Welcome to the Sino-German Transregional
Collaborative Research Center TRR60 !


“Mutual interaction of chronic viruses with cells of the immune system: from fundamental research to
immunotherapy and vaccination”


Essen - Wuhan - Bochum - Shanghai

Funded since July 2009

The WHO estimates that almost 500 million people world-wide are chronically infected with HBV, HCV or HIV. The three viruses are transmitted similarly and vaccination against HIV and HCV has not been possible until now. Interestingly, there are substantial differences in the rate of viral persistence after infection with the three viruses. Therefore it is important to compare mechanisms of viral persistence between these viruses. All viruses have to evade the innate and the adaptive immune system to become chronic. In the Transregio, these mechanisms will be intensively studied in cell culture, animal models, and patients. These studies should provide new clues on how to treat or vaccinate against chronic viral infections.





September 2015 Interactive app for understanding infectious diseases

The TRR60 has contibuted to the interactive tablet-app launched and offered by DFG free of charge: 

MenschMikrobe – Die interaktive App zur Infektionsforschung
Eine faszinierende Tour durch die Welt der Mikroorganismen – für Experten, Laien und Schüler
more info: www.dfg.de/menschmikrobe or see the info-flyer