Personensuche
Personensuche
Es wurde 1 Person gefunden.
Aktuelle Veranstaltungen
Keine aktuellen Veranstaltungen.
Vergangene Veranstaltungen (max. 10)
Keine vergangenen Veranstaltungen.
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
Correction: Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastomaIn: Oncogene, Jg. 42, 2023, Nr. 2, S. 168DOI (Open Access)
-
Multimodal Therapy with Consolidating Haploidentical Stem Cell Transplantation and Dinutuximab Beta for Patients with High-Risk Neuroblastoma and Central Nervous System RelapseIn: Journal of Clinical Medicine (JCM), Jg. 12, 2023, Nr. 19, 6196DOI (Open Access)
-
Profile of the multicenter cohort of the German Cancer Consortium’s Clinical Communication PlatformIn: European Journal of Epidemiology, Jg. 38, 2023, Nr. 5, S. 573 – 586DOI (Open Access)
-
Comparing efficacy and side effects of two systemic chemotherapy regimens for eye-preserving therapy in children with retinoblastomaIn: Pediatric Blood and Cancer, Jg. 69, 2022, Nr. 2, e29362DOI (Open Access)
-
Adjuvant therapy of histopathological risk factors of retinoblastoma in Europe : A survey by the European Retinoblastoma Group (EURbG)In: Pediatric Blood and Cancer, Jg. 68, 2021, Nr. 6, e28963DOI (Open Access)
-
Eye tumors in childhood as first sign of tumor predisposition syndromes : Insights from an observational study conducted in Germany and AustriaIn: Cancers, Jg. 13, 2021, Nr. 8, S. 1876DOI, Online Volltext (Open Access)
-
Long-term follow-up of children with neuroblastoma receiving radiotherapy to metastatic lesions within the German Neuroblastoma Trials NB97 and NB 2004In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics, Jg. 197, 2021, Nr. 8, S. 683 – 689DOI (Open Access)
-
Proton Beam Therapy for Children With Neuroblastoma : Experiences From the Prospective KiProReg RegistryIn: Frontiers in Oncology, Jg. 10, 2021, S. 617506DOI, Online Volltext (Open Access)
-
Extended induction chemotherapy does not improve the outcome for high-risk neuroblastoma patients : results of the randomized open-label GPOH trial NB2004-HRIn: Annals of Oncology, Jg. 31, 2020, Nr. 3, S. 422 – 429DOI (Open Access)
-
Genotyping circulating tumor DNA of pediatric Hodgkin lymphomaIn: Leukemia, Jg. 34, 2020, Nr. 1, S. 151 – 166
-
Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups : a report of the Cooperative Weichteilsarkom Studiengruppe (CWS)In: Journal of Cancer Research and Clinical Oncology, 2020
-
Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4⁺ CAR T Cell EfficacyIn: Frontiers in Immunology, Jg. 11, 2020, S. 531DOI (Open Access)
-
German Cancer Consortium (DKTK) : A national consortium for translational cancer researchIn: Molecular Oncology, Jg. 13, 2019, Nr. 3, S. 535 – 542DOI (Open Access)
-
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastomaIn: Cancer Letters, Jg. 455, 2019, S. 24 – 33
-
A mechanistic classification of clinical phenotypes in neuroblastomaIn: Science, Jg. 362, 2018, Nr. 6419, S. 1165 – 1170DOI, Online Volltext (Open Access)
-
Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia : results from a phase III trialIn: Leukemia, Jg. 32, 2018, S. 1657 – 1669
-
High-dose chemotherapy and blood autologous stem-cell rescue compared with standard chemotherapy in localized high-risk ewing sarcoma : Results of Euro-E.W.I.N.G.99 and Ewing-2008In: Journal of Clinical Oncology (JCO), Jg. 36, 2018, Nr. 31, S. 3110 – 3119DOI, Online Volltext (Open Access)
-
The landscape of genomic alterations across childhood cancersIn: Nature, Jg. 555, 2018, Nr. 7696, S. 321 – 327DOI (Open Access)
-
2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic TumorsIn: Klinische Pädiatrie, Jg. 229, 2017, Nr. 3, S. 147 – 167
-
Accelerating drug development for neuroblastoma - New Drug Development Strategy : an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma projectIn: Expert Opinion on Drug Discovery, Jg. 12, 2017, Nr. 8, S. 801 – 811DOI, Online Volltext (Open Access)
-
Childhood cancer predisposition syndromes : A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and HematologyIn: American Journal of Medical Genetics, Part A, Jg. 173, 2017, Nr. 4, S. 1017 – 1037
-
Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors : a report from the German reference centerIn: Pediatric Blood and Cancer, Jg. 64, 2017, Nr. 1, S. 71 – 80
-
Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell linesIn: Clinical & Experimental Ophthalmology, Jg. 45, 2017, Nr. 3, S. 288 – 296
-
RITA displays anti-tumor activity in medulloblastomas independent of TP53 statusIn: OncoTarget, Jg. 8, 2017, Nr. 17, S. 27882 – 27891DOI (Open Access)
-
Targeting tachykinin receptors in neuroblastomaIn: OncoTarget, Jg. 8, 2017, Nr. 1, S. 430 – 443DOI (Open Access)
-
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma modelsIn: OncoTarget, Jg. 8, 2017, Nr. 4, S. 6730 – 6741DOI (Open Access)
-
Embryonale Bauchtumoren im Kindes- und JugendalterIn: Der Onkologe, Jg. 22, 2016, Nr. 12, S. 940 – 953
-
How Eye-Preserving Therapy Affects Long-Term Overall Survival in Heritable Retinoblastoma SurvivorsIn: Journal of Clinical Oncology (JCO), Jg. 34, 2016, Nr. 26, S. 3183 – 3188
-
Identification and Tumour-Binding Properties of a Peptide with High Affinity to the Disialoganglioside GD2In: PLoS ONE, Jg. 11, 2016, Nr. 10, S. e0163648DOI, Online Volltext (Open Access)
-
MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastomaIn: OncoTarget, Jg. 7, 2016, S. 66344 – 66359DOI (Open Access)
-
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot studyIn: European Journal of Cancer (EJC), Jg. 65, 2016, S. 91 – 101
-
Pädiatrische Onkologie : Behandlungsstrukturen und aktuelle HerausforderungenIn: Der Onkologe, Jg. 22, 2016, Nr. 12, S. 904 – 907
-
Targeting MYCN-driven transcription by BET-bromodomain inhibitionIn: Clinical Cancer Research, Jg. 22, 2016, Nr. 10, S. 2470 – 2781DOI (Open Access)
-
The mitochondrial genetic landscape in neuroblastoma from tumor initiation to relapseIn: OncoTarget, Jg. 7, 2016, Nr. 6, S. 6620 – 6625DOI (Open Access)
-
Absence of telomerase reverse transcriptase promoter mutations in neuroblastomaIn: Biomedical Reports, Jg. 3, 2015, Nr. 4, S. 443 – 446
-
MiR-34a deficiency accelerates medulloblastoma formation in vivoIn: International Journal of Cancer, Jg. 136, 2015, Nr. 10, S. 2293 – 2303DOI (Open Access)
-
Mutational dynamics between primary and relapse neuroblastomasIn: Nature Genetics, Jg. 47, 2015, Nr. 8, S. 872 – 877
-
Neoadjuvant/adjuvant treatment of high-risk retinoblastoma : a report from the German Retinoblastoma Referral CentreIn: British Journal of Ophthalmology (BJO), Jg. 99, 2015, Nr. 7, S. 949 – 953
-
Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumorsIn: OncoTarget, Jg. 6, 2015, Nr. 17, S. 15425 – 15435DOI (Open Access)
-
Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in miceIn: Cancer Immunology, Immunotherapy, Jg. 64, 2015, Nr. 10, S. 1215 – 1227
-
Targeting super-enhancer induced gene expression with the novel BRD4 inhibitor OTX015 in preclinical models of MYCN-amplified neuroblastomaIn: Cancer Research, Jg. 75, 2015, Nr. 15 Suppl., S. 4731
-
Telomerase activation by genomic rearrangements in high-risk neuroblastomaIn: Nature, Jg. 526, 2015, Nr. 7575, S. 700 – 704DOI, Online Volltext (Open Access)
-
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiationIn: Science Signaling, Jg. 8, 2015, Nr. 374
-
miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating SurvivinIn: International Journal of Cancer, Jg. 136, 2015, Nr. 6, S. 1308 – 1320DOI (Open Access)
-
BET protein inhibitor OTX015 has selective anti-tumoral activity in preclinical models of MYCN- amplified neuroblastomaIn: Cancer Research, Jg. 74, 2014, Nr. 19 Suppl., S. 3967
-
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patientsIn: PLoS ONE, Jg. 9, 2014, Nr. 12, S. e114696DOI (Open Access)
-
Impairment of Bone Health in Pediatric Patients with Hemolytic AnemiaIn: PLoS ONE, Jg. 9, 2014, Nr. 10, S. e108400DOI (Open Access)
-
Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastomaIn: Pediatric Blood and Cancer, Jg. 61, 2014, Nr. 10, S. 1867 – 1870
-
Neuroblastoma in dialog with its stroma : NTRK1 is a regulator of cellular cross-talk with Schwann cellsIn: OncoTarget, Jg. 5, 2014, Nr. 22, S. 11180 – 11192DOI (Open Access)
-
BET bromodomain protein inhibition is a therapeutic option for medulloblastomaIn: OncoTarget, Jg. 4, 2013, Nr. 11, S. 2080 – 2095
-
Chemoreduction improves eye retention in patients with retinoblastoma : a report from the German Retinoblastoma Reference CentreIn: British Journal of Ophthalmology (BJO), Jg. 97, 2013, Nr. 10, S. 1277 – 1283
-
Diagnose und Behandlung des Retinoblastoms: aktuelle Konzepte zur sicheren Tumorkontrolle bei Erhalt des SehvermögensIn: Klinische Monatsblätter für Augenheilkunde, Jg. 230, 2013, Nr. 3, S. 232 – 242
-
Discovery of a new bioactive molecule for neuroblastomaIn: Chemical Biology and Drug Design, Jg. 82, 2013, Nr. 2, S. 233 – 241
-
Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cellsIn: International Journal of Cancer, Jg. 133, 2013, Nr. 4, S. 908 – 919
-
Focal DNA copy number changes in neuroblastoma target MYCN regulated genesIn: PLoS ONE, Jg. 8, 2013, Nr. 1, S. e52321DOI (Open Access)
-
Fortschritte bei jungen KrebspatientInnen : Personalisierte Diagnostik und Behandlung für krebskranke KinderIn: Unikate: Berichte aus Forschung und Lehre, 2013, Nr. 44: Medizin: 50 Jahre Universitätsklinikum Essen, S. 126 – 134DOI, Online Volltext (Open Access)
-
Grußwort der Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH)In: Klinische Pädiatrie, Jg. 225, 2013, Nr. Suppl. 1, S. 7
-
Knock-down of lysine specific demethylase-1 drives hematopoietic stem cells into a CD41+myeloid biased phenotypeIn: Onkologie, Jg. 36, 2013, Nr. Suppl. 7, S. 228 – 228
-
LIN28B drives neuroblastoma oncogenesis through let7-MYCN signalingIn: Cancer Research, Jg. 73, 2013, Nr. 8 Suppl. 1, S. 4596
-
Logic Learning Machine creates explicit and stable rules stratifying neuroblastoma patientsIn: BMC Bioinformatics, Jg. 14, 2013, Nr. Suppl. 7, S. S12DOI (Open Access)
-
Long-term follow-up of pediatric patients receiving total body irradiation before hematopoietic stem cell transplantation and post-transplant survival of >2 yearsIn: Pediatric Blood and Cancer, Jg. 60, 2013, Nr. 11, S. 1792 – 1797
-
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cellsIn: Oncogene, Jg. 32, 2013, Nr. 8, S. 1059 – 1065
-
MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1AIn: International Journal of Cancer, Jg. 133, 2013, Nr. 5, S. 1064 – 1073
-
Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAsIn: Oncogene, Jg. 32, 2013, Nr. 24, S. 2927 – 2936
-
Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interactionIn: Scientific Reports, Jg. 3, 2013, S. 1351DOI (Open Access)
-
Next-generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN-amplified neuroblastomaIn: International Journal of Cancer, Jg. 132, 2013, Nr. 3, S. E106 – E115
-
Paraneoplastic hypercalcemia associated with juvenile granulosa cell tumorIn: Klinische Pädiatrie, Jg. 225, 2013, Nr. 3, S. 170 – 171
-
Targeted Therapy for Neuroblastoma : ALK InhibitorsIn: Klinische Pädiatrie, Jg. 225, 2013, Nr. 6, S. 303 – 308
-
The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemiaIn: BMC Cancer, Jg. 13, 2013, S. 452DOI (Open Access)
-
The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastomaIn: Acta Neuropathologica Communications, Jg. 1, 2013, Nr. 1, S. 19DOI (Open Access)
-
Update zur personalisierten Diagnostik und Behandlung krebskranker KinderIn: Klinische Pädiatrie, Jg. 225, 2013, Nr. 3, S. 107 – 109
-
Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumorsIn: Genes, Chromosomes and Cancer, Jg. 52, 2013, Nr. 10, S. 983 – 985
-
Current Concepts for Diagnosis and Treatment of Retinoblastoma in Germany : Aiming for Safe Tumor Control and Vision PreservationIn: Klinische Pädiatrie, Jg. 224, 2012, Nr. 6, S. 339 – 347
-
Die Behandlungssituation in der pädiatrischen Onkologie und Hämatologie nach der Änderung des Arzneimittelgesetzes im Jahr 2004 und die Prüfung neuer TherapieoptionenIn: Klinische Pädiatrie, Jg. 224, 2012, Nr. 6, S. 335 – 338
-
EditorialIn: Unikate: Berichte aus Forschung und Lehre, 2012, Nr. 42: Translationale Krebsforschung : Auf dem Weg zu neuen Therapien, S. 6 – 7DOI, Online Volltext (Open Access)
-
Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcomeIn: British Journal of Cancer (BJC), Jg. 107, 2012, Nr. 8, S. 1409 – 1417DOI (Open Access)
-
Genen auf der Spur : wie genomweite Analysen am Modell Neuroblastom zukünftige Therapiemöglichkeiten aufzeigenIn: Unikate: Berichte aus Forschung und Lehre, 2012, Nr. 42: Translationale Krebsforschung: Auf dem Weg zu neuen Therapien, S. 22 – 31DOI, Online Volltext (Open Access)
-
Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomasIn: International Journal of Cancer, Jg. 130, 2012, Nr. 11, S. 2599 – 2606
-
LIN28B drives neuroblastoma oncogenesis through let7-MYCN signalingIn: Klinische Pädiatrie, Jg. 224, 2012, S. 222
-
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppressionIn: Nature Genetics, Jg. 44, 2012, Nr. 11, S. 1199 – 1206
-
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiationIn: Leukemia, Jg. 26, 2012, Nr. 9, S. 2039 – 2051
-
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastomaIn: Oncogene, Jg. 31, 2012, Nr. 12, S. 1571 – 1581
-
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomasIn: Neuro-Oncology, Jg. 14, 2012, Nr. 7, S. 859 – 869DOI (Open Access)
-
RITA-p53 activation in medulloblastoma as a new approach for treatment?In: Klinische Pädiatrie, Jg. 224, 2012, S. 221
-
Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosisIn: Cancer Research, Jg. 72, 2012, Nr. 10, S. 2645 – 2656DOI (Open Access)
-
Targeted expression of mutated ALK induces neuroblastoma in transgenic miceIn: Science Translational Medicine, Jg. 4, 2012, Nr. 141, S. 141ra91
-
The JARID 1C histone demethylase is upregulated in aggressive neuroblastomas independent of MYCN amplificationIn: Klinische Pädiatrie, Jg. 224, 2012, S. 221 – 222
-
The first European interdisciplinary ewing sarcoma research summitIn: Frontiers in Oncology, Jg. 2, 2012, S. 54DOI (Open Access)
-
The mentoring of women for medical career developmentIn: International Journal of Mentoring and Coaching in Education, Jg. 1, 2012, Nr. 2, S. 155 – 168
-
The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastomaIn: Cell Cycle, Jg. 11, 2012, Nr. 3, S. 569 – 581
-
Total body irradiation (TBI) in the conditioning regimens prior to hematopoietic stem cell transplantation (HSCT) : Long-term follow-up of 98 pediatric patientsIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics, Jg. 188, 2012, Nr. Suppl. 1, S. 108
-
Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastomaIn: Oncogene, Jg. 30, 2011, Nr. 25, S. 2823 – 2835
-
Detection of neuroblastoma cells during clinical follow up : advanced flow cytometry and rt-PCR for tyrosine hydroxylase using both conventional and real-time PCRIn: Klinische Pädiatrie, Jg. 223, 2011, Nr. 6, S. 326 – 331
-
High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary NeuroblastomaIn: Clinical Cancer Research, Jg. 17, 2011, Nr. 15, S. 5082 – 5092
-
Neue Entwicklungen zur Genetik und Therapie des RetinoblastomsIn: Klinische Monatsblätter für Augenheilkunde, Jg. 228, 2011, Nr. 7, S. 593 – 598
-
Neuroblastoma develops from neural crest stem cellsIn: Klinische Pädiatrie, Jg. 223, 2011, Nr. 3, S. 198 – 198
-
Pharmacological activation of the p53 pathway by nutlin-3 inhibits medulloblastoma cell proliferation in vitro and in vivoIn: European Journal of Pediatrics, Jg. 170, 2011, Nr. 2, S. 267 – 268
-
Polo-like kinase 1 is a therapeutic target in high-risk neuroblastomaIn: Clinical Cancer Research, Jg. 17, 2011, Nr. 4, S. 731 – 741
-
Progress in treatment and risk stratification of neuroblastoma : impact on future clinical and basic researchIn: Seminars in Cancer Biology, Jg. 21, 2011, Nr. 4, S. 217 – 228
-
Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinomaIn: International Journal of Cancer, Jg. 129, 2011, Nr. 10, S. 2390 – 2399
-
Viscum Album (mistletoe) extract inhibits growth of pediatric tumor cells in vitroIn: Klinische Pädiatrie, Jg. 223, 2011, Nr. 3, S. 198
-
miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samplesIn: Clinical Cancer Research, Jg. 17, 2011, Nr. 24, S. 7684 – 7692
-
Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signatureIn: Clinical Cancer Research, Jg. 16, 2010, Nr. 5, S. 1532 – 1541
-
Accurate prediction of neuroblastoma outcome based on miRNA expression profilesIn: International Journal of Cancer, Jg. 127, 2010, Nr. 10, S. 2374 – 2385
-
Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastomaIn: Clinical Cancer Research, Jg. 16, 2010, Nr. 11, S. 2971 – 2978
-
Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastomaIn: Nucleic Acids Research, Jg. 38, 2010, Nr. 17, S. 5919 – 5928
-
IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusionIn: Journal of Immunotherapy, Jg. 33, 2010, Nr. 2, S. 200 – 210
-
KDM 1A/LSD1 has a functional role in migration of medulloblastoma cells and their neuronal precursorsIn: Klinische Pädiatrie, Jg. 222, 2010, Nr. 3, S. 221
-
LSD1 is a novel therapeutic target in neuroblastoma (NB) and medulloblastoma (MB)In: European Journal of Pediatrics, Jg. 169, 2010, Nr. 3, S. 381
-
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumorsIn: Oncogene, Jg. 29, 2010, Nr. 9, S. 1394 – 1404
-
Meningitis durch Streptococcus equi
36. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin und 18. Jahrestagung der Gesellschaft für Pädiatrische Infektiologie gemeinsam mit Société Luxembourgoise de Pédiatrie Saarbrücken, 17.–19. Juni 2010,In: Klinische Pädiatrie, Jg. 222, 2010, Nr. Suppl. 1, S. S51 -
Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplificationIn: Clinical Cancer Research, Jg. 16, 2010, Nr. 17, S. 4353 – 4362
-
Neuroblastoma : biology, prognosis, and treatmentIn: Hematology/Oncology Clinics of North America, Jg. 24, 2010, Nr. 1, S. 65 – 86
-
Plk1 is a novel target for high-risk neuroblastoma therapyIn: Klinische Pädiatrie, Jg. 222, 2010, Nr. 3, S. 222 – A21
-
Production of chick embryo extract for the cultivation of murine neural crest stem cellsIn: JoVE, Jg. 2010, 2010, Nr. 45DOI, Online Volltext (Open Access)
-
The DNA-binding protein YB-1 is a direct MYCN target and influences repair and resistance in neuroblastoma cell linesIn: Klinische Pädiatrie, Jg. 222, 2010, Nr. 3, S. 219
-
The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumorsIn: Molecular Cancer Therapeutics, Jg. 9, 2010, Nr. 12, S. 3145 – 3157
-
ALK Mutation Analysis in Patients of the German Neuroblastoma StudyIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 195
-
Candidate Genes of 6 p Amplification in RetinoblastomaIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 208
-
Characterisation of stable cell clones derived from an unusual neuroblastoma stage 4S with MYCN amplificationIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 200
-
Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressivenessIn: Oncogene, Jg. 28, 2009, Nr. 19, S. 2015 – 2023
-
LSD 1 is a Potential Therapeutic Target in MedulloblastomaIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 203 – 204
-
Lysine-Specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : Implications for therapyIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. A61
-
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapyIn: Cancer Research, Jg. 69, 2009, Nr. 5, S. 2065 – 2071DOI (Open Access)
-
Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compoundsIn: Clinical Cancer Research, Jg. 15, 2009, Nr. 11, S. 3690 – 3696
-
MicroRNAs 221 and 222 in the Pathogenesis of Solid Childhood TumorsIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 210
-
MicroRNAs in the pathogenesis of neuroblastomaIn: Cancer Letters, Jg. 274, 2009, Nr. 1, S. 10 – 15
-
N-myc induces transformation of neural crest stem cells in vitro and in vivoIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 195
-
Overall genomic pattern is a predictor of outcome in neuroblastomaIn: Journal of clinical oncology, Jg. 27, 2009, Nr. 7, S. 1026 – 1033
-
Pharmacologic activation of the p53 pathway using Nutlin-3 inhibits medulloblastoma cell proliferation in vitroIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 201
-
Prognostic role and functional analyses of miRNA expression in neuroblastomaIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 206
-
Proteomics of neuroblastoma master regulatorsIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 209
-
Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome predictionIn: Cancer Letters, Jg. 282, 2009, Nr. 1, S. 55 – 62
-
The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivoIn: International Journal of Cancer, Jg. 124, 2009, Nr. 10, S. 2488 – 2494
-
The miR-17-92 gene cluster is amplified and overexpressed in retinoblastomaIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 195
-
Xenogeneic immunization with human tyrosine hydroxylase DNA vaccines suppresses growth of established neuroblastomaIn: Molecular Cancer Therapeutics, Jg. 8, 2009, Nr. 8, S. 2392 – 2401
-
A novel function of Aurora-A : kinase-independent stabilization of N-Myc protein in MYCN-amplified neuroblastomaIn: European journal of pediatrics, Jg. 167, 2008, Nr. 3, S. 372 – 372
-
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23In: BMC Cancer, Jg. 8, 2008, S. 173
-
Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cellsIn: DNA Repair, Jg. 7, 2008, Nr. 10, S. 1757 – 1764
-
Expression of the p75 neurotrophin receptor reduces tumorigenity of neuroblastoma cells in vivo and in vitroIn: Klinische Pädiatrie, Jg. 220, 2008, Nr. 3, S. 206
-
Expression of the tumour suppressor gene CADM1 is associated with favourable outcome and inhibits cell survival in neuroblastomaIn: Oncogene, Jg. 27, 2008, Nr. 23, S. 3329 – 3338
-
Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomicsIn: International Journal of Cancer, Jg. 122, 2008, Nr. 5, S. 1177 – 1182
-
Identification of potential new therapeutic and diagnostic targets for neuroblastoma using patient-derived autoantibodiesIn: Klinische Pädiatrie, Jg. 220, 2008, Nr. 3, S. 200
-
MYCN regulates oncogenic MicroRNAs in neuroblastomaIn: International Journal of Cancer, Jg. 122, 2008, Nr. 3, S. 699 – 704
-
Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapyIn: European journal of cancer, Jg. 44, 2008, Nr. 5, S. 699 – 709
-
Neurotrophin receptor expression in human primary retinoblastomas and retinoblastoma cell linesIn: Pediatric Blood and Cancer, Jg. 50, 2008, Nr. 2, S. 218 – 222
-
Photodynamic therapy in retinoblastoma : effects of verteporfin on retinoblastoma cell linesIn: Investigative Ophthalmology & Visual Science (IOVS), Jg. 49, 2008, Nr. 7, S. 3158 – 3163
-
Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cellsIn: Clinical Cancer Research, Jg. 14, 2008, Nr. 4, S. 1172 – 1181
-
The LSD 1 histone demethylase is highly expressed in poorly differentiated neuroblastoma and is a novel therpeutic targetIn: Klinische Pädiatrie, Jg. 220, 2008, Nr. 3, S. 208
-
The role of heat-shock protein 90 in neuroblastoma tumor biologyIn: Klinische Pädiatrie, Jg. 220, 2008, Nr. 3, S. 199
-
Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cellsIn: Cancer Letters, Jg. 271, 2008, Nr. 1, S. 56 – 63
-
ArrayCGH based classification of neuroblastoma into genomic subgroupsIn: Chromosome research, Jg. 15, 2007, Nr. Suppl. 2, S. 82 – 83
-
ArrayCGH-based classification of neuroblastoma into genomic subgroupsIn: Genes, chromosomes & cancer, Jg. 46, 2007, Nr. 12, S. 1098 – 1108
-
Correction : Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genesIn: Genome biology, Jg. 8, 2007, Nr. 1, S. 401
-
Evidence for tumour suppressor activity of IGSF4 in neuroblastornaIn: Klinische Pädiatrie, Jg. 219, 2007, Nr. 3, S. 189 – 189
-
Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cellsIn: Cancer Research, Jg. 67, 2007, Nr. 5, S. 2331 – 2338
-
High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumorsIn: International Journal of Cancer, Jg. 120, 2007, Nr. 3, S. 533 – 538
-
Initial characterization of two novel cell lines derived from primary Wilms' tumorsIn: Klinische Pädiatrie, Jg. 219, 2007, Nr. 3, S. 181
-
N-MYC regulates oncogenic micrornas in neuroblastomaIn: Pediatric Blood and Cancer, Jg. 49, 2007, Nr. 4, S. 429 – 429
-
N-Myc regulates oncogenic microRNAs in neuroblastomaIn: Klinische Pädiatrie, Jg. 219, 2007, Nr. 3, S. 192
-
N-Myc regulates oncogenic micrortnas in neuroblastomaIn: European Journal of Pediatrics, Jg. 166, 2007, Nr. 3, S. 278
-
Neurotrophin receptor status influences the capacity of nonhomologous DNA end joining INSY5Y neuroblastoma cellsIn: Klinische Pädiatrie, Jg. 219, 2007, Nr. 3, S. 187 – 187
-
Photodynamic therapy in retinoblastomaIn: Klinische Pädiatrie, Jg. 219, 2007, Nr. 3, S. 193 – 194
-
The mutagenic potential of non-homologous end joining in the absence of the NHEJ core factors Ku70/80, DNA-PKcs and XRCC4-LigIVIn: Mutagenesis, Jg. 22, 2007, Nr. 3, S. 217 – 233
-
Translating expression profiling into a clinically feasible test to predict neuroblastoma outcomeIn: Clinical Cancer Research, Jg. 13, 2007, Nr. 5, S. 1459 – 1465
-
Development of a neuroblastoma-specific tissue-microarray as a tool for time- and cost-effective immunohistochemistry analysesIn: Klinische Pädiatrie, Jg. 218, 2006, Nr. 3, S. 195
-
Expression of TrkA is a potential regulator of immunogenicity in neuroblastoma cellsIn: Klinische Pädiatrie, Jg. 218, 2006, Nr. 3, S. 192 – 192
-
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genesIn: Genome biology, Jg. 7, 2006, Nr. 9, S. R84
-
Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemiaIn: Clinical Cancer Research, Jg. 12, 2006, Nr. 8, S. 2434 – 2441
-
Isolation of CD3-/CD56+natural killer cells from whole blood derived buffy coatsIn: Bone Marrow Transplantation, Jg. 37, 2006, Nr. Suppl. 1, S. S303
-
MicroRNA expression analysis in neuroblastoma using pligonuclectide arraysIn: Klinische Pädiatrie, Jg. 218, 2006, Nr. 3, S. 194
-
Microarray analysis defines IPL/TSSC3 as a potential target mediating the synergistic effects of combined thermo-chemotherapy in neuroblastoma cellsIn: Klinische Pädiatrie, Jg. 218, 2006, Nr. 3, S. 192 – 193
-
VEGF plasma levels in non-ruptured intracranial aneurysmsIn: Neurosurgical Review, Jg. 29, 2006, Nr. 1, S. 26 – 29
-
Vascular endothelial growth factor plasma levels are significantly elevated in patients with cerebral arteriovenous malformationsIn: Cerebrovascular Diseases, Jg. 21, 2006, Nr. 3, S. 154 – 158
-
Application of microarray-based technology to neuroblastomaIn: Cancer letters, Jg. 228, 2005, Nr. 1-2, S. 13 – 20
-
Biological effects of TrkA and TrkB receptor signaling in neuroblastomaIn: Cancer letters, Jg. 228, 2005, Nr. 1-2, S. 143 – 153
-
Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastomaIn: Oncogene, Jg. 24, 2005, Nr. 42, S. 6441 – 6449
-
Gastrointestinale und hepatobiliäre InfektionenIn: Klinische Pädiatrie, Jg. 217, 2005, Nr. Suppl. 1, S. 101 – 109
-
Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemiaIn: Blood, Jg. 106, 2005, Nr. 11, S. 422A
-
Identification of dynamic proteome changes upon ligand activation of Trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometryIn: Molecular and Cellular Proteomics (MCP), Jg. 4, 2005, Nr. 3, S. 291 – 299
-
Identification of dynamic proteome changes upon ligand activation of trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometryIn: Molecular and Cellular Proteomics (MCP), Jg. 4, 2005, Nr. 8, S. 1210
-
Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomasIn: Oncogene, Jg. 24, 2005, Nr. 1, S. 165 – 177
-
Phox2B mutations and the Delta-Notch pathway in neuroblastomaIn: Cancer letters, Jg. 228, 2005, Nr. 1-2, S. 59 – 63
-
Prediction of clinical outcome and biological characterization of neuroblastoma by expression profilingIn: Oncogene, Jg. 24, 2005, Nr. 53, S. 7902 – 7912
-
Quantitative phenotyping and discriminant analysis improve scoring classification in late B-lymphoproliferative disordersIn: Blood, Jg. 106, 2005, Nr. 11, S. 422A
-
The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasivenessIn: Carcinogenesis, Jg. 26, 2005, Nr. 12, S. 2105 – 2115
-
Identification of new markers for the detection of minimal residual disease in AML by gene expression profiling and real time PCRIn: Blood, Jg. 104, 2004, Nr. 11, S. 554A
-
NT-3 mediated signaling pathways in DAOY medulloblastoma cellsIn: Neuro-Oncology, Jg. 6, 2004, Nr. 4, S. 409 – 409
-
The Phox2B homeobox gene is mutated in sporadic neuroblastomasIn: Oncogene, Jg. 23, 2004, Nr. 57, S. 9280 – 9288
-
Microarray-analysis : a new approach to study the molecular mechanisms of thermo-chemotherapyIn: Klinische Pädiatrie, Jg. 215, 2003, Nr. 6, S. 298 – 302
-
Proteomics : techniques and applications in cancer researchIn: Klinische Pädiatrie, Jg. 215, 2003, Nr. 6, S. 293 – 297
-
Expression of Apo-3 and Apo-3L in primitive neuroectodermal tumours of the central and peripheral nervous systemIn: European journal of cancer, Jg. 38, 2002, Nr. 1, S. 92 – 98
-
Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cellsIn: Cancer Research, Jg. 62, 2002, Nr. 6, S. 1802 – 1808
-
Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastomaIn: European journal of cancer, Jg. 38, 2002, Nr. 1, S. 83 – 91
-
Resistance to chemotherapy mediated by TrkB in neuroblastomasIn: Cancer Research, Jg. 62, 2002, Nr. 22, S. 6462 – 6466
-
Author Correction : The landscape of genomic alterations across childhood cancersIn: Nature. London: Springer Nature, Jg. 559, 2018, Nr. 7714, S. E10
-
First Prospective National Registry for Pediatric Eye Cancer in Germany and Austria
49th Congress of the International Society of Paediatric Oncology (SIOP), October 12–15, 2017, Washington, DC, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 64, 2017, Nr. Suppl. 3, S. S276 – S277 -
Long-term overall survival for patients with retinoblastoma : A report from the German referral center from 1940-2008
Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,In: Oncology Research and Treatment. Basel: Karger, Jg. 39, 2016, Nr. Suppl. 1, S. 29 – 30 -
Integrated Genomic Analysis Identifies Specific Alterations and Activation of Yap in Relapsed Neuroblastoma
47th Congress of the International Society of Paediatric Oncology (SIOP), October 8–11, 2015, Cape Town, South Africa,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 62, 2015, Nr. S4, S. S145 – S145 -
ALK F1174L kinase activity as driver of cell proliferation in neuroblastoma cell line models and neuroblastoma tumorsIn: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 72, 2012, Nr. 8, Suppl., S. 1683
-
Lysin-Specific Histone Dementhylase 1(LSD1) is a promising new Epigenetic Theapy target Crucially involved in the migration of Medulloblastoma Cells
15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 14, 2012, Nr. Suppl. 1, S. i92 -
miR-34a is dispensable for normal development but its loss Accelerates medulloblastoma formation
15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 14, 2012, Nr. Suppl. 1, S. 89 -
Long-term follow-up of patients receiving chemoreduction for intraocular rettinoblatoma in the German RB Center (1995-2004)
43rd Congress of the International Society of Paediatric Oncology (SIOP) 2011 ; 28th–30th October, 2011, Auckland, New Zealand,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 57, 2011, Nr. 5, S. 785 -
Long-term follow-up of pediatric patients receiving total body irradiation before bone marrow transplantation
43rd Congress of the International Society of Paediatric Oncology (SIOP) 2011 ; 28th–30th October, 2011, Auckland, New Zealand,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 57, 2011, Nr. 5, S. 827 -
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 812 -
Deep Sequencing Revals Differential Expression of Micrornas in Favourable Versus Unfavourable Neuroblastoma
42nd Congress of the International Society of Pediatric Oncology (SIOP) in Boston,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 826 – 827 -
High Expression of the alk Receptor Tyrosine Kinase Precedes Mutation as a Determining Factor of Unfavourable Phenotype in Primary Neuroblastoma
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 827 -
Pharmacologic Activation of the P53 Pathway by Nutlin-3 Inhibits Medulloblastoma Cell Proliferation in Vitro
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 918 -
Development of Guidelines for Parents with Children Neuwly Diagnosed with Cancer : Nutrition, Personal and Oral Hygiene
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 757 -
Exon-Level gene expression analysis of primary neuroblastomas improves risk prediction and identifies jaridic as a novel Therapeutic target
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 742 – 743 -
LSD1 is a Potential Therapeutic Target in Medulloblastoma
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, October 5–9, 2009, Sao Paulo, Brazil,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 826 -
Modeling Neuroblastomagenesis from neural crest Stem Cells in Vitro and in Vivo
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 703 – 704 -
The MIR-17-92 Gene Cluster is Amplified an overexpressed in Rettinoblastoma
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 735