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Wiss. Mitarbeiterinnen/Mitarbeiter, Klinik für Anästhesiologie und Intensivmedizin
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SoSe 2025
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Quantification of left ventricular ejection fraction and cardiac output using a novel semi-automated echocardiographic method : a prospective observational study in coronary artery bypass patientsIn: BMC Anesthesiology, Jg. 23, 2023, Nr. 1, 65DOI (Open Access)
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Polymorphic Variants in the GRK5 Gene Promoter Are Associated With Diastolic Dysfunction in Coronary Artery Bypass Graft Surgery PatientsIn: Anesthesia & Analgesia, Jg. 134, 2022, Nr. 4, S. 858 – 868
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The Role of G Protein-Coupled Receptor Kinase 6 Regulation in Inflammation and PainIn: International Journal of Molecular Sciences (IJMS), Jg. 23, 2022, Nr. 24, 15880DOI (Open Access)
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Agony of choice : How anesthetics affect the composition and function of extracellular vesiclesIn: Advanced Drug Delivery Reviews, Jg. 175, 2021, 113813
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Characterization of the G protein-coupled receptor kinase 6 promoter reveals a functional CREB binding siteIn: PLoS ONE, Jg. 16, 2021, Nr. 2, S. e0247087DOI, Online Volltext (Open Access)
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Postoperative nausea and vomiting : The role of the serotonin transporter 5-HTTLPR polymorphismIn: European Journal of Anaesthesiology EJA, Jg. 38, 2021, Nr. 1, S. 92 – 93
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Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposureIn: PLoS ONE, Jg. 15, 2020, Nr. 2, S. e0228948DOI (Open Access)
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Genetic contribution to PONV riskIn: Anaesthesia Critical Care & Pain Medicine, Jg. 39, 2020, Nr. 1, S. 45 – 51
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Genetic variability in postoperative nausea and vomiting : A systematic reviewIn: European Journal of Anaesthesiology EJA, Jg. 37, 2020, Nr. 11, S. 959 – 968
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Genetic variations in G-protein signal pathways influence progression of coronary artery calcification : Results from the Heinz Nixdorf Recall studyIn: Atherosclerosis, Jg. 310, 2020, S. 102 – 108
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Modified implantation height of the Sapien3™ transcatheter heart valveIn: Minimally Invasive Therapy and Allied Technologies, Jg. 29, 2020, Nr. 2, S. 70 – 77
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Can a brief psychological expectancy intervention improve postoperative pain? : A randomized, controlled trial in patients with breast cancerIn: Pain, Jg. 160, 2019, Nr. 7, S. 1562 – 1571
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Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro-RNA signature in CABG patientsIn: Acta Anaesthesiologica Scandinavica, Jg. 63, 2019, Nr. 4, S. 483 – 492
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True Lumen Stabilization to Overcome Malperfusion in Acute Type I Aortic DissectionIn: Seminars in Thoracic and Cardiovascular Surgery, Jg. 31, 2019, Nr. 4, S. 740 – 748DOI (Open Access)
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CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effectiveIn: British Journal of Anaesthesia (BJA), Jg. 121, 2018, Nr. 1, S. 58 – 65DOI (Open Access)
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Circulating miR-192 is a prognostic marker in patients with ischemic cardiomyopathyIn: Future Cardiology, Jg. 14, 2018, Nr. 4, S. 283 – 289
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Establishment of an easy and straight forward heparinase protocol to analyse circulating and myocardial tissue micro-RNA during coronary artery-bypass-graft surgeryIn: Scientific Reports, Jg. 8, 2018, Nr. 1, S. 1361DOI (Open Access)
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Impact of remote ischemic preconditioning in cardiosurgical patients on contractile and mitochondrial function of right atrial tissueIn: European Heart Journal, Jg. 39, 2018, Nr. Suppl. 1, S. 453
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Improvement of mitochondrial function in human atrial tissue by remote ischemic conditioningIn: The FASEB Journal, Jg. 32, 2018, Nr. S1, S. 580.1
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Increased circulating microRNA-122 is associated with mortality and acute liver injury in the acute respiratory distress syndromeIn: BMC Anesthesiology, Jg. 18, 2018, S. 75DOI (Open Access)
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Increased circulating microrna-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteriaIn: PLoS ONE, Jg. 13, 2018, Nr. 5, S. e0197637DOI (Open Access)
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Mitochondrial and contractile function of human right atrial tissue in response to remote ischemic conditioningIn: Journal of the American Heart Association, Jg. 7, 2018, Nr. 15, S. e009540DOI (Open Access)
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Point-of-Care-Diagnostik in der Traumatologie - Methoden und EvidenzIn: AINS - Anästhesiologie Intensivmedizin Notfallmedizin Schmerztherapie, Jg. 53, 2018, Nr. 6, S. 440 – 457
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The GRK2 Promoter Is Regulated by Early-Growth Response Transcription Factor EGR-1In: Basic and Clinical Pharmacology and Toxicology (BCPT), Jg. 123, 2018, Nr. 6, S. 660 – 669
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Alarm-Fatigue - wieviel Alarm verträgt der Mensch?In: AINS - Anästhesiologie Intensivmedizin Notfallmedizin Schmerztherapie, Jg. 52, 2017, Nr. 7-8, S. 564 – 570
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Cardioprotection by Remote Ischemic Conditioning in Humans : Improved Contractile Function and Mitochondrial Respiration of Atrial TrabeculaeIn: Circulation, Jg. 136, 2017, Nr. Suppl. 1
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Comparison of mortality prediction models in acute respiratory distress syndrome undergoing extracorporeal membrane oxygenation and development of a novel prediction score: the PREdiction of Survival on ECMO Therapy-Score (PRESET-Score).In: Critical Care: The Online Intensive Care Journal, Jg. 21, 2017, Nr. 1, S. 301DOI, Online Volltext (Open Access)
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ESC Joint Working Groups on Cardiovascular Surgery and the Cellular Biology of the Heart Position Paper : Peri-operativemyocardial injury and infarction in patients undergoing coronary artery bypass graft surgeryIn: European Heart Journal, Jg. 38, 2017, Nr. 31, S. 2392 – 2411DOI (Open Access)
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GNAQ TT(-695/-694)GC Polymorphism Is Associated with Increased Gq Expression, Vascular Reactivity, and Myocardial Injury after Coronary Artery Bypass SurgeryIn: Anesthesiology, Jg. 127, 2017, Nr. 1, S. 70 – 77
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No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation : Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trialIn: International Journal of Cardiology, Jg. 231, 2017, S. 248 – 254
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Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularizationIn: Scientific Reports, Jg. 7, 2017, S. 12660DOI (Open Access)
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Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion : Remote ischemic preconditioningIn: Scientific Reports, Jg. 7, 2017, Nr. 1DOI, Online Volltext (Open Access)
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Easy-to-use strategy for reference gene selection in quantitative real-time PCR experimentsIn: Naunyn-Schmiedeberg's Archives of Pharmacology, Jg. 389, 2016, Nr. 12, S. 1353 – 1366
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Postoperative nausea and vomiting : The role of the dopamine D2 receptor TaqIA polymorphismIn: European Journal of Anaesthesiology EJA, Jg. 33, 2016, Nr. 2, S. 84 – 89
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Characterization of the PLCB1 promoter and regulation by early growth response transcription factor EGR-1In: European Journal of Pharmacology, Jg. 742, 2014, Nr. 5, S. 8 – 14
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GNAS Gene Variants Affect β-blocker–related Survival after Coronary Artery Bypass GraftingIn: Anesthesiology, Jg. 120, 2014, Nr. 5, S. 1109 – 1117DOI, Online Volltext (Open Access)
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GNB3 gene 825 TT variant predicts hard coronary events in the population-based Heinz Nixdorf Recall studyIn: Atherosclerosis, Jg. 237, 2014, Nr. 2, S. 437 – 442
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Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic ShockIn: PLoS ONE, Jg. 9, 2014, Nr. 8, e104953DOI (Open Access)
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Myocardial protection by remote ischaemic pre-conditioning is abolished in sulphonylurea-treated diabetics undergoing coronary revascularisationIn: Acta Anaesthesiologica Scandinavica, Jg. 58, 2014, Nr. 4, S. 453 – 462
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The haplotype of three polymorphisms in the SATB1 promoter region impacts survival in breast cancer patientsIn: Oncology Letters, Jg. 7, 2014, Nr. 6, S. 2007 – 2012DOI, Online Volltext (Open Access)
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The minimally invasive MitraClip(TM) procedure for mitral regurgitation under general anaesthesia : immediate effects on the pulmonary circulation and right ventricular functionIn: Anaesthesia, Jg. 69, 2014, Nr. 8, S. 860 – 867DOI (Open Access)
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β2-Adrenoceptor gene variants affect vasopressor requirements in patients after thoracic epidural anaesthesiaIn: British Journal of Anaesthesia (BJA), Jg. 112, 2014, Nr. 3, S. 477 – 484DOI (Open Access)
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Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulatedIn: Shock, Jg. 40, 2013, Nr. 5, S. 430 – 436
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Cloning and characterization of the GNA11 promoter and its regulation by early growth response 1In: Basic and Clinical Pharmacology and Toxicology (BCPT), Jg. 113, 2013, Nr. 5, S. 316 – 324
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Decreased expression of miR-133a but not of miR-1 is associated with signs of heart failure in patients undergoing coronary bypass surgeryIn: Cardiology, Jg. 125, 2013, Nr. 2, S. 125 – 130
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The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.In: Anesthesiology, Jg. 118, 2013, Nr. 1, S. 123 – 133
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The functional Aquaporin 1 −783G/C-polymorphism is associated with survival in patients with glioblastoma multiformeIn: Journal of Surgical Oncology, Jg. 108, 2013, Nr. 7, S. 492 – 498
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The GNB3 C825T polymorphism influences platelet aggregation in human whole bloodIn: Pharmacogenetics and Genomics, Jg. 22, 2012, Nr. 1, S. 43 – 49
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Aquaporin 5 gene promoter -1364A/C polymorphism associated with 30-day survival in severe sepsisIn: Anesthesiology, Jg. 114, 2011, Nr. 4, S. 912 – 917DOI (Open Access)
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Characterization of the GNA11 promoter and regulation by Egr-1In: Naunyn-Schmiedeberg's Archives of Pharmacology, Jg. 383, 2011, Nr. Suppl. 1, S. 29 – 30
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Comparison of Thrombelastometry with Simplified Acute Physiology Score II and Sequential Organ Failure Assessment Scores for the Prediction of 30-Day Survival : A Cohort StudyIn: Shock, Jg. 35, 2011, Nr. 4, S. 339 – 342DOI (Open Access)
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Genetic interactions in the β-adrenoceptor/G-protein signal transduction pathway and survival after coronary artery bypass grafting : a pilot studyIn: British Journal of Anaesthesia (BJA), Jg. 107, 2011, Nr. 6, S. 869 – 878DOI (Open Access)
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Role of the GNAS1 T393C polymorphism in patients with glioblastoma multiformeIn: Journal of Clinical Neuroscience, Jg. 18, 2011, Nr. 11, S. 1495 – 1499
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The NFKB1 promoter polymorphism (94ins/delATTG) alters nuclear translocation of NF-KB1 in monocytes following lipopolysaccharide stimulation and is associated with increased mortality in sepsisIn: Infection - A Journal of Infectious Disease, Jg. 39, 2011, Nr. Suppl. 2, S. 102
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Transfemoral aortic valve implantation under sedation and monitored anaesthetic care : a feasibility studyIn: Anaesthesia, Jg. 66, 2011, Nr. 11, S. 977 – 982
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A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndromeIn: Pharmacogenetics and Genomics, Jg. 20, 2010, Nr. 8, S. 476 – 484
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Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiformeIn: Journal of Cancer Research and Clinical Oncology, Jg. 136, 2010, Nr. 9, S. 1423 – 1429
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The Arg16Gly-β2-adrenoceptor single nucleotide polymorphism : exercise capacity and survival in patients with end-stage heart failureIn: Naunyn-Schmiedeberg's Archives of Pharmacology, Jg. 382, 2010, Nr. 4, S. 357 – 365
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The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levelsIn: European Journal of Haematology, Jg. 85, 2010, Nr. 2, S. 108 – 113
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A novel promoter polymorphism in the human gene GNAS affects binding of transcription factor upstream stimulatory factor 1, Gαs protein expression and body weight regulationIn: Pharmacogenetics and Genomics, Jg. 18, 2008, Nr. 2, S. 141 – 151
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A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy menIn: Basic Research in Cardiology, Jg. 103, 2008, Nr. 6, S. 598 – 610
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Association study of the G-protein β3 subunit C825T polymorphism with disease progression an overall survival in patients with head and neck squamous cell carcinomaIn: Cancer Epidemiology, Biomarkers & Prevention, Jg. 17, 2008, Nr. 11, S. 3203 – 3207DOI (Open Access)
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Erythropoietin treatment improves liver regeneration and survival in rat models of extended liver resection and living donor liver transplantationIn: Transplantation, Jg. 86, 2008, Nr. 11, S. 1578 – 1585
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Factor v Leiden mutation is associated with improved 30-day survival in patients with acute respiratory distress syndromeIn: Critical Care Medicine, Jg. 36, 2008, Nr. 6, S. 1776 – 1779
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The GNAS1 T393C polymorphism predicts survival in patients with advanced squamous cell carcinoma of the larynxIn: Laryngoscope, Jg. 118, 2008, Nr. 12, S. 2172 – 2176
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GNAS1 T393C polymorphism is associated with clinical course in patients with intrahepatic cholangiocarcinomaIn: Neoplasia: An International Journal for Oncology Research, Jg. 9, 2007, Nr. 2, S. 159 – 165DOI (Open Access)
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The C allele of the GNB3 C825T polymorphism of the G protein β3-subunit is associated with an increased risk for the development of oncocytic thyroid tumoursIn: The Journal of Pathology, Jg. 211, 2007, Nr. 1, S. 60 – 66
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The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinomaIn: Breast Cancer Research and Treatment, Jg. 105, 2007, Nr. 3, S. 311 – 317
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The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinomaIn: Clinical Cancer Research, Jg. 12, 2006, Nr. 3, S. 759 – 763DOI (Open Access)
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GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancerIn: Clinical Cancer Research, Jg. 11, 2005, Nr. 14, S. 5071 – 5077DOI (Open Access)
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The T393C polymorphism of the Gαs gene (GNAS1) is a novel prognostic marker in bladder cancerIn: Cancer Epidemiology, Biomarkers & Prevention, Jg. 14, 2005, Nr. 4, S. 871 – 877DOI (Open Access)
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Quantification of G protein Gαs subunit splice variants in different human tissues and cells using pyrosequencingIn: Gene Expression, Jg. 12, 2004, Nr. 2, S. 69 – 81DOI (Open Access)
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Association of HLA-G Haplotype Risk Model with Treatment Free Survival In Chronic Lymphocytic Leukemia PatientsIn: Blood. Washington; New York, NY [u.a.]; Philadelphia, Pa.: American Society of Hematology, Jg. 116, 2010, Nr. 21, S. 1002 – 1003
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Association of HLA-G haplotype risk model with treatment free survival in chronic lymphocytic leukemia patients
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, Berlin, Oktober 2010,In: Onkologie. Basel: Karger, Jg. 33, 2010, Nr. Suppl. 6, S. 45 -
The functional GNAQ promoter polymorphism TT(-695/-694) GC is associated with increased cardiac output in healthy subjects and patients with coronary artery disease
51th Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie Mainz, March 23 – 25, 2010,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 381, 2010, Nr. Suppl. 1, S. 87 -
Auswirkung funktionell wirksamer Polymoriphismen im β- adrenergen Signaltransduktionsweg auf Gen- und Proteinexpression sowie perioperative Hämodynamik, Myokardschädigung und PrognoseDuisburg, Essen, 2011