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Institut für Medizinische Mikrobiologie am Universitätsklinikum Essen

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Hufelandstr. 55
45122 Essen
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  • Universitätsprofessor/in, Institut für Medizinische Mikrobiologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Steinbach, Philine; Pastille, Eva; Kaumanns, Lara; Adamczyk, Alexandra; Sutter, Kathrin; Hansen, Wiebke; Dittmer, Ulf; Buer, Jan; Westendorf, Astrid M.; Knuschke, Torben
    Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control
    In: PLoS Pathogens Jg. 20 (2024) Nr. 1, e1011982
  • Abberger, Hanna; Hose, Matthias; Ninnemann, Anne; Menne, Christopher; Eilbrecht, Mareike; Lang, Karl S.; Matuschewski, Kai; Geffers, Robert; Herz, Josephine; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infections
    In: PLoS Pathogens Jg. 19 (2023) Nr. 11, e1011837
  • Podschwadt, Philip; Malyshkina, Anna; Windmann, Sonja; Werner, Tanja; Hansen, Wiebke; Bayer, Wibke
    A detailed analysis of F-MuLV- and SFFV-infected cells in Friend virus-infected mice reveals the contribution of both F-MuLV- and SFFV-infected cells to the interleukin-10 host response
    In: Retrovirology Jg. 19 (2022) Nr. 1, 29
  • Philipp, Svenja; Horstmann, Mareike; Hose, Matthias; Daser, Anke; Görtz, Gina-Eva; Jesenek, Christoph; Flögel, Ulrich; Hansen, Wiebke; Bechrakis, Nikolaos; Banga, Jasvinder Paul S.; Eckstein, Anja; Berchner-Pfannschmidt, Utta
    An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy
    In: Thyroid Jg. 32 (2022) Nr. 3, S. 283 - 293
  • Wilk, Camilla; Effenberg, Laura; Abberger, Hanna; Steenpass, Laura; Hansen, Wiebke; Zeschnigk, Michael; Kirschning, Carsten Jürgen; Buer, Jan; Kehrmann, Jan
    CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells
    In: Cellular Immunology Jg. 371 (2022) 104471
  • Hose, Matthias; Günther, Anne; Naser, Eyad; Schumacher, Fabian; Schönberger, Tina; Falkenstein, Julia; Papadamakis, Athanasios; Kleuser, Burkhard; Becker, Katrin Anne; Gulbins, Erich; Haimovitz-Friedman, Adriana; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    Cell-intrinsic ceramides determine T cell function during melanoma progression
    In: eLife Jg. 11 (2022) e83073
  • Pylaeva, Ekaterina; Korschunow, Georg; Spyra, Ilona; Bordbari, Sharareh; Siakaeva, Elena; Ozel, Irem; Domnich, Maksim; Squire, Anthony; Hasenberg, Anja; Thangavelu, Kruthika; Hussain, Timon; Goetz, Moritz; Lang, Karl S.; Gunzer, Matthias; Hansen, Wiebke; Buer, Jan; Bankfalvi, Agnes; Lang, Stephan; Jablonska, Jadwiga
    During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes
    In: Cell Reports Jg. 40 (2022) Nr. 7, 111171
  • Podschwadt, Philip; Malyshkina, Anna; Windmann, Sonja; Papadamakis, Athanasios; Kerkmann, Leonie; Lapuente, Dennis; Tenbusch, Matthias; Lu, Mengji; Schindler, Michael; Lang, Karl Sebastian; Hansen, Wiebke; Bayer, Wibke
    Immune suppression of vaccine-induced CD8⁺ T cell-responses by gamma retrovirus envelope is mediated by interleukin-10 producing CD4⁺ T cells
    In: Frontiers in Immunology Jg. 13 (2022) 934399
  • Beckmann, Lucia; Obst, Stefanie; Labusek, Nicole; Abberger, Hanna; Köster, Christian; Klein-Hitpaß, Ludger; Schumann, Sven; Kleinschnitz, Christoph; Hermann, Dirk M.; Felderhoff-Müser, Ursula; Bendix, Ivo; Hansen, Wiebke; Herz, Josephine
    Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain Injury
    In: Stroke Jg. 53 (2022) Nr. 2, S. 381 - 390
  • Günther, Anne; Hose, Matthias; Abberger, Hanna; Schumacher, Fabian; Veith, Ylva; Kleuser, Burkhard; Matuschewski, Kai; Lang, Karl Sebastian; Gulbins, Erich; Buer, Jan; Westendorf, Astrid M.; Hansen, Wiebke
    The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis
    In: eLife Jg. 11 (2022) e77975
  • Adamczyk, Alexandra; Pastille, Eva; Kehrmann, Jan; Vu, Vivian P.; Geffers, Robert; Wasmer, Marie-Hélène; Kasper, Stefan; Schuler, Martin; Lange, Christian; Muggli, Beat; Rau, Tilman T.; Klein, Diana; Hansen, Wiebke; Krebs, Philippe; Buer, Jan; Westendorf, Astrid
    GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer
    In: Cancer Research Jg. 81 (2021) Nr. 11, S. 2970 - 2982
  • Hansen, Wiebke; Luppus, Sina; Barthel, Romy; Chang, Dae-In; Broemstrup, Julia; Zwarg, Thomas; Shibata, Jo; Westendorf, Astrid; Buer, Jan; Scherbaum, Norbert
    Heroin-assisted treatment of heroin-addicted patients normalizes regulatory T cells but does not restore CD4⁺ T cell proliferation
    In: Addiction Biology Jg. 26 (2021) Nr. 4, S. e12998
  • Budeus, Bettina; Kibler, Artur; Brauser, Martina; Homp, Ekaterina; Bronischewski, Kevin; Ross, J. Alexander; Görgens, Andre; Weniger, Marc; Dunst, Josefine; Kreslavsky, Taras; da Conceição Castro, Symone Vitoriano; Murke, Florian; Oakes, Christopher C.; Rusch, Peter; Andrikos, Dimitrios; Kern, Peter; Köninger, Angela; Lindemann, Monika; Johansson, Patricia; Hansen, Wiebke; Lundell, Anna-Carin; Rudin, Anna; Dürig, Jan; Giebel, Bernd; Hoffmann, Daniel; Küppers, Ralf; Seifert, Marc
    Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamics
    In: The Journal of Immunology (JI) Jg. 206 (2021) Nr. 12, S. 2839 - 2851
  • Ngo Thi Phuong, Nhi; Palmieri, Vittoria; Adamczyk, Alexandra; Klopfleisch, Robert; Langhorst, Jost; Hansen, Wiebke; Westendorf, Astrid; Pastille, Eva
    IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute Colitis
    In: Frontiers in Immunology Jg. 12 (2021) 669787
  • Palmieri, Vittoria; Ebel, Jana-Fabienne; Ngo Thi Phuong, Nhi; Klopfleisch, Robert; Vu, Vivian Pham; Adamczyk, Alexandra; Zöller, Julia; Riedel, Christian; Buer, Jan; Krebs, Philippe; Hansen, Wiebke; Pastille, Eva; Westendorf, Astrid M.
    Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity
    In: Mucosal Immunology Jg. 14 (2021) Nr. 4, S. 923 - 936
  • Abberger, Hanna; Barthel, Romy; Bahr, Jasmin; Thiel, Jacqueline; Luppus, Sina; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    Neuropilin-1 is expressed on highly activated cd4+ effector t cells and dysfunctional cd4+ conventional t cells from naive mice
    In: The Journal of Immunology (JI) Jg. 207 (2021) Nr. 5, S. 1288 - 1297
  • Zöller, Julia; Ebel, Jana-Fabienne; Khairnar, Vishal; Schmitt, Verena; Klopfleisch, Robert; Meiners, Jana; Seiffart, Virginia; Hansen, Wiebke; Buer, Jan; Singer, Bernhard B.; Lang, Karl S.; Westendorf, Astrid
    CEACAM1 regulates CD8⁺ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis
    In: Gut Microbes Jg. 11 (2020) Nr. 6, S. 1790 - 1805
  • Liedtke, Katarina; Alter, Christina; Günther, Anne; Hövelmeyer, Nadine; Klopfleisch, Robert; Naumann, Ronald; Wunderlich, F Thomas; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    Endogenous CD83 Expression in CD4⁺ Conventional T Cells Controls Inflammatory Immune Responses
    In: The Journal of Immunology (JI) Jg. 204 (2020) Nr. 12, S. 3217 - 3226
  • Hansen, Wiebke
    Malaria - quo vadis? : Neue Erkenntnisse zur Therapie, Impfstoffentwicklung und Reaktion unseres Immunsystems
    In: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 28 - 37
  • Heße, Carolin; Kollenda, Sebastian; Rotan, Olga; Pastille, Eva; Adamczyk, Alexandra; Wenzek, Christina; Hansen, Wiebke; Epple, Matthias; Buer, Jan; Westendorf, Astrid; Knuschke, Torben
    A tumor-peptide–based nanoparticle vaccine elicits efficient tumor growth control in antitumor immunotherapy
    In: Molecular Cancer Therapeutics Jg. 18 (2019) Nr. 6, S. 1069 - 1080
  • Verhasselt, Hedda Luise; Radke, Julia; Schmidt, Dirk; Killengray, David; Scharmann, Ulrike; Rickerts, Volker; Hansen, Wiebke; Seidel, Danila; Falces-Romero, Iker; Buer, Jan; Rath, Peter-Michael; Steinmann, Jörg
    Comparison of genotyping methods for Cunninghamella bertholletiae
    In: Mycoses Jg. 62 (2019) Nr. 6, S. 519 - 525
  • Plöhn, Svenja; Hose, Matthias; Schlüter, Anke; Michel, Lars; Diaz-Cano, Salvador; Hendgen-Cotta, Ulrike B.; Banga, Jasvinder Paul; Bechrakis, Nikolaos E.; Hansen, Wiebke; Eckstein, Anja; Berchner-Pfannschmidt, Utta
    Fingolimod Improves the Outcome of Experimental Graves' Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone Receptor
    In: Thyroid Jg. 29 (2019) Nr. 9, S. 1286 - 1301
  • Schulte-Mecklenbeck, Andreas; Kleffner, Ilka; Beuker, Carolin; Wirth, Timo; Hartwig, Marvin; Schmidt-Pogoda, Antje; Klotz, Luisa; Hansen, Wiebke; Wiendl, Heinz S.; Meuth, Sven G.; Groß, Catharina C.; Minnerup, Jens
    Immunophenotyping of cerebrospinal fluid cells in ischaemic stroke
    In: European Journal of Neurology Jg. 26 (2019) Nr. 6, S. 919 - 926
  • Ploehn, S.; Hose, M.; Schlüter, Anke; Michel, L.; Diaz-Cano, S.; Banga, P.; Hansen, Wiebke; Eckstein, Anja; Berchner-Pfannschmidt, Utta
    Immunotherapy with fingolimod improves outcome of experimental Graves disease and associated orbitopathy by modulating autoimmune response to thyroid stimulating hormone receptor
    In: Investigative Ophthalmology & Visual Science, IOVS Jg. 60 (2019) Nr. 9,
  • Meiners, Jana; Palmieri, Vittoria; Klopfleisch, Robert; Ebel, Jana-Fabienne; Japtok, Lukasz; Schumacher, Fabian; Mohamud Yusuf, Ayan; Becker, Katrin A.; Zöller, Julia; Hose, Matthias; Kleuser, Burkhard; Hermann, Dirk M.; Kolesnick, Richard N.; Buer, Jan; Hansen, Wiebke; Westendorf, Astrid
    Intestinal acid sphingomyelinase protects from severe pathogen-driven colitis
    In: Frontiers in Immunology Jg. 10 (2019) 1386
  • Thiel, Jacqueline; Alter, Christina; Luppus, Sina; Eckstein, Anja; Tan, Susanne; Führer, Dagmar; Pastille, Eva; Westendorf, Astrid; Buer, Jan; Hansen, Wiebke
    MicroRNA-183 and microRNA-96 are associated with autoimmune responses by regulating T cell activation
    In: Journal of Autoimmunity Jg. 96 (2019) S. 94 - 103
  • Hose, Matthias; Günther, Anne; Abberger, Hanna; Begum, Salina; Korencak, Marek; Becker, Katrin A.; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    T cell-specific overexpression of acid sphingomyelinase results in elevated T cell activation and reduced parasitemia during Plasmodium yoelii infection
    In: Frontiers in Immunology Jg. 10 (2019) S. 1225
  • Pastille, Eva; Wasmer, Marie-Hélène; Adamczyk, Alexandra; Vu, Vivian P.; Mager, Lukas F.; Phuong, Nhi Ngo Thi; Palmieri, Vittoria; Simillion, Cedric; Hansen, Wiebke; Kasper, Stefan; Schuler, Martin; Muggli, Beat; McCoy, Kathy D.; Buer, Jan; Zlobec, Inti; Westendorf, Astrid; Krebs, Philippe
    The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer
    In: Mucosal Immunology Jg. 12 (2019) Nr. 4, S. 990 - 1003
  • Plöhn, Svenja; Edelmann, Bärbel; Japtok, Lukasz; He, Xingxuan; Hose, Matthias; Hansen, Wiebke; Schuchman, Edward H.; Eckstein, Anja; Berchner-Pfannschmidt, Utta
    CD40 Enhances Sphingolipids in Orbital Fibroblasts : Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' Orbitopathy
    In: Investigative Ophthalmology & Visual Science, IOVS Jg. 59 (2018) Nr. 13, S. 5391 - 5397
  • Knuschke, Torben; Rotan, Olga; Bayer, Wibke; Kollenda, Sebastian; Dickow, Julia; Sutter, Kathrin; Hansen, Wiebke; Dittmer, Ulf; Lang, Karl S.; Epple, Matthias; Buer, Jan; Westendorf, Astrid
    Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral Infection
    In: Frontiers in Immunology Jg. 9 (2018) 614
  • Herz, Josephine; Köster, Christian; Reinboth, Barbara S.; Dzietko, Mark; Hansen, Wiebke; Sabir, Hemmen; van Velthoven, Cindy; Bendix, Ivo; Felderhoff-Müser, Ursula
    Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injury
    In: Brain, Behavior and Immunity Jg. 70 (2018) S. 118 - 130
  • Herz, Josephine; Köster, Christian; Crasmöller, Marius; Abberger, Hanna; Hansen, Wiebke; Felderhoff-Müser, Ursula; Bendix, Ivo
    Peripheral T cell depletion by FTY720 exacerbates hypoxic-ischemic brain injury in neonatal mice
    In: Frontiers in Immunology Jg. 9 (2018) S. 1696
  • Batzke, Katharina; Büchel, Gabriele; Hansen, Wiebke; Schramm, Alexander
    TrkB-Target Galectin-1 Impairs Immune Activation and Radiation Responses in Neuroblastoma : Implications for Tumour Therapy
    In: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 3, S. 718
  • Ueffing, Kristina; Abberger, Hanna; Westendorf, Astrid; Matuschewski, Kai; Buer, Jan; Hansen, Wiebke
    Conventional CD11chigh Dendritic Cells Are Important for T Cell Priming during the Initial Phase of Plasmodium yoelii Infection, but Are Dispensable at Later Time Points
    In: Frontiers in Immunology Jg. 8 (2017) 1333
  • Loevenich, Katharina; Ueffing, Kristina; Abel, Simone; Hose, Matthias; Matuschewski, Kai; Westendorf, Astrid; Buer, Jan; Hansen, Wiebke
    DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4+IL-10+ Regulatory T Cells during Plasmodium yoelii Infection
    In: Frontiers in Immunology Jg. 8 (2017) 152
  • Adamczyk, Alexandra; Gageik, Daniel; Frede, Annika; Pastille, Eva; Hansen, Wiebke; Rueffer, Andreas; Buer, Jan; Büning, Jürgen; Langhorst, Jost; Westendorf, Astrid
    Differential expression of GPR15 on T cells during ulcerative colitis
    In: JCI Insight Jg. 2 (2017) Nr. 8, e90585
  • Westendorf, Astrid; Skibbe, Kathrin; Adamczyk, Alexandra; Buer, Jan; Geffers, Robert; Hansen, Wiebke; Pastille, Eva; Jendrossek, Verena
    Hypoxia enhances immunosuppression by inhibiting CD4+ Effector T cell function and promoting treg activity
    In: Cellular Physiology and Biochemistry Jg. 41 (2017) Nr. 4, S. 1271 - 1284
  • Pastille, Eva; Frede, Annika; McSorley, Henry J.; Gräb, Jessica; Adamczyk, Alexandra; Kollenda, Sebastian; Hansen, Wiebke; Epple, Matthias; Buer, Jan; Maizels, Rick M.; Klopfleisch, Robert; Westendorf, Astrid
    Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer
    In: PLoS Pathogens Jg. 13 (2017) Nr. 9, e1006649
  • Frede, Annika; Neuhaus, Bernhard; Knuschke, Torben; Wadwa, Munisch; Kollenda, Sebastian; Klopfleisch, Robert; Hansen, Wiebke; Buer, Jan; Bruder, Dunja; Epple, Matthias; Westendorf, Astrid
    Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation
    In: Nanomedicine: Nanotechnology, Biology, and Medicine Jg. 13 (2017) Nr. 8, S. 2395 - 2403
  • Barthel, R.; Buer, Jan; Hansen, Wiebke
    Neuropilin-1 and its role in intratumoral CD4+T cell function
    In: European Journal of Immunology Jg. 47 (2017) Nr. Suppl. 2 SI, S. 266 Abstract P361
  • Smirnov, Anna; Pohlmann, Stephanie; Nehring, Melanie; Ali, Shafaqat; Mann-Nüttel, Ritu; Scheu, Stefanie; Antoni, Anne-Charlotte; Hansen, Wiebke; Büettner, Manuela; Gardiasch, Miriam J.; Westendorf, Astrid; Wirsdörfer, Florian; Pastille, Eva; Dudda, Marcel; Flohe, Stefanie
    Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression
    In: Frontiers in Immunology Jg. 8 (2017) 1622
  • Knuschke, Torben; Rotan, Olga; Bayer, Wiebke; Sokolova, Viktoriya; Hansen, Wiebke; Sparwasser, Tim; Dittmer, Ulf; Epple, Matthias; Buer, Jan; Westendorf, Astrid
    Combination of nanoparticle‑based therapeutic vaccination and transient ablation of regulatory T cells enhances anti‑viral immunity during chronic retroviral infection
    In: Retrovirology Jg. 13 (2016) 24
  • Berchner-Pfannschmidt, Utta; Banga, J. Paul; Eckstein, Anja; Hansen, Wiebke; Noble, Alistair; Horstmann, Mareike; Görtz, Gina-Eva; Edelmann, Bärbel; Diaz-Cano, Salvador; Moshkelgosha, Sajad
    Comparative assessment of female mouse model of Graves' orbitopathy under different environments, accompanied by proinflammatory cytokine and T-cell responses to thyrotropin hormone receptor antigen
    In: Endocrinology Jg. 157 (2016) Nr. 4, S. 1673 - 1682
  • Gamrad, Lisa; Rehbock, Christoph; Westendorf, Astrid; Buer, Jan; Barcikowski, Stephan; Hansen, Wiebke
    Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugates
    In: Scientific Reports Jg. 6 (2016) 28709
  • Serdar, Meray; Herz, Josephine; Kempe, Karina; Lumpe, Katharina; Reinboth, Barbara S.; Sizonenko, Stéphane V.; Hou, Xinlin; Herrmann, Ralf; Hadamitzky, Martin; Heumann, Rolf; Hansen, Wiebke; Sifringer, Marco; van de Looij, Yohan; Felderhoff-Müser, Ursula; Bendix, Ivo
    Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia
    In: Brain, Behavior and Immunity Jg. 52 (2016) S. 106 - 119
  • Wadwa, Munisch-Kumar; Klopfleisch, R; Adamczyk, A; Frede, A; Pastille, Eva; Mahnke, K; Hansen, Wiebke; Geffers, R; Lang, Karl S.; Buer, Jan; Büning, J; Westendorf, Astrid
    IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sites
    In: Mucosal Immunology Jg. 9 (2016) Nr. 5, S. 1263 - 1277
  • Büchel, Gabriele; Schulte, Johannes; Harrison, Luke; Batzke, Katharina; Schüller, Ulrich; Hansen, Wiebke; Schramm, Alexander
    Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma
    In: OncoImmunology Jg. 5 (2016) Nr. 5, e1131378
  • Abel, Simone; Hansen, Wiebke; Buer, Jan; Westendorf, Astrid; Kehrmann, Jan; Matuschewski, Kai; Hose, Matthias; Hutzler, Marina; Tatura, Roman; Ueffing, Kristina
    Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cells
    In: Immunology Jg. 148 (2016) Nr. 2, S. 197 - 205
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Pastille, Eva; Hansen, Wiebke; Flohe, Stefanie
    Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice
    In: Clinical Science Jg. 128 (2015) Nr. 11, S. 825 - 838
  • Niezold, Thomas; Storcksdieck Genannt Bonsmann, Michael; Maaske, André; Temchura, Vladimir; Heinecke, Vanessa; Hannaman, Drew; Buer, Jan; Ehrhardt, Christina; Hansen, Wiebke; Überla, Klaus; Tenbusch, Matthias
    DNA vaccines encoding DEC205-targeted antigens : immunity or tolerance?
    In: Immunology Jg. 145 (2015) Nr. 4, S. 519 - 533
  • Seiffart, Virginia; Zoeller, Julia; Klopfleisch, Robert; Wadwa, Munisch-Kumar; Hansen, Wiebke; Buer, Jan; Riedel, Christian; Westendorf, Astrid
    IL10-Deficiency in CD4⁺ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis
    In: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 4, S. 1259 - 1273
  • Tatura, Roman; Zeschnigk, Michael; Hansen, Wiebke; Steinmann, Jörg; Goncalves Vidigal, Pedrina; Hutzler, Marina; Pastille, Eva; Westendorf, Astrid; Buer, Jan; Kehrmann, Jan
    Relevance of Foxp3+ regulatory T cells for early and late phases of murine sepsis
    In: Immunology Jg. 146 (2015) Nr. 1, S. 144 - 156
  • Herz, Josephine; Hagen, Sabine I; Bergmüller, Eileen; Sabellek, Pascal; Göthert, Joachim Rudolf; Buer, Jan; Hansen, Wiebke; Hermann, Dirk M.; Döppner, Thorsten R.
    Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responses
    In: Neurobiology of Disease Jg. 62 (2014) S. 456 - 468
  • Knuschke, Torben; Bayer, Wibke; Rotan, Olga; Sokolova, Viktoriya; Wadwa, Munisch; Kirschning, Carsten Jürgen; Hansen, Wiebke; Sparwasser, T.; Dittmer, Ulf; Epple, Matthias; Buer, Jan; Westendorf, Astrid
    Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection
    In: Nanomedicine: Nanotechnology, Biology, and Medicine Jg. 10 (2014) Nr. 8, S. 1787 - 1798
  • Jost, Nils H; Abel, Simone; Hutzler, Marina; Sparwasser, Tim; Zimmermann, Albert; Roers, Axel; Müller, Werner; Klopfleisch, Robert; Hengel, Hartmut; Westendorf, Astrid; Buer, Jan; Hansen, Wiebke
    Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune response
    In: Immunology and Cell Biology Jg. 92 (2014) Nr. 10, S. 860 - 871
  • Pastille, Eva; Bardini, Katrin; Fleissner, Diana; Adamczyk, Alexandra; Frede, Annika; Wadwa, Munisch; Smolinski, Dorthe von; Kasper, Stefan; Sparwasser, Tim; Gruber, Achim D.; Schuler, Martin; Sakaguchi, Shimon; Roers, Axel; Müller, Werner; Hansen, Wiebke; Buer, Jan; Westendorf, Astrid
    Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer
    In: Cancer Research Jg. 74 (2014) Nr. 16, S. 4258 - 4269
  • Knuschke, Torben; Sokolova, Viktoriya; Rotan, Olga; Wadwa, Munisch; Tenbusch, Matthias; Hansen, Wiebke; Staeheli, Peter; Epple, Matthias; Buer, Jan; Westendorf, Astrid M.
    Immunization with biodegradable nanoparticles efficiently induces cellular immunity and protects against influenza virus infection
    In: The Journal of Immunology (JI) Jg. 190 (2013) Nr. 12, S. 6221 - 6229
  • Hansen, Wiebke
    Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
    In: OncoImmunology Jg. 2 (2013) Nr. 2, e23039
  • Helfrich, Iris; Hansen, Wiebke; Hutzler, Marina; Sakaguchi, S.; Albert, J.; Stockmann, C.; Buer, Jan; Schadendorf, Dirk
    Neuropilin-1 Deficiency on CD4+Foxp3+Regulatory T Cells Modulates Tumor Angiogenesis and Impaires Tumor Growth in Melanoma
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 11 (2013) Nr. Suppl. S7, S. 30
  • Hutzler, Marina; Helfrich, Iris; Schadendorf, Dirk; Buer, Jan; Hansen, Wiebke
    Neuropilin-1 is a key mediator of VEGF-dependent Treg migration to tumors
    In: International Journal of Molecular Medicine Jg. 32 (2013) Nr. Suppl. 1, S. S36
  • Jeron, Andreas; Hansen, Wiebke; Ewert, Franziska; Buer, Jan; Geffers, Robert; Bruder, Dunja
    ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells
    In: BMC Genomics Jg. 13 (2012) Nr. 1, S. 705
  • Veldman, C.; Pahl, A.; Beissert, S.; Hansen, Wiebke; Buer, Jan; Dieckmann, D.; Schuler, G.; Hertl, M.
    Correction: Inhibition of the transcription factor Foxp3 converts desmoglein 3-specific type 1 regulatory T cells into Th2-like cells
    In: The Journal of Immunology (JI) Jg. 189 (2012) Nr. 7, S. 3779 - 3779
  • Hansen, Wiebke; Hutzler, Marina; Abel, Simone; Alter, Christina; Stockmann, Christian; Kliche, Stefanie; Albert, Juliane; Sparwasser, Tim; Sakaguchi, Shimon; Westendorf, Astrid; Schadendorf, Dirk; Buer, Jan; Helfrich, Iris
    Neuropilin 1 deficiency on CD4⁺Foxp3⁺ regulatory T cells impairs mouse melanoma growth
    In: Journal of Experimental Medicine (JEM) Jg. 209 (2012) Nr. 11, S. 2001 - 2016
  • Hutzler, Marina; Hansen, Wiebke
    Neuropilin-1 interferes with CD4(+) T cell responses
    In: Immunology Jg. 137 (2012) Nr. Suppl. 1, S. 256 - 256
  • Riß, Gina-Lucia; Chang, Dae-In; Wevers, Carolin; Westendorf, Astrid; Buer, Jan; Scherbaum, Norbert; Hansen, Wiebke
    Opioid maintenance therapy restores CD4⁺ T cell function by normalizing CD4⁺CD25hⁱgh regulatory T cell frequencies in heroin user
    In: Brain, Behavior and Immunity Jg. 26 (2012) Nr. 6, S. 972 - 978
  • Abel, Simone; Lückheide, Nadja; Westendorf, Astrid; Geffers, Robert; Roers, Axel; Müller, Werner; Sparwasser, Tim; Matuschewski, Kai; Buer, Jan; Hansen, Wiebke
    Strong impact of CD4 ⁺Foxp3 ⁺ regulatory T cells and limited effect of T cell-derived IL-10 on pathogen clearance during Plasmodium yoelii infection
    In: The Journal of Immunology (JI) Jg. 188 (2012) Nr. 11, S. 5467 - 5477
  • Jost, N.; Roers, A.; Sparwasser, T.; Muller, W.; Buer, Jan; Hansen, Wiebke
    The role of regulatory T cells during mCMV infections
    In: Immunology Jg. 137 (2012) Nr. Suppl. 1, S. 417 - 417
  • Fleissner, Diana; Frede, Annika; Knott, Markus; Knuschke, Torben; Geffers, Robert; Hansen, Wiebke; Dobos, Gustav; Langhorst, Jost; Buer, Jan; Westendorf, Astrid
    Generation and function of immunosuppressive human and murine CD8⁺ T cells by transforming growth factor-β and retinoic acid
    In: Immunology Jg. 134 (2011) Nr. 1, S. 82 - 92
  • Fleissner, D; Loser, K; Hansen, Wiebke; Dissemond, Joachim; Körber, Andreas; Beissert, S; Buer, Jan; Westendorf, Astrid
    In vitro induced CD8+ regulatory T cells inhibit skin inflammation
    In: European Journal of Microbiology and Immunology Jg. 1 (2011) Nr. 3, S. 208 - 214
  • Abel, Simone; Matuschewski, K.; Buer, Jan; Hansen, Wiebke
    The course of Plasmodium yoelii-infection is affected by CD4(+)Foxp3(+) regulatory T-cells
    In: International Journal of Medical Microbiology (IJMM) Jg. 301 (2011) Nr. Suppl. 47, S. 49
  • Hansen, Wiebke; Westendorf, Astrid; Toepfer, Tanja; Mauel, Susanne; Geffers, Robert; Gruber, Achim D.; Buer, Jan
    Inflammation in vivo is modulated by gpr83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells
    In: Genes and Immunity Jg. 11 (2010) Nr. 4, S. 357 - 361
  • Fleissner, Diana; Hansen, Wiebke; Geffers, Robert; Buer, Jan; Westendorf, Astrid
    Local induction of immunosuppressive CD⁸ T cells in the gut-associated lymphoid tissues
    In: PLoS ONE Jg. 5 (2010) Nr. 10, e15373
  • Bendix, Ivo; Pfüller, Caspar F.; Leuenberger, Tina; Glezeva, Nadezhda; Siffrin, Volker; Müller, Yasmin; Prozorovski, Timour; Hansen, Wiebke; Topphoff, Ulf Schulze; Loddenkemper, Christoph; Zipp, Frauke; Waiczies, Sonia
    MAPK3 deficiency drives autoimmunity via DC arming
    In: European Journal of Immunology Jg. 40 (2010) Nr. 5, S. 1486 - 1495
  • Westendorf, Astrid; Fleissner, Diana; Hansen, Wiebke; Buer, Jan
    T cells, dendritic cells and epithelial cells in intestinal homeostasis
    In: International Journal of Medical Microbiology (IJMM) Jg. 300 (2010) Nr. 1, S. 11 - 18
  • Westendorf, Astrid; Fleissner, D.; Groebe, L.; Jung, S.; Gruber, A.D.; Hansen, Wiebke; Buer, Jan
    CD4⁺Foxp3⁺ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cells
    In: Gut Jg. 58 (2009) Nr. 2, S. 211 - 219
  • Reinwald, Simone; Wiethe, Carsten; Westendorf, Astrid; Breloer, Minka; Probst-Kepper, Michael; Fleischer, Bernhard; Steinkasserer, Alexander; Buer, Jan; Hansen, Wiebke
    CD83 expression in CD4⁺ T cells modulates inflammation and autoimmunity
    In: The Journal of Immunology (JI) Jg. 180 (2008) Nr. 9, S. 5890 - 5897
  • Hansen, Wiebke; Westendorf, Astrid; Reinwald, Simone; Bruder, Dunja; Deppenmeier, Stefanie; Groebe, Lothar; Probst-Kepper, Michael; Gruber, Achim D.; Geffers, Robert; Buer, Jan
    Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3⁻CD25⁻ regulatory T cells
    In: The Journal of Immunology (JI) Jg. 179 (2007) Nr. 12, S. 8059 - 8068
  • Ukena, Sya N.; Singh, Anurag; Dringenberg, Ulrike; Engelhardt, Regina; Seidler, Ursula; Hansen, Wiebke; Bleich, André; Bruder, Dunja; Franzke, Anke; Rogler, Gerhard; Suerbaum, Sebastian; Buer, Jan; Gunzer, Florian; Westendorf, Astrid
    Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity
    In: PLoS ONE Jg. 2 (2007) Nr. 12, e1308
  • Westendorf, Astrid; Fleissner, Diana; Deppenmeier, Stefanie; Gruber, Achim Dieter; Bruder, Dunja; Hansen, Wiebke; Liblau, Roland; Buer, Jan
    Autoimmune-Mediated Intestinal Inflammation-Impact and Regulation of Antigen-Specific CD8⁺ T Cells
    In: Gastroenterology Jg. 131 (2006) Nr. 2, S. 510 - 524
  • De Buhr, Maike F.; Mähler, Michael; Geffers, Robert; Hansen, Wiebke; Westendorf, Astrid; Lauber, Jörg; Buer, Jan; Schlegelberger, Brigitte; Hedrich, Hans J.; Bleich, Andre
    Cd14, Gbp1, and Pla2g2a : Three major candidate genes for experimental IBD identified by combining QTL and microarray analyses
    In: Physiological Genomics Jg. 25 (2006) Nr. 3, S. 426 - 434
  • Hansen, Wiebke; Loser, Karin; Westendorf, Astrid; Bruder, Dunja; Pfoertner, Susanne; Siewert, Christiane; Huehn, Jochen; Beissert, Stefan; Buer, Jan
    G protein-coupled receptor 83 overexpression in naive CD4 ⁺CD25⁻ T cells leads to the induction of Foxp3⁺ regulatory T cells in vivo
    In: The Journal of Immunology (JI) Jg. 177 (2006) Nr. 1, S. 209 - 215
  • Pfoertner, Susanne; Jeron, Andreas; Probst-Kepper, Michael; Guzman, Carlos A.; Hansen, Wiebke; Westendorf, Astrid; Toepfer, Tanja; Schrader, Andres J.; Franzke, Anke; Buer, Jan; Geffers, Robert
    Signatures of human regulatory T cells : An encounter with old friends and new players
    In: Genome Biology Jg. 7 (2006) Nr. 7, R54
  • Westendorf, Astrid; Templin, M.; Geffers, R.; Deppenmeier, S.; Gruber, A.D.; Probst-Kepper, Michael; Hansen, Wiebke; Liblau, R.S.; Gunzer, F.; Bruder, D.; Buer, Jan
    CD4⁺ T cell mediated intestinal immunity : Chronic inflammation versus immune regulation
    In: Gut Jg. 54 (2005) Nr. 1, S. 60 - 69
  • Goelden, Ulrike; Pfoertner, Susanne; Hansen, Wiebke; Toepfer, Tanja; Von Knobloch, Rolf; Hofmann, Rainer; Buer, Jan; Schrader, Andres Jan
    Expression and functional influence of cellular retinoic acid-binding protein II in renal cell carcinoma
    In: Urologia Internationalis Jg. 75 (2005) Nr. 3, S. 269 - 276
  • Hansen, Wiebke; Grabenhorst, Eckart; Nimtz, Manfred; Müller, Katja; Conradt, Harald S.; Wirth, Manfred
    Generation of serum-stabilized retroviruses : Reduction of α1,3gal-epitope synthesis in a murine NIH3T3-derived packaging cell line by expression of chimeric glycosyltransferases
    In: Metabolic Engineering Jg. 7 (2005) Nr. 3, S. 221 - 228
  • Loser, K.; Hansen, Wiebke; Apelt, J.; Balkow, S.; Buer, Jan; Beissert, S.
    In vitro-generated regulatory T cells induced by Foxp3-retrovirus infection control murine contact allergy and systemic autoimmunity
    In: Gene Therapy Jg. 12 (2005) Nr. 17, S. 1294 - 1304
  • Buer, Jan; Westendorf, Astrid; Zeng, An-Ping; He, Feng; Hansen, Wiebke; Probst-Kepper, Michael
    Mechanisms of central and peripheral T-cell tolerance : An update
    In: Transfusion Medicine and Hemotherapy Jg. 32 (2005) Nr. 6, S. 384 - 399
  • Bruder, Dunja; Westendorf, Astrid; Hansen, Wiebke; Prettin, Silvia; Gruber, Achim D.; Qian, Yingjie; Von Boehmer, Harald; Mahnke, Karsten; Buer, Jan
    On the edge of autoimmunity : T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes
    In: Diabetes Jg. 54 (2005) Nr. 12, S. 3395 - 3401
  • Ukena, Sya N.; Westendorf, Astrid; Hansen, Wiebke; Rohde, Manfred; Geffers, Robert; Coldewey, Sina; Suerbaum, Sebastian; Buer, Jan; Gunzer, Florian
    The host response to the probiotic Escherichia coli strain Nissle 1917 : Specific up-regulation of the proinflammatory chemokine MCP-1
    In: BMC Medical Genetics Jg. 6 (2005) 43
  • Bruder, Dunja; Probst-Kepper, Michael; Westendorf, Astrid; Geffers, Robert; Beissert, Stefan; Loser, Karin; von Boehmer, Harald; Buer, Jan; Hansen, Wiebke; Westendorf, Astrid
    Frontline: Neuropilin-1 : A surface marker of regulatory T cells
    In: European Journal of Immunology Jg. 34 (2004) Nr. 3, S. 623 - 630
  • Hansen, Wiebke; Buer, Jan
    Role of Regulatory T Cells for the Outcome of Allo- and Autoimmune Responses
    In: Transfusion Medicine and Hemotherapy Jg. 31 (2004) Nr. 5, S. 322 - 331
  • Franzke, Anke; Piao, Wenji; Lauber, Jörg; Gatzlaff, Patricia; Könecke, Christian; Hansen, Wiebke; Schmitt-Thomsen, Angela; Hertenstein, Bernd; Buer, Jan; Ganser, Arnold
    G-CSF as immune regulator in T cells expressing the G-CSF receptor : Implications for transplantation and autoimmune diseases
    In: Blood Jg. 102 (2003) Nr. 2, S. 734 - 739
  • Matussek, Andreas; Lauber, Joerg; Bergau, Anna; Hansen, Wiebke; Rohde, Manfred; Dittmar, Kurt E. J.; Gunzer, Matthias; Mengel, Michael; Gatzlaff, Patricia; Hartmann, Maike; Buer, Jan; Gunzer, Florian
    Molecular and functional analysis of Shiga toxin-induced response patterns in human vascular endothelial cells
    In: Blood Jg. 102 (2003) Nr. 4, S. 1323 - 1332
  • Miller, B. T.; Hansen, Wiebke; Manus, S.; Luyken, Richard J.; Lorke, Axel; Kotthaus, Jörg P.; Medeiros-Ribeiro, G.; Petroff, Pierre M.
    Few-electron ground states of charge-tunable self-assembled quantum dots
    In: Physical Review B: Condensed matter and materials physics Jg. 56 (1997) Nr. 11, S. 6764 - 6769
  • Abstracts

  • Hose, Matthias; Guenther, Anne; Schumacher, Fabian; Hansen, Wiebke;
    Cell-intrinsic ceramide concentrations determine CD8+ T cell function in vitro and in vivo
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 49
  • Gausmann, Nadine; Haupeltshofer, Steffen; Casas, Ana I.; Kleinschnitz, Christoph; Hansen, Wiebke;
    Impact of plasma kallikrein on CD4+T cell function
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France, S. 66
  • Falkenstein, Julia; Buer, Jan; Lang, Karl S.; Hansen, Wiebke;
    Splenic Macrophages are Important for Pathogen Clearance and Induction of T cell Responses during Malaria
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 16
  • Günther, Anne; Hose, Matthias; Hansen, Wiebke;
    The Acid Ceramidase/Ceramide Axis : a Potential New Target for Malaria Therapy
    Joint Conference of the Société Française d’Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26–29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 336
  • Beckmann, Lucia; Obst, Stefanie; Abberger, Hanna; Koester, Christian; Kaminski, Nicole; Kleinschnitz, Christoph; Hermann, Dirk M.; Felderhoff-Müser, Ursula; Bendix, Ivo; Hansen, Wiebke; Herz, Josephine;
    Regulatory T cells contribute to sexual dimorphism in neonatal hypoxic-ischemic brain injury
    4th Congress of Joint European Neonatal Societies: Brain, Development and Imaging; 14–18 September 2021; Virtual, Online,
    In: Pediatric Research Jg. 90 (2021) Nr. Suppl. 1, S. 3
  • Seiffart, Virginia; Hemmler-Roloff, M.; Juszczak, P.; Riedel, C. U.; Buer, Jan; Hansen, Wiebke; Westendorf, Astrid;
    Impact of IL-10 in Citrobacter rodentium induced intestinal inflammation
    65th Annual Meeting of the German Society for Hygiene and Microbiology (DGHM), 22.-25.09.2013, Rostock,
    In: International Journal of Medical Microbiology (IJMM) Jg. 303 (2013) Nr. Suppl. 1, S. 35 - 35
  • Buer, Jan; Hutzler, Marina; Helfrich, Iris; Schadendorf, Dirk; Hansen, Wiebke
    Neuropilin-1 mediates infiltration of regulatory T cells into tumors favoring immune escape
    In: European Journal of Immunology Jg. 190 (2013) S. P2063
  • Beiträge in Sammelwerken und Tagungsbänden

  • Barcikowski, Stephan; Gamrad, Lisa; Rehbock, Christoph; Hansen, Wiebke
    Stabilizer-free gold nanoparticle bioconjugates as efficient transfection agents in regulatory T cells
    In: Annual Conference of the German Society for Biomaterials 2016: abstracts / Jahrestagung der Deutschen Gesellschaft für Biomaterialien ; Annual Conference of the German Society for Biomaterials ; Aachen, 29.09.-01.10.2016; Stiesch, Meike / Barcikowski, Stephan; Jockenhövel, Stefan; Sternberg, Katrin (Hrsg.) 2016, S. S20
  • Westendorf, Astrid; Bruder, Dunja; Hansen, Wiebke; Buer, Jan
    Intestinal epithelial antigen induces CD4⁺ T cells with regulatory phenotype in a transgenic autoimmune mouse model
    In: Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways / International Symposium Inflammatory Bowel Disease: Research Drives Clinics Genetics, Barrier Function, Immunological and Microbial Pathways, 01.-03.09.2005, Münster / Domschke, Wolfram W. (Hrsg.) 2006, S. 401 - 406
  • Bücher/Sammelwerke/Tagungsbände

  • Hansen, Wiebke
    Charakterisierung und Modulation regulatorischer T-Zellfunktion
    Duisburg, Essen (2010) 1 CD-ROM