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Aktuelle Veranstaltungen
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SoSe 2025
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
Vergangene Veranstaltungen (max. 10)
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WiSe 2024
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SoSe 2024
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
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WiSe 2023
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Protein Levels of Anti-Apoptotic Mcl-1 and the Deubiquitinase USP9x Are Cooperatively Upregulated during Prostate Cancer Progression and Limit Response of Prostate Cancer Cells to RadiotherapyIn: Cancers , Jg. 15 2023, Nr. 9, 2496DOI, Online Volltext (Open Access)
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CD9- and CD81-positive extracellular vesicles provide a marker to monitor glioblastoma cell response to photon-based and proton-based radiotherapyIn: Frontiers in Oncology , Jg. 12 2022, 947439DOI, Online Volltext (Open Access)
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Correction to : Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapyIn: Cell Death and Disease , Jg. 13 2022, Nr. 4, 367DOI (Open Access)
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Activation of anti-oxidant Keap1/Nrf2 pathway modulates efficacy of dihydroartemisinin-based monotherapy and combinatory therapy with ionizing radiationIn: Free Radical Biology and Medicine , Jg. 168 2021, S. 44 – 54
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Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapyIn: Cell Death and Disease , Jg. 12 2021, Nr. 7, 694DOI, Online Volltext (Open Access)
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Loss of pro-apoptotic Bax and Bak increases resistance to dihydroartemisinin-mediated cytotoxicity in normoxia but not in hypoxia in HCT116 colorectal cancer cellsIn: Free Radical Biology and Medicine , Jg. 174 2021, S. 157 – 170
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Effects of Irradiation with Protons and Photons on the Survival of Glioblastoma Cell Lines and the Secretion of Exosomes in vitroIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 195 2019, Nr. Suppl. 1, S. 173
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Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanismsIn: Cell Death and Disease , Jg. 7 2016, Nr. 1, e2039DOI (Open Access)
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Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxiaIn: Radiation Oncology , Jg. 11 2016, Nr. 1, S. 75 – 87DOI (Open Access)
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Targeting TRPM2 channels impairs radiation-induced cell cycle arrest and fosters cell death of T cell leukemia cells in a Bcl-2-dependent mannerIn: Oxidative Medicine and Cellular Longevity 2016 , Article number 8026702DOI (Open Access)
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The Focinator - a new open-source tool for high-throughput foci evaluation of DNA damageIn: Radiation Oncology 2015, Nr. 10, S. 163 – 174DOI (Open Access)
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Dihydroartemisinin is a hypoxia-active anti-cancer drug in colorectal carcinoma cellsIn: Frontiers in Oncology , Jg. 4 2014, S. 116DOI (Open Access)
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Importance of Mcl-1 and the Mcl-1-modulating enzyme USP9x for radiosensitivity in prostate cancer cellsIn: European Journal of Cancer (EJC) , Jg. 50 2014, Nr. Suppl. 5, S. S225 – S226
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Neonatal monocytes express antiapoptotic pattern of Bcl-2 proteins and show diminished apoptosis upon infection with Escherichia coliIn: Pediatric Research , Jg. 76 2014, Nr. 2, S. 142 – 149
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Kv3.4 potassium channel-mediated electrosignaling controls cell cycle and survival of irradiated leukemia cellsIn: Pflügers Archiv: European Journal of Physiology , Jg. 465 2013, Nr. 8, S. 1209 – 1221
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Regulation of protein translation initiation in response to ionizing radiationIn: Radiation Oncology , Jg. 8 2013, S. 35DOI (Open Access)
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The deubiquitinase USP9x modulates sensitivity to radiation-induced apoptosis by stabilizing Mcl-1 levelsIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 189 2013, Nr. Suppl. 1, S. 126 – 126
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Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1In: Neoplasia: An International Journal for Oncology Research , Jg. 14 2012, Nr. 10, S. 893 – 904DOI (Open Access)
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Ionizing radiation induces cell migration of glioblastoma cells by Ca2+-dependent activation of K+ and Cl- channelsIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 188 2012, Nr. Suppl. 1, S. 133
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Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosisIn: Biochemical Pharmacology , Jg. 81 2011, Nr. 1, S. 32 – 42
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Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on Celecoxib-induced apoptosisIn: Biochemical Pharmacology , Jg. 79 2010, Nr. 1, S. 10 – 20
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The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiationIn: Radiation Oncology , Jg. 5 2010, Nr. 1, S. 108DOI, Online Volltext (Open Access)
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Dihydroartemisinin shows similar anti-neoplastic activity in hypoxia in apoptosis-proficient and apoptosis-deficient HCT116 cellsIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 191 2015, Nr. Suppl.1, S. 79 – S80
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Myeloid cell leukemia-1 and ubiquitin-specific protease 9x improve cells survival in irradiated A172 glioblastoma cellsIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 190 2014, Nr. Suppl. 1, S. 80
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Regulierung der protektiven Funktion anti-apoptotischer Proteine der Bcl-2-ProteinfamilieDuisburg, Essen 2014