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Prof. Dr. phil. nat. Fritz Sörgel

Funktionen

  • Nebenberuflich Lehrende/r, Institut für Pharmakologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Nau, Roland; Seele, Jana; Reichard, Utz; Sörgel, Fritz
    Antibacterial therapy in central nervous system infections : Breakpoints versus minimal inhibitory concentrations related to body fluid levels
    In: Infection - A Journal of Infectious Disease, 2025, in press
    DOI
  • Naumann, Hans Theodor; Höhl, Rainer; Kinzig, Martina; Salat, Sophie; Bartsch, Vanessa; Sörgel, Fritz; Bertram, Ralph; Steinmann, Jörg; Jensen, Anke; von Fragstein, Axel; Nentwich, Jens; Baumgärtel, Matthias; Haarmeyer, Golo-Sung; Geise, Arnim
    Correction to: High rates of cefiderocol plasma target attainment: results of a retrospective cohort study in 31 critically ill ICU patients
    In: Critical Care: The Online Intensive Care Journal, Jg. 29, 2025, 380
    DOI (Open Access)
  • Horkovics-Kovats, Stefan; Federič, Jozef; Kinzig, Martina; Sörgel, Fritz
    Disintegration-dissolution modeling of bilayer tablets : Predicting plasma profiles and antimicrobial efficacy under postprandial conditions
    In: Journal of Pharmaceutical Sciences, Jg. 114, 2025, Nr. 8, 103843
    DOI
  • Marx, Kathrin; Malmström, Nina; Quast, Marie; Glas, Annette; Wendt, Ralph; Kinzig, Martina; Sörgel, Fritz; Fedders, Maike; Bertsche, Thilo; Lübbert, Christoph
    Monitoring Plasma Concentrations of Intravenously Administered Fosfomycin to Prevent Drug-Related Adverse Events : A Retrospective Observational Study
    In: Antibiotics, Jg. 14, 2025, Nr. 6, 548
    DOI (Open Access)
  • Höhl, Rainer; Rasshofer, Fabian; Kinzig, Martina; Sörgel, Fritz; Hitzl, Wolfgang; Bertram, Ralph; Steinmann, Jörg
    Underexposure of linezolid in critically ill patients with extracorporeal membrane oxygenation (ECMO) : results from a monocentric study including blood samples from 52 patients
    In: Infection - A Journal of Infectious Disease, 2025, in press
    DOI
  • Naumann, Hans Theodor; Höhl, Rainer; Kinzig, Martina; Salat, Sophie; Bartsch, Vanessa; Sörgel, Fritz; Bertram, Ralph; Steinmann, Joerg; Jensen, Anke; von Fragstein, Axel; Nentwich, Jens; Baumgärtel, Matthias; Haarmeyer, Golo-Sung; Geise, Arnim
    High rates of cefidercol plasma target attainment : results of a retrospective cohort study in 31 critically ill ICU patients
    In: Critical Care: The Online Intensive Care Journal, Jg. 28, 2024, Nr. 1, 438
    DOI (Open Access)
  • Bertram, Ralph; Naumann, Hans-Theodor; Bartsch, Vanessa; Hitzl, Wolfgang; Kinzig, Martina; Haarmeyer, Golo-Sung; Baumgärtel, Matthias; Geise, Arnim; Muschner, Dorothea; Nentwich, Jens; John, Stefan; Sörgel, Fritz; Steinmann, Jörg; Höhl, Rainer
    Clinical and demographic factors affecting trough levels of isavuconazole in critically ill patients with or without COVID-19
    In: Mycoses, Jg. 66, 2023, Nr. 12, S. 1071 – 1078
    DOI (Open Access)
  • Purkiewicz, Aleksandra; Pietrzak-Fiećko, Renata; Sörgel, Fritz; Kinzig, Martina
    Caffeine, Paraxanthine, Theophylline, and Theobromine Content in Human Milk
    In: Nutrients, Jg. 14, 2022, Nr. 11, 2196
    DOI (Open Access)
  • Lingscheid, Tilman; Kinzig, Martina; Krüger, Anne; Müller, Nils; Bölke, Georg; Tober-Lau, Pinkus; Münn, Friederike; Kriedemann, Helene; Witzenrath, Martin; Sander, Leif E.; Sörgel, Fritz; Kurth, Florian
    Pharmacokinetics of Nirmatrelvir and Ritonavir in COVID-19 Patients with End-Stage Renal Disease on Intermittent Hemodialysis
    In: Antimicrobial Agents and Chemotherapy, Jg. 66, 2022, Nr. 11, e0122922
    DOI (Open Access)
  • Lahmer, Tobias; Erber, Johanna; Schmid, Roland M.; Schneider, Jochen; Spinner, Christoph D.; Luppa, Peter; Sörgel, Fritz; Kinzig, Martina; Rasch, Sebastian
    SARS-CoV-2 viral load dynamics in immunocompromised critically ill patients on remdesivir treatment
    In: Multidisciplinary Respiratory Medicine, Jg. 17, 2022, 825
    DOI (Open Access)
  • Nau, Roland; Sörgel, Fritz; Eiffert, Helmut
    Central nervous system infections and antimicrobial resistance : An evolving challenge
    In: Current Opinion in Neurology, Jg. 34, 2021, Nr. 3, S. 456 – 467
    DOI
  • Lahmer, Tobias; Batres Baires, Gonzalo; Schmid, Roland M.; Wiessner, Johannes R.; Ulrich, Jörg; Reichert, Maximilian; Huber, Wolfgang; Sörgel, Fritz; Kinzig, Martina; Rasch, Sebastian; Mayr, Ulrich
    Penetration of isavuconazole in ascites fluid of critically ill patients
    In: Journal of Fungi, Jg. 7, 2021, Nr. 5, 376
    DOI (Open Access)
  • Sörgel, Fritz; Malin, Jakob J.; Hagmann, Henning; Kinzig, Martina; Bilal, Muhammad; Eichenauer, Dennis A.; Scherf-Clavel, Oliver; Simonis, Alexander; El Tabei, Lobna; Fuhr, Uwe; Rybniker, Jan
    Pharmacokinetics of remdesivir in a COVID-19 patient with end-stage renal disease on intermittent haemodialysis
    In: Journal of Antimicrobial Chemotherapy, Jg. 76, 2021, Nr. 3, S. 825 – 827
    DOI (Open Access)
  • Li, Xia; Junge, Lisa; Taubert, Max; von Georg, Anabelle; Dahlinger, Dominik; Starke, Chris; Frechen, Sebastian; Stelzer, Christoph; Kinzig, Martina; Sörgel, Fritz; Jaehde, Ulrich; Töx, Ulrich; Goeser, Tobias; Fuhr, Uwe
    A Novel Study Design Using Continuous Intravenous and Intraduodenal Infusions of Midazolam and Voriconazole for Mechanistic Quantitative Assessment of Hepatic and Intestinal CYP3A Inhibition
    In: Journal of Clinical Pharmacology, Jg. 60, 2020, Nr. 9, S. 1237 – 1253
    DOI (Open Access)
  • van Saet, Annewil; Zeilmaker-Roest, Gerdien A.; van Hoeven, Marloes P.J.; Koch, Birgit C.P.; van Rosmalen, Joost; Kinzig, Martina; Sörgel, Fritz; Wildschut, Enno D.; Stolker, Robert J.; Tibboel, Dick; Bogers, Ad J.J.C.
    In Vitro Recovery of Sufentanil, Midazolam, Propofol, and Methylprednisolone in Pediatric Cardiopulmonary Bypass Systems
    In: Journal of Cardiothoracic and Vascular Anesthesia, Jg. 34, 2020, Nr. 4, S. 972 – 980
    DOI (Open Access)
  • Landersdorfer, Cornelia B.; Kinzig, Martina; Höhl, Rainer; Kempf, Peter; Nation, Roger L.; Sörgel, Fritz
    Physiologically Based Population Pharmacokinetic Modeling Approach for Ciprofloxacin in Bone of Patients Undergoing Orthopedic Surgery
    In: ACS Pharmacology & Translational Science, Jg. 3, 2020, Nr. 3, S. 444 – 454
    DOI, Online Volltext (Open Access)
  • Li, Xia; Höhl, Rainer; Sörgel, Fritz; Fuhr, Uwe
    The parent drugs chloroquine and hydroxychloroquine do not inhibit human CYP3A activity in vitro
    In: European Journal of Clinical Pharmacology, Jg. 76, 2020, Nr. 10, S. 1481 – 1482
    DOI (Open Access)
  • Grandoch, Maria; Flögel, Ulrich; Virtue, Sam; Maier, Julia K.; Jelenik, Tomas; Kohlmorgen, Christina; Feldmann, Kathrin; Ostendorf, Yanina; Castañeda, Tamara R.; Zhou, Zhou; Yamaguchi, Yu; Nascimento, Emmani B. M.; Sunkari, Vivekananda G.; Goy, Christine; Kinzig, Martina; Sörgel, Fritz; Bollyky, Paul L.; Schrauwen, Patrick; Al-Hasani, Hadi; Roden, Michael; Keipert, Susanne; Vidal-Puig, Antonio; Jastroch, Martin; Haendeler, Judith; Fischer, Jens W.
    4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue
    In: Nature Metabolism, Jg. 1, 2019, Nr. 5, S. 546 – 559
    DOI, Online Volltext (Open Access)
  • Trueck, Christina; Hsin, Chih-hsuan; Scherf-Clavel, Oliver; Schaeffeler, Elke; Lenssen, Rebekka; Gazzaz, Malaz; Gersie, Marleen; Taubert, Max; Quasdorff, Maria; Schwab, Matthias; Kinzig, Martina; Sörgel, Fritz; Stoffel, Marc S.; Fuhr, Uwe
    A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin
    In: Clinical Pharmacology & Therapeutics, Jg. 106, 2019, Nr. 6, S. 1398 – 1407
    DOI
  • Scherf-Clavel, Oliver; Kinzig, Martina; Stoffel, Marc S.; Fuhr, Uwe; Sörgel, Fritz
    A HILIC-MS/MS assay for the quantification of metformin and sitagliptin in human plasma and urine : A tool for studying drug transporter perturbation
    In: Journal of Pharmaceutical and Biomedical Analysis, Jg. 175, 2019, S. 112754
    DOI
  • Zilker, Markus; Sörgel, Fritz; Holzgrabe, Ulrike
    A long-time stability study of 50 drug substances representing common drug classes of pharmaceutical use
    In: Drug Testing and Analysis, Jg. 11, 2019, Nr. 7, S. 1065 – 1075
    DOI
  • Zilker, Markus; Sörgel, Fritz; Holzgrabe, Ulrike
    A systematic review of the stability of finished pharmaceutical products and drug substances beyond their labeled expiry dates
    In: Journal of Pharmaceutical and Biomedical Analysis, Jg. 166, 2019, S. 222 – 235
    DOI
  • Fuhr, Uwe; Hsin, Chih-Hsuan; Li, Xia; Jabrane, Wafaa; Sörgel, Fritz
    Assessment of pharmacokinetic drug-drug interactions in humans : In vivo probe substrates for drug metabolism and drug transport revisited
    In: Annual Review of Pharmacology and Toxicology, Jg. 59, 2019, S. 507 – 536
    DOI
  • Bulitta, Jürgen B.; Jiao, Yuanyuan; Landersdorfer, Cornelia B.; Sutaria, Dhruvitkumar S.; Tao, Xun; Shin, Eunjeong; Höhl, Rainer; Holzgrabe, Ulrike; Stephan, Ulrich; Sörgel, Fritz
    Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics
    In: Pharmaceutics, Jg. 11, 2019, Nr. 7, 323
    DOI (Open Access)
  • Bulitta, Jürgen B.; Jiao, Yuanyuan; Drescher, Stefanie K.; Oliver, Antonio; Louie, Arnold; Moya, Bartolome; Tao, Xun; Wittau, Mathias; Tsuji, Brian T.; Zavascki, Alexandre P.; Shin, Beom Soo; Drusano, George L.; Sörgel, Fritz; Landersdorfer, Cornelia B.
    Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis
    In: Clinical Pharmacokinetics, Jg. 58, 2019, Nr. 2, S. 143 – 156
    DOI
  • Lahmer, Tobias; Batres Baires, Gonzalo; Heilmaier, Markus; Schmid, Roland M.; Sörgel, Fritz; Kinzig, Martina; Huber, Wolfgang; Mayr, Ulrich; Rasch, Sebastian
    Influence of sustained low-efficiency dialysis treatment on isavuconazole plasma levels in critically Ill patients
    In: Antimicrobial Agents and Chemotherapy, Jg. 63, 2019, Nr. 11, S. e01162 – 19
    DOI, Online Volltext (Open Access)
  • Higel, Fabian; Sandl, Theresa; Kao, Chi-Ya; Pechinger, Nicole; Sörgel, Fritz; Friess, Wolfgang; Wolschin, Florian; Seidl, Andreas
    N-glycans of complex glycosylated biopharmaceuticals and their impact on protein clearance
    In: European Journal of Pharmaceutics and Biopharmaceutics, Jg. 139, 2019, S. 123 – 131
    DOI (Open Access)
  • Shah, Nirav R.; Bulitta, Jürgen B.; Kinzig, Martina; Landersdorfer, Cornelia B.; Jiao, Yuanyuan; Sutaria, Dhruvitkumar S.; Tao, Xun; Höhl, Rainer; Holzgrabe, Ulrike; Kees, Frieder; Stephan, Ulrich; Sörgel, Fritz
    Novel population pharmacokinetic approach to explain the differences between cystic fibrosis patients and healthy volunteers via protein binding
    In: Pharmaceutics, Jg. 11, 2019, Nr. 6, 286
    DOI (Open Access)
  • Scherf-Clavel, Oliver; Kinzig, Martina; Stoffel, Marc S.; Fuhr, Uwe; Sörgel, Fritz
    Quantification of adefovir and pitavastatin in human plasma and urine by LC-MS/MS : A useful tool for drug-drug interaction studies
    In: Journal of Chromatography B, Jg. 1125, 2019, S. 121718
    DOI
  • Zeiner; Kinzig; Divé; Maurer; Filipski; Harter; Senft; Bähr; Hattingen; Steinbach; Sörgel, Fritz; Voss; Steidl; Ronellenfitsch
    Regorafenib CSF Penetration, Efficacy, and MRI Patterns in Recurrent Malignant Glioma Patients
    In: Journal of Clinical Medicine (JCM), Jg. 8, 2019, Nr. 12, 2031
    DOI (Open Access)
  • Scherf-Clavel, Oliver; Kinzig, Martina; Besa, Axel; Schreiber, André; Bidmon, Clemens; Abdel-Tawab, Mona; Wohlfart, Jonas; Sörgel, Fritz; Holzgrabe, Ulrike
    The contamination of valsartan and other sartans, Part 2 : Untargeted screening reveals contamination with amides additionally to known nitrosamine impurities
    In: Journal of Pharmaceutical and Biomedical Analysis, Jg. 172, 2019, S. 278 – 284
    DOI
  • Sörgel, Fritz; Kinzig, Martina; Abdel-Tawab, Mona; Bidmon, Clemens; Schreiber, André; Ermel, Steffen; Wohlfart, Jonas; Besa, Axel; Scherf-Clavel, Oliver; Holzgrabe, Ulrike
    The contamination of valsartan and other sartans, part 1 : New findings
    In: Journal of Pharmaceutical and Biomedical Analysis, Jg. 172, 2019, S. 395 – 405
    DOI
  • Zilker, Markus; Sörgel, Fritz; Holzgrabe, Ulrike
    A stability-study of expired ampoules manufactured more than 40 years ago
    In: Journal of Pharmaceutical and Biomedical Analysis, Jg. 150, 2018, S. 318 – 326
    DOI
  • Munz, Martin; Pretscher, Dominik; Wilhelm, Martin; Holzgrabe, Ulrike; Sörgel, Fritz; Birkmann, Josef
    Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 56, 2018, Nr. 3, S. 142 – 147
    DOI
  • Gazzaz, Malaz; Kinzig, Martina; Schaeffeler, Elke; Jübner, Martin; Hsin, Chih-hsuan; Li, Xia; Taubert, Max; Trueck, Christina; Iltgen-Breburda, Juliane; Kraus, Daria; Queckenberg, Christian; Stoffel, Marc; Schwab, Matthias; Sörgel, Fritz; Fuhr, Uwe
    Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P-Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A : So What?
    In: Clinical Pharmacology & Therapeutics, Jg. 104, 2018, Nr. 6, S. 1249 – 1259
    DOI
  • Jiao, Yuanyuan; Kim, Tae Hwan; Tao, Xun; Kinzig, Martina; Landersdorfer, Cornelia B.; Drescher, Stefanie K.; Sutaria, Dhruvitkumar S.; Moya, Bartolome; Holzgrabe, Ulrike; Sörgel, Fritz; Bulitta, Jürgen B.
    First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers
    In: European Journal of Pharmaceutical Sciences, Jg. 123, 2018, S. 416 – 428
    DOI
  • Sigaroudi, Ali; Kinzig, Martina; Wahl, Oliver; Stelzer, Christoph; Schroeter, Michael; Fuhr, Uwe; Holzgrabe, Ulrike; Sörgel, Fritz
    Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid : A Pharmacokinetic Assessment of Central Nervous System Adverse Effects
    In: Pharmacology, Jg. 102, 2018, Nr. 3-4, S. 133 – 137
    DOI
  • Sigaroudi, Ali; Kinzig, Martina; Wahl, Oliver; Stelzer, Christoph; Schroeter, Michael; Fuhr, Uwe; Holzgrabe, Ulrike; Sörgel, Fritz
    Quantification of bisoprolol and metoprolol in simultaneous human serum and cerebrospinal fluid samples
    In: Pharmacology, Jg. 101, 2018, Nr. 1-2, S. 29 – 34
    DOI (Open Access)
  • Lübbert, Christoph; Baars, Christian; Dayakar, Anil; Lippmann, Norman; Rodloff, Arne C.; Kinzig, Martina; Sörgel, Fritz
    Environmental pollution with antimicrobial agents from bulk drug manufacturing industries in Hyderabad, South India, is associated with dissemination of extended-spectrum beta-lactamase and carbapenemase-producing pathogens
    In: Infection - A Journal of Infectious Disease, Jg. 45, 2017, Nr. 4, S. 479 – 491
    DOI
  • Sörgel, Fritz; Höhl, R.; Glaser, R.; Stelzer, C.; Munz, M.; Vormittag, M.; Kinzig, M.; Bulitta, J.; Landersdorfer, C.; Junger, A.; Christ, M.; Wilhelm, M.; Holzgrabe, U.
    Pharmakokinetik und Pharmakodynamik von Antibiotika in der Intensivmedizin
    In: Medizinische Klinik - Intensivmedizin und Notfallmedizin, Jg. 112, 2017, Nr. 1, S. 11 – 22
    DOI
  • Diekstra, M.H.; Fritsch, A.; Kanefendt, F.; Swen, J.J.; Djar, Moes; Sörgel, Fritz; Kinzig, M.; Stelzer, C.; Schindele, D.; Gauler, Thomas; Hauser, S.; Houtsma, D.; Roessler, M.; Moritz, B.; Mross, K.; Bergmann, L.; Oosterwijk, E.; Kiemeney, L.A.; Guchelaar, H.J.; Jaehde, U.
    Population modeling integrating pharmacokinetics, pharmacodynamics, pharmacogenetics, and clinical outcome in patients with sunitinib-treated cancer
    In: CPT: Pharmacometrics and Systems Pharmacology, Jg. 6, 2017, Nr. 9, S. 604 – 613
    DOI (Open Access)
  • Munz, Martin; Grummich, Hans; Birkmann, Josef; Wilhelm, Martin; Holzgrabe, Ulrike; Sörgel, Fritz
    Severe Drug-Induced Liver Injury as an Adverse Drug Event of Antibiotics : a Case Report and Review of the Literature
    In: Chemotherapy, Jg. 62, 2017, Nr. 6, S. 367 – 373
    DOI
  • Schiestl, Martin; Zabransky, Markus; Sörgel, Fritz
    Ten years of biosimilars in Europe : development and evolution of the regulatory pathways
    In: Drug Design, Development and Therapy, Jg. 11, 2017, S. 1509 – 1515
    DOI (Open Access)
  • Sigaroudi, Ali; Stelzer, Christoph; Braun, Tina; Frechen, Sebastian; Hüttner, Sven; Schröter, Michael; Kinzig, Martina; Fuhr, Uwe; Holzgrabe, Ulrike; Sörgel, Fritz
    Comparison of Pantoprazole Concentrations in Simultaneous Cerebrospinal Fluid and Serum Samples
    In: Pharmacology, Jg. 98, 2016, Nr. 1-2, S. 70 – 72
    DOI
  • Steffens, Michael; Paul, Tanusree; Hichert, Vivien; Scholl, Catharina; von Mallek, Dirk; Stelzer, Christoph; Sörgel, Fritz; Reiser, Bärbel; Schumann, Christian; Rüdiger, Stefan; Boeck, Stefan; Heinemann, Volker; Kächele, Volker; Seufferlein, Thomas; Stingl, Julia
    Dosing to rash? : The role of erlotinib metabolic ratio from patient serum in the search of predictive biomarkers for EGFR inhibitor-mediated skin rash
    In: European Journal of Cancer (EJC), Jg. 55, 2016, S. 131 – 139
    DOI
  • Higel, Fabian; Friess, Wolfgang; Sörgel, Fritz; Seidl, Andreas
    N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins
    In: European Journal of Pharmaceutics and Biopharmaceutics, Jg. 100, 2016, S. 94 – 100
    DOI (Open Access)
  • Valent, Peter; Sörgel, Fritz; Müller, Markus; Kornek, Gabriela Verena; Jäger, Ulrich; Kovar, Heinrich; Lassmann, Hans; Valenta, Rudolf; Smolen, Josef Sebastian; Stingl, Georg; Kerjaschki, Dontscho I.; Penninger, Josef Martin; Zielinski, Christoph C.; Kralovics, Robert; Busslinger, Meinrad; Superti-Furga, Giulio; Schumacher, Udo; Groner, Bernd
    Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine
    In: Journal of Innate Immunity, Jg. 8, 2016, Nr. 2, S. 111 – 120
    DOI
  • Erbguth, Frank; Hamacher-Erbguth, Angelika; Fuhr, Uwe; Sörgel, Fritz
    Adverse events during placebo vs. no drug administration : results of a randomised interventional trial in 160 volunteers
    In: European Journal of Clinical Pharmacology, Jg. 71, 2015, Nr. 11, S. 1403 – 1405
    DOI
  • Sörgel, Fritz; Schwebig, Arnd; Holzmann, Johann; Prasch, Stefan; Singh, Pritibha; Kinzig, Martina
    Comparability of Biosimilar Filgrastim with Originator Filgrastim: : Protein Characterization, Pharmacodynamics, and Pharmacokinetics
    In: BioDrugs, Jg. 29, 2015, Nr. 2, S. 123 – 131
    DOI (Open Access)
  • Theuretzbacher, Ursula; Ambrose, Paul G; MacGowan, Alasdair P; Andes, David R; Sörgel, Fritz; Derendorf, Hartmut; Mouton, Johan W; Drusano, George L; Tulkens, Paul M; Dudley, Michael N; Cars, Otto; Nation, Roger L
    In Memoriam : William A. Craig
    In: Antimicrobial Agents and Chemotherapy, Jg. 59, 2015, Nr. 6, S. 2971
    DOI (Open Access)
  • Higel, Fabian; Seidl, Andreas; Demelbauer, Uwe; Viertlboeck-Schudy, Margot; Koppenburg, Vera; Kronthaler, Ulrich; Sörgel, Fritz; Frieß, Wolfgang
    N-glycan PK Profiling Using a High Sensitivity nanoLCMS Work-Flow with Heavy Stable Isotope Labeled Internal Standard and Application to a Preclinical Study of an IgG1 Biopharmaceutical
    In: Pharmaceutical Research, Jg. 32, 2015, Nr. 11, S. 3649 – 3659
    DOI (Open Access)
  • Rees, Vanessa E.; Bulitta, Jürgen B.; Nation, Roger L.; Tsuji, Brian T.; Sörgel, Fritz; Landersdorfer, Cornelia B.
    Shape does matter : short high-concentration exposure minimizes resistance emergence for fluoroquinolones in Pseudomonas aeruginosa
    In: Journal of Antimicrobial Chemotherapy, Jg. 70, 2015, Nr. 3, S. 818 – 826
    DOI (Open Access)
  • Ort, Christoph; Eppler, Jonas Maria Aria; Scheidegger, Andreas; Rieckermann, Jörg; Kinzig, Martina; Sörgel, Fritz
    Challenges of surveying wastewater drug loads of small populations and generalizable aspects on optimizing monitoring design
    In: Addiction, Jg. 109, 2014, Nr. 3, S. 472 – 481
    DOI
  • Heine, Henry S.; Louie, Arnold; Adamovicz, Jeffrey J.; Amemiya, Kei; Fast, Randy L.; Miller, Lynda; Opal, Steven M.; Palardy, John; Parejo, Nicolas A.; Sörgel, Fritz; Kinzig-Schippers, Martina; Drusano, George L.
    Evaluation of imipenem for prophylaxis and therapy of yersinia pestis delivered by aerosol in a mouse model of pneumonic plague
    In: Antimicrobial Agents and Chemotherapy, Jg. 58, 2014, Nr. 6, S. 3276 – 3284
    DOI, Online Volltext (Open Access)
  • Mross, Klaus; Scheulen, Max Ernst; Strumberg, Dirk; Kuhlmann, Jan; Kanefendt, Friederike; Sörgel, Fritz; Jaehde, Ulrich; Burkholder, Iris; Moritz, Berta; Büchert, Martin
    FOLFIRI and sunitinib as first-line treatment in metastatic colorectal cancer patients with liver metastases--a CESAR phase II study including pharmacokinetic, biomarker, and imaging data
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 52, 2014, Nr. 8, S. 642 – 652
    DOI
  • Eyler, Rachel F.; Vilay, Aloun Mary Ary; Nader, Ahmed M.; Heung, Michael; Pleva, Melissa; Sowinski, Kevin M.; DePestel, Daryl D.; Sörgel, Fritz; Kinzig, Martina; Mueller, Bruce A.
    Pharmacokinetics of ertapenem in critically ill patients receiving continuous venovenous hemodialysis or hemodiafiltration
    In: Antimicrobial Agents and Chemotherapy, Jg. 58, 2014, Nr. 3, S. 1320 – 1326
    DOI, Online Volltext (Open Access)
  • Higel, Fabian; Seidl, Andreas; Demelbauer, Uwe; Sörgel, Fritz; Frieß, Wolfgang
    Small scale affinity purification and high sensitivity reversed phase nanoLC-MS N-glycan characterization of mAbs and fusion proteins
    In: mAbs, Jg. 6, 2014, Nr. 4, S. 894 – 903
    DOI (Open Access)
  • Matzneller, Peter; Krasniqi, Shaip; Kinzig, Martina; Sörgel, Fritz; Hüttner, Sven J.; Lackner, Edith; Müller, Markus M.; Zeitlinger, Markus Alexander
    Blood, tissue, and intracellular concentrations of azithromycin during and after end of therapy
    In: Antimicrobial Agents and Chemotherapy, Jg. 57, 2013, Nr. 4, S. 1736 – 1742
    DOI, Online Volltext (Open Access)
  • Goessens, Wil H. F.; Mouton, Johan W.; Ten Kate, Marian T.; Sörgel, Fritz; Kinzig, Martina; Bakker-Woudenberg, Irma A. J. M.
    The therapeutic effect of tigecycline, unlike that of ceftazidime, is not influenced by whether the 'Klebsiella pneumoniae' strain produces extended-spectrum β-lactamases in experimental pneumonia in rats
    In: Antimicrobial Agents and Chemotherapy, Jg. 57, 2013, Nr. 1, S. 643 – 646
    DOI, Online Volltext (Open Access)
  • Krasniqi, Shaip; Matzneller, Peter; Kinzig, Martina; Sörgel, Fritz; Hüttner, Sven J.; Lackner, Edith; Müller, Markus Franziskus; Zeitlinger, Markus
    Blood, Tissue, and Intracellular Concentrations of Erythromycin and Its Metabolite Anhydroerythromycin during and after Therapy
    In: Antimicrobial Agents and Chemotherapy, Jg. 56, 2012, Nr. 2, S. 1059 – 1064
    DOI
  • Djukic, Marija; Munz, Martin; Sörgel, Fritz; Holzgrabe, Ulrike; Eiffert, Helmut; Nau, Roland
    Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid
    In: Antimicrobial Agents and Chemotherapy, Jg. 56, 2012, Nr. 2, S. 979 – 988
    DOI
  • Landersdorfer, Cornelia B.; Bulitta, Jurgen B.; Kirkpatrick, Carl M.J.; Kinzig, Martina; Holzgrabe, Ulrike; Drusano, George L.; Stephan, Ulrich; Sörgel, Fritz
    Population pharmacokinetics of piperacillin at two dose levels : Influence of nonlinear pharmacokinetics on the pharmacodynamic profile
    In: Antimicrobial Agents and Chemotherapy, Jg. 56, 2012, Nr. 11, S. 5715 – 5723
    DOI
  • Elsinghorst, Paul W.; Kinzig, Martina; Rodamer, Michael; Holzgrabe, Ulrike; Sörgel, Fritz
    An LC-MS/MS procedure for the quantification of naproxen in human plasma : Development, validation, comparison with other methods, and application to a pharmacokinetic study
    In: Journal of Chromatography B, Jg. 879, 2011, Nr. 19, S. 1686 – 1696
    DOI
  • Kanefendt, F.; Lindauer, A.; Kinzig, M.; Strumberg, Dirk; Scheulen, Max Ernst; Mross, K.; Fischer, R.; Moritz, B.; Sörgel, Fritz; Jaehde, U.
    Biomarker response on exposure to sunitinib and its primary metabolite (SU12662) in metastatic colorectal cancer patients
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 49, 2011, Nr. 1, S. 88 – 90
  • Bulitta, Jürgen Bernd; Kinzig, Martina; Landersdorfer, Cornelia B.; Holzgrabe, Ulrike; Stephan, Ulrich; Sörgel, Fritz
    Comparable Population Pharmacokinetics and Pharmacodynamic Breakpoints of Cefpirome in Cystic Fibrosis Patients and Healthy Volunteers
    In: Antimicrobial Agents and Chemotherapy, Jg. 55, 2011, Nr. 6, S. 2927 – 2936
    DOI, Online Volltext (Open Access)
  • Rodamer, Michael; Elsinghorst, Paul W.; Kinzig, Martina; Gütschow, Michael; Sörgel, Fritz
    Development and validation of a liquid chromatography/tandem mass spectrometry procedure for the quantification of sunitinib (SU11248) and its active metabolite, N-desethyl sunitinib (SU12662), in human plasma : Application to an explorative study
    In: Journal of Chromatography B, Jg. 879, 2011, Nr. 11-12, S. 695 – 706
    DOI
  • Lodise, T.P.; Sorgel, F.; Melnick, D.; Mason, B.; Kinzig, M.; Drusano, G.L.
    Penetration of meropenem into epithelial lining fluid of patients with ventilator-associated pneumonia
    In: Antimicrobial Agents and Chemotherapy, Jg. 55, 2011, Nr. 4, S. 1606 – 1610
    DOI
  • Bulitta, Jürgen B.; Kinzig, Martina; Naber, Christoph; Wagenlehner, Florian M.E.; Sauber, Christian; Landersdorfer, Cornelia B.; Sörgel, Fritz; Naber, Kurt G.
    Population pharmacokinetics and penetration into prostatic, seminal, and vaginal fluid for ciprofloxacin, levofloxacin, and their combination
    In: Chemotherapy, Jg. 57, 2011, Nr. 5, S. 402 – 416
    DOI
  • Stanhope, Richard; Sörgel, Fritz; Gravel, Patricia; Pannatier Schuetz, Yannic B.; Zabransky, Markus; Muenzberg, Michael
    Bioequivalence studies of Omnitrope, the first biosimilar/rhGH follow-on protein : Two comparative phase 1 randomized studies and population pharmacokinetic analysis
    In: Journal of Clinical Pharmacology, Jg. 50, 2010, Nr. 11, S. 1339 – 1348
    DOI
  • Lee, Lois S.; Kinzig-Schippers, Martina; Nafziger, Anne N.; Ma, Lei; Sörgel, Fritz; Jones, Ronald N.; Drusano, George L.; Bertino, Joseph S.
    Comparison of 30-min and 3-h infusion regimens for imipenem/cilastatin and for meropenem evaluated by Monte Carlo simulation
    In: Diagnostic Microbiology and Infectious Disease, Jg. 68, 2010, Nr. 3, S. 251 – 258
    DOI
  • Landersdorfer, Cornelia B.; Kirkpatrick, Carl M. J.; Kinzig, Martina; Bulitta, Jürgen B.; Holzgrabe, Ulrike; Jaehde, Ulrich; Reiter, Andreas; Naber, KurtG; Rodamer, Michael; Sörgel, Fritz
    Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid
    In: British Journal of Clinical Pharmacology (BJCP), Jg. 69, 2010, Nr. 2, S. 167 – 178
    DOI
  • Gascon, P.; Fuhr, U.; Sörgel, Fritz; Kinzig-Schippers, M.; Makhson, A.; Balser, S.; Einmahl, S.; Muenzberg, M.
    Development of a new G-CSF product based on biosimilarity assessment
    In: Annals of Oncology, Jg. 21, 2010, Nr. 7, S. 1419 – 1429
    DOI (Open Access)
  • Nagy, Nadine; Freudenberger, Till; Melchior-Becker, Ariane; Röck, Katharina; Ter Braak, Michael; Jastrow, Holger; Kinzig, Martina; Lucke, Susann; Suvorava, Tatsiana; Kojda, Georg; Weber, Artur A.; Sörgel, Fritz; Levkau, Bodo; Ergün, Süleyman; Fischer, Jens W.
    Inhibition of hyaluronan synthesis accelerates murine atherosclerosis : Novel insights into the role of hyaluronan synthesis
    In: Circulation, Jg. 122, 2010, Nr. 22, S. 2313 – 2322
    DOI
  • Bulitta, Jürgen B.; Kinzig, Martina; Jakob, Verena; Holzgrabe, Ulrike; Sörgel, Fritz; Holford, Nicholas H.G.
    Nonlinear pharmacokinetics of piperacillin in healthy volunteers - implications for optimal dosage regimens
    In: British Journal of Clinical Pharmacology (BJCP), Jg. 70, 2010, Nr. 5, S. 682 – 693
    DOI
  • Nau, Roland; Sörgel, Fritz; Eiffert, Helmut
    Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections
    In: Clinical Microbiology Reviews, Jg. 23, 2010, Nr. 4, S. 858 – 883
    DOI (Open Access)
  • Sörgel, Fritz; Lerch, Helmut; Lauber, Thomas
    Physicochemical and biologic comparability of a biosimilar granulocyte colony-stimulating factor with its reference product
    In: BioDrugs, Jg. 24, 2010, Nr. 6, S. 347 – 357
    DOI
  • Bulitta, Jürgen Bernd B.; Landersdorfer, Cornelia B.; Hüttner, Sven J.; Drusano, George Louis; Kinzig, Martina; Holzgrabe, Ulrike; Stephan, Ulrich; Sörgel, Fritz
    Population pharmacokinetic comparison and pharmacodynamic breakpoints of ceftazidime in cystic fibrosis patients and healthy volunteers
    In: Antimicrobial Agents and Chemotherapy, Jg. 54, 2010, Nr. 3, S. 1275 – 1282
    DOI
  • Krege, Susanne; Kinzig-Schippers, M.; Sörgel, Fritz; Baschek, R.; Rübben, Herbert
    Absorption of intravesically applied drugs : Comparison of normal and ileal augmented rabbit bladder
    In: The Journal of Urology, Jg. 172, 2004, Nr. 5, S. 2045 – 2050
    DOI

    • Beiträge in Sammelwerken und Tagungsbänden

  • Landersdorfer, Cornelia B.; Bulitta, Jürgen B.; Nation, Roger L.; Sörgel, Fritz
    Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone
    In: Bone and Joint Infections: From Microbiology to Diagnostics and Treatment / Zimmerli, Werner (Hrsg.): Wiley, 2021
    DOI
  • Landersdorfer, Cornelia.B.; Bulitta, Jürgen.B.; Sörgel, Fritz; Landersdorfer, Cornelia B.; Bulitta, Jürgen B.
    Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone
    In: Bone and Joint Infections: From Microbiology to Diagnostics and Treatment / Zimmerli, Werner. Chichester, West Sussex: Wiley Blackwell, 2015, S. 21 – 37
    DOI