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Institut für Pharmakogenetik am Universitätsklinikum Essen
Funktionen
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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Pharmakogenetik
Aktuelle Veranstaltungen
Keine aktuellen Veranstaltungen.
Vergangene Veranstaltungen (max. 10)
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2017 SS
- Kurs Klinische Pharmakologie/Pharmakotherapie, Teil II (5. Sem. des zweiten Studienabschnitts) (PV)
- Pharmakologie, Toxikologie, Teil II (Grundlage zum Kurs Pharmakologie, Toxikologie, Teil II)
- Kurs Klinische Pharmakologie/Pharmakotherapie, Teil I (3. Semester des zweiten Studienabschnitts) (PV)
- Klinische Pharmakologie/Pharmakotherapie (Grundlage zum Kurs Klinische Pharmakologie/Pharmakotherapie, Teil II)
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2016 WS
- Kurs Klinische Pharmakologie/Pharmakotherapie, Teil II (5. Sem. des zweiten Studienabschnitts) (PV)
- Pharmakologie, Toxikologie, Teil II (Grundlage zum Kurs Pharmakologie, Toxikologie, Teil II)
- Klinische Pharmakologie/Pharmakotherapie (Grundlage zum Kurs Klinische Pharmakologie/Pharmakotherapie, Teil II)
- Kurs Klinische Pharmakologie/Pharmakotherapie, Teil I (3. Semester des zweiten Studienabschnitts) (PV)
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2016 SS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Association of the dopamine D2 receptor gene SNP rs1800497 with postoperative nausea and vomiting : A prospective cohort studyIn: European Journal of Anaesthesiology and Intensive Care (EJAIC) Jg. 3 (2024) Nr. 4, e0056Online Volltext: dx.doi.org/ (Open Access)
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Patients’ and physicians’ awareness of clinical symptoms and disease severity in tuberous sclerosis complexIn: Orphanet Journal of Rare Diseases Jg. 19 (2024) Nr. 1, 106Online Volltext: dx.doi.org/ (Open Access)
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Characterization of the promoter of the human farnesyltransferase beta subunit and the impact of the transcription factor OCT-1 on its expressionIn: Genomics Jg. 114 (2022) Nr. 2, 110314Online Volltext: dx.doi.org/ (Open Access)
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FNTB Promoter Polymorphisms Are Independent Predictors of Survival in Patients with Triple Negative Breast CancerIn: Cancers Jg. 14 (2022) Nr. 3, 468Online Volltext: dx.doi.org/ (Open Access)
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Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors : Results of the Heinz Nixdorf Recall StudyIn: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 394 (2021) Nr. 8, S. 1713 - 1725Online Volltext: dx.doi.org/ (Open Access)
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Thrombospondin‐2 and ldh are putative predictive biomarkers for treatment with everolimus in second‐line metastatic clear cell renal cell carcinoma (Marc‐2 study)In: Cancers Jg. 13 (2021) Nr. 11, 2594Online Volltext: dx.doi.org/ (Open Access)
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Genetic contribution to PONV riskIn: Anaesthesia Critical Care & Pain Medicine Jg. 39 (2020) Nr. 1, S. 45 - 51Online Volltext: dx.doi.org/
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Genetic risk scores for coronary artery disease and its traditional risk factors : Their role in the progression of coronary artery calcification ; Results of the Heinz Nixdorf Recall studyIn: PLoS ONE Jg. 15 (2020) Nr. 5, S. e0232735Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Association of caspase 8 polymorphisms -652 6N InsDel and Asp302His with progression-free survival and tumor infiltrating lymphocytes in early breast cancerIn: Scientific Reports Jg. 9 (2019) Nr. 1, S. 12594Online Volltext: dx.doi.org/ (Open Access)
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SNPs Within the MTOR Gene Are Associated With an Increased Risk of Developing De Novo Diabetes Mellitus Following the Administration of Everolimus in Liver Transplant RecipientsIn: Transplantation Proceedings Jg. 51 (2019) Nr. 6, S. 1962 - 1971Online Volltext: dx.doi.org/
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Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitroIn: Skin Pharmacology and Physiology Jg. 32 (2019) Nr. 3, S. 162 - 172Online Volltext: dx.doi.org/
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The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell linesIn: BMC Cancer Jg. 19 (2019) S. 243Online Volltext: dx.doi.org/ (Open Access)
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Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative PlasticisersIn: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 4, S. 1133Online Volltext: dx.doi.org/ (Open Access)
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CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effectiveIn: British Journal of Anaesthesia (BJA) Jg. 121 (2018) Nr. 1, S. 58 - 65Online Volltext: dx.doi.org/ (Open Access)
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No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip ArthroplastyIn: BioMed Research International (2018) 3687415Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A single intraperitoneal injection of bovine fetuin-A attenuates bone resorption in a murine calvarial model of particle-induced osteolysisIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Jg. 105 (2017) S. 262 - 268Online Volltext: dx.doi.org/
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Exploring the putative self-binding property of the human farnesyltransferase alpha-subunitIn: FEBS Letters Jg. 591 (2017) Nr. 21, S. 3637 - 3648Online Volltext: dx.doi.org/
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Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS).In: International Journal of Molecular Sciences (IJMS) Jg. 18 (2017) Nr. 6,Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Impact of BCL2 polymorphisms on survival in transitional cell carcinoma of the bladderIn: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 9, S. 1659 - 1670Online Volltext: dx.doi.org/
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Pharmacogenetic association of blood-lipid related genetic variants with 5-year progression of coronary artery calcification following the treatment with statin in the Heinz Nixdorf Recall studyIn: Atherosclerosis Jg. 263 (2017) S. e278Online Volltext: dx.doi.org/
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Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplastyIn: European Journal of Medical Research Jg. 22 (2017) S. 29Online Volltext: dx.doi.org/ (Open Access)
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A Single Dose of the Anti-Resorptive Peptide Human Calcitonin Paradoxically Augments Particle- and Endotoxin-Mediated Pro-Inflammatory Cytokine Production In VitroIn: Hormone and Metabolic Research Jg. 48 (2016) Nr. 9, S. 607 - 612Online Volltext: dx.doi.org/
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Association of a Common Oxytocin Receptor Gene Polymorphism with Self-Reported 'Empathic Concern' in a Large Population of Healthy VolunteersIn: PLoS ONE Jg. 11 (2016) Nr. 7, S. e0160059Online Volltext: dx.doi.org/ (Open Access)
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Caspase-8 Polymorphisms As Independent Prongostic Factors For Survival In Breast Cancer PatientsIn: International Journal of Gynecological Cancer Jg. 26 (2016) Nr. Suppl. 2, S. 30Online Volltext: dx.doi.org/
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Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis : a prospective observational trialIn: BMC Anesthesiology Jg. 16 (2016) Nr. 1, S. 61Online Volltext: dx.doi.org/ (Open Access)
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Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancerIn: BMC Cancer Jg. 16 (2016) S. 618Online Volltext: dx.doi.org/ (Open Access)
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Prognostische Relevanz von Caspase-8 Polymorphismen für das MammakarzinomIn: Geburtshilfe und Frauenheilkunde Jg. 76 (2016) Nr. 5, A 30Online Volltext: dx.doi.org/
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The BCL2 -938C>A Promoter Polymorphism is Associated with Risk for and Time to Aseptic Loosening of Total Hip ArthroplastyIn: PLoS ONE Jg. 11 (2016) Nr. 2, S. e0149528Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinomaIn: The Journal of Laryngology and Otology Jg. 129 (2015) Nr. 6, S. 580 - 586Online Volltext: dx.doi.org/
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Absence of telomerase reverse transcriptase promoter mutations in neuroblastomaIn: Biomedical Reports Jg. 3 (2015) Nr. 4, S. 443 - 446Online Volltext: dx.doi.org/
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Calcitonin Gene-Related Peptide Modulates the Production of Pro-Inflammatory Cytokines Associated with Periprosthetic Osteolysis by THP-1 Macrophage-Like CellsIn: Neuroimmunomodulation Jg. 22 (2015) Nr. 3, S. 152 - 165Online Volltext: dx.doi.org/
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Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imagingIn: Immunotherapy Jg. 7 (2015) Nr. 317, S. 317ra199Online Volltext: dx.doi.org/
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The FNTB promoter polymorphism rs11623866 as a potential predictive biomarker for lonafarnib treatment of ovarian cancer patientsIn: British Journal of Clinical Pharmacology (BJCP) Jg. 80 (2015) Nr. 5, S. 1139 - 1148Online Volltext: dx.doi.org/ (Open Access)
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A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1In: Molecular Cancer Jg. 13 (2014) 87Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The FNTB-609G>C polymorphism as a possible predictive factor for efficacy of lonafarnib-treatment? : Exploratory analysis of a randomized phase II clinical trial in stage IIb-IV ovarian cancer, treated with first-line platinum-based chemotherapy with or without lonafarnibIn: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15 Suppl., S. e16534Online Volltext: dx.doi.org/
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Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patientsIn: Journal of Neuro-Oncology Jg. 112 (2013) Nr. 2, S. 297 - 305Online Volltext: dx.doi.org/
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RANKL-associated suppression of particle-induced osteolysis in an aged model of Calcitonin and alpha-CGRP deficiency.In: Biomaterials Jg. 34 (2013) Nr. 12, S. 2911 - 2919Online Volltext: dx.doi.org/
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Risk factors for thrombus formation on the amplatzer cardiac plug after left atrial appendage occlusionIn: JACC Cardiovascular Interventions Jg. 6 (2013) Nr. 6, S. 606 - 613Online Volltext: dx.doi.org/
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The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemiaIn: BMC Cancer Jg. 13 (2013) S. 452Online Volltext: dx.doi.org/ (Open Access)
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HCV-HIV-coinfected Patients of the Competence Network for HIV/AIDS Cohort : Impact of IL28B Polymorphisms on Sustained Virological ResponseIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 10 (2012) Nr. Suppl. 3, S. 36 - 37
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The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell linesIn: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 385 (2012) Nr. Suppl. 1, S. 7 - 7
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Validation and Quantification of Osteoclasts as a Predictor of Polyethylene Particle Induced OsteolysisIn: Trends in Biomaterials and Artificial Organs Jg. 26 (2012) Nr. 4, S. 161 - 166
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Association of the CC genotype of the regulatory BCL2 promoter polymorphism (−938C>A) with better 2-year survival in patients with glioblastoma multiformeIn: Journal of Neurosurgery (JNS) Jg. 114 (2011) Nr. 6, S. 1631 - 1639Online Volltext: dx.doi.org/
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Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysisIn: BMC Musculoskeletal Disorders Jg. 12 (2011) S. 186Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary NeuroblastomaIn: Clinical Cancer Research Jg. 17 (2011) Nr. 15, S. 5082 - 5092Online Volltext: dx.doi.org/
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Influence of the 393T>C Polymorphism of the GNAS1 Gene on the Intensity of Opiate WithdrawalIn: Pharmacopsychiatry Jg. 44 (2011) Nr. 4, S. 159 - 160Online Volltext: dx.doi.org/
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Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinomaIn: International Journal of Cancer Jg. 129 (2011) Nr. 10, S. 2390 - 2399Online Volltext: dx.doi.org/
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The prevalence of the c-kit exon 10 variant, M541L, in aggressive fibromatosis does not differ from the general populationIn: Journal of Clinical Pathology: JCP Online Jg. 64 (2011) Nr. 11, S. 1021 - 1024Online Volltext: dx.doi.org/
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Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomasIn: Journal of Translational Medicine Jg. 9 (2011) S. 139Online Volltext: dx.doi.org/ (Open Access)
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A rare case of propofol-induced acute liver failure and literature reviewIn: Case Reports in Gastroenterology Jg. 4 (2010) Nr. 1, S. 57 - 65Online Volltext: dx.doi.org/ (Open Access)
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Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiformeIn: Journal of Cancer Research and Clinical Oncology Jg. 136 (2010) Nr. 9, S. 1423 - 1429Online Volltext: dx.doi.org/
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Biochemical markers of particle induced osteolysis in C57BL/6 miceIn: Clinical Chemistry & Laboratory Medicine Jg. 48 (2010) Nr. 11, S. 1641 - 1646Online Volltext: dx.doi.org/
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Gender‐dependent association of the GNAS1 T393C polymorphism with early aseptic loosening after total hip arthroplasty : Reply : Letters to the EditorsIn: Journal of Orthopaedic Research Jg. 28 (2010) Nr. 9, S. 1258Online Volltext: dx.doi.org/
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The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levelsIn: European Journal of Haematology Jg. 85 (2010) Nr. 2, S. 108 - 113Online Volltext: dx.doi.org/
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The XbaI G>T polymorphism of the glucose transporter 1 gene modulates ¹⁸F-FDG uptake and tumor aggressiveness in breast cancerIn: Journal of Nuclear Medicine (JNM) Jg. 51 (2010) Nr. 8, S. 1191 - 1197Online Volltext: dx.doi.org/ (Open Access)
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ALK Mutation Analysis in Patients of the German Neuroblastoma StudyIn: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 195Online Volltext: dx.doi.org/
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DNA repair gene XRCC1 polymorphisms and outcome of renal cell carcinoma in Caucasian patientsIn: Anticancer Research Jg. 29 (2009) Nr. 12, S. 5131 - 5135
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The regulatory BCL2 promoter polymorphism (-938C>A) is associated with relapse and survival of patients with oropharyngeal squamous cell carcinomaIn: Annals of Oncology Jg. 20 (2009) Nr. 6, S. 1094 - 1099Online Volltext: dx.doi.org/ (Open Access)
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The AA genotype of the regulatory BCL2 promoter polymorphism (-938C>A) is associated with a favorable outcome in lymph node negative invasive breast cancer patientsIn: Clinical Cancer Research Jg. 13 (2007) Nr. 19, S. 5790 - 5797Online Volltext: dx.doi.org/ (Open Access)
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MTOR polymorphisms and de novo diabetes mellitus in liver transplantation patients treated with everolimus
87th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) ; 1 March – 3 March 2021, Digital,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 394 (2021) Nr. Suppl. 1, S. S25Online Volltext: dx.doi.org/ (Open Access) -
Association of Caspase 8 polymorphisms with TILs and disease-free survival in primary breast cancer patientsIn: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. e24258Online Volltext: dx.doi.org/ (Open Access)
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Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit
84th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 20th Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) ; 26 February – 1 March 2018. Göttingen,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 391 (2018) Nr. 1, Supplement, S. S66Online Volltext: dx.doi.org/ -
The BCL2-938C>A promoter polymorphism is associated with risk for and time to aseptic loosening of total hip arthroplasty
84th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 20th Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) ; 26 February – 1 March 2018, Göttingen,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 391 (2018) Nr. Suppl. 1, S73 Abstract P214Online Volltext: dx.doi.org/ -
The prognostic impact of UDP-glucuronyltransferase 1A1*1 (UGT1A1*1) polymorphism in patients with advanced colorectal and non-colorectal cancer treated with irinotecan-based systemic chemotherapies
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 122 - 123Online Volltext: dx.doi.org/ (Open Access) -
Characterization of the promoter region of a variant of the beta-subunit of the human farnesyltransferase
Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V., 81th Annual Meeting, March 10 - 12, 2015, Kiel, Germany,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 388 (2015) Nr. Suppl. 1, S. 54Online Volltext: dx.doi.org/ -
FNTB promoter polymorphisms influence survival in prostate cancer
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 80Online Volltext: dx.doi.org/ -
The FNTB-609G > C polymorphism as a possible predictive factor for efficacy of lonafarnib-treatment? : Exploratory analysis of a randomized phase II clinical trial in stage IIb-IV ovarian cancer, treated with first-line platinum-based chemotherapy with or without lonafarnib
Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V., 81th Annual Meeting, March 10 - 12, 2015, Kiel, Germany,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 388 (2015) Nr. Suppl. 1, S. 52Online Volltext: dx.doi.org/ -
High Expression of the alk Receptor Tyrosine Kinase Precedes Mutation as a Determining Factor of Unfavourable Phenotype in Primary Neuroblastoma
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer Jg. 55 (2010) Nr. 5, S. 827Online Volltext: dx.doi.org/ -
The T-allele of the GNB3 825C > T polymorphism is associated with increased intensity of opiate withdrawal
8th International Sphingolipid Club Meeting, Glasgow, UK, June 30 – July 2, 2010,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 381 (2010) Nr. Suppl. 1, S. 87Online Volltext: dx.doi.org/ -
Genetische Variabilität des BCL2 Gens - Untersuchungen zum molekularen Mechanismus und der klinischen Bedeutung des BCL2 -938C>A PromotorpolymorphismusDuisburg, Essen (2012) 1 CD-ROM
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Bedeutung von Polymorphismen im Gen GNAS1Duisburg, Essen (2007) 91 Bl. : Ill., graph. Darst.