Personensuche
Personensuche
Es wurde 1 Person gefunden.
ZMB, Chemische Biologie, AG Kaiser
Anschrift
Universitätsstr 2
45117 Essen
45117 Essen
Raum
S03 S02 A62
Telefon
Telefax
E-Mail
Funktionen
-
Akademische/r Rätin/Rat, Chemische Biologie
Aktuelle Veranstaltungen
Vergangene Veranstaltungen (max. 10)
-
SoSe 2025
-
WiSe 2024
-
SoSe 2024
-
WiSe 2023
-
SoSe 2023
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
An unusual glycerol-3-phosphate dehydrogenase in Sulfolobus acidocaldarius elucidates the diversity of glycerol metabolism across ArchaeaIn: Communications Biology, Jg. 8, 2025, Nr. 1, 539DOI (Open Access)
-
Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiologyIn: Science, Jg. 388, 2025, Nr. 6744, S. 297 – 303
-
Conformational plasticity of a BiP-GRP94 chaperone complexIn: Nature Structural & Molecular Biology, Jg. 32, 2025, Nr. 10, S. 1947 – 1958DOI (Open Access)
-
Extracellular vesicles of patients with acute-on-chronic liver failure induce mitochondrial dysfunction in T cellsIn: Frontiers in Immunology, Jg. 16, 2025, 1656692DOI (Open Access)
-
Intraoperative Biologization of β-TCP and PCL-TCP by Autologous ProteinsIn: Journal of Functional Biomaterials, Jg. 16, 2025, Nr. 9, 340DOI, Online Volltext (Open Access)
-
Lack of AtMC1 catalytic activity triggers autoimmunity dependent on NLR stabilityIn: EMBO Reports, Jg. 26, 2025, Nr. 9, S. 2378 – 2412DOI (Open Access)
-
Small Molecule-Induced Alterations of Protein Polyubiquitination Revealed by Mass-Spectrometric Ubiquitome AnalysisIn: Angewandte Chemie International Edition, Jg. 64, 2025, Nr. 32, e202508916DOI (Open Access)
-
Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitorsIn: Nature Communications, Jg. 16, 2025, Nr. 1, 3208DOI (Open Access)
-
The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain AllosteryIn: Proteins: Structure, Function and Genetics, Jg. 93, 2025, Nr. 9, S. 1481 – 1497DOI (Open Access)
-
The CAPE1 peptide confers resistance against bacterial wilt in tomatoIn: Journal of Experimental Botany (JEB), Jg. 76, 2025, Nr. 15, S. 4340 – 4358DOI (Open Access)
-
The serine protease HTRA1 targets tau fibrils and provides a proteolytic barrier against pathogenic protein conformationsIn: The Journal of Biological Chemistry (JBC), Jg. 301, 2025, Nr. 10, 110729DOI (Open Access)
-
Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant–pathogen interfaceIn: New Phytologist, Jg. 241, 2024, Nr. 1, S. 394 – 408DOI (Open Access)
-
Characterization of 2-phenanthroate:CoA ligase from the sulfate-reducing, phenanthrene-degrading enrichment culture TRIPIn: Applied and Environmental Microbiology, Jg. 90, 2024, Nr. 10, e0129624DOI (Open Access)
-
Differences in the Synovial Fluid Proteome of Septic and Aseptic Implant FailureIn: Antibiotics, Jg. 13, 2024, Nr. 4, 346DOI, Online Volltext (Open Access)
-
Discovery of active mouse, plant and fungal cytochrome P450s in endogenous proteomes and upon expression in plantaIn: Scientific Reports, Jg. 14, 2024, Nr. 1, 10091DOI (Open Access)
-
Environmental activity-based protein profiling for function-driven enzyme discovery from natural communitiesIn: Environmental Microbiomes, Jg. 19, 2024, Nr. 1, 36DOI, Online Volltext (Open Access)
-
Extracellular plant subtilases dampen cold-shock peptide elicitor levelsIn: Nature Plants, Jg. 10, 2024, Nr. 11, S. 1749 – 1760DOI (Open Access)
-
Factors governing attachment of Rhizobium leguminosarum to legume roots at acid, neutral, and alkaline pHsIn: mSystems, Jg. 9, 2024, Nr. 9, e0042224DOI (Open Access)
-
Glutathione Transferase Photoaffinity Labeling Displays GST Induction by Safeners and Pathogen InfectionIn: Plant and Cell Physiology, Jg. 65, 2024, Nr. 1, S. 128 – 141DOI (Open Access)
-
High resolution analysis of proteolytic substrate processingIn: The Journal of Biological Chemistry (JBC), Jg. 300, 2024, Nr. 11, 107812DOI (Open Access)
-
Induced degradation of SNAP-fusion proteinsIn: RSC Chemical Biology, Jg. 5, 2024, Nr. 12, S. 1232 – 1247DOI (Open Access)
-
Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptorIn: Current Biology, Jg. 34, 2024, Nr. 11, S. 2279 – 2293.e6DOI (Open Access)
-
Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplastIn: Nature Communications, Jg. 15, 2024, Nr. 1, 10431DOI (Open Access)
-
The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113In: Cell Chemical Biology, Jg. 31, 2024, Nr. 10, S. 1755 – 1771.e73DOI (Open Access)
-
The proteome of Nicotiana benthamiana is shaped by extensive protein processingIn: New Phytologist, Jg. 243, 2024, Nr. 3, S. 1034 – 1049DOI (Open Access)
-
TopBP1 utilises a bipartite GINS binding mode to support genome replicationIn: Nature Communications, Jg. 15, 2024, Nr. 1, 1797DOI, Online Volltext (Open Access)
-
Chemoproteomics Reveals the Pan-HER Kinase Inhibitor Neratinib To Target an Arabidopsis Epoxide Hydrolase Related to Phytohormone SignalingIn: ACS Chemical Biology, Jg. 18, 2023, Nr. 5, S. 1076 – 1088
-
Clp-targeting BacPROTACs impair mycobacterial proteostasis and survivalIn: Cell, Jg. 186, 2023, Nr. 10, S. 2176 – 2192.e22DOI (Open Access)
-
IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilizationIn: Cell Chemical Biology, Jg. 30, 2023, Nr. 6, S. 573 – 590.e6DOI, Online Volltext (Open Access)
-
Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrateIn: Nature Communications, Jg. 14, 2023, Nr. 1, 5942DOI (Open Access)
-
Taspase1 facilitates Topoisomerase IIβ-mediated DNA double-strand breaks driving estrogen-induced transcriptionIn: Cells, Jg. 2023, 2023, Nr. 12, 363DOI, Online Volltext (Open Access)
-
The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications, Jg. 14, 2023, Nr. 1, 3258DOI, Online Volltext (Open Access)
-
The root pathogen Aphanomyces euteiches secretes modular proteases in pea apoplast during host infectionIn: Frontiers in Plant Science (FPLS), Jg. 14, 2023, 1140101DOI (Open Access)
-
Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1EIn: Frontiers in Microbiology, Jg. 12, 2022, 734039DOI, Online Volltext (Open Access)
-
Erratum: Author Correction: Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling (Communications biology (2022) 5 1 (1254))In: Communications Biology, Jg. 5, 2022, Nr. 1, S. 1319DOI (Open Access)
-
Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profilingIn: Communications Biology, Jg. 5, 2022, Nr. 1, 1254DOI, Online Volltext (Open Access)
-
Persister state-directed transitioning and vulnerability in melanoma
32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,In: Nature Communications, Jg. 13, 2022, Nr. 1, S. 35 – 36DOI, Online Volltext (Open Access) -
Article leaf apoplast of field-grown potato analyzed by quantitative proteomics and activity-based protein profilingIn: International Journal of Molecular Sciences (IJMS), Jg. 22, 2021, Nr. 21, 12033DOI (Open Access)
-
Correction to : Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteriaIn: Applied Microbiology and Biotechnology, Jg. 105, 2021, Nr. 14-15, S. 6119 – 6119DOI (Open Access)
-
Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports, Jg. 37, 2021, Nr. 8, 110056DOI, Online Volltext (Open Access)
-
Targeted substrate loop insertion by VCP/p97 during PP1 complex disassemblyIn: Nature Structural & Molecular Biology, Jg. 28, 2021, Nr. 12, S. 964 – 971
-
The chemical compound ‘Heatin’ stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilasesIn: The Plant Journal, Jg. 106, 2021, Nr. 6, S. 1523 – 1540DOI (Open Access)
-
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances, Jg. 10, 2020, Nr. 48, S. 28711 – 28719DOI (Open Access)
-
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances, Jg. 10, 2020, Nr. 48, S. 28711 – 28719DOI (Open Access)
-
Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture methodIn: Biomolecules, Jg. 10, 2020, Nr. 4, 661DOI (Open Access)
-
Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteriaIn: Applied Microbiology and Biotechnology, Jg. 104, 2020, Nr. 13, S. 5985 – 5998DOI (Open Access)
-
Protein Phosphatase-1 Complex Disassembly by p97 is Initiated through Multivalent Recognition of Catalytic and Regulatory Subunits by the p97 SEP-domain AdaptersIn: Journal of Molecular Biology (JMB), Jg. 432, 2020, Nr. 23, S. 6061 – 6074
-
Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry, Jg. 401, 2020, Nr. 8, S. 955 – 968DOI (Open Access)
-
Using proteomics for an insight into the performance of activated sludge in a lab-scale WWTPIn: International Biodeterioration & Biodegradation, Jg. 149, 2020, S. 104934
-
Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product FamilyIn: Chemistry - A European Journal, Jg. 26, 2020, Nr. 39, S. 8524 – 8531DOI (Open Access)
-
A homology-guided, genome-based proteome for improved proteomics in the alloploid Nicotiana benthamianaIn: BMC Genomics, Jg. 20, 2019, Nr. 1, S. 722DOI (Open Access)
-
Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor S/CYS8 in Nicotiana benthamianaIn: Plant Biotechnology Journal, Jg. 17, 2019, Nr. 8, S. 1670 – 1678DOI (Open Access)
-
Cathepsin L regulates metabolic networks controlling rapid cell growth and proliferationIn: Molecular and Cellular Proteomics (MCP), Jg. 18, 2019, Nr. 7, S. 1330 – 1344DOI (Open Access)
-
Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam CellsIn: Cellular Physiology and Biochemistry, Jg. 53, 2019, Nr. 3, S. 550 – 572DOI (Open Access)
-
Dynamic hydrolase labelling as a marker for seed quality in Arabidopsis seedsIn: Biochemical Journal, Jg. 476, 2019, Nr. 5, S. 843 – 857DOI (Open Access)
-
Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptidesIn: Science, Jg. 364, 2019, Nr. 6436, eaav0748DOI, Online Volltext (Open Access)
-
Metabolic reconstruction of the genome of candidate Desulfatiglans TRIP_1 and identification of key candidate enzymes for anaerobic phenanthrene degradationIn: Environmental Microbiology, Jg. 21, 2019, Nr. 4, S. 1267 – 1286DOI (Open Access)
-
Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathwayIn: Scientific Reports, Jg. 9, 2019, Nr. 1, S. 11196DOI (Open Access)
-
Proteases underground : Analysis of the maize root apoplast identifies organ specific papain-like cysteine protease activityIn: Frontiers in Plant Science (FPLS), Jg. 10, 2019DOI (Open Access)
-
Triazine probes target ascorbate peroxidases in plantsIn: Plant Physiology, Jg. 180, 2019, Nr. 4, S. 1848 – 1859DOI (Open Access)
-
A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPasesIn: Angewandte Chemie International Edition, Jg. 57, 2018, Nr. 6, S. 1576 – 1580
-
An apoplastic peptide activates salicylic acid signalling in maizeIn: Nature Plants, Jg. 4, 2018, Nr. 3, S. 172 – 180DOI, Online Volltext (Open Access)
-
Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitatsIn: ISME Journal, Jg. 12, 2018, Nr. 8, S. 2039 – 2050DOI (Open Access)
-
HTRA1-Dependent Cell Cycle ProteomicsIn: Journal of Proteome Research, Jg. 17, 2018, Nr. 8, S. 2679 – 2694
-
Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent ProbesIn: ACS Chemical Biology, Jg. 13, 2018, Nr. 5, S. 1307 – 1312
-
Identification of the Natural Product RotihibinA as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional ProfilingIn: Chemistry - A European Journal, Jg. 24, 2018, Nr. 48, S. 12500 – 12504
-
Low Protease Content in Medicago truncatula Cell Cultures Facilitates Recombinant Protein ProductionIn: Biotechnology Journal, Jg. 13, 2018, Nr. 7, 1800050
-
Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in PlantsIn: Plant Physiology, Jg. 177, 2018, Nr. 1, S. 24 – 37DOI, Online Volltext (Open Access)
-
Protease Activities Triggered by Ralstonia solanacearum Infection in Susceptible and Tolerant Tomato LinesIn: Molecular and Cellular Proteomics (MCP), Jg. 17, 2018, Nr. 6, S. 1112 – 1125DOI, Online Volltext (Open Access)
-
The transcriptome, extracellular proteome and active secretome of agroinfiltrated Nicotiana benthamiana uncover a large, diverse protease repertoireIn: Plant Biotechnology Journal, Jg. 16, 2018, Nr. 5, S. 1068 – 1084DOI (Open Access)
-
Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamianaIn: Plant Biotechnology Journal, Jg. 16, 2018, Nr. 10, S. 1797 – 1810DOI (Open Access)
-
Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme FormationIn: Molecular Cell, Jg. 72, 2018, Nr. 4, S. 766 – 777DOI (Open Access)
-
Utilities for Mass Spectrometry Analysis of Proteins (UMSAP) : Fast post-processing of mass spectrometry dataIn: Rapid Communications in Mass Spectrometry, Jg. 32, 2018, Nr. 19, S. 1659 – 1667
-
Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic ArchaeaIn: Nature Communications, Jg. 8, 2017, S. 15352DOI (Open Access)
-
Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expressionIn: Antioxidants and Redox Signaling, Jg. 26, 2017, Nr. 11, S. 563 – 582DOI (Open Access)
-
Proteasome activity profiling uncovers alteration of catalytic β2 and β5 subunits of the stress-induced proteasome during salinity stress in tomato rootsIn: Frontiers in Plant Science (FPLS), Jg. 8, 2017, 107DOI (Open Access)
-
Quantitative proteomics reveals ecophysiological effects of light and silver stress on the mixotrophic protist Poterioochromonas malhamensisIn: PLoS ONE, Jg. 12, 2017, Nr. 1, S. e0168183DOI, Online Volltext (Open Access)
-
Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infectionsIn: The Plant Journal, Jg. 90, 2017, Nr. 2, S. 418 – 430
-
The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian ClockIn: ACS Chemical Biology, Jg. 12, 2017, Nr. 6, S. 1466 – 1471DOI (Open Access)
-
A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosisIn: Chemical Science, Jg. 7, 2016, S. 1322 – 1337DOI (Open Access)
-
Capture of endogenously biotinylated proteins from Pseudomonas aeruginosa displays unexpected downregulation of LiuD upon iron nutritionIn: Bioorganic and Medicinal Chemistry, Jg. 24, 2016, Nr. 15, S. 3330 – 3335
-
Screen of Non-annotated Small Secreted Proteins of Pseudomonas syringae Reveals a Virulence Factor That Inhibits Tomato Immune ProteasesIn: PLoS Pathogens, Jg. 12, 2016, Nr. 9, S. 1005874DOI (Open Access)
-
VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break RepairIn: Molecular Cell, Jg. 64, 2016, Nr. 1, S. 189 – 198DOI (Open Access)
-
Chemical proteomics versus LeishmaniasisIn: Chemistry and Biology, Jg. 22, 2015, Nr. 3, S. 309 – 310DOI (Open Access)
-
Chemoproteomic Evaluation of the Polyacetylene Callyspongynic AcidIn: Chemistry - A European Journal, Jg. 21, 2015, Nr. 30, S. 10721 – 10728DOI (Open Access)
-
Determinants of amyloid fibril degradation by the PDZ protease HTRA1In: Nature Chemical Biology, Jg. 11, 2015, Nr. 11, S. 862 – 869DOI, Online Volltext (Open Access)
-
Functional divergence of two secreted immune proteases of tomatoIn: Current Biology, Jg. 25, 2015, Nr. 17, S. 2300 – 2306DOI (Open Access)
-
Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem, Jg. 15, 2014, Nr. 15, S. 2233 – 2237
-
A substrate-inspired probe monitors translocation, activation, and subcellular targeting of bacterial type III effector protease AvrPphBIn: Chemistry and Biology, Jg. 20, 2013, Nr. 2, S. 168 – 176
-
Profiling protein kinases and other ATP binding proteins in arabidopsis using acyl-ATP probesIn: Molecular and Cellular Proteomics (MCP), Jg. 12, 2013, Nr. 9, S. 2481 – 2496
-
Pseudomonas syringae pv. syringae Uses Proteasome Inhibitor Syringolin A to Colonize from Wound Infection SitesIn: PLoS Pathogens, Jg. 9, 2013, Nr. 3, S. e1003281DOI (Open Access)
-
Streamlining chemical probe discovery : libraries of "fully functionalized" small molecules for phenotypic screeningIn: Angewandte Chemie International Edition, Jg. 52, 2013, Nr. 5, S. 1368 – 1370
-
A maize cystatin suppresses host immunity by inhibiting apoplastic cysteine proteasesIn: The Plant Cell, Jg. 24, 2012, Nr. 3, S. 1285 – 1300
-
A para-nitrophenol phosphonate probe labels distinct serine hydrolases of ArabidopsisIn: Bioorganic and Medicinal Chemistry, Jg. 20, 2012, Nr. 2, S. 601 – 606
-
Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenasesIn: Angewandte Chemie International Edition, Jg. 51, 2012, Nr. 21, S. 5230 – 5233
-
Selective inhibition of plant serine hydrolases by agrochemicals revealed by competitive ABPPIn: Bioorganic and Medicinal Chemistry, Jg. 20, 2012, Nr. 2, S. 597 – 600DOI, Online Volltext (Open Access)
-
The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipainsIn: Chemistry and Biology, Jg. 19, 2012, Nr. 12, S. 1546 – 1555
-
Proteasome activity imaging and profiling characterizes bacterial effector Syringolin AIn: Plant Physiology, Jg. 155, 2011, Nr. 1, S. 477 – 489DOI, Online Volltext (Open Access)
-
Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using ‘click chemistry’.In: The Plant Journal, Jg. 57, 2009, Nr. 2, S. 373 – 385
-
Redirecting resistance evolution in BRAFV600 melanoma by inhibition of the peroxiredoxin-thioredoxin system2025DOI (Open Access)
-
Targeted degradation of USP7 in solid cancer cells reveals disparate effects of deubiquitinase inhibition vs. acute protein depletion2025DOI, Online Volltext (Open Access)
-
A non-autonomous protein quality control mechanism targeting tau aggregate propagation2024DOI (Open Access)
-
Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase2024DOI (Open Access)
-
Ipl1-controlled attachment maturation regulates Mps1 association with its kinetochore receptor2023DOI (Open Access)
-
Cysteine Reactivity Profiling to Unveil Redox Regulation in PhytopathogensIn: Plant Proteases and Plant Cell Death: Methods and Protocols / Klemenčič, Marina; Stael, Simon; Huesgen, Pitter F. (Hrsg.). New York; Clifton, NJ; Totowa, NJ: Springer, 2022, S. 105 – 117
-
Activity-based protein profiling with natural product-derived chemical probes in human cell lysatesIn: Activity-Based Proteomics: Methods and Protocols / Overkleeft, Herman S.; Florea, Bogdan I. (Hrsg.). New York: Springer, 2017, S. 23 – 46