Personensuche

Personensuche

Bitte geben Sie den Namen der gesuchten Person ein.

Es wurde 1 Person gefunden.

Prof. Dr. rer. nat. Mengji Lu

Institut für Virologie der Medizinischen Fakultät

Anschrift
Virchowstr. 179 / Robert-Koch-Haus
45147 Essen
Telefon
+49 201 723 3530
E-Mail
mengji.lu@uni-due.de
Webseite
http://www.uni-due.de/virologie/res_lu_en.html

Funktionen

  • Universitätsprofessor/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Zhang, Yue; Yan, Hu; Li, Xian; Zhou, Dihan; Zhong, Maohua; Yang, Jingyi; Zhao, Bali; Fan, Xuxu; Fan, Jun; Shu, Jiayi; Lu, Mengji; Jin, Xia; Zhang, Ejuan; Yan, Huimin
    A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus
    In: PLoS neglected tropical diseases Jg. 16 (2022) Nr. 1,
    ISSN: 1935-2735; 1935-2727
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Xueyu; Wei, Zhiqiang; Lan, Tingyu; He, Yulin; Cheng, Bin; Li, Ruimin; Chen, Hongxia; Li, Fahong; Liu, Guohua; Jiang, Bin; Lin, Yong; Lu, Mengji; Meng, Zhongji
    CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation
    In: Autophagy Jg. 18 (2022) Nr. 2, S. 357 - 374
    ISSN: 1554-8635; 1554-8627
    Online Volltext: dx.doi.org/ (Open Access)
  • Zheng, Jiaxin; Deng, Yingying; Zhao, Zhenyu; Mao, Binli; Lu, Mengji; Lin, Yong; Huang, Ailong
    Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects
    In: Cellular & Molecular Immunology Jg. 19 (2022) Nr. 2, S. 150 - 157
    ISSN: 1672-7681; 1672-7681; 2042-0226
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Xueyu; Wei, Zhiqiang; Cheng, Bin; Li, Jia; He, Yulin; Lan, Tingyu; Kemper, Thekla; Lin, Yong; Jiang, Bin; Jiang, Yongfang; Meng, Zhongji; Lu, Mengji
    Endoplasmic reticulum stress promotes HBV production by enhancing use of the autophagosome/multivesicular body axis
    In: Hepatology Jg. 75 (2022) Nr. 2, S. 438 - 454
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/ (Open Access)
  • Xia, Jianbo; Cao, Liang; Zhao, Zhenyu; Deng, Yingying; Lu, Mengji; Wu, Chunchen; Lin, Yong
    HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy
    In: Genes & Diseases (2022) in press
    ISSN: 2352-3042
    Online Volltext: dx.doi.org/ (Open Access)
  • Xie, Xiaohong; Luo, Jinzhuo; Zhu, Dan; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Mengji; Zheng, Xin; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    HBeAg Is Indispensable for Inducing Liver Sinusoidal Endothelial Cell Activation by Hepatitis B Virus
    In: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022)
    ISSN: 2235-2988
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Fahong; Deng, Yingying; Zhang, Shenyan; Zhu, Beidi; Wang, Jun; Wang, Jinyu; Wang, Xueyu; Zhao, Zhenyu; Deng, Wanyu; Mao, Richeng; Shen, Zhongliang; Chen, Jieliang; Bröring, Ruth; Lin, Yong; Lu, Mengji; Zhang, Jiming
    Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 616 - 628
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Jia; Kemper, Thekla; Bröring, Ruth; Chen, Jieliang; Yuan, Zhenghong; Wang, Xueyu; Lu, Mengji
    Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication
    In: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022)
    ISSN: 2235-2988
    Online Volltext: dx.doi.org/ (Open Access)
  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Wang, Kai; Mennerich, Denise; Hu, Jie; Zhao, Zhenyu; Zheng, Jiaxin; Deng, Yingying; Katschinski, Benjamin; Xu, Shilei; Zhang, Guiji; Cai, Xuefei; Hu, Yuan; Wang, Jianwei; Lu, Mengji; Huang, Ailong; Tang, Ni; Trilling, Mirko; Lin, Yong
    Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
    In: Emerging Microbes & Infections Jg. 11 (2022) Nr. 1, S. 483 - 497
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Xueyu; Wei, Zhiqiang; Jiang, Yongfang; Meng, Zhongji; Lu, Mengji
    mTOR Signaling : The Interface Linking Cellular Metabolism and Hepatitis B Virus Replication
    In: Virologica Sinica Jg. 36 (2022) Nr. 6, S. 1303 - 1314
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Jia; Yang, Xuecheng; Wang, Hua; Li, Ziwei; Deng, Hui; Liu, Jing; Xiong, Shue; He, Junyi; Feng, Xuemei; Guo, Chunxia; Wang, Weixian; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Senff, Tina; Menne, Christopher; Timm, Jörg; Zhang, Yanfang; Deng, Fei; Lu, Yinping; Wu, Jun; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Wang, Baoju; Zheng, Xin
    Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairment
    In: mBio Jg. 12 (2021) Nr. 2, S. e00085 - 21
    ISSN: 2150-7511; 2161-2129
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Zhou, Xueshi; Lu, Hongzhou; Lu, Mengji; Huang, Lihua
    Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver Disease
    In: Frontiers in Medicine Jg. 8 (2021)
    ISSN: 2296-858X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Ziwei; Xiang, Tiandan; Liang, Boyun; Deng, Hui; Wang, Hua; Feng, Xuemei; Quan, Xufeng; Wang, Xiaoyan; Li, Sumeng; Lu, Sihong; Yang, Xuecheng; Wang, Baoju; Zelinskyy, Gennadiy; Trilling, Mirko; Sutter, Kathrin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Zheng, Xin; Liu, Jia
    Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World Setting
    In: Frontiers in Immunology Jg. 12 (2021)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Bröring, Ruth; Luo, Xufeng; Liu, Jia; Lu, Mengji
    Controversial: Early Innate Responses to Hepatitis B Virus Infection, an Explanation for Viral Persistence?
    In: Virologica Sinica Jg. 36 (2021) Nr. 1, S. 163 - 166
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ (Open Access)
  • Xiang, Tiandan; Liang, Boyun; Fang, Yaohui; Lu, Sihong; Li, Sumeng; Wang, Hua; Li, Huadong; Yang, Xiaoli; Shen, Shu; Zhu, Bin; Wang, Baoju; Wu, Jun; Liu, Jia; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Trilling, Mirko; Deng, Fei; Zheng, Xin
    Declining Levels of Neutralizing Antibodies Against SARS-CoV-2 in Convalescent COVID-19 Patients One Year Post Symptom Onset
    In: Frontiers in Immunology Jg. 12 (2021)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Du, Yanqin; Yang, Xiaoli; Li, Jia; Sokolova, Viktoriya; Zou, Shi; Han, Meihong; Yan, Hu; Wey, Karolin; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Epple, Matthias; Wu, Jun
    Delivery of toll-like receptor 3 ligand poly(I:C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect in a mouse model
    In: Acta Biomaterialia Jg. 133 (2021) S. 297 - 307
    ISSN: 1878-7568; 1742-7061
    Online Volltext: dx.doi.org/
  • Chen, Jieliang; Li, Yaming; Lai, Fritz; Wang, Yang; Sutter, Kathrin; Dittmer, Ulf; Ye, Jianyu; Zai, Wenjing; Liu, Min; Shen, Fang; Wu, Min; Hu, Kongying; Li, Baocun; Lu, Mengji; Zhang, Xiaonan; Zhang, Jiming; Li, Jianhua; Chen, Qingfeng; Yuan, Zhenghong
    Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ Signaling
    In: Hepatology Jg. 73 (2021) Nr. 2, S. 486 - 502
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/
  • Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Buitrago-Molina, Laura Elisa; Lu, Mengji; Meyer, Hemmo; Tong, Chun-Kit
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
    In: Autophagy Jg. 17 (2021) Nr. 1, S. 1 - 382
    ISSN: 1554-8635; 1554-8627
    Online Volltext: dx.doi.org/ (Open Access)
  • Xie, Xiaohong; Luo, Jinzhuo; Bröring, Ruth; Zhu, Dan; Zhou, Wenqing; Lu, Mengji; Zheng, Xin; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance
    In: Cellular & Molecular Immunology (2021)
    ISSN: 1672-7681; 2042-0226
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Islam, Heba; Kirschning, Carsten Jürgen; Lu, Hongzhou; Hoffmann, Daniel; Dittmer, Ulf; Lu, Mengji
    Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis
    In: Cell Death and Disease Jg. 12 (2021) Nr. 1, S. 34
    ISSN: 2041-4889
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhou, Li; He, Rui; Fang, Peining; Li, Mengqi; Yu, Haisheng; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Lin, Yong; Zhang, Rui; Trilling, Mirko; Bröring, Ruth; Lu, Mengji; Zhu, Ying; Liu, Shi
    Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 98
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Luo, Xufeng; Zhang, Rui; Lu, Mengji; Liu, Shi; Baba, Hideo Andrea; Gerken, Guido; Wedemeyer, Heiner; Bröring, Ruth
    Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 12 (2021)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Du, Yanqin; Bröring, Ruth; Li, Xiaoran; Zhang, Xiaoyong; Liu, Jia; Yang, Dongliang; Lu, Mengji
    In Vivo Mouse Models for Hepatitis B Virus Infection and Their Application
    In: Frontiers in Immunology Jg. 12 (2021)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xiong, Shue; Zhu, Dan; Liang, Boyun; Li, Mingyue; Pan, Wen; He, Junyi; Wang, Hua; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Liu, Di; Yang, Dongliang; Liu, Jia; Zheng, Xin
    Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss
    In: EBioMedicine Jg. 69 (2021)
    ISSN: 2352-3964
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Yanqin; Yan, Hu; Zou, Shi; Khera, Tanvi; Li, Jia; Han, Meihong; Yang, Xiaoli; Wang, Baoju; Liu, Jia; Sun, Shuilin; Zheng, Xin; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang; Wedemeyer, Heiner; Wu, Jun
    Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model
    In: Hepatology Communications (2021) in press
    ISSN: 2471-254X
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Jun; Liang, Bo-Yun; Fang, Yao-Hui; Wang, Hua; Yang, Xiao-Li; Shen, Shu; Chen, Liang-Kai; Li, Su-Meng; Lu, Si-Hong; Xiang, Tian-Dan; Liu, Jia; Le-Trilling, Vu Thuy Khanh; Lu, Mengji; Yang, Dong-Liang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral Immunity
    In: Frontiers in Immunology Jg. 12 (2021)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lin, Yong; Yuan, Jun; Long, Quanxin; Hu, Jieli; Deng, Haijun; Zhao, Zhenyu; Chen, Juan; Lu, Mengji; Huang, Ailong
    Patients with SARS-CoV-2 and HBV co-infection are at risk of greater liver injury
    In: Genes & Diseases Jg. 8 (2021) Nr. 4, S. 484 - 492
    ISSN: 2352-3042
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, Hongming; Rückborn, Meike; Le-Trilling, Vu Thuy Khanh; Zhu, Dan; Yang, Shangqing; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Yinping; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Trilling, Mirko; Liu, Jia
    Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in mice
    In: European Journal of Immunology Jg. 51 (2021) Nr. 2, S. 393 - 407
    ISSN: 1521-4141; 0014-2980
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Hongjun; Zhou, Jiao; Xiao, Peng; Lin, Yong; Gong, Xin; Liu, Shiyan; Xu, Qingjia; Wang, Minjin; Ren, Haiyan; Lu, Mengji; Wang, Yuan; Zhu, Jing; Xie, Zhiping; Li, Huihui; Lu, Kefeng
    PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes
    In: Autophagy Jg. 17 (2021) Nr. 8, S. 1907 - 1917
    ISSN: 1554-8635; 1554-8627
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Huang, Xuan; Zhang, Xiaoyong; Lu, Mengji
    Recent trends in the development of Toll-like receptor 7/8-targeting therapeutics
    In: Expert Opinion on Drug Discovery Jg. 16 (2021) Nr. 8, S. 869 - 880
    ISSN: 1746-045X; 1746-0441
    Online Volltext: dx.doi.org/
  • Wu, Jun; Liang, Boyun; Chen, Cunrong; Wang, Hua; Fang, Yaohui; Shen, Shu; Yang, Xiaoli; Wang, Baoju; Chen, Liangkai; Chen, Qi; Wu, Yang; Liu, Jia; Yang, Xuecheng; Li, Wei; Zhu, Bin; Zhou, Wenqing; Wang, Huan; Li, Sumeng; Lu, Sihong; Liu, Di; Li, Huadong; Krawczyk, Adalbert; Lu, Mengji; Yang, Dongliang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19
    In: Nature Communications Jg. 12 (2021) Nr. 1, S. 1813
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Zou, Shi; Du, Yanqin; Huang, Shunmei; Chen, Mingfa; Yang, Xiaoli; Li, Sumeng; Chen, Yingshan; Han, Meihong; Li, Jia; Yu, Qing; Littwitz-Salomon, Elisabeth; Huang, Hongming; Trilling, Mirko; Liu, Shi; Pei, Rongjuan; Liu, Jia; Wang, Baoju; Zheng, Xin; Lu, Mengji; Dittmer, Ulf; Sun, Shuilin; Yang, Dongliang; Wu, Jun
    Simultaneous or Prior Activation of Intrahepatic Type I Interferon Signaling Leads to Hepatitis B Virus Persistence in a Mouse Model
    In: Journal of Virology Jg. 95 (2021) Nr. 24,
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/
  • Du, Yanqin; Anastasiou, Olympia E.; Strunz, Benedikt; Scheuten, Janina; Bremer, Birgit; Kraft, Anke; Kleinsimglinhaus, Karolina; Todt, Daniel; Bröring, Ruth; Hardtke-Wolenski, Matthias; Wu, Jun; Yang, Dongliang; Dittmer, Ulf; Lu, Mengji; Cornberg, Markus; Björkström, Niklas K.; Khera, Tanvi; Wedemeyer, Heiner
    The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B virus infection
    In: Liver International Jg. 41 (2021) Nr. 9, S. 2046 - 2058
    ISSN: 1478-3231; 0106-9543; 1600-0676; 1478-3223
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhao, Zhenyu; Lu, Kefeng; Mao, Binli; Liu, Shi; Trilling, Mirko; Huang, Ailong; Lu, Mengji; Lin, Yong
    The interplay between emerging human coronavirus infections and autophagy
    In: Emerging Microbes & Infections Jg. 10 (2021) Nr. 1, S. 196 - 205
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Shichuan; Trilling, Mirko; Sutter, Kathrin; Dittmer, Ulf; Lu, Mengji; Zheng, Xin; Yang, Dongliang; Liu, Jia
    A Crowned Killer’s Résumé : Genome, Structure, Receptors, and Origin of SARS-CoV-2
    In: Virologica Sinica (2020)
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Xueyu; Lin, Yong; Kemper, Thekla; Chen, Jieliang; Yuan, Zhenghong; Liu, Shi; Zhu, Ying; Bröring, Ruth; Lu, Mengji
    AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy
    In: Cellular Microbiology Jg. 22 (2020) Nr. 2, S. e13131
    ISSN: 1462-5814; 1462-5822
    Online Volltext: dx.doi.org/ (Open Access)
  • Weng, Zhihong; Chen, Qiaosen; Li, Sumeng; Li, Huadong; Zhang, Qian; Lu, Sihong; Wu, Li; Xiong, Leiqun; Mi, Bobin; Liu, Di; Lu, Mengji; Yang, Dongliang; Jiang, Hongbo; Zheng, Shaoping; Zheng, Xin
    ANDC : An early warning score to predict mortality risk for patients with Coronavirus Disease 2019
    In: Journal of Translational Medicine Jg. 18 (2020) Nr. 1, S. 328
    ISSN: 1479-5876
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Wang, Jun; Lu, Mengji; Qiu, Yuanwang; Lu, Hongzhou
    Acute-on-Chronic Liver Failure From Chronic-Hepatitis-B, Who Is the Behind Scenes
    In: Frontiers in Microbiology Jg. 11 (2020) S. 583423
    ISSN: 1664-302X
    Online Volltext: dx.doi.org/ (Open Access)
  • Meng, Zhongji; Chen, Yuanyuan; Lu, Mengji
    Advances in Targeting the Innate and Adaptive Immune Systems to Cure Chronic Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 10 (2020) S. 3217
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Han, Mingfeng; Xu, Mengyuan; Zhang, Yafei; Liu, Zhongping; Li, Shasha; He, Tengfei; Li, Jinsong; Gao, Yong; Liu, Wanjun; Li, Tuantuan; Chen, Zixiang; Huang, Xin; Cheng, Guoling; Wang, Jun; Dittmer, Ulf; Witzke, Oliver; Zou, Guizhou; Li, Xiuyong; Lu, Mengji; Zhang, Zhenhua
    Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity
    In: Medical Microbiology and Immunology Jg. 209 (2020) S. 657 - 668
    ISSN: 1432-1831; 0300-8584
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Ling; Liu, Jia; Lu, Mengji; Yang, Dongliang; Zheng, Xin
    Author response to Letter to the Editor : Potential implications of COVID-19 in non-alcoholic fatty liver disease
    In: Liver International Jg. 40 (2020) Nr. 10, S. 2569 - 2570
    ISSN: 1478-3231; 0106-9543; 1600-0676; 1478-3223
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Yafei; Wang, Changtai; Han, Mingfeng; Ye, Jun; Gao, Yong; Liu, Zhongping; He, Tengfei; Li, Tuantuan; Xu, Mengyuan; Zhou, Luping; Zou, Guizhou; Lu, Mengji; Zhang, Zhenhua
    Correction to: Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference
    In: Virologica Sinica Jg. 35 (2020) Nr. 6, S. 885 - 886
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Chunli; Lu, Yinping; Zheng, Xin; Feng, Xuemei; Yang, Xuecheng; Timm, Jörg; Wu, Jun; Wang, Baoju; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Corrigendum: TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure (Frontiers in Immunology, (2017), 8, 10.3389/fimmu.2017.01609)
    In: Frontiers in Immunology Jg. 11 (2020) S. 1566
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Mengmeng; Xiong, Yan; Li, Mingyue; Zhang, Wenjing; Liu, Jia; Zhang, Yanfang; Xiong, Shue; Zou, Congcong; Liang, Boyun; Lu, Mengji; Yang, Dongliang; Peng, Cheng; Zheng, Xin
    Depletion but Activation of CD56dⁱmCD16⁺ NK Cells in Acute Infection with Severe Fever with Thrombocytopenia Syndrome Virus
    In: Virologica Sinica (2020)
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, Anding; Wang, Wenjie; Zhao, Xuecheng; Zhou, Xiaoxi; Yang, Dongliang; Lu, Mengji; Lv, Yongman
    Disappearance of antibodies to SARS-CoV-2 in a -COVID-19 patient after recovery
    In: Clinical Microbiology and Infection Jg. 26 (2020) Nr. 12, S. 1703 - 1705
    ISSN: 1469-0691; 1198-743X
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Yafei; Wang, Changtai; Han, Mingfeng; Ye, Jun; Gao, Yong; Liu, Zhongping; He, Tengfei; Li, Tuantuan; Xu, Mengyuan; Zhou, Luping; Zou, Guizhou; Lu, Mengji; Zhang, Zhenhua
    Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference
    In: Virologica Sinica Jg. 35 (2020) Nr. 6, S. 758 - 767
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Erratum for Westmeier et al., "Impaired Cytotoxic CD8⁺ T Cell Response in Elderly COVID-19 Patients"
    In: mBio Jg. 11 (2020) Nr. 5, S. 02243 - 02220
    ISSN: 2150-7511; 2161-2129
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Jun; Li, Qian; Yin, Yongmei; Zhang, Yingying; Cao, Yingying; Lin, Xiaoming; Huang, Lihua; Hoffmann, Daniel; Lu, Mengji; Qiu, Yuanwang
    Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19
    In: Frontiers in Immunology Jg. 11 (2020)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Rojas-Sánchez, Leonardo; Zhang, Ejuan; Sokolova, Viktoriya; Zhong, Maohua; Yan, Hu; Lu, Mengji; Li, Qian; Yan, Huimin; Epple, Matthias
    Genetic immunization against hepatitis B virus with calcium phosphate nanoparticles in vitro and in vivo
    In: Acta Biomaterialia Jg. 110 (2020) S. 254 - 265
    ISSN: 1878-7568; 1742-7061
    Online Volltext: dx.doi.org/
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Liu, Shi; Zhao, Kaitao; Kemper, Thekla; Yu, Haisheng; Li, Mengqi; Zhang, Jiming; Chen, Mingzhou; Zhu, Ying; Chen, Xinwen; Lu, Mengji
    Glucosamine promotes hepatitis B virus replication through its dual effects in suppressing autophagic degradation and inhibiting MTORC1 signaling
    In: Autophagy Jg. 16 (2020) Nr. 3, S. 548 - 561
    ISSN: 1554-8635; 1554-8627
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhang, Zhenhua; Trippler, Martin; Real, Catherine I.; Werner, Melanie; Luo, Xufeng; Schefczyk, Stefan; Kemper, Thekla; Anastasiou, Olympia E.; Ladiges, Yvonne; Treckmann, Jürgen-Walter; Paul, Andreas; Baba, Hideo Andreas; Allweiss, Lena; Dandri, Maura; Gerken, Guido; Wedemeyer, Heiner; Schlaak, Jörg Friedrich; Lu, Mengji; Bröring, Ruth
    Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes
    In: Hepatology: official journal of the American Association for the Study of Liver Diseases Jg. 72 (2020) Nr. 3, S. 829 - 844
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/ (Open Access)
  • Westmeier, Jaana; Paniskaki, Krystallenia; Karaköse, Zehra; Werner, Tanja; Sutter, Kathrin; Dolff, Sebastian; Overbeck, Marvin; Limmer, Andreas; Liu, Jia; Zheng, Xin; Brenner, Thorsten; Berger, Marc; Witzke, Oliver; Trilling, Mirko; Lu, Mengji; Yang, Dongliang; Babel, Nina; Westhoff, Timm; Dittmer, Ulf; Zelinskyy, Gennadiy
    Impaired cytotoxic CD8⁺ T cell response in elderly COVID-19 patients
    In: mBio Jg. 11 (2020) Nr. 5, S. e02243 - 20
    ISSN: 2150-7511; 2161-2129
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Yong; Zhao, Zhenyu; Huang, Ailong; Lu, Mengji
    Interplay between Cellular Autophagy and Hepatitis B Virus Replication : A Systematic Review
    In: Cells Jg. 9 (2020) Nr. 9, S. 2101
    ISSN: 2073-4409
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xu, Ling; Liu, Jia; Lu, Mengji; Yang, Dongliang; Zheng, Xin
    Liver injury during highly pathogenic human coronavirus infections
    In: Liver International: official journal of the International Association for the Study of the Liver Jg. 40 (2020) Nr. 5, S. 998 - 1004
    ISSN: 1478-3231; 1478-3223
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Jing; Li, Sumeng; Liu, Jia; Liang, Boyun; Wang, Xiaobei; Wang, Hua; Li, Wei; Tong, Qiaoxia; Yi, Jianhua; Zhao, Lei; Xiong, Lijuan; Guo, Chunxia; Tian, Jin; Luo, Jinzhuo; Yao, Jinghong; Pang, Ran; Shen, Hui; Peng, Cheng; Liu, Ting; Zhang, Qian; Wu, Jun; Xu, Ling; Lu, Sihong; Wang, Baoju; Weng, Zhihong; Han, Chunrong; Zhu, Huabing; Zhou, Ruxia; Zhou, Helong; Chen, Xiliu; Ye, Pian; Zhu, Bin; Wang, Lu; Zhou, Wenqing; He, Shengsong; He, Yongwen; Jie, Shenghua; Wei, Ping; Zhang, Jianao; Lu, Yinping; Wang, Weixian; Zhang, Li; Li, Ling; Zhou, Fengqin; Wang, Jun; Dittmer, Ulf; Lu, Mengji; Hu, Yu; Yang, Dongliang; Zheng, Xin
    Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients
    In: EBioMedicine Jg. 55 (2020)
    ISSN: 2352-3964
    Online Volltext: dx.doi.org/ (Open Access)
  • Yu, Haisheng; Li, Menqui; He, Rui; Fang, Peining; Wang, Qiming; Yi, Yu; Wang, Fubing; Zhou, Li; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Liu, Dan; Trilling, Mirko; Bröring, Ruth; Wiemer, Erik A.C.; Lu, Mengji; Zhu, Ying; Liu, Shi
    Major Vault Protein Promotes Hepatocellular Carcinoma Through Targeting Interferon Regulatory Factor 2 and Decreasing p53 Activity
    In: Hepatology Jg. 72 (2020) Nr. 2, S. 518 - 534
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/
  • Wang, Xueyu; Lin, Yong; Liu, Shi; Zhu, Ying; Lu, Kefeng; Bröring, Ruth; Lu, Mengji
    O-GlcNAcylation modulates HBV replication through regulating cellular autophagy at multiple levels
    In: FASEB Journal Jg. 34 (2020) Nr. 11, S. 14473 - 14489
    ISSN: 1530-6860; 0892-6638
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Jia; Zheng, Xin; Tong, Qiaoxia; Li, Wei; Wang, Baoju; Sutter, Kathrin; Trilling, Mirko; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang
    Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV
    In: Journal of Medical Virology Jg. 92 (2020) Nr. 5, S. 491 - 494
    ISSN: 1096-9071; 0146-6615
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Yan, Hu; Zhong, Maohua; Yang, Jingyi; Guo, Jiabao; Yu, Jie; Yang, Yi; Ma, Zhiyong; Zhao, Bali; Zhang, Yue; Wang, Junzhong; Wu, Chunchen; Dittmer, Ulf; Yang, Dongliang; Lu, Mengji; Zhang, Ejuan; Yan, Huimin
    TLR5 activation in hepatocytes alleviates the functional suppression of intrahepatic CD8⁺ T cells
    In: Immunology Jg. 161 (2020) Nr. 4, S. 325 - 344
    ISSN: 1365-2567; 0019-2805
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Ejuan; Yan, Hu; Li, Qian; Dittmer, Ulf; Yan, Huimin; Lu, Mengji
    Activation of the TLR signaling pathway in CD8+ T cells counteracts liver endothelial cell-induced T cell tolerance
    In: Cellular & Molecular Immunology Jg. 16 (2019) Nr. 9, S. 774 - 776
    ISSN: 2042-0226; 1672-7681
    Online Volltext: dx.doi.org/ (Open Access)
  • Yan, Yan; Chen, Renfang; Wang, Xu; Hu, Kai; Huang, Lihua; Lu, Mengji; Hu, Qinxue
    CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions in Viral Infection and Prevention
    In: Frontiers in Cell and Developmental Biology Jg. 7 (2019) S. 212
    ISSN: 2296-634X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wu, Chunchen; Li, Baolin; Zhang, Xiaoyong; Zhao, Kaitao; Chen, Yingshan; Yuan, Yifei; Liu, Yan; Chen, Rongjuan; Xu, Dongping; Chen, Xinwen; Lu, Mengji
    Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs
    In: Virologica Sinica Jg. 34 (2019) Nr. 4, S. 377 - 385
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, Shi; Liu, Li; Xu, Gang; Cao, Zhongying; Wang, Qing; Li, Shun; Peng, Nanfang; Yin, Jingchuan; Yu, Haisheng; Li, Mengqi; Xia, Zhangchuan; Zhou, Li; Lin, Yong; Wang, Xueyu; Li, Qian; Zhu, Chengliang; Yang, Xuecheng; Wang, Jun; She, Yinglong; Lu, Mengji; Zhu, Ying
    Epigenetic Modification Is Regulated by the Interaction of Influenza A Virus Nonstructural Protein 1 with the De Novo DNA Methyltransferase DNMT3B and Subsequent Transport to the Cytoplasm for K48-Linked Polyubiquitination
    In: Journal of Virology Jg. 93 (2019) Nr. 7,
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Kemper, Thekla; Squire, Anthony; Gunzer, Matthias; Zhang, Jiming; Chen, Xinwen; Lu, Mengji
    Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components
    In: Protein & Cell Jg. 10 (2019) Nr. 1, S. 60 - 66
    ISSN: 1674-8018; 1674-800X
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Yan; Zhou, Yi; Li, Xiaodong; Niu, Ming; Chen, Rongjuan; Shao, Jinman; Si, Lanlan; Luo, Dan; Lin, Yayun; Li, Le; Zhang, Kai; Xiao, Xiaohe; Xu, Zhihui; Liu, Min; Lu, Mengji; Zoulim, Fabien; Xu, Dongping
    Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice
    In: Emerging Microbes & Infections Jg. 8 (2019) Nr. 1, S. 354 - 365
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Jinyu; Li, Jing; Wu, Jingwen; Dong, Minhui; Shen, Zhongliang; Lin, Yong; Li, Fahong; Zhang, Yongmei; Mao, Richeng; Lu, Mengji; Zhang, Jiming
    Host Gene SEL1L Involved in Endoplasmic Reticulum-Associated Degradation Pathway Could Inhibit Hepatitis B Virus at RNA, DNA, and Protein Levels
    In: Frontiers in Microbiology Jg. 10 (2019)
    ISSN: 1664-302X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhang, Zhenhua; Wang, Changtai; Liu, Zhongping; Zou, Guizhou; Li, Jun; Lu, Mengji
    Host Genetic Determinants of Hepatitis B Virus Infection
    In: Frontiers in Genetics Jg. 10 (2019)
    ISSN: 1664-8021
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xu, Gang; Xia, Zhangchuan; Deng, Feiyan; Liu, Lin; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhu, Chengliang; Liu, Weiyong; Cheng, Zhikui; Zhu, Ying; Zhou, Li; Zhang, Yi; Lu, Mengji; Liu, Shi
    Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex
    In: PLoS Pathogens Jg. 15 (2019) Nr. 8, S. 1008002
    ISSN: 1553-7374; 1553-7366
    Online Volltext: dx.doi.org/ (Open Access)
  • Yang, Shangqing; Wang, Lu; Pan, Wen; Bayer, Wibke; Thoens, Christine; Heim, Kathrin; Dittmer, Ulf; Timm, Jörg; Wang, Qin; Yu, Qing; Luo, Jinzhuo; Liu, Yanan; Hofmann, Maike; Thimme, Robert; Zhang, Xiaoyong; Chen, Hongtao; Wang, Hua; Feng, Xuemei; Yang, Xuecheng; Lu, Yinping; Lu, Mengji; Yang, Dongliang; Liu, Jia
    MMP2/MMP9-mediated CD100 shedding is crucial for inducing intrahepatic anti-HBV CD8 T cell responses and HBV clearance
    In: Journal of Hepatology Jg. 71 (2019) Nr. 4, S. 685 - 698
    ISSN: 1600-0641; 0168-8278
    Online Volltext: dx.doi.org/
  • Liu, Yan; Wu, Chunchen; Chen, Rongjuan; Li, Xiaodong; Xu, Zhihui; Li, Qi; Li, Le; Wang, Fu-Sheng; Yang, Dongliang; Lu, Mengji; Xu, Dongping
    Molecular cloning and phenotypic analysis of drug‑resistance mutants with relevant S‑region variants of HBV for a patient during 189‑month anti‑HBV treatment
    In: Antiviral Therapy: an official publication of the International Society for Antiviral Research Jg. 24 (2019) Nr. 4, S. 237 - 246
    ISSN: 2040-2058; 1359-6535
    Online Volltext: dx.doi.org/
  • Wu, Jun; Han, Meihong; Li, Jia; Yang, Xiaoli; Zhen, Xin; Friedrich Schlaak, Joerg; Yang, Dongliang; Lu, Mengji
    Pattern recognition receptors and liver failure
    In: Critical Reviews in Immunology Jg. 39 (2019) Nr. 4, S. 289 - 311
    ISSN: 1040-8401; 2162-6472
    Online Volltext: dx.doi.org/
  • Yao, Yongxuan; Yang, Bo; Chen, Yingshan; Wang, Hui; Hu, Xue; Zhou, Yuan; Gao, Xiuzhu; Lu, Mengji; Niu, Junqi; Wen, Zhe; Wu, Chunchen; Chen, Xinwen
    RNA-binding motif protein 24 (RBM24) is involved in pregenomic RNA packaging by mediating interaction between hepatitis B virus polymerase and the epsilon element
    In: Journal of Virology Jg. 93 (2019) Nr. 6, S. e02161 - 18
    ISSN: 0022-538X; 1098-5514
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Liu, Shi; Kemper, Thekla; Li, Fahong; Squire, Anthony; Zhu, Ying; Zhang, Jiming; Chen, Xinwen; Lu, Mengji
    Synaptosomal-associated protein 29 is required for the autophagic degradation of hepatitis B virus
    In: The FASEB Journal Jg. 33 (2019) Nr. 5, S. 6023 - 6034
    ISSN: 0892-6638; 1530-6860
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Ejuan; Ma, Zhiyong; Li, Qian; Yan, Hu; Liu, Jia; Wu, Weimin; Guo, Jiabao; Zhang, Xiaoyong; Kirschning, Carsten Jürgen; Xu, Haifeng; Lang, Philipp A.; Yang, Dongliang; Dittmer, Ulf; Yan, Huimin; Lu, Mengji
    TLR2 stimulation increases cellular metabolism in CD8⁺ T cells and thereby enhances CD8⁺ T cell activation, function, and antiviral activity
    In: The Journal of Immunology Jg. 203 (2019) Nr. 11, S. 2872 - 2886
    ISSN: 1550-6606; 0022-1767; 1048-3233; 1047-7381
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Qian; Yan, Yan; Liu, Jia; Huang, Xuan; Zhang, Xiaoyong; Kirschning, Carsten Jürgen; Xu, Haifeng C.; Lang, Philipp A.; Dittmer, Ulf; Zhang, Ejuan; Lu, Mengji
    Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis
    In: Frontiers in Immunology Jg. 10 (2019) S. 2191
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ma, Zhiyong; Zhang, Ejuan; Gao, Shicheng; Xiong, Yong; Lu, Mengji
    Toward a functional cure for hepatitis B: The rationale and challenges for therapeutic targeting of the b cell immune response
    In: Frontiers in Immunology Jg. 10 (2019) S. 2308
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Yang, Li; Liu, Feifei; Tong, Xiankun; Hoffmann, Daniel; Zuo, Jianping; Lu, Mengji
    Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and Perspectives
    In: ACS Infectious Diseases Jg. 5 (2019) Nr. 5, S. 713 - 724
    ISSN: 2373-8227
    Online Volltext: dx.doi.org/
  • Schöneweis, Katrin; Motter, Neil; Roppert, Pia L.; Lu, Mengji; Wang, Baoju; Roehl, Ingo; Glebe, Dieter; Yang, Dongliang; Morrey, John D.; Roggendorf, Michael; Vaillant, Andrew
    Activity of nucleic acid polymers in rodent models of HBV infection
    In: Antiviral Research Jg. 149 (2018) S. 26 - 33
    ISSN: 1872-9096; 0166-3542
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Meng-Meng; Zhang, Wen-Jing; Weng, Xiu-Fang; Li, Ming-Yue; Liu, Jia; Xiong, Yan; Xiong, Shu-E; Zou, Cong-Cong; Wang, Hua; Lu, Mengji; Yang, Dong-Liang; Peng, Cheng; Zheng, Xin
    CD4 T cell loss and Th2 and Th17 bias are associated with the severity of severe fever with thrombocytopenia syndrome (SFTS)
    In: Clinical Immunology Jg. 195 (2018) S. 8 - 17
    ISSN: 1521-7035; 1521-6616
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhu, Bin; Zhu, Zhenni; Wang, Junzhong; Huang, Shunmei; Li, Fanghui; Wang, Lu; Liu, Yanan; Yan, Qi; Zhou, Shunchang; Lu, Mengji; Yang, Dongliang; Wang, Baoju
    Chinese woodchucks with different susceptibility to WHV infection differ in their genetic background exemplified by cytochrome B and MHC-DRB molecules
    In: Virology Journal Jg. 15 (2018) Nr. 1, S. 101
    ISSN: 1743-422X
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Meng-Meng; Zhang, Wen-Jing; Liu, Jia; Li, Ming-Yue; Zhang, Yan-Fang; Xiong, Yan; Xiong, Shu-E; Zou, Cong-Cong; Xiong, Lei-Qun; Liang, Bo-Yun; Lu, Mengji; Yang, Dong-Liang; Peng, Cheng; Zheng, Xin
    Dynamic changes in the immunological characteristics of T lymphocytes in surviving patients with severe fever with thrombocytopenia syndrome (SFTS)
    In: International Journal of Infectious Diseases Jg. 70 (2018) S. 72 - 80
    ISSN: 1878-3511; 1201-9712
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Qin; Pan, Wen; Liu, Yanan; Luo, Jinzhuo; Zhu, Dan; Lu, Yinping; Feng, Xuemei; Yang, Xuecheng; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment
    In: Frontiers in Immunology Jg. 9 (2018) S. 219
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Chun-Chen; Chen, Ying-Shan; Cao, Liang; Chen, Xin-Wen; Lu, Mengji
    Hepatitis B virus infection : Defective surface antigen expression and pathogenesis
    In: World Journal of Gastroenterology Jg. 24 (2018) Nr. 31, S. 3488 - 3499
    ISSN: 1007-9327
    Online Volltext: dx.doi.org/ (Open Access)
  • Shen, Fang; Li, Yaming; Wang, Yang; Sozzi, Vitina; Revill, Peter A.; Liu, Jiangxia; Gao, Lu; Yang, Guang; Lu, Mengji; Sutter, Kathrin; Dittmer, Ulf; Chen, Jieliang; Yuan, Zhenghong
    Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotype
    In: Hepatology Jg. 67 (2018) Nr. 4, S. 1237 - 1252
    ISSN: 1527-3350; 0270-9139
    Online Volltext: dx.doi.org/ (Open Access)
  • Ma, Zhiyong; Cao, Qian; Xiong, Yong; Zhang, Ejuan; Lu, Mengji
    Interaction between Hepatitis B Virus and Toll-Like Receptors : current status and potential therapeutic use for chronic hepatitis B
    In: Vaccines Jg. 6 (2018) Nr. 1, S. 6
    ISSN: 2076-393X
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, Shunmei; Wu, Jun; Gao, Xiaoyan; Zou, Shi; Chen, Liwen; Yang, Xilang; Sun, Chan; Du, Yanqin; Zhu, Bin; Li, Jia; Yang, Xuecheng; Feng, Xuemei; Wu, Chunchen; Shi, Chunwei; Wang, Baoju; Lu, Yinping; Liu, Jia; Zheng, Xin; Gong, Feili; Lu, Mengji; Yang, Dongliang
    LSECs express functional NOD1 receptors : A role for NOD1 in LSEC maturation-induced T cell immunity in vitro
    In: Molecular Immunology Jg. 101 (2018) S. 167 - 175
    ISSN: 1872-9142; 0161-5890
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, Shunmei; Zou, Shi; Chen, Mingfa; Gao, Xiaoyan; Chen, Liwen; Yang, Xilang; Yu, Qing; Zhao, Xiaoli; Du, Yanqin; Yang, Xuecheng; Lin, Yong; Wang, Baoju; Lu, Yinping; Liu, Jia; Zheng, Xin; Gong, Feili; Lu, Mengji; Yang, Dongliang; Wu, Jun
    Local stimulation of liver sinusoidal endothelial cells with a NOD1 agonist activates t cells and suppresses hepatitis b virus replication in mice
    In: Journal of Immunology Jg. 200 (2018) Nr. 9, S. 3170 - 3179
    ISSN: 1550-6606; 0022-1767
    Online Volltext: dx.doi.org/ (Open Access)
  • Peng, Nanfang; Yang, Xuecheng; Zhu, Chengliang; Zhou, Li; Yu, Haisheng; Li, Mengqi; Lin, Yong; Wang, Xueyu; Li, Qian; She, Yinglong; Wang, Jun; Zhao, Qian; Lu, Mengji; Zhu, Ying; Liu, Shi
    MicroRNA-302 cluster downregulates enterovirus 71–Induced innate immune response by targeting KPNA2
    In: Journal of Immunology Jg. 201 (2018) Nr. 1, S. 145 - 156
    ISSN: 1550-6606; 0022-1767
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Yong; Huang, Xuan; Wu, Jun; Liu, Jia; Chen, Mingfa; Ma, Zhiyong; Zhang, Ejuan; Liu, Yan; Huang, Shunmei; Li, Qian; Zhang, Xiaoyong; Hou, Jinlin; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Pre-activation of Toll-like receptor 2 enhances CD8⁺ T-cell responses and accelerates hepatitis B virus clearance in the mouse models
    In: Frontiers in Immunology Jg. 9 (2018) S. 1495
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Yao, Yongxuan; Yang, Bo; Cao, Huang; Zhao, Kaitao; Yuan, Yifei; Chen, Yingshan; Zhang, Zhenhua; Wang, Yun; Pei, Rongjuan; Chen, Jizheng; Hu, Xue; Zhou, Yuan; Lu, Mengji; Wu, Chunchen; Chen, Xinwen
    RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence article
    In: Emerging Microbes & Infections Jg. 7 (2018) S. 86
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ (Open Access)
  • Cao, Huang; Zhao, Kaitao; Yao, Yongxuan; Guo, Jing; Gao, Xiaoxiao; Yang, Qi; Guo, Min; Zhu, Wandi; Wang, Yun; Wu, Chunchen; Chen, Jizheng; Zhou, Yuan; Hu, Xue; Lu, Mengji; Chen, Xinwen; Pei, Rongjuan
    RNA binding protein 24 regulates the translation and replication of hepatitis C virus
    In: Protein and Cell Jg. 9 (2018) Nr. 11, S. 930 - 944
    ISSN: 1674-8018; 1674-800X
    Online Volltext: dx.doi.org/ (Open Access)
  • Du, Keye; Liu, Jia; Bröring, Ruth; Zhang, Xiaoyong; Yang, Dongliang; Dittmer, Ulf; Lu, Mengji
    Recent advances in the discovery and development of TLR ligands as novel therapeutics for chronic HBV and HIV infections
    In: Expert Opinion on Drug Discovery Jg. 13 (2018) Nr. 7, S. 661 - 670
    ISSN: 1746-045X; 1746-0441
    Online Volltext: dx.doi.org/
  • Yang, Jingyi; Zhao, Yue; Li, Peng; Yang, Yi; Zhang, Ejuan; Zhong, Maohua; Li, Yaoming; Zhou, DIhan; Cao, Yuan; Lu, Mengji; Shao, Feng; Yan, Huimin
    Sequence determinants of specific pattern-recognition of bacterial ligands by the NAIP-NLRC4 inflammasome
    In: Cell Discovery Jg. 4 (2018) Nr. 1, S. 18
    ISSN: 2056-5968
    Online Volltext: dx.doi.org/ (Open Access)
  • Yang, Li; Lu, Mengji
    Small molecule inhibitors of hepatitis B virus nucleocapsid assembly : a new approach to treat chronic HBV infection
    In: Current Medicinal Chemistry Jg. 25 (2018) Nr. 7, S. 802 - 813
    ISSN: 1875-533X; 0929-8673
    Online Volltext: dx.doi.org/
  • Liu, Jia; Yu, Qing; Wu, Weimin; Huang, Xuan; Bröring, Ruth; Werner, Melanie; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    TLR2 stimulation strengthens intrahepatic myeloid-derived cell-mediated T cell tolerance through inducing kupffer cell expansion and IL-10 production
    In: Journal of Immunology Jg. 200 (2018) Nr. 7, S. 2341 - 2351
    ISSN: 1550-6606; 0022-1767
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhao, Kaitao; Liu, Shuhui; Chen, Yingshan; Yao, Yongxuan; Zhou, Ming; Yuan, Yifei; Wang, Yun; Pei, Rongjuan; Chen, Jizheng; Hu, Xue; Zhou, Yuan; Zhao, He; Lu, Mengji; Wu, Chunchen; Chen, Xinwen
    Upregulation of HBV transcription by sodium taurocholate cotransporting polypeptide at the postentry step is inhibited by the entry inhibitor Myrcludex B
    In: Emerging Microbes & Infections Jg. 7 (2018) S. 186
    ISSN: 2222-1751
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhao, Kaitao; Wu, Chunchen; Yao, Yongxuan; Cao, Liang; Zhang, Zhenhua; Yuan, Yifei; Wang, Yun; Pei, Rongjuan; Chen, Jizheng; Hu, Xue; Zhou, Yuan; Lu, Mengji; Chen, Xinwen
    Ceruloplasmin inhibits the production of extracellular hepatitis B virions by targeting its middle surface protein
    In: Journal of General Virology Jg. 98 (2017) Nr. 6, S. 1410 - 1421
    ISSN: 1465-2099; 0022-1317
    Online Volltext: dx.doi.org/
  • Zhang, Wenjing; Li, Mengmeng; Xiong, Shue; Wang, Hua; Xiong, Yan; Li, Mingyue; Lu, Mengji; Yang, Dongliang; Peng, Cheng; Zheng, Xin
    Decreased myeloid dendritic cells indicate a poor prognosis in patients with severe fever with thrombocytopenia syndrome
    In: International Journal of Infectious Diseases Jg. 54 (2017) S. 113 - 120
    ISSN: 1878-3511; 1201-9712
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Zhou, Yun; Li, Sheng; Tang, Zongsheng; Xu, Chunli; Huang, Shunmei; Wu, Jun; Dittmer, Ulf; Dickow, Julia; Sutter, Kathrin; Lu, Mengji; Yang, Dongliang; Song, Jingjiao
    Different antiviral effects of IFNα and IFNβ in an HBV mouse model
    In: Immunobiology Jg. 222 (2017) Nr. 3, S. 562 - 570
    ISSN: 0171-2985; 1878-3279
    Online Volltext: dx.doi.org/
  • Song, Jingjiao; Li, Sheng; Zhou, Yun; Liu, Jia; Francois, Sandra; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Sutter, Kathrin
    Different antiviral effects of IFNα subtypes in a mouse model of HBV infection
    In: Scientific Reports Jg. 7 (2017) Nr. 1, S. 334
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Liu, Chao; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Ge, Jun; Li, Yongyin; Liao, Baolin; Sun, Jian; Peng, Jie; Lu, Mengji; Hou, Jinlin; Zhang, Xiaoyong
    Elevated expression of chemokine CXCL13 in chronic hepatitis B patients links to immune control during antiviral therapy
    In: Frontiers in Immunology Jg. 8 (2017) S. 323
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, C.; Bröring, Ruth; Hideo, B.A.; Real, C.I.; Zhang, R.; Lu, Mengji; Gerken, Guido
    Hepatic expression of oncogenes Bmi1 and Dkk1 can be induced by treatment with hepatitis B virus particles or Lipopolysaccharide in vitro and is up-regulated in liver biopsies of patients with chronic HBV infection
    In: Journal of Hepatology Jg. 66 (2017) Nr. 1, S. S700
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, Ruiyong; Real, Catherine I.; Liu, Chao; Baba, Hideo Andreas; Gerken, Guido; Lu, Mengji; Bröring, Ruth
    Hepatic expression of oncogenes Bmi1 and Dkk1 is up-regulated in hepatitis B virus surface antigen–transgenic mice and can be induced by treatment with HBV particles or lipopolysaccharides in vitro
    In: International Journal of Cancer Jg. 141 (2017) Nr. 2, S. 354 - 363
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Wan, Yushun; Cao, Wei; Han, Tao; Ren, Sheng; Feng, Jian; Chen, TieLong; Wang, Jun; Bröring, Ruth; Lu, Mengji; Zhu, Ying
    Inducible Rubicon facilitates viral replication by antagonizing interferon production
    In: Cellular & Molecular Immunology Jg. 14 (2017) Nr. 7, S. 607 - 620
    ISSN: 1672-7681; 2042-0226
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Fang, Zhong; Roggendorf, Michael; Wang, Cong; Lin, Yong; Liu, Jia; Lu, Mengji; Dietze, Kirsten; Chen, Jieliang; Dittmer, Ulf; Yeh, Shiou-Hwei; Wu, Weimin; Kemper, Thekla; Kosinska, Anna D.; Lenart, Marzena; Yuan, Zhenghong; Pishraft-Sabet, Leila
    Low hepatitis B virus-specific T-cell response in males correlates with high regulatory T-cell numbers in murine models
    In: Hepatology Jg. 66 (2017) Nr. 1, S. 69 - 83
    ISSN: 1527-3350
    Online Volltext: dx.doi.org/
  • Liu, Shuhui; Zhao, Kaitao; Su, Xi; Lu, Lu; Zhao, He; Zhang, Xianwen; Wang, Yun; Wu, Chunchen; Chen, Jizheng; Zhou, Yuan; Hu, Xue; Wang, Yanyi; Lu, Mengji; Chen, Xinwen; Pei, Rongjuan
    MITA/STING and its alternative splicing isoform MRP restrict hepatitis B virus replication
    In: PLoS ONE Jg. 12 (2017) Nr. 1, S. e0169701
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Deng, Wanyu; Zhang, Xiaoyong; Ma, Zhiyong; Lin, Yong; Lu, Mengji
    MicroRNA-125b-5p mediates post-transcriptional regulation of hepatitis B virus replication via the LIN28B/let-7 axis
    In: RNA biology Jg. 14 (2017) Nr. 10, S. 1389 - 1398
    ISSN: 1555-8584; 1547-6286
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Chen, Xueyuan; Zhou, Li; Peng, Nanfang; Yu, Haisheng; Li, Mengqi; Cao, Zhongying; Lin, Yong; Wang, Xueyu; Li, Qian; Wang, Jun; She, Yinglong; Zhu, Chengliang; Lu, Mengji; Zhu, Ying; Liu, Shi
    MicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction
    In: The Journal of Biological Chemistry (JBC) Jg. 292 (2017) Nr. 52, S. 21291 - 21303
    ISSN: 0021-9258; 1083-351X
    Online Volltext: dx.doi.org/
  • Pett, Christian; Cai, Hui; Liu, Jia; Palitzsch, Björn; Schorlemer, Manuel; Hartmann, Sebastian; Stergiou, Natascha; Lu, Mengji; Kunz, Horst; Schmitt, Edgar; Westerlind, Ulrika
    Microarray analysis of antibodies induced with synthetic antitumor vaccines : specificity against diverse mucin core structures
    In: Chemistry - A European Journal Jg. 23 (2017) Nr. 16, S. 3875 - 3884
    ISSN: 0947-6539; 1521-3765
    Online Volltext: dx.doi.org/
  • Liu, Yanan; Wang, Junzhong; Wang, Lu; Wang, Baoju; Yang, Shangqing; Wang, Qin; Luo, Jinzhuo; Feng, Xuemei; Yang, Xuecheng; Lu, Yinping; Roggendorf, Michael; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Molecular cloning, characterization and expression analysis of Tim-3 and Galectin-9 in the woodchuck model
    In: Molecular Immunology Jg. 83 (2017) S. 127 - 136
    ISSN: 1872-9142; 0161-5890
    Online Volltext: dx.doi.org/
  • Wu, Weimin; Liu, Yan; Lin, Yong; Pan, Danzhen; Yang, Dongliang; Lu, Mengji; Xu, Yang
    PreC and C Regions of Woodchuck Hepatitis Virus Facilitate Persistent Expression of Surface Antigen of Chimeric WHV-HBV Virus in the Hydrodynamic Injection BALB/c Mouse Model
    In: Viruses Jg. 9 (2017) Nr. 2, S. 35
    ISSN: 1999-4915
    Online Volltext: dx.doi.org/ (Open Access)
  • Meng, Zhongji; Lu, Mengji
    RNA Interference-Induced Innate Immunity, Off-Target Effect, or Immune Adjuvant?
    In: Frontiers in Immunology Jg. 8 (2017) S. 331
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Su, Xi; Liu, Shuhui; Zhang, Xianwen; Lam, Sin Man; Hu, Xue; Zhou, Yuan; Chen, Jizheng; Wang, Yun; Wu, Chunchen; Shui, Guanghou; Lu, Mengji; Pei, Rongjuan; Chen, Xinwen
    Requirement of cytosolic phospholipase A2 gamma in lipid droplet formation
    In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Jg. 1862 (2017) Nr. 7, S. 692 - 705
    ISSN: 1879-2618; 1388-1981
    Online Volltext: dx.doi.org/
  • Xu, Chunli; Lu, Yinping; Zheng, Xin; Feng, Xuemei; Yang, Xuecheng; Timm, Jörg; Wu, Jun; Wang, Baoju; Lu, Mengji; Yang, Dongliang; Liu, Jia
    TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure
    In: Frontiers in Immunology Jg. 8 (2017) S. 1609
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Ma, Zhiyong; Liu, Jia; Wu, Weimin; Zhang, Ejuan; Zhang, Xiaoyong; Li, Qian; Zelinskyy, Gennadiy; Buer, Jan; Dittmer, Ulf; Kirschning, Carsten Jürgen; Lu, Mengji
    The IL-1R/TLR signaling pathway is essential for efficient CD8+ T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model
    In: Cellular & Molecular Immunology Jg. 14 (2017) Nr. 12, S. 997 - 1008
    ISSN: 1672-7681; 2042-0226
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Lei; Li, Sheng; Zhou, Yun; Yang, Lu; Zhou, Di; Yang, Yan; Lu, Mengji; Yang, Dongliang; Song, Jingjiao
    The dose of HBV genome contained plasmid has a great impact on HBV persistence in hydrodynamic injection mouse model
    In: Virology Journal Jg. 14 (2017) S. 205
    ISSN: 1743-422X
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Yong; Deng, Wanyu; Pang, Jinke; Kemper, Thekla; Hu, Jing; Yin, Jian; Zhang, Jiming; Lu, Mengji
    The microRNA-99 family modulates hepatitis B virus replication by promoting IGF-1R/PI3K/Akt/mTOR/ULK1 signaling-induced autophagy
    In: Cellular Microbiology Jg. 19 (2017) Nr. 5, S. e12709
    ISSN: 1462-5822; 1462-5814
    Online Volltext: dx.doi.org/
  • Pang, Jinke; Zhang, Geng; Lin, Yong; Xie, Zhanglian; Liu, Hongyan; Tang, Libo; Lu, Mengji; Yan, Ran; Guo, Haitao; Sun, Jian; Hou, Jinlin; Zhang, Xiaoyong
    Transforming growth factor β-activated kinase 1 transcriptionally suppresses hepatitis B virus replication
    In: Scientific Reports Jg. 7 (2017) S. 39901
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Dietze, Kirsten; Schimmer, Simone; Kretzmer, Freya; Wang, Junzhong; Lin, Yong; Huang, Xuan; Wu, Weimin; Wang, Baoju; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Liu, Jia
    Characterization of the Treg Response in the Hepatitis B Virus Hydrodynamic Injection Mouse Model
    In: PLoS ONE Jg. 11 (2016) Nr. 3, S. e0151717
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Meng, Zhongji; Zhang, Xiaoyong; Pei, Rongjuan; Zhang, Ejuan; Kemper, Thekla; Vollmer, Jörg; Davis, Heather L.; Glebe, Dieter; Gerlich, Wolfram; Roggendorf, Michael; Lu, Mengji
    Combination therapy including CpG oligodeoxynucleotides and entecavir induces early viral response and enhanced inhibition of viral replication in a woodchuck model of chronic hepadnaviral infection
    In: Antiviral Research Jg. 125 (2016) S. 14 - 24
    ISSN: 1872-9096; 0166-3542
    Online Volltext: dx.doi.org/
  • Zhang, Xiaoyong; Liu, Hongyan; Xie, Zhanglian; Deng, Wangyu; Wu, Chunchen; Qin, Bo; Hou, Jinlin; Lu, Mengji
    Epigenetically regulated miR-449a enhances hepatitis B virus replication by targeting cAMP-responsive element binding protein 5 and modulating hepatocytes phenotype
    In: Scientific Reports Jg. 6 (2016) S. 25389
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Zhen-Hua; Wu, Chun-Chen; Chen, Xin-Wen; Li, Xu; Li, Jun; Lu, Mengji
    Genetic variation of hepatitis B virus and its significance for pathogenesis
    In: World Journal of Gastroenterology Jg. 22 (2016) Nr. 1, S. 126 - 144
    ISSN: 1007-9327
    Online Volltext: dx.doi.org/ (Open Access)
  • Real, Catherine Isabell; Bröring, Ruth; Schlaak, Jörg Friedrich; Gerken, Guido; Schirmbeck, Reinhold; Vornlocher, Hans-Peter; Dittmer, Ulf; Gibbert, Kathrin; John, Matthias Johannes; Ickenstein, Ludger Markus; Jahn-Hofmann, Kerstin; Deckert, Jochen; Hossbach, Markus; Trippler, Martin; Huang, Xuan; Lu, Mengji; Liu, Jia
    Hepatitis B virus genome replication triggers toll-like receptor 3-dependent interferon responses in the absence of hepatitis B surface antigen
    In: Scientific Reports Jg. 6 (2016) S. 24865
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Peng, Cheng; Wang, Hua; Zhang, Wen-Jing; Jie, Sheng-Hua; Tong, Qiao-Xia; Lu, Mengji; Yang, Dong-Liang
    Inhibitory effect of miR-125b on hepatitis C virus core protein-induced TLR2/MyD88 signaling in THP-1 cells
    In: World Journal of Gastroenterology Jg. 22 (2016) Nr. 17, S. 4354 - 4361
    ISSN: 2219-2840; 1007-9327
    Online Volltext: dx.doi.org/ (Open Access)
  • Yan, Qi; Li, Mengmeng; Liu, Qin; Li, Fanghui; Zhu, Bin; Wang, Junzhong; Lu, Yinping; Liu, Jia; Wu, Jun; Zheng, Xin; Lu, Mengji; Wang, Baoju; Yang, Dongliang
    Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV)
    In: Scientific Reports Jg. 6 (2016) S. 28776
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Lu; Wang, Junzhong; Liu, Yana; Wang, Baoju; Yang, Shangqing; Yu, Qing; Roggendorf, Michael; Lu, Mengji; Liu, Jia; Yang, Dongliang
    Molecular cloning, characterization and expression analysis of TGF-? and receptor genes in the woodchuck model
    In: Gene Jg. 595 (2016) Nr. 1, S. 1 - 8
    ISSN: 0378-1119
    Online Volltext: dx.doi.org/
  • Yan, Qi; Liu, Qin; Li, Meng-Meng; Li, Fang-Hui; Zhu, Bin; Wang, Jun-Zhong; Lu, Yin-Ping; Liu, Jia; Wu, Jun; Zheng, Xin; Lu, Mengji; Wang, Bao-Ju; Yang, Dong-Liang
    Molecular cloning, characterization and expression analysis of woodchuck retinoic acid-inducible gene I
    In: Journal of Huazhong University of Science and Technology Jg. 36 (2016) Nr. 3, S. 335 - 343
    ISSN: 1672-0733
    Online Volltext: dx.doi.org/
  • Liu, Wei; Lu, Mengji; Liu, Yutian; Zhang, Wenjing; Chen, Qian; Song, Hongxuan
    Multidrug resistance protein 4 is a critical protein associated with the antiviral efficacy of nucleos(t)ide analogues
    In: Liver International Jg. 36 (2016) Nr. 9, S. 1284 - 1294
    ISSN: 1478-3231; 1600-0676; 0106-9543
    Online Volltext: dx.doi.org/
  • Li, Fahong; Lu, Mengji; Li, Ji; Zhang, Yijun; Wang, Jinyu; Deng, Wangyu; Zhou, Pu
    Serum microRNA-125b correlates with hepatitis B viral replication and liver necroinflammation
    In: Clinical Microbiology and Infection Jg. 22 (2016) Nr. 4, S. 384.e1 - 384.e10
    ISSN: 1469-0691; 1198-743X
    Online Volltext: dx.doi.org/ (Open Access)
  • Deng, Wanyu; Lu, Mengji
    The role of microRNAs in hepatocyte metabolism and hepatitis B virus replication
    In: Virologica Sinica Jg. 31 (2016) Nr. 6, S. 472 - 479
    ISSN: 1674-0769; 1995-820X
    Online Volltext: dx.doi.org/
  • Liu, Yanan; Wang, Baoju; Wang, Lu; Vikash, Vikash; Wang, Qin; Roggendorf, Michael; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Transcriptome Analysis and Comparison of Marmota monax and Marmota himalayana
    In: PLoS ONE Jg. 11 (2016) Nr. 11, S. e0165875
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Ye, Zhou; Zhang, Quan; Wang, Shengtao; Bharate, Priya; Varela-Aramburu, Silvia; Lu, Mengji; Seeberger, Peter H; Yin, Jian
    Tumour-Targeted Drug Delivery with Mannose-Functionalized Nanoparticles Self-Assembled from Amphiphilic β-Cyclodextrins
    In: Chemistry: A European Journal Jg. 22 (2016) Nr. 43, S. 15216 - 15221
    ISSN: 0947-6539; 1521-3765
    Online Volltext: dx.doi.org/
  • Huang, Zuxiong; Ge, Jun; Pang, Jinke; Liu, Hongyan; Chen, Jinjun; Liao, Baolin; Huang, Xuan; Zuo, Daming; Sun, Jian; Lu, Mengji; Zhang, Xiaoyong; Hou, Jinlin
    Aberrant expression and dysfunction of TLR2 and its soluble form in chronic HBV infection and its regulation by antiviral therapy
    In: Antiviral Research Jg. 118 (2015) S. 10 - 19
    ISSN: 1872-9096
    Online Volltext: dx.doi.org/
  • Peng, Cheng; Lu, Mengji; Yang, Dongliang
    CRISPR/Cas9-based tools for targeted genome editing and replication control of HBV
    In: Virologica Sinica Jg. 30 (2015) Nr. 5, S. 317 - 325
    ISSN: 1674-0769; 1995-820X
    Online Volltext: dx.doi.org/
  • Hu, Jing; Qiu, Liying; Wang, Xiaoli; Zou, Xiaopeng; Lu, Mengji; Yin, Jian
    Carbohydrate-based vaccine adjuvants : discovery and development
    In: Expert Opinion on Drug Discovery Jg. 10 (2015) Nr. 10, S. 1133 - 1144
    ISSN: 1746-045X; 1746-0441
    Online Volltext: dx.doi.org/
  • Ma, Zhiyong; Zhang, Ejuan; Yang, Dongliang; Lu, Mengji
    Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses
    In: Cellular & Molecular Immunology Jg. 12 (2015) Nr. 3, S. 273 - 282
    ISSN: 1672-7681
    Online Volltext: dx.doi.org/
  • Zhang, Ejuan; Kosinska, Anna; Lu, Mengji; Yan, Huimin; Roggendorf, Michael
    Current status of immunomodulatory therapy in chronic hepatitis B, fifty years after discovery of the virus : Search for the "magic bullet" to kill cccDNA
    In: Antiviral Research Jg. 123 (2015) S. 193 - 203
    ISSN: 0166-3542
    Online Volltext: dx.doi.org/
  • Li, Songxia; Zhao, Kaitao; Liu, Shuhui; Wu, Chunchen; Yao, Yongxuan; Cao, Liang; Hu, Xue; Zhou, Yuan; Wang, Yun; Pei, Rongjuan; Lu, Mengji; Chen, Xinwen
    HBsAg sT123N mutation induces stronger antibody responses to HBsAg and HBcAg and accelerates in vivo HBsAg clearance
    In: Virus research Jg. 210 (2015) Nr. December, S. 119 - 125
    ISSN: 0168-1702
    Online Volltext: dx.doi.org/
  • Zhang, Zhenhua; Xia, Jianbo; Sun, Binghu; Dai, Yu; Li, Xu; Schlaak, Jörg Friedrich; Lu, Mengji
    In vitro and in vivo replication of a chemically synthesized consensus genome of hepatitis B virus genotype B
    In: Journal of Virological Methods Jg. 213 (2015) S. 57 - 64
    ISSN: 0166-0934
    Online Volltext: dx.doi.org/
  • Lin, Y.; Lu, Mengji; Pang, J.; Kemper, T.; Deng, W.
    Microrna-99 family modulates hepatitis B virus replication by targeting the phosphoinositide 3-KINASE/Akt/mTOR signaling pathway
    In: Journal of Hepatology Jg. 62 (2015) Nr. Suppl. 2, S. S526
    ISSN: 1600-0641
    Online Volltext: dx.doi.org/
  • Wang, Chang-Tai; Zhang, Ya-Fei; Sun, Bing-Hu; Dai, Yu; Zhu, Hui-Lan; Xu, Yuan-Hong; Lu, Mengji; Yang, Dong-Liang; Li, Xu; Zhang, Zhen-Hua
    Models for predicting hepatitis B e antigen seroconversion in response to interferon-α in chronic hepatitis B patients
    In: World Journal of Gastroenterology Jg. 21 (2015) Nr. 18, S. 5668 - 5676
    ISSN: 1007-9327
    Online Volltext: dx.doi.org/ (Open Access)
  • Sun, C.; Huang, S.; Wu, J.; Lu, Mengji; Zhao, X.; Lin, Y.; Zheng, X.; Chen, M.; Xia, Y.; Wang, B.; Yang, D.
    NOD1 ligand modulates the course of hepatitis B virus infection in hydrodynamic injection mouse model
    In: Journal of Clinical Virology Jg. 69 (2015) S. 236
    ISSN: 1386-6532
    Online Volltext: dx.doi.org/
  • Pan, Danzhen; Lin, Yong; Wu, Weimin; Song, Jingjiao; Zhang, Ejuan; Wu, Chunchen; Chen, Xinwen; Hu, Kanghong; Yang, Dongliang; Xu, Yang; Lu, Mengji
    Persistence of the recombinant genomes of woodchuck hepatitis virus in the mouse model
    In: PLoS ONE Jg. 10 (2015) Nr. 5, S. e0125658
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Guo, Min; Pei, Rongjuan; Yang, Qi; Cao, Huang; Wang, Yun; Wu, Chunchen; Chen, Jizheng; Zhou, Yuan; Hu, Xue; Lu, Mengji; Chen, Xinwen
    Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation
    In: Journal of Virology Jg. 89 (2015) Nr. 4, S. 2367 - 2377
    ISSN: 0022-538X; 1098-5514
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Jin-Yu; Mao, Ri-Cheng; Zhang, Yong-Mei; Zhang, Yi-Jun; Liu, Hong-Yan; Qin, Yan-Li; Lu, Mengji; Zhang, Ji-Ming
    Serum microRNA-124 is a novel biomarker for liver necroinflammation in patients with chronic hepatitis B virus infection
    In: Journal of viral hepatitis Jg. 22 (2015) Nr. 2, S. 126 - 134
    ISSN: 1365-2893; 1352-0504
    Online Volltext: dx.doi.org/
  • Han, Tao; Wan, Yushun; Wang, Jun; Zhao, Peng; Yuan, Yue; Wang, Li; She, Yinglong; Bröring, Ruth; Lu, Mengji; Ye, Linbai; Zhu, Ying
    Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway
    In: Journal of Immunology Jg. 194 (2015) Nr. 6, S. 2757 - 2768
    ISSN: 0022-1767; 1048-3233; 1047-7381
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Weimin; Dietze, Kirsten; Gibbert, Kathrin; Lang, Karl S.; Trilling, Mirko; Yan, Huimin; Wu, Jun; Yang, Dongliang; Lu, Mengji; Roggendorf, Michael; Dittmer, Ulf; Liu, Jia
    TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infection
    In: Scientific Reports Jg. 5 (2015) S. 10501
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Roggendorf, Michael; Kosinska, Anna D; Liu, Jia; Lu, Mengji
    The Woodchuck, a Nonprimate Model for Immunopathogenesis and Therapeutic Immunomodulation in Chronic Hepatitis B Virus Infection
    In: Cold Spring Harbor Perspectives in Medicine Jg. 5 (2015) Nr. 12, S. a021451
    ISSN: 2157-1422
    Online Volltext: dx.doi.org/
  • Kosinska, Anna D.; Liu, Jia; Lu, Mengji; Roggendorf, Michael
    Therapeutic vaccination and immunomodulation in the treatment of chronic hepatitis B : preclinical studies in the woodchuck
    In: Medical microbiology and immunology (2015) Nr. 204,1, S. 103 - 114
    ISSN: 0300-8584; 1432-1831
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Ejuan; Lu, Mengji
    Toll-like receptor (TLR)-mediated innate immune responses in the control of hepatitis B virus (HBV) infection
    In: Medical Microbiology and Immunology Jg. 204 (2015) Nr. 1, S. 11 - 20
    ISSN: 0300-8584; 1432-1831
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Ejuan; Kosinska, Anna D; Ma, Zhiyong; Dietze, Kirsten; Xu, Yang; Meng, Zhongji; Zhang, Xiaoyong; Wang, Junzhong; Wang, Baoju; Dittmer, Ulf; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    Woodchuck hepatitis virus core antigen-based DNA and protein vaccines induce qualitatively different immune responses that affect T cell recall responses and antiviral effects
    In: Virology Jg. 475 (2015) S. 56 - 65
    ISSN: 0042-6822
    Online Volltext: dx.doi.org/ (Open Access)
  • Chen, H.; Pei, R.; Zhu, W.; Zeng, R.; Wang, Y.; Lu, Mengji; Chen, X.
    An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type i IFNs
    In: Journal of Immunology Jg. 192 (2014) Nr. 3, S. 1162 - 1170
    ISSN: 0022-1767; 0022-1767
    Online Volltext: dx.doi.org/ (Open Access)
  • Cao, L.; Wu, C.; Shi, H.; Gong, Z.; Zhang, E.; Wang, H.; Zhao, K.; Liu, S.; Li, S.; Gao, X.; Wang, Y.; Pei, R.; Lu, Mengji; Chen, X.
    Coexistence of Hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses
    In: Journal of Virology Jg. 88 (2014) Nr. 15, S. 8656 - 8666
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/
  • Pei, Rong-Juan; Chen, Xin-Wen; Lu, Mengji
    Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways
    In: World Journal of Gastroenterology Jg. 20 (2014) Nr. 33, S. 11618 - 11629
    ISSN: 1007-9327
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Jia; Zhang, Ejuan; Ma, Zhiyong; Wu, Weimin; Kosinska, Anna; Zhang, Xiaoyong; Möller, Inga; Seiz, Pia; Glebe, Dieter; Wang, Baoju; Yang, Dongliang; Lu, Mengji; Roggendorf, Michael
    Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection
    In: PLoS Pathogens Jg. 10 (2014) Nr. 1, S. e1003856
    ISSN: 1553-7366; 1553-7374
    Online Volltext: dx.doi.org/ (Open Access)
  • Yang, Jingyi; Zhang, Ejuan; Liu, Fang; Zhang, Yan; Zhong, Maohua; Li, Yaoming; Zhou, Dihan; Chen, Yaoqing; Cao, Yuan; Xiao, Yang; He, Benxia; Yang, Yi; Sun, Ying; Lu, Mengji; Yan, Huimin
    Flagellins of salmonella typhi and nonpathogenic escherichia coli are differentially recognized through the NLRC4 pathway in macrophages
    In: Journal of Innate Immunity Jg. 6 (2014) Nr. 1, S. 47 - 57
    ISSN: 1662-8128
    Online Volltext: dx.doi.org/
  • Zhang, Yijun; Zhang, Yongmei; Kang, Yaoyue; Wang, Jinyu; Liu, Hongyan; Zhu, Haoxiang; Qin, Yanli; Mao, Richeng; Lin, Xu; Lu, Mengji; Zhang, Jiming
    Generation of a human hepatoma cell line supporting efficient replication of a lamivudine resistant hepatitis B virus
    In: Journal of Virological Methods Jg. 201 (2014) S. 51 - 56
    ISSN: 0166-0934
    Online Volltext: dx.doi.org/
  • Wang, Junzhong; Wang, Baoju; Huang, Shunmei; Song, Zhitao; Wu, Jun; Zhang, Ejuan; Zhu, Zhenni; Zhu, Bin; Yin, Ying; Lin, Yong; Xu, Yang; Zheng, Xin; Lu, Mengji; Yang, Dongliang
    Immunosuppressive drugs modulate the replication of hepatitis B virus (HBV) in a hydrodynamic injection mouse model
    In: PLoS ONE Jg. 9 (2014) Nr. 1, S. 85832
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Lu, Mengji; Wen, Yumei
    Interaction of viruses with host immune system and immunomodulation in chronic viral infections
    In: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 1 - 2
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Pei, Ronjuan; Qin, Bo; Zhang, Xiaoyong; Zhu, Wandi; Kemper, Thekla; Ma, Zhiong; Trippler, Martin; Schlaak, Jörg Friedrich; Chen, Xinwen; Lu, Mengji
    Interferon-induced proteins with tetratricopeptide repeats 1 and 2 are cellular factors that limit hepatitis B virus replication
    In: Journal of Innate Immunity Jg. 6 (2014) Nr. 2, S. 182 - 191
    ISSN: 1662-8128
    Online Volltext: dx.doi.org/
  • Xun, Yunhao; Zhang, Jijun; Pan, Qingchun; Mao, Richeng; Qin, Yanli; Liu, Hongyan; Zhang, Y.-M.; Yu, Yongsheng; Tang, Zhenghao; Lu, Mengji; Zang, Guoqing; Zhang, Jiming
    Metformin inhibits hepatitis B virus protein production and replication in human hepatoma cells
    In: Journal of Viral Hepatitis Jg. 21 (2014) Nr. 8, S. 597 - 603
    ISSN: 1365-2893
    Online Volltext: dx.doi.org/
  • Xu, Leibo; Beckebaum, Susanne; Iacob, Speranta; Wu, Gang; Kaiser, Gernot Maximil; Radtke, Arnold; Liu, Chao; Kabar, Iyad; Schmidt, Hartmut H; Zhang, Xiaoyong; Lu, Mengji; Cicinnati, Vito
    MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity
    In: Journal of Hepatology Jg. 60 (2014) Nr. 3, S. 590 - 598
    ISSN: 0168-8278
    Online Volltext: dx.doi.org/
  • Jiang, M.; Bröring, Ruth; Trippler, M.; Wu, J.; Zhang, E.; Zhang, X.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    MicroRNA-155 controls Toll-like receptor 3- and hepatitis C virus-induced immune responses in the liver
    In: Journal of Viral Hepatitis Jg. 21 (2014) Nr. 2, S. 99 - 110
    ISSN: 1352-0504; 1365-2893
    Online Volltext: dx.doi.org/
  • Liu, Jia; Kosinska, Anna; Lu, Mengji; Roggendorf, Michael
    New therapeutic vaccination strategies for the treatment of chronic hepatitis B
    In: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 10 - 16
    ISSN: 1995-820X; 1674-0769
    Online Volltext: dx.doi.org/
  • Meng, Zhongji; Ma, Zhiyong; Zhang, Ejuan; Kosinska, Anna D.; Liu, Jia; Zhang, Xiaoyong; Zhou, Tianlun; Wu, Jun; Dahmen, Uta; Dirsch, Olaf; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji
    Novel woodchuck hepatitis virus (WHV) transgene mouse models show sex-dependent WHV replicative activity and development of spontaneous immune responses to WHV proteins
    In: Journal of Virology Jg. 88 (2014) Nr. 3, S. 1573 - 1581
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/
  • Zhu, Wandi; Pei, Rongjuan; Jin, Rui; Hu, Xue; Zhou, Yuan; Wang, Yun; Wu, Chunchen; Lu, Mengji; Chen, Xinwen
    Nuclear receptor 4 group A member 1 determines hepatitis C virus entry efficiency through the regulation of cellular receptor and apolipoprotein E expression
    In: Journal of General Virology Jg. 95 (2014) S. 1510 - 1521
    ISSN: 0022-1317
    Online Volltext: dx.doi.org/
  • Wang, Baoju; Zhu, Zhenni; Zhu, Bin; Wang, Junzhong; Song, Zhitao; Huang, Shunmei; Fan, Wei; Tao, Yuanqing; Wang, Zhongdong; Wang, Hu; Lu, Mengji; Yang, Dongliang
    Nucleoside analogues alone or combined with vaccination prevent hepadnavirus viremia and induce protective immunity : Alternative strategy for hepatitis B virus post-exposure prophylaxis
    In: Antiviral Research Jg. 105 (2014) Nr. 1, S. 118 - 125
    ISSN: 1872-9096
    Online Volltext: dx.doi.org/
  • Hu, Jing; Liu, Jia; Yang, Dongliang; Lu, Mengji; Yin, Jian
    Physiological roles of asialoglycoprotein receptors (ASGPRs) variants and recent advances in hepatic-targeted delivery of therapeutic molecules via ASGPRs
    In: Protein & Peptide Letters Jg. 21 (2014) Nr. 10, S. 1025 - 1030
    ISSN: 0929-8665; 1875-5305
    Online Volltext: dx.doi.org/
  • Wu, Jun; Huang, Shunmei; Zhao, Xiaoli; Chen, Minfei; Lin, Yong; Xia, Youchen; Sun, Chan; Yang, Xuecheng; Wang, Junzhong; Guo, Yan; Song, Jingjiao; Zhang, Ejuan; Wang, Baoju; Zheng, Xin; Schlaak, Jörg Friedrich; Lu, Mengji; Yang, Dongliang
    Poly(I:C) Treatment Leads to Interferon-Dependent Clearance of Hepatitis B Virus in a Hydrodynamic Injection Mouse Model
    In: Journal of Virology Jg. 88 (2014) Nr. 18, S. 10421 - 10431
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/
  • Pei, Ronjuan; Grund, Sebastian; Verheyen, Jens; Esser, Stefan; Chen, Xinwen; Lu, Mengji
    Spontaneous reactivation of hepatitis B virus replication in an HIV coinfected patient with isolated anti-Hepatitis B core antibodies
    In: Virology Journal Jg. 11 (2014) Nr. 1, S. 9
    ISSN: 1743-422X
    Online Volltext: dx.doi.org/ (Open Access)
  • Song, Jingjiao; Zhou, Yun; Li, Sheng; Wang, Baoju; Zheng, Xin; Wu, Jun; Gibbert, Kathrin; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang
    Susceptibility of Different Hepatitis B Virus Isolates to Interferon-Alpha in a Mouse Model Based on Hydrodynamic Injection
    In: PLoS ONE Jg. 9 (2014) Nr. 3, S. e90977
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Jiang, M; Bröring, Ruth; Trippler, M; Poggenpohl, L; Fiedler, Melanie; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Toll-like receptor-mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen
    In: Journal of Viral Hepatitis Jg. 21 (2014) Nr. 12, S. 860 - 872
    ISSN: 1352-0504; 1365-2893
    Online Volltext: dx.doi.org/
  • Wu, Chunchen; Shi, Hui; Lu, Mengji; Xu, Yang; Chen, Xinwen
    A case of hepatitis B reactivation in an anti-HBs positive, anti-HBc positive non-Hodgkin’s lymphoma patient
    In: Virologica Sinica Jg. 28 (2013) Nr. 1, S. 49 - 52
    ISSN: 1674-0769; 1995-820X
    Online Volltext: dx.doi.org/
  • Kosinska, Anna D.; Zhang, Ejuan; Johrden, Lena; Liu, Jia; Seiz, Pia L.; Zhang, Xiaoyong; Ma, Zhiyong; Kemper, Thekla; Fiedler, Melanie; Glebe, Dieter; Wildner, Oliver; Dittmer, Ulf; Lu, Mengji; Roggendorf, Michael
    Combination of DNA Prime - Adenovirus Boost Immunization with Entecavir Elicits Sustained Control of Chronic Hepatitis B in the Woodchuck Model
    In: PLoS Pathogens Jg. 9 (2013) Nr. 6, S. e100339
    ISSN: 1553-7374
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, X.; Kosinska, A.; Wang, B.; Seiz, P.; Lu, Mengji; Yang, D.; Zhang, E.; Möller, I.; Liu, J.; Ma, Z.; Glebe, D.; Roggendorf, Michael
    Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD1/PD-L1 blockade in chronic hepadnaviral infection
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S160
    ISSN: 1600-0641
    Online Volltext: dx.doi.org/
  • Chen, Ming-Fa; Lin, Yong; Xia, You-Chen; Sun, Chan; Feng, Xue-Mei; Lu, Mengji; Yang, Dong-Liang; Wu, Jun
    Establishment and application of hepatitis B virus persistent replication model in IFNAR⁻/⁻ mouse
    In: Journal of Huazhong University of Science and Technology Jg. 33 (2013) Nr. 3, S. 392 - 397
    ISSN: 1672-0733; 1993-1352
    Online Volltext: dx.doi.org/
  • Chen, Jieliang; Wu, Min; Zhang, Xiaonan; Zhang, Wen; Zhang, Zhanqing; Chen, Lixian; He, Jing; Zheng, Ye; Chen, Cuncun; Wang, Fan; Hu, Yunwen; Zhou, Xiaohui; Wang, Cong; Xu, Yang; Lu, Mengji; Yuan, Zhenghong
    Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ
    In: Hepatology Jg. 57 (2013) Nr. 2, S. 470 - 482
    ISSN: 1527-3350
    Online Volltext: dx.doi.org/
  • Li, Lei; Shen, Hong; Li, Anyi; Zhang, Zhenhua; Wang, Baoju; Wang, Junzhong; Zheng, Xin; Wu, Jun; Yang, Dongliang; Lu, Mengji; Song, Jingjiao
    Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B
    In: Virology Journal Jg. 10 (2013) S. 214
    ISSN: 1743-422X
    Online Volltext: dx.doi.org/ (Open Access)
  • Yang, Yinke; Zhang, Xiaoyong; Zhang, Chunyan; Tao, Yuanqing; Fan, Wei; Wang, Zhongdong; Wang, Hu; Lu, Mengji; Yang, Dongliang; Fiedler, Melanie; Wang, Baoju
    Molecular characterization of woodchuck CD4 (wCD4) and production of a depletion monoclonal antibody against wCD4
    In: Molecular Immunology Jg. 56 (2013) Nr. 1/2, S. 64 - 71
    ISSN: 1872-9142; 0161-5890
    Online Volltext: dx.doi.org/
  • Zhu, B.; Yang, D.; Wang, Z.; Lu, Mengji; Fan, W.; Tao, Y.; Wang, B.; Huang, S.; Song, Z.; Zhu, Z.; Wang, H.
    Nucleoside analogues alone or combined with vaccination prevent WHV infection and induce protective immunity IMMUNITY : new strategy for HBV post-exposure prophylaxis
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S164 - S165
    ISSN: 1600-0641
    Online Volltext: dx.doi.org/
  • Lu, Mengji; Wang, B.; Pan, D.; Wu, W.; Xu, Y.; Yang, D.; Lin, Y.
    Persistence of chimeric Hepatitis B viruses in the hydrodynamic injection mouse model
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S165
    ISSN: 1600-0641
    Online Volltext: dx.doi.org/
  • Qin, Bo; Pei, RongJuan; He, TingTing; Huang, ZhaoHui; Pan, GuoShao; Tu, ChunYu; Lu, Mengji; Chen, XinWen
    Polymerase mutations rtN238R, rtT240Y and rtN248H of hepatitis B virus decrease susceptibility to adefovir
    In: Chinese Science Bulletin Jg. 58 (2013) Nr. 15, S. 1760 - 1766
    ISSN: 1861-9541; 1001-6538; 0250-7862
    Online Volltext: dx.doi.org/ (Open Access)
  • Fiedler, Melanie; Kosinska, Anna; Schumann, Alexandra; Brovko, Olena; Walker, Andreas; Lu, Mengji; Johrden, Lena; Mayer, Anja; Wildner, Oliver; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus
    In: Journal of Virology Jg. 87 (2013) Nr. 13, S. 7708 - 7716
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/
  • Meng, Zhongji; Zhang, Xiaoyong; Wu, Jun; Pei, Rongjuan; Xu, Yang; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji
    RNAi induces innate immunity through multiple cellular signaling pathways
    In: PLoS ONE Jg. 8 (2013) Nr. 5, e 64708
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Huang, S.; Wang, J.; Song, Z.; Yang, D.; Zhu, Z.; Feng, X.; Lu, Mengji; Zhu, B.; Wang, B.
    Rapamycin modulates the course of Hepatitis B Virus (HBV) infection in hydrodynamic injection mouse model : the role of Treg in HBV persistence
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S156 - S157
    ISSN: 1600-0641
    Online Volltext: dx.doi.org/
  • Lu, Mengji; Zhang, X.; Deng, W.; Li, B.; Hou, J.; Liu, H.
    Regulation of HBV replication bymicroRNA-449a through targeting creb5 in hepatoma cells
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S165
    ISSN: 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, Jia; Jiang, Min; Ma, Zhiyong; Dietze, Kirsten; Zelinskyy, Gennadiy; Yang, Dongliang; Dittmer, Ulf; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro
    In: The Journal of Immunology Jg. 191 (2013) Nr. 12, S. 6178 - 6190
    ISSN: 1550-6606
    Online Volltext: dx.doi.org/
  • Qin, Bo; Budeus, Bettina; Cao, Liang; Wu, Chunchen; Wang, Yun; Zhang, Xiaoyong; Rayner, Simon; Hoffmann, Daniel; Lu, Mengji; Chen, Xinwen
    The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    In: Antiviral Research Jg. 97 (2013) Nr. 2, S. 93 - 100
    ISSN: 0166-3542; 1872-9096
    Online Volltext: dx.doi.org/
  • Wu, Chunchen; Shi, Hui; Wang, Yun; Lu, Mengji; Xu, Yang; Chen, Xinwen
    A case of hepatitis B reactivation due to the hepatitis B virus escape mutant in a patient undergoing chemotherapy
    In: Virologica Sinica Jg. 27 (2012) Nr. 6, S. 369 - 372
    ISSN: 1674-0769; 1995-820X
    Online Volltext: dx.doi.org/
  • Wu, Chunchen; Deng, Wanyu; Deng, Liu; Cao, Liang; Qin, Bo; Li, Songxia; Wang, Yun; Pei, Rongjuan; Yang, Dongliang; Lu, Mengji; Chen, Xinwen
    Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg) determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance
    In: Journal of Virology Jg. 86 (2012) Nr. 8, S. 4658 - 4669
    ISSN: 1098-5514; 0022-538X
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Song; Pei, Rongjuan; Guo, Min; Han, Qingxia; Lai, Juan; Wang, Yun; Wu, Chunchen; Zhou, Yuan; Lu, Mengji; Chen, Xinwen
    Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly
    In: Journal of Virology Jg. 86 (2012) Nr. 23, S. 13025 - 13037
    ISSN: 0022-538X; 1098-5514
    Online Volltext: dx.doi.org/
  • Kosinska, Anna D.; Johrden, Lena; Zhang, Ejuan; Fiedler, Melanie; Mayer, Anja; Wildner, Oliver; Lu, Mengji; Roggendorf, Michael
    DNA Prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model
    In: Journal of Virology Jg. 86 (2012) Nr. 17, S. 9297 - 9310
    ISSN: 0022-538X; 1098-5514
    Online Volltext: dx.doi.org/
  • Sallam, T.A.; Raja'a, Y.A.; Bahaj, S.; Al-Shami, A.M.; Lu, Mengji; Roggendorf, Michael; Tong, C.Y.W.
    Hepatitis B virus carrier rate, prevalence and susceptibility and impact of immunization program among households in the city of Taiz, Yemen
    In: Vaccine Jg. 30 (2012) Nr. 37, S. 5564 - 5568
    ISSN: 1873-2518; 0264-410X; 1358-8745
    Online Volltext: dx.doi.org/
  • Zhu, Wenbo; Wu, Chunchen; Deng, Wanyu; Pei, Rongjun; Wang, Yun; Cao, Liang; Qin, Bo; Lu, Mengji; Chen, Xinwen
    Inhibition of the HCV Core Protein on the Immune Response to HBV Surface Antigen and on HBV Gene Expression and Replication In Vivo
    In: PLoS ONE Jg. 7 (2012) Nr. 9, S. e45146
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Fan, Hebin; Zhu, Zhenni; Wang, Yang; Zhang, Xiaoyong; Lu, Yinping; Tao, Yuanqing; Fan, Wei; Wang, Zhongdong; Wang, Hu; Roggendorf, Micheal; Lu, Mengji; Wang, Baoju; Yang, Dongliang
    Molecular characterization of the type I IFN receptor in two woodchuck species and detection of its expression in liver samples from woodchucks infected with woodchuck hepatitis virus (WHV)
    In: Cytokine Jg. 60 (2012) Nr. 1, S. 179 - 185
    ISSN: 1043-4666; 1096-0023
    Online Volltext: dx.doi.org/
  • Jiang, Min; Liu, Jia; Zhang, Ejuan; Meng, Zhongji; Wang, Baoju; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Molecular characterization of woodchuck interleukin-10 receptor and enhanced function of specific T cells from chronically infected woodchucks following its blockade
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 35 (2012) Nr. 6, S. 563 - 573
    ISSN: 0147-9571; 1878-1667
    Online Volltext: dx.doi.org/
  • Zhang, Xiaoyong; Kraft, Anke; Bröring, Ruth; Schlaak, Jörg Friedrich; Dittmer, Ulf; Lu, Mengji
    Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections
    In: Expert Opinion on Drug Discovery Jg. 7 (2012) Nr. 7, S. 597 - 611
    ISSN: 1746-045X; 1746-0441
    Online Volltext: dx.doi.org/
  • Yang, Yinke; Wang, Baoju; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Prokaryotic expression of woodchuck cytotoxic T lymphocyte antigen 4 (wCTLA-4) and preparation of polyclonal antibody to wCTLA-4
    In: Protein Expression and Purification Jg. 81 (2012) Nr. 2, S. 181 - 185
    ISSN: 1046-5928
    Online Volltext: dx.doi.org/
  • Pei, Rongjuan; Zhang, Xiaoyong; Xu, Song; Meng, Zhongji; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen
    Regulation of Hepatitis C virus replication and gene expression by the MAPK-ERK pathway
    In: Virologica Sinica Jg. 27 (2012) Nr. 5, S. 278 - 285
    ISSN: 1674-0769; 1995-820X
    Online Volltext: dx.doi.org/
  • Zhang, Xiaoyong; Ma, Zhiyong; Liu, Hongyan; Liu, Jia; Meng, Zhongji; Bröring, Ruth; Yang, Dongliang; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Role of Toll-like receptor 2 in the immune response against hepadnaviral infection
    In: Journal of Hepatology Jg. 57 (2012) Nr. 3, S. 522 - 528
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Fang, Haoshu; Liu, Anding; Dirsch, Olaf; Sun, Jian; Jin, Hao; Lu, Mengji; Yang, Dongliang; Dahmen, Uta
    Serum LBP levels reflect the impaired synthetic capacity of the remnant liver after partial hepatectomy in rats
    In: Journal of Immunological Methods Jg. 382 (2012) Nr. 1-2, S. 68 - 75
    ISSN: 1872-7905; 0022-1759
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Montag, Mario; Jiang, Min; Lu, Mengji; Sowa, Jan-Peter; Kleinehr, Kathrin; Gerken, Guido; Schlaak, Jörg Friedrich
    Corticosteroids shift the Toll-like receptor response pattern of primary-isolated murine liver cells from an inflammatory to an anti-inflammatory state
    In: International Immunology Jg. 23 (2011) Nr. 9, S. 537 - 544
    ISSN: 0953-8178; 1460-2377
    Online Volltext: dx.doi.org/
  • Yin, Ying; Wu, Chunchen; Song, Jingjiao; Wang, Junzhong; Zhang, Ejuan; Liu, Hongyan; Yang, Dongliang; Chen, Xinwen; Lu, Mengji; Xu, Yang
    DNA Immunization with Fusion of CTLA-4 to Hepatitis B Virus (HBV) Core Protein Enhanced Th2 Type Responses and Cleared HBV with an Accelerated Kinetic
    In: PLoS ONE Jg. 6 (2011) Nr. 7, S. 0022524
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhang, Zhenhuan; Li, Lei; Zhao, Xiping; Glebe, Dieter; Bremer, Corinna M.; Zhang, Zheng Mao; Tian, Yong Jun; Wang, Bao Ju; Yang, Yinke; Gerlich, Wolfram Hubert; Roggendorf, Michael; Li, Xu; Lu, Mengji; Yang, Dong Liang
    Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance
    In: Journal of Viral Hepatitis Jg. 18 (2011) Nr. 6, S. 424 - 433
    ISSN: 1352-0504; 1365-2893
    Online Volltext: dx.doi.org/
  • Wang, Bao-Ju; Tian, Yong-Jun; Meng, Zhong-Ji; Jiang, Min; Wei, Bo-Qing; Tao, Yuan-Qing; Fan, Wei; Li, An-Yi; Bao, Jun-Jie; Li, Xin-Yu; Zhang, Zheng-Mao; Wang, Zhong-Dong; Wang, Hu; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Establishing a new animal model for hepadnaviral infection : Susceptibility of Chinese Marmota-species to woodchuck hepatitis virus infection
    In: Journal of General Virology Jg. 92 (2011) Nr. 3, S. 681 - 691
    ISSN: 0022-1317; 1465-2099
    Online Volltext: dx.doi.org/ (Open Access)
  • Pei, Rongjuan; Chen, Honghe; Lu, Lu; Zhu, Wandi; Beckebaum, Susanne; Cicinnati, Vito; Lu, Mengji; Chen, Xinwen
    Hepatitis C virus infection induces the expression of amphiregulin, a factor related to the activation of cellular survival pathways and required for efficient viral assembly
    In: Journal of General Virology Jg. 92 (2011) Nr. 10, S. 2237 - 2248
    ISSN: 0022-1317; 1465-2099
    Online Volltext: dx.doi.org/
  • Wang, Bao-Ju; Bao, Jun-Jie; Wang, Jun-Zhong; Wang, Yang; Jiang, Min; Xing, Ming-You; Zhang, Wan-Guang; Qi, Jun-Ying; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma
    In: World Journal of Gastroenterology Jg. 17 (2011) Nr. 28, S. 3322 - 3329
    ISSN: 1007-9327
    Online Volltext: dx.doi.org/
  • Liu, Min; Hao, Youhua; Ding, Honghui; Yang, Dongliang; Lu, Mengji
    Interleukin-10 is expressed in HepG2.2.15 cells and regulated by STAT1 pathway
    In: Journal of Huazhong University of Science and Technology Jg. 31 (2011) Nr. 5, S. 625 - 631
    ISSN: 0257-716X
    Online Volltext: dx.doi.org/
  • Zhang, Xiaoyong; Zhang, Ejuan; Ma, Zhiyong; Pei, Rongjuan; Jiang, Min; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1
    In: Hepatology Jg. 53 (2011) Nr. 5, S. 1476 - 1485
    ISSN: 0270-9139; 1527-3350
    Online Volltext: dx.doi.org/ (Open Access)
  • Bröring, Ruth; Lu, Mengji; Schlaak, Jörg Friedrich; Schlaak, Joerg F.
    Role of Toll-like receptors in liver health and disease
    In: Clinical Science Jg. 121 (2011) Nr. 10, S. 415 - 426
    ISSN: 1470-8736; 0143-5221; 0301-0538; 0143-5221; 0009-9287
    Online Volltext: dx.doi.org/
  • Xu, Yang; Köck, Josef; Lu, Yinping; Yang, Dongliang; Lu, Mengji; Zhao, Xiping
    Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 34 (2011) Nr. 4, S. 361 - 368
    ISSN: 1878-1667
    Online Volltext: dx.doi.org/
  • Zhang, Ejuan; Zhang, Xiaoyong; Liu, Jia; Wang, Baoju; Tian, Yongjun; Kosinska, Anna D.; Ma, Zhiyong; Xu, Yang; Dittmer, Ulf; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    The Expression of PD-1 Ligands and Their Involvement in Regulation of T Cell Functions in Acute and Chronic Woodchuck Hepatitis Virus Infection
    In: PLoS ONE Jg. 6 (2011) Nr. 10, S. 0026196
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Zelinskyy, Gennadiy; Myers, Lara; Dietze, Kirsten; Gibbert, Kathrin; Roggendorf, Michael; Liu, Jia; Lu, Mengji; Kraft, Anke R.; Teichgräber, Volker; Hasenkrug, Kim J.; Dittmer, Ulf
    Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication
    In: The Journal of Immunology Jg. 187 (2011) Nr. 7, S. 3730 - 3737
    ISSN: 1550-6606; 0022-1767
    Online Volltext: dx.doi.org/
  • Zhang, X.; Zhang, E.; Meng, Z.; Ma, Z.; Schlaak, Jörg Friedrich; Lu, Mengji
    110 Modulation of HBV replication and cellular gene expression by microrna-1
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S49 - S50
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Wu, J.; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    627 HBV suppresses TLR signaling and the crosstalk to the adaptive immune system in murine and human cells
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S246
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, Jia; Hu, Bin; Yang, Yan; Ma, Zhiyong; Yu, Yuan; Liu, Shenpei; Wang, Baoju; Zhao, Xiping; Lu, Mengji; Yang, Dongliang
    A new splice variant of the major subunit of human asialoglycoprotein receptor encodes a secreted form in hepatocytes
    In: PLoS ONE Jg. 5 (2010) Nr. 9,
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Chunchen; Zhang, Xiaoyong; Tian, Zhang; Song, Jianhua; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen; Tian, Y.
    Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
    In: Journal of General Virology Jg. 91 (2010) Nr. 2, S. 483 - 492
    ISSN: 1465-2099; 0022-1317
    Online Volltext: dx.doi.org/
  • Liu, Jia; Yang, Yan; Hu, Bin; Ma, Zhi-Yong; Huang, Hong-Ping; Yu, Yuan; Liu, Shen-Pei; Lu, Mengji; Yang, Dong-Liang
    Development of HBsAg-binding aptamers that bind HepG2.2.15 cells via HBV surface antigen
    In: Virologica Sinica Jg. 25 (2010) Nr. 1, S. 27 - 35
    ISSN: 1995-820X
    Online Volltext: dx.doi.org/
  • Hu, Bin; Yang, Yan; Liu, Jia; Ma, Zhiyong; Huang, Hongping; Liu, Shenpei; Yu, Yuan; Hao, Youhua; Wang, Baoju; Lu, Mengji; Yang, Dongliang
    Establishment of a functional cell line expressing both subunits of H1a and H2c of human hepatocyte surface molecule ASGPR
    In: Journal of Huazhong University of Science and Technology Jg. 30 (2010) Nr. 5, S. 556 - 561
    ISSN: 0257-716X; 1672-0733
    Online Volltext: dx.doi.org/
  • Li, Yanmei; Chen, Jizheng; Wu, Chunchen; Wang, Linding; Lu, Mengji; Chen, Xinwen
    Hepatitis B virus/hepatitis C virus upregulate angiopoietin-2 expression through mitogen-activated protein kinase pathway
    In: Hepatology Research Jg. 40 (2010) Nr. 10, S. 1022 - 1033
    ISSN: 1872-034X; 1386-6346
    Online Volltext: dx.doi.org/
  • Shen, Qingli; Cicinnati, Vito; Zhang, Xiaoyong; Iacob, Speranta; Weber, Frank; Sotiropoulos, Georgios; Radtke, Arnold; Lu, Mengji; Paul, Andreas; Gerken, Guido; Beckebaum, Susanne
    Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
    In: Molecular Cancer Jg. 9 (2010) S. 227
    ISSN: 1476-4598
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhu, Wenbo; Chang, Yanzi; Wu, Chunchen; Han, Qingxia; Pei, Rongjuan; Lu, Mengji; Chen, Xinwen
    The Wild-Type Hepatitis C Virus Core Inhibits Initiation of Antigen-Specific T- and B-Cell Immune Responses in BALB/c Mice
    In: Clinical and Vaccine Immunology Jg. 17 (2010) Nr. 7, S. 1139 - 1147
    ISSN: 1556-6811; 1556-679X; 1098-6588; 1071-412X
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Zhang, Xiaozhen; Kottilil, Shyam; Trippler, Martin; Jiang, Min; Lu, Mengji; Gerken, Guido; Schlaak, Jörg Friedrich
    The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response
    In: Gut Jg. 59 (2010) Nr. 8, S. 1111 - 1119
    ISSN: 1468-3288; 0017-5749
    Online Volltext: dx.doi.org/
  • Roggendorf, Michael; Yang, D.; Lu, Mengji
    The woodchuck : A model for therapeutic vaccination against hepadnaviral infection
    In: Pathologie Biologie Jg. 58 (2010) Nr. 4, S. 308 - 314
    ISSN: 0369-8114; 1768-3114
    Online Volltext: dx.doi.org/
  • Wu, Jun; Meng, Zhongji; Jiang, Min; Zhang, Ejuan; Trippler, Martin; Bröring, Ruth; Bucchi, Agnes; Krux, Frank; Dittmer, Ulf; Yang, Dongliang; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific
    In: Immunology Jg. 129 (2010) Nr. 3, S. 363 - 374
    ISSN: 1365-2567; 0019-2805
    Online Volltext: dx.doi.org/
  • Lu, Mengji; Viazov, Sergey; Dittmer, Ulf; Roggendorf, Michael; aus dem Siepen, Marc
    Chronische Infektionen : ein Versagen des Immunsystems
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 34 - 47
    ISSN: 1869-3881
    Online Volltext; Online Volltext (Open Access)
  • Lu, M.; Isogawa, M.; Hilken, Gero
    Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune response in mice and woodchucks.
    In: (J. Virol.) Jg. 79 (2005) Nr. 10, S. 6368 - 6376
  • Dahmen, Uta; Dirsch, Olaf; Li, Jun; Fiedler, Melanie; Lu, Mengji; Rispeter, Kai; Picucci, Martha; Broelsch, Christoph E.; Roggendorf, Michael
    Adoptive transfer of immunity : A new strategy to interfere with severe hepatitis virus reinfection after woodchuck liver transplantation
    In: Transplantation Jg. 77 (2004) Nr. 7, S. 965 - 972
    ISSN: 0041-1337; 1534-0608
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Rödicker, Florian; Salucci, Valentina; Lu, Mengji; Aurisicchio, Luigi; Dahmen, Uta; Jun, Li; Dirsch, Olaf; Pützer, Brigitte M.; Palombo, Fabio; Roggendorf, Michael
    Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-α) and IFN-γ : IFN-α but not IFN-γ reduces woodchuck hepatitis virus replication in chronic infection in vivo
    In: Journal of Virology Jg. 78 (2004) Nr. 18, S. 10111 - 10121
    ISSN: 0022-538X; 1098-5514
    Online Volltext: dx.doi.org/ (Open Access)
  • Zeng, X.; Weinberger, K.M.; Gehrke, R.; Isogawa, M.; Hilken, Gero; Kemper, T.; Xu, Y.; Yang, D.; Jilg, W.; Roggendorf, M.; Lu, M.
    Mutant hepatitis B virus surface antigen (HbsAg) are immunogenic but may have a change specificity.
    In: Virology Jg. 329 (2004) S. 454 - 464
  • Dahmen, Uta; Li, Jun; Dirsch, Olaf; Fiedler, Melanie; Lu, Mengji; Roggendorf, Michael; Broelsch, Christoph Erich
    A new model of hepatitis B virus reinfection : Liver transplantation in the woodchuck
    In: Transplantation Jg. 74 (2002) Nr. 3, S. 373 - 380
    ISSN: 0041-1337; 1534-0608
    Online Volltext: dx.doi.org/
  • Lu, M.; Lohrengel, B.; Hilken, Gero; Kemper, T.; Roggendorf, M.
    Woodchuck gamma interferon upregulates major histocompartibility complex class I transcription but is unable to deplete woodchuck hepatitis virus replication intermediatesand RNAs in persistently infected woodchuck primary hepatocytes.
    In: (J. Virol.) Jg. 76 (2002) Nr. 1, S. 58 - 67
  • Haupt, K.; Siegel, F.; Lu, M.; Yang, D.; Hilken, Gero; Mann, K.; Roggendorf, M.; Saller, B.
    Induction of a cellular and humoral Immune response against preprocalcitonin by genetic immunization: A potential new treatment for medullary thyroid carcinoma.
    In: Endocrinology Jg. 142 (2001) Nr. 3, S. 1017 - 1023
  • Lu, M.; Hilken, Gero; Dongliang, Y.; Kemper, T.; Roggendorf, M.
    Replication of naturally occurring Woodchuck Hepatitis Virus: Deletion Mutants in primary hepatocytes cultures and after transmission to naive woodchucks.
    In: (J. Virology) Jg. 75 (2001) Nr. 8, S. 3811 - 3818
  • Lu, M.; Siegel, F.; Hilken, Gero; Kemper, T.; Roggendorf, M.
    DNA vaccination against hepadnavirus in the woodchuck model: priming immune response to woodchuck hepatitis virus core antigen protects against WHV infections.
    In: (Arch. Dermatol. Res.) Jg. 294 (2000) Nr. 4, S. 212
  • Haupt, K.; Siegel, F.; Lu, M.; Saller, B.; Hilken, Gero; Yang, D.; Mann, K.; Roggendorf, M.
    The GM-CSF gene enhances the immune response induced by DNA immunization against the tumor associated antigen calcitonin.
    In: (Arch. Dermatol. Res.) Jg. 294 (2000) Nr. 4, S. 216
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Kemper, T.; Schirmbeck, R.; Reimann, J.; Roggendorf, M.
    Immunization of woodchucks with plasmids expressing Woodchuck Hepatitis Virus (WHV) core antigen and surface antigen suppresses WHV infection.
    In: (J. Virology) Jg. 73 (1999) Nr. 1, S. 281 - 289

    • Vorworte / Nachworte

  • Meng, Zhongji; Liu, Jia; Kosinska, Anna D.; Lu, Mengji
    Editorial: Targeting the Immune System to Treat Hepatitis B Virus Infection
    In: Frontiers in Immunology Jg. 13 (2022)
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Zhenhua, Zhu; Trippler, Martin; Real, Catherine Isabell; Werner, Melanie; Kemper, Thekla; Baba, Hideo Andreas; Treckmann, Jürgen-Walter; Paul, A.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji; Bröring, Ruth
    Hepatitis B virus entry in primary human hepatocytes initiates toll-like receptor 2-dependent immune signaling
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 793
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Anastasiou, Olympia E.; Westhaus, Sandra; Anspach, Marie Christine; Timmer, Lejla; Susser, Simone; Sarrazin, Christoph; Gerken, Guido; Keitel, Verena; Wedemeyer, Heiner; Lu, Mengji; Stindt, Jan; Ciesek, Sandra
    Sodium taurocholate cotransporting popypeptide variants modulate HDV entry according to their function as a bile acid transporter but do not influence the antiviral effect of Myrcludex-B
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 781
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, X.; Ge, J.; Huang, Z.; Sun, J.; Lu, Mengji; Hou, J.
    Expression and Function of Toll-Like Receptor 7 in Chronic Hepatitis B Patients Links to Antiviral Effect of PEG-IFN-A-2A Therapy
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S380 - S381
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, J.; Yang, D.; Lu, Mengji
    HBV Strengthens Intrahepatic Myeloid-Derived Cells Mediated T Cell Tolerance through TLR1/2 Induced Kupffer Cell Expansion and IL-10 Production
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S515
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Bröring, Ruth; Zhang, Z.; Trippler, M.; Real, C.; Werner, M.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji
    Hepatitis B virus activates toll-like receptor 2 signaling upon infection of primary human hepatocytes
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S394
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, J.; Xu, C.; Zheng, X.; Lu, Mengji; Yang, D.
    Increased TLR2 Expression in Peripheral CD4+T Cells Promotes TH17 Cells Responses and is Associated with Disease Aggravation of HBV-Related Acute-on-Chronic Liver Failure
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 Jg. 64 (2016) Nr. 2, Suppl., S. S307
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, X.; Liu, H.; Wang, B.; Ma, Z.; Zhang, J.; Yang, D.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Epigenetic control of Hepatitis B virus replication and farnesoid X receptor alpha expression by histone deacetylases 3
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Suppl. 2, S. S17
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, H.; Zhang, J.; Zhang, X.; Bleekmann, B.; Kemper, T.; Roggendorf, Michael; Dittmer, Ulf; Lu, Mengji
    Genomic analysis of the host response to hepatitis b virus infection
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S187
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Hepatitis B virus surface antigen suppresses innate and adaptive immune responses of murine and human liver cells
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S174
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Wu, J.; Zhang, E.; Zhang, X.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    TLR-3 dependent immunological properties of liver cells are controlled by anti-inflammatory cytokines through modulation of MIR-155 expression
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S302 - S303
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Liu, J.; Jiang, M.; Ma, Z.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand stimulated mouse liver endothelial cells produce IL-12 and trigger CD8+ T-Cell immunity
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S311
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Ma, Z.; Zhang, E.; Zhang, X.; Liu, J.; Lin, Y.; Wu, J.; Kosinska, A.; Dittmer, Ulf; Roggendorf, Michael; Yang, D.; Lu, Mengji
    TLR2 ligand PAM3CSK4 inhibits peptide-induced deletion of CD8 T cells to viral antigens in mouse model
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S312
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Wu, J.; Chen, M.; Xia, Y.; Sun, C.; Lin, Y.; Wang, J.; Guo, Y.; Wang, B.; Song, J.; Lu, Mengji; Yang, D.
    The clearance of Hepatitis B virus (HBV) n hydrodynamik injection mouse model by polyinosinic-polycytidylic acid (POLYIC) treatment is dependent on interferon-gamma
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona Jg. 56 (2012) Nr. Supplement 2, S. S319
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Meng, Z.; Zhang, E.; Zhang, X.; Kosinska, A.; Xu, Y.; Yang, D.; Zhou, T.; Mason, W.; Roggendorf, Michael; Lu, Mengji
    DNA vaccination induces WHS/CAG specific T Cell immune responses in the newly constructed WHV transgenic mouse model
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S441
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Wang, J. Z.; Wang, B. J.; Huang, S. M.; Wu, J.; Zhu, Z. N.; Zhu, B.; Ding, H. H.; Feng, X. M.; Yin, Y.; Roggendorf, Michael; Lu, Mengji; Yang, D. L.
    Immunosuppression modulates the course of hepatitis B virus (HBV) infection in hydrodynamic injection mouse model
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S127
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, X.; Ma, Z.; Wu, C.; Zhang, E.; Bröring, Ruth; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of HBV replication by cell cycle and differentiation related micrornas
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S448 - S449
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Schumann, A.; Kosinska, A.; Lu, Mengji; Johrden, L.; Wildner, O.; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects woodchucks from hepatitis D virus infection
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 Jg. 54 (2011) Nr. Suppl. 1, S. S439
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Xu, L.; Beckebaum, Susanne; Wu, G.; Zhang, X.; Lu, Mengji; Iacob, S.; Paul, Andreas; Gerken, Guido; Cicinnati, Vito R.;
    The putative tumor suppressor microrna-101 negatively regulates the polycomb group protein enhancer of zeste homolog 2 (EZH2) in human hepatocellular carcinoma cells
    46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011,
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S110
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Jiang, M.; Wu, J.; Zhang, E.; Meng, Z.; Trippler, M.; Bröring, Ruth; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    446 HCV/TLR3- dependent innate and adaptive immune functions of non-parenchymal liver cells are controlled by interleukin-10 and transforming growth factor beta
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S180
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Zhang, E.; Kosinska, A.; Zhang, X.; Meng, Z.; Xu, Y.; Yang, D.; Roggendorf, Michael; Lu, Mengji;
    637 Enhanced TH2 type immune response in DNA immunization by fusion of WCTLA-4 to woodchuck hepatitis core antigen
    International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver,
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S249
    ISSN: 0168-8278; 1600-0641
    Online Volltext: dx.doi.org/
  • Roggendorf, Michael; Ke, X.Y.; Yang, Y.; Yang, D.L.; Zhang, X.Y.; Meng, Z.J.; Kemper, T.; Wang, Q.J.; Lu, Mengji; Lu, L.;
    OL-022 The effect of double-stranded DNA on replication of hepatitis B virus and cellular signalling
    Fourth Ditan International Conference on Infectious Diseases - Changing Face of Infectious Diseases. 15-18 July 2010, Beijing,
    In: International Journal of Infectious Diseases Jg. 14 (2010) Nr. Suppl. 2, S. S10
    ISSN: 1878-3511; 1201-9712
    Online Volltext: dx.doi.org/ (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Liu, Jia; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Yang, Dongliang; Lu, Mengji
    Advanced Method for Isolation of Mouse Hepatocytes, Liver Sinusoidal Endothelial Cells, and Kupffer Cells
    In: Hepatitis B Virus: Methods and Protocols / Guo, Haitao; Cuconati, Andrea (Hrsg.) 2017, S. 249 - 258
    ISBN: 978-1-4939-6700-1
    Online Volltext: dx.doi.org/
  • Bauer, Dirk; Wasmuth, Susanne; Lu, Mengji; Heiligenhaus, Arnd
    Particle-mediated administration of plasmid DNA on corneas of BALB/c mice
    In: Biolistic DNA Delivery: Methods and Protocols / Sudowe, Stephan; Reske-Kunz, Angelika B. (Hrsg.) 2013, S. 215 - 220
    ISBN: 978-1-62703-109-7; 978-1-62703-110-3 ISSN: 1940-6029
    Online Volltext: dx.doi.org/
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, M.
    Protektion von Woodchucks gegen Woodchuckhepatitisvirus (WHV)-Infektion durch DNA-Immunisierung mit WHcAg- und WHsAg-exprimierenden Plasmiden.
    In: Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998, 1998, S. 30
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, M.
    Immunization of woodchucks with plasmids expressing Woodchuck Hepatitis Virus (WHV) core antigen and surface antigen confers protection from infection with WHV.
    In: Molecular Biology of Hepatitis B Viruses, Institut Pasteur, Paris. 21.-25.9.1997. 1997 O 62

    • Vorträge

  • Lu, Mengji; Hilken, Gero; Yang, D.; Roggendorf, Michael;
    Replikation von Deletionsmutanten des Woodchuck Hepatitis Virus (WHV) in primären Woodchuck Hepatitis Kulturen und in vivo nach einer Übertragung
    38. Tagung der GV-SOLAS, September 2000, Essen,
    (2000)