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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Corrigendum to “European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescence”In: EJC Paediatric Oncology, Jg. 6, 2025, 100305DOI (Open Access)
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Distinct relapse pattern across molecular ependymoma typesIn: Neuro-Oncology, Jg. 27, 2025, Nr. 1, S. 267 – 276
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European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescenceIn: EJC Paediatric Oncology, Jg. 5, 2025, 100227DOI (Open Access)
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Molecular characterization and clinical features of diffuse midline glioma in the pediatric precision oncology registry INFORMIn: Acta Neuropathologica, Jg. 150, 2025, Nr. 1, 42DOI (Open Access)
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Pediatric spinal high-grade glioma in the pediatric precision oncology registry INFORM : Identification of potential therapeutic targetsIn: Neuro-Oncology Advances, Jg. 7, 2025, Nr. 1, vdae185DOI (Open Access)
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Recurrence patterns in pediatric intracranial ependymal neoplasm : A systematic imaging work-upIn: Neuroradiology, Jg. 67, 2025, Nr. 3, S. 767 – 781DOI (Open Access)
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Impact of molecular classification on prognosis in children and adolescents with spinal ependymoma : Results from the HIT-MED databaseIn: Neuro-Oncology Advances, Jg. 6, 2024, Nr. 1, vdae179DOI (Open Access)
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Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORMIn: JCO Precision Oncology, Jg. 7, 2024, e2300015DOI (Open Access)
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Radiotherapy and long-term sequelae in pediatric patients with parameningeal rhabdomyosarcoma: Results of two Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registryIn: Pediatric Blood and Cancer, Jg. 71, 2024, Nr. 1, e30742DOI (Open Access)
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Radiotherapy for Recurrent Medulloblastoma in Children and Adolescents : Survival after Re-Irradiation and First-Time IrradiationIn: Cancers, Jg. 16, 2024, Nr. 11, 1955DOI, Online Volltext (Open Access)
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Significance of fusion status, Oberlin risk factors, local and maintenance treatment in pediatric and adolescent patients with metastatic rhabdomyosarcoma : Data of the European Soft Tissue Sarcoma Registry SoTiSaRIn: Pediatric Blood and Cancer, Jg. 71, 2024, Nr. 1, e30707DOI (Open Access)
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3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymomaIn: Nature Communications, Jg. 14, 2023, Nr. 1, 2300DOI (Open Access)
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Kinder und Jugendliche mit intrakraniellem Ependymom : Empfehlungen der HIT-MED-Studiengruppe der GPOH zur ErstlinientherapieIn: Klinische Pädiatrie, Jg. 235, 2023, Nr. 3, S. 167 – 177
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Second-line treatment of pediatric patients with relapsed rhabdomyosarcoma adapted to initial risk stratification : Data of the European Soft Tissue Sarcoma Registry (SoTiSaR)In: Pediatric Blood and Cancer, Jg. 70, 2023, Nr. 7, e30363DOI (Open Access)
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The significance of margins in pediatric Non-Rhabdomyosarcoma soft tissue sarcomas : Consensus on surgical margin definition harmonization from the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT)In: Cancer Medicine, Jg. 12, 2023, Nr. 10, S. 11719 – 11730DOI (Open Access)
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The Current Landscape of Targeted Clinical Trials in Non-WNT/Non-SHH MedulloblastomaIn: Cancers, Jg. 14, 2022, Nr. 3, 679DOI (Open Access)
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Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial EpendymomasIn: Cancer Discovery, Jg. 11, 2021, Nr. 9, S. 2230 – 2247DOI, Online Volltext (Open Access)
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Local and systemic therapy of recurrent ependymoma in children and adolescents : Short- and long-term results of the E-HIT-REZ 2005 studyIn: Neuro-Oncology, Jg. 23, 2021, Nr. 6, S. 1012 – 1023DOI, Online Volltext (Open Access)
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Sarcoma classification by DNA methylation profilingIn: Nature Communications, Jg. 12, 2021, Nr. 1, S. 498DOI (Open Access)
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Systemic chemotherapy of pediatric recurrent ependymomas : results from the German HIT-REZ studiesIn: Journal of Neuro-Oncology, Jg. 155, 2021, Nr. 2, S. 193 – 202DOI (Open Access)
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The Pediatric Precision Oncology INFORM Registry : Clinical Outcome and Benefit for Patients with Very High-Evidence TargetsIn: Cancer Discovery, Jg. 11, 2021, Nr. 11, S. 2764 – 2779DOI (Open Access)
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The genetic landscape of choroid plexus tumors in children and adultsIn: Neuro-Oncology, Jg. 23, 2021, Nr. 4, S. 650 – 660DOI, Online Volltext (Open Access)
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Newly Diagnosed Metastatic Intracranial Ependymoma in Children : Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT SeriesIn: The Oncologist, Jg. 24, 2019, Nr. 7DOI (Open Access)
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DNA methylation-based classification of central nervous system tumoursIn: Nature, Jg. 555, 2018, Nr. 7697, S. 469 – 474DOI (Open Access)
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FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytomaIn: Acta Neuropathologica, Jg. 136, 2018, Nr. 2, S. 293 – 302DOI (Open Access)
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Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohortIn: The Lancet Oncology, Jg. 19, 2018, Nr. 6, S. 785 – 798DOI (Open Access)
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The landscape of genomic alterations across childhood cancersIn: Nature, Jg. 555, 2018, Nr. 7696, S. 321 – 327DOI (Open Access)
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Childhood cancer predisposition syndromes : A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and HematologyIn: American Journal of Medical Genetics, Part A, Jg. 173, 2017, Nr. 4, S. 1017 – 1037
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The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma modelsIn: OncoTarget, Jg. 8, 2017, Nr. 4, S. 6730 – 6741DOI (Open Access)
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Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumorsIn: Journal of Neuro-Oncology, Jg. 128, 2016, Nr. 3, S. 463 – 471
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MiR-34a deficiency accelerates medulloblastoma formation in vivoIn: International Journal of Cancer, Jg. 136, 2015, Nr. 10, S. 2293 – 2303DOI (Open Access)
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Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age GroupsIn: Cancer Cell, Jg. 27, 2015, Nr. 5, S. 728 – 743DOI (Open Access)
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Neuroblastoma in dialog with its stroma : NTRK1 is a regulator of cellular cross-talk with Schwann cellsIn: OncoTarget, Jg. 5, 2014, Nr. 22, S. 11180 – 11192DOI (Open Access)
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Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cellsIn: International Journal of Cancer, Jg. 133, 2013, Nr. 4, S. 908 – 919
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Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiationIn: Leukemia, Jg. 26, 2012, Nr. 9, S. 2039 – 2051
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Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomasIn: Neuro-Oncology, Jg. 14, 2012, Nr. 7, S. 859 – 869DOI (Open Access)
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The role of local Therapy in recurrent Ependymoma : A Report of the E-Hit-REZ-2005 StudyIn: Neuro-Oncology, Jg. 14, 2012, Nr. 1, S. 37
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High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary NeuroblastomaIn: Clinical Cancer Research, Jg. 17, 2011, Nr. 15, S. 5082 – 5092
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Pharmacological activation of the p53 pathway by nutlin-3 inhibits medulloblastoma cell proliferation in vitro and in vivoIn: European Journal of Pediatrics, Jg. 170, 2011, Nr. 2, S. 267 – 268
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Viscum Album (mistletoe) extract inhibits growth of pediatric tumor cells in vitroIn: Klinische Pädiatrie, Jg. 223, 2011, Nr. 3, S. 198
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Viscum album inhibits cell growth, migration and invasion of pediatric tumor cell lines - But effects are limited at concentrations found in serumIn: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, Jg. 18, 2011, Nr. Suppl. 8, S. 8 – S9
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Accurate prediction of neuroblastoma outcome based on miRNA expression profilesIn: International Journal of Cancer, Jg. 127, 2010, Nr. 10, S. 2374 – 2385
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LSD1 is a novel therapeutic target in neuroblastoma (NB) and medulloblastoma (MB)In: European Journal of Pediatrics, Jg. 169, 2010, Nr. 3, S. 381
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Production of chick embryo extract for the cultivation of murine neural crest stem cellsIn: JoVE, Jg. 2010, 2010, Nr. 45DOI, Online Volltext (Open Access)
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ALK Mutation Analysis in Patients of the German Neuroblastoma StudyIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 195
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LSD 1 is a Potential Therapeutic Target in MedulloblastomaIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 203 – 204
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Lysine-Specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : Implications for therapyIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. A61
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Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapyIn: Cancer Research, Jg. 69, 2009, Nr. 5, S. 2065 – 2071DOI (Open Access)
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Expression of TrkA is a potential regulator of immunogenicity in neuroblastoma cellsIn: Klinische Pädiatrie, Jg. 218, 2006, Nr. 3, S. 192 – 192
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Author Correction : The landscape of genomic alterations across childhood cancersIn: Nature. London: Springer Nature, Jg. 559, 2018, Nr. 7714, S. E10
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Distinct Relapse Pettern across Molecular Ependymoma TypesIn: Neuro-Oncology. Oxford: Oxford University Press, Jg. 26, 2024, Nr. Supplement_4DOI (Open Access)
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Impact of Molecular Subtyping on Prognosis in Children and Adolescents with Spinal EpendymomaIn: Neuro-Oncology. Oxford: Oxford University Press, Jg. 26, 2024, Nr. Supplement_4DOI (Open Access)
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Molecular Markers and Predisctors of Outcome for Paediatric Intracranial Eoendymoma in the Prospective, Multicentre E-Hit 2000 Trial and Subsequent Hit-Registries : A Pooled Analysis of 244 Patients
21st International Symposium on Pediatric Neuro-Oncology (ISPNO 2024) , 28 June – 2 July 2024, Philadelphia,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 26, 2024, Nr. Supplement_4: Abstracts from the 2024 International Symposium on Pediatric Neuro-Oncology (ISPNO)DOI (Open Access) -
P20.16.B First-line treatment of medulloblastoma in adolescents and adults : Update on the EORTC 1634-btg/noa-23 phase II trialIn: Neuro-Oncology. Oxford: Oxford University Press, Jg. 25, 2023, Nr. Suppl. 2, S. ii130 – ii131DOI, Online Volltext (Open Access)
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EPEN-19. Impact of molecular classification on prognosis in children and adolescents with spinal ependymoma: Results from the HIT-MED database
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i42DOI (Open Access) -
MEDB-38. Significance of CSF cytology and neurologic deterioration in relapsed medulloblastomas in the German HIT-REZ-97/-2005 Studies and the HIT-REZ-Register
20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022),In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 24, 2022, Nr. Supplement_1: Abstracts from the 20th International Symposium on Pediatric Neuro-Oncology (ISPNO 2022), S. i113 – i114DOI (Open Access) -
Chemotherapy of recurrent ependymoma : Long term response only in few cases
19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), 13.-16.12.2020, Karuizawa, Japan,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 22, 2020, Nr. Supplement_3: Abstracts from the 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), S. iii309DOI (Open Access) -
Chromosome 1q Gain in Recurrent PF-A Ependymoma Predicts Worse Outcome after First Relapse
52th Congress of the International Society of Paediatric Oncology (SIOP) Virtual Congress, 14.-17.10.2020, Ottawa, Canada,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 67, 2020, Nr. S4, S. S302 – S303DOI (Open Access) -
Clinical stratified treatment of localized pediatric intracranial ependymoma with combined local irradiation and chemotherapy within the prospective, multicenter E-Hit trial : the molecular subgroup matters
19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020); December 13 - 16, 2020; Karuizawa, Japan,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 22, 2020, Nr. Supplement_3, S. iii315 – iii316DOI (Open Access) -
Impact of the molecular subgroup on outcome for infants < 12 months with intracranial ependymoma : German experience from HIT 2000, Interim-2000-Registry and I-HIT-MED Registry
19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), 13.-16.12.2020, Karuizawa, Japan,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 22, 2020, Nr. Supplement_3: Abstracts from the 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), S. iii309DOI (Open Access) -
Peds : Pediatric ependymoma discovery study
19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), 13.-16.12.2020, Karuizawa, Japan,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 22, 2020, Nr. Supplement_3: Abstracts from the 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), S. iii317DOI (Open Access) -
The pediatric precision oncology study INFORM : Clinical outcome and benefit for molecular subgroups
2020 ASCO Annual Meeting; 29.05.2020 - 02.06.2020; Chicago, USA,In: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 38, 2020, Nr. Suppl. 18, S. LBA10503DOI (Open Access) -
Soluble NKG2DL are released by Tumor Cell Lines in a Mutually exclusive fashion as free Molecules or via extracellular vesicles
28th EFI European Immunogenetics and Histocompatibility Conference Stockholm, Sweden, June 25th–28th, 2014,In: Tissue Antigens. Oxford: Wiley-Blackwell, Jg. 84, 2014, Nr. 1, S. 17 – 18 -
Lysin-Specific Histone Dementhylase 1(LSD1) is a promising new Epigenetic Theapy target Crucially involved in the migration of Medulloblastoma Cells
15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 14, 2012, Nr. Suppl. 1, S. i92 -
miR-34a is dispensable for normal development but its loss Accelerates medulloblastoma formation
15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada,In: Neuro-Oncology. Oxford: Oxford University Press, Jg. 14, 2012, Nr. Suppl. 1, S. 89 -
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 812 -
High Expression of the alk Receptor Tyrosine Kinase Precedes Mutation as a Determining Factor of Unfavourable Phenotype in Primary Neuroblastoma
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 827 -
Pharmacologic Activation of the P53 Pathway by Nutlin-3 Inhibits Medulloblastoma Cell Proliferation in Vitro
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 918 -
LSD1 is a Potential Therapeutic Target in Medulloblastoma
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, October 5–9, 2009, Sao Paulo, Brazil,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 826 -
Modeling Neuroblastomagenesis from neural crest Stem Cells in Vitro and in Vivo
41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 53, 2009, Nr. 5, S. 703 – 704 -
Analyse der Interaktion Trk-Rezeptor tragender Neuroblastomzellen mit Zellen des Immunsytems und mit SchwannzellenDuisburg, Essen, 2010