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Dr. rer. nat. Ralf A. Hilger

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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Li, Xieran; Kalwak, Krzysztof; Beier, Rita; Kehne, Jochen; Möller, Ann-Kristin; Baumgart, Joachim; Beelen, Dietrich W.; Hilger, Ralf A.; Vora, Ajay; Sykora, Karl-Walter
    Population pharmacokinetic modeling of treosulfan and rationale for dose recommendation in children treated for conditioning prior to allogeneic hematopoietic stem cell transplantation
    In: Drug Metabolism and Pharmacokinetics, Jg. 52, 2023, 100515
    DOI (Open Access)
  • Groß, Elisabeth; Hilger, Ralf A.; Schümann, Franziska Lea; Bauer, Marcus; Bouska, Alyssa; Rohde, Christian; Willscher, Edith; Lützkendorf, Jana; Müller, Lutz Peter; Edemir, Bayram; Mueller, Thomas; Herling, Marco; Binder, Mascha; Wickenhauser, Claudia; Iqbal, Javeed; Posern, Guido; Weber, Thomas
    SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
    In: Cancers, Jg. 15, 2023, Nr. 11, 3043
    DOI (Open Access)
  • Schaller, Stephan; Martins, Frederico S.; Balazki, Pavel; Böhm, Sonja; Baumgart, Joachim; Hilger, Ralf A.; Beelen, Dietrich W.; Hemmelmann, Claudia; Ring, Arne
    Evaluation of the drug-drug interaction potential of treosulfan using a physiologically-based pharmacokinetic modelling approach
    In: British Journal of Clinical Pharmacology (BJCP), Jg. 88, 2022, Nr. 4, Landmarks in Pharmacometrics/Key Methods in Modelling and Simulation, S. 1722 – 1734
    DOI (Open Access)
  • Melnikova, Margarita; Wauer, Ulrike Sophie; Mendus, Diana; Hilger, Ralf Axel; Oliver, Trudy G.; Mercer, Kim; Gohlke, Björn Oliver; Erdmann, Kati; Niederacher, Dieter; Neubauer, Hans; Buderath, Paul; Wimberger, Pauline; Kuhlmann, Jan Dominik; Thomale, Jürgen
    Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells
    In: Molecular Oncology, Jg. 14, 2020, Nr. 4, S. 686 – 703
    DOI (Open Access)
  • Wichmann, Catharina; Klotz, Daniel Martin; Zeiler, Hans-Joachim; Hilger, Ralf A.; Grützmann, Konrad; Krüger, Alexander; Aust, Daniela; Wimberger, Pauline; Kuhlmann, Jan Dominik
    The effect of the triazene compound CT913 on ovarian cancer cells in vitro and its synergistic interaction with the PARP-inhibitor olaparib
    In: Gynecologic Oncology, Jg. 159, 2020, Nr. 3, S. 850 – 859
    DOI
  • Nemecek, Eneida R.; Hilger, Ralf A.; Adams, Alexia; Shaw, Bronwen E.; Kiefer, Deidre; Le-Rademacher, Jennifer; Levine, John E.; Yanik, Gregory; Leung, Wing; Talano, Julie-An; Haut, Paul; Delgado, David; Kapoor, Neena; Petrovic, Aleksandra; Adams, Roberta; Hanna, Rabi; Rangarajan, Hemalatha; Dalal, Jignesh; Chewning, Joseph; Verneris, Michael R.; Epstein, Stacy; Burroughs, Lauri; Perez-Albuerne, Evelio D.; Pulsipher, Michael A.; Delaney, Colleen
    Treosulfan, Fludarabine, and Low-Dose Total Body Irradiation for Children and Young Adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Cell Transplantation : Prospective Phase II Trial of the Pediatric Blood and Marrow Transplant Consortium
    In: Biology of Blood and Marrow Transplantation, Jg. 24, 2018, Nr. 8, S. 1651 – 1656
    DOI, Online Volltext (Open Access)
  • Athanasiadi, I.; Geigy, Caroline A.; Hilger, Ralf A.; Meier, Valeria; Rohrer Bley, Carla
    Safety, tolerability and pharmacokinetic properties of the novel triazene TriN 2755 in tumour bearing dogs : a phase I study
    In: Veterinary and Comparative Oncology, Jg. 15, 2017, Nr. 1, S. 94 – 104
    DOI (Open Access)
  • Joerger, Markus; Kraff, Stefanie; Jaehde, Ulrich; Hilger, Ralf A.; Courtney, Jodi B; Cline, Daniel J; Jog, Sonali; Baburina, Irina; Miller, M C; Salamone, Salvatore J
    Validation of a Commercial Assay and Decision Support Tool for Routine Paclitaxel Therapeutic Drug Monitoring (TDM)
    In: Therapeutic Drug Monitoring, Jg. 39, 2017, Nr. 6, S. 617 – 624
    DOI
  • Orthmann, Andrea; Hilger, Ralf A.; Hoffmann, Annika; Fichtner, Iduna; Peiker, Lisa; Zeisig, Reiner
    Improved treatment of MT-3 breast cancer and brain metastases in a mouse xenograft by LRP-targeted oxaliplatin liposomes
    In: Journal of Biomedical Nanotechnology, Jg. 12, 2016, Nr. 1, S. 56 – 68
    DOI
  • Kullmann, Maximilian; Kalayda, Ganna V.; Hellwig, Malte; Kotz, Sandra; Hilger, Ralf A.; Metzger, Sabine; Jaehde, Ulrich
    Assessing the contribution of the two protein disulfide isomerases PDIA1 and PDIA3 to cisplatin resistance
    In: Journal of Inorganic Biochemistry, Jg. 153, 2015, S. 247 – 252
    DOI
  • Joerger, Markus; Von Pawel, Joachim; Kraff, Stefanie; Fischer, Juergen R; Eberhardt, Wilfried; Gauler, Thomas; Mueller, Lothar; Reinmuth, Niels; Reck, Martin; Kimmich, Martin; Mayer, Frank; Kopp, Hans-Georg; Behringer, Dirk M.; Ko, Yon-Dschun; Frueh, Martin; Hilger, Ralf A.; Roessler, Max; Moritz, Berta; Jaehde, Ulrich
    Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin in advanced non-small cell lung cancer (NSCLC) patient
    In: Journal of Clinical Oncology (JCO), Jg. 33, 2015, Nr. 15_suppl, S. 8051
    DOI, Online Volltext
  • Van den Berg, P. J.; Ruppert, M.; Sykora, K. W.; Beier, R.; Beelen, Dietrich; Hilger, Ralf A.; Scheulen, Max Ernst; Wachowiak, J.; Nemecek, E. R.; Spaans, E.; Lioznov, M.; Pichlmeier, U.; Wullf, B.; Baumgart, J.
    A preliminary population pharmacokinetic model for doese selection of treosulfan used in conditioning treatment prior to haematopoietic stem cell transplantation (HSCT) in children
    In: Bone Marrow Transplantation, Jg. 49, 2014, Nr. Suppl. 1, S. S360 – S361
    DOI
  • Tippelt, Stephan; Mikasch, R.; Warmuth-Metz, M.; Pietsch, T.; Hilger, Ralf A.; Kwiecien, R.; Faldum, A.; Rutkowski, S.; Bode, U.; Siegler, N.; Fleischhack, Gudrun
    Intraventricular therapy with etoposide in recurrent medulloblastomas, pineoblastomas, CNS-PNETS ans ependymomas - final results of a PHASE II STUDY
    In: Neuro-Oncology, Jg. 16, 2014, Nr. Suppl. 1, S. 10
    DOI
  • Friesen, Claudia; Hormann, Inis; Roscher, Mareike; Fichtner, Iduna; Alt, Andreas; Hilger, Ralf A.; Debatin, Klaus-Michael; Miltner, Erich
    Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma
    In: Cell Cycle, Jg. 13, 2014, Nr. 10, S. 1560 – 1570
    DOI (Open Access)
  • Bauer, Sebastian; Hilger, Ralf A.; Mühlenberg, Thomas; Grabellus, Florian; Nagarajah, James; Hoiczyk, M.; Reichardt, A.; Ahrens, M.; Reichardt, P.; Grunewald, S.; Scheulen, Max Ernst; Pustowka, A.; Bock, E.; Schuler, Martin; Pink, D.
    Phase i study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors
    In: British Journal of Cancer (BJC), Jg. 110, 2014, Nr. 5, S. 1155 – 1162
    DOI (Open Access)
  • Friesen, Claudia; Roscher, Mareike; Hormann, Inis; Fichtner, Iduna; Alt, Andreas; Hilger, Ralf A.; Debatin, Klaus-Michael; Miltner, Erich
    Cell death sensitization of leukemia cells by opioid receptor activation
    In: OncoTarget, Jg. 4, 2013, Nr. 5, S. 677 – 690
    DOI (Open Access)
  • Westekemper, Henrike; Freistühler, Michael; Bornfeld, Norbert; Steuhl, Klaus-Peter; Scheulen, Max Ernst; Hilger, Ralf A.
    Chemosensitivity of conjunctival melanoma cell lines to target-specific chemotherapeutic agents
    In: Graefes Archive for Clinical and Experimental Ophthalmology, Jg. 251, 2013, Nr. 1, S. 279 – 284
    DOI
  • Mohn, C.; Häcker, H.-G.; Hilger, Ralf A.; Gütschow, M.; Jaehde, U.
    Defining the role of MRP-mediated efflux and glutathione in detoxification of oxaliplatin
    In: Die Pharmazie, Jg. 68, 2013, Nr. 7, S. 622 – 627
    DOI (Open Access)
  • Barr, Martin P.; Gray, Steven G.; Hoffmann, Andreas-Claudius; Hilger, Ralf A.; Thomale, Jürgen; O'Flaherty, John D.; Fennell, Dean A.; Richard, Derek; O'Leary, John J.; O'Byrne, Kenneth J.
    Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature
    In: PLoS ONE, Jg. 8, 2013, Nr. 1, e54193
    DOI (Open Access)
  • Wolf, Robert J.; Hilger, Ralf A.; Hoheisel, Jörg D.; Werner, Jens; Holtrup, Frank
    In Vivo Activity and Pharmacokinetics of Nemorosone on Pancreatic Cancer Xenografts
    In: PLoS ONE, Jg. 8, 2013, Nr. 9, S. e74555
    DOI (Open Access)
  • Jaehde, U.; Hilger, Ralf A.; Gauler, Thomas; Sehrt, D.
    The 10th Annual Meeting of CESAR in Essen June 28 – 30, 2012, Germany
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 51, 2013, Nr. 1, S. 34
    DOI
  • Lutscher, N.; Hones, S.; Grubert, M.; Scheulen, Max Ernst; Hilger, Ralf A.
    Antitumoral Activity of a New Class of Triazenes
    In: European Journal of Cancer (EJC), Jg. 48, 2012, Nr. Suppl. 6, S. 27 – 28
  • Westekemper, Henrike; Freistühler, Michael; Anastassiou, Gerasimos; Nareyeck, Gordon; Bornfeld, Norbert; Steuhl, Klaus-Peter; Scheulen, Max Ernst; Hilger, Ralf A.
    Chemosensitivity of conjunctival melanoma cell lines to single chemotherapeutic agents and combinations
    In: British Journal of Ophthalmology (BJO), Jg. 96, 2012, Nr. 4, S. 591 – 596
    DOI
  • Scheulen, Max Ernst; Saito, Kaku; Hilger, Ralf A.; Mende, Bastian; Zergebel, Christopher; Strumberg, Dirk
    Effect of food and a proton pump inhibitor on the pharmacokinetics of S-1 following oral administration of S-1 in patients with advanced solid tumors
    In: Cancer Chemotherapy and Pharmacology, Jg. 69, 2012, Nr. 3, S. 753 – 761
    DOI
  • Fichtner, Iduna; Cinatl Jr., Jindrich; Michaelis, Martin; Sanders, Lara C.; Hilger, Ralf A.; Kennedy, Breandan N.; Reynolds, Alison L.; Hackenberg, Frauke; Lally, Grainne; Quinn, Susan J.; McRae, Ian; Tacke, Matthias
    In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1
    In: Letters in Drug Design & Discovery, Jg. 9, 2012, Nr. 9, S. 815 – 822
    DOI
  • Bauer, Sebastian; Hilger, Ralf A.; Grabellus, Florian; Nagarajah, James; Hoiczyk, M.; Reichardt, A.; Ahrens, M.; Pink, D.; Mühlenberg, Thomas; Scheulen, Max Ernst; Schuler, Martin; Reichardt, P.
    Phase I trial of panobinostat (P) and imatinib (IM) in patients with treatment-refractory gastrointestinal stromal tumors (GIST)
    In: Journal of Clinical Oncology (JCO), Jg. 30, 2012, Nr. Suppl. 15, S. 10032
  • Strumberg, Dirk; Schultheis, Beate; Scheulen, Max Ernst; Hilger, Ralf A.; Krauss, J.; Marschner, N.; Lordick, F.; Bach, F.; Reuter, D.; Edler, L.; Mross, K.
    Phase II study of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer
    In: Investigational New Drugs: The Journal of New Anticancer Agents, Jg. 30, 2012, Nr. 3, S. 1138 – 1143
    DOI
  • Beier, R.; Hilger, Ralf A.; Sedlacek, P.; Greil, J.; Sauer, M.; Sykora, K. W.
    Treosulfan pharmacology in children : results of a feasibility study
    In: Bone Marrow Transplantation, Jg. 47, 2012, Nr. S1, S.S 41 - S42
  • Hendrayana, Tomi; Kurth, Verena; Krolop, Linda; Kenny, Paul; Hilger, Ralf A.; Schmidt-Wolf, Ingo G. H.; Ko, Yon-Dschun; Jaehde, Ulrich
    Variability in fluorouracil exposure during continuous intravenous infusion
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 50, 2012, Nr. 1, S. 82 – 84
    DOI
  • Hilger, Ralf A.; Wegener, T.; Richly, Heike; Lutscher, N.; Ludwig, G.; Mross, K.; Scheulen, Max Ernst
    A clinical phase I study evaluating tolerability and pharmacokinetics (PK) of TriN 2755 in patients (pts) with advanced solid tumors : A study in cooperation with the Central European Society for Anticancer Drug Research (CESAR-EWIV)
    In: Onkologie, Jg. 34, 2011, Nr. Suppl. 6, S. 109 – 110
  • Westekemper, Henrike; Freistühler, Michael; Anastassiou, Gerasimos; Nareyeck, G.; Zeschnigk, Michael; Bornfeld, Norbert; Steuhl, Klaus-Peter; Scheulen, Max Ernst; Hilger, Ralf A.
    Chemosensitivity of conjunctival melanoma cell lines to chemotherapeutic agents
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 49, 2011, Nr. 1, S. 78 – 80
  • Nemecek, Eneida R.; Guthrie, Katherine A.; Sorror, Mohamed L.; Wood, Brent L.; Doney, Kristine C.; Hilger, Ralf A.; Scott, Bart L.; Kovacsovics, Tibor J.; Maziarz, Richard T.; Woolfrey, Ann E.; Bedalov, Antonio; Sanders, Jean E.; Pagel, John M.; Sickle, Eileen J.; Witherspoon, Robert; Flowers, Mary E.; Appelbaum, Frederick R.; Deeg, H. Joachim
    Conditioning with Treosulfan and Fludarabine followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
    In: Biology of Blood and Marrow Transplantation, Jg. 17, 2011, Nr. 3, S. 341 – 350
    DOI, Online Volltext (Open Access)
  • Holtrup, Frank; Bauer, Andrea; Fellenberg, Kurt; Hilger, Ralf A.; Wink, Michael; Hoheisel, Jörg D.
    Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR)
    In: British Journal of Pharmacology (BJP), Jg. 162, 2011, Nr. 5, S. 1045 – 1059
    DOI, Online Volltext (Open Access)
  • Küpper, Uta; Musshoff, Frank; Hilger, Ralf A.; Herbstreit, Frank; Madea, Burkhard
    Pharmacokinetic Properties of Succinylmonocholine in Surgical Patients
    In: Journal of Analytical Toxicology, Jg. 35, 2011, Nr. 5, S. 302 – 311
    DOI
  • Wittig, Andrea; Stecher-Rasmussen, Finn; Hilger, Ralf A.; Rassow, Jürgen; Mauri, Pierluigi; Sauerwein, Wolfgang
    Sodium mercaptoundecahydro-closo-dodecaborate (BSH), a boron carrier that merits more attention
    In: Applied Radiation and Isotopes, Jg. 69, 2011, Nr. 12, S. 1760 – 1764
    DOI
  • Kraff, S.; Feiss, G.; Jorger, M.; Salamone, S. J.; Moritz, B.; Roessler, M.; Hilger, Ralf A.; Huitema, A.; Schellens, JHM; Jaehde, U.
    Therapeutic drug monitoring of paclitaxel in solid cancer patients : a simulation study of pharmacokinetically based dose adaptation
    In: Therapeutic Drug Monitoring, Jg. 33, 2011, Nr. 4, S. 550 – 550
  • Hilger, Ralf A.; Alex, Dennis; Deally, Anthony; Gleeson, Brendan; Tacke, Matthias
    Titanocene Y and Vanadocene Y : Platinum Resistance-Breaking Cytotoxic and DNA-Targeting Anticancer Drug Candidates
    In: Letters in Drug Design & Discovery, Jg. 8, 2011, Nr. 10, S. 904 – 910
    DOI
  • Hendrayana, T.; Kenny, P.; Hilger, Ralf A.; Schmidt-Wolf, I.; Ko, Y. D.; Jaehde, U.
    Variability of systemic fluorouracil (5-FU) exposure during continuous infusion : there is a need for TDM
    In: Therapeutic Drug Monitoring, Jg. 33, 2011, Nr. 4, S. 548 – 548
  • Westekemper, Henrike; Akgül, Harun; Scharifi, M.; Anastassiou, Gerasimos; Nareyeck, G.; Freistühler, Michael; Zeschnigk, Michael; Lohmann, Dietmar; Bornfeld, Norbert; Steuhl, Klaus-Peter; Scheulen, Max Ernst; Hilger, Ralf A.
    Chemosensitivity of conjunctival melanoma cell lines
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie, Jg. 33, 2010, Nr. Suppl. 6, S. 66
    DOI
  • Strumberg, Dirk; Schultheis, B.; Scheulen, Max Ernst; Hilger, Ralf A.; Krauss, J.; Marschner, N.; Lordick, F.; Bach, F.; Reuter, D.; Edler, L.; Mross, K.
    Safety, efficacy and pharmacokinetics of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer
    In: International Journal of Clinical Pharmacology and Therapeutics, Jg. 48, 2010, Nr. 7, S. 473 – 475
    DOI
  • Braun, Ada Henrike; Stark, Katrin; Dirsch, Olaf; Hilger, Ralf A.; Seeber, Siegfried; Vanhoefer, Udo Joachim
    The epidermal growth factor receptor tyrosine kinase inhibitor gefitinib sensitizes colon cancer cells to irinotecan
    In: Anti-Cancer Drugs, Jg. 16, 2005, Nr. 10, S. 1099 – 1108
    DOI
  • Bojko, P.; Hilger, Ralf A.; Ruehm, S.G.; Dirsch, O.; Seeber, S.; Scheulen, Max Ernst
    Femoral head necrosis in three patients with relapsed ovarian cancer receiving high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation
    In: Bone Marrow Transplantation, Jg. 31, 2003, Nr. 6, S. 487 – 491
    DOI (Open Access)

    • Abstracts

  • Hackett, David; McGrath, Jason; Lin, Xuehua; Van Acken, David; Hilger, Ralf A.; Cahill, Christina; Maher, Stephen G.
    Therapeutic targeting of microRNA-31 promotes chemosensitivity via ATOX1 in pancreatic ductal adenocarcinoma
    In: Molecular Cancer Therapeutics. Philadelphia: American Association for Cancer Research (AACR), Jg. 24, 2025, Nr. 10 (Supplement), C100
    DOI (Open Access)
  • Groß, E.; Hilger, Ralf A.; Wehde, J.; Schümann, F. L.; Rohde, C.; Willscher, E.; Lützkendorf, J.; Müller, L. P.; Edemir, B.; Müller, T.; Binder, M.; Posern, G.; Weber, T.
    EZH2 Inhibitoren vermitteln Platinresistenz durch verstärkten Efflux
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 45, 2022, Nr. Supplement 2, S. 41
    DOI (Open Access)
  • Wichmann, Catharina; Kuhlmann, Jan Dominik; Klotz, Daniel Martin; Zeiler, Hans-Joachim; Hilger, Ralf; Wimberger, Pauline
    The effect of the triazene compound CT913 on ovarian cancer cells in vitro and its interaction with PARP-inhibitors
    XXIX. Wissenschaftliche Tagung der Arbeitsgemeinschaft für gynäkologische Onkologie (AGO) der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG) und 18. Österreichischer Kongress „Krebs bei der Frau“, 15.-17.04.2021, Virtuell,
    In: Geburtshilfe und Frauenheilkunde. Stuttgart: Thieme, Jg. 81, 2021, Nr. 6, S. E38 – E38
    DOI
  • Joerger, M.; Salamone, S. J.; von Pawel, J.; Kraff, S.; Fischer, J. R.; Eberhardt, Wilfried; Gauler, Thomas; Muller, L.; Reinmuth, N.; Reck, M.; Kimmich, M.; Mayer, F.; Kopp, H. G.; Behringer, D. M.; Ko, Y. D.; Fruh, M.; Hilger, Ralf A.; Roessler, M.; Moritz, B.; Miller, Michael; Jaehde, U.
    Randomized study of individualized, pharmacokinetically-guided dosing of paclitaxel combined with carboplatin in advanced non-small cell lung cancer patients
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,
    In: Oncology Research and Treatment. Basel: Karger, Jg. 38, 2015, Nr. Suppl. 5, S. 14 – 14
    DOI
  • Tippelt, Stephan; Mikasch, R.; Siegler, N.; Hilger, Ralf A.; Jaehde, U.; Bode, U.; Kwiecien, R.; Faldum, A.; Fleischhack, Gudrun
    Results of Pharmacokinetic analysis of intraventricular Etoposide in a Phase II Study of Recurrent Medulloblastoma, CNS-PNET and Ependymoma
    47th Congress of the International Society of Paediatric Oncology (SIOP) Cape Town, South Africa October 8–11, 2015,
    In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 62, 2015, Nr. S 4, Abstracts From the 47th Congress of the International Society of Paediatric Oncology (SIOP) Cape Town, South Africa October 8–11, 2015, S. S284
    DOI
  • Friesen, C.; Roscher, M.; Fichtner, I.; Alt, A.; Hilger, Ralf A.; Debatin, K. M.; Miltner, E.
    Opioid receptor activation triggering downregulation of cAMP sensitizes leukemia cells for doxorubicin treatment in vitro and in vivo
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, 18.-22. Oktober 2013, Wien, Österreich,
    In: Onkologie. Basel: Karger, Jg. 36, 2013, Nr. Suppl. 7, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Wien, 18.-22. Oktober 2013: Abstracts, S. 265
    DOI
  • Scheulen, Max Ernst; Richly, Heike; Kalkavan, H.; Hoffmann, Andreas-Claudius; Virchow, I.; Hilger, Ralf A.; Koeppen, Susanne; Sure, Ulrich; Schuler, Martin; Hense, Jörg
    An investigator-initiated monocentric phase I dose escalation trial of temsirolimus and irinotecan (TEMIR) in patients with relapsing glioblastoma multiforme (reGBM)
    48th Annual Meeting of the American Society of Clinical Oncology (ASCO), June 1-5, 2012, Chicago, Ill., USA,
    In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 30, 2012, Nr. 15, Suppl., 2086
    DOI
  • Hilger, Ralf A.; Wegener, Tobias; Richly, Heike; Ludwig, Georg; Mross, Klaus; Scheulen, Max Ernst
    A phase I dose-escalation study with pharmacokinetics (PK) of TriN 2755 in patients with advanced solid tumors : A study in cooperation with the Central European Society for Anticancer Drug Research (CESAR-EWIV)
    In: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 71, 2011, Nr. 8, Suppl., S. 1293
    DOI
  • Holtrup, Frank; Wolf, Robert; Hilger, Ralf A.; Seeber, Siegfried; Hoheisel, Jörg D.
    Antitumor activity of nemorosone against pancreatic cancer cells and xenografts
    In: Cancer Research. Philadelphia: American Association for Cancer Research (AACR), Jg. 71, 2011, Nr. 8, Suppl., S. 5420 – 5420
    DOI
  • Nemecek, E. R.; Guthrie, K.; Sorror, M.; Hilger, Ralf A.; Doney, K.; Scott, B.; Kovacsovics, T.; Maziarz, R.; Woolfrey, A.; Sanders, J.; Sickle, E.; Borruel-Rector, J.; O'Donnell, P.; Witherspoon, R.; Appelbaum, F.; Deeg, H. J.
    Conditioning with treosulfan and fludarabine followed by allogeneic haematopoietic cell transplantation for high-risk haematologic malignancies. Results of a phase I/II multicentre study in the United States
    In: Bone Marrow Transplantation. London: Springer Nature, Jg. 45, 2010, Nr. Suppl. 2, S. S285

    • Poster / Posterbeiträge

  • Hilger, Ralf A.; Köhler, Jens; Kalkavan, H.; Richly, Heike; Hoffmann, Andreas-Claudius; Heinrichs, D.; Azaouagh, A.; Schuler, Martin; Trarbach, Tanja
    Interpatient pharmacokinetic variability of 5-FU within metastatic and adjuvant colon cancer patients : First results from the West German Cancer Center
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 173
    DOI