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Institut für Medizinische Mikrobiologie am Universitätsklinikum Essen
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Hufelandstr. 55
45122 Essen
45122 Essen
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Universitätsprofessor/in, Institut für Medizinische Mikrobiologie
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Prorektorin, Rektorat
Prorektorin für Forschung und wissenschaftlichen Nachwuchs
AnschriftUniversitätsstr. 2, 45141 Essen
Postanschrift: Forsthausweg 2,LG502,47057 DuisburgRaumT01 S06 B34Telefon -
Beratendes Mitglied, Kommission für Forschung, wissenschaftlichen Nachwuchs und Wissenstransfer
Aktuelle Veranstaltungen
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WiSe 2025
Vergangene Veranstaltungen (max. 10)
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SoSe 2025
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WiSe 2024
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SoSe 2024
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WiSe 2023
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SoSe 2023
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WiSe 2022
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SoSe 2022
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WiSe 2021
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SoSe 2021
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WiSe 2020
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Influence of amitriptyline therapy on T cell phenotype in chronic pain patientsIn: Biomedicine & Pharmacotherapy, Jg. 191, 2025, 118529DOI (Open Access)
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Influenza A Infection Increases Severity of Acute Ischemic Stroke Through Neutrophil Activation and HypercoagulabilityIn: Stroke, Jg. 56, 2025, Nr. 12, S. 3500 – 3511
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Lifestyle Intervention Modulates the CD4+ T Cell Profile in the Blood of Crohn’s Disease PatientsIn: Inflammatory Bowel Diseases, Jg. 31, 2025, Nr. 1, S. 200 – 209
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Preoperative immunotherapy with atezolizumab and tiragolumab in patients with colorectal liver metastases : The PURPLE trialIn: ESMO Gastrointestinal Oncology, Jg. 9, 2025, 100226DOI (Open Access)
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Red pulp macrophages clear parasites, while marginal metallophilic and marginal zone macrophages support CD4+ T cell activation during Plasmodium yoelii infectionIn: Frontiers in Immunology, Jg. 16, 2025, 1607201DOI, Online Volltext (Open Access)
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Thyroid hormone receptor α signaling shapes innate and adaptive immune responses during viral infectionIn: European Thyroid Journal, 2025, in pressDOI (Open Access)
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Direct effects of heroin and methadone on T cell functionIn: International Immunopharmacology, Jg. 140, 2024, 112736DOI (Open Access)
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Evaluation of a Multimodal Stress Management and Comprehensive Lifestyle Modification Program on Quality of Life and Gastrointestinal Symptoms in Patients with Crohn's Disease : A Randomized Controlled Pilot Trial with 9-Month Follow-UpIn: Digestion, Jg. 105, 2024, Nr. 3, S. 201 – 212
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Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour controlIn: PLoS Pathogens, Jg. 20, 2024, Nr. 1, e1011982DOI (Open Access)
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Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female miceIn: iScience, Jg. 27, 2024, Nr. 8, 110547DOI (Open Access)
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The ST2⁺ Treg/amphiregulin axis protects from immune-mediated hepatitisIn: Frontiers in Immunology, Jg. 15, 2024, 1351405DOI (Open Access)
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Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cellsIn: European Journal of Immunology, Jg. 53, 2023, Nr. 2, 2249940DOI, Online Volltext (Open Access)
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Barium sulphate microparticles are taken up by three different cell types: HeLa, THP-1, and hMSCIn: Acta Biomaterialia, Jg. 164, 2023, S. 577 – 587
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CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophilsIn: International Journal of Cardiology (IJC) Heart & Vasculature, Jg. 48, 2023, 101269DOI, Online Volltext (Open Access)
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Independent human mesenchymal stromal cell–derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease modelIn: Cytotherapy, 2023DOI (Open Access)
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Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirusIn: npj Vaccines, Jg. 8, 2023, Nr. 1, 8DOI, Online Volltext (Open Access)
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Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infectionsIn: PLoS Pathogens, Jg. 19, 2023, Nr. 11, e1011837DOI (Open Access)
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Substantial heterogeneity of inflammatory cytokine production and its inhibition by a triple cocktail of toll-like receptor blockers in early sepsisIn: Frontiers in Immunology, Jg. 14, 2023, 1277033DOI, Online Volltext (Open Access)
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Treatment with Helicobacter pylori-derived VacA attenuates allergic airway diseaseIn: Frontiers in Immunology, Jg. 14, 2023, 1092801DOI, Online Volltext (Open Access)
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B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healingIn: Immunity, Jg. 55, 2022, Nr. 12, S. 2336 – 2351.e12DOI (Open Access)
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Bacteria (E. coli) take up ultrasmall gold nanoparticles (2 nm) as shown by different optical microscopic techniques (CLSM, SIM, STORM)In: Nano Select, Jg. 3, 2022, Nr. 10, S. 1407 – 1420DOI, Online Volltext (Open Access)
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CD47 restricts antiviral function of alveolar macrophages during influenza virus infectionIn: iScience, Jg. 25, 2022, Nr. 12, 105540DOI (Open Access)
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Cell-intrinsic ceramides determine T cell function during melanoma progressionIn: eLife, Jg. 11, 2022, e83073DOI (Open Access)
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DJ-1 depletion prevents immunoaging in T-cell compartmentsIn: EMBO Reports, Jg. 23, 2022, Nr. 3, e53302DOI (Open Access)
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Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteriaIn: PLoS ONE, Jg. 17, 2022, Nr. 8, e0273247DOI, Online Volltext (Open Access)
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Peripheral blood iNKT cell activation correlates with liver damage during acute hepatitis CIn: JCI Insight, Jg. 7, 2022, Nr. 2, e155432DOI (Open Access)
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The Fungal Gut Microbiome Exhibits Reduced Diversity and Increased Relative Abundance of Ascomycota in Severe COVID-19 Illness and Distinct Interconnected Communities in SARS-CoV-2 Positive PatientsIn: Frontiers in Cellular and Infection Microbiology, Jg. 12, 2022, 848650DOI, Online Volltext (Open Access)
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The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesisIn: eLife, Jg. 11, 2022, e77975DOI, Online Volltext (Open Access)
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The interplay of thyroid hormones and the immune system : where we stand and why we need to know about itIn: European Journal of Endocrinology (EJE), Jg. 168, 2022, Nr. 5, S. R65 – R77DOI, Online Volltext (Open Access)
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Uptake of Functional Ultrasmall Gold Nanoparticles in 3D Gut Cell ModelsIn: Small, 2022, 2201167DOI (Open Access)
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A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19In: Frontiers in Cellular and Infection Microbiology, Jg. 11, 2021, 747816DOI, Online Volltext (Open Access)
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A combination of anti-pd-l1 treatment and therapeutic vaccination facilitates improved retroviral clearance via reactivation of highly exhausted t cellsIn: mBio, Jg. 12, 2021, Nr. 1, S. e02121 – 20DOI (Open Access)
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Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR), Jg. 36, 2021, Nr. 5, S. 968 – 985DOI, Online Volltext (Open Access)
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GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancerIn: Cancer Research, Jg. 81, 2021, Nr. 11, S. 2970 – 2982DOI (Open Access)
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Heroin-assisted treatment of heroin-addicted patients normalizes regulatory T cells but does not restore CD4⁺ T cell proliferationIn: Addiction Biology, Jg. 26, 2021, Nr. 4, S. e12998DOI (Open Access)
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IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute ColitisIn: Frontiers in Immunology, Jg. 12, 2021, 669787DOI, Online Volltext (Open Access)
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Inhibition of TLR4 Signaling Impedes Tumor Growth in Colitis-Associated Colon CancerIn: Frontiers in Immunology, Jg. 12, 2021, 669747DOI, Online Volltext (Open Access)
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Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunityIn: Mucosal Immunology, Jg. 14, 2021, Nr. 4, S. 923 – 936DOI (Open Access)
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Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced diseaseIn: Microbiome, Jg. 9, 2021, Nr. 1, 45DOI (Open Access)
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Neuropilin-1 is expressed on highly activated cd4+ effector t cells and dysfunctional cd4+ conventional t cells from naive miceIn: The Journal of Immunology (JI), Jg. 207, 2021, Nr. 5, S. 1288 – 1297
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Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DMIn: Blood, Jg. 137, 2021, Nr. 7, S. 923 – 928DOI (Open Access)
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CEACAM1 regulates CD8⁺ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitisIn: Gut Microbes, Jg. 11, 2020, Nr. 6, S. 1790 – 1805DOI (Open Access)
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens, Jg. 16, 2020, Nr. 3, e1008340DOI (Open Access)
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Common Pathways in Depression and Obesity : The Role of Gut Microbiome and DietsIn: Current Behavioral Neuroscience Reports, Jg. 7, 2020, Nr. 1, S. 15 – 21
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Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiomeIn: Immunology, Jg. 159, 2020, Nr. 3, S. 344 – 353DOI (Open Access)
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Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8+ T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery SystemIn: Vaccines, Jg. 8, 2020, Nr. 1, 110DOI, Online Volltext (Open Access)
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Endogenous CD83 Expression in CD4⁺ Conventional T Cells Controls Inflammatory Immune ResponsesIn: The Journal of Immunology (JI), Jg. 204, 2020, Nr. 12, S. 3217 – 3226
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Gute Mikroben, schlechte Mikroben : Ist die Darm-Mikrobiota Teil des Problems oder die Lösung bei chronisch-entzündlichen Darmerkrankungen?In: Unikate: Berichte aus Forschung und Lehre, 2020, Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 48 – 61DOI, Online Volltext (Open Access)
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In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CTIn: Acta Biomaterialia, Jg. 109, 2020, S. 244 – 253
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A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism, Jg. 1, 2019, Nr. 2, S. 236 – 250DOI, Online Volltext (Open Access)
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A tumor-peptide–based nanoparticle vaccine elicits efficient tumor growth control in antitumor immunotherapyIn: Molecular Cancer Therapeutics, Jg. 18, 2019, Nr. 6, S. 1069 – 1080DOI (Open Access)
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Diverse immunomodulatory effects of individual IFNα subtypes on virus-specific CD8⁺ T cell responsesIn: Frontiers in Immunology, Jg. 10, 2019, 2255DOI, Online Volltext (Open Access)
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Early suppression of peripheral mononuclear blood cells in sepsis in response to stimulation with cytomegalovirus, OKT3, and pokeweed mitogenIn: Journal of Applied Physiology, Jg. 127, 2019, Nr. 6, S. 1539 – 1547DOI (Open Access)
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Intestinal acid sphingomyelinase protects from severe pathogen-driven colitisIn: Frontiers in Immunology, Jg. 10, 2019, 1386DOI, Online Volltext (Open Access)
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MicroRNA-183 and microRNA-96 are associated with autoimmune responses by regulating T cell activationIn: Journal of Autoimmunity, Jg. 96, 2019, S. 94 – 103
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T cell-specific overexpression of acid sphingomyelinase results in elevated T cell activation and reduced parasitemia during Plasmodium yoelii infectionIn: Frontiers in Immunology, Jg. 10, 2019, S. 1225DOI (Open Access)
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The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancerIn: Mucosal Immunology, Jg. 12, 2019, Nr. 4, S. 990 – 1003DOI (Open Access)
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A systematic electron microscopic study on the uptake of barium sulphate nano-, submicro-, microparticles by bone marrow-derived phagocytosing cellsIn: Acta Biomaterialia, Jg. 80, 2018, S. 352 – 363
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CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infectionIn: Nature Communications, Jg. 9, 2018, 2561DOI (Open Access)
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IL-1β as mucosal vaccine adjuvant : the specific induction of tissue-resident memory T cells improves the heterosubtypic immunity against influenza A virusesIn: Mucosal Immunology, Jg. 11, 2018, Nr. 4, S. 1265 – 1278DOI (Open Access)
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Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral InfectionIn: Frontiers in Immunology, Jg. 9, 2018, 614DOI (Open Access)
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Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications, Jg. 8, 2017, 15440DOI (Open Access)
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Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivoIn: Acta Biomaterialia, Jg. 57, 2017, S. 414 – 425
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Conventional CD11chigh Dendritic Cells Are Important for T Cell Priming during the Initial Phase of Plasmodium yoelii Infection, but Are Dispensable at Later Time PointsIn: Frontiers in Immunology, Jg. 8, 2017, 1333DOI, Online Volltext (Open Access)
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DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4+IL-10+ Regulatory T Cells during Plasmodium yoelii InfectionIn: Frontiers in Immunology, Jg. 8, 2017, 152DOI, Online Volltext (Open Access)
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Delivery of the TLR ligand poly(I:C) to liver cells in vitro and in vivo by calcium phosphate nanoparticles leads to a pronounced immunostimulationIn: Acta Biomaterialia, Jg. 64, 2017, S. 401 – 410
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Differential expression of GPR15 on T cells during ulcerative colitisIn: JCI Insight, Jg. 2, 2017, Nr. 8, e90585DOI (Open Access)
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Helminth-induced intestinal inflammation facilitates tumor growth and progression in colitis-associated colon cancer
47th Annual meeting [of the] German Society of Immunology (DGfI), 15.–17.09.2017, Erlangen,In: European Journal of Immunology, Jg. 47, 2017, Nr. S2: 47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 67 -
Hypoxia enhances immunosuppression by inhibiting CD4+ Effector T cell function and promoting treg activityIn: Cellular Physiology and Biochemistry, Jg. 41, 2017, Nr. 4, S. 1271 – 1284DOI (Open Access)
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Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancerIn: PLoS Pathogens, Jg. 13, 2017, Nr. 9, e1006649DOI (Open Access)
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Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammationIn: Nanomedicine: Nanotechnology, Biology, and Medicine, Jg. 13, 2017, Nr. 8, S. 2395 – 2403
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology, Jg. 13, 2017, Nr. 1, e1005362DOI, Online Volltext (Open Access)
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Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced ImmunosuppressionIn: Frontiers in Immunology, Jg. 8, 2017, 1622DOI (Open Access)
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Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivoIn: Journal of Controlled Release, Jg. 222, 2016, S. 86 – 96
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Combination of nanoparticle‑based therapeutic vaccination and transient ablation of regulatory T cells enhances anti‑viral immunity during chronic retroviral infectionIn: Retrovirology, Jg. 13, 2016, 24DOI (Open Access)
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Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugatesIn: Scientific Reports, Jg. 6, 2016, 28709DOI, Online Volltext (Open Access)
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Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung FibrosisIn: Cancer Research, Jg. 76, 2016, Nr. 10, S. 3045 – 3056DOI (Open Access)
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IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sitesIn: Mucosal Immunology, Jg. 9, 2016, Nr. 5, S. 1263 – 1277DOI (Open Access)
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Mitochondrial DNA : an endogenous trigger for immune paralysisIn: Anesthesiology, Jg. 124, 2016, Nr. 4, S. 923 – 933
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Nanoparticles as transfection agents : a comprehensive study with ten different cell linesIn: RSC Advances, Jg. 6, 2016, Nr. 22, S. 18102 – 18112DOI (Open Access)
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Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cellsIn: Immunology, Jg. 148, 2016, Nr. 2, S. 197 – 205DOI, Online Volltext (Open Access)
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Targeting Antigens to Dec-205 on Dendritic Cells Induces Immune Protection in Experimental Colitis in MiceIn: European Journal of Microbiology and Immunology, Jg. 6, 2016, Nr. 1, S. 1 – 8DOI (Open Access)
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CEACAM1 induces B-cell survival and is essential for protective antiviral antibody productionIn: Nature Communications, Jg. 6, 2015, 6217DOI (Open Access)
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Gene silencing of the pro-inflammatory cytokine TNF-alpha with siRNA delivered by calcium phosphate nanoparticles, quantified by different methodsIn: Journal of Materials Chemistry B: Materials for Biology and Medicine, Jg. 3, 2015, Nr. 36, S. 7186 – 7193DOI (Open Access)
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IL10-Deficiency in CD4⁺ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced ColitisIn: Cellular Physiology and Biochemistry, Jg. 36, 2015, Nr. 4, S. 1259 – 1273DOI (Open Access)
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Relevance of Foxp3+ regulatory T cells for early and late phases of murine sepsisIn: Immunology, Jg. 146, 2015, Nr. 1, S. 144 – 156DOI (Open Access)
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The potential of nanoparticles for the immunization against viral infectionsIn: Journal of Materials Chemistry B: Materials for Biology and Medicine, Jg. 3, 2015, Nr. 24, S. 4767 – 4779DOI (Open Access)
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Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapyIn: Microbial Cell Factories, Jg. 14, 2015, 199DOI (Open Access)
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Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry, Jg. 36, 2015, Nr. 6, S. 2379 – 2392DOI (Open Access)
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Calcium phosphate nanoparticles show an effective activation of the innate immune response in vitro and in vivo after functionalization with flagellinIn: Virologica Sinica, Jg. 29, 2014, Nr. 1, S. 33 – 39DOI, Online Volltext (Open Access)
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Distinct Kinetics in the Frequency of Peripheral CD4+ T Cells in Patients with Ulcerative Colitis Experiencing a Flare during Treatment with Mesalazine or with a Herbal Preparation of Myrrh, Chamomile, and Coffee CharcoalIn: PLoS ONE, Jg. 9, 2014, Nr. 8, e104257DOI (Open Access)
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Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic ShockIn: PLoS ONE, Jg. 9, 2014, Nr. 8, e104953DOI (Open Access)
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Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infectionIn: Nanomedicine: Nanotechnology, Biology, and Medicine, Jg. 10, 2014, Nr. 8, S. 1787 – 1798
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Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune responseIn: Immunology and Cell Biology, Jg. 92, 2014, Nr. 10, S. 860 – 871
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The sympathetic nervous system modulates CD4+Foxp3+ regulatory T cells via noradrenaline-dependent apoptosis in a murine model of lymphoproliferative diseaseIn: Brain, Behavior and Immunity, Jg. 38, 2014, S. 100 – 110
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The type of adjuvant strongly influences the T-cell response during nanoparticle-based immunizationIn: Human Vaccines & Immunotherapeutics, Jg. 10, 2014, Nr. 1, S. 164 – 169DOI, Online Volltext (Open Access)
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Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cellsIn: Radiation Oncology, Jg. 9, 2014, Nr. 1, 98DOI (Open Access)
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Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancerIn: Cancer Research, Jg. 74, 2014, Nr. 16, S. 4258 – 4269
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An increased alveolar CD4 + CD25 + Foxp3 + T-regulatory cell ratio in acute respiratory distress syndrome is associated with increased 30-day mortalityIn: Intensive Care Medicine, Jg. 39, 2013, Nr. 10, S. 1743 – 1751DOI, Online Volltext (Open Access)
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Applications of nanoparticles for treating cutaneous infectionIn: Journal of Investigative Dermatology, Jg. 133, 2013, Nr. 5, S. 1133 – 1135DOI (Open Access)
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Immunization with biodegradable nanoparticles efficiently induces cellular immunity and protects against influenza virus infectionIn: The Journal of Immunology (JI), Jg. 190, 2013, Nr. 12, S. 6221 – 6229DOI (Open Access)
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Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cellsIn: Acta Biomaterialia, Jg. 9, 2013, Nr. 7, S. 7527 – 7535
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Calcium phosphate nanoparticles as versatile carrier for small and large molecules across cell membranesIn: Journal of Nanoparticle Research, Jg. 14, 2012, Nr. 6, 0910
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Cell targeting by antibody-functionalized calcium phosphate nanoparticlesIn: Journal of Materials Chemistry, Jg. 22, 2012, Nr. 2, S. 396 – 404
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Gut inflammation can boost horizontal gene transfer between pathogenic and commensal EnterobacteriaceaeIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 109, 2012, Nr. 4, S. 1269 – 1274DOI (Open Access)
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HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cellsIn: International Immunology, Jg. 24, 2012, Nr. 8, S. 485 – 494DOI (Open Access)
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Neuropilin 1 deficiency on CD4⁺Foxp3⁺ regulatory T cells impairs mouse melanoma growthIn: Journal of Experimental Medicine (JEM), Jg. 209, 2012, Nr. 11, S. 2001 – 2016DOI (Open Access)
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Opioid maintenance therapy restores CD4⁺ T cell function by normalizing CD4⁺CD25hⁱgh regulatory T cell frequencies in heroin userIn: Brain, Behavior and Immunity, Jg. 26, 2012, Nr. 6, S. 972 – 978
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Strong impact of CD4 ⁺Foxp3 ⁺ regulatory T cells and limited effect of T cell-derived IL-10 on pathogen clearance during Plasmodium yoelii infectionIn: The Journal of Immunology (JI), Jg. 188, 2012, Nr. 11, S. 5467 – 5477DOI (Open Access)
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ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X ReceptorsIn: Science Signaling, Jg. 4, 2011, Nr. 162, ra12DOI, Online Volltext (Open Access)
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Generation and function of immunosuppressive human and murine CD8⁺ T cells by transforming growth factor-β and retinoic acidIn: Immunology, Jg. 134, 2011, Nr. 1, S. 82 – 92DOI (Open Access)
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In vitro induced CD8+ regulatory T cells inhibit skin inflammationIn: European Journal of Microbiology and Immunology, Jg. 1, 2011, Nr. 3, S. 208 – 214DOI, Online Volltext (Open Access)
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Quantitative determination of the composition of multi-shell calcium phosphate-oligonucleotide nanoparticles and their application for the activation of dendritic cellsIn: Acta Biomaterialia, Jg. 7, 2011, Nr. 11, S. 4029 – 4036
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Inflammation in vivo is modulated by gpr83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cellsIn: Genes and Immunity, Jg. 11, 2010, Nr. 4, S. 357 – 361
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Local induction of immunosuppressive CD⁸ T cells in the gut-associated lymphoid tissuesIn: PLoS ONE, Jg. 5, 2010, Nr. 10, e15373DOI (Open Access)
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Retinoic acid-induced gut tropism improves the protective capacity of Treg in acute but not in chronic gut inflammationIn: European Journal of Immunology, Jg. 40, 2010, Nr. 9, S. 2539 – 2548DOI (Open Access)
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T cells, dendritic cells and epithelial cells in intestinal homeostasisIn: International Journal of Medical Microbiology (IJMM), Jg. 300, 2010, Nr. 1, S. 11 – 18
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The use of calcium phosphate nanoparticles encapsulating toll-like receptor ligands and the antigen hemagglutinin to induce dendritic cell maturation and T cell activationIn: Biomaterials, Jg. 31, 2010, Nr. 21, S. 5627 – 5633
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CD4⁺Foxp3⁺ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cellsIn: Gut, Jg. 58, 2009, Nr. 2, S. 211 – 219
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CD83 expression in CD4⁺ T cells modulates inflammation and autoimmunityIn: The Journal of Immunology (JI), Jg. 180, 2008, Nr. 9, S. 5890 – 5897DOI (Open Access)
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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxinsIn: Nature, Jg. 453, 2008, Nr. 7191, S. 106 – 109DOI, Online Volltext (Open Access)
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Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3⁻CD25⁻ regulatory T cellsIn: The Journal of Immunology (JI), Jg. 179, 2007, Nr. 12, S. 8059 – 8068DOI (Open Access)
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Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrityIn: PLoS ONE, Jg. 2, 2007, Nr. 12, e1308DOI (Open Access)
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Autoimmune-Mediated Intestinal Inflammation-Impact and Regulation of Antigen-Specific CD8⁺ T CellsIn: Gastroenterology, Jg. 131, 2006, Nr. 2, S. 510 – 524
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Cd14, Gbp1, and Pla2g2a : Three major candidate genes for experimental IBD identified by combining QTL and microarray analysesIn: Physiological Genomics, Jg. 25, 2006, Nr. 3, S. 426 – 434DOI (Open Access)
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G protein-coupled receptor 83 overexpression in naive CD4 ⁺CD25⁻ T cells leads to the induction of Foxp3⁺ regulatory T cells in vivoIn: The Journal of Immunology (JI), Jg. 177, 2006, Nr. 1, S. 209 – 215DOI (Open Access)
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Signatures of human regulatory T cells : An encounter with old friends and new playersIn: Genome Biology, Jg. 7, 2006, Nr. 7, R54DOI (Open Access)
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CD4⁺ T cell mediated intestinal immunity : Chronic inflammation versus immune regulationIn: Gut, Jg. 54, 2005, Nr. 1, S. 60 – 69DOI (Open Access)
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Mechanisms of central and peripheral T-cell tolerance : An updateIn: Transfusion Medicine and Hemotherapy, Jg. 32, 2005, Nr. 6, S. 384 – 399
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On the edge of autoimmunity : T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetesIn: Diabetes, Jg. 54, 2005, Nr. 12, S. 3395 – 3401
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The host response to the probiotic Escherichia coli strain Nissle 1917 : Specific up-regulation of the proinflammatory chemokine MCP-1In: BMC Medical Genetics, Jg. 6, 2005, 43DOI (Open Access)
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Frontline: Neuropilin-1 : A surface marker of regulatory T cellsIn: European Journal of Immunology, Jg. 34, 2004, Nr. 3, S. 623 – 630DOI (Open Access)
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The Mycoplasma-derived macrophage-activating 2-kilodalton lipopeptide triggers global immune activation on nasal mucosa-associated lymphoid tissuesIn: Infection and Immunity, Jg. 72, 2004, Nr. 12, S. 6978 – 6986DOI, Online Volltext (Open Access)
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EditorialIn: Unikate: Berichte aus Forschung und Lehre. Duisburg, Essen: Universität Duisburg-Essen, 2020, Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 6 – 7DOI, Online Volltext (Open Access)
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Editorial : Cancer, drugs, and bugs—Bacteriotherapy on the rise?In: Journal of Leukocyte Biology (JLB). Hoboken: Wiley, Jg. 103, 2018, Nr. 5, S. 795 – 797
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Graduiertenkollegs sind ein großes Plus : Ein Gespräch mit der Sprecherin des Graduiertenkollegs „Immunantwort in Infektionskrankheiten“ (GRK 1949), Prof. Dr. Astrid Westendorf und der Koordinatorin des Kollegs, Daniela Catrini M.A.In: Unikate: Berichte aus Forschung und Lehre. Duisburg, Essen: Universität Duisburg-Essen, 2020, Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 82 – 85DOI, Online Volltext (Open Access)
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Memory CD4+ T Cells Recognize Divergent HLA-DP Immunopeptidomes and Contribute to Leukemia Control after Allogeneic HCT
The 66th ASH Annual Meeting, December 7-10, 2024, San Diego, USA,In: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 144, 2024, Nr. Supplement 1, S. 901DOI (Open Access) -
Das vakuolsisierende Zytotoxin (VacA) reduziert Atemwegsinflammation, Mukusproduktion und subepitheliale Fibrose in einem therapeutischen Modell
63. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V.,In: Pneumologie. Stuttgart: Thieme, Jg. 77, 2023, Nr. S 01, S. S62 -
Session 5: Biomaterials - Inorganic : Calcium phosphate nanoparticles as a delivery of bioactive compounds to the liver and for imaging and vaccination
Annual Conference of the German Society for Biomaterials e.V., 08,-10.11.2018, Braunschweig-Stöckheim,In: Biomedical engineering = Biomedizinische Technik. Berlin; Berlin1: de Gruyter, Jg. 64, 2019, Nr. s1: Abstracts of the 2018 Annual Meeting of the German Society for Biomaterials, S. 36 – 40DOI (Open Access) -
Analysis of the gut microbiome in Foxp3+Regulatory T cell depleted mice
47th Annual meeting [of the] German Society of Immunology (DGfI), 15.–17.09.2017, Erlangen,In: European Journal of Immunology. Hoboken: Wiley, Jg. 47, 2017, Nr. S2: 47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 212DOI (Open Access) -
Loss or therapeutic inhibition of extracellular adenosine production by ecto-5 -nucleotidase(CD73) attenuates radiation-induced lung fibrosis
European Cancer Congress (ECC 2015), 25.-29.09.2015, Wien,In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 51, 2015, Nr. Supplement 3, S. S117 – S118 -
Ein Vergleich der Genstummschaltungseffizienz unterschiedlicher nanopartikulärer SystemeIn: BioNanoMaterials. Berlin: De Gruyter, Jg. 15, 2014, Nr. S 1, S. 80
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Prophylaktische Vakzinierung gegen Tumoren mit funktionalisierten Calciumphosphat-Nanopartikeln in einem murinen Tumortransplantations- Modell
Annual conference of the German Society of Biomaterials (DGBM) , 06.-08.11.2014, Dresden,In: BioNanoMaterials. Berlin: De Gruyter, Jg. 15, 2014, Nr. Supplement, V5 -
Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+FoxP3+regulatory T cells
20. Jahreskongress der Deutschen Gesellschaft für Radioonkologie (DEGRO), 03.-06.07.2014, Düsseldorf,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 190, 2014, Nr. Suppl.1: Abstract-Band DEGRO 2014, S. 59 – 60 -
Whole thorax irradiation initiates a local and systemic accumulation of immunosuppressive FoxP3+regulatory T cells
23rd Biennial Congress of the European Association for Cancer Research, 05.–08.07.2014, München,In: European Journal of Cancer (EJC). Amsterdam: Elsevier, Jg. 50, 2014, Nr. Suppl. 5, S. S223 -
Effective immunmodulation by biodegradable calcium phosphate nanoparticles confers strong antiviral protection
65th Annual Meeting of the German Society for Hygiene and Microbiology (DGHM), 22.-25.09.2013, Rostock,In: International Journal of Medical Microbiology (IJMM). Amsterdam: Elsevier, Jg. 303, 2013, Nr. Suppl. 1, S. 38 – 38 -
Impact of IL-10 in Citrobacter rodentium induced intestinal inflammation
65th Annual Meeting of the German Society for Hygiene and Microbiology (DGHM), 22.-25.09.2013, Rostock,In: International Journal of Medical Microbiology (IJMM). Amsterdam: Elsevier, Jg. 303, 2013, Nr. Suppl. 1, S. 35 – 35 -
Lymphocytes play a role in radiation-induced pneumopathyIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics. Heidelberg: Springer, Jg. 188, 2012, Nr. Suppl.1: Abstract-Band DEGRO 2014, S. 126 – 127
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Intestinal epithelial antigen induces CD4⁺ T cells with regulatory phenotype in a transgenic autoimmune mouse modelIn: Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways / International Symposium Inflammatory Bowel Disease: Research Drives Clinics Genetics, Barrier Function, Immunological and Microbial Pathways, 01.-03.09.2005, Münster / Domschke, Wolfram W. (Hrsg.). Boston, Mass.: Blackwell, 2006, S. 401 – 406
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Cytomegalovirus infection aggravates intestinal inflammation during colitis and impairs the convalescence of the intestinal niche
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology. Hoboken: Wiley, Jg. 53, 2023, Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 354DOI (Open Access) -
Impact of chronic intestinal inflammation on colonic immune responses to secondary challenge with Citrobacter rodentium
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology. Hoboken: Wiley, Jg. 53, 2023, Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 362DOI (Open Access) -
Respiratory but not systemic viral infection induces tumour growth inhibition through CD8+T-cell activation
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology. Hoboken: Wiley, Jg. 53, 2023, Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 189DOI (Open Access) -
Vacuolating Cytotoxin A (VacA) : Therapeutic Potential of a Helicobacter Derived Molecule for Asthma
International Conference of the American Thoracic Society (ATS) 2022 ; May 13-18, 2022, San Francisco, CA, USA,In: American Journal of Respiratory and Critical Care Medicine (AJRCCM). New York: American Thoracic Society, Jg. 205, 2022, Nr. Supplement, A3749