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PD Dr. Thorsten R. Döppner

Klinik für Neurologie am Universitätsklinikum Essen

Anschrift
Hufelandstr. 55
45122 Essen
E-Mail
thorsten.doeppner@uk-essen.de

Funktionen

  • Facharzt/-ärztin, Klinik für Neurologie

Aktuelle Veranstaltungen

Keine aktuellen Veranstaltungen.

Vergangene Veranstaltungen (max. 10)

Keine vergangenen Veranstaltungen.

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Beker, Mustafa C.; Sertel Evren, Elif; Özbay, Elif; Balaban, Buse; Dogan, Enes; Yelkenci, Hayriye E.; Ates, Nilay; Caglayan, Ahmet B.; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Circadian clock protein Bmal1 protects against transient focal cerebral ischemia in mice by regulating master signals controlling cell survival and metabolism
    In: Experimental Neurology, Jg. 395, 2026, 115481
    DOI (Open Access)
  • Cercel, Andreea-Mihaela; Boboc, Ianis Ks; Surugiu, Roxana; Doeppner, Thorsten R.; Hermann, Dirk M.; Catalin, Bogdan; Gresita, Andrei; Popa-Wagner, Aurel
    Grafts of hydrogel-embedded electrically stimulated subventricular stem cells into the stroke cavity improves functional recovery of mice
    In: Neural Regeneration Research, Jg. 21, 2026, Nr. 2, S. 695 – 703
    DOI (Open Access)
  • Cercel, Andreea; Mihaela, Abuzan; Döppner, Thorsten R.; Hermann, Dirk M.; Martin, Liviu; Popa-Wagner, Aurel
    Ischemic stroke and comorbidities : Impact on recovery and the role of genetics and epigenetics
    In: Mechanisms of Ageing and Development, Jg. 229, 2026, 112127
    DOI (Open Access)
  • Luegering, Anneke; Frohnhofen, Helmut; Langner, Robert; Wilm, Stefan; Döppner, Thorsten R.; Hermann, Dirk M.; Windolf, Joachim; Gronewold, Janine
    Assessing medication self-management by the elderly : a comparison of subjective and objective indicators from the ABLYMED study
    In: Deutsches Ärzteblatt International, Jg. 122, 2025, Nr. 2, S. 55 – 56
    DOI (Open Access)
  • Grigore, Monica; Ruscu, Mihai Andrei; Hermann, Dirk M.; Colita, Ivan-Cezar; Doeppner, Thorsten Roland; Glavan, Daniela; Popa-Wagner, Aurel
    Biomarkers of cognitive and memory decline in psychotropic drug users
    In: Journal of Neural Transmission, Jg. 132, 2025, Nr. 1, S. 39 – 59
    DOI (Open Access)
  • Pirscoveanu, Denisa F. V.; Olaru, Denissa Greta; Hermann, Dirk M.; Doeppner, Thorsten R.; Ghinea, Flavia Semida; Popa-Wagner, Aurel
    Correction to: Immune genes involved in synaptic plasticity during early postnatal brain development contribute to post-stroke damage in the aging male rat brain
    In: Biogerontology, Jg. 26, 2025, Nr. 3, 98
    DOI (Open Access)
  • Abuzan, Mihaela; Surugiu, Roxana; Wang, Chen; Mohamud-Yusuf, Ayan; Tertel, Tobias; Catalin, Bogdan; Döppner, Thorsten R.; Giebel, Bernd; Hermann, Dirk M.; Popa-Wagner, Aurel
    Extracellular Vesicles Obtained from Hypoxic Mesenchymal Stromal Cells Induce Neurological Recovery, Anti-inflammation, and Brain Remodeling After Distal Middle Cerebral Artery Occlusion in Rats
    In: Translational Stroke Research, Jg. 16, 2025, Nr. 3, S. 817 – 830
    DOI (Open Access)
  • Hermann, Dirk M.; Wang, Chen; Mohamud Yusuf, Ayan; Herz, Josephine; Döppner, Thorsten R.; Giebel, Bernd
    Extracellular vesicles lay the ground for neuronal plasticity by restoring mitochondrial function, cell metabolism and immune balance
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), 2025, in press
    DOI
  • Greșiță, Andrei; Hermann, Dirk M.; Boboc, Ianis Kevyn Stefan; Döppner, Thorsten R.; Petcu, Eugen; Semida, Ghinea Flavia; Popa-Wagner, Aurel
    Glial Cell Reprogramming in Ischemic Stroke : A Review of Recent Advancements and Translational Challenges
    In: Translational Stroke Research, Jg. 16, 2025, Nr. 5, S. 1811 – 1835
    DOI (Open Access)
  • Pirscoveanu, Denisa F. V.; Olaru, Denissa Greta; Hermann, Dirk M.; Döppner, Thorsten R.; Ghinea, Flavia Semida; Popa-Wagner, Aurel
    Immune genes involved in synaptic plasticity during early postnatal brain development contribute to post-stroke damage in the aging male rat brain
    In: Biogerontology, Jg. 26, 2025, Nr. 2, 60
    DOI
  • Grigore, Monica; Gresita, Andrei; Hermann, Dirk M.; Döppner, Thorsten R.; Gheorman, Victor; Glavan, Daniela; Popa-Wagner, Aurel
    Regulation of circadian gene activity in fibroblasts from ADHD patients through Rosiglitazone : a pilot study
    In: Journal of Neural Transmission, Jg. 132, 2025, Nr. 5, S. 709 – 721
    DOI
  • Burdusel, Daiana; Döppner, Thorsten R.; Surugiu, Roxana; Hermann, Dirk M.; Olaru, Denissa Greta; Popa-Wagner, Aurel
    The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches
    In: Biomolecules, Jg. 15, 2025, Nr. 1, 18
    DOI (Open Access)
  • Popa-Wagner, Aurel; Hermann, Dirk M.; Döppner, Thorsten R.; Surugiu, Roxana; Pirscoveanu, Denisa FV
    The age-associated decline in neuroplasticity and its implications for post-stroke recovery in animal models of cerebral ischemia : The therapeutic role of extracellular vesicles
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), 2025, in press
    DOI
  • Pirscoveanu, Denisa Floriana; Hermann, Dirk M.; Abuzan, Mihaela; Döppner, Thorsten R.; Martin, Liviu; Popa-Wagner, Aurel
    Vascular Aging and Multi-Omic Regulation in Ischemic Stroke : Toward Precision Neurorepair
    In: Aging and Disease, 2025, in press
    DOI (Open Access)
  • Luegering, Anneke; Langner, Robert; Wilm, Stefan; Döppner, Thorsten R.; Hermann, Dirk M.; Frohnhofen, Helmut; Gronewold, Janine
    Assessing self-administration of medication : video-based evaluation of patient performance in the ABLYMED study
    In: Frontiers in Medicine, Jg. 11, 2024, 1444567
    DOI, Online Volltext (Open Access)
  • Yin, Dongpei; Wang, Chen; Singh, Vikramjeet; Tuz, Ali Ata; Döppner, Thorsten R.; Gunzer, Matthias; Hermann, Dirk M.
    Delayed DNase-I Administration but Not Gasdermin-D Inhibition Induces Hemorrhagic Transformation after Transient Focal Cerebral Ischemia in Mice
    In: Stroke, Jg. 55, 2024, Nr. 11, S. e297 – e299
    DOI
  • Wei, Wei; Lattau, Seyed Siyawasch Justus; Xin, Wenqiang; Pan, Yongli; Tatenhorst, Lars; Zhang, Lin; Graf, Irina; Kuang, Yaoyun; Zheng, Xuan; Hao, Zhongnan; Popa-Wagner, Aurel; Gerner, Stefan T.; Huber, Sabine; Nietert, Manuel; Klose, Christian; Kilic, Ertugrul; Hermann, Dirk M.; Bähr, Mathias; Huttner, Hagen B.; Liu, Hua; Fitzner, Dirk; Döppner, Thorsten R.
    Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice
    In: Advanced Science, Jg. 11, 2024, Nr. 41, 2306863
    DOI (Open Access)
  • Wu, Nihong; Döppner, Thorsten R.; Hermann, Dirk M.; Gronewold, Janine
    Efficacy and safety of intravenous tenecteplase compared to alteplase before mechanical thrombectomy in acute ischemic stroke : a meta-analysis
    In: Journal of Neurology, Jg. 271, 2024, Nr. 7, S. 3928 – 3941
    DOI (Open Access)
  • Pan, Yongli; Xin, Wenqiang; Wei, Wei; Tatenhorst, Lars; Graf, Irina; Popa-Wagner, Aurel; Gerner, Stefan T.; Huber, Sabine E.; Kilic, Ertugrul; Hermann, Dirk M.; Bähr, Mathias; Huttner, Hagen B.; Döppner, Thorsten R.
    Knockdown of NEAT1 prevents post-stroke lipid droplet agglomeration in microglia by regulating autophagy
    In: Cellular and Molecular Life Sciences - CMLS, Jg. 81, 2024, Nr. 1, 30
    DOI (Open Access)
  • Ruscu, Mihai; Glavan, Daniela; Surugiu, Roxana; Döppner, Thorsten R.; Hermann, Dirk M.; Gresita, Andrei; Capitanescu, Bogdan; Popa-Wagner, Aurel
    Pharmacological and stem cell therapy of stroke in animal models : Do they accurately reflect the response of humans?
    In: Experimental Neurology, Jg. 376, 2024, 114753
    DOI (Open Access)
  • Dasdelen, Muhammed Furkan; Caglayan, Ahmet Burak; Er, Sezgin; Beker, Mustafa Caglar; Ates, Nilay; Gronewold, Janine; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Social isolation initiated post-weaning augments ischemic brain injury by promoting pro-inflammatory responses
    In: Experimental Neurology, Jg. 375, 2024, 114729
    DOI
  • Burdusel, Daiana; Coman, Cristin; Ancuta, Diana–Larisa; Hermann, Dirk M.; Döppner, Thorsten R.; Gresita, Andrei; Popa-Wagner, Aurel
    Translatability of life-extending pharmacological treatments between different species
    In: Aging Cell, Jg. 23, 2024, Nr. 7, e14208
    DOI (Open Access)
  • Beker, Mustafa C.; Aydinli, Fatmagul I.; Caglayan, Ahmet B.; Beker, Merve; Baygul, Oguzhan; Caglayan, Aysun; Popa-Wagner, Aurel; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Age-Associated Resilience Against Ischemic Injury in Mice Exposed to Transient Middle Cerebral Artery Occlusion
    In: Molecular Neurobiology, Jg. 60, 2023, Nr. 8, S. 4359 – 4372
    DOI
  • Gronewold, Janine; Jokisch, Martha; Schramm, Sara; Himpfen, Heiko; Ginster, Theresa; Tenhagen, Isabell; Döppner, Thorsten R.; Jockwitz, Christiane; Miller, Tatiana; Lehmann, Nils; Moebus, Susanne; Jöckel, Karl-Heinz; Erbel, Raimund; Caspers, Svenja; Hermann, Dirk M.
    Association of regional white matter hyperintensities with hypertension and cognition in the population-based 1000BRAINS study
    In: European Journal of Neurology, Jg. 30, 2023, Nr. 5, S. 1174 – 1190
    DOI (Open Access)
  • Scharf, Anne-Carina; Gronewold, Janine; Eilers, Andres; Todica, Olga; Moenninghoff, Christoph; Döppner, Thorsten R.; de Haan, Bianca; Bassetti, Claudio L.; Hermann, Dirk M.
    Depression and anxiety in acute ischemic stroke involving the anterior but not paramedian or inferolateral thalamus
    In: Frontiers in Psychology, Jg. 14, 2023, 1218526
    DOI (Open Access)
  • Luegering, Anneke; Langner, Robert; Wilm, Stefan; Döppner, Thorsten R.; Hermann, Dirk M.; Frohnhofen, Helmut; Gronewold, Janine
    Developing a novel tool to assess the ability to self-administer medication : A systematic evaluation of patients’ video recordings in the ABLYMED study
    In: Frontiers in Medicine, Jg. 10, 2023, 1040528
    DOI (Open Access)
  • Yin, Dongpei; Wang, Chen; Qi, Yachao; Wang, Ya-Chao; Hagemann, Nina; Mohamud Yusuf, Ayan; Dzyubenko, Egor; Kaltwasser, Britta; Tertel, Tobias; Giebel, Bernd; Gunzer, Matthias; Popa-Wagner, Aurel; Döppner, Thorsten R.; Hermann, Dirk M.
    Neural precursor cell delivery induces acute post-ischemic cerebroprotection, but fails to promote long-term stroke recovery in hyperlipidemic mice due to mechanisms that include pro-inflammatory responses associated with brain hemorrhages
    In: Journal of Neuroinflammation, Jg. 20, 2023, Nr. 1, 210
    DOI, Online Volltext (Open Access)
  • Pinosanu, Leonard Raul; Capitanescu, Bogdan; Glavan, Daniela; Godeanu, Sanziana; Ferna'ndez Cadenas, Israel; Döppner, Thorsten R.; Hermann, Dirk M.; Balseanu, Adrian-Tudor; Bogdan, Catalin; Popa-Wagner, Aurel
    Neuroglia Cells Transcriptomic in Brain Development, Aging and Neurodegenerative Diseases
    In: Aging and Disease, Jg. 14, 2023, Nr. 1, S. 63 – 83
    DOI, Online Volltext (Open Access)
  • Xin, Wenqiang; Pan, Yongli; Wei, Wei; Tatenhorst, Lars; Graf, Irina; Popa-Wagner, Aurel; Gerner, Stefan T.; Huber, Sabine; Kilic, Ertugrul; Hermann, Dirk M.; Bähr, Mathias; Huttner, Hagen B.; Döppner, Thorsten R.
    Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation
    In: Theranostics, Jg. 13, 2023, Nr. 12, S. 4197 – 4216
    DOI (Open Access)
  • Luegering, Anneke; Frohnhofen, Helmut; Langner, Robert; Wilm, Stefan; Döppner, Thorsten R.; Hermann, Dirk M.; Windolf, Joachim; Süss, Jan D.; Gronewold, Janine
    Problems in Medication Self-Management by Elderly Patients
    In: Deutsches Ärzteblatt International, Jg. 120, 2023, Nr. 33-34, S. 559 – 560
    DOI (Open Access)
  • Mayer, Geert; Stenmanns, Carla; Döppner, Thorsten R.; Hermann, Dirk M.; Gronewold, Janine
    Schlaf und Demenz
    In: Zeitschrift für Gerontologie und Geriatrie, Jg. 56, 2023, Nr. 7, S. 556 – 560
    DOI
  • Caglayan, Ahmet Burak; Beker, Mustafa Caglar; Sertel Evren, Elif; Caglayan, Berrak; Kilic, Ülkan; Ates, Nilay; Caglayan, Aysun; Dasdelen, Muhammed Furkan; Döppner, Thorsten R.; Saarma, Mart; Hermann, Dirk M.; Kilic, Ertugrul
    The Unconventional Growth Factors Cerebral Dopamine Neurotrophic Factor and Mesencephalic Astrocyte–Derived Neurotrophic Factor Promote Post-ischemic Neurological Recovery, Perilesional Brain Remodeling, and Lesion-Remote Axonal Plasticity
    In: Translational Stroke Research, Jg. 14, 2023, Nr. 2, S. 263 – 277
    DOI
  • Mohamud Yusuf, Ayan; Hagemann, Nina; Zhang, Xiaoni; Zafar, Maria; Hussner, Tanja; Bromkamp, Carolin; Martiny, Carlotta; Tertel, Tobias; Börger, Verena; Schumacher, Fabian; Solari, Fiorella A.; Hasenberg, Mike; Kleinschnitz, Christoph; Döppner, Thorsten R.; Kleuser, Burkhard; Sickmann, Albert; Gunzer, Matthias; Giebel, Bernd; Kolesnick, Richard; Gulbins, Erich; Hermann, Dirk M.
    Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles
    In: Basic Research in Cardiology, Jg. 117, 2022, Nr. 1, 43
    DOI (Open Access)
  • Zheng, X.; Zhang, L.; Kuang, Y.; Venkataramani, V.; Jin, F.; Hein, K.; Zafeiriou, M.P.; Lenz, C.; Moebius, W.; Kilic, E.; Hermann, Dirk M.; Weber, M.S.; Urlaub, H.; Zimmermann, W.-H.; Bähr, M.; Döppner, Thorsten R.
    Correction to: Extracellular Vesicles Derived from Neural Progenitor Cells : A Preclinical Evaluation for Stroke Treatment in Mice
    In: Translational Stroke Research, Jg. 13, 2022, Nr. 6, S. 1055 – 1055
    DOI (Open Access)
  • Hermann, Dirk M.; Xin, Wenqiang; Bähr, Mathias; Giebel, Bernd; Döppner, Thorsten R.
    Emerging roles of extracellular vesicle-associated non-coding RNAs in hypoxia : Insights from cancer, myocardial infarction and ischemic stroke
    In: Theranostics, Jg. 12, 2022, Nr. 13, S. 5776 – 5802
    DOI (Open Access)
  • Scharf, Anne-Carina; Gronewold, Janine; Todica, Olga; Mönninghoff, Christoph; Döppner, Thorsten R.; de Haan, Bianca; Bassetti, Claudio L.A.; Hermann, Dirk M.
    Evolution of Neuropsychological Deficits in First-Ever Isolated Ischemic Thalamic Stroke and Their Association With Stroke Topography : A Case-Control Study
    In: Stroke, Jg. 53, 2022, Nr. 6, S. 1904 – 1914
    DOI (Open Access)
  • Balçıkanlı, Zeynep; Culha, Irem; Dilsiz, Pelin; Aydin, Mehmet Serif; Ates, Nilay; Beker, Mustafa Caglar; Baltaci, Saltuk Bugra; Koc, Halil I.; Yigitbasi, Ahmet; Gündogar, Mustafa; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Lithium promotes long-term neurological recovery after spinal cord injury in mice by enhancing neuronal survival, gray and white matter remodeling, and long-distance axonal regeneration
    In: Frontiers in Cellular Neuroscience, Jg. 16, 2022, 1012523
    DOI (Open Access)
  • Döppner, Thorsten R.; Coman, Cristin; Burdusel, Daiana; Ancuta, Diana-Larisa; Brockmeier, Ulf; Pirici, Daniel Nicolae; Yaoyun, Kuang; Hermann, Dirk M.; Popa-Wagner, Aurel
    Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism
    In: Aging, Jg. 14, 2022, Nr. 10, S. 4195 – 4210
    DOI (Open Access)
  • Gronewold, Janine; Jokisch, Martha; Schramm, Sara; Himpfen, Heiko; Ginster, Theresa; Tenhagen, Isabell; Döppner, Thorsten R.; Jockwitz, Christiane; Miller, Tatiana; Lehmann, Nils; Moebus, Susanne; Jöckel, Karl-Heinz; Erbel, Raimund; Caspers, Svenja; Hermann, Dirk M.
    Periventricular rather than deep white matter hyperintensities mediate effects of hypertension on cognitive performance in the population-based 1000BRAINS study
    In: Journal of Hypertension, Jg. 40, 2022, Nr. 12, S. 2413 – 2422
    DOI (Open Access)
  • Beker, Mustafa C.; Caglayan, Ahmet B.; Altunay, Serdar; Ozbay, Elif; Ates, Nilay; Kelestemur, Taha; Caglayan, Berrak; Kilic, Ulkan; Doeppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Phosphodiesterase 10A Is a Critical Target for Neuroprotection in a Mouse Model of Ischemic Stroke
    In: Molecular Neurobiology, Jg. 59, 2022, S. 574 – 589
    DOI (Open Access)
  • Beker, Mustafa C.; Pence, Mahmud E.; Yagmur, Sumeyya; Caglayan, Berrak; Caglayan, Aysun; Kilic, Ulkan; Yelkenci, Hayriye E.; Altintas, Mehmet O.; Caglayan, Ahmet B.; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Phosphodiesterase 10A deactivation induces long-term neurological recovery, Peri-infarct remodeling and pyramidal tract plasticity after transient focal cerebral ischemia in mice
    In: Experimental Neurology, Jg. 358, 2022, 114221
    DOI
  • Ates, Nilay; Caglayan, Aysun; Balcikanli, Zeynep; Sertel, Elif; Beker, Mustafa Caglar; Dilsiz, Pelin; Caglayan, Ahmet Burak; Celik, Süleyman; Dasdelen, Muhammed Furkan; Caglayan, Berrak; Yigitbasi, Türkan; Ozbek, Hanefi; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
    In: Experimental Neurology, Jg. 351, 2022, 113996
    DOI
  • Silva de Carvalho, Tayana; Singh, Vikramjeet; Mohamud Yusuf, Ayan; Wang, Jing; Schultz Moreira, Adriana R.; Sanchez-Mendoza, Eduardo H.; Sardari, Maryam; Nascentes Melo, Luiza M.; Döppner, Thorsten R.; Kehrmann, Jan; Scholtysik, Rene; Hitpaß, Ludger; Gunzer, Matthias; Hermann, Dirk M.
    Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing
    In: Brain, Behavior and Immunity, Jg. 100, 2022, S. 134 – 144
    DOI (Open Access)
  • Wang, Chen; Börger, Verena; Mohamud Yusuf, Ayan; Tertel, Tobias; Stambouli, Oumaima; Murke, Florian; Freund, Nico; Kleinschnitz, Christoph; Herz, Josephine; Gunzer, Matthias; Popa-Wagner, Aurel; Döppner, Thorsten R.; Giebel, Bernd; Hermann, Dirk M.
    Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged Mice
    In: Stroke, Jg. 53, 2022, Nr. 1, S. E14 – E18
    DOI (Open Access)
  • Coliță, Daniela; Coliță, Cezar-Ivan; Hermann, Dirk M.; Coliță, Eugen; Döppner, Thorsten R.; Udristoiu, Ion; Popa-Wagner, Aurel
    Therapeutic Use and Chronic Abuse of CNS Stimulants and Anabolic Drugs
    In: Current Issues in Molecular Biology, Jg. 44, 2022, Nr. 10, S. 4902 – 4920
    DOI (Open Access)
  • Liu, Yunsheng; Wang, Xiaojun; Li, Xiangzhu; Qiao, Shanshan; Huang, Guodong; Hermann, Dirk M.; Döppner, Thorsten R.; Zeng, Muling; Liu, Wei; Xu, Gelin; Ren, Lijie; Zhang, Yuan; Liu, Wenlan; Casals, Eudald; Li, Weiping; Wang, Ya-Chao
    A Co-Doped Fe₃O₄Nanozyme Shows Enhanced Reactive Oxygen and Nitrogen Species Scavenging Activity and Ameliorates the Deleterious Effects of Ischemic Stroke
    In: ACS Applied Materials & Interfaces, Jg. 13, 2021, Nr. 39, S. 46213 – 46224
    DOI (Open Access)
  • Hermann, Dirk M.; Döppner, Thorsten R.; Giebel, Bernd
    Circulating MicroRNAs : Posttranscriptional Regulators and Disease Markers Holding Promise in Stroke Prediction
    In: Stroke, Jg. 52, 2021, Nr. 3, S. 954 – 956
    DOI (Open Access)
  • Zheng, X.; Zhang, L.; Kuang, Y.; Venkataramani, V.; Jin, F.; Hein, K.; Zafeiriou, M.P.; Lenz, C.; Moebius, W.; Kilic, E.; Hermann, Dirk M.; Weber, M.S.; Urlaub, H.; Zimmermann, W.-H.; Bähr, M.; Döppner, Thorsten R.
    Extracellular Vesicles Derived from Neural Progenitor Cells : a Preclinical Evaluation for Stroke Treatment in Mice
    In: Translational Stroke Research, Jg. 12, 2021, Nr. 1, S. 185 – 203
    DOI (Open Access)
  • Zhang, Lin; Wei, Wei; Ai, Xiaoyu; Kilic, Ertugrul; Hermann, Dirk M.; Venkataramani, Vivek; Bähr, Mathias; Döppner, Thorsten R.
    Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway
    In: Cell Death and Disease, Jg. 12, 2021, Nr. 11, 1068
    DOI (Open Access)
  • de Carvalho, Tayana Silva; Sanchez-Mendoza, Eduardo H.; Schultz Moreira, Adriana R.; Nascentes Melo, Luiza M.; Wang, Chen; Sardari, Maryam; Hagemann, Nina; Döppner, Thorsten R.; Kleinschnitz, Christoph; Hermann, Dirk M.
    Hypocaloric Diet Initiated Post-Ischemia Provides Long-Term Neuroprotection and Promotes Peri-Infarct Brain Remodeling by Regulating Metabolic and Survival-Promoting Proteins
    In: Molecular Neurobiology, Jg. 58, 2021, Nr. 4, S. 1491 – 1503
    DOI (Open Access)
  • Janssen, Lisa; Ai, Xiaoyu; Zheng, Xuan; Wei, Wei; Caglayan, Ahmet B.; Kilic, Ertugrul; Wang, Ya-Chao; Hermann, Dirk M.; Venkataramani, Vivek; Bähr, Mathias; Döppner, Thorsten R.
    Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model
    In: Frontiers in Cellular Neuroscience, Jg. 15, 2021, 733973
    DOI (Open Access)
  • Sardari, Maryam; Skuljec, Jelena; Yin, Dongpei; Zec, Kristina; de Carvalho, Tayana Silva; Albers, Dan; Wang, Chen; Pul, Refik; Popa-Wagner, Aurel; Döppner, Thorsten R.; Kleinschnitz, Christoph; Dzyubenko, Egor; Hermann, Dirk M.
    Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration
    In: Brain, Behavior and Immunity, Jg. 91, 2021, S. 627 – 638
    DOI (Open Access)
  • Haupt, Matteo; Zheng, Xuan; Kuang, Yaoyun; Lieschke, Simone; Janssen, Lisa; Bosche, Bert; Jin, Fengyan; Hein, Katharina; Kilic, Ertugrul; Venkataramani, Vivek; Hermann, Dirk M.; Bähr, Mathias; Döppner, Thorsten R.
    Lithium modulates miR‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation
    In: Stem Cells Translational Medicine, Jg. 10, 2021, Nr. 3, S. 357 – 373
    DOI (Open Access)
  • Zhang, Lin; Graf, Irina; Kuang, Yaoyun; Zheng, Xuan; Haupt, Matteo; Majid, Arshad; Kilic, Ertugrul; Hermann, Dirk M.; Psychogios, Marios-Nikos; Weber, Martin S.; Ochs, Jasmin; Bähr, Mathias; Döppner, Thorsten R.
    Neural Progenitor Cell-Derived Extracellular Vesicles Enhance Blood-Brain Barrier Integrity by NF-κB (Nuclear Factor-κB)-Dependent Regulation of ABCB1 (ATP-Binding Cassette Transporter B1) in Stroke Mice
    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Jg. 41, 2021, Nr. 3, S. 1127 – 1145
    DOI (Open Access)
  • Hermann, Dirk M.; Döppner, Thorsten R.; Giebel, Bernd
    New Light on the Horizon : Extracellular Vesicles as Diagnostic Tool in Transient Ischemic Attack and Ischemic Stroke
    In: Stroke, Jg. 52, 2021, Nr. 10, S. 3348 – 3350
    DOI (Open Access)
  • Gregorius, Jonas; Wang, Chen; Stambouli, Oumaima; Hussner, Tanja; Qi, Yachao; Tertel, Tobias; Börger, Verena; Yusuf, Ayan Mohamud; Hagemann, Nina; Yin, Dongpei; Dittrich, Robin; Mouloud, Yanis; Mairinger, Fabian D.; Magraoui, Fouzi El; Popa-Wagner, Aurel; Kleinschnitz, Christoph; Döppner, Thorsten R.; Gunzer, Matthias; Meyer, Helmut E.; Giebel, Bernd; Hermann, Dirk M.
    Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice
    In: Basic Research in Cardiology, Jg. 116, 2021, Nr. 1, 40
    DOI (Open Access)
  • Zheng, Xuan; Hermann, Dirk M.; Bähr, Mathias; Döppner, Thorsten R.
    The role of small extracellular vesicles in cerebral and myocardial ischemia : Molecular signals, treatment targets, and future clinical translation
    In: Stem Cells, Jg. 39, 2021, Nr. 4, S. 403 – 413
    DOI (Open Access)
  • Kuang, Yaoyun; Zheng, Xuan; Zhang, Lin; Ai, Xiaoyu; Venkataramani, Vivek; Kilic, Ertugrul; Hermann, Dirk M.; Majid, Arshad; Bähr, Mathias; Döppner, Thorsten R.
    Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25
    In: Journal of Extracellular Vesicles (JEV), Jg. 10, 2020, Nr. 1, S. e12024
    DOI (Open Access)
  • Lieschke, Simone; Zechmeister, Bozena; Haupt, Matteo; Zheng, Xuan; Jin, Fengyan; Hein, Katharina; Weber, Martin S.; Hermann, Dirk M.; Bähr, Mathias; Kilic, Ertugrul; Döppner, Thorsten R.
    CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age
    In: Cells, Jg. 9, 2020, Nr. 1, 66
    DOI (Open Access)
  • Danielyan, Lusine; Schwab, Matthias; Siegel, Georg; Brawek, Bianca; Garaschuk, Olga; Asavapanumas, Nithi; Buadze, Marine; Lourhmati, Ali; Wendel, Hans-Peter; Avci-Adali, Meltem; Krueger, Marcel A.; Calaminus, Carsten; Naumann, Ulrike; Winter, Stefan; Schaeffeler, Elke; Spogis, Annett; Beer-Hammer, Sandra; Neher, Jonas J.; Spohn, Gabriele; Kretschmer, Anja; Krämer-Albers, Eva-Maria; Barth, Kerstin; Lee, Hong Jun; Kim, Seung U.; Frey, William H.; Claussen, Claus D.; Hermann, Dirk M.; Döppner, Thorsten R.; Seifried, Erhard; Gleiter, Christoph H.; Northoff, Hinnak; Schäfer, Richard
    Cell motility and migration as determinants of stem cell efficacy
    In: eBioMedicine, Jg. 60, 2020, 102989
    DOI (Open Access)
  • Bosche, Bert; Mergenthaler, Philipp; Döppner, Thorsten R.; Hescheler, Jürgen; Molcanyi, Marek
    Complex Clearance Mechanisms After Intraventricular Hemorrhage and rt-PA Treatment : a Review on Clinical Trials
    In: Translational Stroke Research, Jg. 11, 2020, Nr. 3, S. 337 – 344
    DOI
  • Haupt, Matteo; Zechmeister, Bozena; Bosche, Bert; Lieschke, Simone; Zheng, Xuan; Zhang, Lin; Venkataramani, Vivek; Jin, Fengyan; Hein, Katharina; Weber, Martin S.; Hermann, Dirk M.; Bähr, Mathias; Döppner, Thorsten R.
    Lithium enhances post-stroke blood-brain barrier integrity, activates the MAPK/ERK1/2 pathway and alters immune cell migration in mice
    In: Neuropharmacology, Jg. 181, 2020, S. 108357
    DOI (Open Access)
  • Wang, Chen; Börger, Verena; Sardari, Maryam; Murke, Florian; Skuljec, Jelena; Pul, Refik; Hagemann, Nina; Dzyubenko, Egor; Dittrich, Robin; Gregorius, Jonas; Hasenberg, Mike; Kleinschnitz, Christoph; Popa-Wagner, Aurel; Döppner, Thorsten R.; Gunzer, Matthias; Giebel, Bernd; Hermann, Dirk M.
    Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils
    In: Stroke, Jg. 9, 2020, Nr. 10, S. 1825 – 1834
    DOI (Open Access)
  • Schäfer, Richard; Schwab, Matthias; Siegel, Georg; von Ameln-Mayerhofer, Andreas; Buadze, Marine; Lourhmati, Ali; Wendel, Hans-Peter; Kluba, Torsten; Krueger, Marcel A.; Calaminus, Carsten; Scheer, Eva; Dominici, Massimo; Grisendi, Giulia; Döppner, Thorsten R.; Schlechter, Jana; Finzel, Anne Kathrin; Gross, Dominic; Klaffschenkel, Roland; Gehring, Frank K.; Spohn, Gabriele; Kretschmer, Anja; Bieback, Karen; Krämer-Albers, Eva-Maria; Barth, Kerstin; Eckert, Anne; Elser, Stefanie; Schmehl, Joerg; Claussen, Claus D.; Seifried, Erhard; Hermann, Dirk M.; Northoff, Hinnak; Danielyan, Lusine
    Modulating endothelial adhesion and migration impacts stem cell therapies efficacy
    In: eBioMedicine, Jg. 60, 2020, 102987
    DOI (Open Access)
  • Caglayan, Ahmet B.; Beker, Mustafa C.; Caglayan, Berrak; Yalcin, Esra; Caglayan, Aysun; Yulug, Burak; Hanoglu, Lutfu; Kutlu, Selim; Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul
    Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
    In: Frontiers in Cellular Neuroscience, Jg. 13, 2019, S. 144
    DOI (Open Access)
  • Hermann, Dirk M.; Popa-Wagner, Aurel; Kleinschnitz, Christoph; Döppner, Thorsten R.
    Animal models of ischemic stroke and their impact on drug discovery
    In: Expert Opinion on Drug Discovery, Jg. 14, 2019, Nr. 3, S. 315 – 326
    DOI
  • Manrique-Castano, Daniel; Sardari, Maryam; Silva de Carvalho, Tayana; Döppner, Thorsten R.; Popa-Wagner, Aurel; Kleinschnitz, Christoph; Chan, Andrew; Hermann, Dirk M.
    Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes
    In: Frontiers in Cellular Neuroscience, Jg. 13, 2019, S. 412
    DOI, Online Volltext (Open Access)
  • Jin, Fengyan; Zheng, Xiangyu; Yang, Yanping; Yao, Gang; Ye, Long; Döppner, Thorsten R.; Hermann, Dirk M.; Wang, Haifeng; Dai, Yun
    Impairment of hypoxia-induced angiogenesis by LDL involves a HIFcentered signaling network linking inflammatory TNFα and angiogenic VEGF
    In: Aging, Jg. 11, 2019, Nr. 2, S. 328 – 349
    DOI, Online Volltext (Open Access)
  • Hermann, Dirk M.; Döppner, Thorsten R.; Popa-Wagner, Aurel
    Opportunities and Limitations of Vascular Risk Factor Models in Studying Plasticity-Promoting and Restorative Ischemic Stroke Therapies
    In: Neural Plasticity, 2019, S. 9785476
    DOI (Open Access)
  • Bieber, Michael; Gronewold, Janine; Scharf, Anne-Carina; Schuhmann, Michael K.; Langhauser, Friederike; Hopp, Sarah; Mencl, Stine; Geuss, Eva; Leinweber, Jonas; Guthmann, Josua; Döppner, Thorsten R.; Kleinschnitz, Christoph; Stoll, Guido; Kraft, Peter; Hermann, Dirk M.
    Validity and Reliability of Neurological Scores in Mice Exposed to Middle Cerebral Artery Occlusion
    In: Stroke, Jg. 50, 2019, Nr. 10, S. 2875 – 2882
    DOI (Open Access)
  • Döppner, Thorsten R.; Herz, Josephine; Bähr, Mathias; Tonchev, Anton B.; Stoykova, Anastassia
    Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury
    In: Molecular Neurobiology, Jg. 56, 2019, Nr. 1, S. 567 – 582
    DOI
  • Jin, Fengyan; Hagemann, Nina; Sun, Li; Wu, Jiang; Döppner, Thorsten R.; Dai, Yun; Hermann, Dirk M.
    High-density lipoprotein (HDL) promotes angiogenesis via S1P3-dependent VEGFR2 activation
    In: Angiogenesis, Jg. 21, 2018, Nr. 2, S. 381 – 394
    DOI
  • Döppner, Thorsten R.; Bähr, Mathias; Giebel, Bernd; Hermann, Dirk M.
    Immunological and non-immunological effects of stem cell-derived extracellular vesicles on the ischaemic brain
    In: Therapeutic Advances in Neurological Disorders, Jg. 11, 2018
    DOI (Open Access)
  • Wang, Ya-Chao; Dzyubenko, Egor; Sanchez-Mendoza, Eduardo H.; Sardari, Maryam; Silva de Carvalho, Tayana; Döppner, Thorsten R.; Kaltwasser, Britta; Machado, Patricia; Kleinschnitz, Christoph; Bassetti, Claudio L.; Hermann, Dirk M.
    Postacute Delivery of GABA A α5 Antagonist Promotes Postischemic Neurological Recovery and Peri-infarct Brain Remodeling
    In: Stroke, Jg. 49, 2018, Nr. 10, S. 2495 – 2503
    DOI (Open Access)
  • Ludwig, Anna-Kristin; De Miroschedji, Kyra; Döppner, Thorsten R.; Börger, Verena; Ruesing, Johannes; Rebmann, Vera; Durst, Stephan; Jansen, Sören; Bremer, Michel; Behrmann, Elmar; Singer, Bernhard B.; Jastrow, Holger; Kuhlmann, Jan Dominik; El Magraoui, Fouzi; Meyer, Helmut E.; Hermann, Dirk M.; Opalka, Bertram; Raunser, Stefan; Epple, Matthias; Horn, Peter; Giebel, Bernd
    Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales
    In: Journal of Extracellular Vesicles (JEV), Jg. 7, 2018, Nr. 1, S. 1528109
    DOI (Open Access)
  • Döppner, Thorsten R.; Zechmeister, Bozena; Kaltwasser, Britta; Jin, Fengyan; Zheng, Xuan; Majid, Arshad; Venkataramani, Vivek; Bähr, Mathias; Hermann, Dirk M.
    Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppression Reversal
    In: Frontiers in Cellular Neuroscience, Jg. 12, 2018, S. 383
    DOI (Open Access)
  • Döppner, Thorsten R.; Bähr, Mathias; Hermann, Dirk M.; Giebel, Bernd
    Concise Review : Extracellular Vesicles Overcoming Limitations of Cell Therapies in Ischemic Stroke
    In: Stem Cells Translational Medicine, Jg. 6, 2017, Nr. 11, S. 2044 – 2052
    DOI (Open Access)
  • Döppner, Thorsten R.; Traut, Viktorija; Heidenreich, Alexander; Kaltwasser, Britta; Bosche, Bert; Bähr, Mathias; Hermann, Dirk M.
    Conditioned Medium Derived from Neural Progenitor Cells Induces Long-term Post-ischemic Neuroprotection, Sustained Neurological Recovery, Neurogenesis, and Angiogenesis
    In: Molecular Neurobiology, Jg. 54, 2017, Nr. 2, S. 1531 – 1540
    DOI
  • Wang, Xue; Yao, Gang; Döppner, Thorsten R.; Dai, Yun; Hermann, Dirk M.; Sun, Yue; Wu, Chuan; Chen, Kexin; Wang, Siqing; Tong, Qian; Li, Haixia; Jin, Fengyan; Yu, Dehai; Wu, Jiang; Ye, Long
    Identification of the histone lysine demethylase KDM4A/JMJD2A as a novel epigenetic target in M1 macrophage polarization induced by oxidized LDL
    In: OncoTarget, Jg. 8, 2017, Nr. 70, S. 114442 – 114456
    DOI (Open Access)
  • Döppner, Thorsten R.; Doehring, Maria; Kaltwasser, Britta; Majid, Arshad; Lin, Fengyan; Bähr, Mathias; Kilic, Ertugrul; Hermann, Dirk M.
    Ischemic post-conditioning induces post-stroke neuroprotection via Hsp70-Mediated proteasome inhibition and facilitates neural progenitor cell transplantation
    In: Molecular Neurobiology, Jg. 54, 2017, Nr. 8, S. 6061 – 6073
    DOI
  • Döppner, Thorsten R.; Kaltwasser, Britta; Sanchez-Mendoza, Eduardo H; Caglayan, Ahmet B; Bähr, Mathias; Hermann, Dirk M.
    Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), Jg. 37, 2017, Nr. 3, S. 914 – 926
    DOI, Online Volltext (Open Access)
  • Wang, Ya-Chao; Sanchez-Mendoza, Eduardo H; Döppner, Thorsten R.; Hermann, Dirk M.
    Post-Acute delivery of memantine promotes post-ischemic neurological recovery, peri-infarct tissue remodeling, and contralesional brain plasticity
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), Jg. 37, 2017, Nr. 3, S. 980 – 993
    DOI, Online Volltext (Open Access)
  • Sánchez-Mendoza, Eduardo H.; Bellver-Landete, Victor; Arce, Carmen; Döppner, Thorsten R.; Hermann, Dirk M.; Oset-Gasque, María Jesús
    Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZ-derived neural precursor cells
    In: PLoS ONE, Jg. 12, 2017, Nr. 5, S. e0177069
    DOI (Open Access)
  • Bosche, Bert; Härtel, Frauke V.; Loch Macdonald, R.; Müller, Daniel J.; Hescheler, Jürgen; Döppner, Thorsten R.; Zatschler, Birgit; Rej, Soham; Noll, Thomas; Molcanyi, Marek
    A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation
    In: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Jg. 67, 2016, S. 98 – 106
    DOI
  • Sanchez-Mendoza, Eduardo H.; Carballo, Jeismar; Longart, Marines; Hermann, Dirk M.; Döppner, Thorsten R.
    Implantation of miniosmotic pumps and delivery of tract tracers to study brain reorganization in pathophysiological conditions
    In: JoVE, Jg. 2016, 2016, Nr. 107, S. e52932
    DOI (Open Access)
  • Bosche, Bert; Molcanyi, Marek; Rej, Soham; Döppner, Thorsten R.; Obermann, Mark; Müller, Daniel J.; Das, Anupam; Hescheler, Jürgen; Loch Macdonald, R.; Noll, Thomas; Härtel, Frauke V.
    Low-dose lithium stabilizes human endothelial barrier by decreasing MLC phosphorylation and universally augments cholinergic vasorelaxation capacity in a direct manner
    In: Frontiers in Physiology, Jg. 7, 2016, S. 00593
    DOI (Open Access)
  • Döppner, Thorsten R.; Hermann, Dirk M.; Kilic, Ertugrul; Bretschneider, Eva; Henkelein, Petra; Kuckelkorn, Ulrike; Kaltwasser, Britta
    Systemic Proteasome Inhibition Induces Sustained Post-stroke Neurological Recovery and Neuroprotection via Mechanisms Involving Reversal of Peripheral Immunosuppression and Preservation of Blood–Brain–Barrier Integrity
    In: Molecular Neurobiology, Jg. 53, 2016, Nr. 9, S. 6332 – 6341
    DOI
  • Zang, Meirong; Li, Zengjun; Liu, Lanting; Li, Fei; Li, Xin; Dai, Yun; Li, Wei; Kuckelkorn, Ulrike; Döppner, Thorsten R.; Hermann, Dirk M.; Zhou, Wen; Qiu, Lugui; Jin, Fengyan
    Anti-tumor activity of the proteasome inhibitor BSc2118 against human multiple myeloma
    In: Cancer Letters, Jg. 366, 2015, Nr. 2, S. 173 – 181
    DOI
  • Döppner, Thorsten R.; Kaltwasser, Britta; Schlechter, J.; Jaschke, J.; Kilic, E.; Bähr, M.; Hermann, Dirk M.; Weise, J.
    Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition
    In: Cell Death and Disease, Jg. 6, 2015, Nr. 12, e2024
    DOI (Open Access)
  • Döppner, Thorsten R.; Herz, Josephine; Görgens, André; Schlechter, Jana; Ludwig, Anna-Kristin; Radtke, Stefan; de Miroschedji, Kyra; Horn, Peter; Giebel, Bernd; Hermann, Dirk M.
    Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
    In: Stem Cells Translational Medicine, Jg. 4, 2015, Nr. 10, S. 1131 – 1143
    DOI (Open Access)
  • Yao, Gang; Zhang, Qi; Döppner, Thorsten R.; Niu, Feng; Li, Qiaochuan; Yang, Yanping; Kuckelkorn, Ulrike; Hagemann, Nina; Li, Wei; Hermann, Dirk; Dai, Yun; Zhou, Wen; Jin, Fengyan
    LDL suppresses angiogenesis through disruption of the HIF pathway via NF-κB inhibition which is reversed by the proteasome inhibitor BSc2118
    In: OncoTarget, Jg. 6, 2015, Nr. 30, S. 30251 – 30262
    DOI (Open Access)
  • Döppner, Thorsten R.; Kaltwasser, Britta; Teli, Mahesh K.; Sanchez-Mendoza, Eduardo H.; Kilic, Ertugrul; Bähr, Mathias; Hermann, Dirk M.
    Post-stroke transplantation of adult subventricular zone derived neural progenitor cells : a comprehensive analysis of cell delivery routes and their underlying mechanisms
    In: Experimental Neurology, Jg. 273, 2015, S. 45 – 56
    DOI
  • Herz, Josephine; Sabellek, Pascal; Lane, Thomas E; Gunzer, Matthias; Hermann, Dirk M.; Döppner, Thorsten R.
    Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice
    In: Stroke, Jg. 46, 2015, Nr. 10, S. 2916 – 2925
    DOI (Open Access)
  • Hermann, Dirk; Zechariah, Anil; Kaltwasser, Britta; Bosche, Bert; Caglayan, Ahmet B.; Kilic, Ertugrul; Döppner, Thorsten R.
    Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia
    In: Neurobiology of Disease, Jg. 83, 2015, S. 16 – 25
    DOI
  • Döppner, Thorsten R.; Pehlke, Jens R.; Kaltwasser, Britta; Schlechter, Jana; Kilic, Ertuǧrul; Bähr, Mathias; Hermann, Dirk M.
    The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), Jg. 35, 2015, Nr. 12, S. 2089 – 2097
    DOI (Open Access)
  • Jaeger, Hanna M.; Pehlke, Jens R.; Kaltwasser, Britta; Kilic, Ertugrul; Bähr, Mathias; Hermann, Dirk M.; Döppner, Thorsten R.
    The indirect NMDAR inhibitor flupirtine induces sustained post-ischemic recovery, neuroprotection and angioneurogenesis.
    In: OncoTarget, Jg. 6, 2015, Nr. 16, S. 14033 – 14044
    DOI (Open Access)
  • Neumann, Jens; Riek-Burchardt, Monika; Herz, Josephine; Döppner, Thorsten R.; König, Rebecca; Hütten, Heiko; Etemire, Eloho; Männ, Linda; Klingberg, Anika; Fischer, Thomas; Görtler, Michael W; Heinze, Hans-Jochen; Reichardt, Peter; Schraven, Burkhart; Hermann, Dirk M.; Reymann, Klaus G; Gunzer, Matthias
    Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke
    In: Acta Neuropathologica, Jg. 129, 2015, Nr. 2, S. 259 – 277
    DOI
  • Młynarczuk-Biały, Izabela; Döppner, Thorsten R.; Goła̧b, Jakub; Nowis, Dominika Anna; Wilczyñski, Grzegorz Marek; Parobczak, Kamil; Wigand, Moritz E.; Hajdamowicz, Malgorzata; Biały, Łukasz P.; Aniolek, Olga; Henklein, Petra; Bähr, Mathias J.; Schmidt, Boris; Kuckelkorn, Ulrike; Kloetzel, Peter Michael
    Biodistribution and efficacy studies of the proteasome inhibitor BSc2118 in a mouse melanoma model
    In: Translational Oncology, Jg. 7, 2014, Nr. 5, S. 570 – 579
    DOI (Open Access)
  • Döppner, Thorsten R.; Kaltwasser, B; Teli, M K; Bretschneider, E; Bähr, M; Hermann, Dirk M.
    Effects of acute versus post-acute systemic delivery of neural progenitor cells on neurological recovery and brain remodeling after focal cerebral ischemia in mice
    In: Cell Death and Disease, Jg. 5, 2014, Nr. 8, e1386
    DOI (Open Access)
  • Döppner, Thorsten R.; Kaltwasser, Britta; Bähr, Mathias; Hermann, Dirk M.
    Effects of neural progenitor cells on post-stroke neurological impairment : a detailed and comprehensive analysis of behavioral tests
    In: Frontiers in Cellular Neuroscience, Jg. 8, 2014, Nr. Oct., Art. 338
    DOI (Open Access)
  • Herz, Josephine; Hagen, Sabine I; Bergmüller, Eileen; Sabellek, Pascal; Göthert, Joachim Rudolf; Buer, Jan; Hansen, Wiebke; Hermann, Dirk M.; Döppner, Thorsten R.
    Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responses
    In: Neurobiology of Disease, Jg. 62, 2014, S. 456 – 468
    DOI
  • Kordelas, L; Rebmann, Vera; Ludwig, A-K; Radtke, Stefan; Ruesing, J; Döppner, Thorsten R.; Epple, Matthias; Horn, Peter; Beelen, Dietrich; Giebel, Bernd
    MSC-derived exosomes : a novel tool to treat therapy-refractory graft-versus-host disease
    In: Leukemia, Jg. 28, 2014, Nr. 4, S. 970 – 973
    DOI
  • Hermann, Dirk M.; Peruzzotti-Jametti, Luca; Schlechter, Jana; Bernstock, Joshua D; Döppner, Thorsten R.; Pluchino, Stefano
    Neural precursor cells in the ischemic brain - integration, cellular crosstalk, and consequences for stroke recovery
    In: Frontiers in Cellular Neuroscience, Jg. 8, 2014, S. 291
    DOI (Open Access)
  • Herz, Josephine; Sabellek, P.; Hermann, Dirk M.; Döppner, Thorsten R.
    Neuroprotection by blocking CXCR2 after cerebral ischemia in hypercholesterolemic mice
    In: Journal of Neuroimmunology, Jg. 275, 2014, Nr. 1-2, S. 152 – 153
    DOI
  • Popa-Wagner, Aurel; Buga, Ana-Maria; Döppner, Thorsten R.; Hermann, Dirk M.
    Stem cell therapies in preclinical models of stroke associated with aging
    In: Frontiers in Cellular Neuroscience, Jg. 8, 2014, S. 347
    DOI (Open Access)
  • Döppner, Thorsten R.; Hermann, Dirk
    Stem cell-based treatments against stroke : observations from human proof-of-concept studies and considerations regarding clinical applicability
    In: Frontiers in Cellular Neuroscience, Jg. 8, 2014, Nr. 357
    DOI (Open Access)
  • Zechariah, Anil; Jin, Fengyan; Hagemann, Nina; Döppner, Thorsten R.; ElAli, Ayman; Helfrich, Iris; Mies, Günter; Hermann, Dirk M.
    Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells
    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Jg. 33, 2013, Nr. 7, S. 1561 – 1567
    DOI
  • Hasan, Mohammad R; Herz, Josephine; Hermann, Dirk M.; Döppner, Thorsten R.
    Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels
    In: JoVE, 2013, Nr. 71, S. e4374
    DOI, Online Volltext (Open Access)
  • Döppner, Thorsten R.; Doehring, Maria; Bretschneider, Eva; Zechariah, Anil; Kaltwasser, Britta; Müller, Barbara; Koch, Jan C.; Bähr, Mathias; Hermann, Dirk M.; Michel, Uwe
    MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation
    In: Acta Neuropathologica, Jg. 126, 2013, Nr. 2, S. 251 – 265
    DOI
  • Döppner, Thorsten R.; Kaltwasser, Britta; Fengyan, Jin; Hermann, Dirk M.; Bähr, Mathias
    TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), Jg. 33, 2013, Nr. 11, S. 1778 – 1788
    DOI, Online Volltext (Open Access)
  • Zechariah, Anil; ElAli, Ayman; Döppner, Thorsten R.; Jin, Fengyan; Hasan, Mohammad R.; Helfrich, Iris; Mies, Günter; Hermann, Dirk M.
    Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra
    In: Stroke, Jg. 44, 2013, Nr. 6, S. 1690 – 1697
    DOI
  • Herz, Josephine; Hagen, S. I.; Hermann, Dirk M.; Döppner, Thorsten R.
    Acute peripheral and CNS immune responses in hypercholesterolemic mice after mild brain ischemia
    In: Journal of Neuroimmunology, Jg. 253, 2012, Nr. 1-2, S. 99
  • Elali, Ayman; Urrutia, Andrés; Rubio-Araiz, Ana; Hernandez-Jimenez, MacArena; Colado, Maria I.; Döppner, Thorsten R.; Hermann, Dirk M.
    Apolipoprotein-E Controls Adenosine Triphosphate-Binding Cassette Transporters ABCB1 and ABCC1 on Cerebral Microvessels After Methamphetamine Intoxication
    In: Stroke, Jg. 43, 2012, Nr. 6, S. 1647 – 1653
    DOI (Open Access)
  • ElAli, A.; Urrutia, A.; Rubio-Araiz, A.; Hernandez-Jimenez, M.; Colado, M. I.; Döppner, Thorsten R.; Hermann, Dirk M.
    Apolipoprotein-E controls ATP-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication
    In: European Journal of Neurology, Jg. 19, 2012, Nr. Suppl. 1, S. 489
  • Herz, Josephine; Reitmeir, Raluca; Hagen, Sabine I.; Reinboth, Barbara S.; Guo, Zeyun; Zechariah, Anil; ElAli, Ayman; Döppner, Thorsten R.; Bacigaluppi, Marco; Pluchino, Stefano; Kilic, Ülkan; Kilic, Ertugrul; Hermann, Dirk M.
    Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions
    In: Neurobiology of Disease, Jg. 45, 2012, Nr. 3, S. 1077 – 1085
    DOI
  • Hasan, M. R.; Herz, Josephine; Hermann, Dirk M.; Döppner, Thorsten R.
    Intravascular perfusion of carbon black ink allows reliable visualization of cerebral vessels in mice
    In: European Journal of Neurology, Jg. 19, 2012, Nr. Suppl. 1, S. 185
  • Döppner, Thorsten R.; Mlynarczuk-Bialy, Izabela; Kuckelkorn, Ulrike; Kaltwasser, Britta; Herz, Josephine; Hasan, Mohammad R.; Hermann, Dirk M.; Bähr, Mathias
    The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis
    In: Brain: A Journal of Neurology, Jg. 135, 2012, Nr. 11, S. 3282 – 3297
    DOI
  • Döppner, Thorsten R.; Ewert, Tobias A. S.; Tönges, Lars; Herz, Josephine; Zechariah, Anil; ElAli, Ayman; Ludwig, Anna-Kristin; Giebel, Bernd; Nagel, Florian; Dietz, Gunnar P. H.; Weise, Jens; Hermann, Dirk M.; Bähr, Mathias
    Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone : Therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation
    In: Stem Cells, Jg. 30, 2012, Nr. 6, S. 1297 – 1310
    DOI
  • Hasan, Mohammad R.; Herz, Josephine; Hermann, Dirk M.; Döppner, Thorsten R.
    Visualization of macroscopic cerebral vessel anatomy—A new and reliable technique in mice
    In: Journal of Neuroscience Methods, Jg. 204, 2012, Nr. 2, S. 249 – 253
    DOI
  • Döppner, Thorsten R.; Kaltwasser, Britta; ElAli, Ayman; Zechariah, Anil; Hermann, Dirk M.; Bähr, Mathias
    Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM), Jg. 31, 2011, Nr. 5, S. 1251 – 1262
    DOI
  • Döppner, Thorsten R.; Bretschneider, Eva; Doehring, Maria; Segura, Inmaculada; Sentürk, Aycan; Acker-Palmer, Amparo; Hasan, Mohammad R.; Elali, Ayman; Hermann, Dirk M.; Bähr, Mathias
    Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia
    In: Acta Neuropathologica, Jg. 122, 2011, Nr. 4, S. 429 – 442
    DOI (Open Access)
  • Elali, Ayman; Döppner, Thorsten R.; Zechariah, Anil; Hermann, Dirk M.
    Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia : Role of lipid peroxidation and calpain-1/2, matrix metalloproteinase-2/9, and rhoa overactivation
    In: Stroke, Jg. 42, 2011, Nr. 11, S. 3238 – 3244
    DOI
  • Döppner, Thorsten R.; Hermann, Dirk M.
    Free radical scavengers and spin traps – therapeutic implications for ischemic stroke
    In: Best Practice and Research Clinical Anaesthesiology, Jg. 24, 2010, Nr. 4, S. 511 – 520
    DOI

    • Vorworte / Nachworte

  • Döppner, Thorsten R.; Hermann, Dirk
    Editorial : Stem cells and progenitor cells in ischemic stroke—fashion or future?
    In: Frontiers in Cellular Neuroscience. Lausanne: Frontiers Media, Jg. 9, 2015, Nr. August, S. 334
    DOI (Open Access)

    • Abstracts

  • Yamashita, Toru; Döppner, Thorsten R.; Borlongan, Cesar; Niizuma, Kuniyasu; Pluchino, Stefano; Hermann, Dirk M.
    Translational strategies for application of stem cells and their extracellular vesicles as modulators of post-stroke neuroregeneration
    BRAIN & BRAIN PET 2022 ; 29 May – 1 June 2022, Glasgow, UK,
    In: Journal of Cerebral Blood Flow and Metabolism (JCBFM). Thousands Oaks: Sage, Jg. 42, 2022, Nr. Supplement 1, S. 283 – 284
    DOI, Online Volltext (Open Access)
  • Döppner, Thorsten R.; Herz, Josephine; Görgens, A.; Schlechter, J.; Ludwig, A. K.; de Mirochedji, K.; Giebel, Bernd; Hermann, Dirk M.
    Exosomes reduce brain injury in a rodent stroke model via immunomodulatory actions and stimulation of post-ischemic neuroregeneration
    Joint Congress of European Neurology 31 May–3 June 2014 Istanbul, Turkey,
    In: Journal of Neurology. Berlin; Leipzig: Springer, Jg. 261, 2014, Nr. Suppl. 1, S. 70
    DOI
  • Döppner, Thorsten R.; Herz, Josephine; Gorgens, A.; Schlechter, J.; Ludwig, A. K.; de Mirochedji, K.; Giebel, Bernd; Hermann, Dirk M.
    Exosomes reduce brain injury in a rodent stroke model via immunomodulatory actions and stimulation of post-ischemic neuroregeneration
    Joint Congress of European Neurology, Istanbul, Turkey, May 2014,
    In: European Journal of Neurology. Hoboken: Wiley, Jg. 21, 2014, Nr. Suppl. 1, S. 97
    DOI
  • Döppner, Thorsten R.; Kaltwasser, B.; Teli, M. K.; Hermann, Dirk M.
    Treating experimental stroke with adult neural progenitor cells : an analysis of optimal intravenous cell delivery time points and their underlying mechanisms
    Joint Congress of European Neurology 31 May–3 June 2014 Istanbul, Turkey,
    In: Journal of Neurology. Berlin; Leipzig: Springer, Jg. 261, 2014, Nr. Suppl. 1, S. S84 – S85
    DOI
  • Döppner, Thorsten R.; Kaltwasser, B.; Teli, M. K.; Hermann, Dirk M.
    Treating experimental stroke with adult neural progenitor cells - an analysis of optimal intravenous cell delivery time points and their underlying mechanisms
    Joint Congress of European Neurology, Istanbul, Turkey, May 2014,
    In: European Journal of Neurology. Hoboken: Wiley, Jg. 21, 2014, Nr. Suppl. 1, S. 117
    DOI
  • ElAli, A.; Döppner, Thorsten R.; Zechariah, A.; Hermann, Dirk M.
    Increased Blood-Brain barrier permeability and brain Oedema aftrer focal cerebral Ischaemia induced by Hyperlipidemia : ROole of Lipid Peroxidation and Calpaon-1/2, Matrix Metalloproteinase-2/9 and RhoA Overactivation
    15th Congress of the European Federation of Neurological Societies (EFNS). September 11-13, 2011. Budapest, Hungary,
    In: European Journal of Neurology. Hoboken: Wiley, Jg. 18, 2011, Nr. Suppl. 2, S. 123
    DOI

    • Bücher/Sammelwerke/Tagungsbände

  • Döppner, Thorsten R.
    Zellbasierte Therapie des ischämischen Schlaganfalls : Modulation von endogener Neurogenese und Transplantation neuraler Vorläuferzellen im Schlaganfallmodell der Maus
    Duisburg, Essen, 2013

    • Dissertation

  • Döppner, Thorsten R.
    Untersuchungen zur Beteiligung von Proteasen an der kälteinduzierten Apoptose von Rattenleberendothelzellen
    Duisburg-Essen, 2005
    Online Volltext, Online Volltext