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Wiss. Mitarbeiterinnen/Mitarbeiter, Klinik für Nuklearmedizin
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistanceIn: Signal Transduction and Targeted Therapy, Jg. 10, 2025, Nr. 1, 319DOI (Open Access)
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EANM expert opinion: How can lessons from radiobiology be applied to the design of clinical trials? : Part I: back to the basics of absorbed dose–response and threshold absorbed dosesIn: European Journal of Nuclear Medicine and Molecular Imaging, Jg. 52, 2025, Nr. 3, S. 1210 – 1222DOI (Open Access)
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Optimizing peptide nucleic acid-based pretargeting for enhanced targeted radionuclide therapyIn: Journal of Controlled Release, Jg. 381, 2025, 113551DOI (Open Access)
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Detection of tumour heterogeneity in patients with advanced, metastatic castration-resistant prostate cancer on [⁶⁸Ga]Ga-/[¹⁸F]F-PSMA-11/-1007, [⁶⁸Ga]Ga-FAPI-46 and 2-[¹⁸F]FDG PET/CT : a pilot studyIn: European Journal of Nuclear Medicine and Molecular Imaging, Jg. 52, 2024, Nr. 1, S. 342 – 353DOI (Open Access)
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Evaluating [²²⁵Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in miceIn: European Journal of Nuclear Medicine and Molecular Imaging, Jg. 51, 2024, Nr. 13, S. 4026 – 4037DOI (Open Access)
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Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeuticsIn: European Journal of Medicinal Chemistry, Jg. 280, 2024, 116927DOI (Open Access)
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18F-PSMA Cerenkov Luminescence and Flexible Autoradiography Imaging in a Prostate Cancer Mouse Model and First Results of a Radical Prostatectomy Feasibility Study in MenIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 4, S. 598 – 604DOI (Open Access)
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Analysing the tumor transcriptome of prostate cancer to predict efficacy of Lu-PSMA therapyIn: Journal for ImmunoTherapy of Cancer, Jg. 11, 2023, Nr. 10, e007354DOI (Open Access)
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Fibroblast Activation Protein Inhibitor Theranostics : Preclinical Combination TreatmentIn: PET Clinics, Jg. 18, 2023, Nr. 3, S. 409 – 418
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Fibroblast-Activation Protein PET and Histopathology in a Single-Center Database of 324 Patients and 21 Tumor EntitiesIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 5, S. 711 – 716DOI (Open Access)
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Is There a Role of Artificial Intelligence in Preclinical Imaging?In: Seminars in Nuclear Medicine, Jg. 53, 2023, Nr. 5, S. 687 – 693
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Novel ⁶⁸Ga-FAPI PET/CT Offers Oncologic Staging Without COVID-19 Vaccine-Related PitfallsIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 3, S. 368 – 371DOI (Open Access)
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Oncologic Staging with ⁶⁸Ga-FAPI PET/CT Demonstrates a Lower Rate of Nonspecific Lymph Node Findings Than ¹⁸F-FDG PET/CTIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 12, S. 1906 – 1909DOI (Open Access)
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PSMA-Directed Imaging and Therapy of Salivary Gland Tumors : A Single-Center Retrospective StudyIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 3, S. 372 – 378DOI (Open Access)
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Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy ResponseIn: Molecular Cancer Research, Jg. 21, 2023, Nr. 4, S. 307 – 315DOI, Online Volltext (Open Access)
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Superior Tumor Detection for ⁶⁸Ga-FAPI-46 Versus ¹⁸F-FDG PET/CT and Conventional CT in Patients with CholangiocarcinomaIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 7, S. 1049 – 1055DOI (Open Access)
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Tandem Isotope Therapy with ²²⁵Ac- and ¹⁷⁷Lu-PSMA-617 in a Murine Model of Prostate CancerIn: Journal of Nuclear Medicine (JNM), Jg. 64, 2023, Nr. 11, S. 1772 – 1778DOI (Open Access)
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Administration Routes for SSTR-/PSMA- and FAP-Directed Theranostic Radioligands in MiceIn: Journal of Nuclear Medicine (JNM), Jg. 63, 2022, Nr. 9, S. 1357 – 1363DOI, Online Volltext (Open Access)
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Comparison of PSMA-TO-1 and PSMA-617 labeled with gallium-68, lutetium-177 and actinium-225In: EJNMMI Research, Jg. 12, 2022, Nr. 1, 65DOI (Open Access)
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Pitfalls and Common Findings in ⁶⁸Ga-FAPI PET : A Pictorial AnalysisIn: Journal of Nuclear Medicine (JNM), Jg. 63, 2022, Nr. 6, S. 890 – 896DOI (Open Access)
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Response to Combined Peptide Receptor Radionuclide Therapy and Checkpoint Immunotherapy with Ipilimumab Plus Nivolumab in Metastatic Merkel Cell CarcinomaIn: Journal of Nuclear Medicine (JNM), Jg. 63, 2022, Nr. 3, S. 396 – 398DOI (Open Access)
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Safety and Efficacy of 90Y-FAPI-46 Radioligand Therapy in Patients with Advanced Sarcoma and Other Cancer EntitiesIn: Clinical Cancer Research, Jg. 28, 2022, Nr. 19, S. 4346 – 4353DOI (Open Access)
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Drug and molecular radiotherapy combinations for metastatic castration resistant prostate cancerIn: Nuclear Medicine and Biology, Jg. 96-97, 2021, S. 101 – 111DOI (Open Access)
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Enzalutamide enhances psma expression of psma-low prostate cancerIn: International Journal of Molecular Sciences (IJMS), Jg. 22, 2021, Nr. 14, 7431DOI, Online Volltext (Open Access)
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Imaging Inflammation with Positron Emission TomographyIn: Biomedicines, Jg. 9, 2021, Nr. 2, S. 212DOI, Online Volltext (Open Access)
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Immune-Checkpoint Blockade Enhances ²²⁵Ac-PSMA617 Efficacy in a Mouse Model of Prostate CancerIn: Journal of Nuclear Medicine (JNM), Jg. 62, 2021, Nr. 2, S. 228 – 231DOI (Open Access)
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Mechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate CancerIn: Journal of Nuclear Medicine (JNM), Jg. 62, 2021, Nr. 7, S. 989 – 995DOI (Open Access)
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PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman PrimatesIn: Clinical Cancer Research, Jg. 27, 2021, Nr. 7, S. 2050 – 2060DOI (Open Access)
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Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapyIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Jg. 117, 2020, Nr. 26, S. 15172 – 15181DOI, Online Volltext (Open Access)
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Investigating PSMA-Targeted Radioligand Therapy Efficacy as a Function of Cellular PSMA Levels and Intratumoral PSMA HeterogeneityIn: Clinical Cancer Research, Jg. 26, 2020, Nr. 12, S. 2946 – 2955DOI, Online Volltext (Open Access)
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Targeted alpha therapy in a systemic mouse model of prostate cancer : A feasibility studyIn: Theranostics, Jg. 10, 2020, Nr. 6, S. 2612 – 2620DOI (Open Access)
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Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapyIn: British Journal of Haematology, Jg. 184, 2019, Nr. 3, S. 440 – 443DOI, Online Volltext (Open Access)
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Detection Threshold and Reproducibility of ⁶⁸Ga-PSMA11 PET/CT in a Mouse Model of Prostate CancerIn: Journal of Nuclear Medicine (JNM), Jg. 59, 2018, Nr. 9, S. 1392 – 1397DOI (Open Access)
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Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancerIn: EJNMMI Research, Jg. 8, 2018, Nr. 1, 96DOI (Open Access)
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CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple MyelomaIn: Theranostics, Jg. 7, 2017, Nr. 6, S. 1589 – 1597DOI (Open Access)
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Establishing 177Lu-PSMA-617 Radioligand Therapy in a Syngeneic Model of Murine Prostate CancerIn: Journal of Nuclear Medicine (JNM), Jg. 58, 2017, Nr. 11, S. 1786 – 1792DOI (Open Access)
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Targeting CXCR4 with [68Ga]Pentixafor : A suitable theranostic approach in pleural mesothelioma?In: OncoTarget, Jg. 8, 2017, Nr. 57, S. 96732 – 96737DOI (Open Access)
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[68Ga]Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma - Comparison to [18F]FDG and laboratory valuesIn: Theranostics, Jg. 7, 2017, Nr. 1, S. 205 – 212DOI (Open Access)
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¹¹C-Methionine-PET in Multiple Myeloma : A Combined Study from Two Different InstitutionsIn: Theranostics, Jg. 7, 2017, Nr. 11, S. 2956 – 2964DOI (Open Access)
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First-in-human experience of CXCR4-directed endoradiotherapy with ¹⁷⁷Lu-and ⁹⁰Y-labeled pentixather in advanced-stage multiple myeloma with extensive intra-and extramedullary diseaseIn: Journal of Nuclear Medicine (JNM), Jg. 57, 2016, Nr. 2, S. 248 – 251
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¹¹C-methionine-PET in multiple myeloma : Correlation with clinical parameters and bone marrow involvementIn: Theranostics, Jg. 6, 2016, Nr. 2, S. 254 – 261DOI (Open Access)
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In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myelomaIn: EMBO Molecular Medicine, Jg. 7, 2015, Nr. 4, S. 477 – 487DOI (Open Access)
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¹¹C-Methionine-PET : A novel and sensitive tool for monitoring of early response to treatment in multiple myelomaIn: OncoTarget, Jg. 6, 2015, Nr. 10, S. 8418 – 8429DOI (Open Access)
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¹⁸FDG-PET/CT for prognostic stratification of patients with multiple myeloma relapse after stem cell transplantationIn: OncoTarget, Jg. 5, 2014, Nr. 17, S. 7381 – 7391DOI (Open Access)
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Targeting paraprotein biosynthesis for non-invasive characterization of myeloma biologyIn: PLoS ONE, Jg. 8, 2013, Nr. 12, S. e84840DOI (Open Access)
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Immune modulation by Fas ligand reverse signaling : Lymphocyte proliferation is attenuated by the intracellular Fas ligand domainIn: Blood, Jg. 117, 2011, Nr. 2, S. 519 – 529
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The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cellsIn: Cell Death and Differentiation, Jg. 14, 2007, Nr. 9, S. 1678 – 1687DOI (Open Access)
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A New Chapter in Neoadjuvant Therapy for High-risk Prostate Cancer?In: European Urology. Amsterdam: Elsevier, Jg. 85, 2024, Nr. 3, S. 227 – 228
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Analysing the Tumour Transcriptome of Prostate Cancer to Predict Efficacy of Lu-PSMA Therapy
Annual Congress of the European Association of Nuclear Medicine, 9-13 September 2023 Vienna, Austria,In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 50, 2023, Nr. 1 supplement, S. S180 -
Enhancing PSMA-RLT efficacy with STING agonist in syngeneic models of prostate cancer
Annual Congress of the European Association of Nuclear Medicine, 9-13 September 2023 Vienna, Austria,In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 50, 2023, Nr. 1 supplement, S. S446 -
FAPI, PSMA and FDG PET/CT in patients with advanced metastatic castration-resistant prostate cancer (mCRPC) : a triple tracer comparison
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine October ; 15-19, 2022 Barcelona, Spain,In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 49, 2022, Nr. Supplement 1, S. S118 – S119DOI (Open Access) -
PSMA-directed imaging and therapy of salivary gland tumors : a single-center retrospective study
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022, Barcelona, Spain,In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 49, 2022, Nr. Supplement 1, S. S229DOI (Open Access) -
Safety and efficacy of [90Y]Y-FAPI-46 radioligand therapy in patients with advanced sarcomas and other cancer entities
ESMO Congress 2022, 9 - 13 September 2022, Paris, France,In: Annals of Oncology. Amsterdam: Elsevier, Jg. 33, 2022, Nr. Supplement 7: Abstract Book of the ESMO Congress 2022, 9 - 13 September 2022, S. S1231 – S1232DOI (Open Access) -
Target Expression and FAP-Directed Tumour Imaging in a Large, Single-Centre PET Database of 324 Patients and 21 Tumour Entities
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022, Barcelona, Spain,In: European Journal of Nuclear Medicine and Molecular Imaging. Berlin: Springer, Jg. 49, 2022, Nr. Supplement 1, S. S119 – S120DOI (Open Access)