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Institut für Immunologie der Medizinischen Fakultät der Universität Duisburg-Essen
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45122 Essen
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Direktor/in, Institut für Immunologie
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SoSe 2025
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WiSe 2024
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SoSe 2024
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WiSe 2023
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphomaIn: Nature Communications , Jg. 16 2025, Nr. 1, 4967DOI (Open Access)
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Immune training enhances anti-viral responses and improves outcomes in Pax5−/⁺ mice susceptible to chronic infectionIn: EMBO Molecular Medicine , Jg. 17 2025, Nr. 4, S. 696 – 721DOI (Open Access)
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Patrolling monocytes mediate virus neutralizing IgG effector functions : beyond neutralization capacityIn: Frontiers in Immunology , Jg. 16 2025, 1600056DOI (Open Access)
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High-Affinity–Mediated Viral Entry Triggers Innate Affinity Escape Resulting in Type I IFN Resistance and Impaired T Cell ImmunityIn: The Journal of Immunology (JI) , Jg. 212 2024, Nr. 9, S. 1457 – 1466DOI (Open Access)
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Increased Risk for Infections and Allergic Disease in Hereditary Hemorrhagic TelangiectasiaIn: Journal of Clinical Medicine (JCM) , Jg. 13 2024, Nr. 13, 3752DOI, Online Volltext (Open Access)
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Interleukin 1 β suppresses bile acid-induced BSEP expression via a CXCR2-dependent feedback mechanismIn: PLoS ONE , Jg. 19 2024, Nr. 12, e0315243DOI (Open Access)
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Natural IgG protects against early dissemination of vesicular stomatitis virusIn: Journal of Autoimmunity , Jg. 146 2024, 103230DOI (Open Access)
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Sphingosine Prevents Rhinoviral InfectionsIn: International Journal of Molecular Sciences (IJMS) , Jg. 25 2024, Nr. 5, 2486DOI, Online Volltext (Open Access)
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Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis PatientsIn: Cells , Jg. 12 2023, Nr. 14, 1892DOI, Online Volltext (Open Access)
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Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infectionsIn: PLoS Pathogens , Jg. 19 2023, Nr. 11, e1011837DOI (Open Access)
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Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumorsIn: Molecular Cancer , Jg. 22 2023, Nr. 1, 136DOI (Open Access)
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Usp22 Deficiency Leads to Downregulation of PD-L1 and Pathological Activation of CD8⁺ T Cells and Causes Immunopathology in Response to Acute LCMV InfectionIn: Vaccines , Jg. 11 2023, Nr. 10, 1563DOI (Open Access)
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BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor MicroenvironmentIn: Cancer Research , Jg. 82 2022, Nr. 2, S. 264 – 277DOI (Open Access)
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Communicator-Driven Data Preprocessing Improves Deep Transfer Learning of Histopathological Prediction of Pancreatic Ductal AdenocarcinomaIn: Cancers , Jg. 14 2022, Nr. 8, 1964DOI (Open Access)
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During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodesIn: Cell Reports , Jg. 40 2022, Nr. 7, 111171DOI (Open Access)
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Immune suppression of vaccine-induced CD8⁺ T cell-responses by gamma retrovirus envelope is mediated by interleukin-10 producing CD4⁺ T cellsIn: Frontiers in Immunology , Jg. 13 2022, 934399DOI, Online Volltext (Open Access)
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Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expressionIn: Nature Communications , Jg. 13 2022, Nr. 1, 156DOI (Open Access)
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SIRT1‐mediated deacetylation of FOXO3a transcription factor supports pro‐angiogenic activity of interferon‐deficient tumor‐associated neutrophilsIn: International Journal of Cancer , Jg. 150 2022, Nr. 7, S. 1198 – 1211DOI (Open Access)
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Single MHC-I Expression Promotes Virus-Induced Liver ImmunopathologyIn: Hepatology Communications , Jg. 6 2022, Nr. 7, S. 1620 – 1633DOI (Open Access)
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The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesisIn: eLife , Jg. 11 2022, e77975DOI, Online Volltext (Open Access)
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CD107a⁺ (LAMP-1) Cytotoxic CD8⁺ T-Cells in Lupus Nephritis PatientsIn: Frontiers in Medicine , Jg. 8 2021, 556776DOI, Online Volltext (Open Access)
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Characterization of the scavenger cell proteome in mouse and rat liverIn: Biological Chemistry , Jg. 402 2021, Nr. 9, S. 1073 – 1085DOI (Open Access)
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Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2In: Viruses , Jg. 13 2021, Nr. 4, 610DOI (Open Access)
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Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic CellsIn: Frontiers in Immunology , Jg. 11 2021, 607889DOI, Online Volltext (Open Access)
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Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to ImmunotherapiesIn: Cancer Research , Jg. 81 2021, Nr. 21, S. 5540 – 5554DOI (Open Access)
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Replication of influenza a virus in secondary lymphatic tissue contributes to innate immune activationIn: Pathogens , Jg. 10 2021, Nr. 5, 622DOI, Online Volltext (Open Access)
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Slow viral propagation during initial phase of infection leads to viral persistence in miceIn: Communications Biology , Jg. 4 2021, Nr. 1, 508DOI (Open Access)
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The role of ADAM17 during liver damageIn: Biological Chemistry , Jg. 402 2021, Nr. 9, S. 1115 – 1128DOI (Open Access)
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Virotherapy in Germany : recent activities in virus engineering, preclinical development, and clinical studiesIn: Viruses , Jg. 13 2021, Nr. 8, 1420DOI (Open Access)
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A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus controlIn: Journal of Hepatology , Jg. 72 2020, Nr. 5, S. 960 – 975DOI (Open Access)
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Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe diseaseIn: Nature Communications , Jg. 11 2020, Nr. 1, S. 1338DOI, Online Volltext (Open Access)
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Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma RegressionIn: Frontiers in Immunology , Jg. 11 2020, S. 1849DOI, Online Volltext (Open Access)
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CD47 as a Potential Target to Therapy for Infectious DiseasesIn: Antibodies , Jg. 9 2020, Nr. 3, S. 44DOI (Open Access)
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CEACAM1 regulates CD8⁺ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitisIn: Gut Microbes , Jg. 11 2020, Nr. 6, S. 1790 – 1805DOI (Open Access)
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens , Jg. 16 2020, Nr. 3, e1008340DOI (Open Access)
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Dead Cells Induce Innate Anergy via Mertk after Acute Viral InfectionIn: Cell Reports , Jg. 30 2020, Nr. 11, S. 3671 – 3681.e5DOI (Open Access)
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Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injuryIn: Gut , Jg. 69 2020, Nr. 1, S. 133 – 145DOI (Open Access)
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Glucose transport in lymphocytesIn: Pflügers Archiv: European Journal of Physiology , Jg. 472 2020, Nr. 9, S. 1401 – 1406
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Immunotherapeutic blockade of CD47 inhibitory signaling enhances innate and adaptive immune responses to viral infectionIn: Cell Reports , Jg. 31 2020, Nr. 2, S. 107494DOI (Open Access)
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Map3k14 as a regulator of innate and adaptive immune response during acute viral infectionIn: Pathogens , Jg. 9 2020, Nr. 2, S. 96DOI, Online Volltext (Open Access)
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NK Cells Regulate CD8⁺ T Cell Mediated AutoimmunityIn: Frontiers in Cellular and Infection Microbiology , Jg. 10 2020, 36DOI (Open Access)
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Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial CellsIn: Cell Reports Medicine , Jg. 1 2020, Nr. 8, 100142DOI (Open Access)
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Publisher Correction: Tumor-necrosis factor impairs CD4⁺ T cell–mediated immunological control in chronic viral infectionIn: Nature Immunology , Jg. 21 2020, Nr. 9, S. 1135DOI (Open Access)
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Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implicationsIn: Journal of Experimental & Clinical Cancer Research , Jg. 39 2020, 38DOI (Open Access)
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Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological ProcessesIn: Cells , Jg. 9 2020, Nr. 4, 1003DOI (Open Access)
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Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapyIn: The Journal of Clinical Investigation (JCI) , Jg. 130 2020, Nr. 8, S. 4266 – 4281DOI (Open Access)
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The diverse functions of the ubiquitous fcγ receptors and their unique constituent, fcrγ subunitIn: Pathogens , Jg. 9 2020, Nr. 2, 140DOI, Online Volltext (Open Access)
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Upregulation of CD47 is a host checkpoint response to pathogen recognitionIn: mBio , Jg. 11 2020, Nr. 3, S. e01293 – 20DOI (Open Access)
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Usp18 expression in CD169⁺ macrophages is important for strong immune response after vaccination with VSV-EBOVIn: Vaccines , Jg. 8 2020, Nr. 1, S. 142DOI, Online Volltext (Open Access)
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Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in HumansIn: The Journal of Infectious Diseases (JID) , Jg. 219 2019, Nr. 4, S. 556 – 561DOI (Open Access)
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Diverse immunomodulatory effects of individual IFNα subtypes on virus-specific CD8⁺ T cell responsesIn: Frontiers in Immunology , Jg. 10 2019, 2255DOI, Online Volltext (Open Access)
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Mechanisms of lymphatic system-specific viral replication and its potential role in autoimmune diseaseIn: Clinical and Experimental Immunology , Jg. 195 2019, Nr. 1, S. 64 – 73DOI (Open Access)
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NK cell-intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infectionIn: PLoS Pathogens , Jg. 15 2019, Nr. 6, S. e1007797DOI (Open Access)
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Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cellsIn: JCI Insight , Jg. 4 2019, Nr. 17, e129856DOI (Open Access)
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Reply [Letter to the Editor: Characterization of CD169+ Macrophages in Liver Regeneration: Tissue Distribution and Fate?]In: Hepatology , Jg. 70 2019, Nr. 3, S. 1074 – 1075DOI (Open Access)
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Stand by me(mory) : Chronic infection diminishes memory pool via IL-6/STAT1In: Journal of Experimental Medicine (JEM) , Jg. 216 2019, Nr. 3, S. 474 – 475DOI (Open Access)
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Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritisIn: BMC Nephrology , Jg. 20 2019, 430DOI, Online Volltext (Open Access)
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TLR7 Controls VSV Replication in CD169+ SCS Macrophages and Associated Viral NeuroinvasionIn: Frontiers in Immunology , Jg. 10 2019, S. 466DOI (Open Access)
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Tamoxifen protects from vesicular stomatitis virus infectionIn: Pharmaceuticals , Jg. 12 2019, Nr. 4, 142DOI, Online Volltext (Open Access)
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The uric acid crystal receptor Clec12A potentiates type I interferon responsesIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 116 2019, Nr. 37, S. 18544 – 18549DOI (Open Access)
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iRhom2 inhibits bile duct obstruction-induced liver fibrosisIn: Science Signaling , Jg. 12 2019, Nr. 605, eaax1194
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B Cell-Mediated Maintenance of Cluster of Differentiation 169–Positive Cells Is Critical for Liver RegenerationIn: Hepatology , Jg. 68 2018, Nr. 6, S. 2348 – 2361DOI (Open Access)
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CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infectionIn: Nature Communications , Jg. 9 2018, 2561DOI (Open Access)
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Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in miceIn: Hepatology , Jg. 68 2018, Nr. 1, S. 200 – 214
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Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection.In: Scientific Reports , Jg. 8 2018, Nr. 1, S. 12179DOI (Open Access)
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Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-PrimingIn: Cell Reports , Jg. 22 2018, Nr. 6, S. 1484 – 1495DOI (Open Access)
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Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral InfectionIn: Frontiers in Immunology , Jg. 9 2018, 614DOI (Open Access)
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Sphingolipids in early viral replication and innate immune activationIn: Biological Chemistry , Jg. 399 2018, Nr. 10, S. 1115 – 1123
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The probacterial effect of type I interferon signaling requires its own negative regulator USP18In: Science Immunology , Jg. 3 2018, Nr. 27, S. eaau2125DOI (Open Access)
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Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus InfectionIn: Journal of Virology , Jg. 92 2018, Nr. 3, S. e01637 – 17DOI (Open Access)
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USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1In: Journal of Virology , Jg. 92 2018, Nr. 20, e00592DOI (Open Access)
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Critical role for very-long chain sphingolipids in invariant natural killer T cell development and homeostasisIn: Frontiers in Immunology , Jg. 8 2017, S. 1386DOI (Open Access)
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Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus InfectionIn: Cellular Physiology and Biochemistry , Jg. 41 2017, Nr. 1, S. 323 – 338DOI (Open Access)
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Glycogen synthase kinase-3 modulates Cbl-b and constrains T cell activationIn: The Journal of Immunology (JI) , Jg. 199 2017, Nr. 12, S. 4056 – 4065
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IRF9 prevents CD8+ T cell exhaustion in an extrinsic manner during acute lymphocytic choriomeningitis virus infectionIn: Journal of Virology , Jg. 91 2017, Nr. 22, S. e01219 – 17DOI (Open Access)
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Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral InfectionIn: Cell Reports , Jg. 21 2017, Nr. 9, S. 2528 – 2540DOI (Open Access)
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MALT1 is an intrinsic regulator of regulatory T cellsIn: Cell Death and Differentiation , Jg. 24 2017, Nr. 7, S. 1214 – 1223DOI (Open Access)
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Presentation of autoantigen in peripheral lymph nodes is sufficient for priming autoreactive CD8+ T cellsIn: Frontiers in Immunology , Jg. 8 2017, S. 113DOI (Open Access)
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SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in MiceIn: Cellular Physiology and Biochemistry , Jg. 42 2017, Nr. 4, S. 1358 – 1365DOI (Open Access)
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Spatiotemporally restricted arenavirus replication induces immune surveillance and type i interferon-dependent tumour regressionIn: Nature Communications , Jg. 8 2017, S. 14447DOI (Open Access)
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TNFα induced up-regulation of Na+,K+,2Cl- cotransporter NKCC1 in hepatic ammonia clearance and cerebral ammonia toxicity.In: Scientific Reports , Jg. 7 2017, S. 7938DOI (Open Access)
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Virotherapy research in Germany : from engineering to translationIn: Human Gene Therapy , Jg. 28 2017, Nr. 10, S. 800 – 819
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Alkaline Cytosolic pH and High Sodium Hydrogen Exchanger 1 (NHE1) Activity in Th9 CellsIn: The Journal of Biological Chemistry (JBC) , Jg. 291 2016, Nr. 45, S. 23662 – 23671DOI (Open Access)
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Bile Acid-Induced Suicidal Erythrocyte DeathIn: Cellular Physiology and Biochemistry , Jg. 38 2016, Nr. 4, S. 1500 – 1509DOI (Open Access)
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CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infectionIn: Cell Death and Disease , Jg. 7 2016, Nr. 11, e2446DOI (Open Access)
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Expression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T LymphocytesIn: Cellular Physiology and Biochemistry , Jg. 39 2016, Nr. 3, S. 1209 – 1228DOI (Open Access)
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High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine ModelIn: Cellular Physiology and Biochemistry , Jg. 38 2016, Nr. 4, S. 1343 – 1353DOI (Open Access)
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IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sitesIn: Mucosal Immunology , Jg. 9 2016, Nr. 5, S. 1263 – 1277DOI (Open Access)
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Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responsesIn: European Journal of Immunology , Jg. 46 2016, Nr. 2, S. 372 – 380DOI (Open Access)
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Induction of the type I interferon response in neurological forms of Gaucher diseaseIn: Journal of Neuroinflammation , Jg. 13 2016, 104DOI (Open Access)
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Multiple functions of USP18In: Cell Death and Disease , Jg. 7 2016, Nr. 11, e2444DOI (Open Access)
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RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon ProductionIn: Cellular Physiology and Biochemistry , Jg. 39 2016, Nr. 4, S. 1271 – 1280DOI (Open Access)
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Storage of Erythrocytes Induces Suicidal Erythrocyte DeathIn: Cellular Physiology and Biochemistry , Jg. 39 2016, Nr. 2, S. 668 – 676DOI (Open Access)
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Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infectionIn: Nature Immunology , Jg. 17 2016, Nr. 5, S. 593 – 603
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Two separate mechanisms of enforced viral replication balance innate and adaptive immune activationIn: Journal of Autoimmunity , Jg. 67 2016, S. 82 – 89
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Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8 + T-cell priming and viral controlIn: Scientific Reports , Jg. 6 2016, 19191DOI (Open Access)
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Balancing viral replication in spleen and liver determines the outcome of systemic virus infectionIn: Zeitschrift für Gastroenterologie , Jg. 53 2015, Nr. 12, S. 1432 – 1435
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CEACAM1 induces B-cell survival and is essential for protective antiviral antibody productionIn: Nature Communications , Jg. 6 2015, 6217DOI (Open Access)
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Conjugated Bilirubin Triggers Anemia by Inducing Erythrocyte DeathIn: Hepatology , Jg. 61 2015, Nr. 1, S. 275 – 284DOI (Open Access)
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Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell KillingIn: PLoS Pathogens , Jg. 11 2015, Nr. 12, e1005364DOI (Open Access)
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Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral InfectionIn: Journal of Virology , Jg. 89 2015, Nr. 9, S. 4748 – 4759DOI (Open Access)
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Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17In: Science Signaling , Jg. 8 2015, Nr. 401, S. ra109
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Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell deathIn: OncoTarget , Jg. 6 2015, Nr. 29, S. 26909 – 26921DOI (Open Access)
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Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetaseIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 112 2015, Nr. 17, S. 5521 – 5526DOI (Open Access)
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IFN-γ licenses CD11b+ cells to induce progression of systemic lupus erythematosusIn: Journal of Autoimmunity , Jg. 62 2015, S. 11 – 21
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Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcRIn: The Journal of Immunology (JI) , Jg. 194 2015, Nr. 9, S. 4055 – 4057
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PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell KillingIn: PLoS Pathogens , Jg. 11 2015, Nr. 10, e1005224DOI (Open Access)
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T-cell STAT3 is required for the maintenance of humoral immunity to LCMVIn: European Journal of Immunology , Jg. 45 2015, Nr. 2, S. 418 – 427DOI (Open Access)
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TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infectionIn: Scientific Reports , Jg. 5 2015, 10501DOI (Open Access)
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Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infectionIn: Cell Death and Differentiation , Jg. 22 2015, Nr. 1, S. 164 – 173
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USP18 sensitivity of peptide transporters PEPT1 and PEPT2In: PLoS ONE , Jg. 10 2015, Nr. 6, e0129365DOI (Open Access)
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Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry , Jg. 36 2015, Nr. 6, S. 2379 – 2392DOI (Open Access)
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Activated CD8+ T Cells Induce Expansion of Vβ5+ Regulatory T Cells via TNFR2 SignalingIn: The Journal of Immunology (JI) , Jg. 193 2014, Nr. 6, S. 2952 – 2960DOI (Open Access)
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Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunityIn: Cell Death and Disease , Jg. 5 2014, Nr. 12, 1568DOI (Open Access)
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IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMVIn: Cell Death and Differentiation , Jg. 21 2014, Nr. 7, S. 1050 – 1060DOI (Open Access)
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Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loopIn: Cancer Research , Jg. 74 2014, Nr. 17, S. 4772 – 4782
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Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cellsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 111 2014, Nr. 3, S. 1060 – 1065
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Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicityIn: Immunity , Jg. 40 2014, Nr. 6, S. 949 – 960DOI (Open Access)
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Involvement of Toso in activation of monocytes, macrophages, and granulocytesIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 110 2013, Nr. 7, S. 2593 – 2598
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Natural killer cells regulate diverse T cell responsesIn: Trends in Immunology , Jg. 34 2013, Nr. 7, S. 342 – 349
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Reactive oxygen species delay control of lymphocytic choriomeningitis virusIn: Cell Death and Differentiation , Jg. 20 2013, Nr. 4, S. 649 – 658
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Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiencyIn: The Journal of Allergy and Clinical Immunology , Jg. 131 2013, Nr. 3, S. 815 – 824.e2
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Reply to Honjo et al.: Functional relevant expression of Toso on granulocytesIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 110 2013, Nr. 28, S. E2542 – E2543
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Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetesIn: PLoS Pathogens , Jg. 9 2013, Nr. 10DOI (Open Access)
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Antiapoptotic function of Toso (Faim3) in death receptor signalingIn: Blood , Jg. 119 2012, Nr. 7, S. 1790 – 1791
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B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in miceIn: Blood , Jg. 119 2012, Nr. 12, S. 2819 – 2828
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Effective T-cell recall responses require the taurine transporter TautIn: European Journal of Immunology , Jg. 42 2012, Nr. 4, S. 831 – 841
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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virusIn: Nature Immunology , Jg. 13 2012, Nr. 1, S. 51 – 57
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Enforced virus replication' as an immunological mechanism for adaptive immune activationIn: Immunology , Jg. 137 2012, Nr. Suppl. 1, S. 633 – 633
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Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral InfectionIn: PLoS Pathogens , Jg. 8 2012, Nr. 8, S. e1002868DOI, Online Volltext (Open Access)
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NK cells promote chronic viral infectionIn: Immunology , Jg. 137 2012, Nr. Suppl. 1, S. 129 – 129
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Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8 ⁺ T-cell immunityIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 109 2012, Nr. 4, S. 1210 – 1215DOI (Open Access)
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Reduced type I interferon production by dendritic cells and weakened antiviral immunity in Wiskott-Aldrich-Syndrome protein defiencyIn: Journal of Clinical Immunology , Jg. 32 2012, Nr. Suppl. 1, S. 46
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The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activationIn: The Journal of Immunology (JI) , Jg. 189 2012, Nr. 5, S. 2138 – 2150
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Tunicamycin inhibits diabetesIn: Cellular Physiology and Biochemistry , Jg. 29 2012, Nr. 3-4, S. 595 – 602
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iRhom2 regulates innate immunity via TACE/ADAM17In: Immunology , Jg. 137 2012, Nr. Suppl. 1, S. 147
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iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSIn: Science , Jg. 335 2012, Nr. 6065, S. 229 – 232
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Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3 : MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory efIn: The Journal of Biological Chemistry (JBC) , Jg. 286 2011, Nr. 27, S. 24113 – 24124
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Erythropoietin Requires Endothelial Nitric Oxide Synthase to Counteract TNF-α-Induced Microcirculatory Dysfunction in Murine Striated MuscleIn: Shock , Jg. 35 2011, Nr. 3, S. 315 – 321
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IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathologyIn: Cell , Jg. 144 2011, Nr. 4, S. 601 – 613DOI (Open Access)
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Interferon alpha subtype 11 selectively activates NK cells to enable control of retroviral infectionIn: Cytokine , Jg. 56 2011, Nr. 1, S. 45 – 46
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Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitinationIn: Blood , Jg. 118 2011, Nr. 3, S. 598 – 608
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Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced diseaseIn: The Journal of Immunology (JI) , Jg. 185 2010, Nr. 10, S. 6179 – 6189DOI (Open Access)
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Immune Training Enhances Anti-Viral Responses and Improves Outcomes in Pax5-/+ Mice Susceptible to Chronic InfectionIn: Blood , Jg. 144 2025, Nr. Suppl. 1, S. 1160 – 1161DOI (Open Access)
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Ceacam1 controls IL-2-dependent regulatory T cell induction in immune-mediated hepatitisIn: Journal of Hepatology , Jg. 68 2018, Nr. Suppl. 1, S. 448
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Increased infection rates in HHT patients : results of an online survey
12th International HHT Scientific Conference ; June 8–11, 2017, Dubrovnik, Croatia,In: Angiogenesis , Jg. 21 2018, Nr. 1, S. 125 – 125 -
Enforced viral replication, a mechanism for immune activation.In: European Journal of Medical Research , Jg. 19 2014, Nr. Suppl. 1, S. S26DOI (Open Access)
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Immune functions during chronic viral infectionsIn: European Journal of Medical Research , Jg. 19 2014, Nr. Suppl. 1, S. S25DOI (Open Access)
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