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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Virologie
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WiSe 2025
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITAIn: eLife, Jg. 14, 2025, e96414DOI, Online Volltext (Open Access)
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Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furinIn: Virus Research, Jg. 350, 2024, 199485DOI (Open Access)
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Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterningIn: eLife, Jg. 13, 2024, e85560DOI (Open Access)
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UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an exampleIn: BMC Genomics, Jg. 25, 2024, Nr. 1, 647DOI, Online Volltext (Open Access)
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A simple algorithm based on initial Ct values predicts the duration to SARS-CoV-2 negativity and allows more efficient test-to-release and return-to-work schedulesIn: Diagnostic Microbiology and Infectious Disease, Jg. 106, 2023, Nr. 3, 115949DOI, Online Volltext (Open Access)
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Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cellsIn: European Journal of Immunology, Jg. 53, 2023, Nr. 2, 2249940DOI, Online Volltext (Open Access)
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Antibody responses elicited by mRNA vaccination in firefighters persist six months and correlate inversely with age and directly with BMIIn: Heliyon, Jg. 9, 2023, Nr. 1, e12746DOI, Online Volltext (Open Access)
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Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulationIn: Frontiers in Immunology, Jg. 14, 2023, 1170300DOI, Online Volltext (Open Access)
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Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirusIn: npj Vaccines, Jg. 8, 2023, Nr. 1, 8DOI, Online Volltext (Open Access)
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Persistence of KIRⁿeg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivationIn: Frontiers in Immunology, Jg. 14, 2023, 1266051DOI (Open Access)
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SARS-CoV-2 particles promote airway epithelial differentiation and ciliationIn: Frontiers in Bioengineering and Biotechnology, Jg. 11, 2023, 1268782DOI (Open Access)
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Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptorIn: The EMBO Journal, Jg. 42, 2023, Nr. 5, e112351DOI (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio, Jg. 14, 2023, Nr. 6, e02357-23DOI, Online Volltext (Open Access)
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Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infectionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 119, 2022, Nr. 8, e2111600119DOI (Open Access)
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Discrepancy between frequent occurrence of COVID-19-like symptoms and low seroconversion rates among healthcare workersIn: Journal of Medical Virology, Jg. 94, 2022, Nr. 3: Special Issue on New coronavirus (2019‐nCoV or SARS‐CoV‐2) and the outbreak of the respiratory illness (COVID‐19): Part‐XVIII, S. 951 – 957DOI (Open Access)
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Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies virus neutralizing antibodiesIn: PLoS Neglected Tropical Diseases, Jg. 16, 2022, Nr. 5, e0010425DOI, Online Volltext (Open Access)
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Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitroIn: BMC Biology (incorporating Journal of Biology), Jg. 20, 2022, Nr. 1, 264DOI, Online Volltext (Open Access)
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Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitroIn: Emerging Microbes & Infections, Jg. 11, 2022, Nr. 1, S. 483 – 497DOI, Online Volltext (Open Access)
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A rapid test recognizing mucosal SARS-CoV-2-specific antibodies distinguishes prodromal from convalescent COVID-19In: iScience, Jg. 24, 2021, Nr. 10, 103194DOI (Open Access)
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Human cytomegalovirus antagonizes activation of fcγ receptors by distinct and synergizing modes of igg manipulationIn: eLife, Jg. 10, 2021, S. e63877DOI (Open Access)
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Nedd8-activating enzyme is a druggable host dependency factor of human and mouse cytomegalovirusIn: Viruses, Jg. 13, 2021, Nr. 8, 1610DOI, Online Volltext (Open Access)
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Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral ImmunityIn: Frontiers in Immunology, Jg. 12, 2021, 722027DOI, Online Volltext (Open Access)
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Over 90% of clinical swabs used for SARS-CoV-2 diagnostics contain sufficient nucleic acid concentrationsIn: Journal of Medical Virology, Jg. 93, 2021, Nr. 5, S. 2848 – 2856DOI (Open Access)
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Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in miceIn: European Journal of Immunology, Jg. 51, 2021, Nr. 2, S. 393 – 407DOI (Open Access)
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Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCTIn: JCI Insight, Jg. 6, 2021, Nr. 12, e146973DOI (Open Access)
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The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele : MICA*008, to evade NK cell-mediated killingIn: PLoS Pathogens, Jg. 17, 2021, Nr. 5, S. e1008807DOI (Open Access)
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Turmeric root and its bioactive ingredient curcumin effectively neutralize sars-cov-2 in vitroIn: Viruses, Jg. 13, 2021, Nr. 10, 1914DOI, Online Volltext (Open Access)
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A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral CompoundsIn: Frontiers in Immunology, Jg. 11, 2020, S. 573526DOI, Online Volltext (Open Access)
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Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion modelsIn: Journal of Experimental Medicine (JEM), Jg. 217, 2020, Nr. 3, S. e20191164DOI (Open Access)
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Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral ReplicationIn: Frontiers in Cellular and Infection Microbiology, Jg. 10, 2020, 171DOI, Online Volltext (Open Access)
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Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapyIn: The Journal of Clinical Investigation (JCI), Jg. 130, 2020, Nr. 8, S. 4266 – 4281DOI, Online Volltext (Open Access)
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The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate ImmunityIn: Cell Reports, Jg. 30, 2020, Nr. 7, S. 2248 – 2260.e5DOI (Open Access)
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Ub to no good : How cytomegaloviruses exploit the ubiquitin proteasome systemIn: Virus Research, Jg. 281, 2020, S. 197938
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Cellular Cullin RING Ubiquitin Ligases : Druggable Host Dependency Factors of CytomegalovirusesIn: International Journal of Molecular Sciences (IJMS), Jg. 20, 2019, Nr. 7, S. 1636DOI, Online Volltext (Open Access)
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HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11In: PLoS Pathogens, Jg. 15, 2019, Nr. 9, S. e1008040DOI (Open Access)
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Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infectionIn: PLoS Pathogens, Jg. 15, 2019, Nr. 9, e1008043DOI (Open Access)
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Publisher Correction : m6A modification controls the innate immune response to infection by targeting type I interferonsIn: Nature Immunology, Jg. 20, 2019, Nr. 2, S. 243DOI (Open Access)
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m⁶A modification controls the innate immune response to infection by targeting type I interferonsIn: Nature Immunology, Jg. 20, 2019, S. 173 – 183
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A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded VpxIn: Frontiers in Immunology, Jg. 9, 2018, S. 2978DOI (Open Access)
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STAT2-Dependent immune responses ensure host survival despite the presence of a potent viral antagonistIn: Journal of Virology, Jg. 92, 2018, Nr. 14, S. e00296 – 18.DOI (Open Access)
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The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant RecipientsIn: Frontiers in Immunology, Jg. 9, 2018, S. 917DOI, Online Volltext (Open Access)
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The human cytomegalovirus protein UL148A downregulates the NK cell-activating ligand MICA to avoid NK cell attackIn: Journal of Virology, Jg. 92, 2018, Nr. 17, S. e00162 – 18DOI, Online Volltext (Open Access)
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Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.In: Frontiers in Immunology, Jg. 14, 2017, Nr. 8, 1139DOI (Open Access)
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Human cytomegalovirus-induced degradation of CYTIP modulates dendritic cell adhesion and migrationIn: Frontiers in Immunology, Jg. 8, 2017, 461DOI (Open Access)
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Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture systemIn: PLoS ONE, Jg. 12, 2017, Nr. 3, e0174695DOI (Open Access)
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Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in HepatocytesIn: Journal of Virology, Jg. 90, 2016, Nr. 15, S. 6686 – 6698DOI (Open Access)
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Broad and potent antiviral activity of the NAE inhibitor MLN4924In: Scientific Reports, Jg. 6, 2016, 19977DOI (Open Access)
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HCMV vCXCL1 Binds Several Chemokine Receptors and Preferentially Attracts Neutrophils over NK Cells by Interacting with CXCR2In: Cell Reports, Jg. 15, 2016, Nr. 7, S. 1542 – 1553DOI (Open Access)
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MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infectionsIn: Journal of Hepatology, Jg. 64, 2016, Nr. 2, S. 380 – 389
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Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 NexusIn: Cell Reports, Jg. 17, 2016, Nr. 6, S. 1571 – 1583DOI (Open Access)
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Attack, parry and riposte : Molecular fencing between the innate immune system and human herpesvirusesIn: Tissue Antigens, Jg. 86, 2015, Nr. 1, S. 1 – 13
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Dynamic co-evolution of host and pathogen : HCMV downregulates the prevalent allele MICA*008 to escape elimination by NK cellsIn: Cell Reports, Jg. 10, 2015, Nr. 6, S. 968 – 982DOI (Open Access)
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The canonical immediate early 3 gene product pIE611 of mouse cytomegalovirus is dispensable for viral replication but mediates transcriptional and posttranscriptional regulation of viral gene productsIn: Journal of Virology, Jg. 89, 2015, Nr. 16, S. 8590 – 8598DOI (Open Access)
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The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactionsIn: PLoS Pathogens, Jg. 11, 2015, Nr. 11, e1005288DOI (Open Access)
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"Activated" STAT proteins : a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cellsIn: The Journal of Immunology (JI), Jg. 192, 2014, Nr. 1, S. 447 – 458DOI (Open Access)
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Checks and balances between human cytomegalovirus replication and indoleamine-2,3- dioxygenaseIn: Journal of General Virology, Jg. 95, 2014, S. 659 – 670
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Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and IIIIn: PLoS Pathogens, Jg. 10, 2014, Nr. 5, e1004131DOI (Open Access)
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IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansionIn: The Journal of Clinical Investigation (JCI), Jg. 124, 2014, Nr. 12, S. 5305 – 5316
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MicroRNA Editing Facilitates Immune Elimination of HCMV Infected CellsIn: PLoS Pathogens, Jg. 10, 2014, Nr. 2, e1003963DOI (Open Access)
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Interplay between CMVs and interferon signaling : Implications for pathogenesis and therapeutic interventionIn: Future Microbiology, Jg. 7, 2012, Nr. 11, S. 1269 – 1282
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Analyses of defined human cytomegalovirus-specific antibody effector functions in people living with human immunodeficiency virus
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine. Hoboken: Wiley-Blackwell, Jg. 24, 2023, Nr. 1, S. 48 – 49 -
Cytomegalovirus infection aggravates intestinal inflammation during colitis and impairs the convalescence of the intestinal niche
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology. Hoboken: Wiley, Jg. 53, 2023, Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 354DOI (Open Access) -
Human cytomegalovirus interferes with dendritic cell adhesion and migration via the proteasomal degradation of the cytohesin-1 interacting protein
15th International Symposium on Dendritic Cells, 10–14 June 2018, Aachen, Germany,In: European Journal of Immunology. Hoboken: Wiley, Jg. 48, 2018, Nr. Suppl. 1, S. 103 – 104DOI (Open Access)