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Prof. Dr. med. Erich Gulbins

Telefon
+49 201 723 3118
Telefax
+49 201 723 59 74
E-Mail
erich.gulbins@uni-due.de
Webseite
http://www.uni-due.de/imb/gulbins_res.html

Funktionen

  • Geschäftsführende/r Direktor/in, Institut für Molekularbiologie (Tumorforschung)

  • Professorinnen/Professoren, Fachbereichsrat

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Mohamud Yusuf, Ayan; Borbor, Mina; Hussner, Tanja; Weghs, Carolin; Kaltwasser, Britta; Pillath-Eilers, Matthias; Walkenfort, Bernd; Kolesnick, Richard; Gulbins, Erich; Hermann, Dirk M.; Brockmeier, Ulf
    Acid sphingomyelinase inhibition induces cerebral angiogenesis post-ischemia/reperfusion in an oxidative stress-dependent way and promotes endothelial survival by regulating mitochondrial metabolism
    In: Cell Death and Disease Jg. 15 (2024) Nr. 9, 650
    Online Volltext: dx.doi.org/ (Open Access)
  • Prosdocimi, Elena; Carpanese, Veronica; Todesca, Luca Matteo; Varanita, Tatiana; Bachmann, Magdalena; Festa, Margherita; Bonesso, Daniele; Perez-Verdaguer, Mireia; Carrer, Andrea; Velle, Angelo; Peruzzo, Roberta; Muccioli, Silvia; Doni, Davide; Leanza, Luigi; Costantini, Paola; Stein, Frank; Rettel, Mandy; Felipe, Antonio; Edwards, Michael J.; Gulbins, Erich; Cendron, Laura; Romualdi, Chiara; Checchetto, Vanessa; Szabo, Ildiko
    BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
    In: Science Advances Jg. 10 (2024) Nr. 36, eadn9361
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Yuqing; Riehle, Andrea; Pollmeier, Barbara; Kadow, Stephanie; Schumacher, Fabian; Drab, Marek; Kleuser, Burkhard; Gulbins, Erich; Grassmé, Heike
    Caveolin-1 affects early mycobacterial infection and apoptosis in macrophages and mice
    In: Tuberculosis Jg. 147 (2024) 102493
    Online Volltext: dx.doi.org/ (Open Access)
  • Thümmler, Laura; Beckmann, Nadine; Sehl, Carolin; Soddemann, Matthias; Braß, Peer; Bormann, Maren; Brochhagen, Leonie; Elsner, Carina; Hoertel, Nicolas; Cougoule, Céline; Ciesek, Sandra; Widera, Marek; Dittmer, Ulf; Lindemann, Monika; Horn, Peter A.; Witzke, Oliver; Kadow, Stephanie; Kamler, Markus; Gulbins, Erich; Becker, Katrin Anne; Krawczyk, Adalbert
    Fluoxetine and Sertraline Potently Neutralize the Replication of Distinct SARS-CoV-2 Variants
    In: Viruses Jg. 16 (2024) Nr. 4, 545
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Judith; Soddemann, Matthias; Edwards, Michael J.; Wilson, Gregory C.; Lang, Karl S.; Gulbins, Erich
    Sphingosine Prevents Rhinoviral Infections
    In: International Journal of Molecular Sciences (IJMS) Jg. 25 (2024) Nr. 5, 2486
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Patel, Sameer H.; Wilson, Gregory C.; Wu, Yuqing; Keitsch, Simone; Wilker, Barbara; Mattarei, Andrea; Ahmad, Syed A.; Szabo, Ildiko; Gulbins, Erich
    Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions
    In: Journal of Molecular Medicine Jg. 102 (2024) Nr. 7, S. 947 - 959
    Online Volltext: dx.doi.org/ (Open Access)
  • May, Helene; Liu, Yongjie; Kadow, Stephanie; Edwards, Michael J.; Keitsch, Simone; Wilker, Barbara; Kamler, Markus; Grassmé, Heike; Wu, Yuqing; Gulbins, Erich
    Sphingosine kills intracellular Pseudomonas aeruginosa and Staphylococcus aureus
    In: Pathogens and Disease Jg. 82 (2024) ftae016
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Yongjie; Wu, Yuqing; Leukers, Lydia; Schimank, Kristin; Wilker, Jonathan; Wißmann, Andreas; Rauen, Ursula; Pizanis, Nikolaus; Taube, Christian; Koch, Achim; Gulbins, Erich; Kamler, Markus
    Treatment of Staphylococcus aureus infection with sphingosine in ex vivo perfused and ventilated lungs
    In: The Journal of Heart and Lung Transplantation Jg. 43 (2024) Nr. 1, S. 100 - 110
    Online Volltext: dx.doi.org/ (Open Access)
  • Pfeilschifter, Josef; Gulbins, Erich
    Tribute to Andrea Huwiler (1966–2023)
    In: Pflügers Archiv: European Journal of Physiology (2024) in press
    Online Volltext: dx.doi.org/ (Open Access)
  • Wiehlmann, Lutz; Klockgether, Jens; Hammerbacher, Anna-Silke; Salunkhe, Prabhakar; Horatzek, Sonja; Munder, Antje; Peilert, Janno Florian; Gulbins, Erich; Eberl, Leo; Tümmler, Burkhard
    A VirB4 ATPase of the mobile accessory genome orchestrates core genome-encoded features of physiology, metabolism, and virulence of Pseudomonas aeruginosa TBCF10839
    In: Frontiers in Cellular and Infection Microbiology Jg. 13 (2023) 1234420
    Online Volltext: dx.doi.org/ (Open Access)
  • Wilson, Gregory C.; Patel, Sameer H.; Wang, Jiang; Xu, Kui; Turner, Kevin M.; Becker-Flegler, Katrin; Carpinteiro, Alexander; Szabo, Ildiko; Ahmad, Syed A.; Gulbins, Erich
    Acid sphingomyelinase expression is associated with survival in resectable pancreatic ductal adenocarcinoma
    In: Journal of Molecular Medicine Jg. 101 (2023) Nr. 7, S. 891 - 903
    Online Volltext: dx.doi.org/ (Open Access)
  • Choi, Byung Jo; Park, Min Hee; Park, Kang Ho; Han, Wan Hui; Yoon, Hee Ji; Jung, Hye Yoon; Hong, Ju Yeon; Chowdhury, Md Riad; Kim, Kyung Yeol; Lee, Jihoon; Song, Im-Sook; Pang, Minyeong; Choi, Min-Koo; Gulbins, Erich; Reichel, Martin; Kornhuber, Johannes; Hong, Chang-Won; Kim, Changho; Kim, Seung Hyun; Schuchman, Edward H.; Jin, Hee Kyung; Bae, Jae-sung
    Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease
    In: Nature Communications Jg. 14 (2023) Nr. 1, 1631
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoertel, Nicolas; Rezaei, Katayoun; Sánchez-Rico, Marina; Delgado-Álvarez, Alfonso; Kornhuber, Johannes; Gulbins, Erich; Olfson, Mark; Ouazana-Vedrines, Charles; Carpinteiro, Alexander; Cougoule, Céline; Becker, Katrin Anne; Alvarado, Jesús M.; Limosin, Frédéric
    Medications Modulating the Acid Sphingomyelinase/Ceramide System and 28-Day Mortality among Patients with SARS-CoV-2: An Observational Study
    In: Pharmaceuticals Jg. 16 (2023) Nr. 8, 1107
    Online Volltext: dx.doi.org/ (Open Access)
  • Schnitker, Fabian; Liu, Yongjie; Keitsch, Simone; Soddemann, Matthias; Verhasselt, Hedda Luise; Kehrmann, Jan; Grassmé, Heike; Kamler, Markus; Gulbins, Erich; Wu, Yuqing
    Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to Mycobacterium abscessus Infections
    In: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 18, 14004
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Hoertel, Nicolas; Sánchez-Rico, Marina; de la Muela, Pedro; Abellán, Miriam; Blanco, Carlos; Leboyer, Marion; Cougoule, Céline; Gulbins, Erich; Kornhuber, Johannes; Carpinteiro, Alexander; Becker, Katrin Anne; Vernet, Raphaël; Beeker, Nathanaël; Neuraz, Antoine; Alvarado, Jesús M.; Herrera-Morueco, Juan José; Airagnes, Guillaume; Lemogne, Cédric; Limosin, Frédéric; Ancel, Pierre-Yves; Bauchet, Alain; Benoit, Vincent; Bernaux, Mélodie; Bellamine, Ali; Bey, Romain; Bourmaud, Aurélie; Breant, Stéphane; Burgun, Anita; Carrat, Fabrice; Caucheteux, Charlotte; Champ, Julien; Cormont, Sylvie; Daniel, Christel; Dubiel, Julien; Ducloas, Catherine; Esteve, Loic; Frank, Marie; Garcelon, Nicolas; Gramfort, Alexandre; Griffon, Nicolas; Grisel, Olivier; Guilbaud, Martin; Hassen-Khodja, Claire; Hemery, François; Hilka, Martin; Jannot, Anne Sophie; Lambert, Jerome; Layese, Richard; Leblanc, Judith; Lebouter, Léo; Lemaitre, Guillaume; Leprovost, Damien; Lerner, Ivan; Sallah, Kankoe Levi; Maire, Aurélien; Mamzer, Marie-France; Martel, Patricia; Mensch, Arthur; Moreau, Thomas; Orlova, Nina; Paris, Nicolas; Rance, Bastien; Ravera, Hélène; Rozes, Antoine; Salamanca, Elisa; Sandrin, Arnaud; Serre, Patricia; Tannier, Xavier; Treluyer, Jean-Marc; Van Gysel, Damien; Varoquaux, Gaël; Vie, Jill Jen; Wack, Maxime; Wajsburt, Perceval; Wassermann, Demian; Zapletal, Eric
    Risk of Death in Individuals Hospitalized for COVID-19 With and Without Psychiatric Disorders : An Observational Multicenter Study in France
    In: Biological Psychiatry Global Open Science Jg. 3 (2023) Nr. 1, S. 56 - 67
    Online Volltext: dx.doi.org/ (Open Access)
  • Wilson, Gregory C.; Keitsch, Simone; Soddemann, Matthias; Wilker, Barbara; Edwards, Michael J.; Gulbins, Erich
    Role of Tyrosine Nitrosylation in Stress-Induced Major Depressive Disorder: Mechanisms and Implications
    In: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 19, 14626
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Patel, Sameer H.; Bachmann, Magdalena; Kadow, Stephanie; Wilson, Gregory C.; Abdel-Salam, Mostafa M. L.; Xu, Kui; Keitsch, Simone; Soddemann, Matthias; Wilker, Barbara; Becker, Katrin Anne; Carpinteiro, Alexander; Ahmad, Syed A.; Szabo, Ildiko; Gulbins, Erich
    Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivo
    In: Journal of Molecular Medicine Jg. 101 (2023) Nr. 3, S. 295 - 310
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Anne; Görtz, Gina-Eva; Gulbins, Erich; Eckstein, Anja
    Sphingolipids in thyroid eye disease
    In: Frontiers in Endocrinology Jg. 14 (2023) 1170884
    Online Volltext: dx.doi.org/ (Open Access)
  • Mohamud Yusuf, Ayan; Hagemann, Nina; Zhang, Xiaoni; Zafar, Maria; Hussner, Tanja; Bromkamp, Carolin; Martiny, Carlotta; Tertel, Tobias; Börger, Verena; Schumacher, Fabian; Solari, Fiorella A.; Hasenberg, Mike; Kleinschnitz, Christoph; Döppner, Thorsten R.; Kleuser, Burkhard; Sickmann, Albert; Gunzer, Matthias; Giebel, Bernd; Kolesnick, Richard; Gulbins, Erich; Hermann, Dirk M.
    Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles
    In: Basic Research in Cardiology Jg. 117 (2022) Nr. 1, 43
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoertel, Nicolas; Sánchez-Rico, Marina; Kornhuber, Johannes; Gulbins, Erich; Reiersen, Angela M.; Lenze, Eric J.; Fritz, Bradley A.; Jalali, Farid; Mills, Edward J.; Cougoule, Céline; Carpinteiro, Alexander; Mühle, Christiane; Becker, Katrin Anne; Boulware, David R.; Blanco, Carlos; Alvarado, Jesús M.; Strub-Wourgaft, Nathalie; Lemogne, Cédric; Limosin, Frédéric
    Antidepressant Use and Its Association with 28-Day Mortality in Inpatients with SARS-CoV-2 : Support for the FIASMA Model against COVID-19
    In: Journal of Clinical Medicine (JCM) Jg. 11 (2022) Nr. 19, 5882
    Online Volltext: dx.doi.org/ (Open Access)
  • Carstens, Henning; Kalka, Katharina; Verhaegh, Rabea; Schumacher, Fabian; Soddemann, Matthias; Wilker, Barbara; Keitsch, Simone; Sehl, Carolin; Kleuser, Burkhard; Hübler, Michael; Rauen, Ursula; Becker, Anne Katrin; Koch, Achim; Gulbins, Erich; Kamler, Markus
    Antimicrobial effects of inhaled sphingosine against Pseudomonas aeruginosa in isolated ventilated and perfused pig lungs
    In: PLoS ONE Jg. 17 (2022) e0271620
    Online Volltext: dx.doi.org/ (Open Access)
  • Péricat, David; Leon-Icaza, Stephen Adonai; Sanchez Rico, Marina; Mühle, Christiane; Zoicas, Iulia; Schumacher, Fabian; Planès, Rémi; Mazars, Raoul; Gros, Germain; Carpinteiro, Alexander; Becker, Katrin Anne; Izopet, Jacques; Strub-Wourgaft, Nathalie; Sjö, Peter; Neyrolles, Olivier; Kleuser, Burkhard; Limosin, Frédéric; Gulbins, Erich; Kornhuber, Johannes; Meunier, Etienne; Hoertel, Nicolas; Cougoule, Céline
    Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 21, S. 13623
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoertel, Nicolas; Sánchez-Rico, Marina; Gulbins, Erich; Kornhuber, Johannes; Carpinteiro, Alexander; Abellán, Miriam; de la Muela, Pedro; Vernet, Raphaël; Beeker, Nathanaël; Neuraz, Antoine; Delcuze, Aude; Alvarado, Jesús M; Cougoule, Céline; Meneton, Pierre; Limosin, Frédéric
    Association between FIASMA psychotropic medications and reduced risk of intubation or death in individuals with psychiatric disorders hospitalized for severe COVID-19 : an observational multicenter study
    In: Translational Psychiatry Jg. 12 (2022) 90
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoertel, Nicolas; Sánchez-Rico, Marina; Gulbins, Erich; Kornhuber, J.; Vernet, R.; Beeker, N.; Neuraz, A.; Blanco, C.; Olfson, M.; Airagnes, G.; Lemogne, C.; Alvarado, Jesus Maria; Arnaout, M.; Cougoule, C.; Meneton, P.; Limosin, F.
    Association between benzodiazepine receptor agonist use and mortality in patients hospitalised for COVID-19 : a multicentre observational study
    In: Epidemiology and Psychiatric Sciences Jg. 31 (2022) e18
    Online Volltext: dx.doi.org/ (Open Access)
  • Westhölter, Dirk; Schumacher, Fabian; Wülfinghoff, Nuria; Sutharsan, Sivagurunathan; Strassburg, Svenja; Kleuser, Burkhard; Horn, Peter; Reuter, Sebastian; Gulbins, Erich; Taube, Christian; Welsner, Matthias
    CFTR modulator therapy alters plasma sphingolipid profiles in people with cystic fibrosis
    In: Journal of Cystic Fibrosis Jg. 21 (2022) Nr. 4, S. 713 - 720
    Online Volltext: dx.doi.org/
  • Hose, Matthias; Günther, Anne; Naser, Eyad; Schumacher, Fabian; Schönberger, Tina; Falkenstein, Julia; Papadamakis, Athanasios; Kleuser, Burkhard; Becker, Katrin Anne; Gulbins, Erich; Haimovitz-Friedman, Adriana; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    Cell-intrinsic ceramides determine T cell function during melanoma progression
    In: eLife Jg. 11 (2022) e83073
    Online Volltext: dx.doi.org/ (Open Access)
  • Schumacher, Fabian; Edwards, Michael J.; Mühle, Christiane; Carpinteiro, Alexander; Wilson, Greg C.; Wilker, Barbara; Soddemann, Matthias; Keitsch, Simone; Scherbaum, Norbert; Müller, Bernhard W.; Lang, Undine E.; Linnemann, Christoph; Kleuser, Burkhard; Müller, Christian P.; Kornhuber, Johannes; Gulbins, Erich
    Ceramide levels in blood plasma correlate with major depressive disorder severity and its neutralization abrogates depressive behavior in mice
    In: The Journal of Biological Chemistry (JBC) Jg. 298 (2022) Nr. 8, 102185
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoertel, Nicolas; Sánchez-Rico, Marina; Herrera-Morueco, Juan José; de la Muela, Pedro; Gulbins, Erich; Kornhuber, Johannes; Carpinteiro, Alexander; Becker-Flegler, Katrin; Cougoule, Céline; Limosin, Frédéric
    Comorbid medical conditions are a key factor to understand the relationship between psychiatric disorders and COVID-19-related mortality : Results from 49,089 COVID-19 inpatients
    In: Molecular Psychiatry Jg. 27 (2022) Nr. 3, S. 1278 - 1280
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Weiwei; Wilson, Gregory C.; Bachmann, Magdalena; Wang, Jiang; Mattarei, Andrea; Paradisi, Cristina; Edwards, Michael J.; Szabo, Ildiko; Gulbins, Erich; Ahmad, Syed A.; Patel, Sameer H.
    Inhibition of a Mitochondrial Potassium Channel in Combination with Gemcitabine and Abraxane Drastically Reduces Pancreatic Ductal Adenocarcinoma in an Immunocompetent Orthotopic Murine Model
    In: Cancers Jg. 14 (2022) Nr. 11, 2618
    Online Volltext: dx.doi.org/ (Open Access)
  • Koch, Achim; Pizanis, Nikolaus; Bessa, Vasiliki; Herbstreit, Frank; Gulbins, Erich; Aigner, Clemens; Kamler, Markus
    Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection
    In: The Thoracic and Cardiovascular Surgeon Reports Jg. 11 (2022) Nr. 1, S. e23 - e26
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Kadow, Stephanie; Schumacher, Fabian; Kramer, Melanie; Hessler, Gabriele; Scholtysik, René; Oubari, Sara; Johansson, Patricia; Hüttmann, Andreas; Reinhardt, Hans Christian; Kleuser, Burkhard; Zoratti, Mario; Mattarei, Andrea; Szabò, Ildiko; Gulbins, Erich; Carpinteiro, Alexander
    Mitochondrial Kv1.3 Channels as Target for Treatment of Multiple Myeloma
    In: Cancers Jg. 14 (2022) Nr. 8, 1955
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Edwards, Michael J.; Wilson, Gregory C.; Keitsch, Simone; Soddemann, Matthias; Wilker, Barbara; Müller, Christian P.; Kornhuber, Johannes; Gulbins, Erich
    Molecular targets of endothelial phosphatidic acid regulating major depressive disorder
    In: Journal of Neurochemistry Jg. 163 (2022) Nr. 4, S. 357 - 369
    Online Volltext: dx.doi.org/ (Open Access)
  • Hagmann, Henning; Khayyat, Naghmeh Hassanzadeh; Oezel, Cem; Papadakis, Antonios; Kuczkowski, Alexander; Benzing, Thomas; Gulbins, Erich; Dryer, Stuart; Brinkkoetter, Paul T.
    Paraoxonase 2 (PON2) Deficiency Reproduces Lipid Alterations of Diabetic and Inflammatory Glomerular Disease and Affects TRPC6 Signaling
    In: Cells Jg. 11 (2022) Nr. 22, 3625
    Online Volltext: dx.doi.org/ (Open Access)
  • Severin, Filippo; Urbani, Andrea; Varanita, Tatiana; Bachmann, Magdalena; Azzolini, Michele; Martini, Veronica; Pizzi, Marco; Tos, Angelo Paolo Dei; Frezzato, Federica; Mattarei, Andrea; Ghia, Paolo; Bertilaccio, Maria Teresa Sabrina; Gulbins, Erich; Paradisi, Cristina; Zoratti, Mario; Semenzato, Gianpietro Carlo; Leanza, Luigi; Trentin, Livio; Szabò, Ildiko
    Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model
    In: Journal of Experimental & Clinical Cancer Research Jg. 41 (2022) Nr. 1, 64
    Online Volltext: dx.doi.org/ (Open Access)
  • Bachmann, Magdalena; Rossa, Andrea; Varanita, Tatiana; Fioretti, Bernard; Biasutto, Lucia; Milenkovic, Stefan; Checchetto, Vanessa; Peruzzo, Roberta; Ahmad, Syed A.; Patel, Sameer H.; Lukowski, Robert; Edwards, Michael J.; Ceccarelli, Matteo; Gulbins, Erich; Zoratti, Mario; Mattarei, Andrea; Szabo, Ildiko
    Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo
    In: Cell Death and Disease Jg. 13 (2022) Nr. 12, 1055
    Online Volltext: dx.doi.org/ (Open Access)
  • Kalinichenko, Liubov S.; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P.
    Sphingolipid control of cognitive functions in health and disease
    In: Progress in Lipid Research Jg. 86 (2022) 101162
    Online Volltext: dx.doi.org/
  • Arani, Fahimeh Hashemi; Kadow, Stephanie; Kramer, Melanie; Keitsch, Simone; Kirchhoff, Lisa; Schumacher, Fabian; Kleuser, Burkhard; Rath, Peter-Michael; Gulbins, Erich; Carpinteiro, Alexander
    Sphingosine as a new antifungal agent against Candida and Aspergillus spp.
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 24, 15510
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schumacher, Fabian; Carpinteiro, Alexander; Edwards, Michael J.; Wilson, Gregory C.; Keitsch, Simone; Soddemann, Matthias; Wilker, Barbara; Kleuser, Burkhard; Becker, Katrin Anne; Müller, Christian P.; Kornhuber, Johannes; Gulbins, Erich
    Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma
    In: Journal of Molecular Medicine Jg. 100 (2022) Nr. 10, S. 1493 - 1508
    Online Volltext: dx.doi.org/ (Open Access)
  • Günther, Anne; Hose, Matthias; Abberger, Hanna; Schumacher, Fabian; Veith, Ylva; Kleuser, Burkhard; Matuschewski, Kai; Lang, Karl Sebastian; Gulbins, Erich; Buer, Jan; Westendorf, Astrid M.; Hansen, Wiebke
    The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis
    In: eLife Jg. 11 (2022) e77975
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Kornhuber, Johannes; Hoertel, Nicolas; Gulbins, Erich
    The acid sphingomyelinase/ceramide system in COVID-19
    In: Molecular Psychiatry Jg. 27 (2022) Nr. 1, S. 307 - 314
    Online Volltext: dx.doi.org/ (Open Access)
  • Becker, Katrin Anne; Verhaegh, Rabea; Verhasselt, Hedda-Luise; Keitsch, Simone; Soddemann, Matthias; Wilker, Barbara; Wilson, Gregory C.; Buer, Jan; Ahmad, Syed A.; Edwards, Michael J.; Gulbins, Erich
    Acid ceramidase rescues cystic fibrosis mice from pulmonary infections
    In: Infection and Immunity Jg. 89 (2021) Nr. 2, S. e00677 - 20
    Online Volltext: dx.doi.org/ (Open Access)
  • Luong, Trang Thi Doan; Tuffaha, Rashad; Schuchardt, Mirjam; Moser, Barbara; Schelski, Nadeshda; Boehme, Beate; Gollmann-Tepeköylü, Can; Schramm, Clara; Holfeld, Johannes; Pieske, Burkert; Gulbins, Erich; Tölle, Markus; Van Der Giet, Markus; Lang, Florian; Eckardt, Kai-Uwe; Voelkl, Jakob; Alesutan, Ioana
    Acid sphingomyelinase promotes SGK1-dependent vascular calcification
    In: Clinical Science Jg. 135 (2021) Nr. 3, S. 515 - 534
    Online Volltext: dx.doi.org/ (Open Access)
  • Seitz, Aaron; Baker, Jennifer E.; Levinsky, Nick C.; Morris, Mackenzie C.; Edwards, Michael J.; Gulbins, Erich; Blakeman, Thomas C.; Rodriquez, Dario; Branson, Richard D.; Goodman, Michael
    Antimicrobial coating prevents ventilator-associated pneumonia in a 72 hour large animal model
    In: Journal of Surgical Research Jg. 267 (2021) S. 424 - 431
    Online Volltext: dx.doi.org/
  • Hoertel, Nicolas; Sánchez-Rico, Marina; Gulbins, Erich; Kornhuber, Johannes; Carpinteiro, Alexander; Lenze, Eric J.; Reiersen, Angela M.; Abellán, Miriam; de la Muela, Pedro; Vernet, Raphaël; Blanco, Carlos; Cougoule, Céline; Neuraz, Antoine; Gorwood, Philip; Alvarado, Jesús M.; Meneton, Pierre; Limosin, Frédéric; Ancel, Pierre-Yves; Bauchet, Alain; Beeker, Nathanaël; Beeker, Nathanaël; Benoit, Vincent; Bernaux, Mélodie; Bellamine, Ali; Bey, Romain; Bourmaud, Aurélie; Breant, Stéphane; Burgun, Anita; Carrat, Fabrice; Caucheteux, Charlotte; Champ, Julien; Cormont, Sylvie; Daniel, Christel; Dubiel, Julien; Ducloas, Catherine; Esteve, Loic; Frank, Marie; Garcelon, Nicolas; Gramfort, Alexandre; Griffon, Nicolas; Grisel, Olivier; Guilbaud, Martin; Hassen-Khodja, Claire; Hemery, François; Hilka, Martin; Sophie Jannot, Anne; Lambert, Jerome; Layese, Richard; Leblanc, Judith; Lebouter, Léo; Lemaitre, Guillaume; Leprovost, Damien; Lerner, Ivan; Levi Sallah, Kankoe; Maire, Aurélien; Mamzer, Marie-France; Martel, Patricia; Mensch, Arthur; Moreau, Thomas; Neuraz, Antoine; Orlova, Nina; Paris, Nicolas; Rance, Bastien; Ravera, Hélène; Rozes, Antoine; Salamanca, Elisa; Sandrin, Arnaud; Serre, Patricia; Tannier, Xavier; Treluyer, Jean-Marc; van Gysel, Damien; Varoquaux, Gaël; Vie, Jill Jen; Wack, Maxime; Wajsburt, Perceval; Wassermann, Demian; Zapletal, Eric
    Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: An Observational Multicenter Study
    In: Clinical Pharmacology & Therapeutics Jg. 110 (2021) Nr. 6, S. 1498 - 1511
    Online Volltext: dx.doi.org/ (Open Access)
  • Beckmann, Nadine; Schumacher, Fabian; Kleuser, Burkhard; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C.
    Burn Injury Impairs Neutrophil Chemotaxis Through Increased Ceramide
    In: Shock Jg. 56 (2021) Nr. 1, S. 125 - 132
    Online Volltext: dx.doi.org/
  • Frankowska, Małgorzata; Jesus, Fernando M.; Mühle, Christiane; Pacheco, Jéssica V.N.; Maior, Rafael S.; Sadakierska-Chudy, Anna; Smaga, Irena; Piechota, Marcin; Kalinichenko, Liubov S.; Gulbins, Erich; Kornhuber, Johannes; Filip, Małgorzata; Müller, Christian P.; Barros, Marilia
    Cocaine attenuates acid sphingomyelinase activity during establishment of addiction-related behavior : A translational study in rats and monkeys
    In: Addiction Biology Jg. 26 (2021) Nr. 3, S. e12955
    Online Volltext: dx.doi.org/ (Open Access)
  • Peruzzo, Roberta; Mattarei, Andrea; Azzolini, Michele; Becker-Flegler, Katrin Anne; Romio, Matteo; Rigoni, Giovanni; Carrer, Andrea; Biasutto, Lucia; Parrasia, Sofia; Kadow, Stephanie; Managò, Antonella; Urbani, Andrea; Rossa, Andrea; Semenzato, Gianpietro; Soriano, Maria Eugenia; Trentin, Livio; Ahmad, Syed; Edwards, Michael; Gulbins, Erich; Paradisi, Cristina; Zoratti, Mario; Leanza, Luigi; Szabò, Ildikò
    Corrigendum to: “Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family”
    In: Redox Biology Jg. 45 (2021) 102036
    Online Volltext: dx.doi.org/ (Open Access)
  • Becker, Katrin; Carpinteiro, Alexander; Hoffmann, Markus; Pöhlmann, Stefan; Kornhuber, Johannes; Gulbins, Erich
    Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells
    In: STAR Protocols Jg. 2 (2021) Nr. 1, S. 100356
    Online Volltext: dx.doi.org/ (Open Access)
  • Carstens, Henning; Kalka, Katharina; Verhaegh, Rabea; Schumacher, Fabian; Soddemann, Matthias; Wilker, Barbara; Keitsch, Simone; Sehl, Carolin; Kleuser, Burkhard; Wahlers, Thorsten; Reiner, Gerald; Koch, Achim; Rauen, Ursula; Gulbins, Erich; Kamler, Markus
    Inhaled sphingosine has no adverse side effects in isolated ventilated and perfused pig lungs
    In: Scientific Reports Jg. 11 (2021) Nr. 1, 18607
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Carpinteiro, Alexander; Gripp, Barbara; Hoffmann, Markus; Pöhlmann, Stefan; Hoertel, Nicolas; Edwards, Michael J.; Kamler, Markus; Kornhuber, Johannes; Becker, Katrin Anne; Gulbins, Erich
    Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells
    In: The Journal of Biological Chemistry (JBC) Jg. 296 (2021) 100701
    Online Volltext: dx.doi.org/ (Open Access)
  • Gardner, Aaron Ions; Wu, Yuqing; Verhaegh, Rabea; Liu, Yongjie; Wilker, Barbara; Soddemann, Matthias; Keitsch, Simone; Edwards, Michael J.; Haq, Iram J.; Kamler, Markus; Becker, Katrin Anne; Brodlie, Malcolm; Gulbins, Erich
    Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis
    In: The Journal of Biological Chemistry (JBC) Jg. 296 (2021) 100650
    Online Volltext: dx.doi.org/ (Open Access)
  • Checchetto, Vanessa; Leanza, Luigi; De Stefani, Diego; Rizzuto, Rosario; Gulbins, Erich; Szabo, Ildiko
    Mitochondrial K⁺ channels and their implications for disease mechanisms
    In: Pharmacology & Therapeutics Jg. 227 (2021) 107874
    Online Volltext: dx.doi.org/
  • Rhein, Cosima; Zoicas, Iulia; Marx, Lena M.; Zeitler, Stefanie; Hepp, Tobias; von Zimmermann, Claudia; Mühle, Christiane; Richter-Schmidinger, Tanja; Lenz, Bernd; Erim, Yesim; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes
    Mrna expression of smpd1 encoding acid sphingomyelinase decreases upon antidepressant treatment
    In: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 11, 5700
    Online Volltext: dx.doi.org/ (Open Access)
  • Kalinichenko, Liubov S.; Abdel-Hafiz, Laila; Wang, An-Li; Mühle, Christiane; Rösel, Nadine; Schumacher, Fabian; Kleuser, Burkhard; Smaga, Irena; Frankowska, Malgorzata; Filip, Malgorzata; Schaller, Gerd; Richter-Schmidinger, Tanja; Lenz, Bernd; Gulbins, Erich; Kornhuber, Johannes; Oliveira, André W. C.; Barros, Marilia; Huston, Joseph P.; Müller, Christian P.
    Neutral Sphingomyelinase is an Affective Valence-Dependent Regulator of Learning and Memory
    In: Cerebral Cortex Jg. 31 (2021) Nr. 2, S. 1316 - 1333
    Online Volltext: dx.doi.org/
  • Kalinichenko, Liubov S.; Wang, An-Li; Mühle, Christiane; Abdel-Hafiz, Laila; Gulbins, Erich; Kornhuber, Johannes; Oliveira, André W. C.; Barros, Marilia; Huston, Joseph P.; Müller, Christian P.
    Neutral ceramidase is a marker for cognitive performance in rats and monkeys
    In: Pharmacological Reports Jg. 73 (2021) Nr. 1, S. 73 - 84
    Online Volltext: dx.doi.org/ (Open Access)
  • Kalinichenko, Liubov S.; Mühle, Christiane; Jia, Tianye; Anderheiden, Felix; Datz, Maria; Eberle, Anna-Lisa; Eulenburg, Volker; Granzow, Jonas; Hofer, Martin; Hohenschild, Julia; Huber, Sabine E.; Kämpf, Stefanie; Kogias, Georgios; Lacatusu, Laura; Lugmair, Charlotte; Taku, Stephen Mbu; Meixner, Doris; Tesch, Nina; Praetner, Marc; Rhein, Cosima; Sauer, Christina; Scholz, Jessica; Ulrich, Franziska; Valenta, Florian; Weigand, Esther; Werner, Markus; Tay, Nicole; Mc Veigh, Conor J.; Haase, Jana; Wang, An-Li; Abdel-Hafiz, Laila; Huston, Joseph P.; Smaga, Irena; Frankowska, Malgorzata; Filip, Malgorzata; Lourdusamy, Anbarasu; Kirchner, Philipp; Ekici, Arif B.; Marx, Lena M.; Suresh, Neeraja Puliparambil; Frischknecht, Renato; Fejtova, Anna; Saied, Essa M.; Arenz, Christoph; Bozec, Aline; Wank, Isabel; Kreitz, Silke; Hess, Andreas; Bäuerle, Tobias; Ledesma, Maria Dolores; Mitroi, Daniel N.; Miranda, André M.; Oliveira, Tiago G.; Gulbins, Erich; Lenz, Bernd; Schumann, Gunter; Kornhuber, Johannes; Müller, Christian P.
    Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects
    In: Molecular Psychiatry Jg. 26 (2021) Nr. 12, S. 7403 - 7416
    Online Volltext: dx.doi.org/ (Open Access)
  • Kornhuber, Johannes; Gulbins, Erich
    New Molecular Targets for Antidepressant Drugs
    In: Pharmaceuticals Jg. 14 (2021) Nr. 9, 894
    Online Volltext: dx.doi.org/ (Open Access)
  • Ousingsawat, Jiraporn; Schreiber, Rainer; Gulbins, Erich; Kamler, Markus; Kunzelmann, Karl
    P. aeruginosa induced lipid peroxidation causes ferroptotic cell death in airways
    In: Cellular Physiology and Biochemistry Jg. 55 (2021) Nr. 5, S. 590 - 604
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoertel, Nicolas; Sánchez-Rico, Marina; Cougoule, Céline; Gulbins, Erich; Kornhuber, Johannes; Carpinteiro, Alexander; Becker, Katrin Anne; Reiersen, Angela M.; Lenze, Eric J.; Seftel, David; Lemogne, Cédric; Limosin, Frédéric
    Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19 : Current evidence and potential mechanisms
    In: Molecular Psychiatry Jg. 26 (2021) Nr. 12, S. 7098 - 7099
    Online Volltext: dx.doi.org/ (Open Access)
  • Krones, David; Rühling, Marcel; Becker, Katrin Anne; Kunz, Tobias C.; Sehl, Carolin; Paprotka, Kerstin; Gulbins, Erich; Fraunholz, Martin
    Staphylococcus aureus α-Toxin Induces Acid Sphingomyelinase Release From a Human Endothelial Cell Line
    In: Frontiers in Microbiology Jg. 12 (2021) 694489
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Yuqing; Liu, Yongjie; Gulbins, Erich; Grassmé, Heike
    The Anti-Infectious Role of Sphingosine in Microbial Diseases
    In: Cells Jg. 10 (2021) Nr. 5, 1105
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Niziolek, Grace M.; Hoehn, Richard S.; Seitz, Aaron P.; Jernigan, Peter L.; Makley, Amy T.; Gulbins, Erich; Edwards, Michael J.; Goodman, Michael D.
    The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury
    In: Journal of Surgical Research Jg. 259 (2021) S. 296 - 304
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wu, Yuqing; Li, Cao; Peng, Huiming; Swaidan, Ashraf; Riehle, Andrea; Pollmeier, Barbara; Zhang, Yang; Gulbins, Erich; Grassmé, Heike
    Acid Sphingomyelinase Contributes to the Control of Mycobacterial Infection via a Signaling Cascade Leading from Reactive Oxygen Species to Cathepsin D
    In: Cells Jg. 9 (2020) Nr. 11, S. 2406
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Niziolek, Grace M.; Boudreau, Ryan M.; Baker, Jennifer; Friend, Lou Ann; Makley, Amy T.; Edwards, Michael J.; Gulbins, Erich; Goodman, Michael D.
    Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain Injury
    In: Journal of Neurotrauma Jg. 37 (2020) Nr. 17, S. 1902 - 1909
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lang, Judith; Bohn, Patrick; Bhat, Hilal; Jastrow, Holger; Walkenfort, Bernd; Cansiz, Feyza; Fink, Julian; Bauer, Michael; Olszewski, Dominik; Ramos-Nascimento, Ana; Duhan, Vikas; Friedrich, Sarah-Kim; Becker-Flegler, Katrin; Krawczyk, Adalbert; Edwards, Michael J.; Burchert, Andreas; Huber, Magdalena; Friebus-Kardash, Justa; Göthert, Joachim Rudolf; Hardt, Cornelia; Probst, Hans Christian; Schumacher, Fabian; Köhrer, Karl; Kleuser, Burkhard; Babiychuk, Eduard B.; Sodeik, Beate; Seibel, Jürgen; Greber, Urs F.; Lang, Philipp A.; Gulbins, Erich; Lang, Karl S.
    Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
    In: Nature Communications Jg. 11 (2020) Nr. 1, S. 1338
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Böll, Svenja; Ziemann, Sebastian; Ohl, Kim; Klemm, Patricia; Rieg, Annette D.; Gulbins, Erich; Becker, Katrin; Kamler, Markus; Wagner, Norbert; Uhlig, Stefan; Martin, Christian; Tenbrock, Klaus; Verjans, Eva
    Acid sphingomyelinase regulates TH2 cytokine release and bronchial asthma
    In: Allergy Jg. 75 (2020) Nr. 3, S. 603 - 615
    Online Volltext: dx.doi.org/ (Open Access)
  • Zoicas, Iulia; Mühle, Christiane; Schmidtner, Anna K.; Gulbins, Erich; Neumann, Inga D.; Kornhuber, Johannes
    Anxiety and Depression Are Related to Higher Activity of Sphingolipid Metabolizing Enzymes in the Rat Brain
    In: Cells Jg. 9 (2020) Nr. 5, S. 1239
    Online Volltext: dx.doi.org/ (Open Access)
  • Bhat, Owais M.; Li, Guangbi; Yuan, Xinxu; Huang, Dandan; Gulbins, Erich; Kukreja, Rakesh C.; Li, Pin-Lan
    Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice
    In: Scientific Reports Jg. 10 (2020) Nr. 1, S. 1645
    Online Volltext: dx.doi.org/ (Open Access)
  • Zoicas, Iulia; Huber, Sabine E.; Kalinichenko, Liubov S.; Gulbins, Erich; Müller, Christian P.; Kornhuber, Johannes
    Ceramides affect alcohol consumption and depressive-like and anxiety-like behavior in a brain region- and ceramide species-specific way in male mice
    In: Addiction Biology Jg. 25 (2020) Nr. 6, S. e12847
    Online Volltext: dx.doi.org/ (Open Access)
  • Naser, Eyad; Kadow, Stephanie; Schumacher, Fabian; Mohamed, Zainelabdeen H.; Kappe, Christian; Hessler, Gabriele; Pollmeier, Barbara; Kleuser, Burkhard; Arenz, Christoph; Becker, Katrin Anne; Gulbins, Erich; Carpinteiro, Alexander
    Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro
    In: Journal of Lipid Research Jg. 61 (2020) Nr. 6, S. 896 - 910
    Online Volltext: dx.doi.org/ (Open Access)
  • Baker, Jennifer E.; Seitz, Aaron P.; Boudreau, Ryan M.; Skinner, Mitchell J.; Beydoun, Ahmed; Kaval, Necati; Caldwell, Charles C.; Gulbins, Erich; Edwards, Michael J.; Gobble, Ryan M.
    Doxycycline-coated silicone breast implants reduce acute surgical-site infection and inflammation
    In: Plastic and Reconstructive Surgery Jg. 146 (2020) Nr. 5, S. 1029 - 1041
    Online Volltext: dx.doi.org/
  • Hagemann, Nina; Mohamud Yusuf, Ayan; Martiny, Carlotta; Zhang, Xiaoni; Kleinschnitz, Christoph; Gunzer, Matthias; Kolesnick, Richard; Gulbins, Erich; Hermann, Dirk M.
    Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia
    In: Basic Research in Cardiology Jg. 115 (2020) Nr. 6, S. 64
    Online Volltext: dx.doi.org/ (Open Access)
  • Yuan, Xinxu; Bhat, Owais M.; Camus, Sarah; Zhang, Yang; Gulbins, Erich; Li, Pin-Lan
    Importance of Acid Sphingomyelinase in Subendothelial Accumulation of Exosomes and Inflammatory Response in Mouse Carotid Arteries
    In: The FASEB Journal Jg. 34 (2020) Nr. S1,
    Online Volltext: dx.doi.org/ (Open Access)
  • Peruzzo, Roberta; Mattarei, Andrea; Azzolini, Michele; Becker-Flegler, Katrin; Romio, Matteo; Rigoni, Giovanni; Carrer, Andrea; Biasutto, Lucia; Parrasia, Sofia; Kadow, Stephanie; Managò, Antonella; Urbani, Andrea; Rossa, Andrea; Semenzato, Gianpietro; Soriano, Maria Eugenia; Trentin, Livio; Ahmad, Syed; Edwards, Michael; Gulbins, Erich; Paradisi, Cristina; Zoratti, Mario; Leanza, Luigi; Szabò, Ildikò
    Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
    In: Redox Biology Jg. 37 (2020) 101705
    Online Volltext: dx.doi.org/ (Open Access)
  • Carpinteiro, Alexander; Edwards, Michael J.; Hoffmann, Markus; Kochs, Georg; Gripp, Barbara; Weigang, Sebastian; Adams, Constantin; Carpinteiro, Elisa; Gulbins, Anne; Keitsch, Simone; Sehl, Carolin; Soddemann, Matthias; Wilker, Barbara; Kamler, Markus; Bertsch, Thomas; Lang, Karl S.; Patel, Sameer; Wilson, Gregory C.; Walter, Silke; Hengel, Hartmut; Pöhlmann, Stefan; Lang, Philipp A.; Kornhuber, Johannes; Becker, Katrin; Ahmad, Syed A.; Fassbender, Klaus; Gulbins, Erich
    Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells
    In: Cell Reports Medicine Jg. 1 (2020) Nr. 8, S. 100142
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Guangbi; Kidd, Jason; Kaspar, Cristin; Dempsey, Sara; Bhat, Owais M.; Camus, Sarah; Ritter, Joseph K.; Gehr, Todd W.B.; Gulbins, Erich; Li, Pin-Lan
    Podocytopathy and Nephrotic Syndrome in Mice with Podocyte-Specific Deletion of the Asah1 Gene : Role of Ceramide Accumulation in Glomeruli
    In: The American Journal of Pathology Jg. 190 (2020) Nr. 6, S. 1211 - 1223
    Online Volltext: dx.doi.org/ (Open Access)
  • Gardner, Aaron I.; Haq, Iram J.; Simpson, A. John; Becker, Katrin; Gallagher, John; Saint-Criq, Vinciane; Verdon, Bernard; Mavin, Emily; Trigg, Alexandra; Gray, Michael A.; Koulman, Albert; McDonnell, Melissa J.; Fisher, Andrew J.; Kramer, Elizabeth L.; Clancy, John P.; Ward, Christopher; Schuchman, Edward H.; Gulbins, Erich; Brodlie, Malcolm
    Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis
    In: American Journal of Respiratory and Critical Care Medicine (AJRCCM) Jg. 202 (2020) Nr. 8, S. 1133 - 1145
    Online Volltext: dx.doi.org/ (Open Access)
  • Becker, Katrin; Uerschels, Anne-Kathrin; Goins, Laura; Doolen, Suzanne; McQuerry, Kristen J.; Bielawski, Jacek; Sure, Ulrich; Bieberich, Erhard; Taylor, Bradley K.; Gulbins, Erich; Spassieva, Stefka D.
    Role of 1-Deoxysphingolipids in docetaxel neurotoxicity
    In: Journal of Neurochemistry Jg. 154 (2020) Nr. 6,
    Online Volltext: dx.doi.org/ (Open Access)
  • Kalinichenko, Liubov S.; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P.
    Serotonin – lipid interactions and their role in behavior
    In: Handbook of Behavioral Neuroscience Jg. 31 (2020) S. 289 - 308
    Online Volltext: dx.doi.org/
  • Beck, Sascha; Sehl, Carolin; Voortmann, Sylvia; Verhasselt, Hedda Luise; Edwards, Michael J.; Buer, Jan; Hasenberg, Mike; Gulbins, Erich; Becker-Flegler, Katrin
    Sphingosine is able to prevent and eliminate Staphylococcus epidermidis biofilm formation on different orthopedic implant materials in vitro
    In: Journal of Molecular Medicine Jg. 98 (2020) Nr. 2, S. 209 - 219
    Online Volltext: dx.doi.org/ (Open Access)
  • Verhaegh, Rabea; Becker, Katrin Anne; Edwards, Michael J.; Gulbins, Erich
    Sphingosine kills bacteria by binding to cardiolipin
    In: The Journal of Biological Chemistry (JBC) Jg. 295 (2020) Nr. 22, S. 7686 - 7696
    Online Volltext: dx.doi.org/ (Open Access)
  • Edwards, Michael J.; Becker, Katrin; Gripp, Barbara; Hoffmann, Markus; Keitsch, Simone; Wilker, Barbara; Soddemann, Matthias; Gulbins, Anne; Carpinteiro, Elisa; Patel, Sameer H.; Wilson, Gregory C.; Pöhlmann, Stefan; Walter, Silke; Fassbender, Klaus; Ahmad, Syed A.; Carpinteiro, Alexander; Gulbins, Erich
    Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2
    In: The Journal of Biological Chemistry (JBC) Jg. 295 (2020) Nr. 45, S. 15174 - 15182
    Online Volltext: dx.doi.org/ (Open Access)
  • Zoicas, Iulia; Schumacher, Fabian; Kleuser, Burkhard; Reichel, Martin; Gulbins, Erich; Fejtova, Anna; Kornhuber, Johannes; Rhein, Cosima
    The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice
    In: Cells Jg. 9 (2020) Nr. 5, S. 1244
    Online Volltext: dx.doi.org/ (Open Access)
  • Beckmann, Nadine; Pugh, Amanda M.; Auteri, Nicholas J.; Edwards, Michael J.; Gulbins, Erich; Caldwell, Charles C.
    Therapeutic Inhaled Sphingosine for Treating Lung Infection in a Mouse Model of Critical Illness
    In: Cellular Physiology and Biochemistry Jg. 54 (2020) Nr. 5, S. 1054 - 1067
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Herbstreit, Frank; Carpinteiro, Alexander; Baum, Julia; Tzalavras, Asterios; Aramayo-Singelmann, Carmen; Vance, Colin; Lenz, Veronika; Gulbins, Erich; Reinhardt, Dirk; Beelen, Dietrich; Dührsen, Ulrich; Röth, Alexander; Koldehoff, Michael; Liebregts, Tobias
    Veno-Venous Extracorporeal Membrane Oxygenation in Adult Patients with Sickle Cell Disease and Acute Chest Syndrome : a Single-Center Experience
    In: Hemoglobin Jg. 44 (2020) Nr. 2, S. 71 - 77
    Online Volltext: dx.doi.org/
  • Bachmann, Magdalena; Li, Weiwei; Edwards, Michael J.; Ahmad, Syed A.; Patel, Sameer; Szabo, Ildiko; Gulbins, Erich
    Voltage-Gated Potassium Channels as Regulators of Cell Death
    In: Frontiers in Cell and Developmental Biology Jg. 8 (2020) 611853
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Cao; Wang, Anni; Wu, Yuqing; Gulbins, Erich; Grassmé, Heike; Zhao, Zhigang
    Acid Sphingomyelinase-Ceramide System in Bacterial Infections
    In: Cellular Physiology and Biochemistry Jg. 52 (2019) Nr. 2, S. 280 - 301
    Online Volltext: dx.doi.org/ (Open Access)
  • Kalinichenko, Liubov S.; Hammad, Lara; Reichel, Martin; Kohl, Zacharias; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P.
    Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice
    In: Brain Research Bulletin Jg. 146 (2019) S. 310 - 319
    Online Volltext: dx.doi.org/
  • Beckmann, Nadine; Becker, Katrin Anne; Kadow, Stephanie; Schumacher, Fabian; Kramer, Melanie; Kühn, Claudine; Schulz-Schaeffer, Walter J.; Edwards, Michael J.; Kleuser, Burkhard; Gulbins, Erich; Carpinteiro, Alexander
    Acid sphingomyelinase deficiency ameliorates farber disease
    In: International Journal of Molecular Sciences (IJMS) Jg. 20 (2019) Nr. 24, S. 6253
    Online Volltext: dx.doi.org/ (Open Access)
  • Xia, Brent T.; Beckmann, Nadine; Winer, Leah K.; Pugh, Amanda M.; Pritts, Timothy A; Nomellini, Vanessa; Gulbins, Erich; Caldwell, Charles C
    Amitriptyline Reduces Inflammation and Mortality in a Murine Model of Sepsis.
    In: Cellular Physiology and Biochemistry Jg. 52 (2019) Nr. 3, S. 565 - 579
    Online Volltext: dx.doi.org/ (Open Access)
  • Xia, Brent T.; Beckmann, Nadine; Winer, Leah K.; Kim, Young; Goetzman, Holly S.; Veile, Rosalie E.; Gulbins, Erich; Goodman, Michael D.; Nomellini, Vanessa; Caldwell, Charles C.
    Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy
    In: Shock Jg. 51 (2019) Nr. 3, S. 356 - 363
    Online Volltext: dx.doi.org/ (Open Access)
  • Bodas, Manish; Pehote, Garrett; Silverberg, David; Gulbins, Erich; Vij, Neeraj
    Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis
    In: Free Radical Biology and Medicine Jg. 131 (2019) S. 81 - 97
    Online Volltext: dx.doi.org/
  • Carstens, Henning; Schumacher, Fabian; Keitsch, Simone; Kramer, Melanie; Kühn, Claudine; Sehl, Carolin; Soddemann, Matthias; Wilker, Barbara; Herrmann, Daniel; Swaidan, Ashraf; Kleuser, Burkhard; Verhaegh, Rabea; Hilken, Gero; Edwards, Michael J.; Dubicanac, Marko; Carpinteiro, Alexander; Wißmann, Andreas; Becker-Flegler, Katrin; Kamler, Markus; Gulbins, Erich
    Clinical development of sphingosine as anti-bacterial drug : Inhalation of sphingosine in mini pigs has no adverse side effects
    In: Cellular Physiology and Biochemistry Jg. 53 (2019) Nr. 6, S. 1015 - 1028
    Online Volltext: dx.doi.org/ (Open Access)
  • Kalinichenko, Liubov S.; Mühle, Christiane; Eulenburg, Volker; Praetner, Marc; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P.
    Enhanced alcohol preference and anxiolytic alcohol effects in Niemann-Pick disease model in mice
    In: Frontiers in Neurology Jg. 10 (2019) Nr. JUL, S. 731
    Online Volltext: dx.doi.org/ (Open Access)
  • Wigger, Dominik; Gulbins, Erich; Kleuser, Burkhard; Schumacher, Fabian
    Monitoring the sphingolipid de novo synthesis by stable-isotope labeling and liquid chromatography-mass spectrometry
    In: Frontiers in Cell and Developmental Biology Jg. 7 (2019) 210
    Online Volltext: dx.doi.org/ (Open Access)
  • Walter, Silke; Gulbins, Erich; Halmer, Ramona; Jahromi, Neda Haghayegh; Becker-Flegler, Katrin; Schottek, Andrea; Blatti, Claudia; Davies, Laura; Schnoeder, Laura; Bertsch, Thomas; Engelhardt, Britta; Fassbender, Klaus
    Pharmacological Inhibition of Acid Sphingomyelinase Ameliorates Experimental Autoimmune Encephalomyelitis
    In: Neurosignals Jg. 27 (2019) Nr. S1, S. 20 - 31
    Online Volltext: dx.doi.org/ (Open Access)
  • Mühle, Christiane; Wagner, Claudia Johanna; Färber, Katharina; Richter-Schmidinger, Tanja; Gulbins, Erich; Lenz, Bernd; Kornhuber, Johannes
    Secretory Acid Sphingomyelinase in the Serum of Medicated Patients Predicts the Prospective Course of Depression
    In: Journal of Clinical Medicine (JCM) Jg. 8 (2019) Nr. 6, 846
    Online Volltext: dx.doi.org/ (Open Access)
  • Baduva, Käthe; Büchter, Lara; Kreyenkamp, Katja; Westphal, Linnea; Wilker, Barbara; Kohnen, Marcus; Schuchman, Edward H.; Edwards, Michael J.; Becker, Katrin Anne; Gulbins, Erich; Carpinteiro, Alexander
    Signalling Effects Induced by Acid Ceramidase in Human Epithelial Or Leukemic Cell Lines
    In: Cellular Physiology and Biochemistry Jg. 52 (2019) Nr. 5, S. 1092 - 1102
    Online Volltext: dx.doi.org/ (Open Access)
  • McElvaney, Oliver J.; Zaslona, Zbigniew; Becker-Flegler, Katrin; Palsson-McDermott, Eva M.; Boland, Fiona; Gunaratnam, Cedric; Gulbins, Erich; O'Neill, Luke A.; Reeves, Emer P.; McElvaney, Noel G.
    Specific inhibition of the NLRP3 inflammasome as an antiinflammatory strategy in cystic fibrosis
    In: American Journal of Respiratory and Critical Care Medicine (AJRCCM) Jg. 200 (2019) Nr. 11, S. 1381 - 1391
    Online Volltext: dx.doi.org/
  • Seitz, Aaron P.; Schumacher, Fabian; Baker, Jennifer; Soddemann, Matthias; Wilker, Barbara; Caldwell, Charles C.; Gobble, Ryan M.; Kamler, Markus; Becker-Flegler, Katrin; Beck, Sascha; Kleuser, Burkhard; Edwards, Michael J.; Gulbins, Erich
    Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia
    In: Journal of Molecular Medicine Jg. 97 (2019) Nr. 8, S. 1195 - 1211
    Online Volltext: dx.doi.org/ (Open Access)
  • Morris, Mackenzie C.; Kassam, Farzaan; Bercz, Aron; Beckmann, Nadine; Schumacher, Fabian; Gulbins, Erich; Makley, A.T.; Goodman, Michael D.
    The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury
    In: Journal of Surgical Research Jg. 244 (2019) S. 1 - 8
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Gulbins, Anne; Schumacher, Fabian; Becker, Katrin Anne; Wilker, Barbara; Soddemann, Matthias; Boldrin, Francesco; Müller, Christian P.; Edwards, Michael J.; Goodman, Michael; Caldwell, Charles C.; Kleuser, Burkhard; Kornhuber, Johannes; Szabo, Ildiko; Gulbins, Erich
    Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide
    In: Molecular Psychiatry Jg. 23 (2018) Nr. 12, S. 2324 - 2346
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Anne; Schumacher, Fabian; Becker, Katrin Anne; Wilker, Barbara; Soddemann, Matthias; Boldrin, Francesco; Müller, Christian P.; Edwards, Michael J.; Goodman, Michael; Caldwell, Charles C.; Kleuser, Burkhard; Kornhuber, Johannes; Szabo, Ildiko; Gulbins, Erich
    Antidepressants regulate autophagy by targeting acid sphingomyelinase
    In: Molecular Psychiatry Jg. 23 (2018) Nr. 12, S. 2251
    Online Volltext: dx.doi.org/
  • Li, Pin-Lan; Gulbins, Erich
    Bioactive lipids and redox signaling: Molecular mechanism and disease pathogenesis
    In: Antioxidants and Redox Signaling Jg. 28 (2018) Nr. 10, S. 911 - 915
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Becker-Flegler, Katrin; Halmer, Ramona; Davies, Laura; Henry, Brian D.; Ziobro-Henry, Regan; Decker, Yann; Liu, Yang; Gulbins, Erich; Fassbender, Klaus; Walter, Silke
    Blockade of experimental multiple sclerosis by inhibition of the acid sphingomyelinase/ceramide system
    In: Neurosignals Jg. 25 (2018) Nr. 1, S. 88 - 97
    Online Volltext: dx.doi.org/ (Open Access)
  • Reichel, Martin; Rhein, Cosima; Hofmann, Lena M.; Monti, Juliana; Japtok, Lukasz; Langgartner, Dominik; Füchsl, Andrea M.; Kleuser, Burkhard; Gulbins, Erich; Hellerbrand, Claus; Reber, Stefan O.; Kornhuber, Johannes
    Chronic psychosocial stress in mice is associated with increased acid sphingomyelinase activity in liver and serum and with hepatic C16:0-ceramide accumulation
    In: Frontiers in Psychiatry Jg. 9 (2018) S. 496
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Yuqing; Gulbins, Erich; Grassmé, Heike
    Crosstalk between sphingomyelinases and reactive oxygen species in mycobacterial infection
    In: Antioxidants and Redox Signaling Jg. 28 (2018) Nr. 10, S. 935 - 948
    Online Volltext: dx.doi.org/
  • Rhein, Cosima; Löber, Stefan; Gmeiner, Peter; Gulbins, Erich; Tripal, Philipp; Kornhuber, Johannes
    Derivatization of common antidepressant drugs increases inhibition of acid sphingomyelinase and reduces induction of phospholipidosis
    In: Journal of Neural Transmission Jg. 125 (2018) Nr. 12, S. 1837 - 1845
    Online Volltext: dx.doi.org/
  • Gobble, Ryan M.; Gulbins, Erich; Seitz, Aaron P.; Boudreau, Ryan M.; Baker, Jennifer E.; Edwards, Michael
    Doxycycline-Coated Silicone Breast Implant Reduces Surgical Site Infections Compared with Standard Gentamycin/Cefazolin/Bacitracin Wash
    In: Journal of the American College of Surgeons Jg. 227 (2018) Nr. Suppl. 1, S. S206 - S207
    Online Volltext: dx.doi.org/
  • Kim, Young; Abplanalp, William A.; Jung, Andrew D.; Schuster, Rebecca M.; Lentsch, Alex B.; Gulbins, Erich; Caldwell, Charles C.; Pritts, Timothy A.
    Endocytosis of red blood cell microparticles by pulmonary endothelial cells is mediated by Rab5
    In: Shock Jg. 49 (2018) Nr. 3, S. 288 - 294
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Carpinteiro, Alexander; Becker-Flegler, Katrin; Gulbins, Erich
    Highlight : Sphingolipids in infectious biology and immunology
    In: Biological Chemistry Jg. 399 (2018) Nr. 10, S. 1113 - 1113
    Online Volltext: dx.doi.org/
  • Wu, Yuqing; Li, Cao; Riehle, Andrea; Pollmeier, Barbara; Gulbins, Erich; Grassmé, Heike
    Mycobacterial Infection is Promoted by Neutral Sphingomyelinase 2 Regulating a Signaling Cascade Leading to Activation of β1-Integrin
    In: Cellular Physiology and Biochemistry Jg. 51 (2018) Nr. 4, S. 1815 - 1829
    Online Volltext: dx.doi.org/ (Open Access)
  • Beckmann, Nadine; Kadow, Stephanie; Schumacher, Fabian; Göthert, Joachim Rudolf; Kesper, Stefanie; Draeger, Annette; Schulz-Schaeffer, Walter J.; Wang, Jiang; Becker, Jan U.; Kramer, Melanie; Kühn, Claudine; Kleuser, Burkhard; Becker-Flegler, Katrin; Gulbins, Erich; Carpinteiro, Alexander
    Pathological manifestations of Farber disease in a new mouse model
    In: Biological Chemistry Jg. 399 (2018) Nr. 10, S. 1183 - 1202
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mühle, Christiane; Weinland, Christian; Gulbins, Erich; Lenz, Bernd; Kornhuber, Johannes
    Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls
    In: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 12, S. 4028
    Online Volltext: dx.doi.org/ (Open Access)
  • Keitsch, Simone; Riethmüller, Joachim; Soddemann, Matthias; Sehl, Carolin; Wilker, Barbara; Edwards, Michael J.; Caldwell, Charles C.; Fraunholz, Martin; Gulbins, Erich; Becker-Flegler, Katrin
    Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of α-toxin
    In: Biological Chemistry Jg. 399 (2018) Nr. 10, S. 1203 - 1213
    Online Volltext: dx.doi.org/
  • Li, Cao; Wu, Yuqing; Riehle, Andrea; Orian-Rousseau, Véronique; Zhang, Yang; Gulbins, Erich; Grassmé, Heike
    Regulation of Staphylococcus aureus Infection of Macrophages by CD44, Reactive Oxygen Species, and Acid Sphingomyelinase
    In: Antioxidants and Redox Signaling Jg. 28 (2018) Nr. 10, S. 916 - 934
    Online Volltext: dx.doi.org/ (Open Access)
  • Baker, Jennifer E.; Boudreau, Ryan M.; Seitz, Aaron P.; Caldwell, Charles C.; Gulbins, Erich; Edwards, Michael J.
    Sphingolipids and innate immunity : a new approach to infection in the post-antibiotic era?
    In: Surgical Infections Jg. 19 (2018) Nr. 8, S. 792 - 803
    Online Volltext: dx.doi.org/
  • Becker-Flegler, Katrin; Riethmüller, Joachim; Seitz, Aaron P.; Gardner, Aaron; Boudreau, Ryan; Kamler, Markus; Kleuser, Burkhard; Schuchman, Edward; Caldwell, Charles C.; Edwards, Michael J.; Grassmé, Heike; Brodlie, Malcolm; Gulbins, Erich
    Sphingolipids as targets for inhalation treatment of cystic fibrosis
    In: Advanced Drug Delivery Reviews Jg. 133 (2018) S. 66 - 75
    Online Volltext: dx.doi.org/
  • Bezgovsek, Judith; Gulbins, Erich; Friedrich, Sarah-Kim; Lang, Karl S.; Duhan, Vikas
    Sphingolipids in early viral replication and innate immune activation
    In: Biological Chemistry Jg. 399 (2018) Nr. 10, S. 1115 - 1123
    Online Volltext: dx.doi.org/
  • Becker-Flegler, Katrin; Fahsel, Björn; Kemper, Hannes; Mayeres, Joelina; Li, Cao; Wilker, Barbara; Keitsch, Simone; Soddemann, Matthias; Sehl, Carolin; Kohnen, Marcus; Edwards, Michael J.; Grassmé, Heike; Caldwell, Charles C.; Seitz, Aaron; Fraunholz, Martin; Gulbins, Erich
    Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinase and ceramide
    In: Infection and Immunity Jg. 86 (2018) Nr. 1, S. e00606 - 17
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Venturini, Elisa; Leanza, Luigi; Azzolini, Michele; Kadow, Stephanie; Mattarei, Andrea; Weller, Michael; Tabatabai, Ghazaleh; Edwards, Michael J.; Zoratti, Mario; Paradisi, Cristina; Szabò, Ildikò; Gulbins, Erich; Becker-Flegler, Katrin
    Targeting the potassium channel Kv1.3 kills glioblastoma cells
    In: Neurosignals Jg. 25 (2018) Nr. 1, S. 26 - 38
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Yuqing; Gulbins, Erich; Grassmé, Heike
    The function of sphingomyelinases in mycobacterial infections
    In: Biological Chemistry Jg. 399 (2018) Nr. 10, S. 1125 - 1133
    Online Volltext: dx.doi.org/
  • Kalinichenko, Liubov S.; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P.
    The role of sphingolipids in psychoactive drug use and addiction
    In: Journal of Neural Transmission Jg. 125 (2018) Nr. 4, S. 651 - 672
    Online Volltext: dx.doi.org/
  • Park, Min Hee; Lee, Ju Youn; Park, Kang Ho; Jung, In Kyung; Kim, Kyoung-Tae; Lee, Yong-Seok; Ryu, Hyun-Hee; Jeong, Yong; Kang, Minseok; Schwaninger, Markus; Gulbins, Erich; Reichel, Martin; Kornhuber, Johannes; Yamaguchi, Tomoyuki; Kim, Hee-Jin; Kim, Seung Hyun; Schuchman, Edward H; Jin, Hee Kyung; Bae, Jae-Sung
    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
    In: Neuron Jg. 100 (2018) Nr. 3, S. 762
    Online Volltext: dx.doi.org/ (Open Access)
  • Park, Min Hee; Lee, Ju Youn; Park, Kang Ho; Jung, In Kyung; Kim, Kyoung-Tae; Lee, Yong-Seok; Ryu, Hyun-Hee; Jeong, Yong; Kang, Minseok; Schwaninger, Markus; Gulbins, Erich; Reichel, Martin; Kornhuber, Johannes; Yamaguchi, Tomoyuki; Kim, Hee-Jin; Kim, Seung Hyun; Schuchman, Edward H.; Jin, Hee Kyung; Bae, Jae-Sung
    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
    In: Neuron Jg. 100 (2018) Nr. 1, S. 167 - 182.e9
    Online Volltext: dx.doi.org/ (Open Access)
  • Seitz, Aaraon; Martin, Grace; Gulbins, Erich; Edwards, Michael; Boudreau, Ryan M.; Goodman, Michael D.; Hoehn, Richard S.
    Acid Sphingomyelinase Inhibition Reduces the Harmful Effects of Repetitive Mild Traumatic Brain Injury
    In: Journal of the American College of Surgeons Jg. 225 (2017) Nr. 4, Suppl. 2, S. e174
    Online Volltext: dx.doi.org/
  • Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A
    Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation
    In: Annals of Surgery Jg. 265 (2017) Nr. 1, S. 218 - 226
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Chami, Marwan; Halmer, Ramona; Schnoeder, Laura; Becker, Katrin Anne; Meier, Carola; Fassbender, Klaus; Gulbins, Erich; Walter, Silke
    Acid sphingomyelinase deficiency enhances myelin repair after acute and chronic demyelination
    In: PLoS ONE Jg. 12 (2017) Nr. 6, S. e0178622
    Online Volltext: dx.doi.org/ (Open Access)
  • Sydor, Svenja; Sowa, Jan-Peter; Megger, Dominik A.; Schlattjan, Martin; Jafoui, Sami; Wingerter, Lena; Carpinteiro, Alexander; Baba, Hideo Andreas; Bechmann, Lars Peter; Sitek, Barbara; Gerken, Guido; Gulbins, Erich; Canbay, Aliekber
    Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis
    In: Molecular Metabolism Jg. 6 (2017) Nr. 5, S. 416 - 427
    Online Volltext: dx.doi.org/ (Open Access)
  • Rhein, Cosima; Reichel, Martin; Kramer, Marcel; Rotter, Andrea; Lenz, Bernd; Mühle, Christiane; Gulbins, Erich; Kornhuber, Johannes
    Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression
    In: Journal of Affective Disorders Jg. 209 (2017) S. 10 - 15
    Online Volltext: dx.doi.org/
  • Xia, B. T.; Goetzman, H. S.; Pritts, T. A.; Gulbins, Erich; Caldwell, C. C.
    Amitriptyline treatment ameliorates septic shock and improves survival
    In: Shock Jg. 47 1 (2017) Nr. 6, S. 91 - 91
  • Xia, B. T.; Gulbins, Erich; Goodman, M. D.; Caldwell, C. C.
    Amitriptyline treatment prvents the coagulopathy of sepsis
    In: Shock Jg. 47 (2017) Nr. 6 Suppl.1, S. 46 - 47
  • Rice, Teresa C.; Pugh, Amanda M.; Xia, Brent T.; Seitz, Aaron P.; Whitacre, Brynne E.; Gulbins, Erich; Caldwell, Charles C.
    Bronchoalveolar Lavage Microvesicles Protect Burn-Injured Mice from Pulmonary Infection
    In: Journal of the American College of Surgeons Jg. 225 (2017) Nr. 4, S. 538 - 547
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rice, Teresa C.; Armocida, Stephanie M.; Kuethe, Joshua W.; Midura, Emily F.; Jain, Ayushi; Hildeman, David A.; Healy, Daniel P.; Gulbins, Erich; Caldwell, Charles C.
    Burn injury influences the T cell homeostasis in a butyrate-acid sphingomyelinase dependent manner
    In: Cellular Immunology Jg. 313 (2017) S. 25 - 31
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bao, Junxiang; Li, Guangbi; Yuan, Xinxu; Li, Pin-Lan; Gulbins, Erich
    Contribution of p62 to Phenotype Transition of Coronary Arterial Myocytes with Defective Autophagy
    In: Cellular Physiology and Biochemistry Jg. 41 (2017) Nr. 2, S. 555 - 568
    Online Volltext: dx.doi.org/ (Open Access)
  • Leanza, L.; Azzolini, M.; Biasutto, L.; Severin, F.; Martini, V.; Trentin, L.; Mattarei, A.; Zoratti, M.; Paradisi, C.; Gulbins, Erich; Szabo, I.
    Direct pharmacological targeting of a mitochondrial ion channel eliminates cancer cells in vivo
    In: European Biophysics Journal Jg. 46 (2017) Nr. Suppl. 1, S. 77 - S77
  • Leanza, Luigi; Romio, Matteo; Becker-Flegler, Katrin; Azzolini, Michele; Trentin, Livio; Managò, Antonella; Venturini, Elisa; Zaccagnino, Angela; Mattarei, Andrea; Carraretto, Luca; Urbani, Andrea; Kadow, Stephanie; Biasutto, Lucia; Martini, Veronica; Severin, Filippo; Peruzzo, Roberta; Trimarco, Valentina; Egberts, Jan-Hendrik; Hauser, Charlotte; Visentin, Andrea; Semenzato, Gianpietro; Kalthoff, Holger; Zoratti, Mario; Gulbins, Erich; Paradisi, Cristina; Szabo, Ildiko
    Direct pharmacological targeting of a mitochondrial ion channel selectively kills tumor cells in vivo
    In: Cancer Cell Jg. 31 (2017) Nr. 4, S. 516 - 531.e10
    Online Volltext: dx.doi.org/ (Open Access)
  • Seitz, Aaron; Edwards, Michael; Gulbins, Erich; Martin, Grace; Boudreau, Ryan M.; Gobble, Ryan M.; Caldwell, Charles C.
    Doxycycline Impregnated Silicone Implants Are a Novel Strategy to Reduce Incidence of Breast Implant Infection
    In: Journal of the American College of Surgeons Jg. 225 (2017) Nr. 4, Suppl. 1, S. S162
    Online Volltext: dx.doi.org/
  • Kim, Y.; Abplanalp, W. A.; Jung, A. D.; Schuster, R. M.; Lentsch, A. B.; Gulbins, Erich; Caldwell, C. C.; Pritts, T. A.
    Endocytosis of red blood cell microparticels by endothelial cells is mediated by RAB5
    In: Shock Jg. 47 (2017) Nr. 6 Suppl. 1, S. 14 - 14
  • Item, Flurin; Wueest, Stephan; Lemos, Vera; Stein, Sokrates; Lucchini, Fabrizio C.; Denzler, Rémy; Fisser, Muriel C.; Challa, Tenagne D.; Pirinen, Eija; Kim, Youngsoo; Hemmi, Silvio; Gulbins, Erich; Gross, Atan; O'Reilly, Lorraine A.; Stoffel, Markus; Auwerx, Johan; Konrad, Daniel
    Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function
    In: Nature Communications Jg. 8 (2017) S. 480
    Online Volltext: dx.doi.org/ (Open Access)
  • Kovacic, Barbara; Sehl, Carolin; Wilker, Barbara; Kamler, Markus; Becker, Katrin Anne; Gulbins, Erich
    Glucosylceramide Critically Contributes to the Host Defense of Cystic Fibrosis Lungs
    In: Cellular Physiology and Biochemistry Jg. 41 (2017) Nr. 3, S. 1208 - 1218
    Online Volltext: dx.doi.org/ (Open Access)
  • Bao, Jun-Xiang; Zhang, Qin-Fang; Wang, Mi; Xia, Min; Boini, Krishna M.; Gulbins, Erich; Zhang, Yang; Li, Pin-Lan
    Implication of CD38 gene in autophagic degradation of collagen I in mouse coronary arterial myocytes
    In: Frontiers in Bioscience (FBS): Landmark Jg. 22 (2017) S. 558 - 569
  • Folkesson, Maggie; Vorkapic, Emina; Gulbins, Erich; Japtok, Lukasz; Kleuser, Burkhard; Welander, Martin; Länne, Toste; Wågsäter, Dick
    Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms
    In: Journal of Vascular Surgery Jg. 65 (2017) Nr. 4, S. 1171 - 1179.e1
    Online Volltext: dx.doi.org/ (Open Access)
  • Schneider, Miriam; Levant, Beth; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P
    Lipids in psychiatric disorders and preventive medicine
    In: Neuroscience & Biobehavioral Reviews Jg. 76 (2017) S. 336 - 362
    Online Volltext: dx.doi.org/ (Open Access)
  • Fayyaz, Susann; Japtok, Lukasz; Schumacher, Fabian; Wigger, Dominik; Schulz, Tim Julius; Haubold, Kathrin; Gulbins, Erich; Völler, Heinz; Kleuser, Burkhard
    Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA3 Receptor Subtype and is Increased in Obesity
    In: Cellular Physiology and Biochemistry Jg. 43 (2017) Nr. 2, S. 445 - 456
    Online Volltext: dx.doi.org/ (Open Access)
  • Becker-Flegler, Katrin; Beckmann, Nadine; Adams, Constantin; Hessler, Gabriele; Kramer, Melanie; Gulbins, Erich; Carpinteiro, Alexander
    Melanoma cell metastasis via P-selectin-mediated activation of acid sphingomyelinase in platelets
    In: Clinical and Experimental Metastasis Jg. 34 (2017) Nr. 1, S. 25 - 35
    Online Volltext: dx.doi.org/
  • Becker-Flegler, Katrin; Li, Xiang; Seitz, Aaron; Steinmann, Jörg; Koch, Anne; Schuchman, Edward; Kamler, Markus; Edwards, Michael J.; Caldwell, Charles C.; Gulbins, Erich
    Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine
    In: Cellular Physiology and Biochemistry Jg. 43 (2017) Nr. 4, S. 1603 - 1616
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Müller, Christian P.; Kalinichenko, Liubov S.; Tiesel, Jens; Witt, Matthias; Stöckl, Thomas; Sprenger, Eva; Fuchser, Jens; Beckmann, Janine; Praetner, Marc; Huber, Sabine E.; Amato, Davide; Mühle, Christiane; Büttner, Christian; Ekici, Arif B.; Smaga, Irena; Pomierny-Chamiolo, Lucyna; Pomierny, Bartosz; Filip, Malgorzata; Eulenburg, Volker; Gulbins, Erich; Lourdusamy, Anbarasu; Reichel, Martin; Kornhuber, Johannes
    Paradoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis
    In: Acta Neuropathologica Jg. 133 (2017) Nr. 3, S. 463 - 483
    Online Volltext: dx.doi.org/ (Open Access)
  • Beckmann, Nadine; Becker, Katrin Anne; Walter, Silke; Becker, Jan U.; Kramer, Melanie; Hessler, Gabriele; Weber, Stefanie; Göthert, Joachim Rudolf; Fassbender, Klaus; Gulbins, Erich; Carpinteiro, Alexander
    Regulation of Arthritis Severity by the Acid Sphingomyelinase
    In: Cellular Physiology and Biochemistry Jg. 43 (2017) Nr. 4, S. 1460 - 1471
    Online Volltext: dx.doi.org/ (Open Access)
  • Rice, Teresa C.; Pugh, Amanda M.; Seitz, Aaron P.; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C.
    Sphingosine rescues aged mice from pulmonary pseudomonas infection
    In: Journal of Surgical Research Jg. 219 (2017) S. 354 - 359
    Online Volltext: dx.doi.org/
  • Martin, Grace E.; Boudreau, Ryan M.; Couch, Caroline; Becker-Flegler, Katrin; Edwards, Michael J.; Caldwell, Charles C.; Gulbins, Erich; Seitz, Aaron
    Sphingosine's role in epithelial host defense : a natural antimicrobial and novel therapeutic
    In: Biochimie Jg. 141 (2017) S. 91 - 96
    Online Volltext: dx.doi.org/
  • Li, Cao; Wu, Yuqing; Riehle, Andrea; Ma, Jie; Kamler, Markus; Gulbins, Erich; Grassmé, Heike
    Staphylococcus aureus survives in cystic fibrosis macrophages, forming a reservoir for chronic pneumonia
    In: Infection and Immunity Jg. 85 (2017) Nr. 5, S. e00883-16-1 - e00883-16-11
    Online Volltext: dx.doi.org/ (Open Access)
  • Ma, Jie; Gulbins, Erich; Edwards, Michael J.; Caldwell, Charles C.; Fraunholz, Martin; Becker-Flegler, Katrin
    Staphylococcus aureus α-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides
    In: Cellular Physiology and Biochemistry Jg. 43 (2017) Nr. 6, S. 2170 - 2184
    Online Volltext: dx.doi.org/ (Open Access)
  • Schumacher, Fabian; Neuber, Corinna; Finke, Hannah; Nieschalke, Kai; Baesler, Jessica; Gulbins, Erich; Kleuser, Burkhard
    The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro
    In: Journal of Lipid Research Jg. 58 (2017) Nr. 8, S. 1648 - 1660
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Grassmé, Heike; Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Riethmüller, Joachim; Gardner, Aaron; Seitz, Aaron P.; Steinmann, Jörg; Lang, Stephan; Ward, Christopher; Schuchman, Edward H.; Caldwell, Charles C.; Kamler, Markus; Edwards, Michael J.; Brodlie, Malcolm; Gulbins, Erich
    β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections
    In: Cell Host & Microbe Jg. 21 (2017) Nr. 6, S. 707 - 718.e8
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Huston, Joseph P; Kornhuber, Johannes; Mühle, Christiane; Japtok, Lukasz; Komorowski, Mara; Mattern, Claudia; Reichel, Martin; Gulbins, Erich; Kleuser, Burkhard; Topic, Bianca; De Souza Silva, Maria A; Müller, Christian P
    A sphingolipid mechanism for behavioral extinction
    In: Journal of Neurochemistry Jg. 137 (2016) Nr. 4, S. 589 - 603
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhou, Yuetao; Salker, Madhuri S; Walker, Britta; Münzer, Patrick; Borst, Oliver; Gawaz, Meinrad; Gulbins, Erich; Singh, Yogesh; Lang, Florian
    Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 3, S. 985 - 995
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoehn, Richard S; Jernigan, Peter L; Chang, Alex L; Edwards, Michael J; Caldwell, Charles C; Gulbins, Erich; Pritts, Timothy A
    Acid Sphingomyelinase Inhibition Prevents Hemolysis During Erythrocyte Storage
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 1, S. 331 - 340
    Online Volltext: dx.doi.org/ (Open Access)
  • Johnson, Bobby L; Rice, Teresa C; Xia, Brent T; Boone, Kirsten I; Green, Ellis A; Gulbins, Erich; Caldwell, Charles C
    Amitriptyline Usage Exacerbates the Immune Suppression Following Burn Injury
    In: Shock Jg. 46 (2016) Nr. 5, S. 541 - 548
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Nojima, Hiroyuki; Konishi, Takanori; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B
    Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes
    In: PLoS ONE Jg. 11 (2016) Nr. 8, S. e0161443
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Lei; Chen, Yang; Li, Xiang; Zhang, Youzhi; Gulbins, Erich; Zhang, Yang
    Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation
    In: OncoTarget Jg. 7 (2016) Nr. 45, S. 73229 - 73241
    Online Volltext: dx.doi.org/ (Open Access)
  • Rice, Teresa C; Seitz, Aaron P; Edwards, Michael J; Gulbins, Erich; Caldwell, Charles C
    Frontline Science : Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection
    In: Journal of Leukocyte Biology (JLB) Jg. 100 (2016) Nr. 6, S. 1233 - 1237
    Online Volltext: dx.doi.org/
  • Nojima, Hiroyuki; Freeman, Christopher M.; Schuster, Rebecca M.; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J.; Gulbins, Erich; Lentsch, Alex B.
    Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate
    In: Journal of Hepatology Jg. 64 (2016) Nr. 1, S. 60 - 68
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Hollmann, Claudia; Werner, Sandra; Avota, Elita; Reuter, Dajana; Japtok, Lukasz; Kleuser, Burkhard; Gulbins, Erich; Becker-Flegler, Katrin; Schneider-Schaulies, Jürgen; Beyersdorf, Niklas
    Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells
    In: The Journal of Immunology (JI) Jg. 197 (2016) Nr. 8, S. 3130 - 3141
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Cao; Peng, Huiming; Japtok, Lukasz; Seitz, Aaron; Riehle, Andrea; Wilker, Barbara; Soddemann, Matthias; Kleuser, Burkard; Edwards, Michael; Lammas, David; Zhang, Yang; Gulbins, Erich; Grassme, Heike
    Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis
    In: Frontiers in Bioscience Jg. 8 (2016) S. 311 - 325
    Online Volltext: dx.doi.org/
  • Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Gulbins, Erich; Edwards, Michael J
    Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 4, S. 1262 - 1270
    Online Volltext: dx.doi.org/ (Open Access)
  • Tavakoli Tabazavareh, Shaghayegh; Seitz, Aaron P.; Jernigan, Peter L.; Sehl, Carolin; Keitsch, Simone; Lang, Stephan; Kahl, Barbara C.; Edwards, Michael John Richard; Grassmé, Heike; Gulbins, Erich; Becker-Flegler, Katrin
    Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis
    In: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 6, S. 2094 - 2102
    Online Volltext: dx.doi.org/ (Open Access)
  • Adams, Constantin; Icheva, Vanya; Deppisch, Caroline; Lauer, Josefine; Herrmann, Gloria; Graepler-Mainka, Ute; Heyder, Susanne; Gulbins, Erich; Riethmueller, Joachim
    Long-Term Pulmonal Therapy of Cystic Fibrosis-Patients with Amitriptyline
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 2, S. 565 - 572
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoehn, Richard; Monse, Marlene; Pohl, Ella; Wranik, Sina; Wilker, Barbara; Keitsch, Simone; Soddemann, Matthias; Kornhuber, Johannes; Kohnen, Marcus; Edwards, Michael J; Grassmé, Heike; Gulbins, Erich
    Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System
    In: Neurosignals Jg. 24 (2016) Nr. 1, S. 48 - 58
    Online Volltext: dx.doi.org/ (Open Access)
  • Leanza, Luigi; Managò, Antonella; Zoratti, Mario; Gulbins, Erich; Szabo, Ildiko
    Pharmacological targeting of ion channels for cancer therapy : In vivo evidences
    In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Jg. 1863 (2016) Nr. 6 B, S. 1385 - 1397
    Online Volltext: dx.doi.org/ (Open Access)
  • Makdessi, Samar Al; Sweidan, Hicham; Schmid, Evi; Weimar, Udo; Gulbins, Erich; Lang, Florian
    Quantitative Determination of Ceramide Molecular Species in Dendritic Cells
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 4, S. 1608 - 1617
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Anne; Grassme, Heike; Hoehn, Richard; Wilker, Barbara; Soddemann, Matthias; Kohnen, Marcus; Edwards, Michael J.; Kornhuber, Johannes; Gulbins, Erich
    Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 2, S. 701 - 801
    Online Volltext: dx.doi.org/ (Open Access)
  • Zoicas, Iulia; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes
    Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory
    In: PLoS ONE Jg. 11 (2016) Nr. 9, S. e0162498
    Online Volltext: dx.doi.org/ (Open Access)
  • Carpinteiro, Alexander; Beckmann, Nadine; Seitz, Aaron; Hessler, Gabriele; Wilker, Barbara; Soddemann, Matthias; Helfrich, Iris; Edelmann, Bärbel; Gulbins, Erich; Becker, Katrin Anne
    Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis
    In: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 1, S. 1 - 14
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Anne; Grassmé, Heike; Hoehn, Richard; Kohnen, Marcus; Edwards, Michael J; Kornhuber, Johannes; Gulbins, Erich
    Role of Janus-Kinases in Major Depressive Disorder
    In: Neurosignals Jg. 24 (2016) Nr. 1, S. 71 - 80
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Erich; Walter, Silke; Becker-Flegler, Katrin; Halmer, Ramona; Liu, Yang; Reichel, Martin; Edwards, Michael J; Müller, Christian P; Fassbender, Klaus; Kornhuber, Johannes
    A central role for the acid sphingomyelinase/ceramide system in neurogenesis and major depression
    In: Journal of Neurochemistry Jg. 134 (2015) Nr. 2, S. 183 - 192
    Online Volltext: dx.doi.org/
  • Peng, Huiming; Li, Cao; Kadow, Stephanie; Henry, Brian D.; Steinmann, Jörg; Becker, Katrin Anne; Riehle, Andrea; Beckmann, Natalie; Wilker, Barbara; Li, Pin-Lan; Pritts, Timothy; Edwards, Michael J.; Zhang, Yang; Gulbins, Erich; Grassmé, Heike
    Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis
    In: Journal of Molecular Medicine Jg. 93 (2015) Nr. 6, S. 675 - 689
    Online Volltext: dx.doi.org/ (Open Access)
  • Reichel, Martin; Hönig, Stefanie; Liebisch, Gerhard; Lüth, Anja; Kleuser, Burkhard; Gulbins, Erich; Schmitz, Gerd; Kornhuber, Johannes
    Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients
    In: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Jg. 1851 (2015) Nr. 11, S. 1501 - 1510
    Online Volltext: dx.doi.org/
  • Müller, Christian P.; Reichel, Martin; Mühle, Christiane; Rhein, Cosima; Gulbins, Erich; Kornhuber, Johannes
    Brain membrane lipids in major depression and anxiety disorders
    In: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Jg. 1851 (2015) Nr. 8, S. 1052 - 1065
    Online Volltext: dx.doi.org/ (Open Access)
  • Seitz, Aaron P.; Gulbins, Erich; Pewzner-Jung, Yael; Edwards, Michael J.; Grassme, Heike
    Ceramide and sphingosine in pulmonary infections
    In: Biological Chemistry Jg. 396 (2015) Nr. 6-7, S. 611 - 620
    Online Volltext: dx.doi.org/
  • Lang, Elisabeth; Bissinger, Rosi; Gulbins, Erich; Lang, Florian
    Ceramide in the regulation of eryptosis, the suicidal erythrocyte death
    In: Apoptosis Jg. 2 (2015) Nr. 5, S. 758 - 767
    Online Volltext: dx.doi.org/
  • Lang, Elisabeth; Gatidis, Sergios; Freise, Noemi F; Bock, Hans; Kubitz, Ralf; Lauermann, Christian; Orth, Hans Martin; Klindt, Caroline; Schuier, Maximilian; Keitel, Verena; Reich, Maria; Liu, Guilai; Schmidt, Sebastian; Xu, Haifeng C; Qadri, Syed M; Herebian, Diran; Pandyra, Aleksandra A; Mayatepek, Ertan; Gulbins, Erich; Lang, Florian; Häussinger, Dieter; Lang, Karl S.; Föller, Michael; Lang, Philipp A
    Conjugated Bilirubin Triggers Anemia by Inducing Erythrocyte Death
    In: Hepatology Jg. 61 (2015) Nr. 1, S. 275 - 284
    Online Volltext: dx.doi.org/ (Open Access)
  • Lee, Hyunmi; Rotolo, Jimmy A; Mesicek, Judith; Penate-Medina, Tuula; Rimner, Andreas; Liao, Wen-Chieh; Yin, Xianglei; Ragupathi, Govind; Ehleiter, Desiree; Gulbins, Erich; Zhai, Dayong; Reed, John C; Haimovitz-Friedman, Adriana; Fuks, Zvi; Kolesnick, Richard
    Correction : Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation
    In: PLoS ONE Jg. 10 (2015) Nr. 12, S. e0146210
    Online Volltext: dx.doi.org/ (Open Access)
  • Managò, A.; Leanza, L.; Carraretto, L.; Sassi, N.; Grancara, S.; Quintana-Cabrera, R.; Trimarco, V.; Toninello, A.; Scorrano, L.; Trentin, L.; Semenzato, G.; Gulbins, Erich; Zoratti, M.; Szabò, I.
    Early effects of the antineoplastic agent salinomycin on mitochondrial function
    In: Cell Death and Disease Jg. 6 (2015) Nr. 10, e1930
    Online Volltext: dx.doi.org/ (Open Access)
  • Chen, Yang; Li, Xiang; Boini, Krishna M.; Pitzer, Ashley L.; Gulbins, Erich; Zhang, Yang; Li, Pin-Lan
    Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis
    In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Jg. 1853 (2015) Nr. 2, S. 396 - 408
    Online Volltext: dx.doi.org/ (Open Access)
  • Henry, Brian D; Babiychuk, Eduard B; Draeger, Annette; Kadioglu, Aras; Gulbins, Erich; Scherag, Andre; Wolfmeier, Heidi; Luginbühl, Miriam; Japtok, Lukasz; Kleuser, Burkhard; Steinmann, Jörg; Mühlemann, Kathrin; Edwards, Michael J; Ziobro, Regan; Bricio-Moreno, Laura; Gore, Suzanna; Becker-Flegler, Katrin; Neill, Daniel R
    Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice
    In: Nature Biotechnology Jg. 33 (2015) Nr. 1, S. 81 - 88
    Online Volltext: dx.doi.org/
  • Gulbins, Erich
    Highlight : molecular medicine of sphingolipids
    In: Biological Chemistry Jg. 396 (2015) Nr. 6-7, S. 569 - 571
    Online Volltext: dx.doi.org/
  • Schumacher, Fabian; Chakraborty, Sudipta; Kleuser, Burkhard; Gulbins, Erich; Schwerdtle, Tanja; Aschner, Michael; Bornhorst, Julia
    Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans
    In: Talanta: The International Journal of Pure and Applied Analytical Chemistry Jg. 144 (2015) S. 71 - 79
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Grassmé, Heike; Jernigan, Peter L; Hoehn, Richard S; Wilker, Barbara; Soddemann, Matthias; Edwards, Michael J; Müller, Christian P; Kornhuber, Johannes; Gulbins, Erich
    Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression
    In: Neurosignals Jg. 23 (2015) Nr. 1, S. 84 - 92
    Online Volltext: dx.doi.org/ (Open Access)
  • Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher M.; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B
    Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice
    In: Hepatology Research Jg. 45 (2015) Nr. 3, S. 305 - 314
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Hilker, Rolf; Munder, Antje; Klockgether, Jens; Losada, Patricia M.oran; Chouvarine, Philippe; Cramer, Nina; Davenport, Colin F.; Dethlefsen, Sarah; Fischer, Sebastian; Peng, Huiming; Schönfelder, Torben; Türk, Oliver; Wiehlmann, Lutz; Wölbeling, Florian; Gulbins, Erich; Goesmann, Alexander; Tümmler, Burkhard
    Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment
    In: Environmental Microbiology Jg. 17 (2015) Nr. 1, S. 29 - 46
    Online Volltext: dx.doi.org/ (Open Access)
  • Managò, Antonella; Becker-Flegler, Katrin; Carpinteiro, Alexander; Wilker, Barbara; Soddemann, Matthias; Seitz, Aaron P.; Edwards, Michael John Richard; Grassmé, Heike; Szabò, Ildikò M.; Gulbins, Erich
    Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase
    In: Antioxidants and Redox Signaling Jg. 22 (2015) Nr. 13, S. 1097 - 1110
    Online Volltext: dx.doi.org/ (Open Access)
  • Carpinteiro, Alexander; Becker-Flegler, Katrin; Japtok, Lukasz; Hessler, Gabriele; Keitsch, Simone; Požgajovà, Miroslava; Schmid, Kurt Werner; Adams, Constantin; Müller, Stefan; Kleuser, Burkhard; Edwards, Michael J.; Grassmé, Heike; Helfrich, Iris; Gulbins, Erich
    Regulation of hematogenous tumor metastasis by acid sphingomyelinase
    In: EMBO Molecular Medicine Jg. 7 (2015) Nr. 6, S. 714 - 734
    Online Volltext: dx.doi.org/ (Open Access)
  • Nojima, Hiroyuki; Freeman, Christopher M; Gulbins, Erich; Lentsch, Alex B
    Sphingolipids in liver injury, repair and regeneration
    In: Biological Chemistry Jg. 396 (2015) Nr. 6-7, S. 633 - 643
    Online Volltext: dx.doi.org/
  • Jernigan, Peter L.; Hoehn, Richard S.; Grassmé, Heike; Edwards, Michael J.; Müller, Christian P.; Kornhuber, Johannes; Gulbins, Erich
    Sphingolipids in major depression
    In: Neurosignals Jg. 23 (2015) S. 49 - 58
    Online Volltext: dx.doi.org/ (Open Access)
  • Seitz, Aaron; Gulbins, Erich; Edwards, Michael J.; Freeman, Christopher M.; Lentsch, Alex B.
    Sphingosine Prevents Adherence of Pseudomonas Aeruginosa to Endotracheal Tubes : A Novel Strategy to Prevent Ventilator-Associated Pneumonia
    In: Journal of the American College of Surgeons Jg. 221 (2015) Nr. 4 Suppl., S. S44
    Online Volltext: dx.doi.org/
  • Leanza, Luigi; Venturini, Elisa; Kadow, Stephanie; Carpinteiro, Alexander; Gulbins, Erich; Becker, Katrin Anne
    Targeting a mitochondrial potassium channel to fight cancer
    In: Cell Calcium Jg. 58 (2015) Nr. 1, S. 131 - 138
    Online Volltext: dx.doi.org/
  • Merches, Katja; Khairnar, Vishal; Knuschke, Torben; Shaabani, Namir; Honke, Nadine; Duhan, Vikas; Recher, Mike; Navarini, Alexander A.; Hardt, Cornelia; Häussinger, Dieter; Tümmler, Burkhard; Gulbins, Erich; Futerman, Anthony H.; Hoffmann, Daniel; Lang, Florian; Lang, Philipp A.; Westendorf, Astrid; Lang, Karl S.
    Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infection
    In: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 6, S. 2379 - 2392
    Online Volltext: dx.doi.org/ (Open Access)
  • Münzer, Patrick; Borst, Oliver; Walker, Britta; Schmid, Evi; Feijge, Marion A. H.; Cosemans, Judith M. E. M.; Chatterjee, Madhumita; Schmidt, Eva-Maria; Schmidt, Sebastian; Towhid, Syeda T.; Leibrock, Christina; Elvers, Margitta; Schaller, Martin; Seizer, Peter; Ferlinz, Klaus; May, Andreas E.; Gulbins, Erich; Heemskerk, Johan W. M.; Gawaz, Meinrad; Lang, Florian
    Acid Sphingomyelinase Regulates Platelet Cell Membrane Scrambling, Secretion, and Thrombus Formation
    In: Arteriosclerosis, Thrombosis, and Vascular Biology Jg. 34 (2014) Nr. 1, S. 61 - 71
    Online Volltext: dx.doi.org/
  • Li, Xiang; Zhang, Yang; Xia, Min; Gulbins, Erich; Boini, Krishna M.; Li, Pin-Lan
    Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration : Implication of a novel role of inflammasome in atherogenesis
    In: PLoS ONE Jg. 9 (2014) Nr. 1, S. e87552
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Yang; Xu, Ming; Xia, Min; Li, Xiang; Boini, Krishna M.; Wang, Mi; Gulbins, Erich; Ratz, Paul A.; Li, Pin-Lan
    Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene
    In: Cardiovascular Research Jg. 102 (2014) Nr. 1, S. 68 - 78
    Online Volltext: dx.doi.org/
  • Simonis, Alexander; Hebling, Sabrina; Gulbins, Erich; Schneider-Schaulies, Sibylle; Schubert-Unkmeir, Alexandra
    Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells
    In: PLoS Pathogens Jg. 10 (2014) Nr. 6, S. e1004160
    Online Volltext: dx.doi.org/ (Open Access)
  • Vidigal, Pedrina G.; Müsken, Mathias; Becker, Katrin A.; Häussler, Susanne; Wingender, Jost; Steinmann, Eike; Kehrmann, Jan; Gulbins, Erich; Buer, Jan; Rath, Peter-Michael; Steinmann, Jörg
    Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm
    In: PLoS ONE Jg. 9 (2014) Nr. 4, S. e92876
    Online Volltext: dx.doi.org/ (Open Access)
  • Beckmann, N.; Sharma, D.; Gulbins, Erich; Becker-Flegler, Katrin; Edelmann, Bärbel
    Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons
    In: Frontiers in Physiology (2014) Nr. 5, S. 331
    Online Volltext: dx.doi.org/ (Open Access)
  • Siegmann, Nanna; Worbs, David; Effinger, Frauke; Bormann, Tobias; Gebhardt, Madlen; Ulrich, Martina; Wermeling, Fredrik; Müller-Hermelink, Eva; Biedermann, Tilo; Tighe, Mike; Edwards, Michael J; Caldwell, Charles; Leadbetter, Elizabeth; Karlsson, Mikael C I; Becker-Flegler, Katrin; Gulbins, Erich; Döring, Gerd
    Invariant natural killer T (iNKT) cells prevent autoimmunity, but induce pulmonary inflammation in cystic fibrosis
    In: Cellular Physiology and Biochemistry Jg. 34 (2014) Nr. 1, S. 56 - 70
    Online Volltext: dx.doi.org/ (Open Access)
  • Brown, Mary Beth; Hunt, William R; Noe, Julie E; Rush, Natalia I; Schweitzer, Kelly S; Leece, Thomas C; Moldobaeva, Aigul; Wagner, Elizabeth M; Dudek, Steven M; Poirier, Christophe; Presson, Robert G; Gulbins, Erich; Petrache, Irina
    Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke
    In: Pulmonary Circulation Jg. 4 (2014) Nr. 2, S. 260 - 268
    Online Volltext: dx.doi.org/ (Open Access)
  • Neuber, Corinna; Schumacher, Fabian; Gulbins, Erich; Kleuser, Burkhard P.
    Method to Simultaneously Determine the Sphingosine 1-Phosphate Breakdown Product (2E)-Hexadecenal and Its Fatty Acid Derivatives Using Isotope-Dilution HPLC–Electrospray Ionization–Quadrupole/Time-of-Flight Mass Spectrometry
    In: Analytical Chemistry Jg. 86 (2014) Nr. 18, S. 9065 - 9073
    Online Volltext: dx.doi.org/
  • Leanza, L; Zoratti, M; Gulbins, Erich; Szabo, I
    Mitochondrial ion channels as oncological targets
    In: Oncogene Jg. 33 (2014) Nr. 49, S. 5569 - 5581
    Online Volltext: dx.doi.org/
  • Grassmé, Heike; Carpinteiro, Alexander; Edwards, Michael J; Gulbins, Erich; Becker-Flegler, Katrin
    Regulation of the inflammasome by ceramide in cystic fibrosis lungs
    In: Cellular Physiology and Biochemistry Jg. 34 (2014) Nr. 1, S. 45 - 55
    Online Volltext: dx.doi.org/ (Open Access)
  • Yang, Wenting; Schmid, Evi; Nurbaeva, Meerim K.; Szteyn, Kalina; Leibrock, Christina B.; Yan, Jing; Schaller, Martin; Gulbins, Erich; Shumilina, Ekatarina V.; Lang, Florian
    Role of acid sphingomyelinase in the regulation of mast cell function
    In: Clinical & Experimental Allergy Jg. 44 (2014) Nr. 1, S. 79 - 90
    Online Volltext: dx.doi.org/
  • Mühle, Christiane; Amova, V.; Biermann, T.; Bayerlein, K.; Richter-Schmidinger, T.; Kraus, T.; Reichel, M.; Gulbins, Erich; Kornhuber, J.
    Sex-dependent decrease of sphingomyelinase activity during alcohol withdrawal treatment
    In: Cellular Physiology and Biochemistry Jg. 34 (2014) S. 71 - 81
    Online Volltext: dx.doi.org/ (Open Access)
  • Pewzner-Jung, Yael; Tavakoli Tabazavareh, Shaghayegh; Grassmé, Heike; Becker, Katrin A.; Japtok, Lukasz; Steinmann, Jörg; Joseph, Tammar; Lang, Stephan; Tuemmler, Burkhard; Schuchman, Edward H.; Lentsch, Alex B.; Kleuser, Burkhard P.; Edwards, Michael J. R.; Futerman, Anthony H.; Gulbins, Erich
    Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa
    In: EMBO Molecular Medicine Jg. 6 (2014) Nr. 9, S. 1205 - 1214
    Online Volltext: dx.doi.org/ (Open Access)
  • Kornhuber, Johannes; Müller, Christian P.; Becker, Katrin Anne; Reichel, Martin; Gulbins, Erich
    The ceramide system as a novel antidepressant target
    In: Trends in Pharmacological Sciences Jg. 35 (2014) Nr. 6, S. 293 - 304
    Online Volltext: dx.doi.org/
  • Reichel, M.; Richter-Schmidinger, T.; Mühle, C.; Rhein, C.; Alexopoulos, P.; Schwab, S. G.; Gulbins, Erich; Kornhuber, J.
    The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy
    In: Cellular Physiology and Biochemistry Jg. 34 (2014) Nr. 1, S. 82 - 91
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Erich; Palmada, Monica; Reichel, Martin; Lüth, Anja; Böhmer, Christoph; Amato, Davide; Müller, Christian P.; Tischbirek, Carsten H.; Groemer, Teja W.; Tabatabai, Ghazaleh; Becker-Flegler, Katrin; Tripal, Philipp; Staedtler, Sven; Ackermann, Teresa F.; Van Brederode, Johannes; Alzheimer, Christian; Weller, Michael; Lang, Undine E.; Kleuser, Burkhard; Grassmé, Heike; Kornhuber, Johannes
    Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs
    In: Nature Medicine Jg. 19 (2013) Nr. 7, S. 934 - 938
    Online Volltext: dx.doi.org/
  • Ziobro, Regan M.; Henry, Brian D.; Lentsch, Alex B.; Edwards, Michael J.; Riethmüller, Joachim; Gulbins, Erich
    Ceramide in cystic fibrosis
    In: Clinical Lipidology Jg. 8 (2013) Nr. 6, S. 681 - 691
    Online Volltext: dx.doi.org/
  • Ziobro, Regan; Henry, Brian; Edwards, Michael J.; Lentsch, Alex B.; Gulbins, Erich
    Ceramide mediates lung fibrosis in cystic fibrosis
    In: Biochemical and Biophysical Research Communications (BBRC) Jg. 434 (2013) Nr. 4, S. 705 - 709
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mühle, Christiane; Huttner, Hagen B.; Walter, Silke; Reichel, Martin; Canneva, Fabio; Lewczuk, Piotr; Gulbins, Erich; Kornhuber, Johannes
    Characterization of Acid Sphingomyelinase Activity in Human Cerebrospinal Fluid
    In: PLoS ONE Jg. 8 (2013) Nr. 5, S. e62912
    Online Volltext: dx.doi.org/ (Open Access)
  • Leanza, L; Trentin, L; Becker-Flegler, Katrin; Frezzato, F; Zoratti, M; Semenzato, G; Gulbins, Erich; Szabo, I
    Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia
    In: Leukemia Jg. 27 (2013) Nr. 8, S. 1782 - 1785
    Online Volltext: dx.doi.org/
  • Abed, Majed; Towhid, Syeda T.; Pakladok, Tatsiana; Alesutan, Ioana; Götz, Friedrich; Gulbins, Erich; Lang, Florian
    Effect of bacterial peptidoglycan on erythrocyte death and adhesion to endothelial cells
    In: International Journal of Medical Microbiology (IJMM) Jg. 303 (2013) Nr. 4, S. 182 - 189
    Online Volltext: dx.doi.org/
  • Johnson, Kristian T.M.; Wiesweg, B.; Schott, Matthias; Ehlers, Margret; Müller, Martin R.; Minich, Waldemar B.; Nagayama, Yuji; Gulbins, Erich; Eckstein, Anja; Berchner-Pfannschmidt, Utta
    Examination of orbital tissues in murine models of graves' disease reveals expression of UCP-1 and the TSHR in retrobulbar adipose tissues
    In: Hormone and Metabolic Research Jg. 45 (2013) Nr. 6, S. 401 - 407
    Online Volltext: dx.doi.org/
  • Gramatzki, Dorothee; Herrmann, Caroline; Happold, Caroline; Becker, Katrin Anne; Gulbins, Erich; Weller, Michael; Tabatabai, Ghazaleh
    Glioma Cell Death Induced by Irradiation or Alkylating Agent Chemotherapy Is Independent of the Intrinsic Ceramide Pathway
    In: PLoS ONE Jg. 8 (2013) Nr. 5, S. e63527
    Online Volltext: dx.doi.org/ (Open Access)
  • Leanza, Luigi; Biasutto, Lucia; Managò, Antonella; Gulbins, Erich; Zoratti, Mario; Szabò, Ildikò
    Intracellular ion channels and cancer
    In: Frontiers in Physiology Jg. 4 (2013) S. 227
    Online Volltext: dx.doi.org/
  • Gulbins, Erich; Kolesnick, Richard N
    It takes a CAD to kill a tumor cell with a LMP
    In: Cancer Cell Jg. 24 (2013) Nr. 3, S. 279 - 281
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Ming; Li, Xiao-xue; Xiong, Jing; Xia, Min; Gulbins, Erich; Zhang, Yang; Li, Pin-Lan
    Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes
    In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Jg. 1833 (2013) Nr. 12, S. 3288 - 3236
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Henry, Brian; Möller, Christina; Dimanche-Boitrel, Marie-Therese; Gulbins, Erich; Becker, Katrin Anne
    Targeting the ceramide system in cancer
    In: Cancer Letters Jg. 332 (2013) Nr. 2, S. 286 - 294
    Online Volltext: dx.doi.org/
  • Nährlich, Lutz; Mainz, Jochen G.; Adams, Constantin; Engel, Corinna; Herrmann, Gloria; Icheva, Vanya; Lauer, Josefine; Deppisch, Caroline; Wirth, Andreas; Unger, Katy; Graepler-Mainka, Ute; Hector, Andreas; Heyder, Susanne; Stern, Martin; Döring, Gerd; Gulbins, Erich; Riethmüller, Joachim
    Therapy of CF-patients with amitriptyline and placebo-a randomised, double-blind, placebo-controlled phase IIb multicenter, cohort-study
    In: Cellular Physiology and Biochemistry Jg. 31 (2013) Nr. 4-5, S. 505 - 512
    Online Volltext: dx.doi.org/ (Open Access)
  • Grassmé, Heike; Becker, Katrin; Gulbins, Erich
    Wirkungsvolle Lipide : Sphingolipide, bakterielle Infektionen und zystische Fibrose
    In: Unikate: Berichte aus Forschung und Lehre (2013) Nr. 44: Medizin: 50 Jahre Universitätsklinikum Essen, S. 22 - 31
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rhein, Cosima; Tripal, Philipp; Seebahn, Angela; Konrad, Alice; Kramer, Marcel; Nagel, Christine; Kemper, Jonas; Bode, Jens; Mühle, Christiane; Gulbins, Erich; Reichel, Martin; Becker, Cord-Michael; Kornhuber, Johannes
    Functional implications of novel human acid sphingomyelinase splice variants
    In: PLoS ONE Jg. 7 (2012) Nr. 4, S. e35467
    Online Volltext: dx.doi.org/ (Open Access)
  • Leanza, L.; Zoratti, M.; Gulbins, Erich; Szabò, I.
    Induction of Apoptosis in Macrophages via Kv1.3 and Kv1.5 Potassium Channels
    In: Current Medicinal Chemistry Jg. 19 (2012) Nr. 31, S. 5394 - 5404
    Online Volltext: dx.doi.org/
  • Leanza, Luigi; Henry, Brian; Sassi, Nicola; Zoratti, Mario; Chandy, K. George; Gulbins, Erich; Szabò, Ildikò
    Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells
    In: EMBO Molecular Medicine Jg. 4 (2012) Nr. 7, S. 577 - 593
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Xiang; Gulbins, Erich; Zhang, Yang
    Oxidative stress triggers Ca²⁺-dependent lysosome trafficking and activation of acid sphingomyelinase
    In: Cellular Physiology and Biochemistry Jg. 30 (2012) Nr. 4, S. 815 - 826
    Online Volltext: dx.doi.org/ (Open Access)
  • Szabò, Ildikò; Leanza, Luigi; Gulbins, Erich; Zoratti, Mario
    Physiology of potassium channels in the inner membrane of mitochondria
    In: Pflügers Archiv: European Journal of Physiology Jg. 463 (2012) Nr. 2, S. 231 - 246
    Online Volltext: dx.doi.org/
  • Becker-Flegler, Katrin; Henry, Brian; Ziobro, Regan; Tümmler, Burkhard; Gulbins, Erich; Grassmé, Heike
    Role of CD95 in pulmonary inflammation and infection in cystic fibrosis
    In: Journal of Molecular Medicine Jg. 90 (2012) Nr. 9, S. 1011 - 1023
    Online Volltext: dx.doi.org/
  • Li, Xiang; Gulbins, Erich; Zhang, Yang
    Role of kinase suppressor of ras-1 in lipopolysaccharide-induced acute lung injury
    In: Cellular Physiology and Biochemistry Jg. 30 (2012) Nr. 4, S. 905 - 914
    Online Volltext: dx.doi.org/
  • Abed, Majed; Towhid, Syeda T.; Mia, Sobuj; Pakladok, Tatsiana; Alesutan, Ioana; Borst, Oliver; Gawaz, Meinrad; Gulbins, Erich; Lang, Florian
    Sphingomyelinase-induced adhesion of eryptotic erythrocytes to endothelial cells
    In: American Journal of Physiology: Cell Physiology Jg. 303 (2012) Nr. 9, S. C991 - C999
    Online Volltext: dx.doi.org/
  • Meyer zu Hörste, Melissa; Eckstein, Anja; Gulbins, Erich; Fischer, Jens W.; Göthert, Joachim Rudolf; Pink, Mario; Ströher, Elena; Berchner-Pfannschmidt, Utta; Schmitz-Spanke, Simone
    A Novel Mechanism Involved in the Pathogenesis of Graves Ophthalmopathy (GO) : Clathrin Is a Possible Targeting Molecule for Inhibiting Local Immune Response in the Orbit
    In: The Journal of Clinical Endocrinology & Metabolism (JCEM) Jg. 96 (2011) Nr. 11, S. E1727 - 1736
    Online Volltext: dx.doi.org/
  • Cheng, Yu; Gulbins, Erich; Siemen, Detlef
    Activation of the Permeability Transition Pore by Bax via Inhibition of the Mitochondrial BK Channel
    In: Cellular Physiology and Biochemistry Jg. 27 (2011) Nr. 3-4, S. 191 - 200
    Online Volltext: dx.doi.org/
  • Reichel, Martin; Beck, Johannes; Mühle, Christiane; Rotter, Andrea; Bleich, Stefan; Gulbins, Erich; Kornhuber, Johannes
    Activity of Secretory Sphingomyelinase Is Increased in Plasma of Alcohol‐Dependent Patients
    In: Alcoholism: Clinical and Experimental Research Jg. 35 (2011) Nr. 10, S. 1852 - 1859
    Online Volltext: dx.doi.org/
  • Munder, Antje; Wölbeling, Florian; Kerber-Momot, Tanja; Wedekind, Dirk; Baumann, Ulrich; Gulbins, Erich; Tümmler, Burkhard
    Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent
    In: Respiratory Research Jg. 12 (2011)
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lang, Florian; Ullrich, Susanne; Gulbins, Erich
    Ceramide formation as a target in beta-cell survival and function
    In: Expert Opinion on Therapeutic Targets Jg. 15 (2011) Nr. 9, S. 1061 - 1071
    Online Volltext: dx.doi.org/
  • Dimanche-Boitrel, Marie-Thérèse; Rebillard, Amélie; Gulbins, Erich
    Ceramide in Chemotherapy of Tumors
    In: Recent Patents on Anti-Cancer Drug Discovery Jg. 6 (2011) Nr. 3, S. 284 - 293
    Online Volltext: dx.doi.org/
  • Avota, Elita; Gulbins, Erich; Schneider-Schaulies, Sibylle
    DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells
    In: PLoS Pathogens Jg. 7 (2011) Nr. 2, S. e1001290
    Online Volltext: dx.doi.org/ (Open Access)
  • Kornhuber, Johannes; Muehlbacher, Markus; Trapp, Stefan; Pechmann, Stefanie; Friedl, Astrid; Reichel, Martin; Mühle, Christiane; Terfloth, Lothar; Groemer, Teja W.; Spitzer, Gudrun M.; Liedl, Klaus R.; Gulbins, Erich; Tripal, Philipp
    Identification of novel functional inhibitors of acid sphingomyelinase
    In: PLoS ONE Jg. 6 (2011) Nr. 8,
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Yang; Li, Xiang; Carpinteiro, Alexander; Goettel, Jeremy A.; Soddemann, Matthias; Gulbins, Erich
    Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections
    In: Nature Medicine Jg. 17 (2011) Nr. 3, S. 341 - 346
    Online Volltext: dx.doi.org/
  • Becker-Flegler, Katrin; Henry, Brian; Ziobro, Regan; Riethmüller, Joachim; Gulbins, Erich
    Lipids in cystic fibrosis
    In: Expert Review of Respiratory Medicine Jg. 5 (2011) Nr. 4, S. 527 - 535
    Online Volltext: dx.doi.org/
  • Lee, Hyunmi; Rotolo, Jimmy A.; Mesicek, Judith; Penate-Medina, Tuula; Rimner, Andreas; Liao, Wen-Chieh; Yin, Xianglei; Ragupathi, Govind; Ehleiter, Desiree; Gulbins, Erich; Zhai, Dayong; Reed, John C.; Haimovitz-Friedman, Adriana; Fuks, Zvi; Kolesnick, Richard
    Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation
    In: PLoS ONE Jg. 6 (2011) Nr. 6, S. 0019783
    Online Volltext: dx.doi.org/ (Open Access)
  • Szabò, I.; Soddemann, M.; Leanza, L.; Zoratti, M.; Gulbins, Erich
    Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts : Novel insights into the molecular mechanisms of Bax-induced apoptosis
    In: Cell Death and Differentiation Jg. 18 (2011) Nr. 3, S. 427 - 438
    Online Volltext: dx.doi.org/
  • Becker, Katrin Anne; Tümmler, Burkhard; Gulbins, Erich; Grassmé, Heike
    Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death
    In: Biochemical and Biophysical Research Communications (BBRC) Jg. 403 (2010) Nr. 3-4, S. 368 - 374
    Online Volltext: dx.doi.org/
  • Becker-Flegler, Katrin; Riethmüller, Joachim; Lüth, Anja; Döring, Gerd; Kleuser, Burkhard; Gulbins, Erich
    Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis
    In: American Journal of Respiratory Cell and Molecular Biology Jg. 42 (2010) Nr. 6, S. 716 - 724
    Online Volltext: dx.doi.org/
  • Zhang, Yang; Li, Xiang; Grassmé, Heike; Döring, Gerd; Gulbins, Erich
    Alterations in Ceramide Concentration and pH Determine the Release of Reactive Oxygen Species by Cftr-Deficient Macrophages on Infection
    In: The Journal of Immunology (JI) Jg. 184 (2010) Nr. 9, S. 5104 - 5111
    Online Volltext: dx.doi.org/
  • Ulrich, Martina; Worlitzsch, Dieter; Viglio, Simona; Siegmann, Nanna; Iadarola, Paolo; Shute, Janis K.; Geiser, Marianne; Pier, Gerald B.; Friedel, Godehard; Barr, Mark L.; Schuster, Antje; Meyer, Keith C.; Ratjen, Felix; Bjarnsholt, Thomas; Gulbins, Erich; Döring, Gerd
    Alveolar inflammation in cystic fibrosis
    In: Journal of Cystic Fibrosis Jg. 9 (2010) Nr. 3, S. 217 - 227
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Sassi, Nicola; De Marchi, Umberto; Fioretti, Bernard; Biasutto, Lucia; Gulbins, Erich; Franciolini, Fabio; Szabò, Ildikò; Zoratti, Mario
    An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca²⁺-activated K⁺ channel mtKCₐ3.1
    In: Biochimica et Biophysica Acta (BBA) - Bioenergetics Jg. 1797 (2010) Nr. 6-7, S. 1260 - 1267
    Online Volltext: dx.doi.org/ (Open Access)
  • Grassmé, Heike; Becker-Flegler, Katrin; Zhang, Yang; Gulbins, Erich
    CFTR-dependent susceptibility of the cystic fibrosis-host to Pseudomonas aeruginosa
    In: International Journal of Medical Microbiology (IJMM) Jg. 300 (2010) Nr. 8, S. 578 - 583
    Online Volltext: dx.doi.org/
  • Verdurmen, Wouter P.R.; Thanos, Melissa; Ruttekolk, Ivo R.; Gulbins, Erich; Brock, Roland
    Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase : implications for uptake
    In: Journal of Controlled Release Jg. 147 (2010) Nr. 2, S. 171 - 179
    Online Volltext: dx.doi.org/
  • Becker, Katrin Anne; Grassmé, Heike; Zhang, Yang; Gulbins, Erich
    Ceramide in pseudomonas aeruginosa infections and cystic fibrosis
    In: Cellular Physiology and Biochemistry Jg. 26 (2010) Nr. 1, S. 57 - 66
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Florian; Gulbins, Erich; Lang, Philipp A.; Zappulla, Donatella; Föller, Michael
    Ceramide in suicidal death of erythrocytes
    In: Cellular Physiology and Biochemistry Jg. 26 (2010) Nr. 1, S. 21 - 28
    Online Volltext: dx.doi.org/ (Open Access)
  • Gulbins, Erich; Sassi, Nicola; Grassmè, Heike; Leanza, Luigi; Zoratti, Mario; Szabò, Ildikò
    Contribution of the mitochondrial potassium channel Kv1.3 to the regulation of programmed cell death
    In: Biochimica et Biophysica Acta (BBA) - Bioenergetics Jg. 1797 (2010) Nr. Supplement, S. 132 - 133
    Online Volltext: dx.doi.org/ (Open Access)
  • Szabò, Ildikò; Zoratti, Mario; Gulbins, Erich
    Contribution of voltage-gated potassium channels to the regulation of apoptosis
    In: FEBS Letters Jg. 584 (2010) Nr. 10, S. 2049 - 2056
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Elisabeth; Lang, Philipp A.; Shumilina, Ekaterina; Qadri, Syed M.; Kucherenko, Yuliya; Kempe, Daniela S.; Föller, Michael; Capasso, Anna; Wieder, Thomas; Gulbins, Erich; Clemen, Christoph S.; Herr, Claudia; Noegel, Angelika A.; Huber, Stephan M.; Lang, Florian
    Enhanced eryptosis of erythrocytes from gene-targeted mice lacking annexin A7
    In: Pflügers Archiv: European Journal of Physiology Jg. 460 (2010) Nr. 3, S. 667 - 676
    Online Volltext: dx.doi.org/
  • Kornhuber, Johannes; Tripal, Philipp; Reichel, Martin; Mühle, Christiane; Rhein, Cosima; Muehlbacher, Markus; Groemer, Teja W.; Gulbins, Erich
    Functional inhibitors of acid sphingomyelinase (FIASMAS) : A novel pharmacological group of drugs with broad clinical applications
    In: Cellular Physiology and Biochemistry Jg. 26 (2010) Nr. 1, S. 9 - 20
    Online Volltext: dx.doi.org/ (Open Access)
  • Reichel, Martin; Greiner, Elisabeth; Richter-Schmidinger, Tanja; Yedibela, Özlem; Tripal, Philipp; Jacobi, Andrea; Bleich, Stefan; Gulbins, Erich; Kornhuber, Johannes; Yedibela, Özlem
    Increased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence
    In: Alcoholism: Clinical and Experimental Research Jg. 34 (2010) Nr. 1, S. 46 - 50
    Online Volltext: dx.doi.org/
  • Gulbins, Erich
    Lipids control mucus production in cystic fibrosis
    In: Nature Medicine Jg. 16 (2010) Nr. 3, S. 267 - 268
    Online Volltext: dx.doi.org/
  • Gulbins, Erich; Sassi, Nicola; Grassmè, Heike; Zoratti, Mario; Szabò, Ildikò
    Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes
    In: Biochimica et Biophysica Acta (BBA) - Bioenergetics Jg. 1797 (2010) Nr. 6-7, S. 1251 - 1259
    Online Volltext: dx.doi.org/ (Open Access)
  • Xuan, Nguyen Thi; Shumilina, Ekaterina; Schmid, Evi; Bhavsar, Shefalee K.; Rexhepaj, Rexhep; Götz, Friedrich; Gulbins, Erich; Lang, Florian
    Role of acidic sphingomyelinase in thymol-mediated dendritic cell death
    In: Molecular Nutrition and Food Research Jg. 54 (2010) Nr. 12, S. 1833 - 1841
    Online Volltext: dx.doi.org/
  • Xuan, Nguyen Thi; Shumilina, Ekaterina; Kempe, Daniela S.; Gulbins, Erich; Lang, Florian
    Sphingomyelinase dependent apoptosis of dendritic cells following treatment with amyloid peptides
    In: Journal of Neuroimmunology Jg. 219 (2010) Nr. 1-2, S. 81 - 89
    Online Volltext: dx.doi.org/
  • Perrotta, Cristiana; Bizzozero, Laura; Cazzato, Denise; Morlacchi, Sara; Assi, Emma; Simbari, Fabio; Zhang, Yang; Gulbins, Erich; Bassi, Maria Teresa; Rosa, Patrizia; Clementi, Emilio
    Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function
    In: The Journal of Biological Chemistry (JBC) Jg. 285 (2010) Nr. 51, S. 40240 - 40251
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Becker, Katrin Anne; Riethmüller, Joachim; Zhang, Yang; Gulbins, Erich
    The Role of Sphingolipids and Ceramide in Pulmonary Inflammation in Cystic Fibrosis
    In: Open Respiratory Medicine Journal Jg. 4 (2010) S. 39 - 47
    Online Volltext: dx.doi.org/
  • Xuan, Nguyen Thi; Shumilina, Ekaterina; Gulbins, Erich; Gu, Shuchen; Götz, Friedrich; Lang, Florian
    Triggering of dendritic cell apoptosis by xanthohumol
    In: Molecular Nutrition and Food Research Jg. 54 (2010) Nr. Suppl. 2, S. 214 - S224
    Online Volltext: dx.doi.org/
  • Teichgräber, Volker; Ulrich, Martina; Endlich, Nicole; Riethmüller, Joachim; Wilker, Barbara; De Oliveira-Munding, Cheyla Conceição; Van Heeckeren, Anna M.; Barr, Mark L.; Von Kürthy, Gabriele; Schmid, Kurt Werner; Weller, Michael; Tümmler, Burkhard; Lang, Florian; Grassme, Heike; Döring, Gerd; Gulbins, Erich
    Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
    In: Nature Medicine Jg. 14 (2008) Nr. 4, S. 382 - 391
    Online Volltext: dx.doi.org/ (Open Access)
  • Kornhuber, Johannes; Tripal, Philipp; Reichel, Martin; Terfloth, Lothar; Bleich, Stefan; Wiltfang, Jens; Gulbins, Erich
    Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model
    In: Journal of Medicinal Chemistry Jg. 51 (2008) Nr. 2, S. 219 - 237
    Online Volltext: dx.doi.org/
  • Möröy, Tarik; Zeng, Hui; Jin, Jianmin; Schmid, Kurt Werner; Carpinteiro, Alexander; Gulbins, Erich
    The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response
    In: Immunobiology Jg. 213 (2008) Nr. 3-4, S. 341 - 352
    Online Volltext: dx.doi.org/
  • Schenck, Marcus; Carpinteiro, Alexander; Grassme, Heike; Lang, Florian; Gulbins, Erich
    Ceramide : physiological and pathophysiological aspects
    In: Archives of Biochemistry and Biophysics (ABB) Jg. 462 (2007) Nr. 2, S. 171 - 175
    Online Volltext: dx.doi.org/
  • Schenck, Marcus; vom Dorp, Frank; Börgermann, Christof; Busch, Y.; Carpinteiro, Alexander; Wilker, B.; Keitsch, S.; Schmid, Kurt Werner; Groneberg, M.; Stuschke, Martin; Rübben, Herbert; Gulbins, Erich
    Gründung einer Arbeitsgruppe „Lymphknotenmetastasierung“ am Westdeutschen Tumorzentrum (WTZE), Universitätsklinikum Essen
    In: Der Urologe Jg. 46 (2007) Nr. 9, S. 1257 - 1260
    Online Volltext: dx.doi.org/
  • Schenck, Marcus; Börgermann, Christof; vom Dorp, Frank; Busch, Y.; Groneberg, M.; Wilker, B.; Keitsch, S.; Moyrer, S.; Schmid, Kurt Werner; Stuschke, Martin; Rübben, Herbert; Gulbins, Erich
    Identifikation der molekularen Grundlagen der Metastasierung zur Entwicklung neuer Therapiestrategien des metastasierten Prostatakarzinoms
    In: Der Urologe Jg. 46 (2007) Nr. 9, S. 1261 - 1262
    Online Volltext: dx.doi.org/
  • Schenck, Marcus; Börgermann, Christof; vom Dorp, Frank; Groneberg, M.; Busch, Y.; Carpinteiro, Alexander; Wilker, B.; Keitsch, S.; Moyrer, S.; Schmid, Kurt Werner; Stuschke, Martin; Rübben, Herbert; Gulbins, Erich
    Proapoptotische Antikörper als neue Tumortherapeutika
    In: Der Urologe Jg. 46 (2007) Nr. 9, S. 1262 - 1265
    Online Volltext: dx.doi.org/
  • Grassme, Heike; Riehle, Andrea; Gulbins, Erich
    Viele Wege führen in die Zelle : die Interaktion von Pathogenen mit humanen Wirtszellen
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 28 - 33
    Online Volltext (Open Access)

    • Abstracts

  • Bachmann, M.; Gulbins, Erich; Szabo, I.;
    Issue Information
    57th Annual Scientic Meeting of the European Society for Clinical Investigation, 07.-09-06.2023, Prague,
    In: European Journal of Clinical Investigation Jg. 53 (2023) Nr. S1, Special Issue: 57TH ANNUAL SCIENTIFIC MEETING – 7–9 June 2023, Prague, Czech Republic, 57ASM - 25
    Online Volltext: dx.doi.org/ (Open Access)
  • Westhölter, D; Schumacher, F; Wülfinghoff, N; Sutharsan, S; Strassburg, S; Kleuser, B; Horn, Peter A.; Reuter, S; Gulbins, Erich; Taube, Christian; Welsner, M;
    Elexacaftor tezacaftor ivacaftor therapy alters plasma sphingolipid profiles in people with cystic fibrosis
    ERS International Congress ; 4-6 September 2022, Barcelona, Spain and online,
    In: European Respiratory Journal (ERJ) (2022)
    Online Volltext: dx.doi.org/
  • Bhat, Owais M.; Yuan, Xinxu; Li, Guangbi; Camus, Sarah; Kukreja, Rakesh C.; Gulbins, Erich; Li, Pin-Lan
    Regulatory Role of Ceramide/mTOR Signaling in Exosome Secretion from Smooth Muscle Cells during Arterial Stiffening and Medial Calcification
    In: The FASEB Journal Jg. 34 (2020) Nr. S1,
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Weiwei; Wilson, Gregory; Bachmann, Magdalena; Wang, Jiang; Edwards, Michael; Szabo, Ildiko; Gulbins, Erich; Ahmad, Syed; Patel, Sameer;
    The role and mechanism of voltage-gated potassium channel, Kv1.3, in pancreatic ductal adenocarcinoma (PDAC)
    AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, USA,
    In: Cancer Research Jg. 80 (2020) Nr. Suppl. 16, S. 2742
    Online Volltext: dx.doi.org/
  • Becker, Katrin; Jaegers, J.; Fandrey, Joachim; Gulbins, Erich; Ferenz, Katja;
    Development of sphingosine-coupled oxygen carriers as novel drugs for treating pneumonia
    98th Meeting of the German Physiological Society, 30 September ‐ 2 October 2019, Ulm, Germany,
    In: Acta Physiologica Jg. 227 (2019) Nr. S719, B 04-10
    Online Volltext
  • Spassieva, S.; Becker, K. A.; Uerschels, A. K.; Goins, L. G.; Doolen, S.; Bielawski, J.; Bieberich, E.; Taylor, B.; Gulbins, Erich
    Docetaxel increases the levels of neurotoxic deoxysphingolipids in mice DRG
    In: Journal of Neurochemistry Jg. 150 (2019) Nr. S1, S. 245
    Online Volltext: dx.doi.org/ (Open Access)
  • Schuchman, Edward H.; Clancy, John; Dimango, Emily; Petrache, Irina; Gulbins, Erich; He, Xingxuan
    Novel use of the lysosomal enzyme acid ceramidase for the treatment of inflammatory lung diseases, including cystic fibrosis
    In: Molecular Genetics and Metabolism Jg. 114 (2015) Nr. 2, S. S104 - S105
    Online Volltext: dx.doi.org/
  • Schwartz, M.; Otto, Teresa; Brockmeier, U.; Lauterbach, S.; Metzen, Eric; Gulbins, Erich; Carpinteiro, Alexander; Scheerer, N.; Fandrey, Joachim;
    Effects of nitric oxide on hematogenous metastasis
    9th International Luebeck Conference Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Grow Factors, 13 - 15 July 2012, Lübeck, Germany,
    In: American Journal of Hematology Jg. 87 (2012) Nr. 10, S. E112 - E112
    Online Volltext: dx.doi.org/
  • Carpinteiro, Alexander; Keitsch, S.; Hessler, G.; Pozgajova, M.; Müller, Stefan; Dürig, Jan; Gulbins, Erich;
    Role of the acid sphingomyelinase in hematogenous tumor metastasis in a mouse model
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 46
    Online Volltext: dx.doi.org/
  • Carpinteiro, Alexander; Keitsch, S.; Möllmann, M.; Dührsen, Ulrich; Dürig, Jan; Gulbins, Erich;
    Role of the antigenic stimulation in the pathogenesis of chronic lymphocytic leukemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 39
    Online Volltext: dx.doi.org/

    • Beiträge in Sammelwerken und Tagungsbänden

  • Kleuser, Burkhard; Schumacher, Fabian; Gulbins, Erich
    New Therapeutic Options in Pulmonal Diseases : Sphingolipids and Modulation of Sphingolipid Metabolism
    In: Drug Delivery and Targeting / Schäfer-Korting, Monika; Schubert, Ulrich S. (Hrsg.) 2023, S. 289 - 312
    Online Volltext: dx.doi.org/
  • Carpinteiro, Alexander; Gulbins, Erich
    Analysis of lipids in ceramide-enriched membrane domains
    In: Lipid Rafts: Methods and Protocols / Bieberich, Erhard (Hrsg.) 2021, S. 207 - 213
    Online Volltext: dx.doi.org/
  • Neuber, Corinna; Schumacher, Fabian; Gulbins, Erich; Kleuser, Burkhard
    Mass Spectrometric Determination of Fatty Aldehydes Exemplified by Monitoring the Oxidative Degradation of (2E)-Hexadecenal in HepG2 Cell Lysates
    In: Lipidomics / Wood, Paul (Hrsg.) 2017, S. 147 - 158
    Online Volltext: dx.doi.org/
  • Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Kolesnick, Richard; Gulbins, Erich
    Acid Sphingomyelinase
    In: Sphingolipids: Basic Science and Drug Development / Gulbins, Erich; Petrache, Irena 2013, S. 77 - 88
    Online Volltext: dx.doi.org/
  • Grassmé, Heike; Riethmüller, Joachim; Gulbins, Erich
    Ceramide in cystic fibrosis
    In: Sphingolipids in Disease / Gulbins, Erich; Petrache, Irina 2013, S. 265 - 274
    Online Volltext: dx.doi.org/
  • Kornhuber, Johannes; Tripal, Philipp; Gulbins, Erich; Muehlbacher, Markus
    Functional inhibitors of acid sphingomyelinase (FIASMAs)
    In: Sphingolipids in Health and Disease / Gulbins, Erich; Petrache, Irena 2013, S. 169 - 186
    Online Volltext: dx.doi.org/
  • Mühle, C.; Reichel, M.; Gulbins, Erich; Kornhuber, J.
    Sphingolipids in psychiatric disorders and pain syndromes
    In: Sphingolipids in Disease / Gulbins, Erich; Petrache, Irina (Hrsg.) 2013, S. 431 - 456
    Online Volltext: dx.doi.org/
  • Imhäuser, Christian; Gulbins, Heike; Gulbins, Erich; Lipinski, Hans-Gerd
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