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Prof. Dr. rer. nat. Mengji Lu

Institut für Virologie der Medizinischen Fakultät
Anschrift
Virchowstr. 179 / Robert-Koch-Haus
45147 Essen
Telefon
+49 201 723 3530
E-Mail
mengji.lu@uni-due.de
Webseite
http://www.uni-due.de/virologie/res_lu_en.html

Funktionen

  • Universitätsprofessor/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Liu, Jia; Yang, Xuecheng; Wang, Hua; Li, Ziwei; Deng, Hui; Liu, Jing; Xiong, Shue; He, Junyi; Feng, Xuemei; Guo, Chunxia; Wang, Weixian; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Senff, Tina; Menne, Christopher; Timm, Jörg; Zhang, Yanfang; Deng, Fei; Lu, Yinping; Wu, Jun; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Wang, Baoju; Zheng, Xin
    Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairment
    In: mBio Jg. 12 (2021) Nr. 2, S. e00085 - 21
    ISSN: 2150-7511; 2161-2129
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Zhou, Xueshi; Lu, Hongzhou; Lu, Mengji; Huang, Lihua
    Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver Disease
    In: Frontiers in Medicine Jg. 8 (2021)
    ISSN: 2296-858X
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Yanqin; Yang, Xiaoli; Li, Jia; Sokolova, Viktoriya; Zou, Shi; Han, Meihong; Yan, Hu; Wey, Karolin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Epple, Matthias; Wu, Jun
    Delivery of toll-like receptor 3 ligand poly(I:C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect in a mouse model
    In: Acta Biomaterialia (2021)
    ISSN: 1878-7568; 1742-7061
    Online Volltext: dx.doi.org/
  • Chen, Jieliang; Li, Yaming; Lai, Fritz; Wang, Yang; Sutter, Kathrin; Dittmer, Ulf; Ye, Jianyu; Zai, Wenjing; Liu, Min; Shen, Fang; Wu, Min; Hu, Kongying; Li, Baocun; Lu, Mengji; Zhang, Xiaonan; Zhang, Jiming; Li, Jianhua; Chen, Qingfeng; Yuan, Zhenghong
    Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ Signaling
    In: Hepatology Jg. 73 (2021) Nr. 2, S. 486 - 502
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/
  • Li, Qian; Wang, Jun; Islam, Heba; Kirschning, Carsten Jürgen; Lu, Hongzhou; Hoffmann, Daniel; Dittmer, Ulf; Lu, Mengji
    Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis
    In: Cell Death and Disease Jg. 12 (2021) Nr. 1, S. 34
    ISSN: 2041-4889
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhou, Li; He, Rui; Fang, Peining; Li, Mengqi; Yu, Haisheng; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Lin, Yong; Zhang, Rui; Trilling, Mirko; Bröring, Ruth; Lu, Mengji; Zhu, Ying; Liu, Shi
    Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 98
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Luo, Xufeng; Zhang, Rui; Lu, Mengji; Liu, Shi; Baba, Hideo Andrea; Gerken, Guido; Wedemeyer, Heiner; Bröring, Ruth
    Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 12 (2021)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Yanqin; Yan, Hu; Zou, Shi; Khera, Tanvi; Li, Jia; Han, Meihong; Yang, Xiaoli; Wang, Baoju; Liu, Jia; Sun, Shuilin; Zheng, Xin; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang; Wedemeyer, Heiner; Wu, Jun
    Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model
    In: Hepatology Communications (2021) in press
    ISSN: 2471-254X
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, Hongming; Rückborn, Meike; Le-Trilling, Vu Thuy Khanh; Zhu, Dan; Yang, Shangqing; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Yinping; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Trilling, Mirko; Liu, Jia
    Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in mice
    In: European Journal of Immunology Jg. 51 (2021) Nr. 2, S. 393 - 407
    ISSN: 1521-4141; 0014-2980
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, Xuan; Zhang, Xiaoyong; Lu, Mengji
    Recent trends in the development of Toll-like receptor 7/8-targeting therapeutics
    In: Expert Opinion on Drug Discovery (2021) in press
    ISSN: 1746-045X; 1746-0441
    Online Volltext: dx.doi.org/
  • Wu, Jun; Liang, Boyun; Chen, Cunrong; Wang, Hua; Fang, Yaohui; Shen, Shu; Yang, Xiaoli; Wang, Baoju; Chen, Liangkai; Chen, Qi; Wu, Yang; Liu, Jia; Yang, Xuecheng; Li, Wei; Zhu, Bin; Zhou, Wenqing; Wang, Huan; Li, Sumeng; Lu, Sihong; Liu, Di; Li, Huadong; Krawczyk, Adalbert; Lu, Mengji; Yang, Dongliang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 1813
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Yanqin; Anastasiou, Olympia E.; Strunz, Benedikt; Scheuten, Janina; Bremer, Birgit; Kraft, Anke; Kleinsimglinhaus, Karolina; Todt, Daniel; Bröring, Ruth; Hardtke-Wolenski, Matthias; Wu, Jun; Yang, Dongliang; Dittmer, Ulf; Lu, Mengji; Cornberg, Markus; Björkström, Niklas K.; Khera, Tanvi; Wedemeyer, Heiner
    The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B virus infection
    In: Liver International (2021) in press
    ISSN: 1478-3231; 1478-3223; 1600-0676; 0106-9543
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhao, Zhenyu; Lu, Kefeng; Mao, Binli; Liu, Shi; Trilling, Mirko; Huang, Ailong; Lu, Mengji; Lin, Yong
    The interplay between emerging human coronavirus infections and autophagy
    In: Emerging Microbes and Infections Jg. 10 (2021) Nr. 1, S. 196 - 205
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Shichuan; Trilling, Mirko; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Zheng, Xin; Yang, Dongliang; Liu, Jia
    A Crowned Killer’s Résumé : Genome, Structure, Receptors, and Origin of SARS-CoV-2
    In: Virologica Sinica (2020)
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Wang, Xueyu; Lin, Yong; Kemper, Thekla; Chen, Jieliang; Yuan, Zhenghong; Liu, Shi; Zhu, Ying; Bröring, Ruth; Lu, Mengji
    AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy
    In: Cellular Microbiology Jg. 22 (2020) Nr. 2, S. e13131
    ISSN: 1462-5814; 1462-5822
    Online Volltext: dx.doi.org/ (Open Access)
  • Weng, Zhihong; Chen, Qiaosen; Li, Sumeng; Li, Huadong; Zhang, Qian; Lu, Sihong; Wu, Li; Xiong, Leiqun; Mi, Bobin; Liu, Di; Lu, Mengji; Yang, Dongliang; Jiang, Hongbo; Zheng, Shaoping; Zheng, Xin
    ANDC : An early warning score to predict mortality risk for patients with Coronavirus Disease 2019
    In: Journal of Translational Medicine Jg. 18 (2020) Nr. 1, S. 328
    ISSN: 1479-5876
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Lu, Mengji; Qiu, Yuanwang; Lu, Hongzhou
    Acute-on-Chronic Liver Failure From Chronic-Hepatitis-B, Who Is the Behind Scenes
    In: Frontiers in Microbiology Jg. 11 (2020) S. 583423
    ISSN: 1664-302X
    Online Volltext: dx.doi.org/ (Open Access)
  • Meng, Zhongji; Chen, Yuanyuan; Lu, Mengji
    Advances in Targeting the Innate and Adaptive Immune Systems to Cure Chronic Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 10 (2020) S. 3217
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Han, Mingfeng; Xu, Mengyuan; Zhang, Yafei; Liu, Zhongping; Li, Shasha; He, Tengfei; Li, Jinsong; Gao, Yong; Liu, Wanjun; Li, Tuantuan; Chen, Zixiang; Huang, Xin; Cheng, Guoling; Wang, Jun; Dittmer, Ulf; Witzke, Oliver; Zou, Guizhou; Li, Xiuyong; Lu, Mengji; Zhang, Zhenhua
    Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity
    In: Medical Microbiology and Immunology Jg. 209 (2020) S. 657 - 668
    ISSN: 1432-1831; 0300-8584
    Online Volltext: dx.doi.org/
  • Xu, Ling; Liu, Jia; Lu, Mengji; Yang, Dongliang; Zheng, Xin
    Author response to Letter to the Editor : Potential implications of COVID-19 in non-alcoholic fatty liver disease
    In: Liver International Jg. 40 (2020) Nr. 10, S. 2569 - 2570
    ISSN: 1478-3231; 1600-0676; 0106-9543; 1478-3223
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Luo, Xufeng; Liu, Jia; Lu, Mengji
    Controversial: Early Innate Responses to Hepatitis B Virus Infection, an Explanation for Viral Persistence?
    In: Virologica Sinica (2020)
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Yafei; Wang, Changtai; Han, Mingfeng; Ye, Jun; Gao, Yong; Liu, Zhongping; He, Tengfei; Li, Tuantuan; Xu, Mengyuan; Zhou, Luping; Zou, Guizhou; Lu, Mengji; Zhang, Zhenhua
    Correction to: Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference
    In: Virologica Sinica Jg. 35 (2020) Nr. 6, S. 885 - 886
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Xu, Chunli; Lu, Yinping; Zheng, Xin; Feng, Xuemei; Yang, Xuecheng; Timm, Jörg; Wu, Jun; Wang, Baoju; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Corrigendum: TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure (Frontiers in Immunology, (2017), 8, 10.3389/fimmu.2017.01609)
    In: Frontiers in Immunology Jg. 11 (2020) S. 1566
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Mengmeng; Xiong, Yan; Li, Mingyue; Zhang, Wenjing; Liu, Jia; Zhang, Yanfang; Xiong, Shue; Zou, Congcong; Liang, Boyun; Lu, Mengji; Yang, Dongliang; Peng, Cheng; Zheng, Xin
    Depletion but Activation of CD56dⁱmCD16⁺ NK Cells in Acute Infection with Severe Fever with Thrombocytopenia Syndrome Virus
    In: Virologica Sinica (2020)
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Liu, Anding; Wang, Wenjie; Zhao, Xuecheng; Zhou, Xiaoxi; Yang, Dongliang; Lu, Mengji; Lv, Yongman
    Disappearance of antibodies to SARS-CoV-2 in a -COVID-19 patient after recovery
    In: Clinical Microbiology and Infection Jg. 26 (2020) Nr. 12, S. 1703 - 1705
    ISSN: 1469-0691; 1198-743X
    Online Volltext: dx.doi.org/
  • Zhang, Yafei; Wang, Changtai; Han, Mingfeng; Ye, Jun; Gao, Yong; Liu, Zhongping; He, Tengfei; Li, Tuantuan; Xu, Mengyuan; Zhou, Luping; Zou, Guizhou; Lu, Mengji; Zhang, Zhenhua
    Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference
    In: Virologica Sinica Jg. 35 (2020) Nr. 6, S. 758 - 767
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Erratum for Westmeier et al., "Impaired Cytotoxic CD8⁺ T Cell Response in Elderly COVID-19 Patients"
    In: mBio Jg. 11 (2020) Nr. 5, S. 02243 - 02220
    ISSN: 2150-7511
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Jun; Li, Qian; Yin, Yongmei; Zhang, Yingying; Cao, Yingying; Lin, Xiaoming; Huang, Lihua; Hoffmann, Daniel; Lu, Mengji; Qiu, Yuanwang
    Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19
    In: Frontiers in Immunology Jg. 11 (2020)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rojas-Sánchez, Leonardo; Zhang, Ejuan; Sokolova, Viktoriya; Zhong, Maohua; Yan, Hu; Lu, Mengji; Li, Qian; Yan, Huimin; Epple, Matthias
    Genetic immunization against hepatitis B virus with calcium phosphate nanoparticles in vitro and in vivo
    In: Acta Biomaterialia: Structure, property, function ; relationships in biomaterials Jg. 110 (2020) S. 254 - 265
    ISSN: 1878-7568; 1742-7061
    Online Volltext: dx.doi.org/
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Liu, Shi; Zhao, Kaitao; Kemper, Thekla; Yu, Haisheng; Li, Mengqi; Zhang, Jiming; Chen, Mingzhou; Zhu, Ying; Chen, Xinwen; Lu, Mengji
    Glucosamine promotes hepatitis B virus replication through its dual effects in suppressing autophagic degradation and inhibiting MTORC1 signaling
    In: Autophagy Jg. 16 (2020) Nr. 3, S. 548 - 561
    ISSN: 1554-8635; 1554-8627
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Zhenhua; Trippler, Martin; Real, Catherine I.; Werner, Melanie; Luo, Xufeng; Schefczyk, Stefan; Kemper, Thekla; Anastasiou, Olympia E.; Ladiges, Yvonne; Treckmann, Jürgen Walter; Paul, Andreas; Baba, Hideo Andreas; Allweiss, Lena; Dandri, Maura; Gerken, Guido; Wedemeyer, Heiner; Schlaak, Jörg Friedrich; Lu, Mengji; Bröring, Ruth
    Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes
    In: Hepatology: official journal of the American Association for the Study of Liver Diseases Jg. 72 (2020) Nr. 3, S. 829 - 844
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/ (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Impaired cytotoxic CD8⁺ T cell response in elderly COVID-19 patients
    In: mBio Jg. 11 (2020) Nr. 5, S. e02243 - 20
    ISSN: 2150-7511; 2161-2129
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Yong; Zhao, Zhenyu; Huang, Ailong; Lu, Mengji
    Interplay between Cellular Autophagy and Hepatitis B Virus Replication : A Systematic Review
    In: Cells Jg. 9 (2020) Nr. 9, S. 2101
    ISSN: 2073-4409
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xu, Ling; Liu, Jia; Lu, Mengji; Yang, Dongliang; Zheng, Xin
    Liver injury during highly pathogenic human coronavirus infections
    In: Liver International: official journal of the International Association for the Study of the Liver Jg. 40 (2020) Nr. 5, S. 998 - 1004
    ISSN: 1478-3231; 1478-3223
    Online Volltext: dx.doi.org/
  • Liu, Jing; Li, Sumeng; Liu, Jia; Liang, Boyun; Wang, Xiaobei; Wang, Hua; Li, Wei; Tong, Qiaoxia; Yi, Jianhua; Zhao, Lei; Xiong, Lijuan; Guo, Chunxia; Tian, Jin; Luo, Jinzhuo; Yao, Jinghong; Pang, Ran; Shen, Hui; Peng, Cheng; Liu, Ting; Zhang, Qian; Wu, Jun; Xu, Ling; Lu, Sihong; Wang, Baoju; Weng, Zhihong; Han, Chunrong; Zhu, Huabing; Zhou, Ruxia; Zhou, Helong; Chen, Xiliu; Ye, Pian; Zhu, Bin; Wang, Lu; Zhou, Wenqing; He, Shengsong; He, Yongwen; Jie, Shenghua; Wei, Ping; Zhang, Jianao; Lu, Yinping; Wang, Weixian; Zhang, Li; Li, Ling; Zhou, Fengqin; Wang, Jun; Dittmer, Ulf; Lu, Mengji; Hu, Yu; Yang, Dongliang; Zheng, Xin
    Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients
    In: EBioMedicine Jg. 55 (2020)
    ISSN: 2352-3964
    Online Volltext: dx.doi.org/ (Open Access)
  • Yu, Haisheng; Li, Menqui; He, Rui; Fang, Peining; Wang, Qiming; Yi, Yu; Wang, Fubing; Zhou, Li; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Liu, Dan; Trilling, Mirko; Bröring, Ruth; Wiemer, Erik A.C.; Lu, Mengji; Zhu, Ying; Liu, Shi
    Major Vault Protein Promotes Hepatocellular Carcinoma Through Targeting Interferon Regulatory Factor 2 and Decreasing p53 Activity
    In: Hepatology Jg. 72 (2020) Nr. 2, S. 518 - 534
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/
  • Wang, Xueyu; Lin, Yong; Liu, Shi; Zhu, Ying; Lu, Kefeng; Bröring, Ruth; Lu, Mengji
    O-GlcNAcylation modulates HBV replication through regulating cellular autophagy at multiple levels
    In: FASEB Journal Jg. 34 (2020) Nr. 11, S. 14473 - 14489
    ISSN: 1530-6860; 0892-6638
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Jia; Zheng, Xin; Tong, Qiaoxia; Li, Wei; Wang, Baoju; Sutter, Kathrin; Trilling, Mirko; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang
    Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV
    In: Journal of Medical Virology Jg. 92 (2020) Nr. 5, S. 491 - 494
    ISSN: 1096-9071; 0146-6615
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lin, Yong; Yuan, Jun; Long, Quanxin; Hu, Jieli; Deng, Haijun; Zhao, Zhenyu; Chen, Juan; Lu, Mengji; Huang, Ailong
    Patients with SARS-CoV-2 and HBV co-infection are at risk of greater liver injury
    In: Genes & Diseases (2020) in press
    ISSN: 2352-3042
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Hongjun; Zhou, Jiao; Xiao, Peng; Lin, Yong; Gong, Xin; Liu, Shiyan; Xu, Qingjia; Wang, Minjin; Ren, Haiyan; Lu, Mengji; Wang, Yuan; Zhu, Jing; Xie, Zhiping; Li, Huihui; Lu, Kefeng
    PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes
    In: Autophagy (2020) in press
    ISSN: 1554-8635; 1554-8627
    Online Volltext: dx.doi.org/
  • Yan, Hu; Zhong, Maohua; Yang, Jingyi; Guo, Jiabao; Yu, Jie; Yang, Yi; Ma, Zhiyong; Zhao, Bali; Zhang, Yue; Wang, Junzhong; Wu, Chunchen; Dittmer, Ulf; Yang, Dongliang; Lu, Mengji; Zhang, Ejuan; Yan, Huimin
    TLR5 activation in hepatocytes alleviates the functional suppression of intrahepatic CD8⁺ T cells
    In: Immunology Jg. 161 (2020) Nr. 4, S. 325 - 344
    ISSN: 1365-2567; 0019-2805
    Online Volltext: dx.doi.org/
  • Zhang, Ejuan; Yan, Hu; Li, Qian; Dittmer, Ulf; Yan, Huimin; Lu, Mengji
    Activation of the TLR signaling pathway in CD8+ T cells counteracts liver endothelial cell-induced T cell tolerance
    In: Cellular & Molecular Immunology Jg. 16 (2019) Nr. 9, S. 774 - 776
    ISSN: 2042-0226; 1672-7681
    Online Volltext: dx.doi.org/
  • Yan, Yan; Chen, Renfang; Wang, Xu; Hu, Kai; Huang, Lihua; Lu, Mengji; Hu, Qinxue
    CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions in Viral Infection and Prevention
    In: Frontiers in Cell and Developmental Biology Jg. 7 (2019) S. 212
    ISSN: 2296-634X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wu, Chunchen; Li, Baolin; Zhang, Xiaoyong; Zhao, Kaitao; Chen, Yingshan; Yuan, Yifei; Liu, Yan; Chen, Rongjuan; Xu, Dongping; Chen, Xinwen; Lu, Mengji
    Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs
    In: Virologica Sinica Jg. 34 (2019) Nr. 4, S. 377 - 385
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, Shi; Liu, Li; Xu, Gang; Cao, Zhongying; Wang, Qing; Li, Shun; Peng, Nanfang; Yin, Jingchuan; Yu, Haisheng; Li, Mengqi; Xia, Zhangchuan; Zhou, Li; Lin, Yong; Wang, Xueyu; Li, Qian; Zhu, Chengliang; Yang, Xuecheng; Wang, Jun; She, Yinglong; Lu, Mengji; Zhu, Ying
    Epigenetic Modification Is Regulated by the Interaction of Influenza A Virus Nonstructural Protein 1 with the De Novo DNA Methyltransferase DNMT3B and Subsequent Transport to the Cytoplasm for K48-Linked Polyubiquitination
    In: Journal of Virology Jg. 93 (2019) Nr. 7,
    ISSN: 1098-5514
    Online Volltext: dx.doi.org/
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Kemper, Thekla; Squire, Anthony; Gunzer, Matthias; Zhang, Jiming; Chen, Xinwen; Lu, Mengji
    Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components
    In: Protein & Cell Jg. 10 (2019) Nr. 1, S. 60 - 66
    ISSN: 1674-8018; 1674-800X
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Yan; Zhou, Yi; Li, Xiaodong; Niu, Ming; Chen, Rongjuan; Shao, Jinman; Si, Lanlan; Luo, Dan; Lin, Yayun; Li, Le; Zhang, Kai; Xiao, Xiaohe; Xu, Zhihui; Liu, Min; Lu, Mengji; Zoulim, Fabien; Xu, Dongping
    Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice
    In: Emerging Microbes & Infections Jg. 8 (2019) Nr. 1, S. 354 - 365
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Jinyu; Li, Jing; Wu, Jingwen; Dong, Minhui; Shen, Zhongliang; Lin, Yong; Li, Fahong; Zhang, Yongmei; Mao, Richeng; Lu, Mengji; Zhang, Jiming
    Host Gene SEL1L Involved in Endoplasmic Reticulum-Associated Degradation Pathway Could Inhibit Hepatitis B Virus at RNA, DNA, and Protein Levels
    In: Frontiers in Microbiology Jg. 10 (2019)
    ISSN: 1664-302X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhang, Zhenhua; Wang, Changtai; Liu, Zhongping; Zou, Guizhou; Li, Jun; Lu, Mengji
    Host Genetic Determinants of Hepatitis B Virus Infection
    In: Frontiers in Genetics Jg. 10 (2019) S. 696
    ISSN: 1664-8021
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xu, Gang; Xia, Zhangchuan; Deng, Feiyan; Liu, Lin; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhu, Chengliang; Liu, Weiyong; Cheng, Zhikui; Zhu, Ying; Zhou, Li; Zhang, Yi; Lu, Mengji; Liu, Shi
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    • Abstracts

  • Zhenhua, Zhu; Trippler, Martin; Real, Catherine Isabell; Werner, Melanie; Kemper, Thekla; Baba, Hideo Andreas; Treckmann, Jürgen Walter; Paul, A.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji; Bröring, Ruth
    Hepatitis B virus entry in primary human hepatocytes initiates toll-like receptor 2-dependent immune signaling
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 793
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Anastasiou, Olympia E.; Westhaus, Sandra; Anspach, Marie Christine; Timmer, Lejla; Susser, Simone; Sarrazin, Christoph; Gerken, Guido; Keitel, Verena; Wedemeyer, Heiner; Lu, Mengji; Stindt, Jan; Ciesek, Sandra
    Sodium taurocholate cotransporting popypeptide variants modulate HDV entry according to their function as a bile acid transporter but do not influence the antiviral effect of Myrcludex-B
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 781
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, X.; Ge, J.; Huang, Z.; Sun, J.; Lu, Mengji; Hou, J.
    Expression and Function of Toll-Like Receptor 7 in Chronic Hepatitis B Patients Links to Antiviral Effect of PEG-IFN-A-2A Therapy
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S380 - S381
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, J.; Yang, D.; Lu, Mengji
    HBV Strengthens Intrahepatic Myeloid-Derived Cells Mediated T Cell Tolerance through TLR1/2 Induced Kupffer Cell Expansion and IL-10 Production
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S515
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Zhang, Z.; Trippler, M.; Real, C.; Werner, M.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji
    Hepatitis B virus activates toll-like receptor 2 signaling upon infection of primary human hepatocytes
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S394
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, J.; Xu, C.; Zheng, X.; Lu, Mengji; Yang, D.
    Increased TLR2 Expression in Peripheral CD4+T Cells Promotes TH17 Cells Responses and is Associated with Disease Aggravation of HBV-Related Acute-on-Chronic Liver Failure
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S307
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, X.; Liu, H.; Wang, B.; Ma, Z.; Zhang, J.; Yang, D.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Epigenetic control of Hepatitis B virus replication and farnesoid X receptor alpha expression by histone deacetylases 3
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Suppl. 2, S. S17
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, H.; Zhang, J.; Zhang, X.; Bleekmann, B.; Kemper, T.; Roggendorf, Michael; Dittmer, Ulf; Lu, Mengji
    Genomic analysis of the host response to hepatitis b virus infection
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S187
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Hepatitis B virus surface antigen suppresses innate and adaptive immune responses of murine and human liver cells
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S174
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Wu, J.; Zhang, E.; Zhang, X.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    TLR-3 dependent immunological properties of liver cells are controlled by anti-inflammatory cytokines through modulation of MIR-155 expression
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S302 - S303
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, J.; Jiang, M.; Ma, Z.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand stimulated mouse liver endothelial cells produce IL-12 and trigger CD8+ T-Cell immunity
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S311
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Ma, Z.; Zhang, E.; Zhang, X.; Liu, J.; Lin, Y.; Wu, J.; Kosinska, A.; Dittmer, Ulf; Roggendorf, Michael; Yang, D.; Lu, Mengji
    TLR2 ligand PAM3CSK4 inhibits peptide-induced deletion of CD8 T cells to viral antigens in mouse model
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S312
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Wu, J.; Chen, M.; Xia, Y.; Sun, C.; Lin, Y.; Wang, J.; Guo, Y.; Wang, B.; Song, J.; Lu, Mengji; Yang, D.
    The clearance of Hepatitis B virus (HBV) n hydrodynamik injection mouse model by polyinosinic-polycytidylic acid (POLYIC) treatment is dependent on interferon-gamma
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S319
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Meng, Z.; Zhang, E.; Zhang, X.; Kosinska, A.; Xu, Y.; Yang, D.; Zhou, T.; Mason, W.; Roggendorf, Michael; Lu, Mengji
    DNA vaccination induces WHS/CAG specific T Cell immune responses in the newly constructed WHV transgenic mouse model
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S441
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Wang, J. Z.; Wang, B. J.; Huang, S. M.; Wu, J.; Zhu, Z. N.; Zhu, B.; Ding, H. H.; Feng, X. M.; Yin, Y.; Roggendorf, Michael; Lu, Mengji; Yang, D. L.
    Immunosuppression modulates the course of hepatitis B virus (HBV) infection in hydrodynamic injection mouse model
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S127
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, X.; Ma, Z.; Wu, C.; Zhang, E.; Bröring, Ruth; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of HBV replication by cell cycle and differentiation related micrornas
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S448 - S449
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Schumann, A.; Kosinska, A.; Lu, Mengji; Johrden, L.; Wildner, O.; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects woodchucks from hepatitis D virus infection
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S439
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Xu, L.; Beckebaum, Susanne; Wu, G.; Zhang, X.; Lu, Mengji; Iacob, S.; Paul, Andreas; Gerken, Guido; Cicinnati, Vito R.;
    The putative tumor suppressor microrna-101 negatively regulates the polycomb group protein enhancer of zeste homolog 2 (EZH2) in human hepatocellular carcinoma cells
    46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011,
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S110
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Wu, J.; Zhang, E.; Meng, Z.; Trippler, M.; Bröring, Ruth; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    446 HCV/TLR3- dependent innate and adaptive immune functions of non-parenchymal liver cells are controlled by interleukin-10 and transforming growth factor beta
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S180
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, E.; Kosinska, A.; Zhang, X.; Meng, Z.; Xu, Y.; Yang, D.; Roggendorf, Michael; Lu, Mengji;
    637 Enhanced TH2 type immune response in DNA immunization by fusion of WCTLA-4 to woodchuck hepatitis core antigen
    International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver,
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S249
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Roggendorf, Michael; Ke, X.Y.; Yang, Y.; Yang, D.L.; Zhang, X.Y.; Meng, Z.J.; Kemper, T.; Wang, Q.J.; Lu, Mengji; Lu, L.;
    OL-022 The effect of double-stranded DNA on replication of hepatitis B virus and cellular signalling
    Fourth Ditan International Conference on Infectious Diseases - Changing Face of Infectious Diseases. 15-18 July 2010, Beijing,
    In: International Journal of Infectious Diseases Jg. 14 (2010) Nr. Suppl. 2, S. S10
    ISSN: 1878-3511; 1201-9712
    Online Volltext: dx.doi.org/ (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Liu, Jia; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Yang, Dongliang; Lu, Mengji
    Advanced Method for Isolation of Mouse Hepatocytes, Liver Sinusoidal Endothelial Cells, and Kupffer Cells
    In: Hepatitis B Virus: Methods and Protocols / Guo, Haitao; Cuconati, Andrea (Hrsg.) 2017, S. 249 - 258
    ISBN: 978-1-4939-6700-1
    Online Volltext: dx.doi.org/
  • Bauer, Dirk; Wasmuth, Susanne; Lu, Mengji; Heiligenhaus, Arnd
    Particle-mediated administration of plasmid DNA on corneas of BALB/c mice
    In: Biolistic DNA Delivery: Methods and Protocols / Sudowe, Stephan; Reske-Kunz, Angelika B. (Hrsg.) 2013, S. 215 - 220
    ISBN: 978-1-62703-109-7; 978-1-62703-110-3 ISSN: 1940-6029
    Online Volltext: dx.doi.org/
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, M.
    Protektion von Woodchucks gegen Woodchuckhepatitisvirus (WHV)-Infektion durch DNA-Immunisierung mit WHcAg- und WHsAg-exprimierenden Plasmiden.
    In: Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998, 1998, S. 30
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, M.
    Immunization of woodchucks with plasmids expressing Woodchuck Hepatitis Virus (WHV) core antigen and surface antigen confers protection from infection with WHV.
    In: Molecular Biology of Hepatitis B Viruses, Institut Pasteur, Paris. 21.-25.9.1997. 1997 O 62

    • Vorträge

  • Lu, Mengji; Hilken, Gero; Yang, D.; Roggendorf, Michael;
    Replikation von Deletionsmutanten des Woodchuck Hepatitis Virus (WHV) in primären Woodchuck Hepatitis Kulturen und in vivo nach einer Übertragung
    38. Tagung der GV-SOLAS, September 2000, Essen,
    (2000)