemann, Lea; Zec, Kristina; Wülling, Manuela; Kling, Lasse; Hasenberg, Mike; Voortmann, Sylvia; Lang, Stefanie; Baum, Wolfgang; Ohs, Alexandra; Kraff, Oliver; Quick, Harald H.; Jäger, Marcus; Landgraeber, Stefan; Dudda, Marcel; Danuser, Renzo; Stein, Jens V.; Rohde, Manfred; Gelse, Kolja; Garbe, Annette I.; Adamczyk, Alexandra; Westendorf, Astrid; Hoffmann, Daniel; Christiansen, Silke; Engel, Daniel Robert; Vortkamp, Andrea; Krönke, Gerhard; Herrmann, Martin; Kamradt, Thomas; Schett, Georg; Hasenberg, Anja; Gunzer, Matthias
    A network of trans-cortical capillaries as mainstay for blood circulation in long bones
    In: Nature Metabolism, Jg. 1, 2019, Nr. 2, S. 236 – 250
    DOI, Online Volltext (Open Access)
  • Wülling, Manuela; Vortkamp, Andrea
    A newly discovered stem cell that keeps bones growing
    In: Nature, Jg. 567, 2019, Nr. 7747, S. 178 – 179
    DOI
  • Schröder, Nadine; Wülling, Manuela; Hoffmann, Daniel; Brand-Saberi, Beate; Vortkamp, Andrea
    Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones
    In: PLoS ONE, Jg. 14, 2019, Nr. 8, S. e0218230
    DOI, Online Volltext (Open Access)
  • Formica, Chiara; Happé, Hester; Veraar, Kimberley AM; Vortkamp, Andrea; Scharpfenecker, Marion; McNeill, Helen; Peters, Dorien JM
    Four-jointed knock-out delays renal failure in an ADPKD model with kidney injury
    In: The Journal of Pathology, Jg. 249, 2019, Nr. 1, S. 114 – 125
    DOI (Open Access)
  • Piombo, Virginia; Jochmann, Katja; Hoffmann, Daniel; Wülling, Manuela; Vortkamp, Andrea
    Signaling systems affecting the severity of multiple osteochondromas
    In: Bone: Official Journal of the International Bone and Mineral Society (IBMS), Jg. 111, 2018, S. 71 – 81
    DOI (Open Access)
  • Wülling, Manuela; Thiesen, Andrea M.; Vortkamp, Andrea
    Epigenetic regulation of chondrocyte differentiation
    18th International Congress of Developmental Biology, 18-22 June, Singapore,
    In: Mechanisms of Development, Jg. 145, 2017, Nr. Supplement: 18th International Congress of Developmental Biology 18-22 June, University Cultural Centre, National University of Singapore, S. S141
    DOI
  • Willie, B.M.; Pap, T.; Perka, C.; Schmidt, C.O.; Eckstein, F.; Arampatzis, A.; Hege, H.-C.; Madry, H.; Vortkamp, Andrea; Duda, G.N.
    OVERLOAD of joints and its role in osteoarthritis : Towards understanding and preventing progression of primary osteoarthritis; English version
    In: Zeitschrift für Rheumatologie, Jg. 76, 2017, Nr. Suppl. 1, S. 1 – 4
    DOI
  • Veistinen, Lotta K.; Mustonen, Tuija; Hasan, Md. Rakibul; Takatalo, Maarit; Kobayashi, Yukiho; Kesper, Dörthe A.; Vortkamp, Andrea; Rice, David P.
    Regulation of calvarial osteogenesis by concomitant de-repression of GLI3 and activation of IHH targets
    In: Frontiers in Physiology, Jg. 8, 2017, S. 1036
    DOI (Open Access)
  • Dierker, Tabea; Bachvarova, Velina; Krause, Yvonne Stefanie; Li, Jin-Ping; Kjellén, Lena; Seidler, Daniela G.; Vortkamp, Andrea
    Altered heparan sulfate structure in Glce-/- mice leads to increased Hedgehog signaling in endochondral bones
    In: Matrix Biology, Jg. 49, 2016, S. 82 – 92
    DOI
  • Hu, Yu; Kim, Ji Hyung; He, Kangmin; Wan, Qi; Kim, Jessica; Flach, Melanie; Kirchhausen, Tom; Vortkamp, Andrea; Winau, Florian
    Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion
    In: Journal of Experimental Medicine (JEM), Jg. 213, 2016, Nr. 12, S. 2759 – 2772
    DOI (Open Access)
  • Mattheij, Nadine J. A.; Kunzelmann, Karl; Vortkamp, Andrea; Schreiber, Rainer; Köhler, Ralf; Wülling, Manuela; Nieswandt, Bernhard; Pircher, Joachim; Castoldi, Elisabetta; van Kruchten, Roger; Braun, Attila
    Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage
    In: The FASEB Journal, Jg. 30, 2016, Nr. 2, S. 727 – 737
    DOI
  • Ousingsawat, Jiraporn; Wanitchakool, Podchanart; Schreiber, Rainer; Wülling, Manuela; Vortkamp, Andrea; Kunzelmann, Karl
    Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1
    In: The Journal of Biological Chemistry (JBC), Jg. 290, 2015, Nr. 10, S. 6270 – 6280
    DOI (Open Access)
  • Severmann, A.-C.; Vortkamp, Andrea
    Hypertrophe Chondrozyten : Programmierter Zelltod oder Stammzellreservoir?
    In: Zeitschrift für Rheumatologie, Jg. 74, 2015, Nr. 10, S. 898 – 901
    DOI
  • Liu, Guoxing; Liu, Guilai; Chen, Hong; Borst, Oliver; Gawaz, Meinrad; Vortkamp, Andrea; Schreiber, Rainer; Kunzelmann, Karl; Lang, Florian
    Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis
    In: Cellular Physiology and Biochemistry, Jg. 37, 2015, Nr. 5, S. 1934 – 1944
    DOI (Open Access)
  • Willie, Bettina M.; Pap, Thomas; Perka, Carsten Frank; Schmidt, Carsten Oliver; Eckstein, Felix; Arampatzis, Adamantios; Hege, Hans Christian; Madry, Henning; Vortkamp, Andrea; Duda, Georg N.
    OVERLOAD – Rolle der Gelenküberlastung in der primären Arthrose : Die Krankheitsprogression verstehen und vermeiden
    In: Zeitschrift für Rheumatologie, Jg. 74, 2015, Nr. 7, S. 618 – 621
    DOI
  • Bandari, Shyam; Exner, Sebastian; Ortmann, Corinna; Bachvarova, Velina; Vortkamp, Andrea; Grobe, Kay
    Sweet on hedgehogs : Regulatory roles of heparan sulfate proteoglycans in hedgehog-dependent cell proliferation and differentiation
    In: Current Protein and Peptide Science, Jg. 16, 2015, Nr. 1, S. 66 – 76
    DOI
  • Chau, M.; Lui, J. C.; Landman, Ellie B. M.; Späth, S.-S.; Vortkamp, Andrea; Baron, J.; Nilsson, O.
    Gene expression profiling reveals similarities between the spatial architectures of postnatal articular and growth plate cartilage
    In: PLoS ONE, Jg. 9, 2014, Nr. 7, S. 0103061
    DOI (Open Access)
  • Jochmann, Katja; Bachvarova, Velina; Vortkamp, Andrea
    Heparan sulfate as a regulator of endochondral ossification and osteochondroma development
    In: Matrix Biology, Jg. 34, 2014, S. 55 – 63
    DOI (Open Access)
  • Dittmann, Kai; Wülling, Manuela; Uhmann, Anja; Dullin, Christian; Hahn, Heidi; Schweyer, Stefan; Vortkamp, Andrea; Wienands, Jürgen
    Inactivation of Patched1 in murine chondrocytes causes spinal fusion without inflammation
    In: Arthritis & Rheumatology, Jg. 66, 2014, Nr. 4, S. 831 – 840
    DOI
  • Jochmann, Katja; Bachvarova, Velina; Vortkamp, Andrea
    Reprint of: Heparan sulfate as a regulator of endochondral ossification and osteochondroma development
    In: Matrix Biology, Jg. 35, 2014, S. 239 – 247
    DOI (Open Access)
  • Rebollido-Rios, Rocio; Bandari, Shyam; Wilms, Christoph; Jakuschev, Stanislav; Vortkamp, Andrea; Grobe, Kay; Hoffmann, Daniel
    Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-Peptidase
    In: PLoS Computational Biology, Jg. 10, 2014, Nr. 7, S. e1003707
    DOI (Open Access)
  • Ehlen, Harald W. A.; Chinenkova, Milana; Moser, Markus; Munter, Hans-Markus; Krause, Yvonne Stefanie; Gross, Stefanie; Brachvogel, Bent; Wülling, Manuela; Kornak, Uwe; Vortkamp, Andrea
    Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues
    In: Journal of Bone and Mineral Research (JBMR), Jg. 28, 2013, Nr. 2, S. 246 – 259
    DOI
  • Wülling, Manuela; Pasdziernik, Markus; Moll, Carina; Thiesen, Andrea; Schneider, Sabine; Johannes, Christian; Vortkamp, Andrea
    The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis
    In: Cell Cycle, Jg. 12, 2013, Nr. 14, S. 2219 – 2232
    DOI
  • Gross, Stefanie; Krause, Yvonne Stefanie; Wülling, Manuela; Vortkamp, Andrea
    Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice
    In: PLoS ONE, Jg. 7, 2012, Nr. 8, S. e43553
    DOI, Online Volltext (Open Access)
  • Veistinen, Lotta; Takatalo, Maarit; Tanimoto, Yukiho; Kesper, Dörthe A.; Vortkamp, Andrea; Rice, David P.C.
    Loss-of-function of Gli3 in mice causes abnormal frontal bone morphology and premature synostosis of the interfrontal suture
    In: Frontiers in Physiology, Jg. 3, 2012, Nr. MAY, S. 121
    DOI (Open Access)
  • Galli, Giorgio Giacomo; Honnens de Lichtenberg, Kristian; Carrara, Matteo; Hans, Wolfgang; Wülling, Manuela; Mentz, Bettina; Multhaupt, Hinke Arnolda; Fog, Cathrine Kolster; Jensen, Klaus Thorleif; Rappsilber, Juri; Vortkamp, Andrea; Coulton, Les; Fuchs, Helmut; Gailus-Durner, Valérie; Hrabě de Angelis, Martin; Calogero, Raffaele Adolfo; Couchman, John Robert; Lund, Anders Henrik
    Prdm5 Regulates Collagen Gene Transcription by Association with RNA Polymerase II in Developing Bone
    In: PLoS Genetics, Jg. 8, 2012, Nr. 5, S. e1002711
    DOI (Open Access)
  • Laufer, Ed; Kesper, Dörthe; Vortkamp, Andrea; King, Perter
    Sonic hedgehog signaling during adrenal development
    In: Molecular and Cellular Endocrinology, Jg. 351, 2012, Nr. 1, S. 19 – 27
    DOI
  • Friedrichs, Melanie; Wirsdöerfer, Florian; Flohe, Stefanie; Schneider, Sabine; Wülling, Manuela; Vortkamp, Andrea
    BMP signaling balances proliferation and differentiation of muscle satellite cell descendants.
    In: BMC Cell Biology, Jg. 12, 2011, 26
    DOI, Online Volltext (Open Access)
  • Jones, Kevin B.; Piombo, Virginia; Searby, Charles; Kurriger, Gail; Yang, Baoli; Grabellus, Florian; Roughley, Peter J.; Morcuende, Jose A.; Buckwalter, Joseph A.; Capecchi, Mario R.; Vortkamp, Andrea; Sheffield, Val C.
    A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 107, 2010, Nr. 5, S. 2054 – 2059
    DOI, Online Volltext (Open Access)
  • Ratzka, Andreas; Mundlos, Stefan; Vortkamp, Andrea
    Expression patterns of sulfatase genes in the developing mouse embryo
    In: Developmental Dynamics, Jg. 239, 2010, Nr. 6, S. 1779 – 1788
    DOI
  • Kesper, Dörthe; Didt-Koziel, Lydia; Vortkamp, Andrea
    Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification.
    In: Developmental Dynamics, Jg. 239, 2010, Nr. 6, S. 1818 – 1826
    DOI
  • Detsch, Rainer; Hagmeyer, Daniel; Neumann, Markus C; Schaefer, Susannne; Vortkamp, Andrea; Wülling, Manuela; Ziegler, Günter; Epple, Matthias
    The resorption of nanocrystalline calcium phosphates by osteoclast-like cells
    In: Acta Biomaterialia, Jg. 6, 2010, Nr. 8, S. 3223 – 3233
    DOI
  • Wülling, Manuela; Vortkamp, Andrea
    Transcriptional networks controlling chondrocyte proliferation and differentiation during endochondral ossification.
    In: Pediatric Nephrology, Jg. 25, 2010, Nr. 4, S. 625 – 631
    DOI
  • Schirling, Corinna; Heseding, Christiane; Heise, Franziska; Kesper, Dörthe; Klebes, Ansgar; Klein-Hitpaß, Ludger; Vortkamp, Andrea; Hoffmann, Daniel; Saumweber, Harald; Ehrenhofer-Murray, Ann
    Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60
    In: Chromosoma, Jg. 119, 2010, Nr. 1, S. 99 – 113
    DOI
  • Wülling, Manuela; Kaiser, Frank J.; Buelens, Laetitia; Braunholz, Diana; Shivdasani, Ramesh A.; Depping, Reinhard; Vortkamp, Andrea
    Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3
    In: Developmental Biology, Jg. 328, 2009, Nr. 1, S. 40 – 53
    DOI
  • Nogai, Hendrik; Rosowski, Mark; Grün, Joachim; Rietz, Anika; Debus, Nils; Schmidt, Gül; Lauster, Carola; Janitz, Michal; Vortkamp, Andrea; Lauster, Roland
    Follistatin antagonizes transforming growth factor-beta3-induced epithelial-mesenchymal transition in vitro: implications for murine palatal development supported by microarray analysis.
    In: Differentiation, Jg. 76, 2008, Nr. 4, S. 404 – 416
  • Ratzka, Andreas; Kalus, Ina; Moser, Markus; Dierks, Thomas; Mundlos, Stefan; Vortkamp, Andrea
    Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development
    In: Developmental Dynamics, Jg. 237, 2008, Nr. 2, S. 339 – 353
    DOI
  • Kantaputra, P.; Miletich, I.; Lüdecke, Hermann-Josef; Suzuki, E. Y.; Praphanphoj, V.; Shivdasani, R.; Wülling, Manuela; Vortkamp, Andrea; Napierala, D.; Sharpe, P. T.
    Tricho-rhino-phalangeal syndrome with supernumerary teeth
    In: Journal of Dental Research: JDR Online, Jg. 87, 2008, Nr. 11, S. 1027 – 1031
    DOI
  • Tagariello, A.; Luther, J.; Streiter, M.; Didt-Koziel, L.; Wülling, Manuela; Surmann-Schmitt, C.; Stock, M.; Adam, N.; Vortkamp, Andrea; Winterpacht, A.
    Ucma - A novel secreted factor represents a highly specific marker for distal chondrocytes
    In: Matrix Biology, Jg. 27, 2008, Nr. 1, S. 3 – 11
    DOI
  • Probst, Barbara; Rock, Rebecca; Gessler, Manfred; Vortkamp, Andrea; Püschel, Andreas W.
    The rodent Four-jointed ortholog Fjx1 regulates dendrite extension
    In: Developmental Biology, Jg. 312, 2007, Nr. 1, S. 461 – 470
    DOI
  • Ehlen, H. W. A.; Buelens, L.A.; Vortkamp, Andrea
    Hedgehog signaling in skeletal development
    In: Birth Defects Research Part C: Embryo Today, Reviews, Jg. 78, 2006, Nr. 3, S. 267 – 279
    DOI
  • Didt-Koziel, L.; Wülling, Manuela; Vortkamp, Andrea
    The role of growth factors in chondrogenesis and osteogenesis
    In: Current Opinion in Orthopaedics, Jg. 17, 2006, S. 405 – 411
    DOI
  • Minina, E.; Schneider, Sabine; Rosowski, M.; Lauster, R.; Vortkamp, Andrea
    Expression of Fgf and Tgfβ signaling related genes during embryonic endochondral ossification
    In: Gene Expression Patterns, Jg. 6, 2005, Nr. 1, S. 102 – 109
    DOI
  • Didt-Koziel, L.; Wülling, Manuela; Schneider, Sabine; Vortkamp, Andrea
    Gli3 has repressing and activating functions downstream of Ihh in regulating two distinct steps of chondrocyte differentiation
    In: Development / Company of Biologists, Jg. 132, 2005, Nr. 23, S. 5249 – 5260
    DOI
  • Zhou, H.; Weskamp, G.; Chesneau, V.; Sahin, U.; Vortkamp, Andrea; Horiuchi, K.; Chiusaroli, R.; Hahn, R.; Wilkes, D.; Fisher, P.; Baron, R.; Manova, R.; Basson, C.T.; Hempstead, B.; Blobel, C.P.
    Essential role for ADAM19 in cardiovascular morphogenesis
    In: Molecular and Cellular Biology (MCB), Jg. 24, 2004, Nr. 1, S. 96 – 104
    DOI
  • Didt-Koziel, L.; Kunath, M.; McMahon, A.P.; Kelly, O.g.; Vortkamp, Andrea
    Ext1 dependent heparan sulfates regulate the range of Ihh signaling during endochondral ossification
    In: Developmental Cell, Jg. 6, 2004, S. 801 – 813
    DOI (Open Access)
  • Wülling, Manuela; Vortkamp, Andrea
    Model systems for human muscoskeletal diseases
    In: Drug Discovery Today: Disease Models, Jg. 1, 2004, Nr. 3, S. 359 – 364
    DOI
  • Tavella, S.; Biticchi, R.; Schito, A.; Minina, E.; Di Martino, D.; Pagano, A.; Vortkamp, Andrea; Horton, W.A.; Cancedda, R.; Garofalo, S.
    Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression
    In: Journal of Bone and Mineral Research (JBMR), Jg. 19, 2004, S. 1678 – 1688
  • Kunath, M.; Luedecke, H.j; Vortkamp, A.
    Expression of Trps1 during mouse embryonic development.
    In: (Mech Dev), Jg. 119 Suppl 1, 2002, S. 117 – 120
  • Minina, E.; Kreschel, C.; Naski, M.C.; Ornitz, D.M.; Vortkamp, A.
    Interaction of FGF, Ihh/Pthlh and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation.
    In: (Dev Cell), Jg. 3, 2002, S. 439 – 449
  • Stricker, S.; Fundele, R.; Vortkamp, A.; Mundlos, S.
    Role of Runx genes in chondrocyte differentiation.
    In: (Dev Biol), Jg. 245, 2002, S. 95 – 108
  • Minina, E.; Wenzel, M.; Kreschel, K.S.; Gaffield, W.; McMahon, A.P.; Vortkamp, A.
    BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation.
    In: Development, Jg. 128, 2001, S. 4523 – 4534
  • Vortkamp, A.
    Interaction of growth factors regulating chondrocyte differentiation in the developing embryo.
    In: Osteoarthritis and Cartilage, Jg. 9, 2001, S. 109 – 117
  • Shan, Zhihong; Nanda, Indrajit; Wang, Yan; Schmid, Michael; Vortkamp, Andrea; Haaf, Thomas
    Sex-specific expression of an evolutionarily conserved male regulatory gene, DMRT1, in birds.
    In: Cytogenetics and Cell Genetics, Jg. 89, 2000, Nr. 3-4, S. 252 – 257
  • Pathi, S.; Rutenberg, J.B.; Johnson, R.L.; Vortkamp, A.
    Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation.
    In: (Dev Biol), Jg. 209, 1999, S. 239 – 253
  • Vortkamp, A.; Pathi, S.; Peretti, G.M.; Caruso, E.M.; Zaleske, D.j.; Tabin, C.j.
    Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair.
    In: (Mech Dev), Jg. 71, 1998, S. 65 – 76
  • Vortkamp, A.
    Defining the skeletal elements.
    In: (Curr Biol), Jg. 7, 1997, S. 104 – 107
  • Wild, A.; Kalff-Suske, M.; Vortkamp, A.; Bornholdt, D.; Konig, R.; Grzeschik, K.H.
    Point mutations in human GLI3 cause Greig syndrome.
    In: (Hum Mol Genet), Jg. 6, 1997, S. 1979 – 1984
  • Lanske, B.; Karaplis, A.C.; Lee, K.; Luz, A.; Vortkamp, A.; Pirro, A.; Karperien, M.; Defize, L.H.K.; Ho, C.; Mulligan, R.C.; Abou-Samra, A.B.; Juppner, H.; Segre, G.V.; Kronenberg, H.M.
    PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth.
    In: Science, Jg. 273, 1996, S. 663 – 666
  • Vortkamp, A.; Lee, K.; Lanske, B.; Segre, G.V.; Kronenberg, H.M.; Tabin, C.j.
    Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein.
    In: Science, Jg. 273, 1996, S. 613 – 622
  • Marigo, V.; Johnson, R.L.; Vortkamp, A.; Tabin, C.j.
    Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.
    In: (Dev Biol), Jg. 180, 1996, S. 273 – 283
  • Molnar, A.; Wu, P.; Largespada, D.A.; Vortkamp, A.; Scherer, S.; Copeland, N.g.; Jenkins, N.A.; Bruns, G.; Georgopoulos, K.
    The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse.
    In: (J Immunol), Jg. 156, 1996, S. 585 – 592
  • Vortkamp, A.; Gessler, M.; Grzeschik, K.H.
    Identification of optimized target sequences for the GLI3 zinc finger protein.
    In: (DNA Cell Biol), Jg. 14, 1995, S. 629 – 634
  • Vortkamp, A.; Heid, C.; Gessler, M.; Grzeschik, K.H.
    Isolation and characterization of a cosmid contig for the GCPS gene region.
    In: (Hum Genet), Jg. 95, 1995, S. 82 – 88
  • Vortkamp, A.; Gessler, M.; Le Paslier, D.; Elaswarapu, R.; Smith, S.; Grzeschik, K.H.
    Isolation of a yeast artificial chromosome contig spanning the Greig cephalopolysyndactyly syndrome (GCPS) gene region.
    In: (Genomics), Jg. 22, 1994, S. 563 – 568
  • van der Hoeven, F.; Schimmang, T.; Vortkamp, A.; Ruther, U.
    Molecular linkage of the morphogenetic mutation add and the zinc finger gene Gli3.
    In: (Mamm Genome), Jg. 4, 1993, S. 276 – 277
  • Vortkamp, A.; Franz, T.; Gessler, M.; Grzeschik, K.H.
    Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt).
    In: (Mamm Genome), Jg. 3, 1992, S. 461 – 463
  • Schimmang, T.; Lemaistre, M.; Vortkamp, A.; Ruther, U.
    Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt).
    In: Development, Jg. 116, 1992, S. 799 – 804
  • Vortkamp, Andrea; Thias, U.; Gessler, M.; Rosenkranz, W.; Kroisel, P. M.; Tommerup, N.; Krüger, G.; Götz, J.; Pelz, L.; Grzeschik, K. H.
    A somatic cell hybrid panel and DNA probes for physical mapping of human chromosome 7p.
    In: Genomics, Jg. 11, 1991, Nr. 3, S. 737 – 743
    Online Volltext
  • Vortkamp, Andrea; Gessler, Manfred; Grzeschik, Karl-Heinz
    GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families.
    In: Nature, Jg. 352, 1991, Nr. 8. August, S. 535 – 540
    Online Volltext

    • Abstracts

  • Gerstner, Matthias; Severmann, Ann-Christine; Vortkamp, Andrea; Richter, Wiltrud
    The Mechano-Response of Tissue-Engineered Heparan-Sulfate Deficient Cartilage : an Anti-Apoptotic expression signature at elevated Proteoglycan Production
    6th Termis World Congress ; 15 - 19 November 2021, Maastricht, The Netherlands,
    In: Tissue Engineering / Part A. Larchmont: Liebert, Jg. 28, 2022, Nr. Supplement 1, S. S499
    DOI (Open Access)
  • Wülling, Manuela; Neu, Christoph; Kitanovski, Simo; Cao, Ying Ying; Lange, Anja; Johnstone, B.; Hoffmann, Daniel; Vortkamp, Andrea
    Epigenetic profiling of articular chondrocytes
    OARSI World Congress on Osteoarthritis, 29.04.-01.05.2021, Virtual,
    In: Osteoarthritis and Cartilage. Amsterdam: Elsevier, Jg. 29, 2021, Nr. Suppl. 1: Abstracts from the Virtual 2021 OARSI World Congress on Osteoarthritis, S. 309
    DOI (Open Access)
  • Severmann, Ann-Christine; Jochmann, Katja; Azar, F.; Holzer, T.; Brachvogel, B.; Fleischhauer, L.; Clausen-Schaumann, H.; Vortkamp, Andrea
    Heparan sulfate proteoglycans and integrin signaling in articular cartilage homeostasis
    In: Osteoarthritis and Cartilage. Amsterdam: Elsevier, Jg. 29, 2021, Nr. Suppl. 1, S. 125 – S126
    DOI (Open Access)
  • Gerstner, M.W; Severmann, Ann-Christine; Vortkamp, Andrea; Richter, W.
    The role of heparan sulfate in the mechano-response of chondrocytes
    In: Osteoarthritis and Cartilage. Amsterdam: Elsevier, Jg. 29, 2021, Nr. Suppl. 1, S. S131
    DOI (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Wülling, Manuela; Vortkamp, Andrea
    Murine Limb Explant Cultures to Assess Cartilage Development
    In: Skeletal Development and Repair: Methods and Protocols / Hilton, Matthew J. (Hrsg.). Berlin: Springer Nature, 2021, S. 139 – 149
    DOI
  • Wülling, Manuela; Vortkamp, Andrea
    Molecular control of cartilage differentiation
    In: Cartilage: Volume 1: Physiology and Development / Grässel, Susanne; Aszódi, Attila (Hrsg.). Cham: Springer International Publishing, 2016, S. 191 – 213
    DOI
  • Wülling, Manuela; Vortkamp, Andrea
    Cartilage explant cultures
    In: Skeletal Development and Repair: Methods and Protocols. Totowa, NJ: Humana Press, 2014, S. 89 – 97
    DOI
  • Wülling, Manuela; Vortkamp, Andrea
    Chondrocyte proliferation and differentiation
    In: Cartilage and bone development and its disorders: 3 Tables / Camacho-Hübner, Cecilia; Nilsson, Ola G.; Sävendahl, Lars; 4th ESPE Advanced Seminar in Developmental Endocrinology, Stockholm, June 30 - July 1, 2010. Basel [u.a.]: S. Karger AG, 2011, S. 1 – 11
  • Vortkamp, Andrea
    Regulation der Chondrozytendifferenzierung in der Wachstumsfuge : Parakrine Signalsysteme
    In: Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstörungen / Ganten, Detlev; Ruckpaul, Klaus; Köhrle, Josef (Hrsg.). Berlin: Springer, 2006, S. 461 – 478
    DOI
  • Vortkamp, Andrea
    The Indian Hedgehog — PTHrP System in Bone Development
    In: Of Fish, Fly, Worm, and Man: Lessons from Developmental Biology for Human Gene Function and Disease. Berlin: Springer, 2000, S. 191 – 209
    DOI