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Universitätsprofessor/in, Innere Klinik (Tumorforschung)
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple MyelomaIn: Cancers Jg. 15 (2023) Nr. 8, 2373Online Volltext: dx.doi.org/ (Open Access)
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Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cellsIn: British Journal of Haematology Jg. 202 (2023) Nr. 5, S. 1033 - 1048Online Volltext: dx.doi.org/ (Open Access)
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Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapyIn: Blood Jg. 142 (2023) Nr. 25, S. 2175 - 2191Online Volltext: dx.doi.org/ (Open Access)
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Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cellsIn: British Journal of Haematology Jg. 196 (2022) Nr. 4, S. 995 - 1006Online Volltext: dx.doi.org/ (Open Access)
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GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemiaIn: Leukemia Jg. 36 (2022) Nr. 9, S. 2196 - 2207Online Volltext: dx.doi.org/ (Open Access)
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High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid LeukemiaIn: Cancers Jg. 14 (2022) Nr. 3, 486Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibitionIn: Frontiers in Oncology Jg. 12 (2022) 903691Online Volltext: dx.doi.org/ (Open Access)
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Expansion of functional personalized cells with specific transgene combinations.In: Nature Communications Jg. 9 (2018) Nr. 1, S. 994Online Volltext: dx.doi.org/ (Open Access)
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Gfi1b : A key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndromeIn: Haematologica / The Hematology Journal Jg. 103 (2018) Nr. 4, S. 614 - 625Online Volltext: dx.doi.org/ (Open Access)
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Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scalesIn: Journal of Extracellular Vesicles (JEV) Jg. 7 (2018) Nr. 1, S. 1528109Online Volltext: dx.doi.org/ (Open Access)
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GFI1B-A novel oncosuppressor which restricts number of leukemic stem stellsIn: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 2, S. 204 - 204
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Growth factor independence 1 (GFI !) regulates the AML supporting function of mesenchymal stromal cellsIn: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 2, S. 459 - 459
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Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent mannerIn: Haematologica / The Hematology Journal Jg. 101 (2016) Nr. 10, S. 1216 - 1227Online Volltext: dx.doi.org/ (Open Access)
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GFI136N as a therapeutic and prognostic marker for myelodysplastic syndromeIn: Experimental Hematology Jg. 44 (2016) Nr. 7, S. 590 - 595.e1Online Volltext: dx.doi.org/ (Open Access)
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Cytomegalovirus induces apoptosis in acute leukemia cells as a virus-versus-leukemia functionIn: Leukemia and Lymphoma Jg. 56 (2015) Nr. 11, S. 3189 - 3197Online Volltext: dx.doi.org/
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Complementation of non-tumorigenicity of HPV18-positive cervical carcinoma cells involves differential mRNA expression of cellular genes including potential tumor suppressor genes on chromosome 11q13In: Cancer Genetics Jg. 206 (2013) Nr. 7-8, S. 279 - 292Online Volltext: dx.doi.org/
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Free soluble HLA-G molecules but not exosome-derived soluble HLA-G molecules are of prognostic relevance in lung cancer patientsIn: Tissue Antigens Jg. 81 (2013) Nr. 5, S. 282 - 283Online Volltext: dx.doi.org/
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Gfi1 as a novel prognostic marker and tumor suppressor in acute myeloid leukemiaIn: Onkologie Jg. 36 7 (2013) S. 193 - 193
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Immuno-modulatory properties of primary-like immortalized stroma cell lines from leukemia patientsIn: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 270 - 271
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Pluripotent stem cells escape from senescenceassociated DNA methylation changesIn: Genome Research Jg. 23 (2013) Nr. 2, S. 248 - 259Online Volltext: dx.doi.org/ (Open Access)
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Abundance of a NOTCH1 mutated clone affects clinical outcome of patients with chronic lymphocytic leukemiaIn: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 97 - 97
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Genetic modification of the oxygen-sensing pathway alters the develoment of early thymic progenitorsIn: Experimental Hematology Jg. 40 (2012) Nr. 8, Suppl. 1, S. 21 - 22
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Immunomodulatory activity in the supernatants of novel human bone marrow stroma cell lines from a normal donor and leukemia patientsIn: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 120 - 121
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Novel human bone marrow stroma cell lines from a normal donor and leukemia and lymphoma patients
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 260Online Volltext: dx.doi.org/ -
Telomeres and prognosis in patients with chronic lymphocytic leukaemiaIn: International Journal of Hematology Jg. 93 (2011) Nr. 1, S. 74 - 82Online Volltext: dx.doi.org/
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Prognostic relevance of soluble human leukocyte antigen-G and total human leukocyte antigen class I molecules in lung cancer patientsIn: Human Immunology Jg. 71 (2010) Nr. 5, S. 489 - 495Online Volltext: dx.doi.org/
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Interaction of Adenovirus E1A with the HHV8 Promoter of Latent Genes : E1A Proteins are Able to Activate the HHV-8 LANAp in MV3 Reporter CellsIn: The Open Virology Journal Jg. 12 (2008) S. 61 - 68Online Volltext: dx.doi.org/ (Open Access)
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Impfung gegen Krebs : TumorvakzinenIn: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 100 - 109Online Volltext (Open Access)
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Thalidomide in combination with vincristine, epirubicin and dexamethasone (VED) for previously untreated patients with multiple myelomaIn: European Journal of Haematology Jg. 74 (2005) Nr. 1, S. 40 - 46Online Volltext: dx.doi.org/
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The bone marrow niche as a potential target to improve the outcome of acute myeoloid leukemia using dexamethasone
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 73 - 74Online Volltext: dx.doi.org/ (Open Access) -
Establishment of a real-time PCR assay to quantify the size of a NOTCH1 mutated subclone in chronic lymphocytic leukemia
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 60Online Volltext: dx.doi.org/ -
Mice with thymic epithelial deletion of the von Hippel-Lindau gene are lacking a functioning thymusIn: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 276
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Vav-iCre mediated deletion of the von hippel lindau gene does not alter the cell cycle status of hematopoietic stem cells in vivoIn: Experimental Hematology
New York Jg. 40 (2012) Nr. 8, Suppl. 1, S. 101 -
Cytomegalovirus increases incidence of acute GvHD and reduces the relapse risk for acute leukaemia after transplant : there is a virus-versus-leukaemia effect
EBMT (European Group for Blood and Bone Marrow Transplantation) 2010. March 21-14, 2010. Vienna, Austria,In: Bone Marrow Transplantation Jg. 45 (2010) Nr. Suppl. 2, S. S79Online Volltext: dx.doi.org/ -
Heterogeneous Interactions of Leukemic and Control Bone Marrow Stroma Cells with an AML Cell Line and AML Leukemic BlastsIn: Blood Jg. 116 (2010) Nr. 21, S. 460Online Volltext: dx.doi.org/
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Heterogeneous interactions of leukemic and control bone marrow stroma cells with an AML cell line and AML leukemic blasts
Deutsche, Österreichische und Schweizerische Gesellschaften für Hämatologie und Onkologie Jahrestagung, Berlin, Oktober 2010,In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 235Online Volltext: dx.doi.org/