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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Ceramides in cardiovascular disease : emerging role as independent risk predictors and novel therapeutic targetsIn: Cardiovascular Research, Jg. 121, 2025, Nr. 9, S. 1345 – 1358DOI (Open Access)
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PCSK9 Activity Is Potentiated Through HDL BindingIn: Circulation Research, Jg. 129, 2021, Nr. 11, S. 1039 – 1053DOI (Open Access)
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Prednisone prevents particle induced bone loss in the calvaria mouse modelIn: Heliyon, Jg. 7, 2021, Nr. 8, S. e07828DOI, Online Volltext (Open Access)
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A novel mechanism of ACE inhibition - associated enhanced platelet reactivity : Disproof of the ARB-MI paradox?In: European Journal of Clinical Pharmacology, Jg. 76, 2020, Nr. 9, S. 1245 – 1251
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Aspirin antiplatelet effects are associated with body weightIn: Vascular Pharmacology, Jg. 125-126, 2020, 106635
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Enhanced platelet reactivity under aspirin medication and major adverse cardiac and cerebrovascular events in patients with coronary artery diseaseIn: Pharmacology, Jg. 105, 2020, Nr. 1-2, S. 118 – 122
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Platelet reactivity in patients with chronic kidney disease and hemodialysisIn: Journal of Thrombosis and Thrombolysis, Jg. 49, 2020, Nr. 1, S. 168 – 172
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Response by Petzold et al to Letter Regarding Article, "rivaroxaban Reduces Arterial Thrombosis by Inhibition of Fxa-Driven Platelet Activation via Protease Activated Receptor-1"In: Circulation Research, Jg. 126, 2020, Nr. 10, S. E116 – E117DOI (Open Access)
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Response by Petzold et al to letter regarding article, "Rivaroxaban reduces arterial thrombosis by inhibition of FXa-driven platelet activation via protease activated receptor-1"In: Circulation Research, 2020, S. E54 – E55DOI (Open Access)
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Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1In: Circulation Research, Jg. 126, 2020, Nr. 4, S. 486 – 500DOI (Open Access)
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Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in miceIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS), Jg. 125, 2019, S. 1 – 7
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Antiplatelet effects of aspirin and clopidogrel after left atrial appendage (LAA) occluder implantationIn: International Journal of Cardiology, Jg. 275, 2019, S. 95 – 100
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Cardioprotection by very mild hypothermia in miceIn: Cardiovascular Diagnosis and Therapy, Jg. 9, 2019, Nr. 1, S. 64 – 67DOI, Online Volltext (Open Access)
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Dose reduction, oral application, and order of intake to preserve aspirin antiplatelet effects in dipyrone co-medicated chronic artery disease patientsIn: European Journal of Clinical Pharmacology, Jg. 75, 2019, Nr. 1, S. 13 – 20
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Platelet reactivity in patients on aspirin and clopidogrel therapy measured by a new bedside whole-blood assayIn: Journal of Cardiovascular Pharmacology, Jg. 73, 2019, Nr. 1, S. 40 – 47
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Potent anti-inflammatory properties of HDL in vascular smooth muscle cells mediated by HDL-S1P and their impairment in coronary artery disease due to lower HDL-S1P : A new aspect of HDL dysfunction and its therapyIn: The FASEB Journal, Jg. 33, 2019, Nr. 1, S. 1482 – 1495DOI (Open Access)
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Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophagesIn: Journal of Lipid Research, Jg. 60, 2019, Nr. 3, S. 506 – 515DOI (Open Access)
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Safety and efficacy of Tirofiban in STEMI-patientsIn: International Journal of Cardiology, Jg. 274, 2019, S. 35 – 39
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Aspirin inhibits platelet-derived sphingosine-1-phosphate induced endothelial cell migrationIn: Pharmacology, Jg. 101, 2018, Nr. 1-2, S. 72 – 75
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Platelet function testing: dead or aliveIn: Journal of Thrombosis and Haemostasis, Jg. 16, 2018, Nr. 5, S. 984 – 986DOI (Open Access)
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Structural basis of sterol binding and transport by a yeast StARkin domainIn: The Journal of Biological Chemistry (JBC), Jg. 293, 2018, Nr. 15, S. 5522 – 5531DOI (Open Access)
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Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone lossIn: Nature Medicine, Jg. 24, 2018, Nr. 5, S. 667 – 678
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Analgesic medication with dipyrone in patients with coronary artery disease : relation to MACCEIn: International Journal of Cardiology, Jg. 236, 2017, S. 76 – 81
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Cardiovascular Magnetic Resonance Relaxometry Predicts Regional Functional Outcome After Experimental Myocardial InfarctionIn: Circulation: Cardiovascular Imaging, Jg. 10, 2017, Nr. 8, S. e006025
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Dabigatran enhances platelet reactivity and platelet thrombin receptor expression in patients with atrial fibrillationIn: Journal of Thrombosis and Haemostasis, Jg. 15, 2017, Nr. 3, S. 473 – 476DOI (Open Access)
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Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasisIn: Blood, Jg. 130, 2017, Nr. 25, S. 2786 – 2798
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Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart diseaseIn: Journal of Molecular and Cellular Cardiology, Jg. 110, 2017, S. 35 – 37
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S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1ßIn: Journal of Experimental Medicine (JEM), Jg. 214, 2017, Nr. 9, S. 2695 – 2713DOI (Open Access)
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SeQuent Please vs. Pantera Lux drug coated balloon angioplasty in real life : results from the Düsseldorf DCB registryIn: International Journal of Cardiology, Jg. 231, 2017, S. 68 – 72
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Thromboxane formation assay to identify high on-treatment platelet reactivity to aspirinIn: Pharmacology, Jg. 100, 2017, Nr. 3-4, S. 127 – 130
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Antiplatelet effects of aspirin in chronic kidney disease patientsIn: Journal of Thrombosis and Haemostasis, Jg. 14, 2016, Nr. 2, S. 375 – 380DOI (Open Access)
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Dipyrone comedication in aspirin treated stroke patients impairs outcomeIn: Vascular Pharmacology, Jg. 87, 2016, S. 66 – 69
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Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in MiceIn: The Journal of Immunology (JI), Jg. 196, 2016, Nr. 4, S. 1655 – 1665
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Imaging Reveals the Connection Between Spontaneous Coronary Plaque Ruptures, Atherothrombosis, and Myocardial Infarctions in HypoE/SRBI-/- MiceIn: Journal of Nuclear Medicine (JNM), Jg. 57, 2016, Nr. 9, S. 1420 – 1427DOI (Open Access)
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Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic PreconditioningIn: Journal of the American Heart Association, Jg. 5, 2016, S. e003393DOI, Online Volltext (Open Access)
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Defects of high-density lipoproteins in coronary artery disease caused by low sphingosine-1-phosphate content : correction by sphingosine-1-phosphate -loadingIn: Journal of the American College of Cardiology (JACC), Jg. 66, 2015, Nr. 13, S. 1470 – 1485DOI (Open Access)
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HDL-S1P : Cardiovascular functions, disease-associated alterations, and therapeutic applicationsIn: Frontiers in Pharmacology, Jg. 6, 2015, S. 243DOI (Open Access)
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New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P(1))In: Bioorganic and Medicinal Chemistry Letters, Jg. 25, 2015, Nr. 22, S. 5048 – 5051
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Sphingosine-1-phosphate (S1P) inhibits TNFA-induced MMP-9 expression (TIME) through S1P2-mediated activation of PTENIn: Atherosclerosis, Jg. 241, 2015, Nr. 1, S. E76 – E77
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Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectinIn: Nature Communications, Jg. 6, 2015, S. 6416DOI (Open Access)
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Synthesis and Evaluation of Fluorinated Fingolimod (FTY720) Analogues for Sphingosine-1-Phosphate Receptor Molecular Imaging by Positron Emission TomographyIn: Journal of Medicinal Chemistry, Jg. 58, 2015, Nr. 8, S. 3471 – 3484
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Synthesis of new ligands for targeting the S1P1 receptorIn: Bioorganic and Medicinal Chemistry, Jg. 23, 2015, Nr. 5, S. 1011 – 1026
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Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclastsIn: Nature Communications, Jg. 5, 2014, S. 5215DOI (Open Access)
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HDL-Bound Sphingosine 1-Phosphate (S1P) Predicts the Severity of Coronary Artery AtherosclerosisIn: Cellular Physiology and Biochemistry, Jg. 34, 2014, Nr. 1, S. 172 – 184DOI (Open Access)
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Sphingosine-1-phosphate (s1p) affects neointima formation and remodeling through s1p2-induced inhibition of matrix-metalloproteinase 9In: Atherosclerosis, Jg. 235, 2014, Nr. 2, S. E158
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Synthesis of fluorinated analogues of sphingosine-1-phosphate antagonists as potential radiotracers for molecular imaging using positron emission tomographyIn: Bioorganic and Medicinal Chemistry, Jg. 22, 2014, Nr. 19, S. 5168 – 5181
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Apoptotic cells enhance sphingosine-1-phosphate receptor 1 dependent macrophage migrationIn: European Journal of Immunology, Jg. 43, 2013, Nr. 12, S. 3306 – 3313
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Loss of survivin influences liver regeneration and is associated with impaired aurora B functionIn: Cell Death and Differentiation, Jg. 20, 2013, Nr. 6, S. 834 – 844
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Cardiomyocyte-specific deletion of survivin causes global cardiac conduction defectsIn: Basic Research in Cardiology, Jg. 107, 2012, Nr. 6, S. 299
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Chronische Herzinsuffizienz : Partielle Reversibilität durch linksventrikuläre mechanische UnterstützungssystemeIn: Der Pathologe, Jg. 33, 2012, Nr. 3, S. 175 – 182
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Increase of ABCG2/BCRP + side population stem cells in the myocardium after ventricular unloadingIn: Virchows Archiv, Jg. 461, 2012, Nr. Suppl. 1, S. 263
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Increase of ABCG2/BCRP+ side population stem cells in myocardium after ventricular unloadingIn: The Journal of Heart and Lung Transplantation, Jg. 31, 2012, Nr. 3, S. 318 – 324
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The coronary circulation in cardioprotection : More than just one confounderIn: Cardiovascular Research, Jg. 94, 2012, Nr. 2, S. 237 – 245
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Acute vasomotor paralysis and potential downstream effects of paclitaxel from stents implanted for saphenous vein aorto-coronary bypass stenosisIn: Basic Research in Cardiology, Jg. 106, 2011, Nr. 4, S. 681 – 689
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Attenuated vasoconstrictor responses to coronary arterial aspirate from patients with paclitaxel eluting stent versus bare metal stent implantation for saphenous implantation for saphenous vein aorto-coronary bypass stenosisIn: Journal of the American College of Cardiology (JACC), Jg. 57, 2011, Nr. 14, S. E1092DOI (Open Access)
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Differential regulation of P-selectin-dependent rolling by Sphingosine-1-Phosphate (S1P) receptors S1P1 and S1P3In: Journal of Vascular Research, Jg. 48, 2011, Nr. Suppl. 1, S. 327
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Load-Reducing Therapy Prevents Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Plakoglobin-Deficient MiceIn: Journal of the American College of Cardiology (JACC), Jg. 57, 2011, Nr. 6, S. 740 – 750DOI (Open Access)
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Sphingosine-1-Phosphate Receptor 3 Promotes Recruitment of Monocyte/Macrophages in Inflammation and AtherosclerosisIn: Circulation Research, Jg. 108, 2011, Nr. 3, S. 314 – 323DOI (Open Access)
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Vasoconstrictor Potential of Coronary Aspirate From Patients Undergoing Stenting of Saphenous Vein Aortocoronary Bypass Grafts and Its Pharmacological AttenuationIn: Circulation Research, Jg. 108, 2011, Nr. 3, S. 344 – 352DOI (Open Access)
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Cardiomyocyte survivin protein expression is associated with cell size and DNA content in the failing human heart and is reversibly regulated after ventricular unloadingIn: The Journal of Heart and Lung Transplantation, Jg. 29, 2010, Nr. 11, S. 1286 – 1292
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Endothelial functions of sphingosine-1-phosphateIn: Cellular Physiology and Biochemistry, Jg. 26, 2010, Nr. 1, S. 87 – 96
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Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphateIn: Journal of Cellular Biochemistry, Jg. 109, 2010, Nr. 6, S. 1232 – 1243
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Hemodynamic support by left ventricular assist devices reduces cardiomyocyte DNA content in the failing human heartIn: Circulation, Jg. 121, 2010, Nr. 8, S. 989 – 996
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Inhibition of hyaluronan synthesis accelerates murine atherosclerosis : Novel insights into the role of hyaluronan synthesisIn: Circulation, Jg. 122, 2010, Nr. 22, S. 2313 – 2322
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Intravenous Sphingosylphosphorylcholine Protects Ischemic and Postischemic Myocardial Tissue in a Mouse Model of Myocardial Ischemia/Reperfusion InjuryIn: Mediators of Inflammation, 2010, 425191DOI (Open Access)
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Reverse remodeling after mechanical left ventricular unloading. Are stem cells involved?In: Fundamental and Clinical Pharmacology, Jg. 24, 2010, Nr. 1
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Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery diseaseIn: Basic Research in Cardiology, Jg. 105, 2010, Nr. 6, S. 821 – 832
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Ventricular unloading is associated with increased 20s proteasome protein expression in the myocardiumIn: The Journal of Heart and Lung Transplantation, Jg. 29, 2010, Nr. 1, S. 125 – 132
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Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferationIn: Liver International, Jg. 29, 2009, Nr. 4, S. 585 – 592
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Biglycan is required for adaptive remodeling after myocardial infarctionIn: Circulation, Jg. 117, 2008, Nr. 10, S. 1269 – 1276DOI (Open Access)
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Survivin determines cardiac function by controlling total cardiomyocyte numberIn: Circulation, Jg. 117, 2008, Nr. 12, S. 1583 – 1593
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Roles of cyclooxygenase-2 and phosphorylated Akt ⁽Thr³⁰⁸⁾ in cardiac hypertrophy regression mediated by left-ventricular unloadingIn: Journal of Thoracic and Cardiovascular Surgery, Jg. 133, 2007, Nr. 1, S. 37 – 43DOI (Open Access)
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Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient miceIn: Circulation, Jg. 114, 2006, Nr. 17, S. 1799 – 1806DOI (Open Access)
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Degraded collagen induces calpain-mediated apoptosis and destruction of the X-chromosome-linked inhibitor of apoptosis (xIAP) in human vascular smooth muscle cellsIn: Cardiovascular Research, Jg. 69, 2006, Nr. 3, S. 697 – 705DOI (Open Access)
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Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expressionIn: Virchows Archiv, Jg. 448, 2006, Nr. 1, S. 16 – 23
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Stress associated proteins metallothionein, HO-1 and HSP 70 in human zero-hour biopsies of transplanted kidneysIn: Virchows Archiv, Jg. 449, 2006, Nr. 2, S. 192 – 199
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High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome.In: Breast Cancer Research : BCR, Jg. 7, 2005, Nr. 2DOI (Open Access)
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Reverse remodeling following insertion of left ventricular assist devices (LVAD) : A review of the morphological and molecular changesIn: Cardiovascular Research, Jg. 68, 2005, Nr. 3, S. 376 – 386DOI (Open Access)
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HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3In: The Journal of Clinical Investigation (JCI), Jg. 113, 2004, Nr. 4, S. 569 – 581DOI (Open Access)
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Heat shock protein 72 and apoptosis indicate cardiac decompensation during early multiple organ failure in sheepIn: Intensive Care Medicine, Jg. 30, 2004, Nr. 7, S. 1405 – 1413
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Prognostic relevance of activated Akt kinase in node-negative breast cancer : A clinicopathological study of 99 casesIn: Modern Pathology, Jg. 17, 2004, Nr. 1, S. 15 – 21DOI (Open Access)
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Dynamic regulation of MEK/Erks and Akt/GSK-3β in human end-stage heart failure after left ventricular mechanical support : Myocardial mechanotransduction-sensitivity as a possible molecular mechanismIn: Cardiovascular Research, Jg. 59, 2003, Nr. 2, S. 390 – 399DOI (Open Access)
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Myokardiale Veränderungen unter mechanischer linksventrikulärer UnterstützungstherapieIn: Der Pathologe, Jg. 24, 2003, Nr. 2, S. 83 – 90
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Reduction of hypoxia-inducible heme oxygenase-1 in the myocardium after left ventricular mechanical supportIn: The Journal of Pathology, Jg. 197, 2002, Nr. 2, S. 230 – 237
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Survivin signalling in the heartIn: Journal of Molecular and Cellular Cardiology. Amsterdam: Elsevier, Jg. 50, 2011, Nr. 1, S. 6 – 8
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Sortilin evokes endothelial dysfunction and arterial hypertension through the dysregulation of sphingolipid metabolism and oxidative stress
ESC Congress 2020 – The Digital Experience 29 August – 1 September 2020,In: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 41, 2020, Nr. Supplement_2, S. 2704DOI (Open Access) -
Dapagliflozin reduces platelet activation and atherosclerosis
84th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 20th Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) ; 26 February – 1 March 2018. Göttingen,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 391, 2018, Nr. 1, Supplement, S. S30 -
Inhibition of the S1P lyase improves cardiac remodeling after acute myocardial infarction in miceIn: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 37, 2016, Nr. Suppl. 1, S. 630
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Sphingosine-1-phosphate receptor 3 modulates P-selectin dependent leukocyte rolling in vivoIn: European Journal of Clinical Investigation. Hoboken: Wiley & Sons, Jg. 45, 2015, Nr. Suppl. 2, Special Issue: Abstracts of the 49th Annual Scientific Meeting of the European Society for Clinical Investigation Cluj‐Napoca, Romania 27 – 30 May 2015, S. 48 – 49
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Deletion of the S1P receptor S1P3 attenuates macrophage-driven inflammation in atherosclerotic lesions of S1P3-/-/ApoE-/- double knockout miceIn: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 31, 2010, Nr. Suppl. 1, S. 159
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Increased plasma levels of non-high-density lipoprotein (HDL)-bound sphingosine 1-phosphate (S1P) in coronary artery disease are caused by alterations of S1P uptake into HDLIn: European Heart Journal. Oxford: Oxford University Press (OUP), Jg. 31, 2010, Nr. Suppl. 1, S. 103
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MS528 Increased plasma levels of non-HDL-bound Sphingosine-1-Phosphate (S1P) in coronary artery disease are caused by alterations of S1P uptake by HDLIn: Atherosclerosis Supplements: Elsevier, Jg. 11, 2010, Nr. 2, S. 216
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Sphingosine-1 phosphate receptor 3 promotes macrophage recruitment to atherosclerotic lesionsIn: Cardiovascular Research. Oxford: Oxford University Press (OUP), Jg. 87, 2010, Nr. Suppl. 1, S. S90
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Cardiovascular effects of sphingosine-1-phosphate (S1P)In: Sphingolipids in Disease / Gulbins, Erich; Petrache, Irina. Wien [u.a.]: Springer, 2013, S. 147 – 170
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Sphingosine 1-Phosphate (S1P) Signaling in Cardiovascular Physiology and DiseaseIn: Lysophospholipid Receptors: Signaling and Biochemistry / Chun, Jerold (Hrsg.). Hoboken, NJ: John Wiley and Sons, 2013, S. 283 – 312