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Biologie, ZMB
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45117 Essen
45117 Essen
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Universitätsprofessor/in, Mikrobiologie II
Aktuelle Veranstaltungen
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2023 SS
Vergangene Veranstaltungen (max. 10)
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2022 WS
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
- Allgemeine Methoden (Bachelor Bio)
- Anleitung zum wissenschafltichen Arbeiten
- Einführung in die Medizinische Biologie
- Aktuelle Forschung in der Mikrobiologie
- Übungen zur Mikrobiologie und Genetik für medizinische Biologen
- ZJD91025 Einführung in die Medizinische Biologie
- ZJA40320 WP Mikrobio. u. chem. Bio
- ZJA40510 Einführung in die Mikrobiol.
- Molekulare Mikrobiologie und chemische Biologie (5.Sem. MedBio/Bio)
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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10q26 – The enigma in age-related macular degenerationIn: Progress in Retinal and Eye Research (2022) in pressISSN: 1873-1635; 1350-9462Online Volltext: dx.doi.org/ (Open Access)
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An allosteric HTRA1-calpain 2 complex with restricted activation profileIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 119 (2022) Nr. 14,ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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PPI-Affinity : A Web Tool for the Prediction and Optimization of Protein-Peptide and Protein-Protein Binding AffinityIn: Journal of Proteome Research Jg. 21 (2022) Nr. 8, S. 1829 - 1841ISSN: 1535-3907; 1535-3893Online Volltext: dx.doi.org/ (Open Access)
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Persister state-directed transitioning and vulnerability in melanomaIn: Nature Communications Jg. 13 (2022) Nr. 1,ISSN: 2041-1723Online Volltext: dx.doi.org/ (Open Access)
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Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensitiesIn: Brain: A Journal of Neurology Jg. 144 (2021) Nr. 9, S. 2670 - 2682ISSN: 0006-8950; 1460-2156Online Volltext: dx.doi.org/ (Open Access)
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Activation by substoichiometric inhibitionIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 117 (2020) Nr. 3, S. 1414 - 1418ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σIn: ACS Chemical Biology Jg. 15 (2020) Nr. 1, S. 262 - 271ISSN: 1554-8937; 1554-8929Online Volltext: dx.doi.org/ (Open Access)
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From dolastatin 13 to cyanopeptolins, micropeptins, and lyngbyastatins : the chemical biology of Ahp-cyclodepsipeptidesIn: Natural Product Reports Jg. 37 (2020) Nr. 2, S. 163 - 174ISSN: 0265-0568; 1460-4752Online Volltext: dx.doi.org/
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Supramolecular Mechanism of Viral Envelope Disruption by Molecular TweezersIn: Journal of the American Chemical Society: JACS Jg. 142 (2020) Nr. 40, S. 17024 - 17038ISSN: 0002-7863; 1520-5126Online Volltext: dx.doi.org/ (Open Access)
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Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of ActionIn: ChemMedChem Jg. 14 (2019) Nr. 11, S. 1074 - 1078ISSN: 1860-7187; 1860-7179Online Volltext: dx.doi.org/
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Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly ModulatorIn: Journal of the American Society for Mass Spectrometry Jg. 30 (2019) Nr. 1, S. 16 - 23ISSN: 1879-1123; 1044-0305Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damageIn: EMBO Reports (2019) S. e48014ISSN: 1469-3178; 1469-221XOnline Volltext: dx.doi.org/ (Open Access)
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HTRA1-Dependent Cell Cycle ProteomicsIn: Journal of Proteome Research Jg. 17 (2018) Nr. 8, S. 2679 - 2694ISSN: 1535-3907; 1535-3893Online Volltext: dx.doi.org/
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Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent ProbesIn: ACS Chemical Biology Jg. 13 (2018) Nr. 5, S. 1307 - 1312ISSN: 1554-8937; 1554-8929Online Volltext: dx.doi.org/
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Identification of the Natural Product RotihibinA as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional ProfilingIn: Chemistry - A European Journal Jg. 24 (2018) Nr. 48, S. 12500 - 12504ISSN: 0947-6539; 1521-3765Online Volltext: dx.doi.org/
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Inactivation of the serine protease HTRA1 inhibits tumor growth by deregulating angiogenesisIn: Oncogene Jg. 37 (2018) S. 4260 - 4272ISSN: 1476-5594; 0950-9232Online Volltext: dx.doi.org/
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Utilities for Mass Spectrometry Analysis of Proteins (UMSAP) : Fast post-processing of mass spectrometry dataIn: Rapid Communications in Mass Spectrometry Jg. 32 (2018) Nr. 19, S. 1659 - 1667ISSN: 1097-0231; 0951-4198Online Volltext: dx.doi.org/
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Small Molecules from Deep within the GutIn: ChemBioChem Jg. 18 (2017) Nr. 11, S. 967 - 968ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/
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Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease InhibitorsIn: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 29, Special Issue: 100th Anniversary of the Royal Australian Chemical Institute, S. 8555 - 8558ISSN: 1521-3773; 1433-7851; 0570-0833Online Volltext: dx.doi.org/
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Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactionsIn: Nature Communications Jg. 8 (2017) S. 14472ISSN: 2041-1723Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticlesIn: Beilstein Journal of Nanotechnology Jg. 8 (2017) Nr. 1, S. 381 - 393ISSN: 2190-4286Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagyIn: The EMBO Journal Jg. 36 (2017) Nr. 2, S. 135 - 150ISSN: 0261-4189; 1460-2075Online Volltext: dx.doi.org/ (Open Access)
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Epigenetic silencing of serine protease HTRA1 drives polyploidyIn: BMC Cancer Jg. 16 (2016) Nr. 1,ISSN: 1471-2407Online Volltext: dx.doi.org/ (Open Access)
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Chemical proteomics versus LeishmaniasisIn: Chemistry and Biology Jg. 22 (2015) Nr. 3, S. 309 - 310ISSN: 1879-1301; 1074-5521Online Volltext: dx.doi.org/ (Open Access)
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Determinants of amyloid fibril degradation by the PDZ protease HTRA1In: Nature Chemical Biology Jg. 11 (2015) Nr. 11, S. 862 - 869ISSN: 1552-4450; 1552-4469Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Reply to Liu et al. : Loss of TGF-β signaling in CARASIL pathogenesisIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 14, S. E1694ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/
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Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signalingIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 111 (2014) Nr. 46, S. 16496 - 16501ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/
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Substrate occupancy at the onset of oligomeric transitions of DegPIn: Structure Jg. 22 (2014) Nr. 2, S. 281 - 290ISSN: 1878-4186Online Volltext: dx.doi.org/
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Ahp cyclodepsipeptides: The impact of the ahp residue on the "Canonical Inhibition" of S1 serine proteasesIn: ChemBioChem Jg. 14 (2013) Nr. 11, S. 1301 - 1308ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/
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Diversity of allosteric regulation in proteasesIn: ACS Chemical Biology Jg. 8 (2013) Nr. 1, S. 19 - 26ISSN: 1554-8937; 1554-8929Online Volltext: dx.doi.org/
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Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatisIn: Molecular Microbiology Jg. 89 (2013) Nr. 4, S. 676 - 689ISSN: 1365-2958; 1365-2958Online Volltext: dx.doi.org/
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XCtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in bacillus subtilisIn: Cell (Cambridge, Mass) Jg. 155 (2013) Nr. 3, S. 647 - 658ISSN: 1097-4172; 1097-4172Online Volltext: dx.doi.org/
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Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ ProteaseIn: ChemBioChem Jg. 13 (2012) Nr. 3, S. 402 - 408ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/
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Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degenerationIn: The Journal of Biological Chemistry (JBC) Jg. 287 (2012) Nr. 25, S. 21335 - 21345ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/
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Development of a Solid-Phase Approach to the Natural Product Class of Ahp-Containing CyclodepsipeptidesIn: European Journal of Organic Chemistry (2012) Nr. 8, S. 1616 - 1625ISSN: 1099-0690; 0075-4617; 0170-2041; 0365-5490; 0947-3440; 1434-193X; 1434-243XOnline Volltext: dx.doi.org/
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E. coli LoiP (YggG), a metalloprotease hydrolyzing Phe–Phe bondsIn: Molecular BioSystems Jg. 8 (2012) Nr. 6, S. 1775 - 1782ISSN: 1742-206X; 1742-2051Online Volltext: dx.doi.org/ Online Volltext
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Genetic analysis of 15 protein folding factors and proteases of the Escherichia coli cell envelopeIn: Journal of Bacteriology Jg. 194 (2012) Nr. 12, S. 3225 - 3233ISSN: 0021-9193; 1098-5530Online Volltext: dx.doi.org/
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Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregatesIn: The Journal of Biological Chemistry (JBC) Jg. 287 (2012) Nr. 25, S. 20931 - 20941ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/
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Human serine protease HTRA1 positively regulates osteogenesis of human bone marrow-derived mesenchymal stem cells and mineralization of differentiating bone-forming cells through the modulation of extracellular matrix proteinIn: Stem Cells Jg. 30 (2012) Nr. 10, S. 2271 - 2282ISSN: 1549-4918; 1066-5099Online Volltext: dx.doi.org/ (Open Access)
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MiR-30e and miR-181d control Radial Glia cell proliferation via HtrA1 modulationIn: Cell Death and Disease Jg. 3 (2012) Nr. 8, S. e360ISSN: 2041-4889Online Volltext: dx.doi.org/ (Open Access)
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Newly folded substrates inside the molecular cage of the HtrA chaperone DegQIn: Nature Structural & Molecular Biology Jg. 19 (2012) Nr. 2, S. 152 - 157ISSN: 1545-9993Online Volltext: dx.doi.org/
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HTRA proteases : regulated proteolysis in protein quality controlIn: Nature Reviews Molecular Cell Biology Jg. 12 (2011) Nr. 3, S. 152 - 162ISSN: 1471-0072Online Volltext: dx.doi.org/
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Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteinsIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 42, S. 16958 - 16969ISSN: 0002-7863; 1520-5126Online Volltext: dx.doi.org/
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Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelopeIn: The Journal of Biological Chemistry (JBC) Jg. 286 (2011) Nr. 35, S. 30680 - 30690ISSN: 0021-9258; 1083-351XOnline Volltext: dx.doi.org/
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Peptide Functionalized Polydiacetylene Liposomes Act as a Fluorescent Turn-On Sensor for Bacterial LipopolysaccharideIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 25, S. 9720 - 9723ISSN: 0002-7863; 1520-5126Online Volltext: dx.doi.org/
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Protein quality control in the bacterial periplasmIn: Annual Review of Microbiology Jg. 65 (2011) S. 149 - 168ISSN: 1545-3251; 0066-4227Online Volltext: dx.doi.org/
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Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposureIn: Nature Structural & Molecular Biology Jg. 18 (2011) Nr. 6, S. 728 - 731ISSN: 1545-9993Online Volltext: dx.doi.org/
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Substrate induced remodeling of the active site regulates human HtrA1 activityIn: Nature Structural & Molecular Biology Jg. 18 (2011) S. 386 - 388ISSN: 1545-9993Online Volltext: dx.doi.org/
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Conversion of a regulatory into a degradative proteaseIn: Journal of Molecular Biology (JMB) Jg. 397 (2010) Nr. 4, S. 957 - 966ISSN: 1089-8638; 0022-2836Online Volltext: dx.doi.org/
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Determinants of structural and functional plasticity of a widely conserved protease chaperone complexIn: Nature Structural & Molecular Biology Jg. 17 (2010) Nr. 7, S. 837 - 843ISSN: 1545-9993; 1545-9985Online Volltext: dx.doi.org/
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Molecular transformers in the cell: lessons learned from the DegP protease-chaperoneIn: Current Opinion in Structural Biology Jg. 20 (2010) Nr. 2, S. 253 - 258ISSN: 0959-440X; 1879-033XOnline Volltext: dx.doi.org/
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Solid phase total synthesis of the 3-amino-6-hydroxy-2-piperidone (Ahp) cyclodepsipeptide and protease inhibitor Symplocamide A.In: Chemical Communications: ChemComm (2010) Nr. 46, S. 8857 - 8859ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345Online Volltext: dx.doi.org/
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The serine protease HtrA1 specifically interacts and degrades the tuberous sclerosis complex 2 proteinIn: Molecular Cancer Research Jg. 8 (2010) Nr. 9, S. 1248 - 1260ISSN: 1557-3125; 1541-7786Online Volltext: dx.doi.org/
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Peptidic small molecule activators of the stress sensor DegSIn: Molecular BioSystems Jg. 5 (2009) Nr. 9, S. 980 - 985ISSN: 1742-206X; 1742-2051Online Volltext: dx.doi.org/
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Selectivity profiling of DegP substrates and inhibitorsIn: Bioorganic and Medicinal Chemistry Jg. 17 (2009) Nr. 7, S. 2920 - 2924ISSN: 0968-0896; 1464-3391Online Volltext: dx.doi.org/
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Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coliIn: Research in Microbiology Jg. 160 (2009) Nr. 9, S. 660 - 666ISSN: 0923-2508; 1769-7123Online Volltext: dx.doi.org/
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Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality controlIn: Angewandte Chemie International Edition Jg. 47 (2008) Nr. 7, S. 1332 - 1334ISSN: 1521-3773; 1433-7851; 0570-0833Online Volltext: dx.doi.org/
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Allosteric regulation of proteasesIn: ChemBioChem Jg. 9 (2008) Nr. 18, S. 2920 - 2928ISSN: 1439-4227; 1439-7633Online Volltext: dx.doi.org/ Online Volltext
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HtrA1-dependent proteolysis of TGF-β controls both neuronal maturation and developmental survivalIn: Cell Death and Differentiation Jg. 15 (2008) Nr. 9, S. 1408 - 1416ISSN: 1350-9047; 1476-5403Online Volltext: dx.doi.org/ Online Volltext
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Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteinsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 22 (2008) S. 7702 - 7707ISSN: 1091-6490; 0027-8424
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Structural basis for the regulated protease and chaperone function of DegP.In: Nature (2008) Nr. 453, S. 885 - 890ISSN: 0028-0836; 1476-4687
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The serine protease HtrA1 is a novel prognostic factor for human mesotheliomaIn: Pharmacogenomics Jg. 9 (2008) Nr. 8, S. 1069 - 1077ISSN: 1462-2416
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Determinants of regulated proteolysis in signal transductionIn: Genes and Development Jg. 21 (2007) Nr. 1, S. 6 - 10ISSN: 0890-9369Online Volltext: dx.doi.org/
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Identification of Protein Disulfide Isomerase as a Cardiomyocyte Survival Factor in Ischemic CardiomyopathyIn: Journal of the American College of Cardiology Jg. 50 (2007) Nr. 11, S. 1029 - 1037ISSN: 0735-1097Online Volltext: dx.doi.org/ (Open Access)
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Regulation of the σE stress response by DegS: How the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stressIn: Genes and Development Jg. 21 (2007) Nr. 20, S. 2659 - 2670ISSN: 0890-9369; 1549-5477Online Volltext: dx.doi.org/
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Target directed proteolysis in vivo.In: Methods in Enzymology Jg. 421 (2007) S. 68 - 83ISSN: 0076-6879; 1557-7988
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Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritisIn: Arthritis & Rheumatism Jg. 54 (2006) Nr. 5, S. 1662 - 1672ISSN: 1529-0131; 0004-3591Online Volltext: dx.doi.org/
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Serine protease HtrA1 modulates chemotherapy-induced cytotoxicityIn: The Journal of Clinical Investigation (JCI) Jg. 116 (2006) Nr. 7, S. 1994 - 2004ISSN: 1558-8238; 0021-9738Online Volltext: dx.doi.org/
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The role of human HtrA1 in arthritic disease.In: The Journal of Biological Chemistry (JBC) Jg. 281 (2006) Nr. 10, S. 6124 - 6129ISSN: 0021-9258; 1083-351X
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Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometryIn: European Journal of Mass Spectrometry Jg. 11 (2005) Nr. 5, S. 547 - 555ISSN: 1469-0667
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Implications of human HtrA1 in amyloid precursor protein processing.In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 102 (2005) Nr. 17, S. 6021 - 6026ISSN: 1091-6490; 0027-8424
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Implications of the serine protease HtrA1 in amyloid precursor protein processingIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 102 (2005) Nr. 17, S. 6021 - 6026ISSN: 1091-6490; 0027-8424
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Target-directed proteolysis at the ribosome.In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 102 (2005) S. 4246 - 4251ISSN: 1091-6490; 0027-8424
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Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteinsIn: Molecular Membrane Biology Jg. 21 (2004) Nr. 6, S. 373 - 383ISSN: 0968-7688Online Volltext: dx.doi.org/
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Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a proteaseIn: Cell Jg. 117 (2004) Nr. 4, S. 483 - 494ISSN: 0092-8674
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Proteolysis as a regulatory mechanismIn: Annual Review of Genetics Jg. 38 (2004) S. 709 - 724ISSN: 0066-4170; 0066-4197
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Context-dependent effects of charged residues in transmembrane segments of MalF-PhoA fusionsIn: Research in Microbiology Jg. 154 (2003) Nr. 9, S. 654 - 657ISSN: 0923-2508; 1769-7123
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SecA-dependent quality control of intracellular protein localizationIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 100 (2003) Nr. 23, S. 13231 - 13234ISSN: 1091-6490; 0027-8424
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Crystal structure of DegP (HtrA) reveals a new protease-chaperone machineIn: Nature Jg. 416 (2002) Nr. 6879, S. 455 - 459ISSN: 0028-0836; 1476-4687
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The HtrA family of proteases : Implications for protein composition and cell fateIn: Molecular Cell Jg. 10 (2002) Nr. 3, S. 443 - 455ISSN: 1097-2765; 1097-4164Online Volltext: dx.doi.org/
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A Novel Method to Determine the Topology of Peroxisomal Membrane Proteins in Vivo Using the Tobacco Etch Virus ProteaseIn: The Journal of Biological Chemistry (JBC) Jg. 276 (2001) Nr. 39, S. 36501 - 36507ISSN: 0021-9258; 1083-351X
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Characterization of transmembrane segments 3, 4, and 5 of Ma1F by mutational analysisIn: Journal of Bacteriology Jg. 183 (2001) Nr. 1, S. 375 - 381ISSN: 0021-9193
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Evidence for coupling of membrane targeting and function of the signal recognition particle (SRP) receptor Fts YIn: EMBO Reports Jg. 2 (2001) Nr. 11, S. 1040 - 1046ISSN: 1469-3178; 1469-221X
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Determinants of translocation and folding of TreF, a trehalase of Escherichia coliIn: The Journal of Biological Chemistry (JBC) Jg. 275 (2000) Nr. 31, S. 23439 - 23445ISSN: 0021-9258; 1083-351X
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Synthesis of acyclic 6,7-dihaloquinolone nucleoside analogues as potential antibacterial and antiviral agents.In: Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines Jg. 8 (2000) Nr. 6, S. 1407 - 1413ISSN: 0968-0896
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A temperature-dependent switch from chaperone to protease in a widely conserved heat shock proteinIn: Cell Jg. 97 (1999) Nr. 3, S. 339 - 347ISSN: 0092-8674
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Membrane topology of CadA homologous P-type ATPase of Helicobacter pylori as determined by expression of phoA fusions in Escherichia coli and the positive inside ruleIn: Research in Microbiology Jg. 150 (1999) Nr. 8, S. 507 - 520ISSN: 0923-2508; 1769-7123
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Membrane topology of the xenobiotic-exporting subunit, MexB, of the MexA,B-OprM extrusion pump in Pseudomonas aeruginosaIn: The Journal of Biological Chemistry (JBC) Jg. 274 (1999) Nr. 15, S. 10517 - 10522ISSN: 0021-9258; 1083-351X
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Eine hochspezifische Protease zur Struktur-und Funktionsanalyse von Proteinen in vivo und in vitro.In: Biospektrum: das Magazin für Biowissenschaften Jg. 3 (1998) S. 53 - 56ISSN: 0947-0867
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Polypeptide binding of Escherichia coil FtsH (HflB)In: Molecular Microbiology Jg. 28 (1998) Nr. 4, S. 803 - 812ISSN: 0950-382X
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Quinolone nucleosides: 6,7-dihalo-N-β- and α-glycosyl-1,4-dihydro-4- oxo-quinoline-3-carboxylic acids and derivatives. Synthesis, antimicrobial and antiviral activityIn: Nucleosides and Nucleotides Jg. 17 (1998) Nr. 12, S. 2255 - 2266ISSN: 1525-7770
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The ABC maltose transporterIn: Molecular Microbiology Jg. 29 (1998) Nr. 3, S. 685 - 694ISSN: 0950-382X
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The protein translocation apparatus contributes to determining the topology of an integral membrane protein in Escherichia coliIn: The Journal of Biological Chemistry (JBC) Jg. 273 (1998) Nr. 14, S. 8419 - 8424ISSN: 0021-9258; 1083-351X
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Biochemical characterization and mass spectrometric disulfide bond mapping of periplasmic α-amylase mals of Escherichia coliIn: The Journal of Biological Chemistry (JBC) Jg. 272 (1997) Nr. 35, S. 22125 - 22133ISSN: 0021-9258; 1083-351X
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Biogenese, Struktur und Funktion integraler Membranproteine: die Membrankomponenten des ABC-Maltosetransporters von Escherichia coli.In: Biospektrum: das Magazin für Biowissenschaften Jg. 2 (1997) S. 46 - 47ISSN: 0947-0867
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TnTIN and TnTAP: Mini-transposons for site-specific proteolysis in vivoIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 94 (1997) Nr. 24, S. 13111 - 13115ISSN: 1091-6490; 0027-8424
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Characterization of a cytoplasmic trehalase of Escherichia coliIn: Journal of bacteriology : JB Jg. 178 (1996) Nr. 21, S. 6250 - 6257ISSN: 0021-9193
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Characterization of transmembrane domains 6, 7, and 8 of MalF by mutational analysisIn: Journal of bacteriology : JB Jg. 178 (1996) Nr. 8, S. 2255 - 2262ISSN: 0021-9193
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Site-specific proteolysis of the Escherichia coli SecA protein in vivoIn: Journal of bacteriology : JB Jg. 178 (1996) Nr. 10, S. 2986 - 2988ISSN: 0021-9193
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Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocaseIn: The EMBO Journal Jg. 15 (1996) Nr. 19, S. 5209 - 5217ISSN: 0261-4189; 1460-2075
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Synthetic competition between cytoplasmic folding and translocation of a soluble membrane protein domainIn: Research in Microbiology Jg. 146 (1995) Nr. 2, S. 121 - 128ISSN: 0923-2508; 1769-7123
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Requirements for translocation of periplasmic domains in polytopic membrane proteinsIn: Journal of bacteriology : JB Jg. 176 (1994) Nr. 15, S. 4565 - 4571ISSN: 0021-9193
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Sec-independent translocation of a 100-residue periplasmic N-terminal tail in the E.coli inner membrane protein proWIn: The EMBO Journal Jg. 13 (1994) Nr. 19, S. 4653 - 4661ISSN: 0261-4189; 1460-2075
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The Saccharomyces cerevisiae gene PPH3 encodes a protein phosphatase with properties different from PPX, PP1 and PP2AIn: Yeast : a forum for yeast researchers Jg. 10 (1994) Nr. 5, S. 567 - 578ISSN: 0749-503X
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Decoding signals for membrane protein assembly using alkaline phosphatase fusionsIn: The EMBO Journal Jg. 10 (1991) Nr. 10, S. 2773 - 2782ISSN: 0261-4189; 1460-2075
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Proper insertion of a complex membrane protein in the absence of its amino-terminal export signalIn: The Journal of Biological Chemistry (JBC) Jg. 266 (1991) Nr. 25, S. 16530 - 16533ISSN: 0021-9258; 1083-351X
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Genetic analysis of membrane protein topology by a sandwich gene fusion approach.In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 87 (1990) Nr. 19, S. 7574 - 7578ISSN: 1091-6490; 0027-8424
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MalI, a novel protein involved in regulation of the maltose system of Escherichia coli, is highly homologous to the repressor proteins GalR, CytR, and LacI.In: Journal of bacteriology : JB Jg. 171 (1989) Nr. 9, S. 4888 - 4899ISSN: 0021-9193
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The Janus-faced role of KDM5B heterogeneity in melanoma : Differentiation as a situational driver of both growth arrest and drug-resistance(2020) 50 SeitenOnline Volltext: dx.doi.org/ (Open Access)