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Wiss. Mitarbeiterinnen/Mitarbeiter, Fachbereichsrat
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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Klinik für Anästhesiologie und Intensivmedizin
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Improving AI-Based Clinical Decision Support Systems and Their Integration Into Care From the Perspective of Experts : Interview Study Among Different StakeholdersIn: JMIR Medical Informatics (JMI), Jg. 13, 2025, e69688DOI (Open Access)
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Problems and Barriers Related to the Use of AI-Based Clinical Decision Support Systems : Interview StudyIn: Journal of Medical Internet Research (JMIR), Jg. 27, 2025, e63377DOI, Online Volltext (Open Access)
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User-Oriented Requirements for Artificial Intelligence–Based Clinical Decision Support Systems in Sepsis : Protocol for a Multimethod Research ProjectIn: JMIR Research Protocols, Jg. 14, 2025, e62704DOI, Online Volltext (Open Access)
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Divergent autoantibody and cytokine levels in COVID-19 sepsis patients influence survivalIn: Journal of Medical Virology, Jg. 96, 2024, Nr. 10, e29935DOI (Open Access)
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Biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2 trial) : study protocol for an international, prospective, randomised controlled multicentre trialIn: BMJ Open, Jg. 13, 2023, Nr. 3, S. e070240DOI (Open Access)
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Human cytomegalovirus seropositivity is associated with reduced patient survival during sepsisIn: Critical Care: The Online Intensive Care Journal, Jg. 27, 2023, Nr. 1, 417DOI (Open Access)
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The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with SepsisIn: Cells, Jg. 11, 2022, Nr. 19, 3020DOI (Open Access)
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Long-term mortality and outcome in hospital survivors of septic shock, sepsis, and severe infections : The importance of aftercareIn: PLoS ONE, Jg. 15, 2020, Nr. 2, e0228952DOI (Open Access)
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Major Adverse Kidney Events Are Associated with the Aquaporin 5 -1364A/C Promoter Polymorphism in Sepsis : A Prospective Validation StudyIn: Cells, Jg. 9, 2020, Nr. 4, 904DOI (Open Access)
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Mitochondrial dysfunction in sepsis is associated with diminished intramitochondrial TFAM despite its increased cellular expressionIn: Scientific Reports, Jg. 10, 2020, Nr. 1, S. 21029DOI (Open Access)
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Aquaporin 5 -1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress SyndromeIn: Anesthesiology, Jg. 130, 2019, Nr. 3, S. 404 – 413DOI (Open Access)
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DNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsisIn: Scientific Reports, Jg. 9, 2019, Nr. 1, 18511DOI (Open Access)
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Circulating miR-192 is a prognostic marker in patients with ischemic cardiomyopathyIn: Future Cardiology, Jg. 14, 2018, Nr. 4, S. 283 – 289
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Increased circulating microRNA-122 is associated with mortality and acute liver injury in the acute respiratory distress syndromeIn: BMC Anesthesiology, Jg. 18, 2018, S. 75DOI (Open Access)
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Increased circulating microrna-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteriaIn: PLoS ONE, Jg. 13, 2018, Nr. 5, S. e0197637DOI (Open Access)
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The aquaporin 5 -1364A/C promoter polymorphism impacts on resolution of acute kidney injury in pneumonia evoked ARDS.In: PLoS ONE, Jg. 13, 2018, Nr. 12, S. e0208582DOI (Open Access)
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Comparison of mortality prediction models in acute respiratory distress syndrome undergoing extracorporeal membrane oxygenation and development of a novel prediction score: the PREdiction of Survival on ECMO Therapy-Score (PRESET-Score).In: Critical Care: The Online Intensive Care Journal, Jg. 21, 2017, Nr. 1, S. 301DOI, Online Volltext (Open Access)
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Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS).In: International Journal of Molecular Sciences (IJMS), Jg. 18, 2017, Nr. 6DOI, Online Volltext (Open Access)
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Moxifloxacin monotherapy versus combination therapy in patients with severe community-acquired pneumonia evoked ARDSIn: BMC Anesthesiology, Jg. 17, 2017, Nr. 1, S. 78DOI (Open Access)
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AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration : a prospective laboratory and patient studyIn: Journal of Translational Medicine, Jg. 14, 2016, Nr. 1, 321DOI (Open Access)
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Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis : a prospective observational trialIn: BMC Anesthesiology, Jg. 16, 2016, Nr. 1, S. 61DOI (Open Access)
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Mitochondrial DNA : an endogenous trigger for immune paralysisIn: Anesthesiology, Jg. 124, 2016, Nr. 4, S. 923 – 933
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The Transcription Factor NMP4 Binds to the AQP5 Promoter and Is a Novel Transcriptional Regulator of the AQP5 GeneIn: DNA and Cell Biology, Jg. 35, 2016, Nr. 7, S. 322 – 327
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AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinomaIn: The Journal of Laryngology and Otology, Jg. 129, 2015, Nr. 6, S. 580 – 586
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Reply: PCR assay for pathogen detection in ventriculostomy-related meningitis in neurosurgery patients: unanswered questions?In: Infection - A Journal of Infectious Disease, Jg. 43, 2015, Nr. 2, S. 251 – 252
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Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic ShockIn: PLoS ONE, Jg. 9, 2014, Nr. 8, e104953DOI (Open Access)
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Value of multiplex PCR using cerebrospinal fluid for the diagnosis of ventriculostomy-related meningitis in neurosurgery patientsIn: Infection - A Journal of Infectious Disease, Jg. 42, 2014, Nr. 4, S. 621 – 627DOI (Open Access)
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An increased alveolar CD4 + CD25 + Foxp3 + T-regulatory cell ratio in acute respiratory distress syndrome is associated with increased 30-day mortalityIn: Intensive Care Medicine, Jg. 39, 2013, Nr. 10, S. 1743 – 1751DOI, Online Volltext (Open Access)
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Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulatedIn: Shock, Jg. 40, 2013, Nr. 5, S. 430 – 436
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Correlation of Aquaporin-1 Water Channel Protein Expression with Tumor Angiogenesis in Human AstrocytomaIn: Anticancer Research, Jg. 33, 2013, Nr. 2, S. 609 – 613
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Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patientsIn: Journal of Neuro-Oncology, Jg. 112, 2013, Nr. 2, S. 297 – 305
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Fulminant progressive thyroid cyst with tracheal compression - a case reportIn: Experimental and Clinical Endocrinology & Diabetes, Jg. 121, 2013, Nr. 3, S. P23
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Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: Prospective observational clinical and cellular studiesIn: Anesthesiology, Jg. 118, 2013, Nr. 6, S. 1426 – 1436
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The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.In: Anesthesiology, Jg. 118, 2013, Nr. 1, S. 123 – 133
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The functional Aquaporin 1 −783G/C-polymorphism is associated with survival in patients with glioblastoma multiformeIn: Journal of Surgical Oncology, Jg. 108, 2013, Nr. 7, S. 492 – 498
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Distinct proteasome subpopulations in the alveolar space of patients with the acute respiratory distress syndromeIn: Mediators of Inflammation, 2012, 204250DOI (Open Access)
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Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcomeIn: Critical Care: The Online Intensive Care Journal, Jg. 16, 2012, Nr. 4, S. R125DOI, Online Volltext (Open Access)
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Modern Methods for the Determination of Concentration of Antibiotics by Microdialysis in interstitial Fluid of Muscle and Subcutaneous Tissue in septic PatientsIn: Infection - A Journal of Infectious Disease, Jg. 40, 2012, Nr. Suppl. 1, S. 29
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Quantification of Regulatory T Cells in Septic Patients by Real-Time PCR–Based Methylation Assay and Flow CytometryIn: PLoS ONE, Jg. 7, 2012, Nr. 11, S. e49962DOI, Online Volltext (Open Access)
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Recurrent false alarm of extracorporeal membrane oxygenation at high noonIn: European Journal of Anaesthesiology EJA, Jg. 29, 2012, Nr. 12, S. 602 – 604
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The -1364A/C Aquaporin 5 Gene Promoter Polymorphism Is Not Associated with Menière’s DiseaseIn: ISRN Otolaryngology, 2012, S. 706896
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Whole blood impedance aggregometry as a biomarker for the diagnosis and prognosis of severe sepsisIn: Critical Care: The Online Intensive Care Journal, Jg. 16, 2012, S. R204DOI, Online Volltext (Open Access)
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Aquaporin 5 gene promoter -1364A/C polymorphism associated with 30-day survival in severe sepsisIn: Anesthesiology, Jg. 114, 2011, Nr. 4, S. 912 – 917DOI (Open Access)
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Association of the CC genotype of the regulatory BCL2 promoter polymorphism (−938C>A) with better 2-year survival in patients with glioblastoma multiformeIn: Journal of Neurosurgery (JNS), Jg. 114, 2011, Nr. 6, S. 1631 – 1639
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Comparison of Thrombelastometry with Simplified Acute Physiology Score II and Sequential Organ Failure Assessment Scores for the Prediction of 30-Day Survival : A Cohort StudyIn: Shock, Jg. 35, 2011, Nr. 4, S. 339 – 342DOI (Open Access)
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Role of the GNAS1 T393C polymorphism in patients with glioblastoma multiformeIn: Journal of Clinical Neuroscience, Jg. 18, 2011, Nr. 11, S. 1495 – 1499
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The NFKB1 promoter polymorphism (94ins/delATTG) alters nuclear translocation of NF-KB1 in monocytes following lipopolysaccharide stimulation and is associated with increased mortality in sepsisIn: Infection - A Journal of Infectious Disease, Jg. 39, 2011, Nr. Suppl. 2, S. 102
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Aquaporin 1 (AQP1) expression is a novel characteristic feature of a particularly aggressive subgroup of basal-like breast carcinomasIn: Breast Cancer Research and Treatment, Jg. 120, 2010, Nr. 1, S. 67 – 76
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Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiformeIn: Journal of Cancer Research and Clinical Oncology, Jg. 136, 2010, Nr. 9, S. 1423 – 1429
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Comparison of thromboelastometry with procalcitonin, interleukin 6, and C-reactive protein as diagnostic tests for severe sepsis in critically ill adultsIn: Critical Care: The Online Intensive Care Journal, Jg. 14, 2010, Nr. 5, S. R178DOI (Open Access)
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Gerinnungsfaktoren als Potenzielle Tumormarker bei Patienten mit Kopf-Hals-Karzinomen?In: Laryngo-Rhino-Otologie, Jg. 89, 2010, Nr. 10, S. 612 – 615
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Hemikolektomie bei Kolonischämie : Fallbericht von Schweinegrippe mit letalem VerlaufIn: Der Chirurg, Jg. 81, 2010, Nr. 9, S. 841 – 845DOI, Online Volltext (Open Access)
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Posttonsillectomy hemorrhage : Blame on surgeons or genes?In: Laryngoscope, Jg. 120, 2010, Nr. 9, S. 1784 – 1787
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Alveolar extracellular 20s proteasome in patients with acute respiratory distress syndromeIn: American Journal of Respiratory and Critical Care Medicine (AJRCCM), Jg. 179, 2009, Nr. 12, S. 1098 – 1106
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A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy menIn: Basic Research in Cardiology, Jg. 103, 2008, Nr. 6, S. 598 – 610
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Factor v Leiden mutation is associated with improved 30-day survival in patients with acute respiratory distress syndromeIn: Critical Care Medicine, Jg. 36, 2008, Nr. 6, S. 1776 – 1779
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Comparison of manual and automated nucleic acid extraction from whole-blood samplesIn: Journal of Clinical Laboratory Analysis, Jg. 21, 2007, Nr. 4, S. 244 – 248DOI (Open Access)
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Intravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthmaIn: Anesthesia and Analgesia, Jg. 104, 2007, Nr. 1, S. 168 – 172
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Molekularbiologische, funktionelle und phänotypische Charakterisierung eines genetischen Polymorphismus im Promotor des Gens AQP5Duisburg, Essen, 2009
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Vergleich der Elektronenstrahlcomputertomographie mit dem intervaskulären Ultraschall und der Koronarangiographie zur Erkennung von koronaratherosklerotischen Veränderungen auf SegmentebeneEssen, 2000