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Prof. Dr. rer. nat. Mengji Lu

Institut für Virologie der Medizinischen Fakultät

Anschrift
Virchowstr. 179 / Robert-Koch-Haus
45147 Essen
Telefon
+49 201 723 3530
E-Mail
mengji.lu@uni-due.de
Webseite
http://www.uni-due.de/virologie/res_lu_en.html

Funktionen

  • Universitätsprofessor/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Wang, Jun; Xiao, Nan; Zhu, Zhengnong; Qiao, Haiyan; Zhao, Fang; Zhang, Lukun; Gou, Jizhou; Lu, Mengji; He, Yun; Lu, Hongzhou; Li, Qian
    Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion
    In: Signal Transduction and Targeted Therapy Jg. 10 (2025) Nr. 1, 23
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhu, Dan; Du, Yanqin; Zhao, Mengxiao; Ablikim, Dilhumare; Huang, Hongming; Pan, Wen; Zeng, Xiaoqing; Xu, Chunli; Lu, Mengji; Sutter, Kathrin; Dittmer, Ulf; Zheng, Xin; Yang, Dongliang; Liu, Jia
    Functional B cell deficiency promotes intrahepatic HBV replication and impairs the development of anti-HBV T cell responses
    In: Hepatology International Jg. 19 (2025) Nr. 1, S. 93 - 105
    Online Volltext: dx.doi.org/
  • Deng, Yingying; Zheng, Jiaxin; Li, Fahong; Zou, Hecun; Tian, Shijun; Zhao, Zhenyu; Zeng, Huaqing; Zhai, Yongzhen; Deng, Wanyu; Zhang, Jiming; Lu, Mengji; Jia, Bei; Lin, Yong
    Hepatocyte-Enriched miRNA-193b-3p Promotes Hepatitis B Virus Replication by Dual Activation of Viral Core Promoter Activity and Autophagy Induction by Targeting IGF-1R
    In: Journal of Medical Virology Jg. 97 (2025) Nr. 4, e70330
    Online Volltext: dx.doi.org/
  • Yang, Li; Gong, Ying; Liu, Feifei; Chen, Wuhong; Wang, Xinran; Long, Guozhang; Li, Heng; Xiao, Fuling; Lu, Mengji; Hu, Youhong; Tong, Xiankun; Zuo, Jianping
    A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
    In: Antiviral Research Jg. 221 (2024) 105763
    Online Volltext: dx.doi.org/
  • Wang, Jun; Li, Qian; Qiu, Yuanwang; Kitanovski, Simo; Wang, Chen; Zhang, Chenxia; Li, Fahong; Li, Xiaoguang; Zhang, Zhenfeng; Huang, Lihua; Zhang, Jiming; Hoffmann, Daniel; Lu, Mengji; Lu, Hongzhou
    Cell-type-specific expression analysis of liver transcriptomics with clinical parameters to decipher the cause of intrahepatic inflammation in chronic hepatitis B
    In: iMeta Jg. 3 (2024) Nr. 4, e221
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Cheng; Gou, Jizhou; Kitanovski, Simo; Tang, XiangYi; Cai, Yixuan; Zhang, Chenxia; Zhang, Xiling; Zhang, Zhenfeng; Qiu, Yuanwang; Zhao, Fang; Lu, Mengji; He, Yun; Wang, Jun; Lu, Hongzhou
    Deciphering lung granulomas in HIV & TB co-infection : unveiling macrophages aggregation with IL6R/STAT3 activation
    In: Emerging Microbes & Infections Jg. 13 (2024) Nr. 1, 2366359
    Online Volltext: dx.doi.org/ (Open Access)
  • Song, Jingjiao; Sun, Xiliang; Zhou, Yun; Li, Sheng; Wu, Jun; Yang, Lu; Zhou, Di; Yang, Yan; Liu, Anding; Lu, Mengji; Roggendorf, Michael; Qin, Li; Yang, Dongliang
    Early application of IFNγ mediated the persistence of HBV in an HBV mouse model
    In: Antiviral Research Jg. 225 (2024) 105872
    Online Volltext: dx.doi.org/
  • Liang, Yaojie; Luo, Xufeng; Schefczyk, Stefan; Muungani, Lorraine T.; Deng, Hui; Wang, Baoju; Baba, Hideo Andreas; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut; Bröring, Ruth
    Hepatitis B surface antigen expression impairs endoplasmic reticulum stress-related autophagic flux by decreasing LAMP2
    In: JHEP Reports Jg. 6 (2024) Nr. 4, 101012
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Jia; Lin, Yong; Wang, Xueyu; Lu, Mengji
    Interconnection of cellular autophagy and endosomal vesicle trafficking and its role in hepatitis B virus replication and release
    In: Virologica Sinica Jg. 39 (2024) Nr. 1, S. 24 - 30
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Shilei; Deng, Ke-Qiong; Lu, Chengbo; Fu, Xin; Zhu, Qingmei; Wan, Shiqi; Zhang, Lin; Huang, Yu; Nie, Longyu; Cai, Huanhuan; Wang, Qiming; Zeng, Hao; Zhang, Yufeng; Wang, Fubing; Ren, Hong; Chen, Yu; Yan, Huan; Xu, Ke; Zhou, Li; Lu, Mengji; Zhu, Ying; Liu, Shi; Lu, Zhibing
    Interleukin-6 classic and trans-signaling utilize glucose metabolism reprogramming to achieve anti- or pro-inflammatory effects
    In: Metabolism Jg. 155 (2024) 155832
    Online Volltext: dx.doi.org/
  • Ye, Jianyu; Li, Fahong; Hua, Ting; Ma, Kewei; Wang, Jinyu; Zhao, Zixin; Yang, Zhongning; Luo, Chen; Jia, Ruohan; Li, Yaming; Hao, Menghan; Wu, Jian; Lu, Mengji; Yuan, Zhenghong; Zhang, Jiming; Chen, Jieliang
    Liver mechanosignaling as a natural anti-hepatitis B virus mechanism
    In: Nature Communications Jg. 15 (2024) Nr. 1, S. 8375
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Yanqin; Sun, Hang; Bhattacharjee, Sonakshi; Birkmann, Alexander; Dittmer, Ulf; Lu, Mengji
    TLR9 dependent activation by inactivated parapoxvirus ovis (iPPVO) in murine bone marrow-derived dendritic cells is associated with specific strain-dependent dendritic cell subsets
    In: Journal of Innate Immunity Jg. 16 (2024) Nr. 1, S. 354 - 366
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Qin; Liu, Yanan; Luo, Jinzhuo; Yang, Shangqing; Wang, Lu; Lu, Yinping; Feng, Xuemei; Yang, Xuecheng; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Zheng, Xin; Yang, Dongliang; Liu, Jia
    A systematic comparison reveals dynamic differences in early adaptive immune responses of acute-resolving versus chronic HBV replication
    In: Journal of Medical Virology Jg. 95 (2023) Nr. 3, e28670
    Online Volltext: dx.doi.org/ (Open Access)
  • Yang, Lu; Zhou, Di; Martin, Kächele; Wu, Jun; Chen, Mingfa; Lu, Mengji; Yang, Dongliang; Protzer, Ulrike; Roggendorf, Michael; Song, Jingjiao
    Aborted infection of human sodium taurocholate cotransporting polypeptide (hNTCP) expressing woodchuck hepatocytes with hepatitis B virus (HBV)
    In: Virus Genes Jg. 59 (2023) S. 823 - 830
    Online Volltext: dx.doi.org/
  • Zhao, Zhenyu; Wei, Zhen; Zheng, Jiaxin; Li, Zhihong; Zou, Hecun; Wen, Xiang; Li, Fahong; Wang, Xueyu; Huang, Qian; Zeng, Huaqing; Fan, Hui; Cai, Xuefei; Zhang, Jiming; Jia, Bei; Huang, Ailong; Lu, Mengji; Lin, Yong
    Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways
    In: Emerging Microbes & Infections Jg. 12 (2023) Nr. 2, 2261556
    Online Volltext: dx.doi.org/ (Open Access)
  • Yu, Jie; Shen, Zhongliang; Chen, Shiqi; Liu, Hongyan; Du, Zunguo; Mao, Richeng; Wang, Jinyu; Zhang, Yongmei; Zhu, Haoxiang; Yang, Sisi; Li, Jing; Wu, Jingwen; Dong, Minhui; Zhu, Mengqi; Huang, Yuxian; Li, Jianhua; Yuan, Zhenghong; Xie, Youhua; Lu, Mengji; Zhang, Jiming
    Inhibition of HBV replication by EVA1A via enhancing cellular degradation of HBV components and its potential therapeutic application
    In: Antiviral Research Jg. 216 (2023) 105643
    Online Volltext: dx.doi.org/
  • Zheng, Jiaxin; Deng, Yingying; Wei, Zhen; Zou, Hecun; Wen, Xiang; Cai, Jia; Zhang, Shujun; Jia, Bei; Lu, Mengji; Lu, Kefeng; Lin, Yong
    Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions
    In: Antiviral Research Jg. 213 (2023) 105601
    Online Volltext: dx.doi.org/ (Open Access)
  • He, Qiao-qiao; Huang, Yu; Nie, Longyu; Ren, Sheng; Xu, Gang; Deng, Feiyan; Cheng, Zhikui; Zuo, Qi; Zhang, Lin; Cai, Huanhuan; Wang, Qiming; Wang, Fubing; Ren, Hong; Yan, Huan; Xu, Ke; Zhou, Li; Lu, Mengji; Lu, Zhibing; Zhu, Ying; Liu, Shi
    MAVS integrates glucose metabolism and RIG-I-like receptor signaling
    In: Nature Communications Jg. 14 (2023) Nr. 1, 5343
    Online Volltext: dx.doi.org/ (Open Access)
  • Westmeier, Jaana; Brochtrup, Annika; Paniskaki, Krystallenia; Karakoese, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Limmer, Andreas; Mittermüller, Daniela; Liu, Jia; Zheng, Xin; Koval, Tetiana; Kaidashev, Igor; Berger, Marc Moritz; Herbstreit, Frank; Brenner, Thorsten; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients
    In: Frontiers in Immunology Jg. 14 (2023) 1236374
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Jinyu; Zhang, Xueyun; Han, Jiajia; Zhou, Pu; Yu, Xueping; Shen, Zhongliang; Mao, Richeng; Lu, Mengji; Huang, Yuxian; Zhang, Jiming
    MicroRNA-124 expression in Kupffer cells modulates liver injury by targeting IL-6/STAT3 signaling
    In: Antiviral Research Jg. 211 (2023) 105510
    Online Volltext: dx.doi.org/
  • Xie, Zhanglian; Shen, Sheng; Huang, Kuiyuan; Wang, Weibin; Liu, Ziying; Zhang, Haixing; Lu, Mengji; Sun, Jian; Hou, Jinlin; Liu, Hongyan; Guo, Haitao; Zhang, Xiaoyong
    Mitochondrial HIGD1A inhibits hepatitis B virus transcription and replication through the cellular PNKD-NF-κB-NR2F1 nexus
    In: Journal of Medical Virology Jg. 95 (2023) Nr. 4, e28749
    Online Volltext: dx.doi.org/
  • Luo, Xufeng; Zhang, Rui; Schefczyk, Stefan; Liang, Yaojie; Lin, Shu S.; Liu, Shi; Baba, Hideo Andreas; Lange, Christian M.; Wedemeyer, Heiner; Lu, Mengji; Bröring, Ruth
    Nuclear translocation of YAP drives BMI1-associated hepatocarcinogenesis in hepatitis B virus infection
    In: Liver International Jg. 43 (2023) Nr. 9, S. 2002 - 2016
    Online Volltext: dx.doi.org/ (Open Access)
  • Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Trippler, Martin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut; Bröring, Ruth
    Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo
    In: Viruses Jg. 15 (2023) Nr. 5, 1203
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Liu, Jing; Deng, Hui; Yang, Xuecheng; Wang, Hua; Feng, Xuemei; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Wang, Baoju; Yang, Dongliang; Zheng, Xin; Liu, Jia
    SARS-CoV-2-specific T cell responses wane profoundly in convalescent individuals 10 months after primary infection
    In: Virologica Sinica Jg. 38 (2023) Nr. 4, S. 606 - 619
    Online Volltext: dx.doi.org/ (Open Access)
  • Karakoese, Zehra; Le-Trilling, Vu Thuy Khanh; Schuhenn, Jonas; Francois, Sandra; Lu, Mengji; Liu, Jia; Trilling, Mirko; Hoffmann, Daniel; Dittmer, Ulf; Sutter, Kathrin
    Targeted mutations in IFNα2 improve its antiviral activity against various viruses
    In: mBio Jg. 14 (2023) Nr. 6, e02357-23
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Hasenberg, Mike; Walkenfort, Bernd; Trippler, Martin; Schuhenn, Jonas; Sutter, Kathrin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut H.; Broering, Ruth
    Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis
    In: Scientific Reports Jg. 13 (2023) Nr. 1, 22829
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhang, Yue; Yan, Hu; Li, Xian; Zhou, Dihan; Zhong, Maohua; Yang, Jingyi; Zhao, Bali; Fan, Xuxu; Fan, Jun; Shu, Jiayi; Lu, Mengji; Jin, Xia; Zhang, Ejuan; Yan, Huimin
    A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus
    In: PLoS Neglected Tropical Diseases Jg. 16 (2022) Nr. 1, e0010149
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Xueyu; Wei, Zhiqiang; Lan, Tingyu; He, Yulin; Cheng, Bin; Li, Ruimin; Chen, Hongxia; Li, Fahong; Liu, Guohua; Jiang, Bin; Lin, Yong; Lu, Mengji; Meng, Zhongji
    CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation
    In: Autophagy Jg. 18 (2022) Nr. 2, S. 357 - 374
    Online Volltext: dx.doi.org/ (Open Access)
  • Zheng, Jiaxin; Deng, Yingying; Zhao, Zhenyu; Mao, Binli; Lu, Mengji; Lin, Yong; Huang, Ailong
    Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects
    In: Cellular & Molecular Immunology Jg. 19 (2022) Nr. 2, S. 150 - 157
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Ejuan; Ma, Zhiyong; Lu, Mengji
    Contribution of T- and B-cell intrinsic toll-like receptors to the adaptive immune response in viral infectious diseases
    In: Cellular and Molecular Life Sciences - CMLS Jg. 79 (2022) Nr. 11, 547
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Xueyu; Wei, Zhiqiang; Cheng, Bin; Li, Jia; He, Yulin; Lan, Tingyu; Kemper, Thekla; Lin, Yong; Jiang, Bin; Jiang, Yongfang; Meng, Zhongji; Lu, Mengji
    Endoplasmic reticulum stress promotes HBV production by enhancing use of the autophagosome/multivesicular body axis
    In: Hepatology Jg. 75 (2022) Nr. 2, S. 438 - 454
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Shuhui; Zhao, Kaitao; Su, Xi; Gao, Xiaoxiao; Yao, Yongxuan; Kong, Ranran; Wang, Yun; Wu, Chunchen; Lu, Mengji; Chen, Xinwen; Pei, Rongjuan
    Enhanced host immune responses in presence of HCV facilitate HBV clearance in coinfection
    In: Virologica Sinica Jg. 37 (2022) Nr. 3, S. 408 - 417
    Online Volltext: dx.doi.org/ (Open Access)
  • Xia, Jianbo; Cao, Liang; Zhao, Zhenyu; Deng, Yingying; Lu, Mengji; Wu, Chunchen; Lin, Yong
    HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy
    In: Genes & Diseases Jg. 9 (2022) Nr. 6, S. 1401 - 1404
    Online Volltext: dx.doi.org/ (Open Access)
  • Xie, Xiaohong; Luo, Jinzhuo; Zhu, Dan; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Mengji; Zheng, Xin; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    HBeAg Is Indispensable for Inducing Liver Sinusoidal Endothelial Cell Activation by Hepatitis B Virus
    In: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022) 797915
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Fahong; Deng, Yingying; Zhang, Shenyan; Zhu, Beidi; Wang, Jun; Wang, Jinyu; Wang, Xueyu; Zhao, Zhenyu; Deng, Wanyu; Mao, Richeng; Shen, Zhongliang; Chen, Jieliang; Bröring, Ruth; Lin, Yong; Lu, Mengji; Zhang, Jiming
    Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 616 - 628
    Online Volltext: dx.doi.org/ (Open Access)
  • Podschwadt, Philip; Malyshkina, Anna; Windmann, Sonja; Papadamakis, Athanasios; Kerkmann, Leonie; Lapuente, Dennis; Tenbusch, Matthias; Lu, Mengji; Schindler, Michael; Lang, Karl Sebastian; Hansen, Wiebke; Bayer, Wibke
    Immune suppression of vaccine-induced CD8⁺ T cell-responses by gamma retrovirus envelope is mediated by interleukin-10 producing CD4⁺ T cells
    In: Frontiers in Immunology Jg. 13 (2022) 934399
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Jia; Kemper, Thekla; Bröring, Ruth; Chen, Jieliang; Yuan, Zhenghong; Wang, Xueyu; Lu, Mengji
    Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication
    In: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022) 804011
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Wang, Kai; Mennerich, Denise; Hu, Jie; Zhao, Zhenyu; Zheng, Jiaxin; Deng, Yingying; Katschinski, Benjamin; Xu, Shilei; Zhang, Guiji; Cai, Xuefei; Hu, Yuan; Wang, Jianwei; Lu, Mengji; Huang, Ailong; Tang, Ni; Trilling, Mirko; Lin, Yong
    Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 483 - 497
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Du, Yanqin; Wu, Jun; Liu, Jia; Zheng, Xin; Yang, Dongliang; Lu, Mengji
    Toll-like receptor-mediated innate immunity orchestrates adaptive immune responses in HBV infection
    In: Frontiers in Immunology Jg. 13 (2022) 965018
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, Jia; Yang, Xuecheng; Wang, Hua; Li, Ziwei; Deng, Hui; Liu, Jing; Xiong, Shue; He, Junyi; Feng, Xuemei; Guo, Chunxia; Wang, Weixian; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Senff, Tina; Menne, Christopher; Timm, Jörg; Zhang, Yanfang; Deng, Fei; Lu, Yinping; Wu, Jun; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Wang, Baoju; Zheng, Xin
    Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairment
    In: mBio Jg. 12 (2021) Nr. 2, S. e00085 - 21
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Zhou, Xueshi; Lu, Hongzhou; Lu, Mengji; Huang, Lihua
    Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver Disease
    In: Frontiers in Medicine Jg. 8 (2021) 582620
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Deng, Hui; Wang, Hua; Feng, Xuemei; Quan, Xufeng; Wang, Xiaoyan; Li, Sumeng; Lu, Sihong; Yang, Xuecheng; Wang, Baoju; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Zheng, Xin; Liu, Jia
    Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World Setting
    In: Frontiers in Immunology Jg. 12 (2021) 802858
    Online Volltext: dx.doi.org/ (Open Access)
  • Bröring, Ruth; Luo, Xufeng; Liu, Jia; Lu, Mengji
    Controversial: Early Innate Responses to Hepatitis B Virus Infection, an Explanation for Viral Persistence?
    In: Virologica Sinica Jg. 36 (2021) Nr. 1, S. 163 - 166
    Online Volltext: dx.doi.org/ (Open Access)
  • Xiang, Tiandan; Liang, Boyun; Fang, Yaohui; Lu, Sihong; Li, Sumeng; Wang, Hua; Li, Huadong; Yang, Xiaoli; Shen, Shu; Zhu, Bin; Wang, Baoju; Wu, Jun; Liu, Jia; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Trilling, Mirko; Deng, Fei; Zheng, Xin
    Declining Levels of Neutralizing Antibodies Against SARS-CoV-2 in Convalescent COVID-19 Patients One Year Post Symptom Onset
    In: Frontiers in Immunology Jg. 12 (2021) 708523
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Du, Yanqin; Yang, Xiaoli; Li, Jia; Sokolova, Viktoriya; Zou, Shi; Han, Meihong; Yan, Hu; Wey, Karolin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Epple, Matthias; Wu, Jun
    Delivery of toll-like receptor 3 ligand poly(I:C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect in a mouse model
    In: Acta Biomaterialia Jg. 133 (2021) S. 297 - 307
    Online Volltext: dx.doi.org/
  • Chen, Jieliang; Li, Yaming; Lai, Fritz; Wang, Yang; Sutter, Kathrin; Dittmer, Ulf; Ye, Jianyu; Zai, Wenjing; Liu, Min; Shen, Fang; Wu, Min; Hu, Kongying; Li, Baocun; Lu, Mengji; Zhang, Xiaonan; Zhang, Jiming; Li, Jianhua; Chen, Qingfeng; Yuan, Zhenghong
    Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ Signaling
    In: Hepatology Jg. 73 (2021) Nr. 2, S. 486 - 502
    Online Volltext: dx.doi.org/
  • Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Buitrago-Molina, Laura Elisa; Lu, Mengji; Meyer, Hemmo; Tong, Chun-Kit
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
    In: Autophagy Jg. 17 (2021) Nr. 1, S. 1 - 382
    Online Volltext: dx.doi.org/ (Open Access)
  • Xie, Xiaohong; Luo, Jinzhuo; Bröring, Ruth; Zhu, Dan; Zhou, Wenqing; Lu, Mengji; Zheng, Xin; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance
    In: Cellular & Molecular Immunology Jg. 18 (2021) Nr. 11, S. 2572 - 2574
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Islam, Heba; Kirschning, Carsten Jürgen; Lu, Hongzhou; Hoffmann, Daniel; Dittmer, Ulf; Lu, Mengji
    Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis
    In: Cell Death and Disease Jg. 12 (2021) Nr. 1, 34
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhou, Li; He, Rui; Fang, Peining; Li, Mengqi; Yu, Haisheng; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Lin, Yong; Zhang, Rui; Trilling, Mirko; Bröring, Ruth; Lu, Mengji; Zhu, Ying; Liu, Shi
    Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 98
    Online Volltext: dx.doi.org/ (Open Access)
  • Luo, Xufeng; Zhang, Rui; Lu, Mengji; Liu, Shi; Baba, Hideo Andrea; Gerken, Guido; Wedemeyer, Heiner; Bröring, Ruth
    Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 12 (2021) 684424
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Du, Yanqin; Bröring, Ruth; Li, Xiaoran; Zhang, Xiaoyong; Liu, Jia; Yang, Dongliang; Lu, Mengji
    In Vivo Mouse Models for Hepatitis B Virus Infection and Their Application
    In: Frontiers in Immunology Jg. 12 (2021) 766534
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xiong, Shue; Zhu, Dan; Liang, Boyun; Li, Mingyue; Pan, Wen; He, Junyi; Wang, Hua; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Liu, Di; Yang, Dongliang; Liu, Jia; Zheng, Xin
    Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss
    In: eBioMedicine Jg. 69 (2021) 103464
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Yanqin; Yan, Hu; Zou, Shi; Khera, Tanvi; Li, Jia; Han, Meihong; Yang, Xiaoli; Wang, Baoju; Liu, Jia; Sun, Shuilin; Zheng, Xin; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang; Wedemeyer, Heiner; Wu, Jun
    Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model
    In: Hepatology Communications Jg. 5 (2021) Nr. 5, S. 865 - 881
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    Serum LBP levels reflect the impaired synthetic capacity of the remnant liver after partial hepatectomy in rats
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    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Montag, Mario; Jiang, Min; Lu, Mengji; Sowa, Jan-Peter; Kleinehr, Kathrin; Gerken, Guido; Schlaak, Jörg Friedrich
    Corticosteroids shift the Toll-like receptor response pattern of primary-isolated murine liver cells from an inflammatory to an anti-inflammatory state
    In: International Immunology Jg. 23 (2011) Nr. 9, S. 537 - 544
    Online Volltext: dx.doi.org/
  • Yin, Ying; Wu, Chunchen; Song, Jingjiao; Wang, Junzhong; Zhang, Ejuan; Liu, Hongyan; Yang, Dongliang; Chen, Xinwen; Lu, Mengji; Xu, Yang
    DNA Immunization with Fusion of CTLA-4 to Hepatitis B Virus (HBV) Core Protein Enhanced Th2 Type Responses and Cleared HBV with an Accelerated Kinetic
    In: PLoS ONE Jg. 6 (2011) Nr. 7, S. 0022524
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Zhenhuan; Li, Lei; Zhao, Xiping; Glebe, Dieter; Bremer, Corinna M.; Zhang, Zheng Mao; Tian, Yong Jun; Wang, Bao Ju; Yang, Yinke; Gerlich, Wolfram Hubert; Roggendorf, Michael; Li, Xu; Lu, Mengji; Yang, Dong Liang
    Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance
    In: Journal of Viral Hepatitis Jg. 18 (2011) Nr. 6, S. 424 - 433
    Online Volltext: dx.doi.org/
  • Wang, Bao-Ju; Tian, Yong-Jun; Meng, Zhong-Ji; Jiang, Min; Wei, Bo-Qing; Tao, Yuan-Qing; Fan, Wei; Li, An-Yi; Bao, Jun-Jie; Li, Xin-Yu; Zhang, Zheng-Mao; Wang, Zhong-Dong; Wang, Hu; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Establishing a new animal model for hepadnaviral infection : Susceptibility of Chinese Marmota-species to woodchuck hepatitis virus infection
    In: Journal of General Virology Jg. 92 (2011) Nr. 3, S. 681 - 691
    Online Volltext: dx.doi.org/ (Open Access)
  • Pei, Rongjuan; Chen, Honghe; Lu, Lu; Zhu, Wandi; Beckebaum, Susanne; Cicinnati, Vito; Lu, Mengji; Chen, Xinwen
    Hepatitis C virus infection induces the expression of amphiregulin, a factor related to the activation of cellular survival pathways and required for efficient viral assembly
    In: Journal of General Virology Jg. 92 (2011) Nr. 10, S. 2237 - 2248
    Online Volltext: dx.doi.org/
  • Wang, Bao-Ju; Bao, Jun-Jie; Wang, Jun-Zhong; Wang, Yang; Jiang, Min; Xing, Ming-You; Zhang, Wan-Guang; Qi, Jun-Ying; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma
    In: World Journal of Gastroenterology Jg. 17 (2011) Nr. 28, S. 3322 - 3329
    Online Volltext: dx.doi.org/
  • Liu, Min; Hao, Youhua; Ding, Honghui; Yang, Dongliang; Lu, Mengji
    Interleukin-10 is expressed in HepG2.2.15 cells and regulated by STAT1 pathway
    In: Journal of Huazhong University of Science and Technology (Medical Sciences) Jg. 31 (2011) Nr. 5, S. 625 - 631
    Online Volltext: dx.doi.org/
  • Zhang, Xiaoyong; Zhang, Ejuan; Ma, Zhiyong; Pei, Rongjuan; Jiang, Min; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1
    In: Hepatology Jg. 53 (2011) Nr. 5, S. 1476 - 1485
    Online Volltext: dx.doi.org/ (Open Access)
  • Bröring, Ruth; Lu, Mengji; Schlaak, Jörg Friedrich; Schlaak, Joerg F.
    Role of Toll-like receptors in liver health and disease
    In: Clinical Science Jg. 121 (2011) Nr. 10, S. 415 - 426
    Online Volltext: dx.doi.org/
  • Xu, Yang; Köck, Josef; Lu, Yinping; Yang, Dongliang; Lu, Mengji; Zhao, Xiping
    Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 34 (2011) Nr. 4, S. 361 - 368
    Online Volltext: dx.doi.org/
  • Zhang, Ejuan; Zhang, Xiaoyong; Liu, Jia; Wang, Baoju; Tian, Yongjun; Kosinska, Anna D.; Ma, Zhiyong; Xu, Yang; Dittmer, Ulf; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    The Expression of PD-1 Ligands and Their Involvement in Regulation of T Cell Functions in Acute and Chronic Woodchuck Hepatitis Virus Infection
    In: PLoS ONE Jg. 6 (2011) Nr. 10, S. 0026196
    Online Volltext: dx.doi.org/ (Open Access)
  • Zelinskyy, Gennadiy; Myers, Lara; Dietze, Kirsten; Gibbert, Kathrin; Roggendorf, Michael; Liu, Jia; Lu, Mengji; Kraft, Anke R.; Teichgräber, Volker; Hasenkrug, Kim J.; Dittmer, Ulf
    Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication
    In: The Journal of Immunology (JI) Jg. 187 (2011) Nr. 7, S. 3730 - 3737
    Online Volltext: dx.doi.org/
  • Zhang, X.; Zhang, E.; Meng, Z.; Ma, Z.; Schlaak, Jörg Friedrich; Lu, Mengji
    110 Modulation of HBV replication and cellular gene expression by microrna-1
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S49 - S50
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Wu, J.; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    627 HBV suppresses TLR signaling and the crosstalk to the adaptive immune system in murine and human cells
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S246
    Online Volltext: dx.doi.org/
  • Liu, Jia; Hu, Bin; Yang, Yan; Ma, Zhiyong; Yu, Yuan; Liu, Shenpei; Wang, Baoju; Zhao, Xiping; Lu, Mengji; Yang, Dongliang
    A new splice variant of the major subunit of human asialoglycoprotein receptor encodes a secreted form in hepatocytes
    In: PLoS ONE Jg. 5 (2010) Nr. 9,
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Chunchen; Zhang, Xiaoyong; Tian, Zhang; Song, Jianhua; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen; Tian, Y.
    Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
    In: Journal of General Virology Jg. 91 (2010) Nr. 2, S. 483 - 492
    Online Volltext: dx.doi.org/
  • Liu, Jia; Yang, Yan; Hu, Bin; Ma, Zhi-Yong; Huang, Hong-Ping; Yu, Yuan; Liu, Shen-Pei; Lu, Mengji; Yang, Dong-Liang
    Development of HBsAg-binding aptamers that bind HepG2.2.15 cells via HBV surface antigen
    In: Virologica Sinica Jg. 25 (2010) Nr. 1, S. 27 - 35
    Online Volltext: dx.doi.org/
  • Hu, Bin; Yang, Yan; Liu, Jia; Ma, Zhiyong; Huang, Hongping; Liu, Shenpei; Yu, Yuan; Hao, Youhua; Wang, Baoju; Lu, Mengji; Yang, Dongliang
    Establishment of a functional cell line expressing both subunits of H1a and H2c of human hepatocyte surface molecule ASGPR
    In: Journal of Huazhong University of Science and Technology (Medical Sciences) Jg. 30 (2010) Nr. 5, S. 556 - 561
    Online Volltext: dx.doi.org/
  • Li, Yanmei; Chen, Jizheng; Wu, Chunchen; Wang, Linding; Lu, Mengji; Chen, Xinwen
    Hepatitis B virus/hepatitis C virus upregulate angiopoietin-2 expression through mitogen-activated protein kinase pathway
    In: Hepatology Research Jg. 40 (2010) Nr. 10, S. 1022 - 1033
    Online Volltext: dx.doi.org/
  • Shen, Qingli; Cicinnati, Vito; Zhang, Xiaoyong; Iacob, Speranta; Weber, Frank; Sotiropoulos, Georgios; Radtke, Arnold; Lu, Mengji; Paul, Andreas; Gerken, Guido; Beckebaum, Susanne
    Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
    In: Molecular Cancer Jg. 9 (2010) 227
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhu, Wenbo; Chang, Yanzi; Wu, Chunchen; Han, Qingxia; Pei, Rongjuan; Lu, Mengji; Chen, Xinwen
    The Wild-Type Hepatitis C Virus Core Inhibits Initiation of Antigen-Specific T- and B-Cell Immune Responses in BALB/c Mice
    In: Clinical and Vaccine Immunology Jg. 17 (2010) Nr. 7, S. 1139 - 1147
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Zhang, Xiaozhen; Kottilil, Shyam; Trippler, Martin; Jiang, Min; Lu, Mengji; Gerken, Guido; Schlaak, Jörg Friedrich
    The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response
    In: Gut Jg. 59 (2010) Nr. 8, S. 1111 - 1119
    Online Volltext: dx.doi.org/
  • Roggendorf, Michael; Yang, D.; Lu, Mengji
    The woodchuck : A model for therapeutic vaccination against hepadnaviral infection
    In: Pathologie - Biologie Jg. 58 (2010) Nr. 4, S. 308 - 314
    Online Volltext: dx.doi.org/
  • Wu, Jun; Meng, Zhongji; Jiang, Min; Zhang, Ejuan; Trippler, Martin; Bröring, Ruth; Bucchi, Agnes; Krux, Frank; Dittmer, Ulf; Yang, Dongliang; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific
    In: Immunology Jg. 129 (2010) Nr. 3, S. 363 - 374
    Online Volltext: dx.doi.org/
  • Lu, Mengji; Viazov, Sergey; Dittmer, Ulf; Roggendorf, Michael; aus dem Siepen, Marc
    Chronische Infektionen : ein Versagen des Immunsystems
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 34 - 47
    Online Volltext; Online Volltext (Open Access)
  • Lu, M.; Isogawa, M.; Hilken, Gero
    Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune response in mice and woodchucks.
    In: (J. Virol.) Jg. 79 (2005) Nr. 10, S. 6368 - 6376
  • Dahmen, Uta; Dirsch, Olaf; Li, Jun; Fiedler, Melanie; Lu, Mengji; Rispeter, Kai; Picucci, Martha; Broelsch, Christoph E.; Roggendorf, Michael
    Adoptive transfer of immunity : A new strategy to interfere with severe hepatitis virus reinfection after woodchuck liver transplantation
    In: Transplantation Jg. 77 (2004) Nr. 7, S. 965 - 972
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Rödicker, Florian; Salucci, Valentina; Lu, Mengji; Aurisicchio, Luigi; Dahmen, Uta; Jun, Li; Dirsch, Olaf; Pützer, Brigitte M.; Palombo, Fabio; Roggendorf, Michael
    Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-α) and IFN-γ : IFN-α but not IFN-γ reduces woodchuck hepatitis virus replication in chronic infection in vivo
    In: Journal of Virology Jg. 78 (2004) Nr. 18, S. 10111 - 10121
    Online Volltext: dx.doi.org/ (Open Access)
  • Zeng, X.; Weinberger, K.M.; Gehrke, R.; Isogawa, M.; Hilken, Gero; Kemper, T.; Xu, Y.; Yang, D.; Jilg, W.; Roggendorf, Michael; Lu, M.
    Mutant hepatitis B virus surface antigen (HbsAg) are immunogenic but may have a change specificity
    In: Virology Jg. 329 (2004) S. 454 - 464
  • Dahmen, Uta; Li, Jun; Dirsch, Olaf; Fiedler, Melanie; Lu, Mengji; Roggendorf, Michael; Broelsch, Christoph Erich
    A new model of hepatitis B virus reinfection : Liver transplantation in the woodchuck
    In: Transplantation Jg. 74 (2002) Nr. 3, S. 373 - 380
    Online Volltext: dx.doi.org/
  • Lu, M.; Lohrengel, B.; Hilken, Gero; Kemper, T.; Roggendorf, Michael
    Woodchuck gamma interferon upregulates major histocompartibility complex class I transcription but is unable to deplete woodchuck hepatitis virus replication intermediatesand RNAs in persistently infected woodchuck primary hepatocytes
    In: Journal of Virology Jg. 76 (2002) Nr. 1, S. 58 - 67
    Online Volltext: dx.doi.org/
  • Haupt, Katharina; Siegel, F.; Lu, M.; Yang, D.; Hilken, Gero; Mann, K.; Roggendorf, Michael; Saller, B.
    Induction of a cellular and humoral Immune response against preprocalcitonin by genetic immunization : A potential new treatment for medullary thyroid carcinoma
    In: Endocrinology Jg. 142 (2001) Nr. 3, S. 1017 - 1023
    Online Volltext: dx.doi.org/
  • Lu, M.; Hilken, Gero; Dongliang, Y.; Kemper, T.; Roggendorf, Michael
    Replication of naturally occurring Woodchuck Hepatitis Virus : Deletion Mutants in primary hepatocytes cultures and after transmission to naive woodchucks
    In: Journal of Virology Jg. 75 (2001) Nr. 8, S. 3811 - 3818
    Online Volltext: dx.doi.org/
  • Lu, Mengji; Hilken, Gero; Kruppenbacher, Johannes; Reimann, Jörg; Roggendorf, Michael
    Immunization of Woodchucks with Plasmids Expressing Woodchuck Hepatitis Virus (WHV) Core Antigen and Surface Antigen Suppresses WHV Infection
    In: Journal of Virology Jg. 73 (1999) Nr. 1, S. 281 - 289
    Online Volltext: dx.doi.org/ (Open Access)

    • Vorworte / Nachworte

  • Meng, Zhongji; Liu, Jia; Kosinska, Anna D.; Lu, Mengji
    Editorial: Targeting the Immune System to Treat Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 13 (2022) 868616
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Zhenhua, Zhu; Trippler, Martin; Real, Catherine Isabell; Werner, Melanie; Kemper, Thekla; Baba, Hideo Andreas; Treckmann, Jürgen-Walter; Paul, A.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji; Bröring, Ruth
    Hepatitis B virus entry in primary human hepatocytes initiates toll-like receptor 2-dependent immune signaling
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 793
    Online Volltext: dx.doi.org/
  • Anastasiou, Olympia E.; Westhaus, Sandra; Anspach, Marie Christine; Timmer, Lejla; Susser, Simone; Sarrazin, Christoph; Gerken, Guido; Keitel, Verena; Wedemeyer, Heiner; Lu, Mengji; Stindt, Jan; Ciesek, Sandra
    Sodium taurocholate cotransporting popypeptide variants modulate HDV entry according to their function as a bile acid transporter but do not influence the antiviral effect of Myrcludex-B
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 781
    Online Volltext: dx.doi.org/
  • Zhang, X.; Ge, J.; Huang, Z.; Sun, J.; Lu, Mengji; Hou, J.
    Expression and Function of Toll-Like Receptor 7 in Chronic Hepatitis B Patients Links to Antiviral Effect of PEG-IFN-A-2A Therapy
    In: Journal of Hepatology Jg. 64 (2016) Nr. 2, Suppl., S. S380 - S381
    Online Volltext: dx.doi.org/
  • Liu, J.; Yang, D.; Lu, Mengji
    HBV Strengthens Intrahepatic Myeloid-Derived Cells Mediated T Cell Tolerance through TLR1/2 Induced Kupffer Cell Expansion and IL-10 Production
    In: Journal of Hepatology Jg. 64 (2016) Nr. 2, Suppl., S. S515
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Zhang, Z.; Trippler, M.; Real, C.; Werner, M.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji
    Hepatitis B virus activates toll-like receptor 2 signaling upon infection of primary human hepatocytes
    In: Journal of Hepatology Jg. 64 (2016) Nr. 2, Suppl., S. S394
    Online Volltext: dx.doi.org/
  • Liu, J.; Xu, C.; Zheng, X.; Lu, Mengji; Yang, D.
    Increased TLR2 Expression in Peripheral CD4+T Cells Promotes TH17 Cells Responses and is Associated with Disease Aggravation of HBV-Related Acute-on-Chronic Liver Failure
    In: Journal of Hepatology Jg. 64 (2016) Nr. 2, Suppl., S. S307
    Online Volltext: dx.doi.org/
  • Zhang, X.; Liu, H.; Wang, B.; Ma, Z.; Zhang, J.; Yang, D.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Epigenetic control of Hepatitis B virus replication and farnesoid X receptor alpha expression by histone deacetylases 3
    In: Journal of Hepatology Jg. 56 (2012) Nr. Suppl. 2, S. S17
    Online Volltext: dx.doi.org/
  • Liu, H.; Zhang, J.; Zhang, X.; Bleekmann, B.; Kemper, T.; Roggendorf, Michael; Dittmer, Ulf; Lu, Mengji
    Genomic analysis of the host response to hepatitis b virus infection
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S187
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Hepatitis B virus surface antigen suppresses innate and adaptive immune responses of murine and human liver cells
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S174
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Wu, J.; Zhang, E.; Zhang, X.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    TLR-3 dependent immunological properties of liver cells are controlled by anti-inflammatory cytokines through modulation of MIR-155 expression
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S302 - S303
    Online Volltext: dx.doi.org/
  • Liu, J.; Jiang, M.; Ma, Z.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand stimulated mouse liver endothelial cells produce IL-12 and trigger CD8+ T-Cell immunity
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S311
    Online Volltext: dx.doi.org/
  • Ma, Z.; Zhang, E.; Zhang, X.; Liu, J.; Lin, Y.; Wu, J.; Kosinska, A.; Dittmer, Ulf; Roggendorf, Michael; Yang, D.; Lu, Mengji
    TLR2 ligand PAM3CSK4 inhibits peptide-induced deletion of CD8 T cells to viral antigens in mouse model
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S312
    Online Volltext: dx.doi.org/
  • Wu, J.; Chen, M.; Xia, Y.; Sun, C.; Lin, Y.; Wang, J.; Guo, Y.; Wang, B.; Song, J.; Lu, Mengji; Yang, D.
    The clearance of Hepatitis B virus (HBV) n hydrodynamik injection mouse model by polyinosinic-polycytidylic acid (POLYIC) treatment is dependent on interferon-gamma
    In: Journal of Hepatology Jg. 56 (2012) Nr. Supplement 2, S. S319
    Online Volltext: dx.doi.org/
  • Meng, Z.; Zhang, E.; Zhang, X.; Kosinska, A.; Xu, Y.; Yang, D.; Zhou, T.; Mason, W.; Roggendorf, Michael; Lu, Mengji
    DNA vaccination induces WHS/CAG specific T Cell immune responses in the newly constructed WHV transgenic mouse model
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S441
    Online Volltext: dx.doi.org/
  • Wang, J. Z.; Wang, B. J.; Huang, S. M.; Wu, J.; Zhu, Z. N.; Zhu, B.; Ding, H. H.; Feng, X. M.; Yin, Y.; Roggendorf, Michael; Lu, Mengji; Yang, D. L.
    Immunosuppression modulates the course of hepatitis B virus (HBV) infection in hydrodynamic injection mouse model
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S127
    Online Volltext: dx.doi.org/
  • Zhang, X.; Ma, Z.; Wu, C.; Zhang, E.; Bröring, Ruth; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of HBV replication by cell cycle and differentiation related micrornas
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S448 - S449
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Schumann, A.; Kosinska, A.; Lu, Mengji; Johrden, L.; Wildner, O.; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects woodchucks from hepatitis D virus infection
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S439
    Online Volltext: dx.doi.org/
  • Xu, L.; Beckebaum, Susanne; Wu, G.; Zhang, X.; Lu, Mengji; Iacob, S.; Paul, Andreas; Gerken, Guido; Cicinnati, Vito R.;
    The putative tumor suppressor microrna-101 negatively regulates the polycomb group protein enhancer of zeste homolog 2 (EZH2) in human hepatocellular carcinoma cells
    46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011,
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S110
    Online Volltext: dx.doi.org/
  • Jiang, M.; Wu, J.; Zhang, E.; Meng, Z.; Trippler, M.; Bröring, Ruth; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    446 HCV/TLR3- dependent innate and adaptive immune functions of non-parenchymal liver cells are controlled by interleukin-10 and transforming growth factor beta
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S180
    Online Volltext: dx.doi.org/
  • Zhang, E.; Kosinska, A.; Zhang, X.; Meng, Z.; Xu, Y.; Yang, D.; Roggendorf, Michael; Lu, Mengji;
    637 Enhanced TH2 type immune response in DNA immunization by fusion of WCTLA-4 to woodchuck hepatitis core antigen
    International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver,
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S249
    Online Volltext: dx.doi.org/
  • Roggendorf, Michael; Ke, X.Y.; Yang, Y.; Yang, D.L.; Zhang, X.Y.; Meng, Z.J.; Kemper, T.; Wang, Q.J.; Lu, Mengji; Lu, L.;
    OL-022 The effect of double-stranded DNA on replication of hepatitis B virus and cellular signalling
    Fourth Ditan International Conference on Infectious Diseases - Changing Face of Infectious Diseases. 15-18 July 2010, Beijing,
    In: International Journal of Infectious Diseases Jg. 14 (2010) Nr. Suppl. 2, S. S10
    Online Volltext: dx.doi.org/ (Open Access)
  • Lu, Mengji; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, Michael
    Protektion von Woodchucks gegen Woodchuckhepatitisvirus (WHV)-Infektion durch DNA-Immunisierung mit WHcAg- und WHsAg-exprimierenden Plasmiden
    In: Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998,: Abstracts / Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998 (1998) S. 30

    • Beiträge in Sammelwerken und Tagungsbänden

  • Liu, Jia; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Yang, Dongliang; Lu, Mengji
    Advanced Method for Isolation of Mouse Hepatocytes, Liver Sinusoidal Endothelial Cells, and Kupffer Cells
    In: Hepatitis B Virus: Methods and Protocols / Guo, Haitao; Cuconati, Andrea (Hrsg.) 2017, S. 249 - 258
    Online Volltext: dx.doi.org/
  • Bauer, Dirk; Wasmuth, Susanne; Lu, Mengji; Heiligenhaus, Arnd
    Particle-mediated administration of plasmid DNA on corneas of BALB/c mice
    In: Biolistic DNA Delivery: Methods and Protocols / Sudowe, Stephan; Reske-Kunz, Angelika B. (Hrsg.) 2013, S. 215 - 220
    Online Volltext: dx.doi.org/

    • Poster / Posterbeiträge

  • Liang, Yaojie; Luo, Xufeng; Schefczyk, Stefan; Baba, Hideo; Lu, Mengji; Bröring, Ruth;
    Expression of hepatitis B surface antigen in vivo and in vitro induces endoplasmic reticulum stress, impairs autophagy and promotes proliferation
    The International Liver Congress 2022 ; 22-26 June 2022, London, UK,
    In: Journal of Hepatology Jg. 77 (2022) Nr. Supplement 1: Abstracts of The International Liver CongressTM 2022, S. S643 - S644
    Online Volltext: dx.doi.org/ (Open Access)
  • Schefczyk, Stefan; Luo, Xufeng; Liang, Yaojie; Hasenberg, Mike; Walkenfort, Bernd; Trippler, Martin; Lu, Mengji; Wedemeyer, Heiner; Schmidt, Hartmut; Bröring, Ruth;
    Hepatitis B virus-replicating transgenic mice exhibit a functional but restricted responsiveness to exogenous Tlr3 and Rig-I stimuli
    The International Liver Congress 2022 ; 22-26 June 2022, London, UK,
    In: Journal of Hepatology Jg. 77 (2022) Nr. Supplement 1: Abstracts of The International Liver CongressTM 2022, S. S264 - S265
    Online Volltext: dx.doi.org/ (Open Access)
  • Luo, Xufeng; Zhang, Rui; Liang, Yaojie; Schefczyk, Stefan; Liu, Shi; Baba, Hideo; Lange, Christian; Wedemeyer, Heiner; Lu, Mengji; Bröring, Ruth;
    Hippo inactivation drives BMI1-associated proliferative hepatocarcinogenesis in chronic hepatitis B virus infection
    The International Liver Congress 2022 ; 22-26 June 2022, London, UK,
    In: Journal of Hepatology Jg. 77 (2022) Nr. Supplement 1: Abstracts of The International Liver CongressTM 2022, S. S642
    Online Volltext: dx.doi.org/ (Open Access)

    • Vorträge

  • Lu, Mengji; Hilken, Gero; Yang, D.; Roggendorf, Michael;
    Replikation von Deletionsmutanten des Woodchuck Hepatitis Virus (WHV) in primären Woodchuck Hepatitis Kulturen und in vivo nach einer Übertragung
    38. Tagung der GV-SOLAS, September 2000, Essen,
    (2000)