Personensuche

Personensuche

Bitte geben Sie den Namen der gesuchten Person ein.

Es wurde 1 Person gefunden.

Prof. Dr. med. Alexander Röth

Funktionen

  • , Klinik für Hämatologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Nishimori, Hisakazu; Nakazawa, Hideyuki; Tamura, Shinobu; Uchida, Toshiki; Usuki, Kensuke; Szamosi, Johan; De Latour, Régis Peffault; Röth, Alexander; Panse, Jens
    Efficacy, Safety, and Quality of Life of Pegcetacoplan in Japanese Patients with Paroxysmal Nocturnal Hemoglobinuria Treated within the Phase 3 PEGASUS Trial
    In: Acta Haematologica Jg. 148 (2025) Nr. 1, S. 22 - 35
    Online Volltext: dx.doi.org/ (Open Access)
  • Cella, David; Hill, Quentin A.; Karaouni, Alia; Joly, Florence; Sourdille, Timothee; Shafer, Frank; Wardęcki, Marek; Kosinski, Mark; Röth, Alexander
    FACIT-Fatigue scale in patients with cold agglutinin disease : Psychometric validation and estimation of clinically meaningful change
    In: Frontiers in Hematology Jg. 4 (2025) 1490130
    Online Volltext: dx.doi.org/ (Open Access)
  • Cosson, Valérie; Fu, Rong; Kulasekararaj, Austin; Nishimura, Jun-Ichi; Panse, Jens; Röth, Alexander; Scheinberg, Phillip; Tong, Hongyan; Yoon, Sung-Soo; Beveridge, Leigh; Gotanda, Keisuke; Jaminion, Félix; Henrich, Andrea; Lundberg, Pontus; Shi, Dayu; Sreckovic, Sasha; Zhang, Yuchen; Zhang, Zilu; Benkali, Khaled; Buatois, Simon
    Pharmacokinetic characterization and exposure–response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria
    In: British Journal of Clinical Pharmacology (BJCP) (2025) in press
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin; Brodsky, Robert; Schrezenmeier, Hubert; Griffin, Morag; Röth, Alexander; Piatek, Caroline; Ogawa, Masayo; Yu, Ji; Patel, Ami S.; Patel, Yogesh; Notaro, Rosario; Usuki, Kensuke; Kulagin, Alexander; Gualandro, Sandra; Füreder, Wolfgang; Peffault de Latour, Regis; Szer, Jeff; Lee, Jong Wook
    Ravulizumab demonstrates long-term efficacy, safety and favorable patient survival in patients with paroxysmal nocturnal hemoglobinuria
    In: Annals of Hematology (2025) in press
    Online Volltext: dx.doi.org/ (Open Access)
  • Fattizzo, Bruno; Röth, Alexander; Broome, Catherine M.; Khan, Umer; Wardęcki, Marek; Cordoba, Matias; Barcellini, Wilma
    COVID-19 vaccine safety and immunogenicity in patients with cold agglutinin disease receiving concomitant sutimlimab
    In: American Journal of Hematology Jg. 99 (2024) Nr. 4, S. 789 - 791
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Anderson Tvedt, Tor Henrik; Miyakawa, Yoshitaka; Kuter, David J.; Su, Jun; Jiang, Xiaoyu; Hobbs, William; Morales, Jaime; Shafer, Frank; Weitz, Ilene C.
    Correction to: Sutimlimab improves quality of life in patients with cold agglutinin disease : Results of patient-reported outcomes from the CARDINAL study
    In: Annals of Hematology Jg. 103 (2024) Nr. 5, S. 1803
    Online Volltext: dx.doi.org/ (Open Access)
  • Poppenborg, Friederike; Röth, Alexander; Yamamoto, Raina; Reinhardt, Hans Christian; Alashkar, Ferras
    Crizanlizumab in adult patients with sickle cell disease: : a retrospective German analysis
    In: Frontiers in Hematology Jg. 3 (2024) 1374181
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Kulasekararaj, Austin G.; Scheinberg, Phillip; Nishimura, Jun-ichi
    Crovalimab in the paroxysmal nocturnal hemoglobinuria treatment landscape
    In: Immunotherapy Jg. 16 (2024) Nr. 20-22, S. 1185 - 1196
    Online Volltext: dx.doi.org/ (Open Access)
  • Dingli, David; De Castro III, Carlos; Koprivnikar, Jamie; Kulasekararaj, Austin; Maciejewski, Jaroslaw; Mulherin, Brian; Panse, Jens; Pullarkat, Vinod; Röth, Alexander; Shammo, Jamile; Terriou, Louis; Weitz, Ilene; Yermilov, Irina; Gibbs, Sarah; Broder, Michael; Beenhouwer, David; Kuter, David
    Expert consensus on the management of pharmacodynamic breakthrough-hemolysis in treated paroxysmal nocturnal hemoglobinuria
    In: Hematology Jg. 29 (2024) Nr. 1, 2329030
    Online Volltext: dx.doi.org/ (Open Access)
  • Kuter, David J.; Piatek, Caroline; Röth, Alexander; Siddiqui, Asif; Numerof, Robert P.; Dummer, Wolfgang
    Fostamatinib for warm antibody autoimmune hemolytic anemia : Phase 3, randomized, double-blind, placebo-controlled, global study (FORWARD)
    In: American Journal of Hematology Jg. 99 (2024) Nr. 1, S. 79 - 87
    Online Volltext: dx.doi.org/ (Open Access)
  • Schorb, Elisabeth; Isbell, Lisa Kristina; Kerkhoff, Andrea; Mathas, Stephan; Braulke, Friederike; Egerer, Gerlinde; Röth, Alexander; Schliffke, Simon; Borchmann, Peter; Brunnberg, Uta; Kroschinsky, Frank; Möhle, Robert; Rank, Andreas; Wellnitz, Dominique; Kasenda, Benjamin; Pospiech, Lisa; Wendler, Julia; Scherer, Florian; Deckert, Martina; Henkes, Elina; von Gottberg, Philipp; Gmehlin, Dennis; Backenstraß, Matthias; Jensch, Antje; Burger-Martin, Elvira; Grishina, Olga; Fricker, Heidi; Malenica, Natalie; Orbán, András; Duyster, Justus; Ihorst, Gabriele; Finke, Juergen; Illerhaus, Gerald
    High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA) : A single-arm, phase 2 trial
    In: The Lancet Haematology Jg. 11 (2024) Nr. 3, S. e196 - e205
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Jayawardene, Deepthi; Srivastava, Shruti; Wardęcki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.; D’Sa, Shirley
    Long-term efficacy and safety of continued complement C1s inhibition with sutimlimab in cold agglutinin disease : CADENZA study Part B
    In: eClinicalMedicine Jg. 74 (2024) 102733
    Online Volltext: dx.doi.org/ (Open Access)
  • Peffault de Latour, Régis; Röth, Alexander; Kulasekararaj, Austin G.; Han, Bing; Scheinberg, Phillip; Maciejewski, Jaroslaw P.; Ueda, Yasutaka; de Castro, Carlos M.; Di Bona, Eros; Fu, Rong; Zhang, Li; Griffin, Morag; Langemeijer, Saskia M.C.; Panse, Jens; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor A.Q.; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Chew, Lee Ping; Gaya, Anna; Huang, Wei-Han; Jang, Jun Ho; Kitawaki, Toshio; Kutlar, Abdullah; Notaro, Rosario; Pullarkat, Vinod; Schubert, Jörg; Terriou, Louis; Uchiyama, Michihiro; Lee, Lily Wong Lee; Yap, Eng-Soo; de Fontbrune, Flore Sicre; Marano, Luana; Alashkar, Ferras; Gandhi, Shreyans; Trikha, Roochi; Yang, Chen; Liu, Hui; Kelly, Richard J.; Höchsmann, Britta; Kerloeguen, Cécile; Banerjee, Partha; Levitch, Rafael; Kumar, Rakesh; Wang, Zhixin; Thorburn, Christine; Maitra, Samopriyo; Li, Shujie; Verles, Aurelie; Dahlke, Marion; Risitano, Antonio M.
    Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria
    In: The New England Journal of Medicine Jg. 390 (2024) Nr. 11, S. 994 - 1008
    Online Volltext: dx.doi.org/ (Open Access)
  • Wilson, Koo; Rich, Carly; Hakimi, Zalmai; Horneff, Regina; Fishman, Jesse; Mellor, Jennifer; Earl, Lucy; Taylor, Yasmin; Simons, Alice; Conyers, Joe; Mulherin, Brian; Majerus, Elaine; Röth, Alexander
    Pegcetacoplan in paroxysmal nocturnal haemoglobinuria : Its use, its clinical effectiveness, and its influence on health-related quality of life and productivity
    In: European Journal of Haematology Jg. 112 (2024) Nr. 4, S. 516 - 529
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; He, Guangsheng; Tong, Hongyan; Lin, Zenghua; Wang, Xiaoqin; Chai-Adisaksopha, Chatree; Lee, Je-Hwan; Brodsky, Andres; Hantaweepant, Chattree; Dumagay, Teresita E.; Demichelis-Gómez, Roberta; Rojnuckarin, Ponlapat; Sun, Jing; Höglund, Martin; Jang, Jun Ho; Gaya, Anna; Silva, Fernando; Obara, Naoshi; Kelly, Richard J.; Beveridge, Leigh; Buatois, Simon; Chebon, Sammy; Gentile, Brittany; Lundberg, Pontus; Sreckovic, Sasha; Nishimura, Jun-ichi; Risitano, Antonio; Han, Bing
    Phase 3 randomized COMMODORE 2 trial : Crovalimab versus eculizumab in patients with paroxysmal nocturnal hemoglobinuria naive to complement inhibition
    In: American Journal of Hematology Jg. 99 (2024) Nr. 9, S. 1768 - 1777
    Online Volltext: dx.doi.org/ (Open Access)
  • de Latour, Régis Peffault; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; Castro, Carlos de; Nishimori, Hisakazu; Al-Adhami, Mohammed; Deschatelets, Pascal; Francois, Cedric; Risitano, Antonio; Hillmen, Peter
    Plain language summary : treatment of paroxysmal nocturnal hemoglobinuria with pegcetacoplan for 48 weeks (PEGASUS study)
    In: Future Rare Diseases Jg. 4 (2024) Nr. 1, 2340267
    Online Volltext: dx.doi.org/ (Open Access)
  • Patriquin, Christopher J.; Bogdanovic, Andrija; Griffin, Morag; Kelly, Richard J.; Maciejewski, Jaroslaw P.; Mulherin, Brian; Peffault de Latour, Régis; Röth, Alexander; Selvaratnam, Veena; Szer, Jeffrey; Al-Adhami, Mohammed; Horneff, Regina; Tan, Lisa; Yeh, Michael; Panse, Jens
    Safety and Efficacy of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria over 48 Weeks : 307 Open-Label Extension Study
    In: Advances in Therapy Jg. 41 (2024) Nr. 5, S. 2050 - 2069
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Fu, Rong; He, Guangsheng; Alzahrani, Hazzaa; Chou, Sheng-Chieh; Hicheri, Yosr; Kaźmierczak, Maciej; Recova, Viviane Lacorte; Uchiyama, Michihiro; Vladareanu, Ana-Maria; Beveridge, Leigh; Buatois, Simon; Buri, Muriel; Compagno, Nicolo; Shi, Dayu; Balachandran, Nadiesh; Sreckovic, Sasha; Scheinberg, Phillip
    Safety of Crovalimab Versus Eculizumab in Patients With Paroxysmal Nocturnal Haemoglobinuria (PNH) : Pooled Results From the Phase 3 COMMODORE Studies
    In: European Journal of Haematology Jg. 114 (2024) Nr. 2, S. 373 - 382
    Online Volltext: dx.doi.org/ (Open Access)
  • D'Sa, Shirley; Vos, Josephine M. I.; Barcellini, Wilma; Wardęcki, Marek; Perrin, Laurent; Barker, Graham; Zilberstein, Moshe; Storek, Michael; Chow, Timothy; Röth, Alexander
    Safety, tolerability, and activity of the active C1s antibody riliprubart in cold agglutinin disease : A phase 1b study
    In: Blood Jg. 143 (2024) Nr. 8, S. 713 - 720
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Anderson Tvedt, Tor Henrik; Yamaguchi, Masaki; Murakhovskaya, Irina; Lee, Michelle; Shafer, Frank; Wardęcki, Marek; Jayawardene, Deepthi; Yoo, Ronnie; Msihid, Jerome; Weitz, Ilene C.
    Sustained improvements in patient-reported outcomes after long-term sutimlimab in patients with cold agglutinin disease : results from the CADENZA study open-label extension
    In: eClinicalMedicine Jg. 74 (2024) 102732
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin G.; Kuter, David J.; Griffin, Morag; Weitz, Ilene C.; Röth, Alexander
    Biomarkers and laboratory assessments for monitoring the treatment of patients with paroxysmal nocturnal hemoglobinuria : Differences between terminal and proximal complement inhibition
    In: Blood Reviews Jg. 59 (2023) 101041
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Ichikawa, Satoshi; Ito, Yoshikazu; Kim, Jin Seok; Nagy, Zsolt; Obara, Naoshi; Panse, Jens; Schrezenmeier, Hubert; Sica, Simona; Soret, Juliette; Usuki, Kensuke; Yoon, Sung-Soo; Balachandran, Nadiesh; Buri, Muriel; Lundberg, Pontus; Patel, Himika; Shinomiya, Kenji; Sostelly, Alexandre; Nishimura, Jun-ichi
    Crovalimab treatment in patients with paroxysmal nocturnal haemoglobinuria : Long-term results from the phase I/II COMPOSER trial
    In: European Journal of Haematology Jg. 111 (2023) Nr. 2, S. 300 - 310
    Online Volltext: dx.doi.org/ (Open Access)
  • Terriou, Louis; Lee, Jong Wook; Forsyth, Cecily; Griffin, Morag; Szer, Jeff; Röth, Alexander; Gustovic, Philippe; Metzger, Jesse; Patel, Ami S.; Patriquin, Christopher J.
    Long-term effectiveness of eculizumab: Data from the International PNH Registry
    In: European Journal of Haematology Jg. 111 (2023) Nr. 5, S. 796 - 804
    Online Volltext: dx.doi.org/ (Open Access)
  • Versmold, Katharina; Alashkar, Ferras; Raiser, Carina; Ofori-Asenso, Richard; Xu, Tao; Liu, Yutong; Katz, Pablo; Shang, Aijing; Röth, Alexander
    Long-term outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab in a real-world setting
    In: European Journal of Haematology Jg. 111 (2023) Nr. 1, S. 84 - 95
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Tvedt, Tor Henrik Anderson; Miyakawa, Yoshitaka; D’Sa, Shirley; Cella, David; Bozzi, Sylvie; Jayawardene, Deepthi; Yoo, Ronnie; Shafer, Frank; Wardecki, Marek; Weitz, Ilene C.; D’Sa, Shirley
    Long-term sutimlimab improves quality of life for patients with cold agglutinin disease : CARDINAL 2-year follow-up
    In: Blood Advances Jg. 7 (2023) Nr. 19, S. 5890 - 5897
    Online Volltext: dx.doi.org/ (Open Access)
  • Nishimura, Jun-ichi; Soubret, Antoine; Arase, Noriko; Buatois, Simon; Hotta, Masaki; Charoin, Jean-Eric; Ito, Yoshikazu; Sreckovic, Sasha; Takamori, Hiroyuki; Bucher, Christoph; Ueda, Yasutaka; Hernández-Sánchez, Jules; Gotanda, Keisuke; Jordan, Gregor; Shinomiya, Kenji; Ramos, Julia; Kim, Jin Seok; Panse, Jens; de Latour, Régis Peffault; Röth, Alexander; Morii, Eiichi; Schrezenmeier, Hubert; Isaka, Yoshitaka; Sica, Simona; Kanakura, Yuzuru; Yoon, Sung-Soo; Kinoshita, Taroh; Paz-Priel, Ido; Sostelly, Alexandre
    Mitigating Drug–Target–Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors
    In: Clinical Pharmacology & Therapeutics Jg. 113 (2023) Nr. 4, S. 904 - 915
    Online Volltext: dx.doi.org/ (Open Access)
  • Griffin, Morag; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Hillmen, Peter; Kiladjian, Jean-Jacques; Castro, Carlos De; Nishimori, Hisakazu; Tan, Lisa; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Ajayi, Temitayo; Risitano, Antonio; De La Tour, Régis Peffault
    Plain language summary of PEGASUS, a study comparing pegcetacoplan with eculizumab for 16 weeks in people with paroxysmal nocturnal hemoglobinuria
    In: Future Rare Diseases Jg. 3 (2023) Nr. 3, FRD42
    Online Volltext: dx.doi.org/ (Open Access)
  • Höchsmann, Britta; Peffault de Latour, Regis; Hill, Anita; Röth, Alexander; Devos, Timothy; Patriquin, Christopher J.; Chou, Wen-Chien; Jain, Deepak; Zu, Ke; Wu, Chuntao; Lee, Jong Wook
    Risk factors for thromboembolic events in patients with paroxysmal nocturnal hemoglobinuria (PNH) : a nested case–control study in the International PNH Registry
    In: Annals of Hematology Jg. 102 (2023) Nr. 11, S. 2979 - 2988
    Online Volltext: dx.doi.org/ (Open Access)
  • Broome, Catherine M.; Röth, Alexander; Kuter, David J.; Scully, Marie; Smith, Roy; Wang, Jennifer; Reuter, Caroline; Hobbs, William; Daak, Ahmed
    Safety and efficacy of classical complement pathway inhibition with sutimlimab in chronic immune thrombocytopenia
    In: Blood Advances Jg. 7 (2023) Nr. 6, S. 987 - 996
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Barcellini, Wilma; D'Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M.; Michel, Marc; Kuter, David J.; Jilma, Bernd; Tvedt, Tor Henrik Anderson; Weitz, Ilene C.; Yoo, Ronnie; Jayawardene, Deepthi; Vagge, Deepthi S.; Kralova, Katarina; Shafer, Frank; Wardȩcki, Marek; Lee, Michelle; Berentsen, Sigbjørn
    Sustained inhibition of complement C1s with sutimlimab over 2 years in patients with cold agglutinin disease
    In: American Journal of Hematology Jg. 98 (2023) Nr. 8, S. 1246 - 1253
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Tvedt, Tor Henrik Anderson; Yamaguchi, Masaki; Lee, Michelle; Shafer, Frank; Wardęcki, Marek; Jiang, Xiaoyu; Patel, Parija; Joly, Florence; Weitz, Ilene C.
    Sutimlimab provides clinically meaningful improvements in patient-reported outcomes in patients with cold agglutinin disease : Results from the randomised, placebo-controlled, Phase 3 CADENZA study
    In: European Journal of Haematology Jg. 110 (2023) Nr. 3, S. 280 - 288
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Bertram, Stefanie; Schroeder, Thomas; Haverkamp, Thomas; Voigt, Sebastian; Holtkamp, Caroline; Klump, Hannes; Wörmann, Bernhard; Reinhardt, Hans Christian; Alashkar, Ferras
    Acquired aplastic anemia following SARS-CoV-2 vaccination
    In: European Journal of Haematology Jg. 109 (2022) Nr. 2, S. 186 - 194
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Barcellini, Wilma; D'Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M.; Michel, Marc; Kuter, David J.; Jilma, Bernd; Tvedt, Tor Henrik Anderson; Weitz, Ilene C.; Patel, Parija; Jiang, Xiaoyu; Reuter, Caroline; Su, Jun; Shafer, Frank; Lee, Michelle; Berentsen, Sigbjørn; D’Sa, Shirley; Berentsen, Sigbjorn
    Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease : CARDINAL study 1-year interim follow-up results
    In: Haematologica / The Hematology Journal Jg. 107 (2022) Nr. 7, S. 1698 - 1702
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Fryzek, Jon; Jiang, Xiaohui; Reichert, Heidi; Patel, Parija; Su, Jun; Morales Arias, Jaime; Broome, Catherine M.
    Complement-mediated hemolysis persists year round in patients with cold agglutinin disease
    In: Transfusion Jg. 62 (2022) Nr. 1, S. 51 - 59
    Online Volltext: dx.doi.org/ (Open Access)
  • Nishimura, Jun-ichi; Usuki, Kensuke; Ramos, Julia; Ichikawa, Satoshi; Buri, Muriel; Kiialainen, Anna; Sostelly, Alexandre; Peffault de Latour, Régis; Paz-Priel, Ido; Röth, Alexander
    Crovalimab for treatment of patients with paroxysmal nocturnal haemoglobinuria and complement C5 polymorphism : Subanalysis of the phase 1/2 COMPOSER study
    In: British Journal of Haematology (2022)
    Online Volltext: dx.doi.org/ (Open Access)
  • Ferreri, Andrés J. M.; Cwynarski, Kate; Pulczynski, Elisa; Fox, Christopher P.; Schorb, Elisabeth; Celico, Claudia; Falautano, Monica; Nonis, Alessandro; La Rosée, Paul; Binder, Mascia; Fabbri, Alberto; Ilariucci, Fiorella; Krampera, Mauro; Röth, Alexander; Hemmaway, Claire; Johnson, Peter W.; Linton, Kim M.; Pukrop, Tobias; Gørløv, Jettes Sønderskov; Balzarotti, Monica; Hess, Georg; Keller, Ulrich; Stilgenbauer, Stephan; Panse, Jense; Tucci, Alessandra; Orsucci, Lorella; Pisani, Francesco; Zanni, Manuela; Krause, Stefan W.; Schmoll, Hans J.; Hertenstein, Bernd; Rummel, Mathias; Smith, Jeffery; Thurner, Lorenz; Cabras, Giuseppina; Pennese, Elsa; Ponzoni, Maurilio; Deckert, Martina; Politi, Letterio S.; Finke, Jurgen; Ferranti, Antonella; Cozens, Kelly; Burger, Elvira; Ielmini, Nicoletta; Cavalli, Franco; Zucca, Emanuele; Illerhaus, Gerald; IELSG32 study investigators
    Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma : 7-year results of the IELSG32 randomized trial
    In: Leukemia Jg. 36 (2022) Nr. 7, S. 1870 - 1878
    Online Volltext: dx.doi.org/
  • Alashkar, Ferras; Klump, Hannes; Lange, Cara Paulina; Proske, Pia; Schüssler, Maximilian; Yamamoto, Raina; Carpinteiro, Alexander; Berliner, Christoph Alexander; Schlosser, Thomas Wilfried; Röth, Alexander; Reinhardt, Hans Christian
    Luspatercept, a two‐edged sword in beta‐thalassemia‐associated paravertebral extramedullary hematopoietic masses (EHMs)
    In: European Journal of Haematology Jg. 109 (2022) Nr. 6, S. 664 - 671
    Online Volltext: dx.doi.org/ (Open Access)
  • de Latour, Régis Peffault; Szer, Jeff; Weitz, Ilene C; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; de Castro, Carlos M; Nishimori, Hisakazu; Ajayi, Temitayo; Al-Adhami, Mohammed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio M; Hillmen, Peter
    Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS) : 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial
    In: The Lancet Haematology Jg. 9 (2022) Nr. 9, S. e648 - e659
    Online Volltext: dx.doi.org/
  • Aramayo-Singelmann, Carmen; Halimeh, Susan; Proske, Pia; Vignalingarajah, Abinuja; Cario, Holger; Christensen, Morten O.; Yamamoto, Raina; Röth, Alexander; Reinhardt, Dirk; Reinhardt, Hans Christian; Alashkar, Ferras
    Screening and diagnosis of hemoglobinopathies in Germany: Current state and future perspectives
    In: Scientific Reports Jg. 12 (2022) Nr. 1, 9762
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Tvedt, Tor Henrik Anderson; Miyakawa, Yoshitaka; Kuter, David J.; Su, Jun; Jiang, Xiaoyu; Hobbs, William; Arias, Jaime Morales; Shafer, Frank; Weitz, Ilene C.
    Sutimlimab improves quality of life in patients with cold agglutinin disease : results of patient-reported outcomes from the CARDINAL study
    In: Annals of Hematology Jg. 101 (2022) Nr. 10, S. 2169 - 2177
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Storek, Michael; Wong, Nancy; Patel, Parija; Jiang, Xiaoyu; Vagge, Deepthi S.; Wardęcki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.
    Sutimlimab in patients with cold agglutinin disease : results of the randomized placebo-controlled phase 3 CADENZA trial
    In: Blood Jg. 140 (2022) Nr. 9, S. 980 - 991
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, Antonio M.; Röth, Alexander; Soret, Juliette; Frieri, Camilla; de Fontbrune, Flore Sicre; Marano, Luana; Alashkar, Ferras; Benajiba, Lina; Marotta, Serena; Rozenberg, Izabela; Milojevic, Julie; End, Peter; Nidamarthy, Prasanna K.; Junge, Guido; Peffault de Latour, Régis
    Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis : An open-label, single-arm, phase 2, proof-of-concept trial
    In: The Lancet Haematology Jg. 8 (2021) Nr. 5, S. e344 - e354
    Online Volltext: dx.doi.org/
  • Brodsky, Robert A.; De Latour, Régis Peffault; Rottinghaus, Scott T.; Röth, Alexander; Risitano, Antonio M.; Weitz, Ilene C.; Hillmen, Peter; MacIejewski, Jaroslaw P.; Szer, Jeff; Lee, Jong Wook; Kulasekararaj, Austin G.; Volles, Lori; Damokosh, Andrew I.; Ortiz, Stephan; Shafner, Lori; Liu, Peng; Hill, Anita; Schrezenmeier, Hubert
    Characterization of breakthrough hemolysis events observed in the phase III randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria
    In: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. 1, S. 230 - 237
    Online Volltext: dx.doi.org/ (Open Access)
  • Leibundgut, Elisabeth Oppliger; Haubitz, Monika; Burington, Bart; Ottmann, Oliver G.; Spitzer, Gary; Odenike, Olatoyosi; McDevitt, Michael A.; Röth, Alexander; Snyder, David S.; Baerlocher, Gabriela M.
    Dynamics of mutations in patients with essential thrombocythemia treated with imetelstat
    In: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. 9, S. 2397 - 2404
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin G.; Hill, Anita; Langemeijer, Saskia; Wells, Richard; González Fernández, F. Ataúlfo; Gaya, Anna; Ojeda Gutierrez, Emilio; Piatek, Caroline I.; Mitchell, Lindsay; Usuki, Kensuke; Bosi, Alberto; Brodsky, Robert A.; Ogawa, Masayo; Yu, Ji; Ortiz, Stephan; Röth, Alexander; Lee, Jong Wook; Peffault de Latour, Régis
    One-year outcomes from a phase 3 randomized trial of ravulizumab in adults with paroxysmal nocturnal hemoglobinuria who received prior eculizumab
    In: European Journal of Haematology Jg. 106 (2021) Nr. 3, S. 389 - 397
    Online Volltext: dx.doi.org/ (Open Access)
  • Hillmen, Peter; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; de Castro, Carlos; Nishimori, Hisakazu; Tan, Lisa; Hamdani, Mohamed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Ajayi, Temitayo; Risitano, Antonio; de la Tour, Régis Peffault
    Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria
    In: The New England Journal of Medicine Jg. 384 (2021) Nr. 11, S. 1028 - 1037
    Online Volltext: dx.doi.org/ (Open Access)
  • Proske, Pia; Distelmaier, Laura; Aramayo-Singelmann, Carmen; Koliastas, Nikolaos; Iannaccone, Antonella; Papathanasiou, Maria; Temme, Christian; Klump, Hannes; Lenz, Veronika; Koldehoff, Michael; Carpinteiro, Alexander; Reinhardt, Hans Christian; Köninger, Angela; Röth, Alexander; Yamamoto, Raina; Dührsen, Ulrich; Alashkar, Ferras
    Pregnancies and neonatal outcomes in patients with sickle cell disease (SCD) : Still a (high-)risk constellation?
    In: Journal of Personalized Medicine Jg. 11 (2021) Nr. 9, 870
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Barcellini, Wilma; D’Sa, Shirley; Miyakawa, Yoshitaka; Broome, Catherine M.; Michel, Marc; Kuter, David J.; Jilma, Bernd; Tvedt, Tor H.A.; Frübis, Joachim; Jiang, Xiaoyu; Lin, Stella; Reuter, Caroline; Morales-Arias, Jaime; Hobbs, William; Berentsen, Sigbjørn
    Sutimlimab in cold agglutinin disease
    In: The New England Journal of Medicine Jg. 384 (2021) Nr. 14, S. 1323 - 1334
    Online Volltext: dx.doi.org/ (Open Access)
  • Karow, Axel; Haubitz, Monika; Oppliger Leibundgut, Elisabeth; Helsen, Ingrid; Preising, Nicole; Steiner, Daniela; Dantonello, Tobias M.; Ammann, Roland A.; Rössler, Jochen; Kartal‐Kaess, Mutlu; Röth, Alexander; Baerlocher, Gabriela M.
    Targeting telomere biology in acute lymphoblastic leukemia
    In: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 13, 6653
    Online Volltext: dx.doi.org/ (Open Access)
  • Schrezenmeier, Hubert; Röth, Alexander; Araten, David J.; Kanakura, Yuzuru; Larratt, Loree; Shammo, Jamile M.; Wilson, Amanda; Shayan, Gilda; Maciejewski, Jaroslaw P.
    Baseline clinical characteristics and disease burden in patients with paroxysmal nocturnal hemoglobinuria (PNH) : updated analysis from the International PNH Registry
    In: Annals of Hematology Jg. 99 (2020) S. 1505 - 1514
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Araten, David J.; Larratt, Loree; Kulasekararaj, Austin G.; Maciejewski, Jaroslaw P.; Wilson, Amanda; Gustovic, Philippe; Kanakura, Yuzuru
    Beneficial effects of eculizumab regardless of prior transfusions or bone marrow disease : Results of the International Paroxysmal Nocturnal Hemoglobinuria Registry
    In: European Journal of Haematology Jg. 105 (2020) Nr. 5, S. 561 - 570
    Online Volltext: dx.doi.org/ (Open Access)
  • Jäger, Ulrich; Barcellini, Wilma; Broome, Catherine M.; Gertz, Morie A.; Hill, Anita; Hill, Quentin A.; Jilma, Bernd; Kuter, David J.; Michel, Marc; Montillo, Marco; Röth, Alexander; Zeerleder, Sacha S.; Berentsen, Sigbjørn
    Diagnosis and treatment of autoimmune hemolytic anemia in adults : Recommendations from the First International Consensus Meeting
    In: Blood Reviews Jg. 41 (2020) S. 100648
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander
    Do temperature and time matter in cold agglutinin disease?
    In: Blood Jg. 136 (2020) Nr. 4, S. 380 - 381
    Online Volltext: dx.doi.org/ (Open Access)
  • Tichelli, André; De Latour, Régis Peffault; Passweg, Jakob; Knol-Bout, Cora; Socié, Gérard; Marsh, Judith; Schrezenmeier, Hubert; Höchsmann, Britta; Bacigalupo, Andrea; Samarasinghe, Sujith; Rovó, Alicia; Kulasekararaj, Austin; Röth, Alexander; Eikema, Dirk-Jan; Bosman, Paul; Bader, Peter; Risitano, Antonio; Dufour, Carlo
    Long-term outcome of a randomized controlled study in patients with newly diagnosed severe aplastic anemia treated with antithymocyte globulin and cyclosporine, with or without granulocyte colony-stimulating factor : A Severe Aplastic Anemia Working Party Trial from the European Group of Blood and Marrow Transplantation
    In: Haematologica / The Hematology Journal Jg. 105 (2020) Nr. 5, S. 1223 - 1231
    Online Volltext: dx.doi.org/ (Open Access)
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Röth, Alexander; Möllmann, Michael; Reinhardt, Hans Christian; Dührsen, Ulrich; Dürig, Jan
    Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemia
    In: European Journal of Haematology Jg. 105 (2020) Nr. 6, S. 786 - 796
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Rottinghaus, Scott; Vance, Colin; Herich-Terhürne, Dörte; Dührsen, Ulrich; Assert, Roland; Röth, Alexander
    No evidence for hypogammaglobulinemia in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with ravulizumab
    In: PLoS ONE Jg. 15 (2020) Nr. 3,
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Peipert, John Devin; Kulasekararaj, Austin G.; Gaya, Anna; Langemeijer, Saskia M C; Yount, Susan; Gonzalez-Fernandez, F Ataulfo; Ojeda Gutierrez, Emilio; Martens, Christa; Sparling, Amy; Webster, Kimberly A.; Cella, David; Tomazos, Ioannis; Ogawa, Masayo; Piatek, Caroline I.; Wells, Richard; Sicre de Fontbrune, Flore; Röth, Alexander; Mitchell, Lindsay; Hill, Anita; Kaiser, Karen
    Patient preferences and quality of life implications of ravulizumab (every 8 weeks) and eculizumab (every 2 weeks) for the treatment of paroxysmal nocturnal hemoglobinuria
    In: PLoS ONE Jg. 15 (2020) Nr. 9, S. e0237497
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Saner, Fuat; Vance, Colin; Schmücker, Ute; Herich-Terhürne, Dörte; Dührsen, Ulrich; Köninger, Angela; Röth, Alexander
    Pregnancy in Classical Paroxysmal Nocturnal Hemoglobinuria and Aplastic Anemia–Paroxysmal Nocturnal Hemoglobinuria : A High-Risk Constellation
    In: Frontiers in Medicine Jg. 7 (2020) S. 543372
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Nishimura, Jun-Ichi; Nagy, Zsolt; Gaàl-Weisinger, Julia; Panse, Jens; Yoon, Sung-Soo; Egyed, Miklos; Ichikawa, Satoshi; Ito, Yoshikazu; Kim, Jin Seok; Ninomiya, Haruhiko; Schrezenmeier, Hubert; Sica, Simona; Usuki, Kensuke; Sicre de Fontbrune, Flore; Soret, Juliette; Sostelly, Alexandre; Higginson, James; Dieckmann, Andreas; Gentile, Brittany; Anzures-Cabrera, Judith; Shinomiya, Kenji; Jordan, Gregor; Biedzka-Sarek, Marta; Klughammer, Barbara; Jahreis, Angelika; Bucher, Christoph; Peffault de Latour, Régis
    The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria
    In: Blood Jg. 135 (2020) Nr. 12, S. 912 - 920
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Herbstreit, Frank; Carpinteiro, Alexander; Baum, Julia; Tzalavras, Asterios; Aramayo-Singelmann, Carmen; Vance, Colin; Lenz, Veronika; Gulbins, Erich; Reinhardt, Dirk; Beelen, Dietrich; Dührsen, Ulrich; Röth, Alexander; Koldehoff, Michael; Liebregts, Tobias
    Veno-Venous Extracorporeal Membrane Oxygenation in Adult Patients with Sickle Cell Disease and Acute Chest Syndrome : a Single-Center Experience
    In: Hemoglobin Jg. 44 (2020) Nr. 2, S. 71 - 77
    Online Volltext: dx.doi.org/
  • Berentsen, Sigbjørn; Röth, Alexander; Randen, Ulla; Jilma, Bernd; Tjønnfjord, Geir E
    Cold agglutinin disease : current challenges and future prospects
    In: Journal of Blood Medicine Jg. 10 (2019) S. 93 - 103
    Online Volltext: dx.doi.org/ (Open Access)
  • Niedeggen, Cathrin; Singer, Susanne; Groth, Martha; Petermann-Meyer, Andrea; Röth, Alexander; Schrezenmeier, Hubert; Höchsmann, Britta; Brümmendorf, Tim H.; Panse, Jens
    Design and development of a disease-specific quality of life tool for patients with aplastic anaemia and/or paroxysmal nocturnal haemoglobinuria (QLQ-AA/PNH)—a report on phase III
    In: Annals of Hematology Jg. 98 (2019) Nr. 7, S. 1547 - 1559
    Online Volltext: dx.doi.org/ (Open Access)
  • Lee, Jong Wook; Peffault de Latour, Régis; Brodsky, Robert A.; Jang, Jun Ho; Hill, Anita; Röth, Alexander; Schrezenmeier, Hubert; Wilson, Amanda; Marantz, Jing L.; Maciejewski, Jaroslaw P.
    Effectiveness of eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) with or without aplastic anemia in the International PNH Registry
    In: American Journal of Hematology Jg. 94 (2019) Nr. 1, S. E37 - E41
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Oelmüller, Maren; Herich-Terhürne, Dörte; Turki, Amin T.; Schmitz, Christine; Vance, Colin; Dührsen, Ulrich; Röth, Alexander
    Immunosuppressive therapy (IST) in adult patients with acquired aplastic anemia (AA) : A single-center experience over the past 15 years
    In: European Journal of Haematology Jg. 103 (2019) Nr. 1, S. 18 - 25
    Online Volltext: dx.doi.org/
  • Bylsma, Lauren C.; Ording, Anne Gulbech; Rosenthal, Adam; Öztürk, Buket; Fryzek, Jon P.; Arias, Jaime Morales; Röth, Alexander; Berentsen, Sigbjørn
    Occurrence, thromboembolic risk, and mortality in Danish patients with cold agglutinin disease
    In: Blood Advances Jg. 3 (2019) Nr. 20, S. 2980 - 2985
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin G.; Hill, Anita; Rottinghaus, Scott T.; Langemeijer, Saskia; Wells, Richard; Gonzalez-Fernandez, F. Ataulfo; Gaya, Anna; Lee, Jong Wook; Ojeda Gutierrez, Emilio; Piatek, Caroline I.; Szer, Jeff; Risitano, Antonio; Nakao, Shinji; Bachman, Eric; Shafner, Lori; Damokosh, Andrew I.; Ortiz, Stephan; Röth, Alexander; Peffault de Latour, Regis
    Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor-experienced adult patients with PNH : the 302 study
    In: Blood Jg. 133 (2019) Nr. 6, S. 540 - 549
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Alashkar, Ferras; Vance, Colin; Herich-Terhürne, Dörte; Turki, Amin T.; Schmitz, Christine; Bommer, Martin; Hüttmann, Andreas; Dührsen, Ulrich; Vogel, Ulrich; Röth, Alexander
    Serologic response to meningococcal vaccination in patients with cold agglutinin disease (CAD) in the novel era of complement inhibition
    In: Vaccine Jg. 37 (2019) Nr. 44, S. 6682 - 6687
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Bommer, Martin; Hüttmann, Andreas; Herich-Terhürne, Dörte; Kuklik, Nils; Rekowski, Jan; Lenz, Veronika; Schrezenmeier, Hubert; Dührsen, Ulrich
    Eculizumab in cold agglutinin disease (DECADE) : an open-label, prospective, bicentric, nonrandomized phase 2 trial.
    In: Blood Advances Jg. 2 (2018) Nr. 19, S. 2543 - 2549
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Rottinghaus, Scott T.; Hill, Anita; Bachman, Eric S.; Kim, Jin Seok; Schrezenmeier, Hubert; Terriou, Louis; Urbano-Ispizua, Álvaro; Wells, Richard A.; Jang, Jun Ho; Kulasekararaj, Austin G.; Szer, Jeff; Aguzzi, Rasha; Damokosh, Andrew I.; Shafner, Lori; Lee, Jong Wook
    Ravulizumab (ALXN1210) in patients with paroxysmal nocturnal hemoglobinuria : results of 2 phase 1b/2 studies
    In: Blood Advances Jg. 2 (2018) Nr. 17, S. 2176 - 2185
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Maciejewski, Jaroslaw; Nishimura, Jun-Ichi; Jain, Deepak; Weitz, Jeffrey I.
    Screening and diagnostic clinical algorithm for paroxysmal nocturnal hemoglobinuria : Expert consensus
    In: European Journal of Haematology Jg. 101 (2018) Nr. 1, S. 3 - 11
    Online Volltext: dx.doi.org/
  • Alashkar, Ferras; Schemuth, Haemi Phaedra; Nensa, Felix; Göbel, Juliane; Vance, Colin; Forsting, Michael; Dührsen, Ulrich; Schlosser, Thomas Wilfried; Röth, Alexander
    The Role of Whole-Body Magnetic Resonance Imaging (WB-MRI) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH).
    In: Scientific Reports Jg. 8 (2018) 13458
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ferreri, AJM; Cwynarski, K.; Pulczynski, E.; Fox, C. P.; Schorb, E.; La Rosee, P.; Binder, M.; Fabbri, A.; Torri, V.; Minacapelli, E.; Falautano, M.; Ilariucci, F.; Ambrosetti, A.; Röth, Alexander; Hemmaway, C.; Johnson, P.; Linton, K. M.; Pukrop, T.; Gorlov, J. S.; Balzarotti, M.; Hess, G.; Keller, U.; Stilgenbauer, S.; Panse, J.; Tucci, A.; Orsucci, L.; Pisani, F.; Levis, A.; Krause, S.; Schmoll, H. J.; Hertenstein, B.; Zaccaria, A.; Guarini, A.; Atta, J.; Bassan, R.; Cervetti, J.; Elter, T.; Enggaard, L.; Haenel, M.; Kneba, M.; Liberati, M.; Martelli, M.; Martens, U.; Morra, E.; Pinto, A.; Zaja, F.; Ponzoni, M.; Deckert, M.; Politi, L. S.; Finke, J.; Reni, M.; Cavalli, F.; Zucca, E.; Illerhaus, G.; Int Extranodal Study Grp IELSG
    Autologous stem cell transplantation (ASCT) or whole-brain radiotherapy (WBRT) as consolidation strategies after high-dose methotrexate-based chemoimmunotherapy in patients with newly diagnosed primary cns lymphoma (PCNSL) : results of the IELSG32 randomiz
    In: Bone Marrow Transplantation Jg. 52 (2017) Nr. Suppl. 1, S. 96
  • Alashkar, Ferras; Föhring, Daniel; Dührsen, Ulrich; Baba, Hideo Andreas; Röth, Alexander
    Cytopenia first - hepatitis second : an unusual sequence in aplastic anemia
    In: Clinical Case Reports Jg. 5 (2017) Nr. 6, S. 778 - 781
    Online Volltext: dx.doi.org/ (Open Access)
  • Groth, Martha; Singer, Susanne; Niedeggen, Cathrin; Petermann-Meyer, Andrea; Röth, Alexander; Schrezenmeier, Hubert; Höchsmann, Britta; Brümmendorf, Tim H.; Panse, Jens
    Development of a disease-specific quality of life questionnaire for patients with aplastic anemia and/or paroxysmal nocturnal hemoglobinuria (QLQ-AA/PNH) : report on phases I and II
    In: Annals of Hematology Jg. 96 (2017) Nr. 2, S. 171 - 181
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Maciejewski, J.; Nishimura, J. I.; Jain, D.; Weitz, J.
    Development of a screening and diagnostic algorithm for paroxysmal nocturnal hemoglobinuria using a modified delphi panel methodology
    In: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. S2, S. 224 - 225
  • Kirschner, M.; Bouillon, A. S.; Ferreira, M. V.; Maurer, A.; Wilop, S.; Thol, F.; Röth, Alexander; Platzbecker, U.; Blau, W.; Ayuk, F. A.; Corbacioglu, S.; Schrezenmeier, H.; Manz, M.; Ebel, L.; Koschmieder, S.; Schemionek, M.; Isfort, S.; Panse, J.; Brmmendorf, T. H.; Beier, F.
    Heterozygous RTEL1 variants are associated with bone marrow failure in cryptic dyskeratosis congenita - first results from the Aachen telomere registry
    In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 252
    Online Volltext: dx.doi.org/
  • Kasenda, B.; Ihorst, G.; Schroers, R.; Korfel, A.; Schmidt-Wolf, I.; Egerer, G.; von Baumgarten, L.; Röth, Alexander; Bloehdorn, J.; Möhle, R.; Binder, M.; Keller, U.; Lamprecht, M.; Pfreundschuh, M.; Valk, E.; Fricker, H.; Schorb, E.; Fritsch, K.; Finke, J.; Illerhaus, G.
    High-dose chemotherapy with autologous haematopoietic stem cell support for relapsed or refractory primary CNS lymphoma : a prospective multicentre trial by the German Cooperative PCNSL study group
    In: Leukemia Jg. 31 (2017) Nr. 12, S. 2623 - 2629
    Online Volltext: dx.doi.org/
  • Fritsch, K.; Kasenda, B.; Schorb, E.; Hau, P.; Bloehdorn, J.; Möhle, R.; Löw, S.; Binder, M.; Atta, J.; Keller, U.; Wolf, H.-H.; Krause, S.W.; Heß, G.; Naumann, R.; Sasse, S.; Hirt, C.; Lamprecht, M.; Martens, U.; Morgner, A.; Panse, J.; Frickhofen, N.; Röth, Alexander; Hader, C.; Deckert, M.; Fricker, H.; Ihorst, G.; Finke, J.; Illerhaus, G.
    High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study)
    In: Leukemia Jg. 31 (2017) Nr. 4, S. 846 - 852
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Weber, Susanne N.; Vance, Colin; Herich-Terhürne, Dörte; Dührsen, Ulrich; Lammert, Frank; Röth, Alexander
    Persisting hyperbilirubinemia in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with eculizumab : The role of hepatocanalicular transporter variants
    In: European Journal of Haematology Jg. 99 (2017) Nr. 4, S. 350 - 356
    Online Volltext: dx.doi.org/
  • Oelmuller, M.; Alashkar, F.; Herich-Terhurne, D.; Dührsen, Ulrich; Röth, Alexander
    Response to anti-thymocyte globulin (ATG) in patients with Aplastic Anemia (AA) : a single-centre experience over the last 28 years
    In: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 2, S. 226
  • Alashkar, Ferras; Oelmuller, M.; Herich-Terhürne, D.; Dührsen, Ulrich; Röth, Alexander
    Response to anti-thymocyte globulin (ATG) in patients with Aplastic Anemia (AA) : a single-centre experience over the last 28 years
    In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 31
    Online Volltext: dx.doi.org/
  • Alashkar, Ferras; Vance, Colin; Herich-Terhürne, Dörte; Preising, Nicole; Dührsen, Ulrich; Röth, Alexander
    Serologic response to meningococcal vaccination in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with the terminal complement inhibitor eculizumab
    In: Annals of Hematology Jg. 96 (2017) Nr. 4, S. 589 - 596
    Online Volltext: dx.doi.org/
  • Beier, F.; Kirschner, M.; Bouillon, A. S.; Halfmeyer, I.; Ferreira, MSV; Maurer, A.; Wilop, S.; Thol, F.; Röth, Alexander; Platzbecker, U.; Blau, W.; Ayuk, F. A.; Corbacioglu, S.; Schrezenmeier, H.; Manz, M. G.; Eggermann, T.; Zerres, K.; Koschmieder, S.; Schmemionek, M.; Isfort, S.; Panse, J.; Brummendorf, T. H.
    Telomere lenght screening triggered by clinical suspicion for classical and/or cryptic dyskeratosis congenita - prospective results from the Aachen Telomeropathy Registry
    In: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 2, S. 62
  • Ferreri, Andrés J M; Cwynarski, Kate; Pulczynski, Elisa; Fox, Christopher P; Schorb, Elisabeth; La Rosée, Paul; Binder, Mascha; Fabbri, Alberto; Torri, Valter; Minacapelli, Eleonora; Falautano, Monica; Ilariucci, Fiorella; Ambrosetti, Achille; Röth, Alexander; Hemmaway, Claire; Johnson, Peter; Linton, Kim M; Pukrop, Tobias; Sønderskov Gørløv, Jette; Balzarotti, Monica; Hess, Georg; Keller, Ulrich; Stilgenbauer, Stephan; Panse, Jens; Tucci, Alessandra; Orsucci, Lorella; Pisani, Francesco; Levis, Alessandro; Krause, Stefan W; Schmoll, Hans J; Hertenstein, Bernd; Rummel, Mathias; Smith, Jeffery; Pfreundschuh, Michael; Cabras, Giuseppina; Angrilli, Francesco; Ponzoni, Maurilio; Deckert, Martina; Politi, Letterio S; Finke, Jürgen; Reni, Michele; Cavalli, Franco; Zucca, Emanuele; Illerhaus, Gerald
    Whole-brain radiotherapy or autologous stem-cell transplantation as consolidation strategies after high-dose methotrexate-based chemoimmunotherapy in patients with primary CNS lymphoma : results of the second randomisation of the International Extranodal Lymphoma Study Group-32 phase 2 trial
    In: The Lancet Haematology Jg. 4 (2017) Nr. 11, S. e510 - e523
    Online Volltext: dx.doi.org/
  • Alashkar, Ferras; Schemuth, H.; Herich-Terhurne, D.; Dührsen, Ulrich; Röth, Alexander
    Aortic thrombosis leading to the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 62 - 62
  • Socié, G; Schrezenmeier, H; Muus, P; Lisukov, I; Röth, Alexander; Kulasekararaj, A; Lee, J W; Araten, D; Hill, A; Brodsky, R; Urbano-Ispizua, A; Szer, J; Wilson, A; Hillmen, P
    Changing prognosis in paroxysmal nocturnal haemoglobinuria disease subcategories : an analysis of the International PNH Registry
    In: Internal Medicine Journal Jg. 46 (2016) Nr. 9, S. 1044 - 1053
    Online Volltext: dx.doi.org/
  • Illerhaus, Gerald; Kasenda, Benjamin; Ihorst, Gabriele; Egerer, Gerlinde; Lamprecht, Monika; Keller; Wolf, Hans-Heinrich; Hirt, Carsten; Stilgenbauer, Stephan; Binder, Mascha; Hau, Peter; Edinger, Matthias; Frickhofen, Norbert; Bentz, Martin; Möhle, Robert; Röth, Alexander; Pfreundschuh, Michael; von Baumgarten, Louisa; Deckert, Martina; Hader, Claudia; Fricker, Heidi; Valk, Elke; Schorb, Elisabeth; Fritsch, Kristina; Finke, Jürgen
    High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma : A prospective, single-arm, phase 2 trial
    In: The Lancet Haematology Jg. 3 (2016) Nr. 8, S. e388 - e397
    Online Volltext: dx.doi.org/
  • Alashkar, Ferras; Dührsen, Ulrich; Röth, Alexander
    Horse anti-thymocyte globulin and eculizumab as concomitant therapeutic approach in an aplastic paroxysmal nocturnal hemoglobinuria patient : go or no-go?
    In: European Journal of Haematology Jg. 97 (2016) Nr. 4, S. 403 - 405
    Online Volltext: dx.doi.org/
  • Farsijani, N. M.; Dührsen, Ulrich; Röth, Alexander
    Infection control with granulocyte transfusions in very severe aplastic anemia (VSAA)
    In: Oncology Research and Treatment Jg. 39 3 (2016) S. 62
  • Sellmann, Ludger; Scholtysik, Rene; de Beer, Dirk; Eisele, Lewin; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Düring, Jan; Röth, Alexander; Baerlocher, Gabriele
    Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia
    In: Leukemia and Lymphoma Jg. 57 (2016) Nr. 3, S. 590 - 595
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Bommer, M.; Huttmann, A.; Herich-Terhurne, D.; Kuklik, Nils; Lenz, V.; Schrezenmeier, H.; Dührsen, Ulrich
    The terminal complement inhibitor eculizumab in Cold Agglutinin Disease (CAD) : A prospective phase II trial (DECADE Trial)
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 138 - 138
  • Röth, Alexander; Bommer, Martin; Hüttmann, Andreas; Herich-Terhurne, Dörte; Kuklik, Nils; Lenz, Veronika; Schrezenmeier, Hubert; Dührsen, Ulrich
    Complement Inhibition with Eculizumab in Patients with Cold Agglutinin Disease (CAD) : Results from a Prospective Phase II Trial (DECADE Trial)
    In: Blood Jg. 126 (2015) Nr. 23, S. 274
    Online Volltext: dx.doi.org/ Online Volltext
  • Kelly, Richard J; Höchsmann, Britta; Szer, Jeff; Kulasekararaj, Austin; de Guibert, Sophie; Röth, Alexander; Weitz, Ilene C; Armstrong, Elina; Risitano, Antonio M; Patriquin, Christopher J; Terriou, Louis; Muus, Petra; Hill, Anita; Turner, Michelle P; Schrezenmeier, Hubert; Peffault de Latour, Regis
    Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria
    In: The New England Journal of Medicine Jg. 373 (2015) Nr. 11, S. 1032 - 1039
    Online Volltext: dx.doi.org/ (Open Access)
  • Geisthoff, Urban; Nguyen, Ha-Long; Röth, Alexander; Seyfert, Ulrich
    How to manage patients with hereditary haemorrhagic telangiectasia
    In: British Journal of Haematology Jg. 171 (2015) Nr. 4, S. 443 - 452
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Alashkar, Ferras; Herich-Terhürne, Dörte; Dührsen, Ulrich
    Paroxysmal nocturnal haemoglobinuria : to prednisone or not to prednisone? A case report of a patient previously treated with steroids for 15 yrs and significant response on eculizumab
    In: European Journal of Haematology Jg. 95 (2015) Nr. 2, S. 177 - 180
    Online Volltext: dx.doi.org/
  • Kreher, Stephan; Strehlow, Felicitas; Martus, Peter; Roth, Patrick; Hertenstein, Bernd; Röth, Alexander; Birnbaum, Tobias; Griesinger, Frank; Rauch, Michael; Kanz, Lothar; Thiel, Eckhard; Weller, Michael; Korfel, Agnieszka
    Prognostic impact of intraocular involvement in primary CNS lymphoma : experience from the G-PCNSL-SG1 trial
    In: Annals of Hematology Jg. 94 (2015) Nr. 3, S. 409 - 414
    Online Volltext: dx.doi.org/
  • Korfel, Agnieszka; Thiel, Eckhard; Martus, Peter; Möhle, Robert; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Mergenthaler, Hans G; Junghanß, Christian; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Roth, Patrick; Bamberg, Michael; Pietsch, Torsten; Weller, Michael
    Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma
    In: Neurology Jg. 84 (2015) Nr. 12, S. 1242 - 1248
    Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
  • Baerlocher, Gabriela M; Oppliger Leibundgut, Elisabeth; Ottmann, Oliver G; Spitzer, Gary; Odenike, Olatoyosi; McDevitt, Michael A; Röth, Alexander; Daskalakis, Michael; Burington, Bart; Stuart, Monic; Snyder, David S
    Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia
    In: The New England Journal of Medicine Jg. 373 (2015) Nr. 10, S. 920 - 928
    Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
  • Schubert, Jörg; Röth, Alexander
    Update on paroxysmal nocturnal haemoglobinuria : On the long way to understand the principles of the disease
    In: European Journal of Haematology Jg. 94 (2015) Nr. 6, S. 464 - 473
    Online Volltext: dx.doi.org/
  • Weller, Michael; Thiel, Eckhard; Martus, Peter; Möhle, Robert; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Mergenthaler, Hans-Günter; Junghanss, Christian; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Pietsch, Torsten; Roth, Patrick; Bamberg, Michael; Korfel, Agnieszka; Mergenthaler, H.-G.
    At-59-high-dose MTX-based chemotherapy for primary CNS lymphoma : with or without whole brain radiotherapy? : final analysis of G-PCNSL-SG-1
    In: Neuro-Oncology Jg. 16 (2014) Nr. Suppl.5, S. v21 - v22
    Online Volltext: dx.doi.org/
  • Röth, Alexander
    Selten aber wichtig : Paroxysmale nächtliche Hämoglobinurie (PNH)
    In: Nieren- und Hochdruckkrankheiten Jg. 43 (2014) Nr. 6, S. 281 - 285
  • Goethert, JoachimRud; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Zesewitz, Marie-Loui; Sellmann, Ludger; Röth, Alexander; Pircher, Hanspeter; Dührsen, Ulrich; Dürig, Jan
    Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1(+) effector memory phenotype
    In: Cancer Immunology, Immunotherapy Jg. 62 (2013) Nr. 11, S. 1697 - 1709
    Online Volltext: dx.doi.org/
  • Khandanpour, Cyrus; Dührsen, Ulrich; Röth, Alexander
    Hand-foot syndrome : common presentation in an uncommon situation
    In: European Journal of Haematology Jg. 91 (2013) Nr. 5, S. 472
    Online Volltext: dx.doi.org/
  • Hillmen, Peter; Muus, Petra; Röth, Alexander; Elebute, Modupe O.; Risitano, Antonio M.; Schrezenmeier, Hubert; Szer, Jeffrey; Browne, Paul; Maciejewski, Jaroslaw P.; Schubert, Jörg; Urbano-Ispizua, Alvaro; de Castro, Carlos; Socié, Gérard; Brodsky, Robert A.
    Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria
    In: British Journal of Haematology Jg. 162 (2013) Nr. 1, S. 62 - 73
    Online Volltext: dx.doi.org/ (Open Access)
  • Korfel, Agnieszka; Elter, Thomas; Thiel, Eckhard; Hänel, Matthias; Möhle, Robert; Schroers, Roland; Reiser, Marcel; Dreyling, Martin; Eucker, Jan; Scholz, Christian; Metzner, Bernd; Röth, Alexander; Birkmann, Josef; Schlegel, Uwe; Martus, Peter; Illerhaus, Gerard; Fischer, Lars
    Phase II study of central nervous system (CNS)-directed chemotherapy including high-dose chemotherapy with autologous stem cell transplantation for CNS relapse of aggressive lymphomas
    In: Haematologica / The Hematology Journal Jg. 98 (2013) Nr. 3, S. 364 - 370
    Online Volltext: dx.doi.org/ (Open Access)
  • Föhring, D.; Viala, A.; Dührsen, Ulrich; Röth, Alexander
    Successful treatment of a patient with refractory aquired hemophilia A (AHA) lacking aPTT prolongation with rituximab and intravenous cyclophosphamide
    In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 243
  • Oppliger Leibundgut, Elisabeth; Rogenmoser-Dissler, Daniela; de Beer, Dirk; Porret, Naomi A.; Zibellini, Silvia; Dürig, Jan; Röth, Alexander; Klingbiel, Dirk; Baerlocher, Gabriela M.
    CLLU1 expression distinguishes chronic lymphocytic leukemia from other mature B-cell neoplasms
    In: Leukemia Research Jg. 36 (2012) Nr. 9, S. 1204 - 1207
    Online Volltext: dx.doi.org/
  • Johansson, Patricia; Metz, Klaus; Dührsen, Ulrich; Röth, Alexander
    Chronic lymphocytic leukemia gone osteolytic : a case report
    In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 217 - 218
  • Röth, Alexander; Schmücker, U.; Tokareva, O.; Preising, N.; Hock, C.; Dührsen, Ulrich
    Fate of GPI-deficient clones in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) : a retrospective analysis
    In: Onkologie Jg. 35 (2012) Nr. 6, S. 24
  • Baerlocher, Gabriela M.; Leibundgut, Elisabeth O.; Ayran, Christina; Blaney, Martha; Burington, Bart; Morfeld, Dianne; Odenike, Olatoyosi; Ottman, Oliver; Reddy, Anita; Röth, Alexander; Spitzer, Gary; Stuart, Monic J.; Verstovsek, Srdan; Snyder, David S.
    Imetelstat Rapidly Induces and Maintains Substantial Hematologic and Molecular Responses in Patients with Essential Thrombocythemia (ET) Who Are Refractory or Intolerant to Prior Therapy : Preliminary Phase II Results
    In: Blood Jg. 120 (2012) Nr. 21,
  • Roth, Patrick; Martus, Peter; Kiewe, Philipp; Möhle, Robert; Klasen, Hermann Ayke; Rauch, Michael; Röth, Alexander; Kaun, Stephan; Thiel, Eckhard; Korfel, Agnieszka; Weller, Michael
    Outcome of elderly patients with primary CNS lymphoma in the G-PCNSL-SG-1 trial
    In: Neurology Jg. 79 (2012) Nr. 9, S. 890 - 896
    Online Volltext: dx.doi.org/
  • Korfel, Agnieszka; Weller, Michael; Martus, Peter; Roth, Patrick; Klasen, Hermann Ayke; Röth, Alexander; Rauch, Michael; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Leithäuser, Malte; Birnbaum, Tobias; Kirchen, Heinz; Mergenthaler, Hans-Günther; Schubert, Jan; Berdel, Wolfgang; Birkmann, Josef; Hummel, Michael; Thiel, Eckhard; Fischer, Lars
    Prognostic impact of meningeal dissemination in primary CNS lymphoma (PCNSL) : experience from the G-PCNSL-SG1 trial
    In: Annals of Oncology Jg. 23 (2012) Nr. 9, S. 2374 - 2380
    Online Volltext: dx.doi.org/ (Open Access)
  • Marsh, Judith C.; Bacigalupo, Andrea; Schrezenmeier, Hubert; Tichelli, Andre; Risitano, Antonio M.; Passweg, Jakob R.; Killick, Sally B.; Warren, Alan J.; Foukaneli, Theodora; Aljurf, Mahmoud; Al-Zahrani, H. A.; Schafhausen, Philip; Roth, Alexander; Franzke, Anke; Brummendorf, Tim H.; Dufour, Carlo; Oneto, Rosi; Sedgwick, Philip; Barrois, Alain; Kordasti, Shahram; Elebute, Modupe O.; Mufti, Ghulam J.; Socie, Gerard
    Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party
    In: Blood Jg. 119 (2012) Nr. 23, S. 5391 - 5396
    Online Volltext: dx.doi.org/
  • Illerhaus, Gerald; Fritsch, Kristina; Egerer, G.; Lamprecht, M.; von Bubnoff, Niklas; Wolf, H. H.; Dolken, G.; Stilgenbauer, S.; Panse, J.; Balabanov, S.; Hau, P.; Frickhofen, N.; Bentz, M.; Röth, Alexander; Mohle, R.; Birnbaum, T.; Pfreundschuh, M.; Hader, C.; Ihorst, G.; Deckert, M.; Prinz, M.; Schorb, E.; Fricker, H.; Kasenda, B.; Finke, J.
    Sequential High Dose Immuno-Chemotherapy Followed by Autologous Peripheral Blood Stem Cell Transplantation for Patients with Untreated Primary Central Nervous System Lymphoma - a Multicentre Study by the Collaborative PCNSL Study Group Freiburg
    In: Blood Jg. 120 (2012) Nr. 21, -
  • Sellmann, Ludger; Scholtysik, R.; Klein-Hitpaß, Ludger; Nückel, Holger; Dührsen, Ulrich; Röth, Alexander
    Significance of chromosomal aberrations and HMGA2 expression in Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 220 - 221
  • Hanoun, Maher; Röth, Alexander; Dührsen, Ulrich; Brock, Franz-Eduard
    Acral ischemia as a presenting manifestation of essential thrombocythemia
    In: International Journal of Hematology Jg. 94 (2011) Nr. 3, S. 219 - 220
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Dührsen, Ulrich; Christoph, Sandra; Hock, Christina; Konik, Anna
    Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab : safety, efficacy, and unexpected laboratory phenomena
    In: International Journal of Hematology Jg. 93 (2011) Nr. 6, S. 704 - 714
    Online Volltext: dx.doi.org/
  • Schrezenmeier, Hubert; Bettelheim, Peter; Panse, Jens; Schubert, Joerg; Hochsmann, Britta; Röth, Alexander; Nebe, Thomas
    Empfehlungen zur Diagnostik der Paroxysmalen nächtlichen Hämoglobinurie : deutsch – österreichischer Konsensus
    In: Laboratoriumsmedizin Jg. 35 (2011) Nr. 6, S. 315 - 327
    Online Volltext: dx.doi.org/
  • Korfel, A.; Fischer, L.; Martus, P.; Moehle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Mergenthaler, H.; Hundsberger, T.; Leithäuser, M.; Birnbaum, T.; Florschütz, A.; Jahnke, Klaus; Herrlinger, U.; Weller, M.; Thiel, E.
    Impact of meningeal dissemination (MD) on outcome in primary CNS lymphoma in the G-PCNSL-SG1 trial
    In: Journal of Clinical Oncology (JCO) Jg. 29 (2011) Nr. 15_suppl, S. 2026
    Online Volltext: dx.doi.org/
  • Martus, P.; Jahnke, Klaus; Korfel, A.; Rose, T.; Fischer, L.; Moehle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H.; Leithäuser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Birkmann, J.; Weller, M.; Thiel, E.
    Prognostic factors for chemotherapy-related toxicity in primary central nervous system lymphoma (PCNSL) treated with high-dose methotrexate (HDMTX) with or without ifosfamide: Results from a German phase III trial (G-PCNSL-SG-1)
    In: Journal of Clinical Oncology (JCO) Jg. 29 (2011) Nr. 15_suppl, S. 2005
    Online Volltext: dx.doi.org/
  • Jahnke, Klaus; Korfel, A.; Martus, P.; Lokka, S.; Moehle, R.; Griesinger, F.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H.; Leithäuser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Florschütz, A.; Fischer, L.; Weller, M.; Thiel, E.
    Prognostic factors for response and survival in primary central nervous system lymphoma (PCNSL) from a randomized phase III trial (G-PCNSL-SG-1)
    In: Journal of Clinical Oncology (JCO) Jg. 29 (2011) Nr. 15_suppl, S. 2004
    Online Volltext: dx.doi.org/
  • Sellmann, Ludger; Röth, Alexander; Baerlocher, Gabriela M.; Küppers, Ralf; Siemer, Dörte; Seifert, Marc; Dürig, Jan; Dührsen, Ulrich; Nückel, Holger; Opalka, Bertram; Bartels, Marius; de Beer, Dirk
    Telomeres and prognosis in patients with chronic lymphocytic leukaemia
    In: International Journal of Hematology Jg. 93 (2011) Nr. 1, S. 74 - 82
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Dührsen, Ulrich
    Treatment of paroxysmal nocturnal hemoglobinuria in the era of eculizumab
    In: European Journal of Haematology Jg. 87 (2011) Nr. 6, S. 473 - 479
    Online Volltext: dx.doi.org/
  • Hanoun, Maher; Schmitz, Klaus Jürgen; Dührsen, Ulrich; Röth, Alexander
    Amyloid tumour
    In: British Journal of Haematology Jg. 150 (2010) Nr. 4, S. 387
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Dührsen, Ulrich
    Cold agglutinine disease
    In: European Journal of Haematology Jg. 84 (2010) Nr. 1, S. 91
    Online Volltext: dx.doi.org/
  • Thiel, Eckhard; Korfel, Agnieszka; Martus, Peter; Kanz, Lothar; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; von Toll, Theda; Hundsberger, Thomas; Mergenthaler, Hans-Günther; Leithäuser, Malte; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Plasswilm, Ludwig; Nägele, Thomas; Pietsch, Torsten; Bamberg, Michael; Weller, Michael
    High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1) : a phase 3, randomised, non-inferiority trial
    In: The Lancet Oncology Jg. 11 (2010) Nr. 11, S. 1036 - 1047
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Hüttmann, Andreas; Dührsen, U.; Philipp, Thomas;
    Inhibition of the Terminal Complement System Using Eculizumab for the Treatment of Cold Agglutinin Disease (CAD)
    184. Tagung der Rheinisch-Westfälischen Gesellschaft für Innere Medizin e.V.,
    In: Medizinische Klinik Jg. 105 (2010) Nr. 3, S. 213 - 214
    Online Volltext: dx.doi.org/
  • Christoph, S.; Sellmann, Ludger; Röth, Alexander; Elmaagacli, Ahmet Hayri; Beelen, Dietrich; Dührsen, Ulrich;
    Intraperitoneal and intrapleural application of Rituximab in refractory CD20-positive B-cell lymphoma
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 253
    Online Volltext: dx.doi.org/
  • Konik, A.; Dührsen, Ulrich; Röth, Alexander;
    Longitudinal analysis of the monospecific coombs test in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) chronically treated with Eculizumab
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 50
    Online Volltext: dx.doi.org/
  • Konik, Anna; Dührsen, Ulrich; Röth, Alexander
    Nodular lesions of the scalp and a mediastinal mass in T cell acute lymphoblastic leukemia
    In: International Journal of Hematology Jg. 92 (2010) Nr. 1, S. 3 - 4
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Peine, Sven; Dührsen, Ulrich
    Paroxysmal nocturnal hemoglobinuria turning Coombs-positive
    In: International Journal of Hematology Jg. 91 (2010) Nr. 2, S. 159 - 160
    Online Volltext: dx.doi.org/
  • Christoph, Sandra; Hüttmann, Andreas; Dührsen, Ulrich; Röth, Alexander
    Porphyria cutanea tarda
    In: British Journal of Haematology Jg. 148 (2010) Nr. 4, S. 493
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Schubert, J.; Schrezenmeier, Hubert; Dührsen, Ulrich
    Paroxysmale nächtliche Hämoglobinurie (PNH) : Pathogenese, Diagnostik und Therapie
    In: Deutsche Medizinische Wochenschrift - DMW Jg. 134 (2009) Nr. 9, S. 404 - 409
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Baerlocher, Gabriela M.
    Telomere Biology in T Cells : An Important Brake on the Road of Their Life Span?
    In: Clinical leukemia Jg. 3 (2009) Nr. 1, S. 41 - 46
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Baerlocher, Gabriela M.
    Dyskeratosis congenita
    In: British Journal of Haematology Jg. 141 (2008) Nr. 4, S. 412
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Dührsen, Ulrich
    Paroxysmale nächtliche Hämoglobinurie (PNH) : Aktuelle Diagnostik und Therapieansätze
    In: Arzneimitteltherapie (AMT) (2008) Nr. 3, S. 96 - 101
  • Röth, Alexander; de Beer, Dirk; Nückel, Holger; Sellmann, Ludger; Dührsen, Ulrich; Baerlocher, Gabriele M.
    Significantly shorter telomeres in T-cells of patients with ZAP-70+/CD38+ chronic lymphocytic leukaemia
    In: British Journal of Haematology Jg. 143 (2008) Nr. 3, S. 383 - 386
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Dührsen, Ulrich; Baerlocher, Gabriele M.; Himmelreich, H.; Schneider, L.
    Impact of culture conditions on the proliferative lifespan of human T cells in vitro
    In: Cytotherapy : official journal of ISCT, the International Society for Cellular Therapy Jg. 9 (2007) Nr. 1, S. 91 - 98
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Dürig, Jan; Himmelreich, H.; Bug, S.; Siebert, Reiner; Dührsen, Ulrich; Lansdorp, M.; Baerlocher, Gabriele
    Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia
    In: Leukemia Jg. 21 (2007) Nr. 12, S. 2456 - 2462
    Online Volltext: dx.doi.org/
  • Hillmen, Peter; Luzzatto, Lucio; Rother, Russel P.; Mojcik, Christopher F.; Rollins, Scott A.; Maciejewski, Jaroslaw; Fu, Chieh-Lin; Schrezenmeier, Hubert; Hill, Anita; Risitano, Antonio M.; Browne, Paul; Nakamura, Ryotaro; Elebute, Modupe O.; Szer, Jeffrey; Röth, Alexander; Muus, Petra; Socié, Gerard; Brodsky, Robert A.; Schubert, Jörg; Young, Neal S.
    The complement inhibitor Eculizumab in paroxysmal nocturnal hemoglobinuria
    In: The New England Journal of Medicine Jg. 355 (2006) Nr. 12, S. 1233 - 1243
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Lansdorp, Peter M.; Dührsen, Ulrich; Chavez, Elisabeth; Schertzer, Mike; Baerlocher, Gabriele M.
    Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT
    In: Blood Jg. 106 (2005) Nr. 1, S. 43 - 50
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Sutherland, H.J.; Lansdorp, P.M.; Vercauteren, S.
    Telomerase is limiting the growth of acute myeloid leukemia cells
    In: Leukemia Jg. 17 (2003) Nr. 12, S. 2410 - 2417
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Luiten, Rosalie M.; Spits, Hergen; Lansdorp, Peter M.; Schertzer, Mike; Chavez, Elizabeth A.; Pène, Jerome; Yssel, Hans
    Telomerase levels control the lifespan of human T lymphocytes
    In: Blood Jg. 102 (2003) Nr. 3, S. 849 - 857
    Online Volltext: dx.doi.org/

    • Abstracts

  • Röth, Alexander; Barcellini, Wilma; Ademokun, Christine; Chitnis, Shripad; Matviykiv, Sofiya; Vitaliti, Alessandra; Chen, Chi; Katsanou, Vasiliki; Chawla, Raghav; Al-Samkari, Hanny
    Iptacopan Monotherapy in Patients with Cold Agglutinin Disease : Phase II Study Results
    In: Blood Jg. 144 (2024) Nr. Supplement 1, S. 2457
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin G.; Czyz, Jaroslaw; Flynn, Catherine; Gastal, Gabriela Roncone; Hus, Marek; Lalayanni, Chrysavgi; Nur, Erfan; Scheinberg, Phillip; Ueda, Yasutaka; Vannucchi, Alessandro Maria; Vidriales Vicente, Maria; Viigimaa, Iige; Buatois, Simon; Chang, Alice C.; Chebon, Sammy; Röth, Alexander
    Phase III COMMODORE 2 and 1 Trials : Characterization of Breakthrough Hemolysis Events in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab or Eculizumab
    In: Blood Jg. 144 (2024) Nr. Supplement 1, S. 1323 - 1325
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Wang, Jennifer; Vagge, Deepthi S.; Wardęcki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.
    26 Sustained complement C1s inhibition with sutimlimab in patients with cold agglutinin disease results in continued efficacy during part B of the randomized placebo-controlled phase 3 CADENZA study (NCT03347422)
    In: Immunobiology Jg. 228 (2023) Nr. 5, 152483
    Online Volltext: dx.doi.org/
  • Lundberg, Pontus; de la Iglesia, Silvia; Kelly, Richard J; Kulasekararaj, Austin; Nishimura, Jun-Ichi; Risitano, Antonio M; Röth, Alexander; Buatois, Simon; Chebon, Sammy; Patel, Himika; Kiialainen, Anna
    Biomarker Analyses in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Eculizumab : Results from the Phase III Randomized COMMODORE 2 Trial
    In: Blood Jg. 142 (2023) Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 4088 - 4088
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Barcellini, Wilma; Jaeger, Ulrich; Ueda, Yasutaka; Michel, Marc; Hill, Quentin A.; Srivastava, Shruti; Yoo, Ronnie; Broome, Catherine M.;
    Cold Agglutinin Disease (CAD) Real-World Evidence (CADENCE) Registry : Update to the Study Design of the First International, Prospective CAD Registry
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 7341 - 7342
    Online Volltext: dx.doi.org/ (Open Access)
  • Broome, Catherine M.; Barcellini, Wilma; Ueda, Yasutaka; Khan, Umer; Patel, Reena; Wardęcki, Marek; Kralova, Katarina; Srivastava, Shruti; Röth, Alexander
    Combined Safety Data for Sutimlimab in Cold Agglutinin Disease: : A Post-Hoc Analysis of the Phase 3 Cardinal and Cadenza Studies
    In: Blood Jg. 142 (2023) Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 3833 - 3833
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Peffault de Latour, R.; Kulasekararaj, A.; Risitano, A. M.; et al.;
    Efficacy and safety of oral therapy with iptacopan compared to standard intravenous therapy with eculizumab or ravulizumab in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) : results of the randomized controlled open-label multicenter phase III study APPLY-PNH
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 42 - 44
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Weitz, Ilene; Ueda, Yasutaka; Bozzi, Sylvie; Patel, Reena; Karaouni, Alia; Yoo, Ronnie; Cella, David; Wang, Jennifer;
    Efficacy of Sutimlimab in Improving FACIT-Fatigue Scores in Patients with Cold Agglutinin Disease : A Post-Hoc Analysis of the Phase 3 Cadenza (Part A) Study
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 5558 - 5560
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, Antonio M; Kulasekararaj, Austin; Röth, Alexander; Scheinberg, Phillip; Ueda, Yasutaka; de Castro, Carlos; Di Bona, Eros; Griffin, Morag; Langemeijer, Saskia MC; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor AQ; Panse, Jens; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Gaya, Anna; Huang, Wei-Han; Kitawaki, Toshio; Kutlar, Abdullah; Maciejewski, Jaroslaw P.; Notaro, Rosario; Pullarkat, Vinod; Schubert, Jörg; Terriou, Louis; Uchiyama, Michihiro; Sicre De Fontbrune, Flore; Frieri, Camilla; Alashkar, Ferras; Gandhi, Shreyans; Kumar, Rakesh; Thorburn, Christine; Maitra, Samopriyo; Solar-Yohay, Susan; Lawniczek, Tomasz; Dahlke, Marion; Peffault De Latour, Régis;
    Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia : Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial
    65th Annual Meeting of the American-Society-of-Hematology (ASH); DEC 09-12, 2023; San Diego, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 571 - 571
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Risitano, A. M.; Han, B.; Peffault de Latour, R.; et al.;
    Oral therapy with the complement factor B inhibitor iptacopan increases hemoglobin concentration and relieves fatigue symptoms in complement inhibitor-naive adults with paroxysmal nocturnal hemoglobinuria : Results of the single-arm, open-label, multicenter phase III APPOINT-PNH study
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 45
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin; Gonzalez Fernandez, Fernando Ataulfo; Scheinberg, Phillip; Straetmans, Nicole; Ueda, Yasutaka; Gentile, Brittany; Stefani, Jennifer; Uguen, Marianne; Röth, Alexander;
    Patient Preferences and Treatment Satisfaction in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Approved C5 Inhibitors in the Phase III Randomized COMMODORE 1 and COMMODORE 2 Trials
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 5628 - 5630
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Patriquin, Christopher J.; Szer, Jeff; Terriou, Louis; Patel, Ami; Gustovic, Philippe; Nishimura, Jun-Ichi; Brodsky, Robert A.
    Ravulizumab Effectiveness in the Real World : Evidence from the International PNH Registry
    In: Blood Jg. 142 (2023) Nr. Supplement 1: Annual Meeting Abstracts (65th ASH Annual Meeting and Exposition, 9-12 Dezember 2023, San Diego), S. 2722 - 2722
    Online Volltext: dx.doi.org/ (Open Access)
  • Majerus, Elaine M; Mulherin, Brian; Wilson, Koo; Fishman, Jesse; Mellor, Jennifer; Earl, Lucy; Röth, Alexander;
    Real-World Treatment Outcomes of Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated with Pegcetacoplan and Complement Protein 5 Inhibitors (C5i)
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 5633 - 5634
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; FU, Rong; He, Guangsheng; Alzahrani, Hazza A; Chou, Sheng-Chieh; Hicheri, Yosr; Kazmierczak, Maciej; Lacorte Recova, Viviane; Uchiyama, Michihiro; Vladareanu, ANA Maria; Beveridge, Leigh; Buatois, Simon; Buri, Muriel; Shi, Dayu; Balachandran, Nadiesh; Srekovic, Sasha; Scheinberg, Phillip;
    Safety of Crovalimab Versus Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) : Pooled Results from the Phase III COMMODORE 1, COMMODORE 2, and COMMODORE 3 Studies
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 575 - 577
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Berentsen, S.; Barcellini, W.; Broome, C. M.; et al.;
    Sustained complement C1s inhibition with sutimlimab in patients with cold agglutinin disease results in continued efficacy during part B of the randomized placebo-controlled phase 3 CADENZA study (NCT03347422)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 120
    Online Volltext: dx.doi.org/ (Open Access)
  • Schorb, E.; Isbell, L.; Kerkhoff, A.; Röth, Alexander; Illerhaus, G.; et al.; Kooperative Studiengruppe ZNS-Lymphome;
    Altersadaptierte Hochdosistherapie und autologe Stammzelltransplantation bei älteren Patienten mit Erstdiagnose eines primären ZNS-Lymphoms : die Phase II MARTA Studie
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 59
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Alashkar, Ferras; Panse, J.; Sockel, K.; Haferlach, T.; Hübel, K.; Blau, I. W.; Platzbecker, U.; Höchsmann, B.; Schrezenmeier, H.;
    Ausgangscharakteristika von Patienten mit Paroxysmaler Nächtlicher Hämoglobinurie (PNH) : Daten aus dem Deutschen PNH-Register einschließlich Eculizumab, Ravulizumab und unbehandelten Patienten
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 174
    Online Volltext: dx.doi.org/ (Open Access)
  • Fattizzo, Bruno; Röth, Alexander; Broome, Catherine M.; Khan, Umer; Shafer, Frank; Cordoba, Matias; Barcellini, Wilma
    Concomitant Use of Sutimlimab and COVID-19 Vaccines in Patients with Cold Agglutinin Disease from the Phase 3 Cardinal and Cadenza Studies
    In: Blood Jg. 140 (2022) Nr. Suppl. 1, S. 2839 - 2841
    Online Volltext: dx.doi.org/ (Open Access)
  • Illerhaus, Gerald; Ferreri, Andrés J.M.; Binder, Mascha; Borchmann, Peter; Hasenkamp, Justin; Stilgenbauer, Stephan; Roeth, Alexander; Weber, Thomas; Egerer, Gerlinde; Ernst, Thomas; Hertenstein, Bernd; Lenz, Georg; Kobbe, Guido; Brunnberg, Uta; Schmidt, Christian; Kneba, Michael; Dreyling, Martin; Möhle, Robert; Panse, Jens; Heinicke, Thomas; Schroll, Sebastian; Larsen, Thomas S.; Salwender, Hans; Naumann, Ralph; Hess, Georg; Thurner, Lorenz; Pukrop, Tobias; Keller, Ulrich; Blystadt, Anne Kirsti; Kroschinsky, Frank P.; Re, Francesca; Pulczynski, Elisa; Orsucci, Lorella; Pospiech, Lisa; Deckert, Martina; Ponzoni, Maurilio; Wendler, Julia; Valk, Elke; Calimeri, Teresa; Kasenda, Benjamin; Trepel, Martin; Fricker, Heidi; von Gottberg, Philipp; Burger, Elvira; Ihorst, Gabriele; Grishina, Olga; Hader, Claudia; Zucca, Emanuele; Finke, Jürgen; Schorb, Elisabeth;
    Effects on Survival of Non-Myeloablative Chemoimmunotherapy Compared to High-Dose Chemotherapy followed by Autologous Stem Cell Transplantation (HDC-ASCT) as Consolidation Therapy in Patients with Primary CNS Lymphoma : Results of an International Randomized Phase III Trial (MATRix/IELSG43)
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 2, S. 10 - 13
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Peffault de Latour, R.; Soret, J.; Frieri, C.; Sicre de Fontbrune, F.; Marano, L.; Alashkar, Ferras; Benajiba, L.; Marotta, S.; Kulmatycki, K.; Nidamarthy, P. K.; Fagan, N.; Junge, G.; Risitano, A. M.;
    Einsatz des oralen Komplementfaktor B-Inhibitors Iptacopan bei Patienten (pts) mit Paroxysmaler Nächtlicher Hämoglobinurie (PNH) mit anhaltende Hämolyse trotz einer Anti-C5 Therapie : langfristige Wirksamkeit und Sicherheit nach dem Absetzen von Eculizumab (ECU)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 173 - 174
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Berentsen, S.; Barcellini, W.; D‘Sa, S.; Jilma, B.; Michel, M.; Weitz, I. C.; Yamaguchi, M.; Nishimura, J.-i.; Vos, J. M.; Storek, M.; Wong, N. W.; Patel, P.; Jiang, X.; Vagge, D.; Wardęcki, M.; Shafer, F.; Lee, M.; Broome, C. M.;
    Hemmung von Komplement C1s durch Sutimlimab (SUT) bei Patienten mit Cold Agglutinin Disease (CAD) : Ergebnisse zur Wirksamkeit und Sicherheit aus der randomisierten, placebokontrollierten Phase-3 CADENZA-Studie (NCT03347422)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 172 - 173
    Online Volltext: dx.doi.org/ (Open Access)
  • Broome, Catherine M.; Barcellini, Wilma; Röth, Alexander; Karaouni, Alia; Joly, Florence; Yoo, Ronnie; Terlinden, Augustin; Adeyemi, Ayo; Moride, Yola; Hill, Quentin A.;
    Hemolytic Markers, Mortality, and Thromboembolic Events in Cold Agglutinin Disease (CAD) : A Retrospective Analysis of the Optum Electronic Health Record Database in the United States
    64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH): DEC 10-13, 2022; New Orleans, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 5306 - 5308
    Online Volltext: dx.doi.org/ (Open Access)
  • Schorb, Elisabeth; Isbell, Lisa; Kerkhoff, Andrea; Mathas, Stephan; Braulke, Friederike; Egerer, Gerlinde; Roeth, Alexander; Schliffke, Simon Christian; Borchmann, Peter; Brunnberg, Uta; Kroschinsky, Frank P.; Möhle, Robert; Rank, Andreas; Wellnitz, Dominique; Kasenda, Benjamin; Pospiech, Lisa; Wendler, Julia; Ihorst, Gabriele; Scherer, Florian; Deckert, Martina; Henkes, Elina; Duyster, Justus; Finke, Jürgen; Illerhaus, Gerald;
    High-Dose Chemotherapy and Autologous Stem Cell Transplant in Elderly and Fit Primary CNS Lymphoma Patients : a Multicenter Study By the Cooperative PCNSL Study Group (MARTA study)
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 1773 - 1774
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Lange, C. P.; Yamamoto, R.; Reinhardt, H. Christian; Röth, Alexander;
    Luspatercept bei Patienten mit transfusionsabhängiger β-Thalassämie : die erste reale Analyse
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 49
    Online Volltext: dx.doi.org/ (Open Access)
  • Peffault de Latour, Regis; Roeth, Alexander; Kulasekararaj, Austin; Scheinberg, Phillip; Ueda, Yasutaka; de Castro, Carlos M; Di Bona, Eros; Schrezenmeier, Hubert; Langemeijer, Saskia MC; Barcellini, Wilma; Tavitian, Suzanne; Panse, Jens; Schafhausen, Philippe; Mauad, Vitor AQ; Kerloeguen, Cecile; Levitch, Rafael; Kumar, Rakesh; Thorburn, Christine; Maitra, Samopriyo; Dahlke, Marion; Risitano, Antonio M;
    Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia : Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 2, S. 5 - 9
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Roeth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Tvedt, Tor Henrik Anderson; Yamaguchi, Masaki; Murakhovskaya, Irina; Lee, Michelle; Shafer, Frank; Wardecki, Marek; Wang, Jennifer; Yoo, Ronnie; Mshijid, Jerome; Weitz, Ilene C.;
    Sutimlimab Provides Sustained Improvements in Patient-Reported Outcomes and Quality of Life in Patients with Cold Agglutinin Disease : Open-Label Extension of the Randomized, Phase 3 Cadenza Study
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 70 - 72
    Online Volltext: dx.doi.org/ (Open Access)
  • Jilma, Bernd; Roman, Eloy; Ueda, Yasutaka; Mappa, Silvia; Szamosi, Johan; Savage, Jessica; Röth, Alexander
    Trial in Progress : Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients with Cold Agglutinin Disease (CASCADE)
    In: Blood Jg. 140 (2022) Nr. Suppl. 1, S. 5326 - 5327
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Röth, Alexander; Reinhardt, H. Christian; Franzen, C.; Peetz, J.; Papathanasiou, Maria; Reinhardt, Dirk; Halimeh, S.; Aramayo-Singelmann, C.;
    Voxelotor bei Jugendlichen und Erwachsenen mit Sichelzellkrankheit : erste Erfahrungen aus dem deutschen Härtefallprogramm
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 48
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Berentsen, S.; Barcellini, W.; D’Sa, S.; Jilma, B.; Michel, M.; Weitz, I.C.; Yamaguchi, M.; Nishimura, J.-I.; Jos, J. M. I.; Patel, P.; Schaible, B.; Jiang, X.; Vagge, D. S.; Wardęcki, M.; Shafer, F.; Lee, M.; Broome, C. M.;
    C1s-targeted inhibition of classical complement pathway by sutimlimab in cold agglutinin disease (CAD) : Efficacy and safety results from the randomized, placebo (PBO)-controlled phase 3 CADENZA study
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 40 - 41
    Online Volltext: dx.doi.org/ (Open Access)
  • Beier, Fabian; Tometten, Mareike; Kirschner, Martin; Halfmeyer, Insa; Vieri, Margherita; Kricheldorf, Kim; Maurer, Angela; Röth, Alexander; Platzbecker, Uwe; Radsak, Markus P.; Schafhausen, Philippe; Corbacioglu, Selim; Hoechsmann, Britta; Wilk, C. Matthias; Hinze, Claas; Chromik, Jörg; Egle, Alexander; Heuser, Michael; Kreuter, Michael; Kurth, Ingo; Koschmieder, Steffen; Panse, Jens; Meyer, Robert; Isfort, Susanne; Brummendorf, Tim H;
    Clinical Presentation of Patients with Adult Late-Onset Telomere Biology Disorders : Results from the Aachen Telomeropathy Registry
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 1130 - 1132
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Hoechsmann, Britta; Griffin, Morag; De Castro, Carlos M.; Szer, Jeffrey; Usuki, Kensuke; Soret, Juliette; Hamdani, Mohamed; Ajayi, Temitayo; Sarda, Sujata P.; Panse, Jens;
    Effect of Pegcetacoplan on Quality of Life in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Pegasus Phase 3 Trial Comparing Pegcetacoplan to Eculizumab
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology Jg. 193 (2021) Nr. S1, S. 198 - 199
    Online Volltext: dx.doi.org/ (Open Access)
  • Panse, J.; Höchsmann, B.; Griffin, M.; De Castro, C. M.; Szer, J.; Usuki, K.; Soret, J.; Al-Adhami, M.; Chen, C.; Sarda, S. P.; Röth, Alexander;
    Effect of Pegcetacoplan on quality of life in patients with Paroxysmal Nocturnal Hemoglobinuria : Week 48 of PEGASUS phase 3 trial comparing Pegcetacoplan to Eculizumab
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 41 - 42
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander;
    Efficacy and Safety at 48 Weeks of Pegcetacoplan in Adult Paroxysmal Nocturnal Hemoglobinuria Patients with Suboptimal Response to Prior Eculizumab Treatment
    Society of Hematologic Oncology 9th Annual Meeting ; September 8–11, 2021, Houston, Texas, USA & Virtual Venue,
    In: Clinical Lymphoma, Myeloma & Leukemia Jg. 21 (2021) Nr. Suppl. 1, S. S341 - S342
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Lenderking, William R.; Sarda, Sujata P.; Baver, Scott B.; Hamdani, Mohamed; Hsieh, Ray; Shaffer, Shannon; Yeh, Michael; Cella, David
    Improvements in Fatigue And Physical Function Evaluated Through Changes in Clinical Outcomes In Paroxysmal Nocturnal Hemoglobinuria : Post-HOC Analyses From The Pegasus Study
    In: Bone Marrow Transplantation Jg. 56 (2021) Nr. Suppl. 1, S. 149 - 150
  • Röth, Alexander; Lenderking, William R; Sarda, Sujata P.; Baver, Scott B.; Hamdani, Mohamed; Hsieh, Ray; Shaffer, Shannon; Yeh, Michael; Cella, David;
    Improvements in Fatigue and Physical Function Evaluated Through Changes in Clinical Outcomes in Paroxysmal Nocturnal Hemoglobinuria : Post-Hoc Analyses from the PEGASUS Study
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology Jg. 193 (2021) Nr. S1, S. 195
    Online Volltext: dx.doi.org/
  • Barcellinia, W.; Röth, Alexander; D'Sa, S.; Berentsen, S.; et al.;
    Inhibition of Complement C1S with Sutimlimab in Patients with Cold Agglutinin Disease (CAD) : Interim Results of the Phase 3 Cardinal Study Long-Term Follow-up
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. S3: Abstract Book, 48th Congress of the Italian Society of Hematology, 24-27 October 2021, S. 107
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-Ichi; Vos, Josephine M.I.; Storek, Michael; Wong, Nancy; Patel, Parija; Schaible, Braydon; Jiang, Xiaoyu; Vagge, Deepthi; Wardecki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.;
    Inhibition of Complement C1s By Sutimlimab in Patients with Cold Agglutinin Disease (CAD) : Efficacy and Safety Results from the Randomized, Placebo-Controlled Phase 3 CADENZA Study
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 349 - 351
    Online Volltext: dx.doi.org/ (Open Access)
  • Calimeri, T.; Cwynarski, K.; Pulczynski, E.; Röth, Alexander; Ferreri, A. J. M.; et al.;
    Results of the IELSG32 Trial at a Median Follow-Up of 88 Months Demonstrate that Matrix Followed by Autologous Transplant is Associated with Excellent Survival and Neurotolerabilty in Patients with Primary CNS Lymphoma
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. 10, S3: 48th Congress of the Italian Society of Hematology, 24-27 October 2021, S. 33
    Online Volltext: dx.doi.org/ (Open Access)
  • Griffin, Morag; Hillmen, Peter; Szer, Jeffrey; Weitz, Ilene C.; Röth, Alexander; Hoechsmann, Britta; Panse, Jens; Usuki, Kensuke; Kiladjian, Jean-Jacques; De Castro, Carlos M.; Nishimori, Hisakazu; Tan, Lisa; Hamdani, Mohamed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio; De Latour, Regis Peffault
    Results of the Pegasus Phase 3 Randomized Trial Demonstrating Superiority of the C3 Inhibitor, Pegcetacoplan, Compared to Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria
    In: British Journal of Haematology Jg. 193 (2021) Nr. S1,
    Online Volltext: dx.doi.org/ (Open Access)
  • Hoechsmann, B.; Hill, A.; de Latour, R. Peffault; Röth, Alexander; Devos, T.; Patriquin, C.; Chou, W. C.; Jain, D.; Zu, K.; Lee, J. W.;
    Risk Factors for Thrombotic Events in Patients with PNH : A Nested Case-Control Study in the International PNH Registry
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology Jg. 193 (2021) Nr. S1, S. 193 - 194
    Online Volltext: dx.doi.org/
  • Barcellini, Wilma; Röth, Alexander; Anderson Tvedt, T. H.; Weitz, I. C.; et al.;
    Sutimlimab, a Complement C1S Inhibitor, Improves Quality of Life in Patients with Cold Agglutinin Disease : Patient-Reported Outcomes Results of the Phase 3 Cardinal Study
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. S3: 48th Congress of the Italian Society of Hematology, 24-27 October 2021, Abstract Book, S. 111 - 112
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, A.M.; Röth, Alexander; Soret, J.; Frieri, C.; Sicre de Fontbrune, F.; Marano, L.; Alashkar, Ferras; Benajiba, L.; Marotta, S.; Rozenberg, I.; Milojevic, J.; End, P.; Nidamarthy, P.K.; Junge, G.; Peffault de Latour, R.;
    The Oral Complement Factor B Inhibitor Iptacopan is Safe and Effective in Improving Hematological Response in Paroxysmal Nocturnal Hemoglobinuria Patients with Poor Response to Eculizumab, even in Monotherapy
    48th Congress of the Italian Society of Hematology, 24-27 October 2021, Milan, Italy,
    In: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. 10, S3: 48th Congress of the Italian Society of Hematology, 24-27 October 2021, S. 106 - 107
    Online Volltext: dx.doi.org/ (Open Access)
  • Ferreri, Andrés J M; Cwynarski, Kate; Pulczynski, Elisa; Fox, Christopher P.; La Rosée, Paul; Schorb, Elisabeth; Krampera, Mauro; Ilariucci, Fiorella; Orsucci, Lorella; Fabbri, Alberto; Tucci, Alessandra; Röth, Alexander; Linton, Kim; Binder, Mascha; Hemmaway, Claire; Cabras, Maria Giuseppina; Pinto, Antonio; Calimeri, Teresa; Cavalli, Franco; Zucca, Emanuele; Illerhaus, Gerald;
    Treatment of Patients with Relapsed or Refractory Primary CNS Lymphoma (rrPCNSL) Enrolled in the Randomized Trials of the International Extranodal Lymphoma Study Group (IELSG)
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 1417 - 1419
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin G.; Risitano, Antonio; Röth, Alexander; He, Guangsheng; Pu, Jeffrey; Wright, Lilyan; Appius, Anita; Sostelly, Alexandre; Sreckovic, Sasha; Stanzel, Sven F.; Munir, Talha; Nishimura, Jun-Ichi;
    Two Currently Recruiting Randomized Phase III Trials : COMMODORE 1 and 2 Evaluating Crovalimab Vs Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria with or without Current Anti-Complement Therapy
    63rd ASH Annual Meeting and Exposition, 11-14 December 2021, Atlanta,
    In: Blood Jg. 138 (2021) Nr. Supplement 1: 63rd ASH Annual Meeting Abstracts, S. 4313 - 4315
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Jäger, U.; Jilma, B.; Barcellini, W.; Hill, A.; Hill, Q.; Kuter, D. J.; Broome, C. M.; Michel, M.; Zeerleder, S. S.; Ueda, Y.; Morales Arias, J.; Su, J.; Berentsen, S.;
    Cold Agglutinin Disease (CAD) Real World Evidence (CADENCE) registry : Design of the first international, prospective CAD registry
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 180
    Online Volltext: dx.doi.org/ (Open Access)
  • Sayer, Herbert Gottfried; Witzens-Harig, Mathias; Wattad, Mohammad; Korfel, Agnieszka; Hilgendorf, Inken; Franke, Georg-Nikolaus; Illerhaus, Gerald; Heinsch, Michael; Metzner, Bernd; Zinngrebe, Eva Bettina; Binder, Mascha; Ringhoffer, Mark; Röth, Alexander; Geer, Thomas; Schmidt, Volker; Dreger, Peter;
    Final Results of a Prospective, Multicenter, noninterventional Study on thiotepa-based Autologous Hematopoietic Cell Transplantation (ASCT) for CNS or non-CNS Lymphoma
    46th Annual Meeting of the European Society for Blood and Marrow Transplantation ; 29 August - 1 September, 2020, Virtual Meeting,
    In: Bone Marrow Transplantation Jg. 55 (2020) Nr. Suppl. 1, S. 298
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, Antonio M.; Röth, Alexander; Soret, Juliette; Frieri, Camilla; Sicre de Fontbrune, Flore; Marano, Luana; Rozenberg, Izabella; Milojevic, Julie; End, Peter; Nidamarthy, Prasanna K.; Junge, Guido; Peffault de Latour, Regis;
    LNP023-A New Oral Complement Factor-B Inhibitor Normalizes Hemoglobin in Paroxysmal Nocturnal Hemoglobinuria Patients with Poor Response to Eculizumab, Both as Add-on and Monotherapy
    46th Annual Meeting of the European Society for Blood and Marrow Transplantation ; 29 August - 1 September, 2020, Virtual Meeting,
    In: Bone Marrow Transplantation Jg. 55 (2020) Nr. Suppl. 1, S. 32 - 33
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Barcellini, W.; D Sa, S.; Miyakawa, Y.; Broome, C. M.; Michel, M.; Kuter, D. J.; Jilma, B.; Anderson Tvedt, T. H.; Lin, S.; Jiang, X.; Reuter, C.; Hobbs, W.; Berentsen, S.;
    Results from the phase 3 Cardinal study part A : Inhibition of complement C1s with Sutimlimab in patients with Cold Agglutinin Disease (CAD)
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 177
    Online Volltext: dx.doi.org/ (Open Access)
  • Castro, Carlos de; Hillmen, Peter; Szer, Jeff; Weitz, Ilene; Röth, Alexander; Hoechsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; Nishimori, Hisakazu; Tan, Lisa; Hamdani, Mohamed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio; Latour, Regis Peffault de;
    Results of the PEGASUS Phase 3 Randomized Trial Demonstrating Superiority of the C3 Inhibitor, Pegcetacoplan, Compared to Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria
    SOHO 2020, 8th annual meeting of the Society of Hematologic Oncology (virtual event), 9-12 September 2020, Houston,
    In: Clinical Lymphoma, Myeloma & Leukemia Jg. 20 (2020) Nr. Supplement 1, Proceedings of the Society of Hematologic Oncology 2020 Annual Meeting, S. S216 - S217
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Hillmen, P.; Szer, J.; Weitz, I.; Höchsmann, B.; Panse, J.; Schafhausen, P.; Usuki, K.; Griffin, M.; Kiladjian, J.-J.; Castro, C. de; Nishimori, H.; Tan, L.; Hamdani, M.; Deschatelets, P.; Francois, C.; Grossi, F.; Risitano, A.; Peffault de Latour, R.;
    Results of the PEGASUS phase 3 randomized trial demonstrating superiority of the C3 inhibitor, pegcetacoplan, compared to eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH)
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 176
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander
    Results of the pegasus phase III trial for the comparison of pegcetacoplan with eculizumab in patients with paroxysmal nocturnal hemoglobinuria
    In: Haematologica / The Hematology Journal Jg. 105 (2020) Nr. Suppl. 3, S. 110
  • Proske, P.; Aramayo-Singelmann, Carmen; Reinhardt, Dirk; Koldehoff, Michael; Reinhardt, Hans Christian; Röth, Alexander; Alashkar, Ferras;
    Sickle Cell Disease (SCD) : a single-centre experience - update
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 180 - 181
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Carpinteiro, Alexander; Bauer, Sebastian; Hüttmann, Andreas; Dührsen, Ulrich; Reinhardt, Hans Christian; Röth, Alexander;
    Think twice : Anemia of chronic disease (ACD) due to angiomatoid fibrous histiocytoma (AFH)
    Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,
    In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 181
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, A.; Röth, Alexander; Hill, A.; Charbonnier, A.; Schouten, H. C.; Khaled, S.; Gutierrez, E. O.; Ogawa, M.; Yu, J.; Rottinghaus, S.; Ishiyama, K.; Kulasekararaj, A.;
    A phase 3 study of Ravulizumab (ALXN1210) vs. Eculizumab in adults with paroxysmal nocturnal hemoglobinuria currently treated with Eculizumab : subgroup analysis by transfusion history and demographics
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Supplement 4: Abstracts, S. 302
    Online Volltext: dx.doi.org/ (Open Access)
  • Sostelly, Alexandre; Soubret, Antoine; Bucher, Christoph; Buatois, Simon; Charoin, Jean-Eric; Jordan, Gregor; Klughammer, Barbara; Dieckmann, Andreas; Fukuzawa, Taku; Gotanda, Keisuke; Shinomiya, Kenji; Yoon, Sung-Soo; Panse, Jens P.; Nishimura, Junichi; Röth, Alexander; Nagy, Zsolt; Peffault de Latour, Régis;
    Characterizing C5 Inhibition with the SMART-Ig Anti-hC5 Antibody Crovalimab in PNH Patients Using Free Available Paratopes
    61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood Jg. 134 (2019) Nr. Supplement_1, S. 1227 - 1227
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Haverkamp, Tobias; Finckh, Ulrich; Göthert, Joachim Rudolf; Dührsen, U.; Röth, Alexander;
    Clonal evolution in eltrombopag-resistant aplastic anemia indicated by a novel mutation in transcripts of the thrombopoietin-receptor MPL : a case report
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Supplement 4: Abstracts, S. 147 - 148
    Online Volltext: dx.doi.org/ (Open Access)
  • Sostelly, Alexandre; Buatois, Simon; Soubret, Antoine; Winter, Erica; Klughammer, Barbara; Hsu, Joy C.; Jordan, Gregor; Bucher, Christoph; Charoin, Jean-Eric; Gotanda, Keisuke; Shinomiya, Kenji; Nagy, Zsolt; Panse, Jens P.; Yoon, Sung-Soo; Peffault de Latour, Régis; Nishimura, Junichi; Röth, Alexander;
    Exposure-Response Relationship of the SMART-Ig Anti-hC5 Antibody Crovalimab (SKY59): Results from the Umbrella Phase 1/2 Composer Trial in Healthy Volunteers and PNH Patients
    61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood Jg. 134 (2019) Nr. Supplement_1: 61st ASH Annual Meeting, S. 3745 - 3745
    Online Volltext: dx.doi.org/ (Open Access)
  • Broome, Catherine M; Röth, Alexander; Kuter, David J.; Scully, Marie; Smith, Roy; Wang, Jennifer; Reuter, Caroline; Hobbs, William;
    Inhibition of the Classical Pathway of Complement with Sutimlimab in Chronic Immune Thrombocytopenic Purpura Patients without Adequate Response to Two or More Prior Therapies
    61st ASH Annual Meeting and Exposition, 07.-10.12.2019, Orlando, FL,
    In: Blood Jg. 134 (2019) Nr. Supplement_1, S. 898 - 898
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin; Hill, Anita; Langemeijer, Saskia; Wells, Richard A.; Gonzalez-Fernandez, F. Ataulfo; Gaya, Anna; Ojeda Gutierrez, Emilio; Piatek, Caroline I.; Mitchell, Lindsay D; Usuki, Kensuke; Bosi, Alberto; Brodsky, Robert A.; Ogawa, Masayo; Yu, Ji; Ortiz, Stephan; Röth, Alexander; Lee, Jong-Wook; Peffault de Latour, Régis;
    One-Year Efficacy and Safety from a Phase 3 Trial of Ravulizumab in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Receiving Prior Eculizumab Treatment
    Konferenz 61st ASH (American Society of Hematology) Annual Meeting & Exposition; Dec 07 - 10 2019; Orlando, USA,
    In: Blood Jg. 134 (2019) Nr. Supplement_1, S. 2231 - 2231
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Fryzek, J.; Jiang, X.; Reichert, H.; Morales, J.; Broome, C. M.;
    Seasonal patterns of anemia, hemolytic markers, healthcare resource utilization, and thromboembolic events in cold agglutinin disease
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Supplement 4: Abstracts, S. 9
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Nagy, Z.; Gaàl-Weisinger, J.; Peffault de Latour, R.; Panse, J.; Yoon, S. S.; Egyed, M.; Ichikawa, S.; Ito, Y.; Seok Kim, S.; Schrezenmeier, H.; Höchsmann, B.; Körper, S.; Sica, S.; Usuki, K.; Sostelly, A.; Higginson, J.; Dieckmann, A.; Anzures-Caberas, J.; Shinomiya, K.; Klughammer, B.; Jahreis, A.; Bucher, C.; Nishimura, J. I.;
    Subcutaneous Crovalimab (SKY59) for PNH : COMPOSER long term follow-up
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Supplement 4: Abstracts, S. 245
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Risitano, A.; Jang, J. H.; Lee, G.-W.; Wanachiwanawin, W.; Schrezenmeier, H.; Yonemura, Y.; Munir, T.; Pavani, R.; Aguzzi, R.; Shafner, L.; Kulagin, A.; Sicre de Fontbrune, F.;
    Transfusion requirements in adult patients with paroxysmal nocturnal hemoglobinuria naive to complement inhibitors receiving Ravulizumab or Eculizumab : results from a phase 3 non-inferiority study
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 11. - 14. Oktober 2019, Berlin, Germany,
    In: Oncology Research and Treatment Jg. 42 (2019) Nr. Supplement 4: Abstracts, S. 97
    Online Volltext: dx.doi.org/ (Open Access)
  • Struve, C.; Alashkar, Ferras; Baum, J.; Noppeney, Richard; Dührsen, U.; Röth, Alexander;
    Antithymocyte Globulin (ATG), CSA and eltrombopag followed by autologous stem cell transplantation in a patient with Very Severe Aplastic Anemia (vSAA) and life-threatening pneumonia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 105
    Online Volltext: dx.doi.org/ (Open Access)
  • Beier, F.; Kirschner, M.; Bouillon, A.-S.; Halfmeyer, I.; Ventura Ferreira, M.; Kricheldorf, K.; Maurer, A.; Wilop, S.; Thol, F.; Röth, Alexander; Platzbecker, U.; Radsak, M.; Ayuk, Francis A.; Corbacioglu, Selim; Höchsmann, B.; Wilk, C. M.; Hinze, C.; Chromik, J.; Egle, Alexander; Bittenbring, J. T.; Eggermann, T.; Kurth, I.; Koschmieder, S.; Schemionek, M.; Isfort, S.; Panse, J.; Brümmendorf, T. H.;
    Identification of patients with classical and/or cryptic dyskeratosis congenita (DKC) by telomere length screening using different percentiles : results from the Aachen telomeropathy registry
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 126 - 127
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Dampmann, M.; Herich-Terhürne, D.; Chapot, le Saout, Valerie; Dührsen, Ulrich; Rottinghaus, S. T.; Röth, Alexander;
    Meningococcal-Septicemia and its resolution in a patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) receiving ALXN1210, a complement C5 inhibitor
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 198
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Rottinghaus, S. T.; Hill, A.; Kim, J. S.; Schrezenmeier, H.; Terriou, L.; Urbano-Ispizua, A.; Wells, R. A.; Jang, J. H.; Szer, J.; Aguzzi, R.; Bachman, E. S.; Damokosh, A. I.; Shafner, L.; Lee, J.-W.;
    Optimization of dose regimen for ALXN1210, a novel complement C5 inhibitor, in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) : results of 2 phase 1/2 studies
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 128
    Online Volltext: dx.doi.org/ (Open Access)
  • Kulasekararaj, Austin G.; Hill, Anita; Rottinghaus, Scott T.; Langemeijer, Saskia; Wells, Richard A.; Gonzalez-Fernandez, F. Ataulfo; Gaya, Anna; Lee, Jong-Wook; Ojeda Gutierrez, Emilio; Piatek, Caroline I.; Szer, Jeffrey; Risitano, Antonio M.; Nakao, Shinji; Bachman, Eric; Shafner, Lori; Damokosh, Andrew I.; Ortiz, Stephan; Röth, Alexander; Peffault De Latour, Regis;
    Results from a Phase 3, Multicenter, Non-Inferiority Study of Ravulizumab (ALXN1210) Versus Eculizumab in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Currently Treated with Eculizumab
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood Jg. 132 (2018) Nr. Supplement 1, S. 625 - 625
    Online Volltext: dx.doi.org/ (Open Access)
  • Cario, Holger; Schwarz, M.; Röth, Alexander; Tartaglione, I.; Gamberini, R.; Voskaridou, E.; Ricchi, Paolo; Pietrangelo, A.; Zhang, X.; Laadem, A.; Sherman, M. L.; Linde, P. G.; Piga, A.;
    Results of a phase 2 study as a rationale for the BELIEVE study, a phase 3, double-blind, randomized, placebo-controlled, multicenter study to determine the efficacy and safety of luspatercept in adult patients (Pts) requiring regular RBC transfusions due to β-Thalassemia (β-Thal)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 128 - 129
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Fryzek, Jon; Jiang, Xiaohui; Morales, Jaime; Broome, Catherine M.;
    Seasonal Patterns of Anemia, Hemolytic Markers and Healthcare Resource Utilization Among Patients with Cold Agglutinin Disease in the United States : A Retrospective Analysis
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood Jg. 132 (2018) Nr. Supplement 1, S. 4873 - 4873
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Herich-Terhuerne, Doerte; Preising, Nicole; Duehrsen, Ulrich; Ulrich, Vogel; Röth, Alexander;
    Serologic Response to Meningococcal Vaccination in Patients with Cold Agglutinin Disease (CAD) in the New Era of Complement Inhibition
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood Jg. 132 (2018) Nr. Supplement 1, S. 3817 - 3817
    Online Volltext: dx.doi.org/ (Open Access)
  • Drießen, M. N.; Röth, Alexander; Distelmaier, L.; Wagner, M.; Lenz, V.; Pentek, F.; Liebregts, Tobias; Dührsen, U.; Alashkar, Ferras;
    Sickle Cell Disease (SCD) : A single-centre experience
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 196 - 197
    Online Volltext: dx.doi.org/ (Open Access)
  • Versmold, K.; Tsagakis, Konstantinos; Alashkar, Ferras; Herich-Terhürne, D.; Dührsen, Ulrich; Röth, Alexander;
    Subacute aortic dissection in a patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) on chronic treatment with eculizumab
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 199
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Egyed, Miklos; Ichikawa, Satochi; Kim, Jin Seok; Nagy, Zsolt; Gaàl Weisinger, Julia; Panse, Jens P.; Peffault De Latour, Regis; Sicre De Fontbrune, Flore; Sica, Simona; Usuki, Kensuke; Yoon, Sung-Soo; Winter, Erica; Hsu, Joy C.; Dieckmann, Andreas; Anzures-Cabrera, Judith; Jordan, Gregor; Shinomiya, Kenji; Klughammer, Barbara; Bucher, Christoph; Jahreis, Angelika; Nishimura, Jun-Ichi
    The SMART Anti-hC5 Antibody (SKY59/RO7112689) Shows Good Safety and Efficacy in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)
    In: Blood Jg. 132 (2018) Nr. Supplement 1: 60th ASH Annual Meeting Abstracts, S. 535 - 535
    Online Volltext: dx.doi.org/ (Open Access)
  • Sayer, Herbert G.; Witzens-Harig, Mathias; Wattad, Mohammed; Korfel, Agnieszka; Hilgendorf, Inken; Franke, Georg-Nikolaus; Illerhaus, Gerald; Heinsch, Michael; Metzner, Bernd; Zinngrebe, Eva Bettina; Basara, Nadezda; Binder, Mascha; Schmidt, Volker; Ringhoffer, Mark; Röth, Alexander; Geer, Thomas; Dreger, Peter;
    Thiotepa-based Autologous hematopoietic stem cell transplantation (ASCT) for CNS or non-CNS lymphoma : first results of a prospective, multicenter, non-interventional study
    The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation; Mar 18 - 21, 2018; Lisboa, Portugal,
    In: Bone Marrow Transplantation Jg. 53 (2018) Nr. Supplement, S. 108 - 109
    Online Volltext
  • Alashkar, Ferras; Kloke, O.; Dührsen, Ulrich; Röth, Alexander;
    Thrombotic storm leading to the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 199 - 200
    Online Volltext: dx.doi.org/ (Open Access)
  • Alashkar, Ferras; Drießen, M. N.; Wagner, M.; Lenz, V.; Klump, Hannes; Pentek, F.; Baum, J.; Röth, Alexander; Dührsen, Ulrich; Liebregts, Tobias;
    Veno-venous Extracorporal Membrane Oxygenation (VV-ECMO) in a female patient with Sickle Cell Disease (SCD) and Fulminat Acute Chest Syndrome (ACS) : A case report
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,
    In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 198
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Dirkmann, Daniel; Lenz, V.; Heinrichs, Stefan; Fuchs, Norbert; Breyer, M.; Dührsen, Ulrich; Peters, Jürgen; Horn, Peter
    Eculizumab rescue therapy in ABO-incompatible red blood cell transfusion : a case report
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 138 - 139
  • Korfel, Agnieszka; Thiel, Eckhard; Martus, Peter; Möhle, Robert; Griesinger, Frank; Rauch, Michael; Röth, Alexander; Hertenstein, Bernd; Fischer, Thomas; Hundsberger, Thomas; Mergenthaler, Hans-Günther; Junghanss, Christian; Birnbaum, Tobias; Fischer, Lars; Jahnke, Kristoph; Herrlinger, Ulrich; Plasswilm, Ludwig; Naegele, Thomas; Pietsch, Torsten; Weller, Michael
    G-PCNSL-SG-1 randomized phase III trial of high-dose methotrexate with or without whole brain radiotherapy for primary central nervous system lymphoma : Long-term follow-up
    In: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15, suppl., S. 8527
    Online Volltext: dx.doi.org/
  • Fischer, L.; Hanel, M.; Mohle, R.; Schroers, R.; Elter, T.; Reiser, M.; Dreyling, M.; Illerhaus, G.; Eucker, J.; Scholz, C.; Metzner, B.; Röth, Alexander; Birkmann, J.; Schlegel, U.; Martus, P.; Thiel, E.; Agnieszka, K.;
    First results of a phase II study with combined systemic and intrathecal chemotherapy followed by high-dose chemotherapy for CNS relapse of aggressive lymphomas
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 192
    Online Volltext: dx.doi.org/
  • Korfel, A.; Fischer, L.; Martus, P.; Mohle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Leithauser, M.; Mergenthaler, H. G.; Herrlinger, U.; Weller, M.; Thiel, E.;
    Impact of Meningeal Dissemination (MD) on outcome in primary CNS Lymphoma in the G-PCNSL-SG1 Trial
    11th International Conference on Malignant Lymphoma 15-18 June 2011, Lugano (Switzerland),
    In: Annals of Oncology Jg. 22 (2011) Nr. Suppl. 4, S. iv92
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Tokareva, O.; Hock, C.; Dührsen, Ulrich;
    Management of pregnancy in paroxysmal nocturnal hemoglobinuria (PNH) in the era of eculizumab : A case report and updated review
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 67
    Online Volltext: dx.doi.org/
  • Janson, D.; Fiedler, Melanie; Horacek, Michael; Katsounas, Antonios; Roggendorf, Michael; Dührsen, Ulrich; Röth, Alexander;
    Outbreak - pandemic 2009 influenza A (H1N1) infections in a hematology ward : Clinical presentation and outcome
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 43
    Online Volltext: dx.doi.org/
  • Jahnke, K.; Martus, P.; Lokka, S.; Mohle, R.; Griesinger, F.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H. G.; Leithauser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Florschutz, A.; Fischer, L.; Weller, M.; Thiel, E.; Korfel, A.;
    Prognostic factors and score for response and survival in primary central nervous system lymphoma from a randomized phase III trial
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 296 - 296
    Online Volltext: dx.doi.org/
  • Jahnke, K.; Martus, P.; Rose, T.; Fischer, L.; Mohle, R.; Klasen, H. A.; Rauch, M.; Röth, Alexander; Hertenstein, B.; Fischer, T.; Hundsberger, T.; Mergenthaler, H. G.; Leithauser, M.; Birnbaum, T.; Herrlinger, U.; Schubert, J.; Birkmann, J.; Weller, M.; Thiel, E.; Korfel, A.;
    Prognostic factors and scores for chemotherapy-related toxicity in primary central nervous system lymphoma (PCNSL) treated with high-dose methotrexate (HDMTX) with or without ifosfamide : results from a randomized phase III trial
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 295 - 296
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Hock, C.; Tokareva, O.; Konik, A.; Dührsen, Ulrich;
    Role of bone marrow failure in paroxysmal nocturnal hemoglobinuria (PNH) patients chronically treated with Eculizumab
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 115
    Online Volltext: dx.doi.org/
  • Röth, Alexander; Hüttmann, Andreas; Dührsen, Ulrich;
    DECADE Trial : Inhibition of theterminal complement system using the anti-C5 antibody eculizumab for the treatment of cold agglutinin disease (CAD)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 112
    Online Volltext: dx.doi.org/
  • Gothert, Joachim Rudolf; Eisele, Lewin; Klein-Hitpaß, Ludger; Weber, Stefanie; Fuhrer, Anja; Sellmann, Ludger; Röth, Alexander; Dührsen, Ulrich; Pircher, Hanspeter; Dürig, Jan
    Expanded CLL CD8(+) T-Cells Are Driven Into a Senescent KLRG1(+) Effector Memory Phenotype
    In: Blood Jg. 116 (2010) Nr. 21, S. 403
  • Konik, A.; Dührsen, Ulrich; Röth, Alexander;
    Nodular lesions of the scalp and a mediastinal mass in T-cell acute lymphoblastic leukemia (T-ALL)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 238
    Online Volltext: dx.doi.org/
  • Röth, Alexander; de Beer, D.; Porret, N.; Leibundgut, O. E.; Dührsen, Ulrich; Baerlocher, G.;
    Telomere length measurement by automated multicolor flow-FISH identifies patients with an inherited Bone Marrow Failure (BMF)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 48 - 49
    Online Volltext: dx.doi.org/

    • Beiträge in Sammelwerken und Tagungsbänden

  • Röth, Alexander; Baerlocher, Gabriela M.; Harley, Calvin B.
    Imetelstat (GRN163L) - Telomerase-Based Cancer Therapy
    In: Recent Results in Cancer Research / Schlag, Peter M.; Senn, Hans-Jörg (Hrsg.) 2010, S. 221 - 234
    Online Volltext: dx.doi.org/

    • Bücher/Sammelwerke/Tagungsbände

  • Röth, Alexander
    Telomere und Telomerase bei physiologischen und pathologischen Zuständen des hämatopoietischen Systems
    Duisburg, Essen (2011) 1 CD-ROM

    • Poster / Posterbeiträge

  • D'Sa, Shirley; Vos, Josephine M.I.; Barcellini, Wilma; Wardęcki, Marek; Perrin, Laurent; Barker, Graham; Zilberstein, Moshe; Storek, Michael; Chow, Timothy; Röth, Alexander;
    Classical Complement Inhibition By SAR445088 (BIVV020) in Adults with Cold Agglutinin Disease : Safety, Tolerability and Activity Results from the Open-Label, Non-Randomized, Single-Dose Phase 1b Study
    65th ASH Annual Meeting, December 9-12, 2023, San Diego, CA, USA,
    In: Blood Jg. 142 (2023) Nr. Supplement 1, S. 1069 - 1071
    Online Volltext: dx.doi.org/ (Open Access)
  • Poppenborg, Friederike; Pöttgen, Christoph; Möller-Hartmann, Claudia; Schneider, Artur; Reinhardt, H. Christian; Röth, Alexander; Alashkar, Ferras;
    Intraspinal extramedullary hematopoietic mass (EMH) in a luspatercept-treated patient with transfusion-dependent beta-thalassemia (TDT)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DHGO Abstracts, S. 299 - 300
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Kuter, D.; Piatek, C.; Dummer, W.;
    Phase 3, Randomized, Double-Blind, Placebo-Controlled, Global Study (FORWARD) of Fostamatinib for the Treatment of Warm Antibody Autoimmune Hemolytic Anemia
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 295
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Broome, C. M.; Barcellini, W.; Weitz, I. C.; et al.;
    Sutimlimab provides sustained improvements in patient-reported outcomes and quality of life in patients with cold agglutinin disease : open-label extension of the randomized, Phase 3 CADENZA Study
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 297
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Scheinberg, P.; Villa Cle, D.; Kulasekararaj, A.; et al.;
    The phase III randomized, multicenter commodore 1 trial : comparison of crovalimab vs eculizumab in complement inhibitor-experienced patients with paroxysmal nocturnal hemoglobinuria (PNH)
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 200 - 201
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; He, G.; Brodsky, A.; Han, B.; et al.;
    The phase III, randomized, multicenter commodore 2 trial : results from the study of crovalimab vs eculizumab in paroxysmal nocturnal hemoglobinuria (PNH) patients naive to complement inhibitors
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,
    In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 294 - 295
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Dingli, D.; Mahajerin, A.; Savage, J.; Al-Adhami, M.; Yeh, M.; Birhiray, R.;
    Analyse der Persistenz der Anämie und damit verbundener unerwünschter Ereignisse bei Patienten mit paroxysmaler nächtlicher Hämoglobinurie, die mit Pegcetacoplan behandelt wurden
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 7.–10. Oktober 2022, Wien, Austria,
    In: Oncology Research and Treatment Jg. 45 (2022) Nr. Supplement 2, S. 233
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, Antonio; Peffault de Latour, Régis; Yap, Eng Soo; Wong, Lily LL; Ko, Bor-Sheng; Yoon, Sung-Soo; Roeth, Alexander; Baltcheva, Irina; Milojevic, Julie; Fagan, Niamh; Kulmatycki, Kenneth; Nidamarthy, Prasanna K; Junge, Guido; Jang, Jun Ho;
    Dose-Exposure-Response Relationships of Biomarkers and Efficacy Measures with Iptacopan, a Complement Factor B Inhibitor, in Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) with or without Concomitant Anti-C5 Therapy
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 5803 - 5804
    Online Volltext: dx.doi.org/ (Open Access)
  • Patriquin, Christopher J.; Bogdanovic, Andrija; Griffin, Morag; Kelly, Richard; Maciejewski, Jaroslaw P.; Mulherin, Brian; Peffault de Latour, Régis; Roeth, Alexander; Selvaratnam, Veena; Szer, Jeffrey; Savage, Jessica; Horneff, Regina; Tan, Lisa; Yeh, Michael; Panse, Jens;
    Long-Term Safety and Efficacy of Pegcetacoplan Treatment in Adults with Paroxysmal Nocturnal Hemoglobinuria
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 2921 - 2923
    Online Volltext: dx.doi.org/ (Open Access)
  • Roeth, Alexander; Berentsen, Sigbjørn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M.I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Wang, Jennifer; Vagge, Deepthi; Wardecki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M.;
    Sustained Complement C1s Inhibition with Sutimlimab in Patients with Cold Agglutinin Disease Results in Continued Efficacy during Part B of the Randomized Placebo-Controlled Phase 3 Cadenza Study (NCT03347422)
    64th Annual Meeting and Exposition of the American Society of Hematology ; December 10 - 13, 2022, New Orleans, LA, USA,
    In: Blood Jg. 140 (2022) Nr. Supplement 1, S. 2825 - 2827
    Online Volltext: dx.doi.org/ (Open Access)
  • Blandino, Peter; de Latour, Régis Peffault; Szer, Jeffrey; Ilene, Weitz; Röth, Alexander; Höchsmann, Britta; Panse, Jens; Usuki, Kensuke; Griffin, Morag; Kiladjian, Jean-Jacques; de Castro, Carlos; Nishimori, Hisakazu; Tan, Lisa; Al-Adhami, Mohammed; Deschatelets, Pascal; Francois, Cedric; Grossi, Federico; Risitano, Antonio; Hillmen, Peter;
    Forty-Eight Week Efficacy and Safety of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria and Suboptimal Response to Prior Eculizumab Treatment
    Society for the Advancement of Patient Blood Management 2021 Annual Meeting PBM Rocks! Virtual Meeting,
    In: Anesthesia & Analgesia Jg. 133 (2021) Nr. 3S, S. 6 - 7
    Online Volltext (Open Access)
  • Röth, Alexander; Peffault de Latour, R.; Szer, J.; Weitz, I.; Höchsmann, B.; Panse, J.; Usuki, K.; Griffin, M.; Kiladijan, J.-J.; De Castro, C. M.; Nishimori, H.; Tan, L.; Al-Adhami, M.; Deschatelets, P.; Francois, C.; Grossi, F.; Risitano, A.; Hillmen, P.;
    Forty-eight week efficacy and safety of pegcetacoplan in adult patients with paroxysmal nocturnal hemoglobinuria and suboptimal response to prior eculizumab treatment
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 169
    Online Volltext: dx.doi.org/ (Open Access)
  • Röth, Alexander; Lenderking, William R.; Sarda, Sujata P.; Baver, Scott B.; Hamdani, Mohamed; Hsieh, Ray; Shaffer, Shannon; Yeh, Michael; Cella, David
    Improvements in Fatigue and Physical Function Evaluated Through Changes in Clinical Outcomes in Paroxysmal Nocturnal Hemoglobinuria : Post-Hoc Analyses from the PEGASUS Study
    In: British Journal of Haematology Jg. 193 (2021) Nr. S1, S. 77 - 232
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Röth, Alexander; Barcellini, W.; D’Sa, S.; Miyakawa, Y.; Broome, C.; Michel, M.; Kuter, D.; Jilma, B.; Tvedt, T. H. A.; Weitz, I. C.; Patel, P.; Jiang, X.; Reuter, C.; Su, J.; Shafer, F.; Lee, M.; Hobbs, W.; Berentsen, S.;
    Interim results of the phase 3 CARDINAL study long-term follow-up: Inhibition of complement C1s with sutimlimab in patients with Cold Agglutinin Disease (CAD)
    Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,
    In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 169 - 170
    Online Volltext: dx.doi.org/ (Open Access)
  • Risitano, A.; Munir, T.; Jang, J. Ho; Lee, G.-W.; Wanachiwanawin, W.; Schrezenmeier, H.; Yonemura, Y.; Pavani, R.; Wang, J.; Kulagin, A.; Kulasekararaj, A.; de Fontbrune, F. Sicre; Röth, Alexander;
    Transfusion requirements in adult patients with paroxysmal nocturnal hemoglobinuria with or without a history of bone marrow disorder receiving ravulizumab and eculizumab : results from a phase 3 non-inferiority study extension
    61st Annual Scientific Meeting of the British Society for Haematology, 25–28 April 2021, Virtual,
    In: British Journal of Haematology Jg. 193 (2021) Nr. S1, S. 203 - 204
    Online Volltext: dx.doi.org/ (Open Access)