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Prof. Dr. rer. nat. Ralf Küppers

Telefon
+49 201 723 3384
E-Mail
Ralf.Kueppers@uk-essen.de
Webseite
http://www.uni-due.de/home/fb/ifz/forschung/amg/de_startseite.shtml

Funktionen

  • Universitätsprofessor/in, Institut für Zellbiologie (Tumorforschung)

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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Johansson, Patricia; Klein-Hitpaß, Ludger; Budeus, Bettina; Kuhn, Matthias; Lauber, Chris; Seifert, Michael; Roeder, Ingo; Pförtner, Roman; Stuschke, Martin; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencing
    In: Cancers Jg. 12 (2020) Nr. 4, S. 986
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/
  • Thurner, Lorenz; Hartmann, Sylvia; Fadle, Natalie; Regitz, Evi; Kemele, Maria; Kim, Yoo-Jin; Bohle, Rainer Maria; Nimmesgern, Anna; von Müller, Lutz; Kempf, Volkhard A. J.; Weniger, Marc; Neumann, Frank; Schneider, Nadine; Vornanen, Martine; Sundström, Christer; de Leval, Laurence; Engert, Andreas; Eichenauer, Dennis A.; Küppers, Ralf; Preuss, Klaus-Dieter; Hansmann, Martin-Leo; Pfreundschuh, Michael
    Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma
    In: Nature Communications Jg. 11 (2020) Nr. 1, S. 2465
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/
  • Küppers, Ralf; Schadendorf, Dirk; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium; et al.
    Pan-cancer analysis of whole genomes
    In: Nature Jg. 578 (2020) Nr. 7793, S. 82 - 93
    ISSN: 0028-0836; 1476-4687
    Online Volltext: dx.doi.org/
  • Janssen, Anke; Villacorta Hidalgo, Jose; Beringer, Dennis X.; van Dooremalen, Sanne; Fernando, Febilla; van Diest, Eline; Terrizi, Antonela R.; Bronsert, Peter; Kock, Sylvia; Schmitt-Gräff, Annette; Werner, Martin; Heise, Kerstin; Follo, Marie; Straetemans, Trudy; Sebestyen, Zsolt; Chudakov, Dmitry M.; Kasatskaya, Sofya A.; Frenkel, Felix E.; Ravens, Sarina; Spierings, Eric; Prinz, Immo; Küppers, Ralf; Malkovsky, Miroslav; Fisch, Paul; Kuball, Jürgen
    γδ T-cell receptors derived from breast cancer-infiltrating T lymphocytes mediate antitumor reactivity
    In: Cancer immunology research: illuminating the interplay of cancer and the immune system Jg. 8 (2020) Nr. 4, S. 530 - 543
    ISSN: 2326-6074
    Online Volltext: dx.doi.org/
  • Hartmann, Sylvia; Goncharova, Olga; Portyanko, Anna; Sabattini, Elena; Meinel, Jörn; Küppers, Ralf; Agostinelli, Claudio; Pileri, Stefano Aldo; Hansmann, Martin-Leo
    CD30 expression in neoplastic T cells of follicular T cell lymphoma is a helpful diagnostic tool in the differential diagnosis of Hodgkin lymphoma
    In: Modern Pathology Jg. 32 (2019) Nr. 1, S. 37 - 47
    ISSN: 1530-0285; 0893-3952
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    CD81 as target for B cell lymphomas
    In: Journal of Experimental Medicine (JEM) Jg. 216 (2019) Nr. 7, S. 1469 - 1470
    ISSN: 1540-9538; 0022-1007
    Online Volltext: dx.doi.org/
  • Bankov, Katrin; Döring, Claudia; Ustaszewski, Adam; Giefing, Maciej; Herling, Marco; Cencioni, Chiara; Spallotta, Francesco; Gaetano, Carlo; Küppers, Ralf; Hansmann, Martin-Leo; Hartmann, Sylvia
    Fibroblasts in nodular sclerosing classical Hodgkin lymphoma are defined by a specific phenotype and protect tumor cells from brentuximab-Vedotin induced injury
    In: Cancers Jg. 11 (2019) Nr. 11,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/
  • López, Cristina; Kleinheinz, Kortine; Aukema, Sietse M.; Rohde, Marius; Bernhart, Stephan H.; Hübschmann, Daniel; Wagener, Rabea; Toprak, Umut H.; Raimondi, Francesco; Kreuz, Markus; Waszak, Sebastian M.; Huang, Zhiqin; Sieverling, Lina; Paramasivam, Nagarajan; Seufert, Julian; Sungalee, Stephanie; Russell, Robert B.; Bausinger, Julia; Kretzmer, Helene; Ammerpohl, Ole; Bergmann, Anke K.; Binder, Hans; Borkhardt, Arndt; Brors, Benedikt; Claviez, Alexander; Doose, Gero; Feuerbach, Lars; Haake, Andrea; Hansmann, Martin-Leo; Hoell, Jessica; Hummel, Michael; Korbel, Jan O.; Lawerenz, Chris; Lenze, Dido; Radlwimmer, Bernhard; Richter, Julia; Rosenstiel, Philip; Rosenwald, Andreas; Schilhabel, Markus B.; Stein, Harald; Stilgenbauer, Stephan; Stadler, Peter F.; Szczepanowski, Monika; Weniger, Marc; Zapatka, Marc; Eils, Roland; Lichter, Peter; Loeffler, Markus; Möller, Peter; Trümper, Lorenz; Klapper, Wolfram; Wagner, Susanne; Richter, Gesine; Eils, Jürgen; Kerssemakers, Jules; Jaeger-Schmidt, Christina; Scholz, Ingrid; Borst, Christoph; Braulke, Friederike; Dreyling, Martin; Eberth, Sonja; Einsele, Hermann; Frickhofen, Norbert; Haas, Siegfried; Karsch, Dennis; Klepl, Nicole; Kneba, Michael; Lisfeld, Jasmin; Mantovani-Löffler, Luisa; Ott, German; Stadler, Christina; Staib, Peter; Zenz, Thorsten; Kube, Dieter; Kostezka, Ulrike; Binder, Vera; Leich, Ellen; Nagel, Inga; Pischimariov, Jordan; Schreiber, Stefan; Vater, Inga; Hopp, Lydia; Langenberger, David; Rosolowski, Maciej; Hoffmann, Steve; Küppers, Ralf; Burkhardt, Birgit; Schlesner, Matthias; Siebert, Reiner
    Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma
    In: Nature Communications Jg. 10 (2019) Nr. 1, S. 1459
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/
  • Schuhmacher, Bianca; Bein, Julia; Rausch, Tobias; Benes, Vladimir; Tousseyn, Thomas; Vornanen, Martine; Ponzoni, Maurilio; Thurner, Lorenz; Gascoyne, Randy; Steidl, Christian; Küppers, Ralf; Hansmann, Martin-Leo; Hartmann, Sylvia
    JUNB, DUSP2, SGK1, SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma
    In: Haematologica Jg. 104 (2019) Nr. 2, S. 330 - 337
    ISSN: 1592-8721
    Online Volltext: dx.doi.org/
  • Hüllein, Jennifer; Słabicki, Mikołaj; Rosolowski, Maciej; Jethwa, Alexander; Habringer, Stefan; Tomska, Katarzyna; Kurilov, Roma; Lu, Junyan; Scheinost, Sebastian; Wagener, Rabea; Huang, Zhiqin; Lukas, Marina; Yavorska, Olena; Helfrich, Hanne; Scholtysik, René; Bonneau, Kyle; Tedesco, Donato; Küppers, Ralf; Klapper, Wolfram; Pott, Christiane; Stilgenbauer, Stephan; Burkhardt, Birgit; Löffler, Markus; Trümper, Lorenz H.; Hummel, Michael; Brors, Benedikt; Zapatka, Marc; Siebert, Reiner; Kreuz, Markus; Keller, Ulrich; Huber, Wolfgang; Zenz, Thorsten
    MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma
    In: Cancer Research Jg. 79 (2019) Nr. 12, S. 3125 - 3138
    ISSN: 1538-7445; 0008-5472
    Online Volltext: dx.doi.org/
  • Goncharova, Olga; Flinner, Nadine; Bein, Julia; Döring, Claudia; Donnadieu, Emmanuel; Rikirsch, Sandy; Herling, Marco; Küppers, Ralf; Hansmann, Martin-Leo; Hartmann, Sylvia
    Migration properties distinguish tumor cells of classical hodgkin lymphoma from anaplastic large cell lymphoma cells
    In: Cancers Jg. 11 (2019) Nr. 10, S. 1484
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/
  • Seifert, Marc; Scholtysik, René; Küppers, Ralf
    Origin and Pathogenesis of B Cell Lymphomas
    In: Methods in Molecular Biology Jg. 1956 (2019) S. 1 - 33
    ISSN: 1940-6029; 1064-3745
    Online Volltext: dx.doi.org/
  • Lollies, Anna; Hartmann, Sylvia; Schneider, Markus; Bracht, Thilo; Weiß, A.L.; Arnolds, Judith; Klein-Hitpaß, Ludger; Sitek, Barbara; Hansmann, Martin Leo; Küppers, Ralf; Weniger, Marc
    An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphoma
    In: Leukemia Jg. 32 (2018) Nr. 1, S. 92 - 101
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Tucci, Felicia A.; Kitanovski, Simo; Johansson, Patricia; Klein-Hitpaß, Ludger; Kahraman, Alisan; Dürig, Jan; Hoffmann, Daniel; Küppers, Ralf
    Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individuals
    In: Blood Jg. 131 (2018) Nr. 5, S. 546 - 557
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    CD83 in Hodgkin lymphoma
    In: Haematologica Jg. 103 (2018) Nr. 4, S. 561 - 562
    ISSN: 1592-8721; 0390-6078
    Online Volltext: dx.doi.org/
  • Küppers, Ralf; Stevenson, Freda K.
    Critical influences on the pathogenesis of follicular lymphoma
    In: Blood Jg. 131 (2018) Nr. 21, S. 2297 - 2306
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Weiser, Christian; Petkova, Mina V.; Rengstl, Benjamin; Döring, Claudia; von Laer, Dorothee; Hartmann, Sylvia; Küppers, Ralf; Hansmann, Martin-Leo; Newrzela, Sebastian
    Ectopic expression of transcription factor BATF3 induces B-cell lymphomas in a murine B-cell transplantation model
    In: OncoTarget Jg. 9 (2018) Nr. 22, S. 15942 - 15951
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/
  • Unterluggauer, Julia J.; Prochazka, Katharina; Tomazic, Peter V.; Huber, Heinrich J.; Seeboeck, Rita; Fechter, Karoline; Steinbauer, Elisabeth; Gruber, Verena; Feichtinger, Julia; Pichler, Martin; Weniger, Marc; Küppers, Ralf; Sill, Heinz; Schicho, Rudolf; Neumeister, Peter; Beham-Schmid, Christine; Deutsch, Alexander J. A.; Haybaeck, Johannes
    Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome.
    In: Blood Cancer Journal Jg. 8 (2018) Nr. 9, S. 79
    ISSN: 2044-5385
    Online Volltext: dx.doi.org/
  • Weniger, Marc; Tiacci, Enrico; Schneider, Stefanie; Arnolds, Judith; Rüschenbaum, Sabrina; Duppach, Janine; Seifert, Marc; Döring, Claudia; Hansmann, Martin-Leo; Küppers, Ralf
    Human CD30⁺ B cells represent a unique subset related to Hodgkin lymphoma cells
    In: The Journal of Clinical Investigation (JCI) Jg. 128 (2018) Nr. 7, S. 2996 - 3007
    ISSN: 1558-8238; 0021-9738
    Online Volltext: dx.doi.org/ Online Volltext
  • Wagener, Rabea; López, Cristina; Kleinheinz, Kortine; Bausinger, Julia; Aukema, Sietse M.; Nagel, Inga; Toprak, Umut H.; Seufert, Julian; Altmüller, Janine; Thiele, Holger; Schneider, Christof; Kolarova, Julia; Park, Jeongbin; Hübschmann, Daniel; Murga Penas, Eva M.; Drexler, Hans G.; Attarbaschi, Andishe; Hovland, Randi; Kjeldsen, Eigil; Kneba, Michael; Kontny, Udo; de Leval, Laurence; Nürnberg, Peter; Oschlies, Ilske; Oscier, David; Schlegelberger, Brigitte; Stilgenbauer, Stephan; Wössmann, Wilhelm; Schlesner, Matthias; Burkhardt, Birgit; Klapper, Wolfram; Jaffe, Elaine S.; Küppers, Ralf; Siebert, Reiner
    IG-MYC⁺ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas
    In: Blood Jg. 132 (2018) Nr. 21, S. 2280 - 2285
    ISSN: 1528-0020
    Online Volltext: dx.doi.org/
  • Wierzbinska, Justyna Anna; Toth, Reka; Ishaque, Naveed; Mallm, Jan-Phillip; Rippe, Karsten; Mertens, Daniel; Hielscher, Thomas; Zenz, Thorsten; Seifert, Marc; Küppers, Ralf; Assenov, Yassen; Stilgenbauer, Stephan; Byrd, John C.; Oakes, Christopher C.; Lipka, Daniel B.; Plass, Christoph;
    Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood Jg. 132 (2018) Nr. Supplement 1, S. 3885 - 3885
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Choidas, Axel; Habenberger, Peter; Mahboubi, Bijan; Kim, Baek; Bergmann, Anke; Scholtysik, René; Brauser, Martina; Lollies, Anna; Siebert, Reiner; Zenz, Thorsten; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia
    In: Blood Cancer Journal Jg. 8 (2018) Nr. 1, S. 11
    ISSN: 2044-5385
    Online Volltext: dx.doi.org/ Online Volltext
  • Johansson, Patricia; Habenberger, Peter; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Küppers, Ralf; Schultz-Fademrecht, Carsten; Choidas, Axel; Dürig, Jan
    CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in Vitro
    In: Blood Jg. 130 (2017) Nr. Suppl. 1, S. 1262
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Wein, Frederik; Weniger, Marc; Höing, Benedikt; Arnolds, Judith; Hüttmann, Andreas; Hansmann, Martin-Leo; Hartmann, Sylvia; Küppers, Ralf
    Complex Immune Evasion Strategies in Classical Hodgkin Lymphoma
    In: Cancer Immunology Research Jg. 5 (2017) Nr. 12, S. 1122 - 1132
    ISSN: 2326-6074; 2326-6066
    Online Volltext: dx.doi.org/
  • Herling, Marco; Rengstl, Benjamin; Scholtysik, René; Hartmann, Sylvia; Küppers, Ralf; Hansmann, Martin-Leo; Diebner, Hans H.; Roeder, Ingo; Abken, Hinrich; Newrzela, Sebastian; Kirberg, Jörg
    Concepts in mature T-cell lymphomas – highlights from an international joint symposium on T-cell immunology and oncology
    In: Leukemia and Lymphoma Jg. 58 (2017) Nr. 4, S. 788 - 796
    ISSN: 1029-2403; 1042-8194
    Online Volltext: dx.doi.org/
  • Saeedghalati, Mohammadkarim; Farahpour, Farnoush; Budeus, Bettina; Lange, Anja; Westendorf, Astrid; Seifert, Marc; Küppers, Ralf; Hoffmann, Daniel
    Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to Microbiomes
    In: PLoS Computational Biology Jg. 13 (2017) Nr. 1, S. e1005362
    ISSN: 1553-734X; 1553-7358
    Online Volltext: dx.doi.org/ Online Volltext
  • Küppers, Ralf
    Structure and diversification of immunoglobulin genes in African Burkitt lymphoma
    In: Blood Advances Jg. 1 (2017) Nr. 16, S. 1259 - 1260
    ISSN: 2473-9537; 2473-9529
    Online Volltext: dx.doi.org/
  • Schwartz, Friederike H; Cai, Qian; Fellmann, Eva; Hartmann, Sylvia; Mäyränpää, Mikko I.; Karjalainen-Lindsberg, Marja-Liisa; Sundström, Christer; Scholtysik, René; Hansmann, Martin-Leo; Küppers, Ralf
    TET2 mutations in B cells of patients affected by angioimmunoblastic T-cell lymphoma
    In: The Journal of Pathology Jg. 242 (2017) Nr. 2, S. 129 - 133
    ISSN: 0022-3417; 1096-9896
    Online Volltext: dx.doi.org/
  • Schuhmacher, Bianca; Rengstl, Benjamin; Döring, Claudia; Bein, Julia; Newrzela, Sebastian; Brunnberg, Uta; Kvasnicka, Hans Michael; Vornanen, Martine; Küppers, Ralf; Hansmann, Martin-Leo; Hartmann, Sylvia
    A strong host response and lack of MYC expression are characteristic for diffuse large B cell lymphoma transformed from nodular lymphocyte predominant Hodgkin lymphoma
    In: OncoTarget Jg. 7 (2016) Nr. 44, S. 72197 - 72210
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/
  • Hezaveh, Kebria; Kloetgen, Andreas; Bernhart, Stephan H; Mahapatra, Kunal Das; Lenze, Dido; Richter, Julia; Haake, Andrea; Bergmann, Anke K; Brors, Benedikt; Burkhardt, Birgit; Claviez, Alexander; Drexler, Hans G; Eils, Roland; Haas, Siegfried; Hoffmann, Steve; Karsch, Dennis; Klapper, Wolfram; Kleinheinz, Kortine; Korbel, Jan; Kretzmer, Helene; Kreuz, Markus; Küppers, Ralf; Lawerenz, Chris; Leich, Ellen; Loeffler, Markus; Mantovani-Loeffler, Luisa; López, Cristina; McHardy, Alice C; Möller, Peter; Rohde, Marius; Rosenstiel, Philip; Rosenwald, Andreas; Schilhabel, Markus; Schlesner, Matthias; Scholz, Ingrid; Stadler, Peter F; Stilgenbauer, Stephan; Sungalee, Stéphanie; Szczepanowski, Monika; Trümper, Lorenz; Weniger, Marc; Siebert, Reiner; Borkhardt, Arndt; Hummel, Michael; Hoell, Jessica I
    Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis
    In: Haematologica Jg. 101 (2016) Nr. 11, S. 1380 - 1389
    ISSN: 0390-6078; 1592-8721
    Online Volltext: dx.doi.org/
  • Oakes, Christopher C; Seifert, Marc; Assenov, Yassen; Gu, Lei; Przekopowitz, Martina; Ruppert, Amy S; Wang, Qi; Imbusch, Charles D; Serva, Andrius; Koser, Sandra D; Brocks, David; Lipka, Daniel B; Bogatyrova, Olga; Weichenhan, Dieter; Brors, Benedikt; Rassenti, Laura; Kipps, Thomas J; Mertens, Daniel; Zapatka, Marc; Lichter, Peter; Döhner, Hartmut; Küppers, Ralf; Zenz, Thorsten; Stilgenbauer, Stephan; Byrd, John C; Plass, Christoph
    DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
    In: Nature Genetics Jg. 48 (2016) Nr. 3, S. 253 - 264
    ISSN: 1061-4036; 1546-1718
    Online Volltext: dx.doi.org/ Online Volltext
  • Mansouri, Larry; Noerenberg, Daniel; Young, Emma; Mylonas, Elena; Abdulla, Maysaa; Frick, Mareike; Asmar, Fazila; Ljungström, Viktor; Schneider, Markus; Yoshida, Kenichi; Skaftason, Aron; Pandzic, Tatjana; Gonzalez, Blanca; Tasidou, Anna; Waldhueter, Nils; Rivas-Delgado, Alfredo; Angelopoulou, Maria; Ziepert, Marita; Arends, Christopher Maximilian; Couronné, Lucile; Lenze, Dido; Baldus, Claudia D; Bastard, Christian; Okosun, Jessica; Fitzgibbon, Jude; Dörken, Bernd; Drexler, Hans G; Roos-Weil, Damien; Schmitt, Clemens A; Munch-Petersen, Helga D; Zenz, Thorsten; Hansmann, Martin-Leo; Strefford, Jonathan C; Enblad, Gunilla; Bernard, Olivier A; Ralfkiaer, Elisabeth; Erlanson, Martin; Korkolopoulou, Penelope; Hultdin, Magnus; Papadaki, Theodora; Grønbæk, Kirsten; Lopez-Guillermo, Armando; Ogawa, Seishi; Küppers, Ralf; Stamatopoulos, Kostas; Stavroyianni, Niki; Kanellis, George; Rosenwald, Andreas; Campo, Elias; Amini, Rose-Marie; Ott, German; Vassilakopoulos, Theodoros P; Hummel, Michael; Rosenquist, Richard; Damm, Frederik
    Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
    In: Blood Jg. 128 (2016) Nr. 23, S. 2666 - 2670
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Hartmann, S; Schuhmacher, B; Rausch, T; Fuller, L; Döring, C; Weniger, Marc; Lollies, A; Weiser, C; Thurner, L; Rengstl, B; Brunnberg, U; Vornanen, M; Pfreundschuh, M; Benes, V; Küppers, Ralf; Newrzela, S; Hansmann, M-L
    Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma
    In: Leukemia Jg. 30 (2016) Nr. 4, S. 844 - 853
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Mathas, Stephan; Hartmann, Sylvia; Küppers, Ralf
    Hodgkin lymphoma : Pathology and biology
    In: Seminars in Hematology Jg. 53 (2016) Nr. 3, S. 139 - 147
    ISSN: 0037-1963
    Online Volltext: dx.doi.org/
  • Seifert, M; Küppers, Ralf
    Human memory B cells
    In: Leukemia Jg. 30 (2016) Nr. 12, S. 2283 - 2292
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Schreiber, Fedor; Kahnert, Stefan; Goehlich, Andreas; Greifendorf, Dieter; Bartels, Frank; Janzyk, Udo; Lennartz, Klaus; Kirstein, Uwe; Rennings, Andreas; Küppers, Ralf; Erni, Daniel
    Mikrofluidik-Chip-Architekturen für eine Zell-Sortieranlage basierend auf der Elektrowetting-Technologie
    In: Technisches Messen: tm Jg. 83 (2016) Nr. 5, S. 274 - 288
    ISSN: 0171-8096
    Online Volltext: dx.doi.org/
  • Weniger, Marc; Küppers, Ralf
    NF-κB deregulation in Hodgkin lymphoma
    In: Seminars in Cancer Biology Jg. 39 (2016) S. 32 - 39
    ISSN: 1044-579X; 1096-3650
    Online Volltext: dx.doi.org/
  • Otto, Claudia; Scholtysik, René; Schmitz, Roland; Kreuz, Markus; Becher, Claudia; Hummel, Michael; Rosenwald, Andreas; Trümper, Lorenz; Klapper, Wolfram; Siebert, Reiner; Küppers, Ralf
    Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas
    In: Genes, Chromosomes and Cancer Jg. 55 (2016) Nr. 12, S. 932 - 943
    ISSN: 1045-2257; 1098-2264
    Online Volltext: dx.doi.org/
  • Johansson, Patricia; Bergmann, Anke; Rahmann, Sven; Wohlers, Inken; Scholtysik, René; Przekopowitz, Martina; Seifert, Marc; Tschurtschenthaler, Gertraud; Webersinke, Gerald; Jäger, Ulrich; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia
    In: International Journal of Cancer Jg. 138 (2016) Nr. 1, S. 121 - 124
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Grabellus, Florian; Arnold, Georg; Klapper, Wolfram; Pförtner, Roman; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas
    In: OncoTarget Jg. 7 (2016) Nr. 38, S. 62627 - 62639
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/
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    The International Human Epigenome Consortium : A Blueprint for Scientific Collaboration and Discovery
    In: Cell Jg. 167 (2016) Nr. 5, S. 1145 - 1149
    ISSN: 0092-8674
    Online Volltext: dx.doi.org/
  • Wein, Frederik; Küppers, Ralf
    The role of t cells in the microenvironment of hodgkin lymphoma
    In: Journal of Leukocyte Biology Jg. 99 (2016) Nr. 1, S. 45 - 50
    ISSN: 1938-3673; 0741-5400
    Online Volltext: dx.doi.org/ Online Volltext
  • Rengstl, Benjamin; Schmid, Frederike; Weiser, Christian; Döring, Claudia; Heinrich, Tim; Warner, Kathrin; Becker, Petra S A; Wistinghausen, Robin; Kameh-Var, Sima; Werling, Eva; Billmeier, Arne; Seidl, Christian; Hartmann, Sylvia; Abken, Hinrich; Küppers, Ralf; Hansmann, Martin-Leo; Newrzela, Sebastian
    Tumor-infiltrating HLA-matched CD4(+) T cells retargeted against Hodgkin and Reed-Sternberg cells
    In: OncoImmunology Jg. 5 (2016) Nr. 6, S. e1160186
    ISSN: 2162-4011; 2162-402X
    Online Volltext: dx.doi.org/
  • Przekopowitz, Martina; Küppers, Ralf; Weniger, Marc
    A large fraction of human tonsillar B cells expressing CD27 are germinal center B cells
    In: Immunology and Cell Biology Jg. 93 (2015) Nr. 5, S. 429 - 430
    ISSN: 0818-9641; 1440-1711
    Online Volltext: dx.doi.org/
  • Schneider, Markus; Schneider, Stefanie; Zühlke-Jenisch, Reina; Klapper, Wolfram; Sundström, Christer; Hartmann, Sylvia; Hansmann, Martin-Leo; Siebert, Reiner; Küppers, Ralf; Giefing, Maciej
    Alterations of the CD58 gene in classical Hodgkin lymphoma
    In: Genes, Chromosomes and Cancer Jg. 54 (2015) Nr. 10, S. 638 - 645
    ISSN: 1045-2257; 1098-2264
    Online Volltext: dx.doi.org/
  • Huellein, J.; Slabicki, M.; Rosolowski, M.; Scholtysik, R.; Jethwa, A.; Lukas, M.; Tomska, K.; Helfrich, H.; Siebert, R.; Küppers, Ralf; Hummel, M.; Klapper, W.; Stilgenbauer, S.; Kreuz, M.; Loeffler, M.; Truemper, L.; von Kalle, C.; Zenz, T.
    Analysis of mechanisms of malignant transformation in TP53 wild-type burkitts lymphoma by integration of molecular and functional genomics data
    In: Haematologica Jg. 100 (2015) Nr. Suppl. 1, S. 105
    ISSN: 1592-8721; 0390-6078
    Online Volltext
  • Scholtysik, Rene; Kreuz, Markus; Hummel, Michael; Rosolowski, Maciej; Szczepanowski, Monika; Klapper, Wolfram; Loeffler, Markus; Trümper, Lorenz; Siebert, Reiner; Küppers, Ralf
    Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis
    In: International Journal of Cancer Jg. 136 (2015) Nr. 5, S. 1033 - 1042
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Budeus, Bettina; De Reynoso, Stefanie Schweigle; Przekopowitz, Martina; Hoffmann, Daniel; Seifert, Marc; Küppers, Ralf
    Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5281 - E5289
    ISSN: 1091-6490; 0027-8424
    Online Volltext: dx.doi.org/
  • Kretzmer, Helene; Bernhart, Stephan H; Wang, Wei; Haake, Andrea; Weniger, Marc; Bergmann, Anke K; Betts, Matthew J; Carrillo-de-Santa-Pau, Enrique; Doose, Gero; Gutwein, Jana; Richter, Julia; Hovestadt, Volker; Huang, Bingding; Rico, Daniel; Jühling, Frank; Kolarova, Julia; Lu, Qianhao; Otto, Christian; Wagener, Rabea; Arnolds, Judith; Burkhardt, Birgit; Claviez, Alexander; Drexler, Hans G; Eberth, Sonja; Eils, Roland; Flicek, Paul; Haas, Siegfried; Hummel, Michael; Karsch, Dennis; Kerstens, Hinrik H D; Klapper, Wolfram; Kreuz, Markus; Lawerenz, Chris; Lenze, Dido; Loeffler, Markus; López, Cristina; MacLeod, Roderick A F; Martens, Joost H A; Kulis, Marta; Martín-Subero, José Ignacio; Möller, Peter; Nagel, Inga; Picelli, Simone; Vater, Inga; Rohde, Marius; Rosenstiel, Philip; Rosolowski, Maciej; Russell, Robert B; Schilhabel, Markus; Schlesner, Matthias; Stadler, Peter F; Szczepanowski, Monika; Trümper, Lorenz; Stunnenberg, Hendrik G; Küppers, Ralf; Ammerpohl, Ole; Lichter, Peter; Siebert, Reiner; Hoffmann, Steve; Radlwimmer, Bernhard
    DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
    In: Nature Genetics Jg. 47 (2015) Nr. 11, S. 1316 - 1325
    ISSN: 1061-4036; 1546-1718
    Online Volltext: dx.doi.org/ Online Volltext
  • Seifert, Marc; Przekopowitz, Martina; Taudien, Sarah; Lollies, Anna; Ronge, Viola; Drees, Britta; Lindemann, Monika; Hillen, Uwe; Engler, Harald; Singer, Bernhard B.; Küppers, Ralf
    Functional capacities of human igm memory b cells in early inflammatory responses and secondary germinal center reactions
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 6, S. E546 - E555
    ISSN: 1091-6490; 0027-8424
    Online Volltext: dx.doi.org/
  • Loeffler, M.; Kreuz, M.; Haake, A.; Hasenclever, D.; Trautmann, H.; Arnold, C.; Winter, K.; Koch, K.; Klapper, W.; Scholtysik, R.; Rosolowski, M.; Hoffmann, S.; Ammerpohl, O.; Szczepanowski, M.; Herrmann, D.; Küppers, Ralf; Pott, C.; Siebert, R.
    Genomic and epigenomic co-evolution in follicular lymphomas
    In: Leukemia Jg. 29 (2015) Nr. 2, S. 456 - 463
    ISSN: 1476-5551
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas
    In: Journal of Experimental Medicine (JEM) Jg. 212 (2015) Nr. 13, S. 2184
    ISSN: 0022-1007
    Online Volltext: dx.doi.org/
  • Doose, Gero; Haake, Andrea; Bernhart, Stephan H.; Lopez, Christina; Duggimpudi, Sujitha; Wojciech, Franziska; Bergmann, Anke K.; Borkhardt, Arndt; Burkhardt, Birgit; Claviez, Alexander; Dimitrova, Lora; Haas, Sigfried; Hoell, Jessica; Hummel, Michael; Karsch, Dennis; Klapper, Wolfram; Kleo, Karsten; Kretzmer, Helene; Kreuz, Markus; Küppers, Ralf; Lawerenz, Chris; Lenze, Dido; Loeffler, Markus; Mantovani-Löffler, Luisa; Möller, Peter; Ott, German; Richter, Julia; Rohde, Marius; Rosenstiel, Philip; Rosenwald, Andreas; Schilhabel, Markus; Schneider, Markus; Scholz, Ingrid; Stilgenbauer, Stephan; Stunnenberg, Hendrik G.; Szczepanowski, Monika; Trümper, Lorenz; Weniger, Marc; Hoffmann, Steve; Siebert, Reiner; Iaccarino, Ingram; Eisenman, Robert N.
    MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5261 - E5270
    ISSN: 1091-6490; 0027-8424
    Online Volltext: dx.doi.org/
  • Thurner, L.; Hartmann, S.; Kemele, M.; Regitz, E.; Fadle, N.; Preuss, K. D.; Kim, Y. J.; Bohle, R. M.; Vornanen, M.; Kempf, V. A. J.; von Mueller, L.; Küppers, Ralf; Hansmann, M. L.; Pfreundschuh, M.
    Moraxella Catarrhalis-A bacterial involvement in the origin of nodular lymphocyte predominant Hodgkin Lymphoma of IGD type?
    In: Haematologica Jg. 100 (2015) Nr. Suppl.1, S. 106 - 107
    ISSN: 0390-6078; 1592-8721
  • Wein, Frederik; Otto, Teresa; Lambertz, Pascal; Fandrey, Joachim; Hansmann, Martin-Leo; Küppers, Ralf
    Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis
    In: Haematologica Jg. 100 (2015) Nr. 10, S. 1320 - 1326
    ISSN: 1592-8721; 0390-6078
    Online Volltext: dx.doi.org/
  • Oakes, C. C.; Seifert, Marc; Assenov, Y.; Gu, L.; Przekopowitz, M.; Ruppert, A. S.; Wang, Q.; Imbusch, C.; Serva, A.; Koser, S.; Brocks, D.; Lipka, D. B.; Bogatyrova, O.; Brors, B.; Weichenhan, D.; Rassenti, L. Z.; Kipps, T. J.; Mertens, D.; Zapatka, M.; Lichter, P.; Dohner, H.; Küppers, Ralf; Zenz, T.; Stilgenbauer, S.; Byrd, J. C.; Plass, C.
    Progressive Epigenetic Programming during B Cell Maturation Is Reflected in a Continuum of Epigenetic Disease Phenotypes in Chronic Lymphocytic Leukemia
    In: Blood Jg. 126 (2015) Nr. 23, S. 2436
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Lipka, Daniel; Mertens, Daniel; Ruppert, Amy; Bogatyrova, Olga; Seifert, Marc; Plass, Christoph; Zenz, Thorsten; Stilgenbauer, Stephan; Yassen, Assenov; Küppers, Ralf; Koser, Sandra; Gu, Lei; Doehner, Hartmut; Zapatka, Marc; Oakes, Christopher C.; Byrd, John; Serva, Andrius; Brocks, David; Lichter, Peter; Przekopowitz, Martina
    Progressive epigenetic programming during B cell maturation yields a continuum of clonal disease phenotypes with distinct etiologies in chronic lymphocytic leukemia
    In: Clinical Cancer Research Jg. 21 (2015) Nr. 17 Suppl., S. B25 - B25
    ISSN: 1078-0432
    Online Volltext: dx.doi.org/
  • Peveling-Oberhag, Jan; Wolters, Franziska; Döring, Claudia; Walter, Dirk; Sellmann, Ludger; Scholtysik, René; Lucioni, Marco; Schubach, Max; Paulli, Marco; Biskup, Saskia; Zeuzem, Stefan; Küppers, Ralf; Hansmann, Martin-Leo
    Whole exome sequencing of microdissected splenic marginal zone lymphoma : A study to discover novel tumor-specific mutations
    In: BMC Cancer Jg. 15 (2015) Nr. 1, S. 773
    ISSN: 1471-2407
    Online Volltext: dx.doi.org/
  • Kulis, Marta; Merkel, Angelika; Heath, Simon; Queirós, Ana C.; Schuyler, Ronald P.; Castellano, Giancarlo; Beekman, Renée; Raineri, Emanuele; Esteve, Anna; Clot, Guillem; Verdaguer-Dot, Néria; Duran-Ferrer, Martí; Russiñol, Nuria; Vilarrasa-Blasi, Roser; Ecker, Simone; Pancaldi, Vera; Rico, Daniel; Agueda, Lidia; Blanc, Julie; Richardson, David; Clarke, Laura; Datta, Avik; Pascual, Marien; Agirre, Xabier; Prosper, Felipe; Alignani, Diego; Paiva, Bruno; Caron, Gersende; Fest, Thierry; Muench, Marcus O.; Fomin, Marina E.; Lee, Seung-Tae; Wiemels, Joseph L.; Valencia, Alfonso; Gut, Marta; Flicek, Paul; Stunnenberg, Hendrik G.; Siebert, Reiner; Küppers, Ralf; Gut, Ivo G.; Campo, Elías; Martín-Subero, José I.
    Whole-genome fingerprint of the DNA methylome during human B cell differentiation
    In: Nature Genetics Jg. 47 (2015) Nr. 7, S. 746 - 756
    ISSN: 1061-4036; 1546-1718
    Online Volltext: dx.doi.org/ Online Volltext
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    A microRNA involved in the germinal center reaction
    In: Blood Jg. 124 (2014) Nr. 2, S. 158 - 159
    ISSN: 1528-0020
    Online Volltext: dx.doi.org/ Online Volltext
  • Döring, Claudia; Hansmann, Martin-Leo; Agostinelli, Claudio; Piccaluga, Pier P.; Facchetti, Fabio; Pileri, Stefano; Küppers, Ralf; Newrzela, Sebastian; Hartmann, Sylvia
    A novel immunohistochemical classifier to distinguish Hodgkin lymphoma from ALK anaplastic large cell lymphoma
    In: Modern Pathology Jg. 27 (2014) Nr. 10, S. 1345 - 1354
    ISSN: 1530-0285; 0893-3952
    Online Volltext: dx.doi.org/
  • Salaverria, I.; Martin-Guerrero, I.; Wagener, R.; Kreuz, M.; Kohler, C. W.; Richter, J.; Pienkowska-Grela, B.; Adam, Patrick; Burkhardt, B.; Claviez, A.; Damm-Welk, C.; Drexler, H. G.; Hummel, Michael; Jaffe, E. S.; Küppers, Ralf; Lefebvre, C.; Lisfeld, J.; Lof̈fler, M.; Macleod,~R.~A.~F.; Nagel, I.; Oschlies, I.; Rosolowski, M.; Russell, R. B.; Rymkiewicz, G.; Schindler, D.; Schlesner, M.; Scholtysik, Rene; Schwaenen, C.; Spang, R.; Szczepanowski, M.; Trum̈per, L.; Vater, I.; Wessendorf, S.; Klapper, W.; Siebert, Reiner
    A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma
    In: Blood Jg. 123 (2014) Nr. 8, S. 1187 - 1198
    ISSN: 1528-0020
    Online Volltext: dx.doi.org/
  • Aukema, S. M.; Kreuz, M.; Kohler, C. W.; Rosolowski, M.; Hasenclever, D.; Hummel, M.; Küppers, Ralf; Lenze, D.; Ott, G.; Pott, C.; Richter, J.; Rosenwald, A.; Szczepanowski, M.; Schwaenen, C.; Stein, H.; Trautmann, H.; Wessendorf, S.; Trümper, L.; Loeffler, M.; Spang, R.; Kluin, P. M.; Klapper, W.; Siebert, R.
    Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma
    In: Haematologica Jg. 99 (2014) Nr. 4, S. 726 - 735
    ISSN: 1592-8721
    Online Volltext: dx.doi.org/
  • Kulis, Marta; Heath, Simon; Castellano, Giancarlo; Beekman, Renee; Merkel, Angelika; Raineri, Emanuele; Esteve, Anna; Queiros, AnaC; Clot, Guillem; Schuyler, Ronald; Ecker, Simone; Pancaldi, Vera; Rico, Daniel; Agueda, Lidia; Blanc, Julie; Richardson, David; Clarke, Laura; Datta, Avik; Russinol, Nuria; Pascual, Marien; Aguirre, Xavier; Prosper, Felipe; Alignani, Diego; Caron, Gersende; Fest, Thierry; Muench, MarcusO; Fomin, Marina; Lee, Seung-Tae; Wiemels, JosephL; Valencia, Alfonso; Gut, Marta; Flicek, Paul; Stunnenberg, HendrikG; Siebert, Reiner; Küppers, Ralf; Gut, IvoG; Campo, Elias; Martin-Subero, JoseI
    Characterization of the DNA Methylome during Human B-Cell Differentiation
    In: Blood Jg. 124 (2014) Nr. 21, S. 4346
    ISSN: 0006-4971; 1528-0020
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  • Lopez, C.; Sungalee, S.; Bernhardt, SHStephanH; Schlesner, M.; Murga-Penas, E. M.; Haake, A.; Richter, J.; Ammerpohl, O.; Borkhardt, A.; Brors, B.; Burhardt, B.; Claviez, A.; Dreyling, M.; Ebert, S.; Eils, J.; Eils, R.; Haas, S.; Hansmann, M. L.; Hezaveh, K.; Hoell, J.; Hoffmann, S.; Hummel, M.; Karsch, D.; Klapper, W.; Kostezka, U.; Kreuz, M.; Kube, D.; Küppers, Ralf; Langenberger, D.; Lawerenz, C.; Leich, E.; Lenze, D.; Lichter, P.; Loeffler, M.; Moeller, P.; Radlwimmer, B.; Radomski, S.; Rohde, M.; Rosenstiel, P.; Rosenwald, A.; Rosolowski, M.; Schillhabel, M.; Schreiber, S.; Stadler, P. F.; Szczepanowski, M.; Truemper, L.; Weniger, Marc; Korbel, J.; Siebert, R.
    Comparison of conventional cytogenetic analysis and whole genome sequencing in germinal-center derived B-cell lymphomas in the framework of the ICGC MMML-SEQ project
    In: Haematologica Jg. 99 (2014) Nr. Suppl. 1, S. 407 - 408
    ISSN: 0390-6078; 1592-8721
  • Montesinos-Rongen, Manuel; Purschke, Frauke; Küppers, Ralf; Deckert, Martina
    Immunoglobulin repertoire of Primary lymphomas of the central nervous system
    In: Journal of Neuropathology & Experimental Neurology Jg. 73 (2014) Nr. 12, S. 1116 - 1125
    ISSN: 0022-3069; 1554-6578
    Online Volltext: dx.doi.org/
  • Tucci, Felicia A.; Bröring, Ruth; Lutterbeck, Melanie; Schlaak, Jörg Friedrich; Küppers, Ralf
    Intrahepatic B-cell follicles of chronically hepatitis C virus-infected individuals lack signs of an ectopic germinal center reaction
    In: European Journal of Immunology Jg. 44 (2014) Nr. 6, S. 1842 - 1850
    ISSN: 1521-4141
    Online Volltext: dx.doi.org/
  • Kreher, Stephan; Bouhlel, M Amine; Cauchy, Pierre; Lamprecht, Björn; Li, Shuang; Grau, Michael; Hummel, Franziska; Köchert, Karl; Anagnostopoulos, Ioannis; Jöhrens, Korinna; Hummel, Michael; Hiscott, John; Wenzel, Sören-Sebastian; Lenz, Peter; Schneider, Markus; Küppers, Ralf; Scheidereit, Claus; Giefing, Maciej; Siebert, Reiner; Rajewsky, Klaus; Lenz, Georg; Cockerill, Peter N; Janz, Martin; Dörken, Bernd; Bonifer, Constanze; Mathas, Stephan
    Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 111 (2014) Nr. 42, S. E4513 - E4522
    ISSN: 1091-6490; 0027-8424
    Online Volltext: dx.doi.org/
  • Küppers, Ralf; Dührsen, Ulrich; Hansmann, Martin-Leo
    Pathogenesis, diagnosis, and treatment of composite lymphomas
    In: The Lancet Oncology Jg. 15 (2014) Nr. 10, S. e435 - 46
    ISSN: 1470-2045; 1474-5488
    Online Volltext: dx.doi.org/
  • Bergmann, Anke K; Schneppenheim, Sina; Seifert, Marc; Betts, Matthew J; Haake, Andrea; Lopez, Cristina; Maria Murga Penas, Eva; Vater, Inga; Jayne, Sandrine; Dyer, Martin J S; Schrappe, Martin; Dührsen, Ulrich; Ammerpohl, Ole; Russell, Robert B; Küppers, Ralf; Dürig, Jan; Siebert, Reiner
    Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia
    In: Genes, Chromosomes and Cancer Jg. 53 (2014) Nr. 4, S. 309 - 316
    ISSN: 1045-2257; 1098-2264
    Online Volltext: dx.doi.org/
  • Tucci, Felicia; Küppers, Ralf
    Role of hepatitis C virus in B cell lymphoproliferations
    In: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 3 - 6
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Schmidt, A.; Küppers, Ralf
    Role of microRNAs in B cell leukemias and lymphomas
    In: Current Molecular Medicine Jg. 14 (2014) Nr. 5, S. 580 - 597
    ISSN: 1875-5666; 1566-5240
    Online Volltext: dx.doi.org/
  • Schneider, Stefanie; Crescenzi, Barbara; Schneider, Markus; Ascani, Stefano; Hartmann, Sylvia; Hansmann, Martin-Leo; Falini, Brunangelo; Mecucci, Cristina; Tiacci, Enrico; Küppers, Ralf
    Subclonal evolution of a classical Hodgkin lymphoma from a germinal center B-cell-derived mantle cell lymphoma
    In: International Journal of Cancer Jg. 134 (2014) Nr. 4, S. 832 - 843
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Schneider, Markus; Szaumkessel, Marcin; Richter, Julia; Ammerpohl, Ole; Hansmann, Martin-Leo; Küppers, Ralf; Siebert, Reiner; Giefing, Maciej
    The PRDX2 gene is transcriptionally silenced and de novo methylated in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
    In: Blood Jg. 123 (2014) Nr. 23, S. 3672 - 3674
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Tucci, Felicia Anna; Bröring, Ruth; Johansson, Patricia; Schlaak, Jörg Friedrich; Küppers, Ralf
    B Cells in Chronically Hepatitis C Virus-Infected Individuals Lack a Virus-Induced Mutation Signature in the TP53, CTNNB1, and BCL6 Genes
    In: Journal of Virology Jg. 87 (2013) Nr. 5, S. 2956 - 2962
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/
  • Giefing, Maciej; Winoto-Morbach, Supandi; Sosna, Justyna; Döring, Claudia; Klapper, Wolfram; Küppers, Ralf; Böttcher, Sebastian; Adam, Dieter; Siebert, Reiner; Schütze, Stefan
    Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma show alterations of genes encoding the NADPH oxidase complex and impaired reactive oxygen species synthesis capacity
    In: PLoS One Jg. 8 (2013) Nr. 12, S. e84928
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/
  • Rengstl, Benjamin; Newrzela, Sebastian; Heinrich, Tim; Weiser, Christian; Thalheimer, Frederic B.; Schmid, Frederike; Warner, Kathrin; Hartmann, Sylvia; Schroeder, Timm; Küppers, Ralf; Rieger, Michael A.; Hansmann, Martin-Leo
    Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 110 (2013) Nr. 51, S. 20729 - 20734
    ISSN: 1091-6490; 0027-8424
    Online Volltext: dx.doi.org/
  • Hartmann, S.; Tousseyn, T.; Döring, C.; Flüchter, P.; Hackstein, H.; Herreman, A.; Ponzoni, M.; De Wolf-Peeters, C.; Facchetti, F.; Gascoyne, R. D.; Küppers, Ralf
    Macrophages in T cell/histiocyte rich large B cell lymphoma strongly express metal-binding proteins and show a bi-activated phenotype
    In: International Journal of Cancer Jg. 133 (2013) Nr. 11, S. 2609 - 2618
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, R.; Seifert, Marc; Jäger, Ursula; Tschurtschenthaler, G.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 196
    ISSN: 0378-584X; 1423-0240
  • Hartmann, Sylvia; Döring, Claudia; Jakobus, Christina; Rengstl, Benjamin; Newrzela, Sebastian; Tousseyn, Thomas; Sagaert, Xavier; Ponzoni, Maurilio; Facchetti, Fabio; De Wolf-Peeters, Chris; Steidl, Christian; Gascoyne, Randy; Küppers, Ralf; Hansmann, Martin-Leo
    Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma : Endpoints of a spectrum of one disease?
    In: PLoS One Jg. 8 (2013) Nr. 11,
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/
  • Bohle, V.; Döring, C.; Hansmann, M.-L.; Küppers, Ralf
    Role of early B-cell factor 1 (EBF1) in Hodgkin lymphoma
    In: Leukemia Jg. 27 (2013) Nr. 3, S. 671 - 679
    ISSN: 1476-5551; 0887-6924
    Online Volltext: dx.doi.org/
  • Peveling-Oberhag, J.; Wolters, F.; Sellmann, Ludger; Lucioni, M.; Schubach, M.; Paulli, M.; Küppers, Ralf; Biskup, S.; Zeuzem, S.; Hansmann, M. L.
    Whole exome massive parallel sequencing of splenic marginal zone lymphoma reveals novel somatic mutations in NOTCH2 and SMYD1 genes
    In: European Journal of Cancer Jg. 49 (2013) Nr. Suppl. 2, S. 837
    ISSN: 0959-8049
  • Tiacci, Enrico; Döring, Claudia; Brune, Verena; Van Noesel, Carel J. M.; Klapper, Wolfram; Mechtersheimer, Gunhild; Falini, Brunangelo; Küppers, Ralf; Hansmann, Martin-Leo; Hansmann, M.-L.
    Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma
    In: Blood Jg. 120 (2012) Nr. 23, S. 4609 - 4620
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Ammerpohl, O; Haake, A; Pellissery, S; Giefing, M; Richter, J; Balint, B; Kulis, M; Le, J; Bibikova, M; Drexler, H G; Seifert, Marc; Shaknovic, R; Korn, B; Küppers, Ralf; Martín-Subero, J I; Siebert, R
    Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genes
    In: Leukemia Jg. 26 (2012) Nr. 1, S. 185 - 188
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Adams, David; Altucci, Lucia; Antonarakis, Stylianos E; Ballesteros, Juan; Beck, Stephan; Bird, Adrian; Bock, Christoph; Boehm, Bernhard; Campo, Elias; Caricasole, Andrea; Dahl, Fredrik; Dermitzakis, Emmanouil T; Enver, Tariq; Esteller, Manel; Estivill, Xavier; Ferguson-Smith, Anne; Fitzgibbon, Jude; Flicek, Paul; Giehl, Claudia; Graf, Thomas; Grosveld, Frank; Guigo, Roderic; Gut, Ivo; Helin, Kristian; Jarvius, Jonas; Küppers, Ralf; Lehrach, Hans; Lengauer, Thomas; Lernmark, Åke; Leslie, David; Loeffler, Markus; Macintyre, Elizabeth; Mai, Antonello; Martens, Joost H A; Minucci, Saverio; Ouwehand, Willem H; Pelicci, Pier Giuseppe; Pendeville, Hèléne; Porse, Bo; Rakyan, Vardhman; Reik, Wolf; Schrappe, Martin; Schübeler, Dirk; Seifert, Martin; Siebert, Reiner; Simmons, David; Soranzo, Nicole; Spicuglia, Salvatore; Stratton, Michael; Stunnenberg, Hendrik G; Tanay, Amos; Torrents, David; Valencia, Alfonso; Vellenga, Edo; Vingron, Martin; Walter, Jörn; Willcocks, Spike
    BLUEPRINT to decode the epigenetic signature written in blood
    In: Nature Biotechnology Jg. 30 (2012) Nr. 3, S. 224 - 226
    ISSN: 1087-0156; 1546-1696
    Online Volltext: dx.doi.org/
  • Seifert, Marc; Sellmann, Ludger; Bloehdorn, Johannes; Wein, Frederik; Stilgenbauer, Stephan; Dürig, Jan; Küppers, Ralf
    Cellular origin and pathophysiology of chronic lymphocytic leukemia
    In: Journal of Experimental Medicine (JEM) Jg. 209 (2012) Nr. 12, S. 2183 - 2198
    ISSN: 0022-1007; 1540-9538
    Online Volltext: dx.doi.org/
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Scholtysik, René; Seifert, Marc; Jäger, Ulrich; Tschurtschenthaler, Gertraud; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)
    In: Blood Jg. 120 (2012) Nr. 21, S. 3512
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Heuckmann, Johannes M.; Balke-Want, Hyatt; Malchers, Florian; Peifer, Martin; Sos, Martin L.; Koker, Mirjam; Meder, Lydia; Lovly, Christine M.; Heukamp, Lukas C.; Pao, William; Küppers, Ralf; Thomas, Roman K.
    Differential Protein Stability and ALK Inhibitor Sensitivity of EML4-ALK Fusion Variants
    In: Clinical Cancer Research Jg. 18 (2012) Nr. 17, S. 4682 - 4690
    ISSN: 1557-3265; 1078-0432
    Online Volltext: dx.doi.org/
  • Peveling-Oberhag, J.; Crisman, G.; Schmidt, A.; Döring, C.; Lucioni, M.; Arcaini, L.; Rattotti, S.; Hartmann, S.; Piiper, A.; Hofmann, W.-P.; Paulli, M.; Küppers, Ralf; Zeuzem, S.; Hansmann, M.-L.
    Dysregulation of global microRNA expression in splenic marginal zone lymphoma and influence of chronic hepatitis C virus infection
    In: Leukemia Jg. 26 (2012) Nr. 7, S. 1654 - 1662
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Otto, Claudia; Giefing, Maciej; Massow, Anne; Vater, Inga; Gesk, Stefan; Schlesner, Matthias; Richter, Julia; Klapper, Wolfram; Hansmann, Martin-Leo; Siebert, Reiner; Küppers, Ralf
    Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma
    In: British Journal of Haematology Jg. 157 (2012) Nr. 6, S. 702 - 708
    ISSN: 1365-2141; 0007-1048
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    New insights in the biology of Hodgkin lymphoma
    In: Hematology: The American Society of Hematology Education Program Book (2012) Nr. 1, S. 328 - 334
    ISSN: 1520-4383; 1520-4391
    Online Volltext: dx.doi.org/
  • Scholtysik, René; Nagel, Inga; Kreuz, Markus; Vater, Inga; Giefing, Maciej; Schwaenen, Carsten; Wessendorf, Swen; Trümper, Lorenz; Loeffler, Markus; Siebert, Reiner; Küppers, Ralf
    Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas
    In: International Journal of Cancer Jg. 131 (2012) Nr. 5, S. E830 - E835
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Richter, Julia; Schlesner, Matthias; Hoffmann, Steve; Kreuz, Markus; Leich, Ellen; Burkhardt, Birgit; Rosolowski, MacIej; Ammerpohl, Ole; Wagener, Rabea; Bernhart, Stephan H.; Lenze, Dido; Szczepanowski, Monika; Paulsen, Maren; Lipinski, Simone; Russell, Robert B.; Adam-Klages, Sabine; Apic, Gordana; Claviez, Alexander; Hasenclever, Dirk; Hovestadt, Volker; Hornig, Nadine; Korbel, Jan O.; Kube, Dieter; Langenberger, David; Lawerenz, Chris; Lisfeld, Jasmin; Meyer, Katharina; Picelli, Simone; Pischimarov, Jordan; Radlwimmer, Bernhard; Rausch, Tobias; Rohde, Marius; Schilhabel, Markus; Scholtysik, René; Spang, Rainer; Trautmann, Heiko; Zenz, Thorsten; Borkhardt, Arndt; Drexler, Hans G.; Möller, Peter; MacLeod, Roderick A. F.; Pott, Christiane; Schreiber, Stefan; Trümper, Lorenz; Loeffler, Markus; Stadler, Peter F.; Lichter, Peter; Eils, Roland; Küppers, Ralf; Hummel, Michael; Klapper, Wolfram; Rosenstiel, Philip; Rosenwald, Andreas; Brors, Benedikt; Siebert, Reiner
    Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
    In: Nature Genetics Jg. 44 (2012) Nr. 12, S. 1316 - 1320
    ISSN: 1061-4036; 1546-1718
    Online Volltext: dx.doi.org/
  • Küppers, Ralf; Dührsen, Ulrich
    Von Genchips, Antikörpern und leuchtenden Krebszellen : Translationale Forschung bei Lymphomen
    In: Unikate / Universität Duisburg-Essen: Berichte aus Forschung und Lehre (2012) Nr. 42: Translationale Krebsforschung: Auf dem Weg zu neuen Therapien, S. 70 - 79
    ISBN: 978-3-934359-42-0 ISSN: 0944-6060; 1869-3881
    Online Volltext: dx.doi.org/ Online Volltext
  • Sellmann, Ludger; Carpinteiro, Alexander; Nückel, Holger; Scholtysik, René; Siemer, Dörte; Klein-Hipass, Ludger; Kube, Dieter; Dürig, Jan; Dührsen, Ulrich; Stanelle, Jens; Küppers, Ralf
    p53 protein expression in chronic lymphocytic leukemia
    In: Leukemia and Lymphoma Jg. 53 (2012) Nr. 7, S. 1282 - 1288
    ISSN: 1042-8194; 1029-2403
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    CCR7 & lymphotoxin in lymphoma niche
    In: Blood Jg. 118 (2011) Nr. 4, S. 831 - 832
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Kordelas, L.; Gromke, Tanja; Steckel, Nina Kristin; Koldehoff, Michael; Beelen, Dietrich; Küppers, Ralf
    GCSF reduces mutated (CD27+) B-cells but increases unmutated naive (CD27-) B-cells in stem cell donors
    In: Bone Marrow Transplantation Jg. 46 (2011) Nr. Suppl. 1, S. S344 - S345
    ISSN: 0268-3369
  • Deckert, M.; Engert, A.; Brück, W.; Ferreri, A.J.M.; Finke, J.; Illerhaus, G.; Klapper, W.; Korfel, A.; Küppers, Ralf; Maarouf, M.; Montesinos-Rongen, M.; Paulus, W.; Schlegel, U.; Lassmann, H.; Wiestler, O.D.; Siebert, R.; Deangelis, L.M.
    Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma
    In: Leukemia Jg. 25 (2011) Nr. 12, S. 1797 - 1807
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Philipp, Claudia; Edelmann, Jennifer; Bühler, Andreas; Winkler, Dirk; Stilgenbauer, Stephan; Küppers, Ralf
    Mutation analysis of the TNFAIP3 (A20) tumor suppressor gene in CLL
    In: International Journal of Cancer Jg. 128 (2011) Nr. 7, S. 1747 - 1750
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    NPAT mutations in Hodgkin lymphoma
    In: Blood Jg. 118 (2011) Nr. 3, S. 484 - 485
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Sellmann, Ludger; Röth, Alexander; Baerlocher, Gabriela M.; Küppers, Ralf; Siemer, Dörte; Seifert, Marc; Dürig, Jan; Dührsen, Ulrich; Nückel, Holger; Opalka, Bertram; Bartels, Marius; de Beer, Dirk
    Telomeres and prognosis in patients with chronic lymphocytic leukaemia
    In: International Journal of Hematology Jg. 93 (2011) Nr. 1, S. 74 - 82
    ISSN: 1865-3774
    Online Volltext: dx.doi.org/
  • Salaverria, Itziar; Philipp, Claudia; Oschlies, Ilske; Kohler, Christian W.; Kreuz, Markus; Szczepanowski, Monika; Burkhardt, Birgit; Trautmann, Heiko; Gesk, Stefan; Andrusiewicz, Miroslaw; Berger, Hilmar; Fey, Miriam; Harder, Lana; Hasenclever, Dirk; Hummel, Michael; Loeffler, Markus; Mahn, Friederike; Martin-Guerrero, Idoia; Pellissery, Shoji; Pott, Christiane; Pfreundschuh, Michael; Reiter, Alfred; Richter, Julia; Rosolowski, Maciej; Schwaenen, Carsten; Stein, Harald; Trümper, Lorenz; Wessendorf, Swen; Spang, Rainer; Küppers, Ralf; Klapper, Wolfram; Siebert, Reiner
    Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults
    In: Blood Jg. 118 (2011) Nr. 1, S. 139 - 147
    ISSN: 0006-4971; 1528-0020
    Online Volltext: dx.doi.org/
  • Scholtysik, René; Kreuz, Markus; Klapper, Wolfram; Burkhardt, Birgit; Feller, Alfred C.; Hummel, Michael; Loeffler, Markus; Rosolowski, MacIej; Schwaenen, Carsten; Spang, Rainer; Stein, Harald; Thorns, Christoph; Trümper, Lorenz; Vater, Inga; Wessendorf, Swen; Zenz, Thorsten; Siebert, Reiner; Küppers, Ralf
    Detection of genomic aberrations in molecularly defined Burkitt’s lymphoma by array-based, high resolution, single nucleotide polymorphism analysis
    In: Haematologica Jg. 95 (2010) Nr. 12, S. 2047 - 2055
    ISSN: 1592-8721; 0390-6078
    Online Volltext: dx.doi.org/
  • Zenz, Thorsten; Mertens, Daniel; Küppers, Ralf; Döhner, Hartmut; Stilgenbauer, Stephan
    From pathogenesis to treatment of chronic lymphocytic leukaemia
    In: Nature Reviews Cancer Jg. 10 (2010) Nr. 1, S. 37 - 50
    ISSN: 1474-175X; 1474-1768
    Online Volltext: dx.doi.org/
  • Sellmann, Ludger; Scholtysik, Rene; Kreuz, Markus; Cyrull, Sandra; Tiacci, Enrico; Stanelle, Jens; Carpinteiro, Alexander; Nückel, Holger; Boes, Tanja; Gesk, Stefan; Siebert, Reiner; Klein-Hitpaß, Ludger; Dührsen, Ulrich; Dürig, Jan; Küppers, Ralf
    Gene dosage effects in chronic lymphocytic leukemia
    In: Cancer Genetics and Cytogenetics Jg. 203 (2010) Nr. 2, S. 149 - 160
    ISSN: 1873-4456; 0165-4608
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    Genomic imbalances in Hodgkin lymphoma
    In: Blood Jg. 116 (2010) Nr. 3, S. 309 - 311
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Hartmann, Sylvia; Gesk, Stefan; Scholtysik, René; Kreuz, Markus; Bug, Stefanie; Vater, Inga; Döring, Claudia; Cogliatti, Sergio; Parrens, Marie; Merlio, Jean-Philippe; Kwiecinska, Anna; Porwit, Anna; Piccaluga, Pier Paolo; Pileri, Stefano; Hoefler, Gerald; Küppers, Ralf; Siebert, Reiner; Hansmann, Martin-Leo
    High resolution SNP array genomic profiling of peripheral T cell lymphomas, not otherwise specified, identifies a subgroup with chromosomal aberrations affecting the REL locus
    In: British Journal of Haematology Jg. 148 (2010) Nr. 3, S. 402 - 412
    ISSN: 0007-1048; 1365-2141
    Online Volltext: dx.doi.org/
  • Stanelle, Jens; Döring, Claudia; Hansmann, Martin-Leo; Küppers, Ralf
    Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells
    In: Blood Jg. 116 (2010) Nr. 20, S. 4202 - 4211
    ISSN: 1528-0020; 0006-4971
    Online Volltext: dx.doi.org/
  • Müller, Claudia; Siemer, Dörte; Lehnerdt, Götz; Lang, Stephan; Küppers, Ralf
    Molecular analysis of IgD-positive human germinal centres
    In: International Immunology Jg. 22 (2010) Nr. 4, S. 289 - 298
    ISSN: 0953-8178; 1460-2377
    Online Volltext: dx.doi.org/
  • Schumacher, Martin A.; Schmitz, Roland; Brune, Verena; Tiacci, Enrico; Döring, Claudia; Hansmann, Martin-Leo; Siebert, Reiner; Küppers, Ralf; Hansmann, Martin-Leo
    Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin’s lymphoma
    In: Haematologica Jg. 95 (2010) Nr. 1, S. 153 - 157
    ISSN: 1592-8721
    Online Volltext: dx.doi.org/
  • Montesinos-Rongen, Manuel; Schmitz, Roland; Brunn, Anna; Gesk, Stefan; Richter, Julia; Hong, Ke; Wiestler, Otmar D.; Siebert, Reiner; Küppers, Ralf; Deckert, Martina
    Mutations of CARD11 but not TNFAIP3 may activate the NF-κB pathway in primary CNS lymphoma
    In: Acta Neuropathologica Jg. 120 (2010) Nr. 4, S. 529 - 535
    ISSN: 1432-0533; 0001-6322
    Online Volltext: dx.doi.org/
  • Schmidt, Annette; Schmitz, Roland; Giefing, Maciej; Martin-Subero, Jose Ignacio; Gesk, Stefan; Vater, Inga; Massow, Anne; Maggio, Ewerton; Schneider, Markus; Hansmann, Martin-Leo; Siebert, Reiner; Küppers, Ralf
    Rare occurrence of biallelic CYLD gene mutations in classical Hodgkin lymphoma
    In: Genes, Chromosomes and Cancer Jg. 49 (2010) Nr. 9, S. 803 - 809
    ISSN: 1045-2257; 1098-2264
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    Side population cells in Hodgkin lymphoma
    In: Leukemia and Lymphoma Jg. 51 (2010) Nr. 5, S. 741 - 742
    ISSN: 1042-8194; 1029-2403
    Online Volltext: dx.doi.org/
  • Nückel, Holger; Switala, Magdalena; Sellmann, Ludger; Horn, Peter; Dürig, Jan; Dührsen, Ulrich; Küppers, Ralf; Grosse-Wilde, Hans; Rebmann, Vera
    The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia
    In: Leukemia Jg. 24 (2010) Nr. 6, S. 1152 - 1159
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Brune, V.; Tiacci, E.; Pfeil, I.; Döring, C.; Eckerie, S.; van Noessel, Cl.; Klapper, W.; Falini, B.; von Heydebreck, A.; Metzler, D.; Bräuninger, A.; Hansmann, M.L.; Küppers, Ralf
    Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis
    In: Journal of Experimental Medicine (JEM) Jg. 10 (2008) Nr. 205, S. 2251 - 2268
    ISSN: 1540-9538; 0022-1007
    Online Volltext: dx.doi.org/
  • Sellmann, Ludger; Gesk, Stefan; Walter, Christoph; Ritgen, Matthias; Harder, Lana; Schroers, Roland; Siemer, Dörte; Nückel, Holger; Dührsen, Ulrich; Siebert, Reiner; Dürig, Jan; Küppers, Ralf
    Trisomy 19 is associated with trisomy 12 and mutated IGHV genes in B-chronic lymphocytic leukaemia
    In: British journal of haematology Jg. 138 (2007) Nr. 2, S. 217 - 220
    ISSN: 1365-2141; 0007-1048
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Nückel, Holger; Sellmann, Ludger; Siemer, Dörte; Küppers, Ralf; Siemer, Dörte; Küppers, Ralf; Dürig, Jan; Dührsen, Ulrich; Siffert, Winfried
    The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia
    In: Clinical cancer research Jg. 12 (2006) Nr. 19, S. 5686 - 5692
    ISSN: 1557-3265
    Online Volltext: dx.doi.org/

    • Vorworte / Nachworte

  • Küppers, Ralf
    Preface
    In: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.), (2019) S. v
    ISBN: 978-1-4939-9150-1; 978-1-4939-9151-8 ISSN: 1064-3745; 1940-6029

    • Rezensionen

  • Küppers, Ralf; Engert, Andreas; Hansmann, Martin-Leo
    Hodgkin lymphoma
    In: The Journal of Clinical Investigation (JCI) Jg. 122 (2012) Nr. 10, S. 3439 - 3447
    ISSN: 0021-9738; 1558-8238
    Online Volltext: dx.doi.org/

    • Abstracts

  • Lopez, Cristina; Wagener, Rabea; Kleinheinz, Kortine; Bausinger, Julia; Aukema, Sietse M.; Nagel, Inga; Toprak, Umut H.; Seufert, Julian; Altmueller, Janine; Thiele, Holger; Schneider, Christof; Kolarova, Julia; Park, Jeongbin; Hübschmann, Daniel; Penas, Eva M. Murga; Drexler, Hans G.; Attarbaschi, Andishe; Hovland, Randi; Kjeldsen, Eigil; Kneba, Michael; Kontny, Udo; de Leval, Laurence; Nürnberg, Peter; Oschlies, Ilske; Oscier, David; Schlegelberger, Brigitte; Stilgenbauer, Stephan; Wössmann, Wilhelm; Schlesner, Matthias; Burkhardt, Birgit; Klapper, Wolfram; Jaffe, Elaine S.; Küppers, Ralf; Siebert, Reiner;
    IG‐MYC ‐positive leukemia and lymphoma with precursor B‐cell phenotype are genetically and epigenetically distinct from Burkitt lymphomas
    Sixth International Symposium on Childhood, Adolescent and Young Adult Non‐Hodgkin Lymphoma Abstracts; 26‐29 September 2018; Rotterdam, Netherlands,
    In: British Journal of Haematology Jg. 182 (2018) Nr. Supplement 1, S. 19 - 20
    ISSN: 1365-2141; 0007-1048
    Online Volltext: dx.doi.org/
  • Deutsch, A.; Bergmann, T. C.; Fechter, K.; Prochazka, K.; Weniger, M. A.; Küppers, Ralf; Unterluggauer, J. J.; Greinix, H.; Beham-Schmid, C.; Neumeister, P.;
    Low NR4A1 expression is associated with an up-regulation of immune checkpoints and their ligands in DLBCL
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 82
    ISSN: 2296-5262; 2296-5270
    Online Volltext: dx.doi.org/
  • Pansy, K.; Fechter, K.; Unterluggauer, J. J.; Weniger, M. A.; Küppers, Ralf; Greinix, H.; Prochazka, K.; Karbiener, M.; Neumeister, P.; Deutsch, A.;
    Reduced NR4A1 levels are associated with high expression of miR-15a and miR-15a*in DLBCL
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 81
    ISSN: 2296-5262; 2296-5270
    Online Volltext: dx.doi.org/
  • Ossowski, J.; Keuneke, L.; Richter, J.; Dührsen, U.; Küppers, Ralf; Dürig, Jan; Johansson, Patricia; Murga Penas, E. M.; Bergmann, A. K.;
    The DNA-methylation status of BCL11B in T-Cell-Large Granular Lymphocytic Leukemia - a diagnostic target
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 317
    ISSN: 2296-5262; 2296-5270
    Online Volltext: dx.doi.org/
  • Unterluggauer, J. J.; Prochazka, K.; Tomazic, P. V.; Huber, H. J.; Seeboeck, R.; Fechter, K.; Steinbauer, E.; Gruber, V.; Feichtinger, J.; Pichler, M.; Weniger, M. A.; Küppers, Ralf; Sill, H.; Schicho, R.; Neumeister, P.; Beham-Schmid, C.; Deutsch, A.; Haybaeck, J.;
    Translation initiation factors are over-expressed in aggressive lymphomas and influence their clinical course
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 164
    ISSN: 2296-5262; 2296-5270
    Online Volltext: dx.doi.org/
  • Tiacci, E.; Weniger, Marc; Schneider, S.; Arnolds, Judith; Ruschenbaum, S.; Duppach, J.; Seifert, M.; Doring, C.; Hansmann, M. L.; Küppers, Ralf
    CD30+ Germinal Center (GC) B cells are transciptionally related to light zone GC B cells reentering the dark zone, and to tumor cells of Classical Hodkin Lymphoma (CHL)
    In: Haematologica Jg. 102 (2017) Nr. Suppl. 3, S. 30
    ISSN: 0390-6078; 1592-8721
  • Johansson, Patricia; Pancaldi, V.; Castellano, G.; Oschlies, I.; Queiros, A.; Iaccarino, I.; Valencia, A.; Martin-Subero, J. I.; Penas, EMM; Ammerpohl, O.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan; Siebert, R.; Pau, ECD; Bergmann, A. K.
    Epigenetic analyses of T-cell large granular lymphocytic leukemia identify differentially methylated enhancer regions leading to deregulation of gene interactions
    In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 109 - 110
    ISSN: 2296-5270
    Online Volltext: dx.doi.org/
  • Schreiber, Fedor; Kahnert, S.; Goehlich, A.; Greifendorf, D.; Bartels, F.; Janzyk, U.; Lennartz, K.; Kirstein, Uwe; Rennings, Andreas; Küppers, Ralf; Erni, Daniel
    Efficient chip architectures for a microfluidic cell sorter actuated by electrowetting and its electro-hydrodynamic analysis
    In: 1st YRA MedTech Symposium 2016: April 8th / 2016 / University of Duisburg-Essen / 1st YRA MedTech Symposium (YRA-MedTech 2016), April 8th 2016 University of Duisburg-Essen, Duisburg, Germany / Erni, Daniel; (Hrsg.), (2016) S. 31 - 32
    ISBN: 978-3-940402-06-6
    Online Volltext
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Bergmann, A.; Siebert, R.; Scholtysik, R.; Przekopowitz, M.; Seifert, M.; Zenz, T.; Dührsen, Ulrich; Küppers, Ralf; Dürig, Jan
    Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3: Jahrestagung der ­Deutschen, Österreichischen und ­Schweizerischen ­Gesellschaften für Hämatologie und ­Medizinische Onkologie, Leipzig, 14.–18. Oktober 2016: Abstracts, S. 238 - 238
    ISSN: 2296-5270
    Online Volltext: dx.doi.org/
  • Lollies, A.; Hartmann, S.; Schneider, M.; Bracht, T.; Arnolds, Judith; Klein-Hitpaß, Ludger; Sitek, B.; Hansmann, M. L.; Küppers, Ralf; Weniger, Marc
    The AP-1 transcription factor BATF3 regulates MYC expression and is required for tumor cell survival in classical Hodgkin lymphoma and anaplastic large cell lymphoma
    In: Haematologica Jg. 101 (2016) Nr. S 5: You have access 10th International Symposium on Hodgkin Lymphoma, Cologne, Germany, October 22–25, 2016, Abstract Book, S. 2
    ISSN: 0390-6078; 1592-8721
  • Küppers, Ralf;
    Cellular origin of CLL
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,
    In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 109
    ISSN: 2296-5270; 2296-5262
    Online Volltext: dx.doi.org/
  • Thurner, L.; Hartmann, S.; Kemele, M.; Regitz, E.; Fadle, N.; Preuss, K. D.; Bohle, R. M.; Vomanen, M.; Kempf, V. A. J.; Von, M. L.; Küppers, Ralf; Hansmann, M. L.; Pfreundschuh, M.;
    Moraxella catarrhalis - the infectious origin of nodular lymphocyte predominant Hodgkin lymphoma of IgD type?
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,
    In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 211
    ISSN: 2296-5270
    Online Volltext: dx.doi.org/
  • Küppers, Ralf;
    Aspects of Hodgkin lymphoma pathogenesis
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,
    In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 115
    ISSN: 2296-5262
    Online Volltext: dx.doi.org/
  • Thurner, L.; Hartmann, S.; Kemele, M.; Fadle, N.; Regitz, E.; Schneider, N.; Kim, Y-J; Preuss, K. D.; Bohle, R. M.; Küppers, Ralf; Hansmann, M. L.; Pfreundschuh, M.;
    Autoreactivity of B cell receptors of nodular lymphocyte predominant Hodgkin lymphoma
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,
    In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 74 - 75
    ISSN: 2296-5262
    Online Volltext: dx.doi.org/
  • Seifert, Marc; Przekopowitz, Martina; Schweigle, Stefanie; Budeus, Bettina; Taudien, Sarah; Lollies, Anna; Ronge, Viola; Sellmann, Ludger; Hillen, Uwe; Engler, Harald; Schedlowski, Manfred; Singer, Bernhard B.; Hoffmann, Daniel; Küppers, Ralf
    Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B Cells
    In: Scandinavian Journal of Immunology Jg. 80 (2014) Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233
    ISSN: 0300-9475; 1365-3083
    Online Volltext: dx.doi.org/
  • Peveling-Oberhag, Jan; Crisman, G.; Schmidt, A.; Döring, C.; Lucioni, M.; Arcaini, L.; Hartmann, S.; Piiper, A.; Hofmann, W. P.; Paulli, M.; Küppers, Ralf; Zeuzem, S.; Hansmann, M. L.
    Dysregulation of micro-RNA expression in splenic marginal zone lymphoma in patients with and without chronic hepatitis C virus infection
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 / Jg. 54 (2011) Nr. Suppl. 1, S. S324 - S325
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/

    • Beiträge in Sammelwerken und Tagungsbänden

  • Küppers, Ralf; Schneider, Markus; Hansmann, Martin-Leo
    Laser-Based Microdissection of Single Cells from Tissue Sections and PCR Analysis of Rearranged Immunoglobulin Genes from Isolated Normal and Malignant Human B Cells
    In: Lymphoma: Methods and Protocols 2019, S. 61 - 75
    ISBN: 978-1-4939-9150-1; 978-1-4939-9151-8
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    Origin of Hodgkin Lymphoma
    In: Hematology: Basic Principles and Practice / Hoffmann, Ronald; Silberstein, Leslie E. (Hrsg.), 2018, S. 1204 - 1211
    ISBN: 9781455740413; 9780323357623
    Online Volltext: dx.doi.org/
  • Seifert, Marc; Küppers, Ralf
    Determining the Origin of Human Germinal Center B Cell-Derived Malignancies
    In: Germinal Centers: Methods and Protocols / Calado, Dinis Pedro (Hrsg.), 2017, S. 253 - 279
    ISBN: 978-1-4939-7094-0; 978-1-4939-7095-7
    Online Volltext: dx.doi.org/
  • Kahnert, Stefan; Schreiber, Fedor; Goehlich, Andreas; Greifendorf, Dieter; Lennartz, Klaus; Kirstein, Uwe; Bartels, Frank; Janzyk, Udo; Rennings, Andreas; Erni, Daniel; Küppers, Ralf; Vogt, Holger
    Digital microfluidics for microchip-based cell sorting
    In: Mikro-Nano-Integration: Beiträge des 6. GMM-Workshops, 5.-6. Oktober 2016 in Duisburg / GMM-Workshop Mikro-Nano-Integration ; 6 (Duisburg) : 2016.10.05-06 / 2016, S. 17 - 21
    ISBN: 978-3-8007-4278-3
  • Kahnert, Stefan; Schreiber, Fedor; Erni, Daniel; Greifendorf, Dieter; Lennartz, Klaus; Kirstein, Uwe; Bartels, Frank; Janzyk, Udo; Rennings, Andreas; Küppers, Ralf; Vogt, Holger
    Entwicklung einer Mikrochip navigierten Zellsortieranlage
    In: MEMS, Mikroelemente, Systeme / MikroSystemTechnik Kongress 2015 ; 26. - 28. Oktober 2015 in Karlsruhe / 2015, S. 463 - 466
    ISBN: 978-3-8007-4100-7
    Online Volltext
  • Rosenwald, Andreas; Küppers, Ralf
    Pathology and Molecular Pathology of Hodgkin Lymphoma
    In: Hodgkin Lymphoma: A Comprehensive Overview / Engert, Andreas; Younes, Anas (Hrsg.), 2015, S. 45 - 64
    ISBN: 978-3-319-12504-6; 978-3-319-12505-3
    Online Volltext: dx.doi.org/
  • Küppers, Ralf; Schneider, Markus; Hansmann, Martin-Leo
    Laser-based microdissection of single cells from tissue sections and PCR analysis of rearranged immunoglobulin genes from isolated normal and malignant human B cells
    In: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.), 2013, S. 49 - 63
    ISBN: 978-1-62703-268-1; 978-1-62703-269-8 ISSN: 1940-6029
    Online Volltext: dx.doi.org/
  • Seifert, Marc; Scholtysik, René; Küppers, Ralf
    Origin and Pathogenesis of B Cell Lymphomas
    In: Lymphoma: Methods and Protocols 2013, S. 1 - 25
    ISBN: 978-1-62703-268-1; 978-1-62703-269-8 ISSN: 1064-3745
    Online Volltext: dx.doi.org/
  • Hansmann, Martin-Leo; Hartmann, Sylvia; Küppers, Ralf
    Hodgkin lymphoma
    In: The Lymphoid Neoplasms 3ed 2010, S. 587 - 607
    ISBN: 9781444113228; 9780340809471
    Online Volltext: dx.doi.org/
  • Küppers, Ralf
    Overview of the immune system
    In: The Lymphoid Neoplasms 3ed 2010, S. 143 - 155
    ISBN: 9781444113228; 9780340809471
    Online Volltext: dx.doi.org/
  • Küppers, Ralf; Tiacci, Enrico
    Tumors, Malignant / Lymphoma
    In: Encyclopedia of Respiratory Medicine / Laurent, Geoffrey J.; Shapiro, Steven D. (Hrsg.), 2006, S. 344 - 350
    ISBN: 978-0-12-370879-3
    Online Volltext: dx.doi.org/

    • Bücher/Sammelwerke/Tagungsbände

  • Küppers, Ralf
    Lymphoma : Methods and Protocols
    New York, NY (2019) XII, 439 p. 66 illus., 48 illus. in color
    (Methods in Molecular Biology ; 1956)
    ISBN: 978-1-4939-9151-8; 978-1-4939-9150-1
    Online Volltext: dx.doi.org/

    • Poster / Posterbeiträge

  • Schreiber, Fedor; Kahnert, Stefan; Goehlich, Andreas; Greifendorf, Dieter; Bartels, Frank; Michelsen, Ulrike; Lennartz, Klaus; Kirstein, Uwe; Rennings, Andreas; Küppers, Ralf; Erni, Daniel;
    An efficient on-chip electrowetting cell sorter architecture based on smart diffusion
    Microfluidics 2014 - EMBL Conference, 23 - 25.07.2014, Heidelberg,
    (2014)
    Online Volltext