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Prof. Dr. med. Alexander Röth

Funktionen

  • , Klinik für Hämatologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Schleupner, Marie Carolin; Röth, Alexander; Adam, Luise; Sadok, Nadia; Toppe, Felicia; Lakomek, Antonia Klara; Wainwright, Sami; Voss, Noemi; Boosfeld, Lukas; Kaiser, Christina; Garvert, Julia; Lang, Stephan; Geisthoff, Urban; Droege, Freya
    Cobalamin and iron deficiency still presents a challenge in hereditary hemorrhagic telangiectasia
    In: Scientific Reports, Jg. 15, 2025, Nr. 1, 28463
    DOI (Open Access)
  • Nishimori, Hisakazu; Nakazawa, Hideyuki; Tamura, Shinobu; Uchida, Toshiki; Usuki, Kensuke; Szamosi, Johan; De Latour, Régis Peffault; Röth, Alexander; Panse, Jens
    Efficacy, Safety, and Quality of Life of Pegcetacoplan in Japanese Patients with Paroxysmal Nocturnal Hemoglobinuria Treated within the Phase 3 PEGASUS Trial
    In: Acta Haematologica, Jg. 148, 2025, Nr. 1, S. 22 – 35
    DOI (Open Access)
  • Cella, David; Hill, Quentin A.; Karaouni, Alia; Joly, Florence; Sourdille, Timothee; Shafer, Frank; Wardęcki, Marek; Kosinski, Mark; Röth, Alexander
    FACIT-Fatigue scale in patients with cold agglutinin disease : Psychometric validation and estimation of clinically meaningful change
    In: Frontiers in Hematology, Jg. 4, 2025, 1490130
    DOI (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Ademokun, Christine; Jang, Junho; Lozano, Maria Luisa; Ferreiras, David Valcarcel; Pascual-Izquierdo, Cristina; Chitnis, Shripad; Matviykiv, Sofiya; Vitaliti, Alessandra; Chen, Chi; Katsanou, Vasiliki; Chawla, Raghav; Al-Samkari, Hanny
    Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease : A Global Phase 2 Basket Clinical Trial
    In: American Journal of Hematology, 2025, in press
    DOI (Open Access)
  • Röth, Alexander; Borchert, Kersten; Dorn, Carla; Kleemiß, Moritz; Körper, Sixten; Mayer, Stephanie; Schafhausen, Philippe; Schrenk, Karin G.; Bramlage, Peter; Theis, Frauke
    Kälteagglutininerkrankung
    In: Die Innere Medizin, Jg. 66, 2025, Nr. 9, S. 986 – 996
    DOI (Open Access)
  • Tometten, Mareike; Beier, Fabian; Kirschner, Martin; Schumacher, Yannic; Walter, Jeanette; Vieri, Margherita; Kricheldorf, Kim; Röth, Alexander; Platzbecker, Uwe; Radsak, Markus; Schafhausen, Philippe; Corbacioglu, Selim; Höchsmann, Britta; Balabanov, Stefan; Hinze, Claas; Chromik, Jörg; Heuser, Michael; Kreuter, Michael; Wlodarski, Marcin W.; Elbracht, Miriam; Kurth, Ingo; Koschmieder, Steffen; Panse, Jens; Isfort, Susanne; Meyer, Robert; Brümmendorf, Tim H.
    Late-onset telomere biology disorders in adults: : clinical insights and treatment outcomes from a retrospective registry cohort
    In: Blood Advances, Jg. 9, 2025, Nr. 9, S. 2183 – 2191
    DOI (Open Access)
  • Risitano, Antonio M; Kulasekararaj, Austin G; Scheinberg, Phillip; Röth, Alexander; Han, Bing; Maciejewski, Jaroslaw P; Ueda, Yasutaka; de Castro, Carlos M; Di Bona, Eros; Fu, Rong; Zhang, Li; Griffin, Morag; Langemeijer, Saskia M C; Panse, Jens; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor A Q; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Chew, Lee Ping; Gaya, Anna; Huang, Wei-Han; Jang, Jun Ho; Kitawaki, Toshio; Kutlar, Abdullah; Notaro, Rosario; Pullarkat, Vinod; Schubert, Jörg; Terriou, Louis; Uchiyama, Michihiro; Lee, Lily Wong Lee; Yap, Eng-Soo; Frieri, Camilla; Marano, Luana; de Fontbrune, Flore Sicre; Gandhi, Shreyans; Trikha, Roochi; Alashkar, Ferras; Yang, Chen; Liu, Hui; Kelly, Richard J; Höchsmann, Britta; Lawniczek, Tomasz; Mahajan, Navin; Solar-Yohay, Susan; Kerloëguen, Cécile; Ferber, Philippe; Kumar, Rakesh; Wang, Zhixin; Thorburn, Christine; Maitra, Samopriyo; Li, Shujie; Verles, Aurelie; Dahlke, Marion; de Latour, Régis Peffault
    Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria : Final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors
    In: The Lancet Haematology, Jg. 12, 2025, Nr. 6, S. e414 – e430
    DOI
  • Panse, Jens; Han, Bing; Cermak, Jaroslav; Gonzalez Fernandez, Fernando Ataulfo; Gotoh, Akihiko; Kulasekararaj, Austin G.; Kyselova, Olena; Sahin, Fahri; Scheinberg, Phillip; Schrezenmeier, Hubert; Straetmans, Nicole; Ueda, Yasutaka; Chang, Alice C.; Gentile, Brittany; Stefani, Jennifer; Uguen, Marianne; Röth, Alexander
    Patient-reported outcomes in patients with paroxysmal nocturnal hemoglobinuria treated with crovalimab and approved C5 inhibitors in the phase III COMMODORE 2 and 1 studies
    In: Annals of Hematology, Jg. 104, 2025, Nr. 6, S. 3199 – 3212
    DOI (Open Access)
  • Cosson, Valérie; Fu, Rong; Kulasekararaj, Austin; Nishimura, Jun-Ichi; Panse, Jens; Röth, Alexander; Scheinberg, Phillip; Tong, Hongyan; Yoon, Sung-Soo; Beveridge, Leigh; Gotanda, Keisuke; Jaminion, Félix; Henrich, Andrea; Lundberg, Pontus; Shi, Dayu; Sreckovic, Sasha; Zhang, Yuchen; Zhang, Zilu; Benkali, Khaled; Buatois, Simon
    Pharmacokinetic characterization and exposure–response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria
    In: British Journal of Clinical Pharmacology (BJCP), Jg. 91, 2025, Nr. 5, S. 1479 – 1490
    DOI (Open Access)
  • Kulasekararaj, Austin; Brodsky, Robert; Schrezenmeier, Hubert; Griffin, Morag; Röth, Alexander; Piatek, Caroline; Ogawa, Masayo; Yu, Ji; Patel, Ami S.; Patel, Yogesh; Notaro, Rosario; Usuki, Kensuke; Kulagin, Alexander; Gualandro, Sandra; Füreder, Wolfgang; Peffault de Latour, Regis; Szer, Jeff; Lee, Jong Wook
    Ravulizumab demonstrates long-term efficacy, safety and favorable patient survival in patients with paroxysmal nocturnal hemoglobinuria
    In: Annals of Hematology, Jg. 104, 2025, Nr. 1, S. 81 – 94
    DOI (Open Access)
  • Fattizzo, Bruno; Röth, Alexander; Broome, Catherine M.; Khan, Umer; Wardęcki, Marek; Cordoba, Matias; Barcellini, Wilma
    COVID-19 vaccine safety and immunogenicity in patients with cold agglutinin disease receiving concomitant sutimlimab
    In: American Journal of Hematology, Jg. 99, 2024, Nr. 4, S. 789 – 791
    DOI (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Anderson Tvedt, Tor Henrik; Miyakawa, Yoshitaka; Kuter, David J.; Su, Jun; Jiang, Xiaoyu; Hobbs, William; Morales, Jaime; Shafer, Frank; Weitz, Ilene C.
    Correction to: Sutimlimab improves quality of life in patients with cold agglutinin disease : Results of patient-reported outcomes from the CARDINAL study
    In: Annals of Hematology, Jg. 103, 2024, Nr. 5, S. 1803
    DOI (Open Access)
  • Poppenborg, Friederike; Röth, Alexander; Yamamoto, Raina; Reinhardt, Hans Christian; Alashkar, Ferras
    Crizanlizumab in adult patients with sickle cell disease: : a retrospective German analysis
    In: Frontiers in Hematology, Jg. 3, 2024, 1374181
    DOI, Online Volltext (Open Access)
  • Röth, Alexander; Kulasekararaj, Austin G.; Scheinberg, Phillip; Nishimura, Jun-ichi
    Crovalimab in the paroxysmal nocturnal hemoglobinuria treatment landscape
    In: Immunotherapy, Jg. 16, 2024, Nr. 20-22, S. 1185 – 1196
    DOI (Open Access)
  • Dingli, David; De Castro III, Carlos; Koprivnikar, Jamie; Kulasekararaj, Austin; Maciejewski, Jaroslaw; Mulherin, Brian; Panse, Jens; Pullarkat, Vinod; Röth, Alexander; Shammo, Jamile; Terriou, Louis; Weitz, Ilene; Yermilov, Irina; Gibbs, Sarah; Broder, Michael; Beenhouwer, David; Kuter, David
    Expert consensus on the management of pharmacodynamic breakthrough-hemolysis in treated paroxysmal nocturnal hemoglobinuria
    In: Hematology, Jg. 29, 2024, Nr. 1, 2329030
    DOI (Open Access)
  • Kuter, David J.; Piatek, Caroline; Röth, Alexander; Siddiqui, Asif; Numerof, Robert P.; Dummer, Wolfgang
    Fostamatinib for warm antibody autoimmune hemolytic anemia : Phase 3, randomized, double-blind, placebo-controlled, global study (FORWARD)
    In: American Journal of Hematology, Jg. 99, 2024, Nr. 1, S. 79 – 87
    DOI (Open Access)
  • Schorb, Elisabeth; Isbell, Lisa Kristina; Kerkhoff, Andrea; Mathas, Stephan; Braulke, Friederike; Egerer, Gerlinde; Röth, Alexander; Schliffke, Simon; Borchmann, Peter; Brunnberg, Uta; Kroschinsky, Frank; Möhle, Robert; Rank, Andreas; Wellnitz, Dominique; Kasenda, Benjamin; Pospiech, Lisa; Wendler, Julia; Scherer, Florian; Deckert, Martina; Henkes, Elina; von Gottberg, Philipp; Gmehlin, Dennis; Backenstraß, Matthias; Jensch, Antje; Burger-Martin, Elvira; Grishina, Olga; Fricker, Heidi; Malenica, Natalie; Orbán, András; Duyster, Justus; Ihorst, Gabriele; Finke, Juergen; Illerhaus, Gerald
    High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA) : A single-arm, phase 2 trial
    In: The Lancet Haematology, Jg. 11, 2024, Nr. 3, S. e196 – e205
    DOI
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Jayawardene, Deepthi; Srivastava, Shruti; Wardęcki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.; D’Sa, Shirley
    Long-term efficacy and safety of continued complement C1s inhibition with sutimlimab in cold agglutinin disease : CADENZA study Part B
    In: eClinicalMedicine, Jg. 74, 2024, 102733
    DOI, Online Volltext (Open Access)
  • Peffault de Latour, Régis; Röth, Alexander; Kulasekararaj, Austin G.; Han, Bing; Scheinberg, Phillip; Maciejewski, Jaroslaw P.; Ueda, Yasutaka; de Castro, Carlos M.; Di Bona, Eros; Fu, Rong; Zhang, Li; Griffin, Morag; Langemeijer, Saskia M.C.; Panse, Jens; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor A.Q.; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Chew, Lee Ping; Gaya, Anna; Huang, Wei-Han; Jang, Jun Ho; Kitawaki, Toshio; Kutlar, Abdullah; Notaro, Rosario; Pullarkat, Vinod; Schubert, Jörg; Terriou, Louis; Uchiyama, Michihiro; Lee, Lily Wong Lee; Yap, Eng-Soo; de Fontbrune, Flore Sicre; Marano, Luana; Alashkar, Ferras; Gandhi, Shreyans; Trikha, Roochi; Yang, Chen; Liu, Hui; Kelly, Richard J.; Höchsmann, Britta; Kerloeguen, Cécile; Banerjee, Partha; Levitch, Rafael; Kumar, Rakesh; Wang, Zhixin; Thorburn, Christine; Maitra, Samopriyo; Li, Shujie; Verles, Aurelie; Dahlke, Marion; Risitano, Antonio M.
    Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria
    In: The New England Journal of Medicine, Jg. 390, 2024, Nr. 11, S. 994 – 1008
    DOI (Open Access)
  • Wilson, Koo; Rich, Carly; Hakimi, Zalmai; Horneff, Regina; Fishman, Jesse; Mellor, Jennifer; Earl, Lucy; Taylor, Yasmin; Simons, Alice; Conyers, Joe; Mulherin, Brian; Majerus, Elaine; Röth, Alexander
    Pegcetacoplan in paroxysmal nocturnal haemoglobinuria : Its use, its clinical effectiveness, and its influence on health-related quality of life and productivity
    In: European Journal of Haematology, Jg. 112, 2024, Nr. 4, S. 516 – 529
    DOI (Open Access)
  • Röth, Alexander; He, Guangsheng; Tong, Hongyan; Lin, Zenghua; Wang, Xiaoqin; Chai-Adisaksopha, Chatree; Lee, Je-Hwan; Brodsky, Andres; Hantaweepant, Chattree; Dumagay, Teresita E.; Demichelis-Gómez, Roberta; Rojnuckarin, Ponlapat; Sun, Jing; Höglund, Martin; Jang, Jun Ho; Gaya, Anna; Silva, Fernando; Obara, Naoshi; Kelly, Richard J.; Beveridge, Leigh; Buatois, Simon; Chebon, Sammy; Gentile, Brittany; Lundberg, Pontus; Sreckovic, Sasha; Nishimura, Jun-ichi; Risitano, Antonio; Han, Bing
    Phase 3 randomized COMMODORE 2 trial : Crovalimab versus eculizumab in patients with paroxysmal nocturnal hemoglobinuria naive to complement inhibition
    In: American Journal of Hematology, Jg. 99, 2024, Nr. 9, S. 1768 – 1777
    DOI (Open Access)
  • de Latour, Régis Peffault; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; Castro, Carlos de; Nishimori, Hisakazu; Al-Adhami, Mohammed; Deschatelets, Pascal; Francois, Cedric; Risitano, Antonio; Hillmen, Peter
    Plain language summary : treatment of paroxysmal nocturnal hemoglobinuria with pegcetacoplan for 48 weeks (PEGASUS study)
    In: Future Rare Diseases, Jg. 4, 2024, Nr. 1, 2340267
    DOI (Open Access)
  • Patriquin, Christopher J.; Bogdanovic, Andrija; Griffin, Morag; Kelly, Richard J.; Maciejewski, Jaroslaw P.; Mulherin, Brian; Peffault de Latour, Régis; Röth, Alexander; Selvaratnam, Veena; Szer, Jeffrey; Al-Adhami, Mohammed; Horneff, Regina; Tan, Lisa; Yeh, Michael; Panse, Jens
    Safety and Efficacy of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria over 48 Weeks : 307 Open-Label Extension Study
    In: Advances in Therapy, Jg. 41, 2024, Nr. 5, S. 2050 – 2069
    DOI (Open Access)
  • Röth, Alexander; Fu, Rong; He, Guangsheng; Alzahrani, Hazzaa; Chou, Sheng-Chieh; Hicheri, Yosr; Kaźmierczak, Maciej; Recova, Viviane Lacorte; Uchiyama, Michihiro; Vladareanu, Ana-Maria; Beveridge, Leigh; Buatois, Simon; Buri, Muriel; Compagno, Nicolo; Shi, Dayu; Balachandran, Nadiesh; Sreckovic, Sasha; Scheinberg, Phillip
    Safety of Crovalimab Versus Eculizumab in Patients With Paroxysmal Nocturnal Haemoglobinuria (PNH) : Pooled Results From the Phase 3 COMMODORE Studies
    In: European Journal of Haematology, Jg. 114, 2024, Nr. 2, S. 373 – 382
    DOI (Open Access)
  • D'Sa, Shirley; Vos, Josephine M. I.; Barcellini, Wilma; Wardęcki, Marek; Perrin, Laurent; Barker, Graham; Zilberstein, Moshe; Storek, Michael; Chow, Timothy; Röth, Alexander
    Safety, tolerability, and activity of the active C1s antibody riliprubart in cold agglutinin disease : A phase 1b study
    In: Blood, Jg. 143, 2024, Nr. 8, S. 713 – 720
    DOI (Open Access)
  • Röth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Anderson Tvedt, Tor Henrik; Yamaguchi, Masaki; Murakhovskaya, Irina; Lee, Michelle; Shafer, Frank; Wardęcki, Marek; Jayawardene, Deepthi; Yoo, Ronnie; Msihid, Jerome; Weitz, Ilene C.
    Sustained improvements in patient-reported outcomes after long-term sutimlimab in patients with cold agglutinin disease : results from the CADENZA study open-label extension
    In: eClinicalMedicine, Jg. 74, 2024, 102732
    DOI, Online Volltext (Open Access)
  • Kulasekararaj, Austin G.; Kuter, David J.; Griffin, Morag; Weitz, Ilene C.; Röth, Alexander
    Biomarkers and laboratory assessments for monitoring the treatment of patients with paroxysmal nocturnal hemoglobinuria : Differences between terminal and proximal complement inhibition
    In: Blood Reviews, Jg. 59, 2023, 101041
    DOI (Open Access)
  • Röth, Alexander; Ichikawa, Satoshi; Ito, Yoshikazu; Kim, Jin Seok; Nagy, Zsolt; Obara, Naoshi; Panse, Jens; Schrezenmeier, Hubert; Sica, Simona; Soret, Juliette; Usuki, Kensuke; Yoon, Sung-Soo; Balachandran, Nadiesh; Buri, Muriel; Lundberg, Pontus; Patel, Himika; Shinomiya, Kenji; Sostelly, Alexandre; Nishimura, Jun-ichi
    Crovalimab treatment in patients with paroxysmal nocturnal haemoglobinuria : Long-term results from the phase I/II COMPOSER trial
    In: European Journal of Haematology, Jg. 111, 2023, Nr. 2, S. 300 – 310
    DOI (Open Access)
  • Terriou, Louis; Lee, Jong Wook; Forsyth, Cecily; Griffin, Morag; Szer, Jeff; Röth, Alexander; Gustovic, Philippe; Metzger, Jesse; Patel, Ami S.; Patriquin, Christopher J.
    Long-term effectiveness of eculizumab: Data from the International PNH Registry
    In: European Journal of Haematology, Jg. 111, 2023, Nr. 5, S. 796 – 804
    DOI (Open Access)
  • Versmold, Katharina; Alashkar, Ferras; Raiser, Carina; Ofori-Asenso, Richard; Xu, Tao; Liu, Yutong; Katz, Pablo; Shang, Aijing; Röth, Alexander
    Long-term outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab in a real-world setting
    In: European Journal of Haematology, Jg. 111, 2023, Nr. 1, S. 84 – 95
    DOI (Open Access)
  • Röth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Tvedt, Tor Henrik Anderson; Miyakawa, Yoshitaka; D’Sa, Shirley; Cella, David; Bozzi, Sylvie; Jayawardene, Deepthi; Yoo, Ronnie; Shafer, Frank; Wardecki, Marek; Weitz, Ilene C.; D’Sa, Shirley
    Long-term sutimlimab improves quality of life for patients with cold agglutinin disease : CARDINAL 2-year follow-up
    In: Blood Advances, Jg. 7, 2023, Nr. 19, S. 5890 – 5897
    DOI (Open Access)
  • Nishimura, Jun-ichi; Soubret, Antoine; Arase, Noriko; Buatois, Simon; Hotta, Masaki; Charoin, Jean-Eric; Ito, Yoshikazu; Sreckovic, Sasha; Takamori, Hiroyuki; Bucher, Christoph; Ueda, Yasutaka; Hernández-Sánchez, Jules; Gotanda, Keisuke; Jordan, Gregor; Shinomiya, Kenji; Ramos, Julia; Kim, Jin Seok; Panse, Jens; de Latour, Régis Peffault; Röth, Alexander; Morii, Eiichi; Schrezenmeier, Hubert; Isaka, Yoshitaka; Sica, Simona; Kanakura, Yuzuru; Yoon, Sung-Soo; Kinoshita, Taroh; Paz-Priel, Ido; Sostelly, Alexandre
    Mitigating Drug–Target–Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors
    In: Clinical Pharmacology & Therapeutics, Jg. 113, 2023, Nr. 4, S. 904 – 915
    DOI (Open Access)
  • Griffin, Morag; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Hillmen, Peter; Kiladjian, Jean-Jacques; Castro, Carlos De; Nishimori, Hisakazu; Tan, Lisa; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Ajayi, Temitayo; Risitano, Antonio; De La Tour, Régis Peffault
    Plain language summary of PEGASUS, a study comparing pegcetacoplan with eculizumab for 16 weeks in people with paroxysmal nocturnal hemoglobinuria
    In: Future Rare Diseases, Jg. 3, 2023, Nr. 3, FRD42
    DOI (Open Access)
  • Höchsmann, Britta; Peffault de Latour, Regis; Hill, Anita; Röth, Alexander; Devos, Timothy; Patriquin, Christopher J.; Chou, Wen-Chien; Jain, Deepak; Zu, Ke; Wu, Chuntao; Lee, Jong Wook
    Risk factors for thromboembolic events in patients with paroxysmal nocturnal hemoglobinuria (PNH) : a nested case–control study in the International PNH Registry
    In: Annals of Hematology, Jg. 102, 2023, Nr. 11, S. 2979 – 2988
    DOI (Open Access)
  • Broome, Catherine M.; Röth, Alexander; Kuter, David J.; Scully, Marie; Smith, Roy; Wang, Jennifer; Reuter, Caroline; Hobbs, William; Daak, Ahmed
    Safety and efficacy of classical complement pathway inhibition with sutimlimab in chronic immune thrombocytopenia
    In: Blood Advances, Jg. 7, 2023, Nr. 6, S. 987 – 996
    DOI (Open Access)
  • Röth, Alexander; Barcellini, Wilma; D'Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M.; Michel, Marc; Kuter, David J.; Jilma, Bernd; Tvedt, Tor Henrik Anderson; Weitz, Ilene C.; Yoo, Ronnie; Jayawardene, Deepthi; Vagge, Deepthi S.; Kralova, Katarina; Shafer, Frank; Wardȩcki, Marek; Lee, Michelle; Berentsen, Sigbjørn
    Sustained inhibition of complement C1s with sutimlimab over 2 years in patients with cold agglutinin disease
    In: American Journal of Hematology, Jg. 98, 2023, Nr. 8, S. 1246 – 1253
    DOI (Open Access)
  • Röth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Tvedt, Tor Henrik Anderson; Yamaguchi, Masaki; Lee, Michelle; Shafer, Frank; Wardęcki, Marek; Jiang, Xiaoyu; Patel, Parija; Joly, Florence; Weitz, Ilene C.
    Sutimlimab provides clinically meaningful improvements in patient-reported outcomes in patients with cold agglutinin disease : Results from the randomised, placebo-controlled, Phase 3 CADENZA study
    In: European Journal of Haematology, Jg. 110, 2023, Nr. 3, S. 280 – 288
    DOI (Open Access)
  • Röth, Alexander; Bertram, Stefanie; Schroeder, Thomas; Haverkamp, Thomas; Voigt, Sebastian; Holtkamp, Caroline; Klump, Hannes; Wörmann, Bernhard; Reinhardt, Hans Christian; Alashkar, Ferras
    Acquired aplastic anemia following SARS-CoV-2 vaccination
    In: European Journal of Haematology, Jg. 109, 2022, Nr. 2, S. 186 – 194
    DOI (Open Access)
  • Röth, Alexander; Barcellini, Wilma; D'Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M.; Michel, Marc; Kuter, David J.; Jilma, Bernd; Tvedt, Tor Henrik Anderson; Weitz, Ilene C.; Patel, Parija; Jiang, Xiaoyu; Reuter, Caroline; Su, Jun; Shafer, Frank; Lee, Michelle; Berentsen, Sigbjørn; D’Sa, Shirley; Berentsen, Sigbjorn
    Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease : CARDINAL study 1-year interim follow-up results
    In: Haematologica / The Hematology Journal, Jg. 107, 2022, Nr. 7, S. 1698 – 1702
    DOI (Open Access)
  • Röth, Alexander; Fryzek, Jon; Jiang, Xiaohui; Reichert, Heidi; Patel, Parija; Su, Jun; Morales Arias, Jaime; Broome, Catherine M.
    Complement-mediated hemolysis persists year round in patients with cold agglutinin disease
    In: Transfusion, Jg. 62, 2022, Nr. 1, S. 51 – 59
    DOI (Open Access)
  • Nishimura, Jun-ichi; Usuki, Kensuke; Ramos, Julia; Ichikawa, Satoshi; Buri, Muriel; Kiialainen, Anna; Sostelly, Alexandre; Peffault de Latour, Régis; Paz-Priel, Ido; Röth, Alexander
    Crovalimab for treatment of patients with paroxysmal nocturnal haemoglobinuria and complement C5 polymorphism : Subanalysis of the phase 1/2 COMPOSER study
    In: British Journal of Haematology, 2022
    DOI (Open Access)
  • Ferreri, Andrés J. M.; Cwynarski, Kate; Pulczynski, Elisa; Fox, Christopher P.; Schorb, Elisabeth; Celico, Claudia; Falautano, Monica; Nonis, Alessandro; La Rosée, Paul; Binder, Mascia; Fabbri, Alberto; Ilariucci, Fiorella; Krampera, Mauro; Röth, Alexander; Hemmaway, Claire; Johnson, Peter W.; Linton, Kim M.; Pukrop, Tobias; Gørløv, Jettes Sønderskov; Balzarotti, Monica; Hess, Georg; Keller, Ulrich; Stilgenbauer, Stephan; Panse, Jense; Tucci, Alessandra; Orsucci, Lorella; Pisani, Francesco; Zanni, Manuela; Krause, Stefan W.; Schmoll, Hans J.; Hertenstein, Bernd; Rummel, Mathias; Smith, Jeffery; Thurner, Lorenz; Cabras, Giuseppina; Pennese, Elsa; Ponzoni, Maurilio; Deckert, Martina; Politi, Letterio S.; Finke, Jurgen; Ferranti, Antonella; Cozens, Kelly; Burger, Elvira; Ielmini, Nicoletta; Cavalli, Franco; Zucca, Emanuele; Illerhaus, Gerald; IELSG32 study investigators
    Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma : 7-year results of the IELSG32 randomized trial
    In: Leukemia, Jg. 36, 2022, Nr. 7, S. 1870 – 1878
    DOI
  • Alashkar, Ferras; Klump, Hannes; Lange, Cara Paulina; Proske, Pia; Schüssler, Maximilian; Yamamoto, Raina; Carpinteiro, Alexander; Berliner, Christoph Alexander; Schlosser, Thomas Wilfried; Röth, Alexander; Reinhardt, Hans Christian
    Luspatercept, a two‐edged sword in beta‐thalassemia‐associated paravertebral extramedullary hematopoietic masses (EHMs)
    In: European Journal of Haematology, Jg. 109, 2022, Nr. 6, S. 664 – 671
    DOI (Open Access)
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    Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis : An open-label, single-arm, phase 2, proof-of-concept trial
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    Long-term outcome of a randomized controlled study in patients with newly diagnosed severe aplastic anemia treated with antithymocyte globulin and cyclosporine, with or without granulocyte colony-stimulating factor : A Severe Aplastic Anemia Working Party Trial from the European Group of Blood and Marrow Transplantation
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    Aortic thrombosis leading to the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Oncology Research and Treatment, Jg. 39, 2016, Nr. Suppl. 3, S. 62 – 62
  • Socié, G; Schrezenmeier, H; Muus, P; Lisukov, I; Röth, Alexander; Kulasekararaj, A; Lee, J W; Araten, D; Hill, A; Brodsky, R; Urbano-Ispizua, A; Szer, J; Wilson, A; Hillmen, P
    Changing prognosis in paroxysmal nocturnal haemoglobinuria disease subcategories : an analysis of the International PNH Registry
    In: Internal Medicine Journal, Jg. 46, 2016, Nr. 9, S. 1044 – 1053
    DOI
  • Illerhaus, Gerald; Kasenda, Benjamin; Ihorst, Gabriele; Egerer, Gerlinde; Lamprecht, Monika; Keller; Wolf, Hans-Heinrich; Hirt, Carsten; Stilgenbauer, Stephan; Binder, Mascha; Hau, Peter; Edinger, Matthias; Frickhofen, Norbert; Bentz, Martin; Möhle, Robert; Röth, Alexander; Pfreundschuh, Michael; von Baumgarten, Louisa; Deckert, Martina; Hader, Claudia; Fricker, Heidi; Valk, Elke; Schorb, Elisabeth; Fritsch, Kristina; Finke, Jürgen
    High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma : A prospective, single-arm, phase 2 trial
    In: The Lancet Haematology, Jg. 3, 2016, Nr. 8, S. e388 – e397
    DOI
  • Alashkar, Ferras; Dührsen, Ulrich; Röth, Alexander
    Horse anti-thymocyte globulin and eculizumab as concomitant therapeutic approach in an aplastic paroxysmal nocturnal hemoglobinuria patient : go or no-go?
    In: European Journal of Haematology, Jg. 97, 2016, Nr. 4, S. 403 – 405
    DOI
  • Farsijani, N. M.; Dührsen, Ulrich; Röth, Alexander
    Infection control with granulocyte transfusions in very severe aplastic anemia (VSAA)
    In: Oncology Research and Treatment, Jg. 39 3, 2016, S. 62
  • Sellmann, Ludger; Scholtysik, Rene; de Beer, Dirk; Eisele, Lewin; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Düring, Jan; Röth, Alexander; Baerlocher, Gabriele
    Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia
    In: Leukemia and Lymphoma, Jg. 57, 2016, Nr. 3, S. 590 – 595
    DOI
  • Röth, Alexander; Bommer, M.; Huttmann, A.; Herich-Terhurne, D.; Kuklik, Nils; Lenz, V.; Schrezenmeier, H.; Dührsen, Ulrich
    The terminal complement inhibitor eculizumab in Cold Agglutinin Disease (CAD) : A prospective phase II trial (DECADE Trial)
    In: Oncology Research and Treatment, Jg. 39, 2016, Nr. Suppl. 3, S. 138 – 138
  • Röth, Alexander; Bommer, Martin; Hüttmann, Andreas; Herich-Terhurne, Dörte; Kuklik, Nils; Lenz, Veronika; Schrezenmeier, Hubert; Dührsen, Ulrich
    Complement Inhibition with Eculizumab in Patients with Cold Agglutinin Disease (CAD) : Results from a Prospective Phase II Trial (DECADE Trial)
    In: Blood, Jg. 126, 2015, Nr. 23, S. 274
    DOI, Online Volltext
  • Kelly, Richard J; Höchsmann, Britta; Szer, Jeff; Kulasekararaj, Austin; de Guibert, Sophie; Röth, Alexander; Weitz, Ilene C; Armstrong, Elina; Risitano, Antonio M; Patriquin, Christopher J; Terriou, Louis; Muus, Petra; Hill, Anita; Turner, Michelle P; Schrezenmeier, Hubert; Peffault de Latour, Regis
    Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria
    In: The New England Journal of Medicine, Jg. 373, 2015, Nr. 11, S. 1032 – 1039
    DOI (Open Access)
  • Geisthoff, Urban; Nguyen, Ha-Long; Röth, Alexander; Seyfert, Ulrich
    How to manage patients with hereditary haemorrhagic telangiectasia
    In: British Journal of Haematology, Jg. 171, 2015, Nr. 4, S. 443 – 452
    DOI
  • Röth, Alexander; Alashkar, Ferras; Herich-Terhürne, Dörte; Dührsen, Ulrich
    Paroxysmal nocturnal haemoglobinuria : to prednisone or not to prednisone? A case report of a patient previously treated with steroids for 15 yrs and significant response on eculizumab
    In: European Journal of Haematology, Jg. 95, 2015, Nr. 2, S. 177 – 180
    DOI
  • Kreher, Stephan; Strehlow, Felicitas; Martus, Peter; Roth, Patrick; Hertenstein, Bernd; Röth, Alexander; Birnbaum, Tobias; Griesinger, Frank; Rauch, Michael; Kanz, Lothar; Thiel, Eckhard; Weller, Michael; Korfel, Agnieszka
    Prognostic impact of intraocular involvement in primary CNS lymphoma : experience from the G-PCNSL-SG1 trial
    In: Annals of Hematology, Jg. 94, 2015, Nr. 3, S. 409 – 414
    DOI
  • Korfel, Agnieszka; Thiel, Eckhard; Martus, Peter; Möhle, Robert; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Mergenthaler, Hans G; Junghanß, Christian; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Roth, Patrick; Bamberg, Michael; Pietsch, Torsten; Weller, Michael
    Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma
    In: Neurology, Jg. 84, 2015, Nr. 12, S. 1242 – 1248
    DOI (Open Access)
  • Baerlocher, Gabriela M; Oppliger Leibundgut, Elisabeth; Ottmann, Oliver G; Spitzer, Gary; Odenike, Olatoyosi; McDevitt, Michael A; Röth, Alexander; Daskalakis, Michael; Burington, Bart; Stuart, Monic; Snyder, David S
    Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia
    In: The New England Journal of Medicine, Jg. 373, 2015, Nr. 10, S. 920 – 928
    DOI (Open Access)
  • Schubert, Jörg; Röth, Alexander
    Update on paroxysmal nocturnal haemoglobinuria : On the long way to understand the principles of the disease
    In: European Journal of Haematology, Jg. 94, 2015, Nr. 6, S. 464 – 473
    DOI
  • Weller, Michael; Thiel, Eckhard; Martus, Peter; Möhle, Robert; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Mergenthaler, Hans-Günter; Junghanss, Christian; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Pietsch, Torsten; Roth, Patrick; Bamberg, Michael; Korfel, Agnieszka; Mergenthaler, H.-G.
    At-59-high-dose MTX-based chemotherapy for primary CNS lymphoma : with or without whole brain radiotherapy? : final analysis of G-PCNSL-SG-1
    In: Neuro-Oncology, Jg. 16, 2014, Nr. Suppl.5, S. v21 – v22
    DOI
  • Röth, Alexander
    Selten aber wichtig : Paroxysmale nächtliche Hämoglobinurie (PNH)
    In: Nieren- und Hochdruckkrankheiten, Jg. 43, 2014, Nr. 6, S. 281 – 285
  • Goethert, JoachimRud; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Zesewitz, Marie-Loui; Sellmann, Ludger; Röth, Alexander; Pircher, Hanspeter; Dührsen, Ulrich; Dürig, Jan
    Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotype
    In: Cancer Immunology, Immunotherapy, Jg. 62, 2013, Nr. 11, S. 1697 – 1709
    DOI
  • Khandanpour, Cyrus; Dührsen, Ulrich; Röth, Alexander
    Hand-foot syndrome : common presentation in an uncommon situation
    In: European Journal of Haematology, Jg. 91, 2013, Nr. 5, S. 472
    DOI
  • Hillmen, Peter; Muus, Petra; Röth, Alexander; Elebute, Modupe O.; Risitano, Antonio M.; Schrezenmeier, Hubert; Szer, Jeffrey; Browne, Paul; Maciejewski, Jaroslaw P.; Schubert, Jörg; Urbano-Ispizua, Alvaro; de Castro, Carlos; Socié, Gérard; Brodsky, Robert A.
    Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria
    In: British Journal of Haematology, Jg. 162, 2013, Nr. 1, S. 62 – 73
    DOI (Open Access)
  • Korfel, Agnieszka; Elter, Thomas; Thiel, Eckhard; Hänel, Matthias; Möhle, Robert; Schroers, Roland; Reiser, Marcel; Dreyling, Martin; Eucker, Jan; Scholz, Christian; Metzner, Bernd; Röth, Alexander; Birkmann, Josef; Schlegel, Uwe; Martus, Peter; Illerhaus, Gerard; Fischer, Lars
    Phase II study of central nervous system (CNS)-directed chemotherapy including high-dose chemotherapy with autologous stem cell transplantation for CNS relapse of aggressive lymphomas
    In: Haematologica / The Hematology Journal, Jg. 98, 2013, Nr. 3, S. 364 – 370
    DOI (Open Access)
  • Föhring, D.; Viala, A.; Dührsen, Ulrich; Röth, Alexander
    Successful treatment of a patient with refractory aquired hemophilia A (AHA) lacking aPTT prolongation with rituximab and intravenous cyclophosphamide
    In: Onkologie, Jg. 36, 2013, Nr. Suppl. 7, S. 243
  • Oppliger Leibundgut, Elisabeth; Rogenmoser-Dissler, Daniela; de Beer, Dirk; Porret, Naomi A.; Zibellini, Silvia; Dürig, Jan; Röth, Alexander; Klingbiel, Dirk; Baerlocher, Gabriela M.
    CLLU1 expression distinguishes chronic lymphocytic leukemia from other mature B-cell neoplasms
    In: Leukemia Research, Jg. 36, 2012, Nr. 9, S. 1204 – 1207
    DOI
  • Johansson, Patricia; Metz, Klaus; Dührsen, Ulrich; Röth, Alexander
    Chronic lymphocytic leukemia gone osteolytic : a case report
    In: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 217 – 218
  • Röth, Alexander; Schmücker, U.; Tokareva, O.; Preising, N.; Hock, C.; Dührsen, Ulrich
    Fate of GPI-deficient clones in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) : a retrospective analysis
    In: Onkologie, Jg. 35, 2012, Nr. 6, S. 24
  • Baerlocher, Gabriela M.; Leibundgut, Elisabeth O.; Ayran, Christina; Blaney, Martha; Burington, Bart; Morfeld, Dianne; Odenike, Olatoyosi; Ottman, Oliver; Reddy, Anita; Röth, Alexander; Spitzer, Gary; Stuart, Monic J.; Verstovsek, Srdan; Snyder, David S.
    Imetelstat Rapidly Induces and Maintains Substantial Hematologic and Molecular Responses in Patients with Essential Thrombocythemia (ET) Who Are Refractory or Intolerant to Prior Therapy : Preliminary Phase II Results
    In: Blood, Jg. 120, 2012, Nr. 21
  • Roth, Patrick; Martus, Peter; Kiewe, Philipp; Möhle, Robert; Klasen, Hermann Ayke; Rauch, Michael; Röth, Alexander; Kaun, Stephan; Thiel, Eckhard; Korfel, Agnieszka; Weller, Michael
    Outcome of elderly patients with primary CNS lymphoma in the G-PCNSL-SG-1 trial
    In: Neurology, Jg. 79, 2012, Nr. 9, S. 890 – 896
    DOI
  • Korfel, Agnieszka; Weller, Michael; Martus, Peter; Roth, Patrick; Klasen, Hermann Ayke; Röth, Alexander; Rauch, Michael; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Leithäuser, Malte; Birnbaum, Tobias; Kirchen, Heinz; Mergenthaler, Hans-Günther; Schubert, Jan; Berdel, Wolfgang; Birkmann, Josef; Hummel, Michael; Thiel, Eckhard; Fischer, Lars
    Prognostic impact of meningeal dissemination in primary CNS lymphoma (PCNSL) : experience from the G-PCNSL-SG1 trial
    In: Annals of Oncology, Jg. 23, 2012, Nr. 9, S. 2374 – 2380
    DOI (Open Access)
  • Marsh, Judith C.; Bacigalupo, Andrea; Schrezenmeier, Hubert; Tichelli, Andre; Risitano, Antonio M.; Passweg, Jakob R.; Killick, Sally B.; Warren, Alan J.; Foukaneli, Theodora; Aljurf, Mahmoud; Al-Zahrani, H. A.; Schafhausen, Philip; Roth, Alexander; Franzke, Anke; Brummendorf, Tim H.; Dufour, Carlo; Oneto, Rosi; Sedgwick, Philip; Barrois, Alain; Kordasti, Shahram; Elebute, Modupe O.; Mufti, Ghulam J.; Socie, Gerard
    Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party
    In: Blood, Jg. 119, 2012, Nr. 23, S. 5391 – 5396
    DOI
  • Illerhaus, Gerald; Fritsch, Kristina; Egerer, G.; Lamprecht, M.; von Bubnoff, Niklas; Wolf, H. H.; Dolken, G.; Stilgenbauer, S.; Panse, J.; Balabanov, S.; Hau, P.; Frickhofen, N.; Bentz, M.; Röth, Alexander; Mohle, R.; Birnbaum, T.; Pfreundschuh, M.; Hader, C.; Ihorst, G.; Deckert, M.; Prinz, M.; Schorb, E.; Fricker, H.; Kasenda, B.; Finke, J.
    Sequential High Dose Immuno-Chemotherapy Followed by Autologous Peripheral Blood Stem Cell Transplantation for Patients with Untreated Primary Central Nervous System Lymphoma - a Multicentre Study by the Collaborative PCNSL Study Group Freiburg
    In: Blood, Jg. 120, 2012, Nr. 21, -
  • Sellmann, Ludger; Scholtysik, R.; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Röth, Alexander
    Significance of chromosomal aberrations and HMGA2 expression in Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Onkologie, Jg. 35, 2012, Nr. Suppl. 6, S. 220 – 221
  • Hanoun, Maher; Röth, Alexander; Dührsen, Ulrich; Brock, Franz-Eduard
    Acral ischemia as a presenting manifestation of essential thrombocythemia
    In: International Journal of Hematology, Jg. 94, 2011, Nr. 3, S. 219 – 220
    DOI
  • Röth, Alexander; Dührsen, Ulrich; Christoph, Sandra; Hock, Christina; Konik, Anna
    Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab : safety, efficacy, and unexpected laboratory phenomena
    In: International Journal of Hematology, Jg. 93, 2011, Nr. 6, S. 704 – 714
    DOI
  • Schrezenmeier, Hubert; Bettelheim, Peter; Panse, Jens; Schubert, Joerg; Hochsmann, Britta; Röth, Alexander; Nebe, Thomas
    Empfehlungen zur Diagnostik der Paroxysmalen nächtlichen Hämoglobinurie : deutsch – österreichischer Konsensus
    In: Laboratoriumsmedizin, Jg. 35, 2011, Nr. 6, S. 315 – 327
    DOI
  • Korfel, A.; Fischer, L.; Martus, P.; Moehle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Mergenthaler, H.; Hundsberger, T.; Leithäuser, M.; Birnbaum, T.; Florschütz, A.; Jahnke, Klaus; Herrlinger, U.; Weller, M.; Thiel, E.
    Impact of meningeal dissemination (MD) on outcome in primary CNS lymphoma in the G-PCNSL-SG1 trial
    In: Journal of Clinical Oncology (JCO), Jg. 29, 2011, Nr. 15_suppl, S. 2026
    DOI
  • Martus, P.; Jahnke, Klaus; Korfel, A.; Rose, T.; Fischer, L.; Moehle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H.; Leithäuser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Birkmann, J.; Weller, M.; Thiel, E.
    Prognostic factors for chemotherapy-related toxicity in primary central nervous system lymphoma (PCNSL) treated with high-dose methotrexate (HDMTX) with or without ifosfamide: Results from a German phase III trial (G-PCNSL-SG-1)
    In: Journal of Clinical Oncology (JCO), Jg. 29, 2011, Nr. 15_suppl, S. 2005
    DOI
  • Jahnke, Klaus; Korfel, A.; Martus, P.; Lokka, S.; Moehle, R.; Griesinger, F.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H.; Leithäuser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Florschütz, A.; Fischer, L.; Weller, M.; Thiel, E.
    Prognostic factors for response and survival in primary central nervous system lymphoma (PCNSL) from a randomized phase III trial (G-PCNSL-SG-1)
    In: Journal of Clinical Oncology (JCO), Jg. 29, 2011, Nr. 15_suppl, S. 2004
    DOI
  • Sellmann, Ludger; Röth, Alexander; Baerlocher, Gabriela M.; Küppers, Ralf; Siemer, Dörte; Seifert, Marc; Dürig, Jan; Dührsen, Ulrich; Nückel, Holger; Opalka, Bertram; Bartels, Marius; de Beer, Dirk
    Telomeres and prognosis in patients with chronic lymphocytic leukaemia
    In: International Journal of Hematology, Jg. 93, 2011, Nr. 1, S. 74 – 82
    DOI
  • Röth, Alexander; Dührsen, Ulrich
    Treatment of paroxysmal nocturnal hemoglobinuria in the era of eculizumab
    In: European Journal of Haematology, Jg. 87, 2011, Nr. 6, S. 473 – 479
    DOI
  • Hanoun, Maher; Schmitz, Klaus Jürgen; Dührsen, Ulrich; Röth, Alexander
    Amyloid tumour
    In: British Journal of Haematology, Jg. 150, 2010, Nr. 4, S. 387
    DOI
  • Röth, Alexander; Dührsen, Ulrich
    Cold agglutinine disease
    In: European Journal of Haematology, Jg. 84, 2010, Nr. 1, S. 91
    DOI
  • Thiel, Eckhard; Korfel, Agnieszka; Martus, Peter; Kanz, Lothar; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; von Toll, Theda; Hundsberger, Thomas; Mergenthaler, Hans-Günther; Leithäuser, Malte; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Plasswilm, Ludwig; Nägele, Thomas; Pietsch, Torsten; Bamberg, Michael; Weller, Michael
    High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1) : a phase 3, randomised, non-inferiority trial
    In: The Lancet Oncology, Jg. 11, 2010, Nr. 11, S. 1036 – 1047
    DOI
  • Röth, Alexander; Hüttmann, Andreas; Dührsen, U.; Philipp, Thomas
    Inhibition of the Terminal Complement System Using Eculizumab for the Treatment of Cold Agglutinin Disease (CAD)
    184. Tagung der Rheinisch-Westfälischen Gesellschaft für Innere Medizin e.V.,
    In: Medizinische Klinik, Jg. 105, 2010, Nr. 3, S. 213 – 214
    DOI
  • Christoph, S.; Sellmann, Ludger; Röth, Alexander; Elmaagacli, Ahmet Hayri; Beelen, Dietrich; Dührsen, Ulrich
    Intraperitoneal and intrapleural application of Rituximab in refractory CD20-positive B-cell lymphoma
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie, Jg. 33, 2010, Nr. Suppl. 6, S. 253
    DOI
  • Konik, A.; Dührsen, Ulrich; Röth, Alexander
    Longitudinal analysis of the monospecific coombs test in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) chronically treated with Eculizumab
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie, Jg. 33, 2010, Nr. Suppl. 6, S. 50
    DOI
  • Konik, Anna; Dührsen, Ulrich; Röth, Alexander
    Nodular lesions of the scalp and a mediastinal mass in T cell acute lymphoblastic leukemia
    In: International Journal of Hematology, Jg. 92, 2010, Nr. 1, S. 3 – 4
    DOI
  • Röth, Alexander; Peine, Sven; Dührsen, Ulrich
    Paroxysmal nocturnal hemoglobinuria turning Coombs-positive
    In: International Journal of Hematology, Jg. 91, 2010, Nr. 2, S. 159 – 160
    DOI
  • Christoph, Sandra; Hüttmann, Andreas; Dührsen, Ulrich; Röth, Alexander
    Porphyria cutanea tarda
    In: British Journal of Haematology, Jg. 148, 2010, Nr. 4, S. 493
    DOI
  • Röth, Alexander; Schubert, J.; Schrezenmeier, Hubert; Dührsen, Ulrich
    Paroxysmale nächtliche Hämoglobinurie (PNH) : Pathogenese, Diagnostik und Therapie
    In: Deutsche Medizinische Wochenschrift - DMW, Jg. 134, 2009, Nr. 9, S. 404 – 409
    DOI, Online Volltext (Open Access)
  • Röth, Alexander; Baerlocher, Gabriela M.
    Telomere Biology in T Cells : An Important Brake on the Road of Their Life Span?
    In: Clinical leukemia, Jg. 3, 2009, Nr. 1, S. 41 – 46
    DOI
  • Röth, Alexander; Baerlocher, Gabriela M.
    Dyskeratosis congenita
    In: British Journal of Haematology, Jg. 141, 2008, Nr. 4, S. 412
    DOI
  • Röth, Alexander; Dührsen, Ulrich
    Paroxysmale nächtliche Hämoglobinurie (PNH) : Aktuelle Diagnostik und Therapieansätze
    In: Arzneimitteltherapie (AMT), 2008, Nr. 3, S. 96 – 101
  • Röth, Alexander; de Beer, Dirk; Nückel, Holger; Sellmann, Ludger; Dührsen, Ulrich; Baerlocher, Gabriele M.
    Significantly shorter telomeres in T-cells of patients with ZAP-70+/CD38+ chronic lymphocytic leukaemia
    In: British Journal of Haematology, Jg. 143, 2008, Nr. 3, S. 383 – 386
    DOI
  • Röth, Alexander; Dührsen, Ulrich; Baerlocher, Gabriele M.; Himmelreich, H.; Schneider, L.
    Impact of culture conditions on the proliferative lifespan of human T cells in vitro
    In: Cytotherapy : official journal of ISCT, the International Society for Cellular Therapy, Jg. 9, 2007, Nr. 1, S. 91 – 98
    DOI
  • Röth, Alexander; Dürig, Jan; Himmelreich, H.; Bug, S.; Siebert, Reiner; Dührsen, Ulrich; Lansdorp, M.; Baerlocher, Gabriele
    Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia
    In: Leukemia, Jg. 21, 2007, Nr. 12, S. 2456 – 2462
    DOI
  • Hillmen, Peter; Luzzatto, Lucio; Rother, Russel P.; Mojcik, Christopher F.; Rollins, Scott A.; Maciejewski, Jaroslaw; Fu, Chieh-Lin; Schrezenmeier, Hubert; Hill, Anita; Risitano, Antonio M.; Browne, Paul; Nakamura, Ryotaro; Elebute, Modupe O.; Szer, Jeffrey; Röth, Alexander; Muus, Petra; Socié, Gerard; Brodsky, Robert A.; Schubert, Jörg; Young, Neal S.
    The complement inhibitor Eculizumab in paroxysmal nocturnal hemoglobinuria
    In: The New England Journal of Medicine, Jg. 355, 2006, Nr. 12, S. 1233 – 1243
    DOI
  • Röth, Alexander; Lansdorp, Peter M.; Dührsen, Ulrich; Chavez, Elisabeth; Schertzer, Mike; Baerlocher, Gabriele M.
    Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT
    In: Blood, Jg. 106, 2005, Nr. 1, S. 43 – 50
    DOI
  • Röth, Alexander; Sutherland, H.J.; Lansdorp, P.M.; Vercauteren, S.
    Telomerase is limiting the growth of acute myeloid leukemia cells
    In: Leukemia, Jg. 17, 2003, Nr. 12, S. 2410 – 2417
    DOI
  • Röth, Alexander; Luiten, Rosalie M.; Spits, Hergen; Lansdorp, Peter M.; Schertzer, Mike; Chavez, Elizabeth A.; Pène, Jerome; Yssel, Hans
    Telomerase levels control the lifespan of human T lymphocytes
    In: Blood, Jg. 102, 2003, Nr. 3, S. 849 – 857
    DOI

    • Abstracts

  • Kelly, Richard; He, Guangsheng; Brodsky, Andres; Röth, Alexander; Han, Bing
    COMMODORE 2 : Crovalimab 2-year efficacy and safety in complement inhibitor-naïve patients with paroxysmal nocturnal haemoglobinuria
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 206, 2025, Nr. S1: 65th Annual Scientific Meeting of the British Society for Haematology; 27-29 April 2025; Glasgow, BSH25-PO131
    DOI (Open Access)
  • Kulasekararaj, Austin; Peffault de Latour, Regis; Röth, Alexander; Risitano, Antonio M.
    Iptacopan demonstrates long-term efficacy and safety in patients with paroxysmal nocturnal haemoglobinuria (PNH) : APPLY_PNH
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 206, 2025, Nr. S1: 65th Annual Scientific Meeting of the British Society for Haematology; 27-29 April 2025; Glasgow, BSH25-PO132
    DOI (Open Access)
  • Kulasekararaj, Austin; Han, Bing; Ueda, Yasutaka; Röth, Alexander; Risitano, Antonio
    Iptacopan maintains efficacy and safety in complement inhibitor-naive patients with paroxysmal nocturnal haemoglobinuria (PNH) : APPOINT-PNH
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 206, 2025, Nr. S1: 65th Annual Scientific Meeting of the British Society for Haematology; 27-29 April 2025; Glasgow, BSH25-OR29
    DOI (Open Access)
  • Broome, Catherine M.; Michel, Marc; Barcellini, Wilma; Jaeger, Ulrich; Ueda, Yasutaka; Hill, Quentin A.; Cid, Joan; Wu, Jiangming; Srivastava, Shruti; Wardęcki, Marek; Patel, Reena; Yoo, Ronnie; Röth, Alexander
    First Interim Analysis of Patients with Cold Agglutinin Disease (CAD) Patients and the Sutimlimab-Treated Subgroup from the Cadence Registry
    The 66th ASH Annual Meeting, December 7-10, 2024, San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 7667
    DOI (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Ademokun, Christine; Chitnis, Shripad; Matviykiv, Sofiya; Vitaliti, Alessandra; Chen, Chi; Katsanou, Vasiliki; Chawla, Raghav; Al-Samkari, Hanny
    Iptacopan Monotherapy in Patients with Cold Agglutinin Disease : Phase II Study Results
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 2457
    DOI (Open Access)
  • Kulasekararaj, Austin G.; Czyz, Jaroslaw; Flynn, Catherine; Gastal, Gabriela Roncone; Hus, Marek; Lalayanni, Chrysavgi; Nur, Erfan; Scheinberg, Phillip; Ueda, Yasutaka; Vannucchi, Alessandro Maria; Vidriales Vicente, Maria; Viigimaa, Iige; Buatois, Simon; Chang, Alice C.; Chebon, Sammy; Röth, Alexander
    Phase III COMMODORE 2 and 1 Trials : Characterization of Breakthrough Hemolysis Events in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab or Eculizumab
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 1323 – 1325
    DOI (Open Access)
  • Röth, Alexander; He, Guangsheng; Brodsky, Andres; Chai-Adisaksopha, Chatree; Comia, Narcisa Sonia; Gaya, Anna; Höglund, Martin; Kelly, Richard J.; Kori, Ahlam Naila; Lee, Je-Hwan; Obara, Naoshi; Risitano, Antonio M; Appius, Anita; Beveridge, Leigh; Gentile, Brittany; Zhang, Zilu; Han, Bing; Sreckovic, Sasha
    Phase III Randomized COMMODORE 2 Trial : 2-Year Efficacy and Safety of Crovalimab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Naive to Complement Inhibition
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 2687 – 2687
    DOI (Open Access)
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Wang, Jennifer; Vagge, Deepthi S.; Wardęcki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.
    26 Sustained complement C1s inhibition with sutimlimab in patients with cold agglutinin disease results in continued efficacy during part B of the randomized placebo-controlled phase 3 CADENZA study (NCT03347422)
    In: Immunobiology. Amsterdam: Elsevier, Jg. 228, 2023, Nr. 5, 152483
    DOI
  • Lundberg, Pontus; de la Iglesia, Silvia; Kelly, Richard J; Kulasekararaj, Austin; Nishimura, Jun-Ichi; Risitano, Antonio M; Röth, Alexander; Buatois, Simon; Chebon, Sammy; Patel, Himika; Kiialainen, Anna
    Biomarker Analyses in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Eculizumab : Results from the Phase III Randomized COMMODORE 2 Trial
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 4088 – 4088
    DOI (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Jaeger, Ulrich; Ueda, Yasutaka; Michel, Marc; Hill, Quentin A.; Srivastava, Shruti; Yoo, Ronnie; Broome, Catherine M.
    Cold Agglutinin Disease (CAD) Real-World Evidence (CADENCE) Registry : Update to the Study Design of the First International, Prospective CAD Registry
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 7341 – 7342
    DOI (Open Access)
  • Broome, Catherine M.; Barcellini, Wilma; Ueda, Yasutaka; Khan, Umer; Patel, Reena; Wardęcki, Marek; Kralova, Katarina; Srivastava, Shruti; Röth, Alexander
    Combined Safety Data for Sutimlimab in Cold Agglutinin Disease: : A Post-Hoc Analysis of the Phase 3 Cardinal and Cadenza Studies
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 3833 – 3833
    DOI (Open Access)
  • Röth, Alexander; Peffault de Latour, R.; Kulasekararaj, A.; Risitano, A. M.; et al.
    Efficacy and safety of oral therapy with iptacopan compared to standard intravenous therapy with eculizumab or ravulizumab in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) : results of the randomized controlled open-label multicenter phase III study APPLY-PNH
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 42 – 44
    DOI (Open Access)
  • Röth, Alexander; Weitz, Ilene; Ueda, Yasutaka; Bozzi, Sylvie; Patel, Reena; Karaouni, Alia; Yoo, Ronnie; Cella, David; Wang, Jennifer
    Efficacy of Sutimlimab in Improving FACIT-Fatigue Scores in Patients with Cold Agglutinin Disease : A Post-Hoc Analysis of the Phase 3 Cadenza (Part A) Study
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 5558 – 5560
    DOI (Open Access)
  • Risitano, Antonio M; Kulasekararaj, Austin; Röth, Alexander; Scheinberg, Phillip; Ueda, Yasutaka; de Castro, Carlos; Di Bona, Eros; Griffin, Morag; Langemeijer, Saskia MC; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor AQ; Panse, Jens; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Gaya, Anna; Huang, Wei-Han; Kitawaki, Toshio; Kutlar, Abdullah; Maciejewski, Jaroslaw P.; Notaro, Rosario; Pullarkat, Vinod; Schubert, Jörg; Terriou, Louis; Uchiyama, Michihiro; Sicre De Fontbrune, Flore; Frieri, Camilla; Alashkar, Ferras; Gandhi, Shreyans; Kumar, Rakesh; Thorburn, Christine; Maitra, Samopriyo; Solar-Yohay, Susan; Lawniczek, Tomasz; Dahlke, Marion; Peffault De Latour, Régis
    Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia : Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial
    65th Annual Meeting of the American-Society-of-Hematology (ASH); DEC 09-12, 2023; San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 571 – 571
    DOI (Open Access)
  • Röth, Alexander; Risitano, A. M.; Han, B.; Peffault de Latour, R.; et al.
    Oral therapy with the complement factor B inhibitor iptacopan increases hemoglobin concentration and relieves fatigue symptoms in complement inhibitor-naive adults with paroxysmal nocturnal hemoglobinuria : Results of the single-arm, open-label, multicenter phase III APPOINT-PNH study
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 45
    DOI (Open Access)
  • Kulasekararaj, Austin; Gonzalez Fernandez, Fernando Ataulfo; Scheinberg, Phillip; Straetmans, Nicole; Ueda, Yasutaka; Gentile, Brittany; Stefani, Jennifer; Uguen, Marianne; Röth, Alexander
    Patient Preferences and Treatment Satisfaction in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Approved C5 Inhibitors in the Phase III Randomized COMMODORE 1 and COMMODORE 2 Trials
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 5628 – 5630
    DOI (Open Access)
  • Röth, Alexander; Patriquin, Christopher J.; Szer, Jeff; Terriou, Louis; Patel, Ami; Gustovic, Philippe; Nishimura, Jun-Ichi; Brodsky, Robert A.
    Ravulizumab Effectiveness in the Real World : Evidence from the International PNH Registry
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 2722 – 2722
    DOI (Open Access)
  • Majerus, Elaine M; Mulherin, Brian; Wilson, Koo; Fishman, Jesse; Mellor, Jennifer; Earl, Lucy; Röth, Alexander
    Real-World Treatment Outcomes of Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated with Pegcetacoplan and Complement Protein 5 Inhibitors (C5i)
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 5633 – 5634
    DOI (Open Access)
  • Röth, Alexander; FU, Rong; He, Guangsheng; Alzahrani, Hazza A; Chou, Sheng-Chieh; Hicheri, Yosr; Kazmierczak, Maciej; Lacorte Recova, Viviane; Uchiyama, Michihiro; Vladareanu, ANA Maria; Beveridge, Leigh; Buatois, Simon; Buri, Muriel; Shi, Dayu; Balachandran, Nadiesh; Srekovic, Sasha; Scheinberg, Phillip
    Safety of Crovalimab Versus Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) : Pooled Results from the Phase III COMMODORE 1, COMMODORE 2, and COMMODORE 3 Studies
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 575 – 577
    DOI (Open Access)
  • Röth, Alexander; Berentsen, S.; Barcellini, W.; Broome, C. M.; et al.
    Sustained complement C1s inhibition with sutimlimab in patients with cold agglutinin disease results in continued efficacy during part B of the randomized placebo-controlled phase 3 CADENZA study (NCT03347422)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 120
    DOI (Open Access)
  • Schorb, E.; Isbell, L.; Kerkhoff, A.; Röth, Alexander; Illerhaus, G.; et al.; Kooperative Studiengruppe ZNS-Lymphome
    Altersadaptierte Hochdosistherapie und autologe Stammzelltransplantation bei älteren Patienten mit Erstdiagnose eines primären ZNS-Lymphoms : die Phase II MARTA Studie
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 59
    DOI (Open Access)
  • Röth, Alexander; Alashkar, Ferras; Panse, J.; Sockel, K.; Haferlach, T.; Hübel, K.; Blau, I. W.; Platzbecker, U.; Höchsmann, B.; Schrezenmeier, H.
    Ausgangscharakteristika von Patienten mit Paroxysmaler Nächtlicher Hämoglobinurie (PNH) : Daten aus dem Deutschen PNH-Register einschließlich Eculizumab, Ravulizumab und unbehandelten Patienten
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 174
    DOI (Open Access)
  • Fattizzo, Bruno; Röth, Alexander; Broome, Catherine M.; Khan, Umer; Shafer, Frank; Cordoba, Matias; Barcellini, Wilma
    Concomitant Use of Sutimlimab and COVID-19 Vaccines in Patients with Cold Agglutinin Disease from the Phase 3 Cardinal and Cadenza Studies
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Suppl. 1, S. 2839 – 2841
    DOI (Open Access)
  • Illerhaus, Gerald; Ferreri, Andrés J.M.; Binder, Mascha; Borchmann, Peter; Hasenkamp, Justin; Stilgenbauer, Stephan; Roeth, Alexander; Weber, Thomas; Egerer, Gerlinde; Ernst, Thomas; Hertenstein, Bernd; Lenz, Georg; Kobbe, Guido; Brunnberg, Uta; Schmidt, Christian; Kneba, Michael; Dreyling, Martin; Möhle, Robert; Panse, Jens; Heinicke, Thomas; Schroll, Sebastian; Larsen, Thomas S.; Salwender, Hans; Naumann, Ralph; Hess, Georg; Thurner, Lorenz; Pukrop, Tobias; Keller, Ulrich; Blystadt, Anne Kirsti; Kroschinsky, Frank P.; Re, Francesca; Pulczynski, Elisa; Orsucci, Lorella; Pospiech, Lisa; Deckert, Martina; Ponzoni, Maurilio; Wendler, Julia; Valk, Elke; Calimeri, Teresa; Kasenda, Benjamin; Trepel, Martin; Fricker, Heidi; von Gottberg, Philipp; Burger, Elvira; Ihorst, Gabriele; Grishina, Olga; Hader, Claudia; Zucca, Emanuele; Finke, Jürgen; Schorb, Elisabeth
    Effects on Survival of Non-Myeloablative Chemoimmunotherapy Compared to High-Dose Chemotherapy followed by Autologous Stem Cell Transplantation (HDC-ASCT) as Consolidation Therapy in Patients with Primary CNS Lymphoma : Results of an International Randomized Phase III Trial (MATRix/IELSG43)
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 2, S. 10 – 13
    DOI, Online Volltext (Open Access)
  • Röth, Alexander; Peffault de Latour, R.; Soret, J.; Frieri, C.; Sicre de Fontbrune, F.; Marano, L.; Alashkar, Ferras; Benajiba, L.; Marotta, S.; Kulmatycki, K.; Nidamarthy, P. K.; Fagan, N.; Junge, G.; Risitano, A. M.
    Einsatz des oralen Komplementfaktor B-Inhibitors Iptacopan bei Patienten (pts) mit Paroxysmaler Nächtlicher Hämoglobinurie (PNH) mit anhaltende Hämolyse trotz einer Anti-C5 Therapie : langfristige Wirksamkeit und Sicherheit nach dem Absetzen von Eculizumab (ECU)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 173 – 174
    DOI (Open Access)
  • Röth, Alexander; Berentsen, S.; Barcellini, W.; D‘Sa, S.; Jilma, B.; Michel, M.; Weitz, I. C.; Yamaguchi, M.; Nishimura, J.-i.; Vos, J. M.; Storek, M.; Wong, N. W.; Patel, P.; Jiang, X.; Vagge, D.; Wardęcki, M.; Shafer, F.; Lee, M.; Broome, C. M.
    Hemmung von Komplement C1s durch Sutimlimab (SUT) bei Patienten mit Cold Agglutinin Disease (CAD) : Ergebnisse zur Wirksamkeit und Sicherheit aus der randomisierten, placebokontrollierten Phase-3 CADENZA-Studie (NCT03347422)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 172 – 173
    DOI (Open Access)
  • Broome, Catherine M.; Barcellini, Wilma; Röth, Alexander; Karaouni, Alia; Joly, Florence; Yoo, Ronnie; Terlinden, Augustin; Adeyemi, Ayo; Moride, Yola; Hill, Quentin A.
    Hemolytic Markers, Mortality, and Thromboembolic Events in Cold Agglutinin Disease (CAD) : A Retrospective Analysis of the Optum Electronic Health Record Database in the United States
    64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH): DEC 10-13, 2022; New Orleans, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1, S. 5306 – 5308
    DOI (Open Access)
  • Schorb, Elisabeth; Isbell, Lisa; Kerkhoff, Andrea; Mathas, Stephan; Braulke, Friederike; Egerer, Gerlinde; Roeth, Alexander; Schliffke, Simon Christian; Borchmann, Peter; Brunnberg, Uta; Kroschinsky, Frank P.; Möhle, Robert; Rank, Andreas; Wellnitz, Dominique; Kasenda, Benjamin; Pospiech, Lisa; Wendler, Julia; Ihorst, Gabriele; Scherer, Florian; Deckert, Martina; Henkes, Elina; Duyster, Justus; Finke, Jürgen; Illerhaus, Gerald
    High-Dose Chemotherapy and Autologous Stem Cell Transplant in Elderly and Fit Primary CNS Lymphoma Patients : a Multicenter Study By the Cooperative PCNSL Study Group (MARTA study)
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1, S. 1773 – 1774
    DOI (Open Access)
  • Alashkar, Ferras; Lange, C. P.; Yamamoto, R.; Reinhardt, H. Christian; Röth, Alexander
    Luspatercept bei Patienten mit transfusionsabhängiger β-Thalassämie : die erste reale Analyse
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 49
    DOI (Open Access)
  • Peffault de Latour, Regis; Roeth, Alexander; Kulasekararaj, Austin; Scheinberg, Phillip; Ueda, Yasutaka; de Castro, Carlos M; Di Bona, Eros; Schrezenmeier, Hubert; Langemeijer, Saskia MC; Barcellini, Wilma; Tavitian, Suzanne; Panse, Jens; Schafhausen, Philippe; Mauad, Vitor AQ; Kerloeguen, Cecile; Levitch, Rafael; Kumar, Rakesh; Thorburn, Christine; Maitra, Samopriyo; Dahlke, Marion; Risitano, Antonio M
    Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia : Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 2, S. 5 – 9
    DOI, Online Volltext (Open Access)
  • Roeth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Tvedt, Tor Henrik Anderson; Yamaguchi, Masaki; Murakhovskaya, Irina; Lee, Michelle; Shafer, Frank; Wardecki, Marek; Wang, Jennifer; Yoo, Ronnie; Mshijid, Jerome; Weitz, Ilene C.
    Sutimlimab Provides Sustained Improvements in Patient-Reported Outcomes and Quality of Life in Patients with Cold Agglutinin Disease : Open-Label Extension of the Randomized, Phase 3 Cadenza Study
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1, S. 70 – 72
    DOI (Open Access)
  • Jilma, Bernd; Roman, Eloy; Ueda, Yasutaka; Mappa, Silvia; Szamosi, Johan; Savage, Jessica; Röth, Alexander
    Trial in Progress : Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients with Cold Agglutinin Disease (CASCADE)
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Suppl. 1, S. 5326 – 5327
    DOI (Open Access)
  • Alashkar, Ferras; Röth, Alexander; Reinhardt, H. Christian; Franzen, C.; Peetz, J.; Papathanasiou, Maria; Reinhardt, Dirk; Halimeh, S.; Aramayo-Singelmann, C.
    Voxelotor bei Jugendlichen und Erwachsenen mit Sichelzellkrankheit : erste Erfahrungen aus dem deutschen Härtefallprogramm
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 48
    DOI (Open Access)
  • Röth, Alexander; Berentsen, S.; Barcellini, W.; D’Sa, S.; Jilma, B.; Michel, M.; Weitz, I.C.; Yamaguchi, M.; Nishimura, J.-I.; Jos, J. M. I.; Patel, P.; Schaible, B.; Jiang, X.; Vagge, D. S.; Wardęcki, M.; Shafer, F.; Lee, M.; Broome, C. M.
    C1s-targeted inhibition of classical complement pathway by sutimlimab in cold agglutinin disease (CAD) : Efficacy and safety results from the randomized, placebo (PBO)-controlled phase 3 CADENZA study
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 44, 2021, Nr. Supplement 2, S. 40 – 41
    DOI (Open Access)
  • Beier, Fabian; Tometten, Mareike; Kirschner, Martin; Halfmeyer, Insa; Vieri, Margherita; Kricheldorf, Kim; Maurer, Angela; Röth, Alexander; Platzbecker, Uwe; Radsak, Markus P.; Schafhausen, Philippe; Corbacioglu, Selim; Hoechsmann, Britta; Wilk, C. Matthias; Hinze, Claas; Chromik, Jörg; Egle, Alexander; Heuser, Michael; Kreuter, Michael; Kurth, Ingo; Koschmieder, Steffen; Panse, Jens; Meyer, Robert; Isfort, Susanne; Brummendorf, Tim H
    Clinical Presentation of Patients with Adult Late-Onset Telomere Biology Disorders : Results from the Aachen Telomeropathy Registry
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 1130 – 1132
    DOI (Open Access)
  • Röth, Alexander; Hoechsmann, Britta; Griffin, Morag; De Castro, Carlos M.; Szer, Jeffrey; Usuki, Kensuke; Soret, Juliette; Hamdani, Mohamed; Ajayi, Temitayo; Sarda, Sujata P.; Panse, Jens
    Effect of Pegcetacoplan on Quality of Life in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Pegasus Phase 3 Trial Comparing Pegcetacoplan to Eculizumab
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 193, 2021, Nr. S1, S. 198 – 199
    DOI (Open Access)
  • Panse, J.; Höchsmann, B.; Griffin, M.; De Castro, C. M.; Szer, J.; Usuki, K.; Soret, J.; Al-Adhami, M.; Chen, C.; Sarda, S. P.; Röth, Alexander
    Effect of Pegcetacoplan on quality of life in patients with Paroxysmal Nocturnal Hemoglobinuria : Week 48 of PEGASUS phase 3 trial comparing Pegcetacoplan to Eculizumab
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 44, 2021, Nr. Supplement 2, S. 41 – 42
    DOI (Open Access)
  • Röth, Alexander
    Efficacy and Safety at 48 Weeks of Pegcetacoplan in Adult Paroxysmal Nocturnal Hemoglobinuria Patients with Suboptimal Response to Prior Eculizumab Treatment
    Society of Hematologic Oncology 9th Annual Meeting ; September 8–11, 2021, Houston, Texas, USA & Virtual Venue,
    In: Clinical Lymphoma, Myeloma & Leukemia. ‎New York: Elsevier, Jg. 21, 2021, Nr. Suppl. 1, S. S341 – S342
    DOI
  • Röth, Alexander; Lenderking, William R.; Sarda, Sujata P.; Baver, Scott B.; Hamdani, Mohamed; Hsieh, Ray; Shaffer, Shannon; Yeh, Michael; Cella, David
    Improvements in Fatigue And Physical Function Evaluated Through Changes in Clinical Outcomes In Paroxysmal Nocturnal Hemoglobinuria : Post-HOC Analyses From The Pegasus Study
    In: Bone Marrow Transplantation. London: Springer Nature, Jg. 56, 2021, Nr. Suppl. 1, S. 149 – 150
  • Röth, Alexander; Lenderking, William R; Sarda, Sujata P.; Baver, Scott B.; Hamdani, Mohamed; Hsieh, Ray; Shaffer, Shannon; Yeh, Michael; Cella, David
    Improvements in Fatigue and Physical Function Evaluated Through Changes in Clinical Outcomes in Paroxysmal Nocturnal Hemoglobinuria : Post-Hoc Analyses from the PEGASUS Study
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 193, 2021, Nr. S1, S. 195
    DOI
  • Barcellinia, W.; Röth, Alexander; D'Sa, S.; Berentsen, S.; et al.
    Inhibition of Complement C1S with Sutimlimab in Patients with Cold Agglutinin Disease (CAD) : Interim Results of the Phase 3 Cardinal Study Long-Term Follow-up
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal. Pavia; Messina; Rom: Ferrata Storti Foundation, Jg. 106, 2021, Nr. S3: Abstract Book, 48th Congress of the Italian Society of Hematology, 24-27 October 2021, S. 107
    DOI (Open Access)
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-Ichi; Vos, Josephine M.I.; Storek, Michael; Wong, Nancy; Patel, Parija; Schaible, Braydon; Jiang, Xiaoyu; Vagge, Deepthi; Wardecki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.
    Inhibition of Complement C1s By Sutimlimab in Patients with Cold Agglutinin Disease (CAD) : Efficacy and Safety Results from the Randomized, Placebo-Controlled Phase 3 CADENZA Study
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 349 – 351
    DOI (Open Access)
  • Calimeri, T.; Cwynarski, K.; Pulczynski, E.; Röth, Alexander; Ferreri, A. J. M.; et al.
    Results of the IELSG32 Trial at a Median Follow-Up of 88 Months Demonstrate that Matrix Followed by Autologous Transplant is Associated with Excellent Survival and Neurotolerabilty in Patients with Primary CNS Lymphoma
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal. Pavia; Messina; Rom: Ferrata Storti Foundation, Jg. 106, 2021, Nr. 10, S3: 48th Congress of the Italian Society of Hematology, 24-27 October 2021, S. 33
    DOI (Open Access)
  • Griffin, Morag; Hillmen, Peter; Szer, Jeffrey; Weitz, Ilene C.; Röth, Alexander; Hoechsmann, Britta; Panse, Jens; Usuki, Kensuke; Kiladjian, Jean-Jacques; De Castro, Carlos M.; Nishimori, Hisakazu; Tan, Lisa; Hamdani, Mohamed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio; De Latour, Regis Peffault
    Results of the Pegasus Phase 3 Randomized Trial Demonstrating Superiority of the C3 Inhibitor, Pegcetacoplan, Compared to Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 193, 2021, Nr. S1
    DOI (Open Access)
  • Hoechsmann, B.; Hill, A.; de Latour, R. Peffault; Röth, Alexander; Devos, T.; Patriquin, C.; Chou, W. C.; Jain, D.; Zu, K.; Lee, J. W.
    Risk Factors for Thrombotic Events in Patients with PNH : A Nested Case-Control Study in the International PNH Registry
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 193, 2021, Nr. S1, S. 193 – 194
    DOI
  • Barcellini, Wilma; Röth, Alexander; Anderson Tvedt, T. H.; Weitz, I. C.; et al.
    Sutimlimab, a Complement C1S Inhibitor, Improves Quality of Life in Patients with Cold Agglutinin Disease : Patient-Reported Outcomes Results of the Phase 3 Cardinal Study
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal. Pavia; Messina; Rom: Ferrata Storti Foundation, Jg. 106, 2021, Nr. S3: 48th Congress of the Italian Society of Hematology, 24-27 October 2021, Abstract Book, S. 111 – 112
    DOI (Open Access)
  • Risitano, A.M.; Röth, Alexander; Soret, J.; Frieri, C.; Sicre de Fontbrune, F.; Marano, L.; Alashkar, Ferras; Benajiba, L.; Marotta, S.; Rozenberg, I.; Milojevic, J.; End, P.; Nidamarthy, P.K.; Junge, G.; Peffault de Latour, R.
    The Oral Complement Factor B Inhibitor Iptacopan is Safe and Effective in Improving Hematological Response in Paroxysmal Nocturnal Hemoglobinuria Patients with Poor Response to Eculizumab, even in Monotherapy
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal. Pavia; Messina; Rom: Ferrata Storti Foundation, Jg. 106, 2021, Nr. 10, S3: 48th Congress of the Italian Society of Hematology, 24-27 October 2021, S. 106 – 107
    DOI (Open Access)
  • Ferreri, Andrés J M; Cwynarski, Kate; Pulczynski, Elisa; Fox, Christopher P.; La Rosée, Paul; Schorb, Elisabeth; Krampera, Mauro; Ilariucci, Fiorella; Orsucci, Lorella; Fabbri, Alberto; Tucci, Alessandra; Röth, Alexander; Linton, Kim; Binder, Mascha; Hemmaway, Claire; Cabras, Maria Giuseppina; Pinto, Antonio; Calimeri, Teresa; Cavalli, Franco; Zucca, Emanuele; Illerhaus, Gerald
    Treatment of Patients with Relapsed or Refractory Primary CNS Lymphoma (rrPCNSL) Enrolled in the Randomized Trials of the International Extranodal Lymphoma Study Group (IELSG)
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 1417 – 1419
    DOI (Open Access)
  • Kulasekararaj, Austin G.; Risitano, Antonio; Röth, Alexander; He, Guangsheng; Pu, Jeffrey; Wright, Lilyan; Appius, Anita; Sostelly, Alexandre; Sreckovic, Sasha; Stanzel, Sven F.; Munir, Talha; Nishimura, Jun-Ichi
    Two Currently Recruiting Randomized Phase III Trials : COMMODORE 1 and 2 Evaluating Crovalimab Vs Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria with or without Current Anti-Complement Therapy
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 138, 2021, Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 4313 – 4315
    DOI (Open Access)
  • Röth, Alexander; Jäger, U.; Jilma, B.; Barcellini, W.; Hill, A.; Hill, Q.; Kuter, D. J.; Broome, C. M.; Michel, M.; Zeerleder, S. S.; Ueda, Y.; Morales Arias, J.; Su, J.; Berentsen, S.
    Cold Agglutinin Disease (CAD) Real World Evidence (CADENCE) registry : Design of the first international, prospective CAD registry
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 180
    DOI (Open Access)
  • Sayer, Herbert Gottfried; Witzens-Harig, Mathias; Wattad, Mohammad; Korfel, Agnieszka; Hilgendorf, Inken; Franke, Georg-Nikolaus; Illerhaus, Gerald; Heinsch, Michael; Metzner, Bernd; Zinngrebe, Eva Bettina; Binder, Mascha; Ringhoffer, Mark; Röth, Alexander; Geer, Thomas; Schmidt, Volker; Dreger, Peter
    Final Results of a Prospective, Multicenter, noninterventional Study on thiotepa-based Autologous Hematopoietic Cell Transplantation (ASCT) for CNS or non-CNS Lymphoma
    46th Annual Meeting of the European Society for Blood and Marrow Transplantation ; 29 August - 1 September, 2020, Virtual Meeting,
    In: Bone Marrow Transplantation. London: Springer Nature, Jg. 55, 2020, Nr. Suppl. 1, S. 298
    DOI (Open Access)
  • Risitano, Antonio M.; Röth, Alexander; Soret, Juliette; Frieri, Camilla; Sicre de Fontbrune, Flore; Marano, Luana; Rozenberg, Izabella; Milojevic, Julie; End, Peter; Nidamarthy, Prasanna K.; Junge, Guido; Peffault de Latour, Regis
    LNP023-A New Oral Complement Factor-B Inhibitor Normalizes Hemoglobin in Paroxysmal Nocturnal Hemoglobinuria Patients with Poor Response to Eculizumab, Both as Add-on and Monotherapy
    46th Annual Meeting of the European Society for Blood and Marrow Transplantation ; 29 August - 1 September, 2020, Virtual Meeting,
    In: Bone Marrow Transplantation. London: Springer Nature, Jg. 55, 2020, Nr. Suppl. 1, S. 32 – 33
    DOI (Open Access)
  • Röth, Alexander; Barcellini, W.; D Sa, S.; Miyakawa, Y.; Broome, C. M.; Michel, M.; Kuter, D. J.; Jilma, B.; Anderson Tvedt, T. H.; Lin, S.; Jiang, X.; Reuter, C.; Hobbs, W.; Berentsen, S.
    Results from the phase 3 Cardinal study part A : Inhibition of complement C1s with Sutimlimab in patients with Cold Agglutinin Disease (CAD)
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 177
    DOI (Open Access)
  • Castro, Carlos de; Hillmen, Peter; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Hoechsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; Nishimori, Hisakazu; Tan, Lisa; Hamdani, Mohamed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio; Latour, Regis Peffault de
    Results of the PEGASUS Phase 3 Randomized Trial Demonstrating Superiority of the C3 Inhibitor, Pegcetacoplan, Compared to Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria
    SOHO 2020, 8th annual meeting of the Society of Hematologic Oncology (virtual event), 9-12 September 2020, Houston,
    In: Clinical Lymphoma, Myeloma & Leukemia. ‎New York: Elsevier, Jg. 20, 2020, Nr. Supplement 1, Proceedings of the Society of Hematologic Oncology 2020 Annual Meeting, S. S216 – S217
    DOI
  • Röth, Alexander; Hillmen, P.; Szer, J.; Weitz, I.; Höchsmann, B.; Panse, J.; Schafhausen, P.; Usuki, K.; Griffin, M.; Kiladjian, J.-J.; Castro, C. de; Nishimori, H.; Tan, L.; Hamdani, M.; Deschatelets, P.; Francois, C.; Grossi, F.; Risitano, A.; Peffault de Latour, R.
    Results of the PEGASUS phase 3 randomized trial demonstrating superiority of the C3 inhibitor, pegcetacoplan, compared to eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH)
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 176
    DOI (Open Access)
  • Röth, Alexander
    Results of the pegasus phase III trial for the comparison of pegcetacoplan with eculizumab in patients with paroxysmal nocturnal hemoglobinuria
    In: Haematologica / The Hematology Journal. Pavia; Messina; Rom: Ferrata Storti Foundation, Jg. 105, 2020, Nr. Suppl. 3, S. 110
  • Proske, P.; Aramayo-Singelmann, Carmen; Reinhardt, Dirk; Koldehoff, Michael; Reinhardt, Hans Christian; Röth, Alexander; Alashkar, Ferras
    Sickle Cell Disease (SCD) : a single-centre experience - update
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 180 – 181
    DOI (Open Access)
  • Alashkar, Ferras; Carpinteiro, Alexander; Bauer, Sebastian; Hüttmann, Andreas; Dührsen, Ulrich; Reinhardt, Hans Christian; Röth, Alexander
    Think twice : Anemia of chronic disease (ACD) due to angiomatoid fibrous histiocytoma (AFH)
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 43, 2020, Nr. Suppl. 4, S. 181
    DOI (Open Access)
  • Risitano, A.; Röth, Alexander; Hill, A.; Charbonnier, A.; Schouten, H. C.; Khaled, S.; Gutierrez, E. O.; Ogawa, M.; Yu, J.; Rottinghaus, S.; Ishiyama, K.; Kulasekararaj, A.
    A phase 3 study of Ravulizumab (ALXN1210) vs. Eculizumab in adults with paroxysmal nocturnal hemoglobinuria currently treated with Eculizumab : subgroup analysis by transfusion history and demographics
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 42, 2019, Nr. Supplement 4: Abstracts, S. 302
    DOI (Open Access)
  • Sostelly, Alexandre; Soubret, Antoine; Bucher, Christoph; Buatois, Simon; Charoin, Jean-Eric; Jordan, Gregor; Klughammer, Barbara; Dieckmann, Andreas; Fukuzawa, Taku; Gotanda, Keisuke; Shinomiya, Kenji; Yoon, Sung-Soo; Panse, Jens P.; Nishimura, Junichi; Röth, Alexander; Nagy, Zsolt; Peffault de Latour, Régis
    Characterizing C5 Inhibition with the SMART-Ig Anti-hC5 Antibody Crovalimab in PNH Patients Using Free Available Paratopes
    61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 134, 2019, Nr. Supplement_1, S. 1227 – 1227
    DOI (Open Access)
  • Alashkar, Ferras; Haverkamp, Tobias; Finckh, Ulrich; Göthert, Joachim Rudolf; Dührsen, U.; Röth, Alexander
    Clonal evolution in eltrombopag-resistant aplastic anemia indicated by a novel mutation in transcripts of the thrombopoietin-receptor MPL : a case report
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 42, 2019, Nr. Supplement 4: Abstracts, S. 147 – 148
    DOI (Open Access)
  • Sostelly, Alexandre; Buatois, Simon; Soubret, Antoine; Winter, Erica; Klughammer, Barbara; Hsu, Joy C.; Jordan, Gregor; Bucher, Christoph; Charoin, Jean-Eric; Gotanda, Keisuke; Shinomiya, Kenji; Nagy, Zsolt; Panse, Jens P.; Yoon, Sung-Soo; Peffault de Latour, Régis; Nishimura, Junichi; Röth, Alexander
    Exposure-Response Relationship of the SMART-Ig Anti-hC5 Antibody Crovalimab (SKY59): Results from the Umbrella Phase 1/2 Composer Trial in Healthy Volunteers and PNH Patients
    61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 134, 2019, Nr. Supplement_1: 61st ASH Annual Meeting, S. 3745 – 3745
    DOI (Open Access)
  • Broome, Catherine M; Röth, Alexander; Kuter, David J.; Scully, Marie; Smith, Roy; Wang, Jennifer; Reuter, Caroline; Hobbs, William
    Inhibition of the Classical Pathway of Complement with Sutimlimab in Chronic Immune Thrombocytopenic Purpura Patients without Adequate Response to Two or More Prior Therapies
    61st ASH Annual Meeting and Exposition, 07.-10.12.2019, Orlando, FL,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 134, 2019, Nr. Supplement_1, S. 898 – 898
    DOI (Open Access)
  • Kulasekararaj, Austin; Hill, Anita; Langemeijer, Saskia; Wells, Richard A.; Gonzalez-Fernandez, F. Ataulfo; Gaya, Anna; Ojeda Gutierrez, Emilio; Piatek, Caroline I.; Mitchell, Lindsay D; Usuki, Kensuke; Bosi, Alberto; Brodsky, Robert A.; Ogawa, Masayo; Yu, Ji; Ortiz, Stephan; Röth, Alexander; Lee, Jong-Wook; Peffault de Latour, Régis
    One-Year Efficacy and Safety from a Phase 3 Trial of Ravulizumab in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Receiving Prior Eculizumab Treatment
    Konferenz 61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 134, 2019, Nr. Supplement_1, S. 2231 – 2231
    DOI (Open Access)
  • Röth, Alexander; Fryzek, J.; Jiang, X.; Reichert, H.; Morales, J.; Broome, C. M.
    Seasonal patterns of anemia, hemolytic markers, healthcare resource utilization, and thromboembolic events in cold agglutinin disease
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 42, 2019, Nr. Supplement 4: Abstracts, S. 9
    DOI (Open Access)
  • Röth, Alexander; Nagy, Z.; Gaàl-Weisinger, J.; Peffault de Latour, R.; Panse, J.; Yoon, S. S.; Egyed, M.; Ichikawa, S.; Ito, Y.; Seok Kim, S.; Schrezenmeier, H.; Höchsmann, B.; Körper, S.; Sica, S.; Usuki, K.; Sostelly, A.; Higginson, J.; Dieckmann, A.; Anzures-Caberas, J.; Shinomiya, K.; Klughammer, B.; Jahreis, A.; Bucher, C.; Nishimura, J. I.
    Subcutaneous Crovalimab (SKY59) for PNH : COMPOSER long term follow-up
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 42, 2019, Nr. Supplement 4: Abstracts, S. 245
    DOI (Open Access)
  • Röth, Alexander; Risitano, A.; Jang, J. H.; Lee, G.-W.; Wanachiwanawin, W.; Schrezenmeier, H.; Yonemura, Y.; Munir, T.; Pavani, R.; Aguzzi, R.; Shafner, L.; Kulagin, A.; Sicre de Fontbrune, F.
    Transfusion requirements in adult patients with paroxysmal nocturnal hemoglobinuria naive to complement inhibitors receiving Ravulizumab or Eculizumab : results from a phase 3 non-inferiority study
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 42, 2019, Nr. Supplement 4: Abstracts, S. 97
    DOI (Open Access)
  • Struve, C.; Alashkar, Ferras; Baum, J.; Noppeney, Richard; Dührsen, U.; Röth, Alexander
    Antithymocyte Globulin (ATG), CSA and eltrombopag followed by autologous stem cell transplantation in a patient with Very Severe Aplastic Anemia (vSAA) and life-threatening pneumonia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 105
    DOI (Open Access)
  • Beier, F.; Kirschner, M.; Bouillon, A.-S.; Halfmeyer, I.; Ventura Ferreira, M.; Kricheldorf, K.; Maurer, A.; Wilop, S.; Thol, F.; Röth, Alexander; Platzbecker, U.; Radsak, M.; Ayuk, Francis A.; Corbacioglu, Selim; Höchsmann, B.; Wilk, C. M.; Hinze, C.; Chromik, J.; Egle, Alexander; Bittenbring, J. T.; Eggermann, T.; Kurth, I.; Koschmieder, S.; Schemionek, M.; Isfort, S.; Panse, J.; Brümmendorf, T. H.
    Identification of patients with classical and/or cryptic dyskeratosis congenita (DKC) by telomere length screening using different percentiles : results from the Aachen telomeropathy registry
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 126 – 127
    DOI (Open Access)
  • Alashkar, Ferras; Dampmann, M.; Herich-Terhürne, D.; Chapot, le Saout, Valerie; Dührsen, Ulrich; Rottinghaus, S. T.; Röth, Alexander
    Meningococcal-Septicemia and its resolution in a patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) receiving ALXN1210, a complement C5 inhibitor
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 198
    DOI (Open Access)
  • Röth, Alexander; Rottinghaus, S. T.; Hill, A.; Kim, J. S.; Schrezenmeier, H.; Terriou, L.; Urbano-Ispizua, A.; Wells, R. A.; Jang, J. H.; Szer, J.; Aguzzi, R.; Bachman, E. S.; Damokosh, A. I.; Shafner, L.; Lee, J.-W.
    Optimization of dose regimen for ALXN1210, a novel complement C5 inhibitor, in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) : results of 2 phase 1/2 studies
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 128
    DOI (Open Access)
  • Kulasekararaj, Austin G.; Hill, Anita; Rottinghaus, Scott T.; Langemeijer, Saskia; Wells, Richard A.; Gonzalez-Fernandez, F. Ataulfo; Gaya, Anna; Lee, Jong-Wook; Ojeda Gutierrez, Emilio; Piatek, Caroline I.; Szer, Jeffrey; Risitano, Antonio M.; Nakao, Shinji; Bachman, Eric; Shafner, Lori; Damokosh, Andrew I.; Ortiz, Stephan; Röth, Alexander; Peffault De Latour, Regis
    Results from a Phase 3, Multicenter, Non-Inferiority Study of Ravulizumab (ALXN1210) Versus Eculizumab in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Currently Treated with Eculizumab
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1, S. 625 – 625
    DOI (Open Access)
  • Cario, Holger; Schwarz, M.; Röth, Alexander; Tartaglione, I.; Gamberini, R.; Voskaridou, E.; Ricchi, Paolo; Pietrangelo, A.; Zhang, X.; Laadem, A.; Sherman, M. L.; Linde, P. G.; Piga, A.
    Results of a phase 2 study as a rationale for the BELIEVE study, a phase 3, double-blind, randomized, placebo-controlled, multicenter study to determine the efficacy and safety of luspatercept in adult patients (Pts) requiring regular RBC transfusions due to β-Thalassemia (β-Thal)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 128 – 129
    DOI (Open Access)
  • Röth, Alexander; Fryzek, Jon; Jiang, Xiaohui; Morales, Jaime; Broome, Catherine M.
    Seasonal Patterns of Anemia, Hemolytic Markers and Healthcare Resource Utilization Among Patients with Cold Agglutinin Disease in the United States : A Retrospective Analysis
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1, S. 4873 – 4873
    DOI (Open Access)
  • Alashkar, Ferras; Herich-Terhuerne, Doerte; Preising, Nicole; Duehrsen, Ulrich; Ulrich, Vogel; Röth, Alexander
    Serologic Response to Meningococcal Vaccination in Patients with Cold Agglutinin Disease (CAD) in the New Era of Complement Inhibition
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1, S. 3817 – 3817
    DOI (Open Access)
  • Drießen, M. N.; Röth, Alexander; Distelmaier, L.; Wagner, M.; Lenz, V.; Pentek, F.; Liebregts, Tobias; Dührsen, U.; Alashkar, Ferras
    Sickle Cell Disease (SCD) : A single-centre experience
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 196 – 197
    DOI (Open Access)
  • Versmold, K.; Tsagakis, Konstantinos; Alashkar, Ferras; Herich-Terhürne, D.; Dührsen, Ulrich; Röth, Alexander
    Subacute aortic dissection in a patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) on chronic treatment with eculizumab
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 199
    DOI (Open Access)
  • Röth, Alexander; Egyed, Miklos; Ichikawa, Satochi; Kim, Jin Seok; Nagy, Zsolt; Gaàl Weisinger, Julia; Panse, Jens P.; Peffault De Latour, Regis; Sicre De Fontbrune, Flore; Sica, Simona; Usuki, Kensuke; Yoon, Sung-Soo; Winter, Erica; Hsu, Joy C.; Dieckmann, Andreas; Anzures-Cabrera, Judith; Jordan, Gregor; Shinomiya, Kenji; Klughammer, Barbara; Bucher, Christoph; Jahreis, Angelika; Nishimura, Jun-Ichi
    The SMART Anti-hC5 Antibody (SKY59/RO7112689) Shows Good Safety and Efficacy in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 132, 2018, Nr. Supplement 1: 60th ASH Annual Meeting Abstracts, S. 535 – 535
    DOI (Open Access)
  • Sayer, Herbert G.; Witzens-Harig, Mathias; Wattad, Mohammed; Korfel, Agnieszka; Hilgendorf, Inken; Franke, Georg-Nikolaus; Illerhaus, Gerald; Heinsch, Michael; Metzner, Bernd; Zinngrebe, Eva Bettina; Basara, Nadezda; Binder, Mascha; Schmidt, Volker; Ringhoffer, Mark; Röth, Alexander; Geer, Thomas; Dreger, Peter
    Thiotepa-based Autologous hematopoietic stem cell transplantation (ASCT) for CNS or non-CNS lymphoma : first results of a prospective, multicenter, non-interventional study
    The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation; Mar 18 - 21, 2018; Lisboa, Portugal,
    In: Bone Marrow Transplantation. London: Springer Nature, Jg. 53, 2018, Nr. Supplement, S. 108 – 109
    Online Volltext
  • Alashkar, Ferras; Kloke, O.; Dührsen, Ulrich; Röth, Alexander
    Thrombotic storm leading to the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 199 – 200
    DOI (Open Access)
  • Alashkar, Ferras; Drießen, M. N.; Wagner, M.; Lenz, V.; Klump, Hannes; Pentek, F.; Baum, J.; Röth, Alexander; Dührsen, Ulrich; Liebregts, Tobias
    Veno-venous Extracorporal Membrane Oxygenation (VV-ECMO) in a female patient with Sickle Cell Disease (SCD) and Fulminat Acute Chest Syndrome (ACS) : A case report
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 198
    DOI (Open Access)
  • Röth, Alexander; Dirkmann, Daniel; Lenz, V.; Heinrichs, Stefan; Fuchs, Norbert; Breyer, M.; Dührsen, Ulrich; Peters, Jürgen; Horn, Peter
    Eculizumab rescue therapy in ABO-incompatible red blood cell transfusion : a case report
    In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 3, S. 138 – 139
  • Korfel, Agnieszka; Thiel, Eckhard; Martus, Peter; Möhle, Robert; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Mergenthaler, Hans-Günther; Junghanss, Christian; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Plasswilm, Ludwig; Naegele, Thomas; Pietsch, Torsten; Weller, Michael
    G-PCNSL-SG-1 randomized phase III trial of high-dose methotrexate with or without whole brain radiotherapy for primary central nervous system lymphoma : Long-term follow-up
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 32, 2014, Nr. 15, suppl., S. 8527
    DOI
  • Fischer, L.; Hanel, M.; Mohle, R.; Schroers, R.; Elter, T.; Reiser, M.; Dreyling, M.; Illerhaus, G.; Eucker, J.; Scholz, C.; Metzner, B.; Röth, Alexander; Birkmann, J.; Schlegel, U.; Martus, P.; Thiel, E.; Agnieszka, K.
    First results of a phase II study with combined systemic and intrathecal chemotherapy followed by high-dose chemotherapy for CNS relapse of aggressive lymphomas
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 192
    DOI
  • Korfel, A.; Fischer, L.; Martus, P.; Mohle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Leithauser, M.; Mergenthaler, H. G.; Herrlinger, U.; Weller, M.; Thiel, E.
    Impact of Meningeal Dissemination (MD) on outcome in primary CNS Lymphoma in the G-PCNSL-SG1 Trial
    11th International Conference on Malignant Lymphoma 15-18 June 2011, Lugano (Switzerland),
    In: Annals of Oncology. Amsterdam: Elsevier, Jg. 22, 2011, Nr. Suppl. 4, S. iv92
    DOI (Open Access)
  • Röth, Alexander; Tokareva, O.; Hock, C.; Dührsen, Ulrich
    Management of pregnancy in paroxysmal nocturnal hemoglobinuria (PNH) in the era of eculizumab : A case report and updated review
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 67
    DOI
  • Janson, D.; Fiedler, Melanie; Horacek, Michael; Katsounas, Antonios; Roggendorf, Michael; Dührsen, Ulrich; Röth, Alexander
    Outbreak - pandemic 2009 influenza A (H1N1) infections in a hematology ward : Clinical presentation and outcome
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 43
    DOI
  • Jahnke, K.; Martus, P.; Lokka, S.; Mohle, R.; Griesinger, F.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H. G.; Leithauser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Florschutz, A.; Fischer, L.; Weller, M.; Thiel, E.; Korfel, A.
    Prognostic factors and score for response and survival in primary central nervous system lymphoma from a randomized phase III trial
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 296 – 296
    DOI
  • Jahnke, K.; Martus, P.; Rose, T.; Fischer, L.; Mohle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H. G.; Leithauser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Birkmann, J.; Weller, M.; Thiel, E.; Korfel, A.
    Prognostic factors and scores for chemotherapy-related toxicity in primary central nervous system lymphoma (PCNSL) treated with high-dose methotrexate (HDMTX) with or without ifosfamide : results from a randomized phase III trial
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 295 – 296
    DOI
  • Röth, Alexander; Hock, C.; Tokareva, O.; Konik, A.; Dührsen, Ulrich
    Role of bone marrow failure in paroxysmal nocturnal hemoglobinuria (PNH) patients chronically treated with Eculizumab
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie. Basel: Karger, Jg. 34, 2011, Nr. Suppl. 6, S. 115
    DOI
  • Röth, Alexander; Hüttmann, Andreas; Dührsen, Ulrich
    DECADE Trial : Inhibition of theterminal complement system using the anti-C5 antibody eculizumab for the treatment of cold agglutinin disease (CAD)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 112
    DOI
  • Gothert, Joachim Rudolf; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Fuhrer, Anja; Sellmann, Ludger; Röth, Alexander; Dührsen, Ulrich; Pircher, Hanspeter; Dürig, Jan
    Expanded CLL CD8(+) T-Cells Are Driven Into a Senescent KLRG1(+) Effector Memory Phenotype
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 116, 2010, Nr. 21, S. 403
  • Konik, A.; Dührsen, Ulrich; Röth, Alexander
    Nodular lesions of the scalp and a mediastinal mass in T-cell acute lymphoblastic leukemia (T-ALL)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 238
    DOI
  • Röth, Alexander; de Beer, D.; Porret, N.; Leibundgut, O. E.; Dührsen, Ulrich; Baerlocher, G.
    Telomere length measurement by automated multicolor flow-FISH identifies patients with an inherited Bone Marrow Failure (BMF)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 48 – 49
    DOI

    • Beiträge in Sammelwerken und Tagungsbänden

  • Röth, Alexander; Baerlocher, Gabriela M.; Harley, Calvin B.
    Imetelstat (GRN163L) - Telomerase-Based Cancer Therapy
    In: Recent Results in Cancer Research / Schlag, Peter M.; Senn, Hans-Jörg (Hrsg.). Berlin [u.a.]: Springer, 2010, S. 221 – 234
    DOI

    • Bücher/Sammelwerke/Tagungsbände

  • Röth, Alexander
    Telomere und Telomerase bei physiologischen und pathologischen Zuständen des hämatopoietischen Systems
    Duisburg, Essen, 2011

    • Poster / Posterbeiträge

  • D'Sa, Shirley; Vos, Josephine M.I.; Barcellini, Wilma; Wardęcki, Marek; Perrin, Laurent; Barker, Graham; Zilberstein, Moshe; Storek, Michael; Chow, Timothy; Röth, Alexander
    Classical Complement Inhibition By SAR445088 (BIVV020) in Adults with Cold Agglutinin Disease : Safety, Tolerability and Activity Results from the Open-Label, Non-Randomized, Single-Dose Phase 1b Study
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 142, 2023, Nr. Supplement 1, S. 1069 – 1071
    DOI (Open Access)
  • Poppenborg, Friederike; Pöttgen, Christoph; Möller-Hartmann, Claudia; Schneider, Artur; Reinhardt, H. Christian; Röth, Alexander; Alashkar, Ferras
    Intraspinal extramedullary hematopoietic mass (EMH) in a luspatercept-treated patient with transfusion-dependent beta-thalassemia (TDT)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DHGO Abstracts, S. 299 – 300
    DOI (Open Access)
  • Röth, Alexander; Kuter, D.; Piatek, C.; Dummer, W.
    Phase 3, Randomized, Double-Blind, Placebo-Controlled, Global Study (FORWARD) of Fostamatinib for the Treatment of Warm Antibody Autoimmune Hemolytic Anemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 295
    DOI (Open Access)
  • Röth, Alexander; Broome, C. M.; Barcellini, W.; Weitz, I. C.; et al.
    Sutimlimab provides sustained improvements in patient-reported outcomes and quality of life in patients with cold agglutinin disease : open-label extension of the randomized, Phase 3 CADENZA Study
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 297
    DOI (Open Access)
  • Röth, Alexander; Scheinberg, P.; Villa Cle, D.; Kulasekararaj, A.; et al.
    The phase III randomized, multicenter commodore 1 trial : comparison of crovalimab vs eculizumab in complement inhibitor-experienced patients with paroxysmal nocturnal hemoglobinuria (PNH)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 200 – 201
    DOI (Open Access)
  • Röth, Alexander; He, G.; Brodsky, A.; Han, B.; et al.
    The phase III, randomized, multicenter commodore 2 trial : results from the study of crovalimab vs eculizumab in paroxysmal nocturnal hemoglobinuria (PNH) patients naive to complement inhibitors
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 46, 2023, Nr. Supplement 5: DGHO Abstracts, S. 294 – 295
    DOI (Open Access)
  • Röth, Alexander; Dingli, D.; Mahajerin, A.; Savage, J.; Al-Adhami, M.; Yeh, M.; Birhiray, R.
    Analyse der Persistenz der Anämie und damit verbundener unerwünschter Ereignisse bei Patienten mit paroxysmaler nächtlicher Hämoglobinurie, die mit Pegcetacoplan behandelt wurden
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 233
    DOI (Open Access)
  • Risitano, Antonio; Peffault de Latour, Régis; Yap, Eng Soo; Wong, Lily LL; Ko, Bor-Sheng; Yoon, Sung-Soo; Roeth, Alexander; Baltcheva, Irina; Milojevic, Julie; Fagan, Niamh; Kulmatycki, Kenneth; Nidamarthy, Prasanna K; Junge, Guido; Jang, Jun Ho
    Dose-Exposure-Response Relationships of Biomarkers and Efficacy Measures with Iptacopan, a Complement Factor B Inhibitor, in Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) with or without Concomitant Anti-C5 Therapy
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1, S. 5803 – 5804
    DOI (Open Access)
  • Patriquin, Christopher J.; Bogdanovic, Andrija; Griffin, Morag; Kelly, Richard; Maciejewski, Jaroslaw P.; Mulherin, Brian; Peffault de Latour, Régis; Roeth, Alexander; Selvaratnam, Veena; Szer, Jeffrey; Savage, Jessica; Horneff, Regina; Tan, Lisa; Yeh, Michael; Panse, Jens
    Long-Term Safety and Efficacy of Pegcetacoplan Treatment in Adults with Paroxysmal Nocturnal Hemoglobinuria
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1, S. 2921 – 2923
    DOI (Open Access)
  • Roeth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Wang, Jennifer; Vagge, Deepthi; Wardecki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.
    Sustained Complement C1s Inhibition with Sutimlimab in Patients with Cold Agglutinin Disease Results in Continued Efficacy during Part B of the Randomized Placebo-Controlled Phase 3 Cadenza Study (NCT03347422)
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 140, 2022, Nr. Supplement 1, S. 2825 – 2827
    DOI (Open Access)
  • Blandino, Peter; de Latour, Régis Peffault; Szer, Jeffrey; Ilene, Weitz; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; de Castro, Carlos; Nishimori, Hisakazu; Tan, Lisa; Al-Adhami, Mohammed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio; Hillmen, Peter
    Forty-Eight Week Efficacy and Safety of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria and Suboptimal Response to Prior Eculizumab Treatment
    Society for the Advancement of Patient Blood Management 2021 Annual Meeting PBM Rocks! Virtual Meeting,
    In: Anesthesia & Analgesia. Hagerstown: International Anesthesia Research Society (IARS), Jg. 133, 2021, Nr. 3S, S. 6 – 7
    Online Volltext (Open Access)
  • Röth, Alexander; Peffault de Latour, R.; Szer, J.; Weitz, I.; Höchsmann, B.; Panse, J.; Usuki, K.; Griffin, M.; Kiladijan, J.-J.; De Castro, C. M.; Nishimori, H.; Tan, L.; Al-Adhami, M.; Deschatelets, P.; Francois, C.; Grossi, F.; Risitano, A.; Hillmen, P.
    Forty-eight week efficacy and safety of pegcetacoplan in adult patients with paroxysmal nocturnal hemoglobinuria and suboptimal response to prior eculizumab treatment
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 44, 2021, Nr. Supplement 2, S. 169
    DOI (Open Access)
  • Röth, Alexander; Lenderking, William R.; Sarda, Sujata P.; Baver, Scott B.; Hamdani, Mohamed; Hsieh, Ray; Shaffer, Shannon; Yeh, Michael; Cella, David
    Improvements in Fatigue and Physical Function Evaluated Through Changes in Clinical Outcomes in Paroxysmal Nocturnal Hemoglobinuria : Post-Hoc Analyses from the PEGASUS Study
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 193, 2021, Nr. S1, S. 77 – 232
    DOI, Online Volltext (Open Access)
  • Röth, Alexander; Barcellini, W.; D’Sa, S.; Miyakawa, Y.; Broome, C.; Michel, M.; Kuter, D.; Jilma, B.; Tvedt, T. H. A.; Weitz, I. C.; Patel, P.; Jiang, X.; Reuter, C.; Su, J.; Shafer, F.; Lee, M.; Hobbs, W.; Berentsen, S.
    Interim results of the phase 3 CARDINAL study long-term follow-up: Inhibition of complement C1s with sutimlimab in patients with Cold Agglutinin Disease (CAD)
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 44, 2021, Nr. Supplement 2, S. 169 – 170
    DOI (Open Access)
  • Risitano, A.; Munir, T.; Jang, J. Ho; Lee, G.-W.; Wanachiwanawin, W.; Schrezenmeier, H.; Yonemura, Y.; Pavani, R.; Wang, J.; Kulagin, A.; Kulasekararaj, A.; de Fontbrune, F. Sicre; Röth, Alexander
    Transfusion requirements in adult patients with paroxysmal nocturnal hemoglobinuria with or without a history of bone marrow disorder receiving ravulizumab and eculizumab : results from a phase 3 non-inferiority study extension
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology. Hoboken: Wiley-Blackwell - STM, Jg. 193, 2021, Nr. S1, S. 203 – 204
    DOI (Open Access)