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Institut für Virologie der Medizinischen Fakultät
Anschrift
Virchowstr. 179 / Robert-Koch-Haus
45147 Essen

Funktionen

  • Universitätsprofessor/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Wang, Xueyu; Lin, Yong; Kemper, Thekla; Chen, Jieliang; Yuan, Zhenghong; Liu, Shi; Zhu, Ying; Bröring, Ruth; Lu, Mengji
    AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy
    In: Cellular Microbiology Jg. 22 (2020) Nr. 2,
    ISSN: 1462-5814; 1462-5822
  • Rojas-Sánchez, Leonardo; Zhang, Ejuan; Sokolova, Viktoriya; Zhong, Maohua; Yan, Hu; Lu, Mengji; Li, Qian; Yan, Huimin; Epple, Matthias
    Genetic immunization against hepatitis B virus with calcium phosphate nanoparticles in vitro and in vivo
    In: Acta Biomaterialia: Structure, property, function ; relationships in biomaterials (2020)
    ISSN: 1878-7568; 1742-7061
  • Xu, Ling; Liu, Jia; Lu, Mengji; Yang, Dongliang; Zheng, Xin
    Liver injury during highly pathogenic human coronavirus infections
    In: Liver International: official journal of the International Association for the Study of the Liver (2020)
    ISSN: 1478-3231; 1478-3223
  • Zhang, Ejuan; Yan, Hu; Li, Qian; Dittmer, Ulf; Yan, Huimin; Lu, Mengji
    Activation of the TLR signaling pathway in CD8+ T cells counteracts liver endothelial cell-induced T cell tolerance
    In: Cellular & Molecular Immunology Jg. 16 (2019) Nr. 9, S. 774 - 776
    ISSN: 2042-0226; 1672-7681
  • Yan, Yan; Chen, Renfang; Wang, Xu; Hu, Kai; Huang, Lihua; Lu, Mengji; Hu, Qinxue
    CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions in Viral Infection and Prevention
    In: Frontiers in Cell and Developmental Biology Jg. 7 (2019) S. 212
    ISSN: 2296-634X
  • Wu, Chunchen; Li, Baolin; Zhang, Xiaoyong; Zhao, Kaitao; Chen, Yingshan; Yuan, Yifei; Liu, Yan; Chen, Rongjuan; Xu, Dongping; Chen, Xinwen; Lu, Mengji
    Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs
    In: Virologica Sinica Jg. 34 (2019) Nr. 4, S. 377 - 385
    ISSN: 1995-820X; 1674-0769
  • Liu, Shi; Liu, Li; Xu, Gang; Cao, Zhongying; Wang, Qing; Li, Shun; Peng, Nanfang; Yin, Jingchuan; Yu, Haisheng; Li, Mengqi; Xia, Zhangchuan; Zhou, Li; Lin, Yong; Wang, Xueyu; Li, Qian; Zhu, Chengliang; Yang, Xuecheng; Wang, Jun; She, Yinglong; Lu, Mengji; Zhu, Ying
    Epigenetic Modification Is Regulated by the Interaction of Influenza A Virus Nonstructural Protein 1 with the De Novo DNA Methyltransferase DNMT3B and Subsequent Transport to the Cytoplasm for K48-Linked Polyubiquitination
    In: Journal of virology Jg. 93 (2019) Nr. 7,
    ISSN: 1098-5514
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Kemper, Thekla; Squire, Anthony; Gunzer, Matthias; Zhang, Jiming; Chen, Xinwen; Lu, Mengji
    Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components
    In: Protein & Cell Jg. 10 (2019) Nr. 1, S. 60 - 66
    ISSN: 1674-8018; 1674-800X
  • Liu, Yan; Zhou, Yi; Li, Xiaodong; Niu, Ming; Chen, Rongjuan; Shao, Jinman; Si, Lanlan; Luo, Dan; Lin, Yayun; Li, Le; Zhang, Kai; Xiao, Xiaohe; Xu, Zhihui; Liu, Min; Lu, Mengji; Zoulim, Fabien; Xu, Dongping
    Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice
    In: Emerging Microbes & Infections Jg. 8 (2019) Nr. 1, S. 354 - 365
    ISSN: 2222-1751
  • Wang, Jinyu; Li, Jing; Wu, Jingwen; Dong, Minhui; Shen, Zhongliang; Lin, Yong; Li, Fahong; Zhang, Yongmei; Mao, Richeng; Lu, Mengji; Zhang, Jiming
    Host Gene SEL1L Involved in Endoplasmic Reticulum-Associated Degradation Pathway Could Inhibit Hepatitis B Virus at RNA, DNA, and Protein Levels
    In: Frontiers in Microbiology Jg. 10 (2019)
    ISSN: 1664-302X
  • Zhang, Zhenhua; Wang, Changtai; Liu, Zhongping; Zou, Guizhou; Li, Jun; Lu, Mengji
    Host Genetic Determinants of Hepatitis B Virus Infection
    In: Frontiers in Genetics Jg. 10 (2019) S. 696
    ISSN: 1664-8021
  • Xu, Gang; Xia, Zhangchuan; Deng, Feiyan; Liu, Lin; Wang, Qiming; Yu, Yi; Wang, Fubing; Zhu, Chengliang; Liu, Weiyong; Cheng, Zhikui; Zhu, Ying; Zhou, Li; Zhang, Yi; Lu, Mengji; Liu, Shi
    Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex
    In: PLoS Pathogens Jg. 15 (2019) Nr. 8, S. 1008002
    ISSN: 1553-7374; 1553-7366
  • Yang, Shangqing; Wang, Lu; Pan, Wen; Bayer, Wibke; Thoens, Christine; Heim, Kathrin; Dittmer, Ulf; Timm, Jörg; Wang, Qin; Yu, Qing; Luo, Jinzhuo; Liu, Yanan; Hofmann, Maike; Thimme, Robert; Zhang, Xiaoyong; Chen, Hongtao; Wang, Hua; Feng, Xuemei; Yang, Xuecheng; Lu, Yinping; Lu, Mengji; Yang, Dongliang; Liu, Jia
    MMP2/MMP9-mediated CD100 shedding is crucial for inducing intrahepatic anti-HBV CD8 T cell responses and HBV clearance
    In: Journal of Hepatology Jg. 71 (2019) Nr. 4, S. 685 - 698
    ISSN: 1600-0641; 0168-8278
  • Yu, Haisheng; Li, Mengqi; He, Rui; Fang, Peining; Wang, Qiming; Yi, Yu; Wang, Fubing; Zhou, Li; Zhang, Yi; Chen, Aidong; Peng, Nanfang; Liu, Dan; Trilling, Mirko; Bröring, Ruth; Wiemer, Erik A.C.; Lu, Mengji; Zhu, Ying; Liu, Shi
    Major vault protein promotes hepatocellular carcinoma through targeting interferon regulatory factor 2 and decreasing p53 activity
    In: Hepatology: official journal of the American Association for the Study of Liver Diseases (2019)
    ISSN: 1527-3350; 0270-9139
  • Liu, Yan; Wu, Chunchen; Chen, Rongjuan; Li, Xiaodong; Xu, Zhihui; Li, Qi; Li, Le; Wang, Fu-Sheng; Yang, Dongliang; Lu, Mengji; Xu, Dongping
    Molecular cloning and phenotypic analysis of drug‑resistance mutants with relevant S‑region variants of HBV for a patient during 189‑month anti‑HBV treatment
    In: Antiviral Therapy: an official publication of the International Society for Antiviral Research Jg. 24 (2019) Nr. 4, S. 237 - 246
    ISSN: 2040-2058; 1359-6535
  • Wu, Jun; Han, Meihong; Li, Jia; Yang, Xiaoli; Zhen, Xin; Friedrich Schlaak, Joerg; Yang, Dongliang; Lu, Mengji
    Pattern recognition receptors and liver failure
    In: Critical Reviews in Immunology Jg. 39 (2019) Nr. 4, S. 289 - 311
    ISSN: 1040-8401; 2162-6472
  • Yao, Yongxuan; Yang, Bo; Chen, Yingshan; Wang, Hui; Hu, Xue; Zhou, Yuan; Gao, Xiuzhu; Lu, Mengji; Niu, Junqi; Wen, Zhe; Wu, Chunchen; Chen, Xinwen
    RNA-binding motif protein 24 (RBM24) is involved in pregenomic RNA packaging by mediating interaction between hepatitis B virus polymerase and the epsilon element
    In: Journal of Virology Jg. 93 (2019) Nr. 6, S. e02161 - 18
    ISSN: 0022-538X; 1098-5514
  • Lin, Yong; Wu, Chunchen; Wang, Xueyu; Liu, Shi; Kemper, Thekla; Li, Fahong; Squire, Anthony; Zhu, Ying; Zhang, Jiming; Chen, Xinwen; Lu, Mengji
    Synaptosomal-associated protein 29 is required for the autophagic degradation of hepatitis B virus
    In: The FASEB Journal Jg. 33 (2019) Nr. 5, S. 6023 - 6034
    ISSN: 1530-6860; 0892-6638
  • Zhang, Ejuan; Ma, Zhiyong; Li, Qian; Yan, Hu; Liu, Jia; Wu, Weimin; Guo, Jiabao; Zhang, Xiaoyong; Kirschning, Carsten Jürgen; Xu, Haifeng; Lang, Philipp A.; Yang, Dongliang; Dittmer, Ulf; Yan, Huimin; Lu, Mengji
    TLR2 stimulation increases cellular metabolism in CD8⁺ T cells and thereby enhances CD8⁺ T cell activation, function, and antiviral activity
    In: The Journal of Immunology Jg. 203 (2019) Nr. 11, S. 2872 - 2886
    ISSN: 1550-6606; 0022-1767; 1048-3233; 1047-7381
  • Li, Qian; Yan, Yan; Liu, Jia; Huang, Xuan; Zhang, Xiaoyong; Kirschning, Carsten Jürgen; Xu, Haifeng C.; Lang, Philipp A.; Dittmer, Ulf; Zhang, Ejuan; Lu, Mengji
    Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis
    In: Frontiers in Immunology Jg. 10 (2019) S. 2191
    ISSN: 1664-3224
  • Ma, Zhiyong; Zhang, Ejuan; Gao, Shicheng; Xiong, Yong; Lu, Mengji
    Toward a functional cure for hepatitis B: The rationale and challenges for therapeutic targeting of the b cell immune response
    In: Frontiers in Immunology Jg. 10 (2019) S. 2308
    ISSN: 1664-3224
  • Yang, Li; Liu, Feifei; Tong, Xiankun; Hoffmann, Daniel; Zuo, Jianping; Lu, Mengji
    Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and Perspectives
    In: ACS Infectious Diseases Jg. 5 (2019) Nr. 5, S. 713 - 724
    ISSN: 2373-8227
  • Schöneweis, Katrin; Motter, Neil; Roppert, Pia L.; Lu, Mengji; Wang, Baoju; Roehl, Ingo; Glebe, Dieter; Yang, Dongliang; Morrey, John D.; Roggendorf, Michael; Vaillant, Andrew
    Activity of nucleic acid polymers in rodent models of HBV infection
    In: Antiviral Research Jg. 149 (2018) S. 26 - 33
    ISSN: 1872-9096; 0166-3542
  • Li, Meng-Meng; Zhang, Wen-Jing; Weng, Xiu-Fang; Li, Ming-Yue; Liu, Jia; Xiong, Yan; Xiong, Shu-E; Zou, Cong-Cong; Wang, Hua; Lu, Mengji; Yang, Dong-Liang; Peng, Cheng; Zheng, Xin
    CD4 T cell loss and Th2 and Th17 bias are associated with the severity of severe fever with thrombocytopenia syndrome (SFTS)
    In: Clinical Immunology Jg. 195 (2018) S. 8 - 17
    ISSN: 1521-7035; 1521-6616
  • Zhu, Bin; Zhu, Zhenni; Wang, Junzhong; Huang, Shunmei; Li, Fanghui; Wang, Lu; Liu, Yanan; Yan, Qi; Zhou, Shunchang; Lu, Mengji; Yang, Dongliang; Wang, Baoju
    Chinese woodchucks with different susceptibility to WHV infection differ in their genetic background exemplified by cytochrome B and MHC-DRB molecules
    In: Virology Journal Jg. 15 (2018) Nr. 1, S. 101
    ISSN: 1743-422X
  • Li, Meng-Meng; Zhang, Wen-Jing; Liu, Jia; Li, Ming-Yue; Zhang, Yan-Fang; Xiong, Yan; Xiong, Shu-E; Zou, Cong-Cong; Xiong, Lei-Qun; Liang, Bo-Yun; Lu, Mengji; Yang, Dong-Liang; Peng, Cheng; Zheng, Xin
    Dynamic changes in the immunological characteristics of T lymphocytes in surviving patients with severe fever with thrombocytopenia syndrome (SFTS)
    In: International Journal of Infectious Diseases Jg. 70 (2018) S. 72 - 80
    ISSN: 1878-3511; 1201-9712
  • Wang, Qin; Pan, Wen; Liu, Yanan; Luo, Jinzhuo; Zhu, Dan; Lu, Yinping; Feng, Xuemei; Yang, Xuecheng; Dittmer, Ulf; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment
    In: Frontiers in Immunology Jg. 9 (2018) S. 219
    ISSN: 1664-3224
  • Wu, Chun-Chen; Chen, Ying-Shan; Cao, Liang; Chen, Xin-Wen; Lu, Mengji
    Hepatitis B virus infection : Defective surface antigen expression and pathogenesis
    In: World Journal of Gastroenterology Jg. 24 (2018) Nr. 31, S. 3488 - 3499
    ISSN: 1007-9327
  • Shen, Fang; Li, Yaming; Wang, Yang; Sozzi, Vitina; Revill, Peter A.; Liu, Jiangxia; Gao, Lu; Yang, Guang; Lu, Mengji; Sutter, Kathrin; Dittmer, Ulf; Chen, Jieliang; Yuan, Zhenghong
    Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotype
    In: Hepatology Jg. 67 (2018) Nr. 4, S. 1237 - 1252
    ISSN: 1527-3350; 0270-9139
  • Ma, Zhiyong; Cao, Qian; Xiong, Yong; Zhang, Ejuan; Lu, Mengji
    Interaction between Hepatitis B Virus and Toll-Like Receptors : current status and potential therapeutic use for chronic hepatitis B
    In: Vaccines Jg. 6 (2018) Nr. 1, S. 6
    ISSN: 2076-393X
  • Huang, Shunmei; Wu, Jun; Gao, Xiaoyan; Zou, Shi; Chen, Liwen; Yang, Xilang; Sun, Chan; Du, Yanqin; Zhu, Bin; Li, Jia; Yang, Xuecheng; Feng, Xuemei; Wu, Chunchen; Shi, Chunwei; Wang, Baoju; Lu, Yinping; Liu, Jia; Zheng, Xin; Gong, Feili; Lu, Mengji; Yang, Dongliang
    LSECs express functional NOD1 receptors : A role for NOD1 in LSEC maturation-induced T cell immunity in vitro
    In: Molecular Immunology Jg. 101 (2018) S. 167 - 175
    ISSN: 1872-9142; 0161-5890
  • Huang, Shunmei; Zou, Shi; Chen, Mingfa; Gao, Xiaoyan; Chen, Liwen; Yang, Xilang; Yu, Qing; Zhao, Xiaoli; Du, Yanqin; Yang, Xuecheng; Lin, Yong; Wang, Baoju; Lu, Yinping; Liu, Jia; Zheng, Xin; Gong, Feili; Lu, Mengji; Yang, Dongliang; Wu, Jun
    Local stimulation of liver sinusoidal endothelial cells with a NOD1 agonist activates t cells and suppresses hepatitis b virus replication in mice
    In: Journal of Immunology Jg. 200 (2018) Nr. 9, S. 3170 - 3179
    ISSN: 1550-6606; 0022-1767
  • Peng, Nanfang; Yang, Xuecheng; Zhu, Chengliang; Zhou, Li; Yu, Haisheng; Li, Mengqi; Lin, Yong; Wang, Xueyu; Li, Qian; She, Yinglong; Wang, Jun; Zhao, Qian; Lu, Mengji; Zhu, Ying; Liu, Shi
    MicroRNA-302 cluster downregulates enterovirus 71–Induced innate immune response by targeting KPNA2
    In: Journal of Immunology Jg. 201 (2018) Nr. 1, S. 145 - 156
    ISSN: 1550-6606; 0022-1767
  • Lin, Yong; Huang, Xuan; Wu, Jun; Liu, Jia; Chen, Mingfa; Ma, Zhiyong; Zhang, Ejuan; Liu, Yan; Huang, Shunmei; Li, Qian; Zhang, Xiaoyong; Hou, Jinlin; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Pre-activation of Toll-like receptor 2 enhances CD8⁺ T-cell responses and accelerates hepatitis B virus clearance in the mouse models
    In: Frontiers in Immunology Jg. 9 (2018) S. 1495
    ISSN: 1664-3224
  • Yao, Yongxuan; Yang, Bo; Cao, Huang; Zhao, Kaitao; Yuan, Yifei; Chen, Yingshan; Zhang, Zhenhua; Wang, Yun; Pei, Rongjuan; Chen, Jizheng; Hu, Xue; Zhou, Yuan; Lu, Mengji; Wu, Chunchen; Chen, Xinwen
    RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence article
    In: Emerging Microbes & Infections Jg. 7 (2018) S. 86
    ISSN: 2222-1751
  • Cao, Huang; Zhao, Kaitao; Yao, Yongxuan; Guo, Jing; Gao, Xiaoxiao; Yang, Qi; Guo, Min; Zhu, Wandi; Wang, Yun; Wu, Chunchen; Chen, Jizheng; Zhou, Yuan; Hu, Xue; Lu, Mengji; Chen, Xinwen; Pei, Rongjuan
    RNA binding protein 24 regulates the translation and replication of hepatitis C virus
    In: Protein and Cell Jg. 9 (2018) Nr. 11, S. 930 - 944
    ISSN: 1674-8018; 1674-800X
  • Du, Keye; Liu, Jia; Bröring, Ruth; Zhang, Xiaoyong; Yang, Dongliang; Dittmer, Ulf; Lu, Mengji
    Recent advances in the discovery and development of TLR ligands as novel therapeutics for chronic HBV and HIV infections
    In: Expert Opinion on Drug Discovery Jg. 13 (2018) Nr. 7, S. 661 - 670
    ISSN: 1746-045X; 1746-0441
  • Yang, Jingyi; Zhao, Yue; Li, Peng; Yang, Yi; Zhang, Ejuan; Zhong, Maohua; Li, Yaoming; Zhou, DIhan; Cao, Yuan; Lu, Mengji; Shao, Feng; Yan, Huimin
    Sequence determinants of specific pattern-recognition of bacterial ligands by the NAIP-NLRC4 inflammasome
    In: Cell Discovery Jg. 4 (2018) Nr. 1, S. 18
    ISSN: 2056-5968
  • Yang, Li; Lu, Mengji
    Small molecule inhibitors of hepatitis B virus nucleocapsid assembly : a new approach to treat chronic HBV infection
    In: Current Medicinal Chemistry Jg. 25 (2018) Nr. 7, S. 802 - 813
    ISSN: 1875-533X; 0929-8673
  • Liu, Jia; Yu, Qing; Wu, Weimin; Huang, Xuan; Bröring, Ruth; Werner, Melanie; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    TLR2 stimulation strengthens intrahepatic myeloid-derived cell-mediated T cell tolerance through inducing kupffer cell expansion and IL-10 production
    In: Journal of Immunology Jg. 200 (2018) Nr. 7, S. 2341 - 2351
    ISSN: 1550-6606; 0022-1767
  • Zhao, Kaitao; Liu, Shuhui; Chen, Yingshan; Yao, Yongxuan; Zhou, Ming; Yuan, Yifei; Wang, Yun; Pei, Rongjuan; Chen, Jizheng; Hu, Xue; Zhou, Yuan; Zhao, He; Lu, Mengji; Wu, Chunchen; Chen, Xinwen
    Upregulation of HBV transcription by sodium taurocholate cotransporting polypeptide at the postentry step is inhibited by the entry inhibitor Myrcludex B
    In: Emerging Microbes & Infections Jg. 7 (2018) S. 186
    ISSN: 2222-1751
  • Zhao, Kaitao; Wu, Chunchen; Yao, Yongxuan; Cao, Liang; Zhang, Zhenhua; Yuan, Yifei; Wang, Yun; Pei, Rongjuan; Chen, Jizheng; Hu, Xue; Zhou, Yuan; Lu, Mengji; Chen, Xinwen
    Ceruloplasmin inhibits the production of extracellular hepatitis B virions by targeting its middle surface protein
    In: Journal of General Virology Jg. 98 (2017) Nr. 6, S. 1410 - 1421
    ISSN: 1465-2099; 0022-1317
  • Zhang, Wenjing; Li, Mengmeng; Xiong, Shue; Wang, Hua; Xiong, Yan; Li, Mingyue; Lu, Mengji; Yang, Dongliang; Peng, Cheng; Zheng, Xin
    Decreased myeloid dendritic cells indicate a poor prognosis in patients with severe fever with thrombocytopenia syndrome
    In: International Journal of Infectious Diseases Jg. 54 (2017) S. 113 - 120
    ISSN: 1878-3511; 1201-9712
  • Zhou, Yun; Li, Sheng; Tang, Zongsheng; Xu, Chunli; Huang, Shunmei; Wu, Jun; Dittmer, Ulf; Dickow, Julia; Sutter, Kathrin; Lu, Mengji; Yang, Dongliang; Song, Jingjiao
    Different antiviral effects of IFNα and IFNβ in an HBV mouse model
    In: Immunobiology Jg. 222 (2017) Nr. 3, S. 562 - 570
    ISSN: 0171-2985; 1878-3279
  • Song, Jingjiao; Li, Sheng; Zhou, Yun; Liu, Jia; Francois, Sandra; Lu, Mengji; Yang, Dongliang; Dittmer, Ulf; Sutter, Kathrin
    Different antiviral effects of IFNα subtypes in a mouse model of HBV infection
    In: Scientific Reports Jg. 7 (2017) Nr. 1, S. 334
    ISSN: 2045-2322
  • Liu, Chao; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Ge, Jun; Li, Yongyin; Liao, Baolin; Sun, Jian; Peng, Jie; Lu, Mengji; Hou, Jinlin; Zhang, Xiaoyong
    Elevated expression of chemokine CXCL13 in chronic hepatitis B patients links to immune control during antiviral therapy
    In: Frontiers in Immunology Jg. 8 (2017) S. 323
    ISSN: 1664-3224
  • Liu, C.; Bröring, Ruth; Hideo, B.A.; Real, C.I.; Zhang, R.; Lu, Mengji; Gerken, Guido
    Hepatic expression of oncogenes Bmi1 and Dkk1 can be induced by treatment with hepatitis B virus particles or Lipopolysaccharide in vitro and is up-regulated in liver biopsies of patients with chronic HBV infection
    In: Journal of Hepatology Jg. 66 (2017) Nr. 1, S. S700
    ISSN: 0168-8278; 1600-0641
  • Zhang, Ruiyong; Real, Catherine I.; Liu, Chao; Baba, Hideo Andreas; Gerken, Guido; Lu, Mengji; Bröring, Ruth
    Hepatic expression of oncogenes Bmi1 and Dkk1 is up-regulated in hepatitis B virus surface antigen–transgenic mice and can be induced by treatment with HBV particles or lipopolysaccharides in vitro
    In: International Journal of Cancer Jg. 141 (2017) Nr. 2, S. 354 - 363
    ISSN: 0020-7136; 1097-0215
  • Wan, Yushun; Cao, Wei; Han, Tao; Ren, Sheng; Feng, Jian; Chen, TieLong; Wang, Jun; Bröring, Ruth; Lu, Mengji; Zhu, Ying
    Inducible Rubicon facilitates viral replication by antagonizing interferon production
    In: Cellular and Molecular Immunology Jg. 14 (2017) Nr. 7, S. 607 - 620
    ISSN: 1672-7681
  • Fang, Zhong; Roggendorf, Michael; Wang, Cong; Lin, Yong; Liu, Jia; Lu, Mengji; Dietze, Kirsten; Chen, Jieliang; Dittmer, Ulf; Yeh, Shiou-Hwei; Wu, Weimin; Kemper, Thekla; Kosinska, Anna D.; Lenart, Marzena; Yuan, Zhenghong; Pishraft-Sabet, Leila
    Low hepatitis B virus-specific T-cell response in males correlates with high regulatory T-cell numbers in murine models
    In: Hepatology Jg. 66 (2017) Nr. 1, S. 69 - 83
    ISSN: 1527-3350
  • Liu, Shuhui; Zhao, Kaitao; Su, Xi; Lu, Lu; Zhao, He; Zhang, Xianwen; Wang, Yun; Wu, Chunchen; Chen, Jizheng; Zhou, Yuan; Hu, Xue; Wang, Yanyi; Lu, Mengji; Chen, Xinwen; Pei, Rongjuan
    MITA/STING and its alternative splicing isoform MRP restrict hepatitis B virus replication
    In: PLoS One Jg. 12 (2017) Nr. 1, S. e0169701
    ISSN: 1932-6203
  • Deng, Wanyu; Zhang, Xiaoyong; Ma, Zhiyong; Lin, Yong; Lu, Mengji
    MicroRNA-125b-5p mediates post-transcriptional regulation of hepatitis B virus replication via the LIN28B/let-7 axis
    In: RNA Biology Jg. 14 (2017) Nr. 10, S. 1389 - 1398
    ISSN: 1547-6286; 1555-8584
  • Chen, Xueyuan; Zhou, Li; Peng, Nanfang; Yu, Haisheng; Li, Mengqi; Cao, Zhongying; Lin, Yong; Wang, Xueyu; Li, Qian; Wang, Jun; She, Yinglong; Zhu, Chengliang; Lu, Mengji; Zhu, Ying; Liu, Shi
    MicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction
    In: Journal of Biological Chemistry Jg. 292 (2017) Nr. 52, S. 21291 - 21303
    ISSN: 0021-9258; 1083-351X
  • Pett, Christian; Cai, Hui; Liu, Jia; Palitzsch, Björn; Schorlemer, Manuel; Hartmann, Sebastian; Stergiou, Natascha; Lu, Mengji; Kunz, Horst; Schmitt, Edgar; Westerlind, Ulrika
    Microarray analysis of antibodies induced with synthetic antitumor vaccines : specificity against diverse mucin core structures
    In: Chemistry - A European Journal Jg. 23 (2017) Nr. 16, S. 3875 - 3884
    ISSN: 0947-6539; 1521-3765
  • Liu, Yanan; Wang, Junzhong; Wang, Lu; Wang, Baoju; Yang, Shangqing; Wang, Qin; Luo, Jinzhuo; Feng, Xuemei; Yang, Xuecheng; Lu, Yinping; Roggendorf, Michael; Lu, Mengji; Yang, Dongliang; Liu, Jia
    Molecular cloning, characterization and expression analysis of Tim-3 and Galectin-9 in the woodchuck model
    In: Molecular Immunology Jg. 83 (2017) S. 127 - 136
    ISSN: 1872-9142; 0161-5890
  • Wu, Weimin; Liu, Yan; Lin, Yong; Pan, Danzhen; Yang, Dongliang; Lu, Mengji; Xu, Yang
    PreC and C Regions of Woodchuck Hepatitis Virus Facilitate Persistent Expression of Surface Antigen of Chimeric WHV-HBV Virus in the Hydrodynamic Injection BALB/c Mouse Model
    In: Viruses Jg. 9 (2017) Nr. 2, S. 35
    ISSN: 1999-4915
  • Meng, Zhongji; Lu, Mengji
    RNA Interference-Induced Innate Immunity, Off-Target Effect, or Immune Adjuvant?
    In: Frontiers in Immunology Jg. 8 (2017) S. 331
    ISSN: 1664-3224
  • Su, Xi; Liu, Shuhui; Zhang, Xianwen; Lam, Sin Man; Hu, Xue; Zhou, Yuan; Chen, Jizheng; Wang, Yun; Wu, Chunchen; Shui, Guanghou; Lu, Mengji; Pei, Rongjuan; Chen, Xinwen
    Requirement of cytosolic phospholipase A2 gamma in lipid droplet formation
    In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Jg. 1862 (2017) Nr. 7, S. 692 - 705
    ISSN: 1879-2618; 1388-1981
  • Xu, Chunli; Lu, Yinping; Zheng, Xin; Feng, Xuemei; Yang, Xuecheng; Timm, Jörg; Wu, Jun; Wang, Baoju; Lu, Mengji; Yang, Dongliang; Liu, Jia
    TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure
    In: Frontiers in Immunology Jg. 8 (2017) S. 1609
    ISSN: 1664-3224
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    ISSN: 1600-0641
  • Lu, Mengji; Wang, B.; Pan, D.; Wu, W.; Xu, Y.; Yang, D.; Lin, Y.
    Persistence of chimeric Hepatitis B viruses in the hydrodynamic injection mouse model
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S165
    ISSN: 1600-0641
  • Qin, Bo; Pei, RongJuan; He, TingTing; Huang, ZhaoHui; Pan, GuoShao; Tu, ChunYu; Lu, Mengji; Chen, XinWen
    Polymerase mutations rtN238R, rtT240Y and rtN248H of hepatitis B virus decrease susceptibility to adefovir
    In: Chinese Science Bulletin Jg. 58 (2013) Nr. 15, S. 1760 - 1766
    ISSN: 1861-9541; 1001-6538; 0250-7862
  • Fiedler, Melanie; Kosinska, Anna; Schumann, Alexandra; Brovko, Olena; Walker, Andreas; Lu, Mengji; Johrden, Lena; Mayer, Anja; Wildner, Oliver; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus
    In: Journal of Virology Jg. 87 (2013) Nr. 13, S. 7708 - 7716
    ISSN: 1098-5514; 1098-5514
  • Meng, Zhongji; Zhang, Xiaoyong; Wu, Jun; Pei, Rongjuan; Xu, Yang; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji
    RNAi induces innate immunity through multiple cellular signaling pathways
    In: PLoS One Jg. 8 (2013) Nr. 5,
    ISSN: 1932-6203
  • Huang, S.; Wang, J.; Song, Z.; Yang, D.; Zhu, Z.; Feng, X.; Lu, Mengji; Zhu, B.; Wang, B.
    Rapamycin modulates the course of Hepatitis B Virus (HBV) infection in hydrodynamic injection mouse model : the role of Treg in HBV persistence
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S156 - S157
    ISSN: 1600-0641
  • Lu, Mengji; Zhang, X.; Deng, W.; Li, B.; Hou, J.; Liu, H.
    Regulation of HBV replication bymicroRNA-449a through targeting creb5 in hepatoma cells
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S165
    ISSN: 1600-0641
  • Liu, Jia; Jiang, Min; Ma, Zhiyong; Dietze, Kirsten; Zelinskyy, Gennadiy; Yang, Dongliang; Dittmer, Ulf; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro
    In: The Journal of Immunology Jg. 191 (2013) Nr. 12, S. 6178 - 6190
    ISSN: 1550-6606
  • Qin, Bo; Budeus, Bettina; Cao, Liang; Wu, Chunchen; Wang, Yun; Zhang, Xiaoyong; Rayner, Simon; Hoffmann, Daniel; Lu, Mengji; Chen, Xinwen
    The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    In: Antiviral Research Jg. 97 (2013) Nr. 2, S. 93 - 100
    ISSN: 0166-3542; 1872-9096
  • Wu, Chunchen; Shi, Hui; Wang, Yun; Lu, Mengji; Xu, Yang; Chen, Xinwen
    A case of hepatitis B reactivation due to the hepatitis B virus escape mutant in a patient undergoing chemotherapy
    In: Virologica Sinica Jg. 27 (2012) Nr. 6, S. 369 - 372
    ISSN: 1674-0769; 1995-820X
  • Wu, Chunchen; Deng, Wanyu; Deng, Liu; Cao, Liang; Qin, Bo; Li, Songxia; Wang, Yun; Pei, Rongjuan; Yang, Dongliang; Lu, Mengji; Chen, Xinwen
    Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg) determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance
    In: Journal of Virology Jg. 86 (2012) Nr. 8, S. 4658 - 4669
    ISSN: 1098-5514; 0022-538X
  • Xu, Song; Pei, Rongjuan; Guo, Min; Han, Qingxia; Lai, Juan; Wang, Yun; Wu, Chunchen; Zhou, Yuan; Lu, Mengji; Chen, Xinwen
    Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly
    In: Journal of Virology Jg. 86 (2012) Nr. 23, S. 13025 - 13037
    ISSN: 0022-538X; 1098-5514
  • Kosinska, Anna D.; Johrden, Lena; Zhang, Ejuan; Fiedler, Melanie; Mayer, Anja; Wildner, Oliver; Lu, Mengji; Roggendorf, Michael
    DNA Prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model
    In: Journal of Virology Jg. 86 (2012) Nr. 17, S. 9297 - 9310
    ISSN: 0022-538X; 1098-5514
  • Sallam, T.A.; Raja'a, Y.A.; Bahaj, S.; Al-Shami, A.M.; Lu, Mengji; Roggendorf, Michael; Tong, C.Y.W.
    Hepatitis B virus carrier rate, prevalence and susceptibility and impact of immunization program among households in the city of Taiz, Yemen
    In: Vaccine Jg. 30 (2012) Nr. 37, S. 5564 - 5568
    ISSN: 0264-410X; 1873-2518
  • Zhu, Wenbo; Wu, Chunchen; Deng, Wanyu; Pei, Rongjun; Wang, Yun; Cao, Liang; Qin, Bo; Lu, Mengji; Chen, Xinwen
    Inhibition of the HCV Core Protein on the Immune Response to HBV Surface Antigen and on HBV Gene Expression and Replication In Vivo
    In: PLoS One Jg. 7 (2012) Nr. 9, S. e45146
    ISSN: 1932-6203
  • Fan, Hebin; Zhu, Zhenni; Wang, Yang; Zhang, Xiaoyong; Lu, Yinping; Tao, Yuanqing; Fan, Wei; Wang, Zhongdong; Wang, Hu; Roggendorf, Micheal; Lu, Mengji; Wang, Baoju; Yang, Dongliang
    Molecular characterization of the type I IFN receptor in two woodchuck species and detection of its expression in liver samples from woodchucks infected with woodchuck hepatitis virus (WHV)
    In: Cytokine Jg. 60 (2012) Nr. 1, S. 179 - 185
    ISSN: 1043-4666; 1096-0023
  • Jiang, Min; Liu, Jia; Zhang, Ejuan; Meng, Zhongji; Wang, Baoju; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Molecular characterization of woodchuck interleukin-10 receptor and enhanced function of specific T cells from chronically infected woodchucks following its blockade
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 35 (2012) Nr. 6, S. 563 - 573
    ISSN: 0147-9571; 1878-1667
  • Zhang, Xiaoyong; Kraft, Anke; Bröring, Ruth; Schlaak, Jörg Friedrich; Dittmer, Ulf; Lu, Mengji
    Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections
    In: Expert Opinion on Drug Discovery Jg. 7 (2012) Nr. 7, S. 597 - 611
    ISSN: 1746-045X; 1746-0441
  • Yang, Yinke; Wang, Baoju; Yang, Dongliang; Lu, Mengji; Xu, Yang
    Prokaryotic expression of woodchuck cytotoxic T lymphocyte antigen 4 (wCTLA-4) and preparation of polyclonal antibody to wCTLA-4
    In: Protein Expression and Purification Jg. 81 (2012) Nr. 2, S. 181 - 185
    ISSN: 1046-5928
  • Pei, Rongjuan; Zhang, Xiaoyong; Xu, Song; Meng, Zhongji; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen
    Regulation of Hepatitis C virus replication and gene expression by the MAPK-ERK pathway
    In: Virologica Sinica Jg. 27 (2012) Nr. 5, S. 278 - 285
    ISSN: 1674-0769; 1995-820X
  • Zhang, Xiaoyong; Ma, Zhiyong; Liu, Hongyan; Liu, Jia; Meng, Zhongji; Bröring, Ruth; Yang, Dongliang; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Role of Toll-like receptor 2 in the immune response against hepadnaviral infection
    In: Journal of Hepatology Jg. 57 (2012) Nr. 3, S. 522 - 528
    ISSN: 0168-8278; 1600-0641
  • Fang, Haoshu; Liu, Anding; Dirsch, Olaf; Sun, Jian; Jin, Hao; Lu, Mengji; Yang, Dongliang; Dahmen, Uta
    Serum LBP levels reflect the impaired synthetic capacity of the remnant liver after partial hepatectomy in rats
    In: Journal of Immunological Methods Jg. 382 (2012) Nr. 1-2, S. 68 - 75
    ISSN: 1872-7905; 0022-1759
  • Bröring, Ruth; Montag, Mario; Jiang, Min; Lu, Mengji; Sowa, Jan-Peter; Kleinehr, Kathrin; Gerken, Guido; Schlaak, Jörg Friedrich
    Corticosteroids shift the Toll-like receptor response pattern of primary-isolated murine liver cells from an inflammatory to an anti-inflammatory state
    In: International Immunology Jg. 23 (2011) Nr. 9, S. 537 - 544
    ISSN: 0953-8178; 1460-2377
  • Yin, Ying; Wu, Chunchen; Song, Jingjiao; Wang, Junzhong; Zhang, Ejuan; Liu, Hongyan; Yang, Dongliang; Chen, Xinwen; Lu, Mengji; Xu, Yang
    DNA Immunization with Fusion of CTLA-4 to Hepatitis B Virus (HBV) Core Protein Enhanced Th2 Type Responses and Cleared HBV with an Accelerated Kinetic
    In: PLoS One Jg. 6 (2011) Nr. 7, S. 0022524
    ISSN: 1932-6203
  • Zhang, Zhenhuan; Li, Lei; Zhao, Xiping; Glebe, Dieter; Bremer, Corinna M.; Zhang, Zheng Mao; Tian, Yong Jun; Wang, Bao Ju; Yang, Yinke; Gerlich, Wolfram Hubert; Roggendorf, Michael; Li, Xu; Lu, Mengji; Yang, Dong Liang
    Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance
    In: Journal of Viral Hepatitis Jg. 18 (2011) Nr. 6, S. 424 - 433
    ISSN: 1352-0504; 1365-2893
  • Wang, Bao-Ju; Tian, Yong-Jun; Meng, Zhong-Ji; Jiang, Min; Wei, Bo-Qing; Tao, Yuan-Qing; Fan, Wei; Li, An-Yi; Bao, Jun-Jie; Li, Xin-Yu; Zhang, Zheng-Mao; Wang, Zhong-Dong; Wang, Hu; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Establishing a new animal model for hepadnaviral infection : Susceptibility of Chinese Marmota-species to woodchuck hepatitis virus infection
    In: Journal of General Virology Jg. 92 (2011) Nr. 3, S. 681 - 691
    ISSN: 0022-1317; 1465-2099
  • Pei, Rongjuan; Chen, Honghe; Lu, Lu; Zhu, Wandi; Beckebaum, Susanne; Cicinnati, Vito; Lu, Mengji; Chen, Xinwen
    Hepatitis C virus infection induces the expression of amphiregulin, a factor related to the activation of cellular survival pathways and required for efficient viral assembly
    In: Journal of General Virology Jg. 92 (2011) Nr. 10, S. 2237 - 2248
    ISSN: 0022-1317; 1465-2099
  • Wang, Bao-Ju; Bao, Jun-Jie; Wang, Jun-Zhong; Wang, Yang; Jiang, Min; Xing, Ming-You; Zhang, Wan-Guang; Qi, Jun-Ying; Roggendorf, Michael; Lu, Mengji; Yang, Dong-Liang
    Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma
    In: World Journal of Gastroenterology Jg. 17 (2011) Nr. 28, S. 3322 - 3329
    ISSN: 1007-9327
  • Liu, Min; Hao, Youhua; Ding, Honghui; Yang, Dongliang; Lu, Mengji
    Interleukin-10 is expressed in HepG2.2.15 cells and regulated by STAT1 pathway
    In: Journal of Huazhong University of Science and Technology Jg. 31 (2011) Nr. 5, S. 625 - 631
    ISSN: 0257-716X
  • Zhang, Xiaoyong; Zhang, Ejuan; Ma, Zhiyong; Pei, Rongjuan; Jiang, Min; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1
    In: Hepatology Jg. 53 (2011) Nr. 5, S. 1476 - 1485
    ISSN: 0270-9139; 1527-3350
  • Bröring, Ruth; Lu, Mengji; Schlaak, Jörg Friedrich; Schlaak, Joerg F.
    Role of Toll-like receptors in liver health and disease
    In: Clinical Science Jg. 121 (2011) Nr. 10, S. 415 - 426
    ISSN: 1470-8736; 0143-5221; 0301-0538; 0143-5221; 0009-9287
  • Xu, Yang; Köck, Josef; Lu, Yinping; Yang, Dongliang; Lu, Mengji; Zhao, Xiping
    Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri
    In: Comparative Immunology, Microbiology and Infectious Diseases Jg. 34 (2011) Nr. 4, S. 361 - 368
    ISSN: 1878-1667
  • Zhang, Ejuan; Zhang, Xiaoyong; Liu, Jia; Wang, Baoju; Tian, Yongjun; Kosinska, Anna D.; Ma, Zhiyong; Xu, Yang; Dittmer, Ulf; Roggendorf, Michael; Yang, Dongliang; Lu, Mengji
    The Expression of PD-1 Ligands and Their Involvement in Regulation of T Cell Functions in Acute and Chronic Woodchuck Hepatitis Virus Infection
    In: PLoS One Jg. 6 (2011) Nr. 10, S. 0026196
    ISSN: 1932-6203
  • Zelinskyy, Gennadiy; Myers, Lara; Dietze, Kirsten; Gibbert, Kathrin; Roggendorf, Michael; Liu, Jia; Lu, Mengji; Kraft, Anke R.; Teichgräber, Volker; Hasenkrug, Kim J.; Dittmer, Ulf
    Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication
    In: The Journal of Immunology Jg. 187 (2011) Nr. 7, S. 3730 - 3737
    ISSN: 1550-6606; 0022-1767
  • Zhang, X.; Zhang, E.; Meng, Z.; Ma, Z.; Schlaak, Jörg Friedrich; Lu, Mengji
    110 Modulation of HBV replication and cellular gene expression by microrna-1
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S49 - S50
    ISSN: 0168-8278
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Wu, J.; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    627 HBV suppresses TLR signaling and the crosstalk to the adaptive immune system in murine and human cells
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S246
    ISSN: 0168-8278; 1600-0641
  • Liu, Jia; Hu, Bin; Yang, Yan; Ma, Zhiyong; Yu, Yuan; Liu, Shenpei; Wang, Baoju; Zhao, Xiping; Lu, Mengji; Yang, Dongliang
    A new splice variant of the major subunit of human asialoglycoprotein receptor encodes a secreted form in hepatocytes
    In: PLoS One Jg. 5 (2010) Nr. 9,
    ISSN: 1932-6203
  • Wu, Chunchen; Zhang, Xiaoyong; Tian, Zhang; Song, Jianhua; Yang, Dongliang; Roggendorf, Michael; Lu, Mengji; Chen, Xinwen; Tian, Y.
    Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
    In: Journal of General Virology Jg. 91 (2010) Nr. 2, S. 483 - 492
    ISSN: 1465-2099; 0022-1317
  • Liu, Jia; Yang, Yan; Hu, Bin; Ma, Zhi-Yong; Huang, Hong-Ping; Yu, Yuan; Liu, Shen-Pei; Lu, Mengji; Yang, Dong-Liang
    Development of HBsAg-binding aptamers that bind HepG2.2.15 cells via HBV surface antigen
    In: Virologica Sinica Jg. 25 (2010) Nr. 1, S. 27 - 35
    ISSN: 1995-820X
  • Hu, Bin; Yang, Yan; Liu, Jia; Ma, Zhiyong; Huang, Hongping; Liu, Shenpei; Yu, Yuan; Hao, Youhua; Wang, Baoju; Lu, Mengji; Yang, Dongliang
    Establishment of a functional cell line expressing both subunits of H1a and H2c of human hepatocyte surface molecule ASGPR
    In: Journal of Huazhong University of Science and Technology Jg. 30 (2010) Nr. 5, S. 556 - 561
    ISSN: 0257-716X; 1672-0733
  • Li, Yanmei; Chen, Jizheng; Wu, Chunchen; Wang, Linding; Lu, Mengji; Chen, Xinwen
    Hepatitis B virus/hepatitis C virus upregulate angiopoietin-2 expression through mitogen-activated protein kinase pathway
    In: Hepatology Research Jg. 40 (2010) Nr. 10, S. 1022 - 1033
    ISSN: 1872-034X; 1386-6346
  • Shen, Qingli; Cicinnati, Vito; Zhang, Xiaoyong; Iacob, Speranta; Weber, Frank; Sotiropoulos, Georgios; Radtke, Arnold; Lu, Mengji; Paul, Andreas; Gerken, Guido; Beckebaum, Susanne
    Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
    In: Molecular Cancer Jg. 9 (2010) S. 227
    ISSN: 1476-4598
  • Zhu, Wenbo; Chang, Yanzi; Wu, Chunchen; Han, Qingxia; Pei, Rongjuan; Lu, Mengji; Chen, Xinwen
    The Wild-Type Hepatitis C Virus Core Inhibits Initiation of Antigen-Specific T- and B-Cell Immune Responses in BALB/c Mice
    In: Clinical and Vaccine Immunology Jg. 17 (2010) Nr. 7, S. 1139 - 1147
    ISSN: 1556-6811; 1556-679X; 1098-6588; 1071-412X
  • Bröring, Ruth; Zhang, Xiaozhen; Kottilil, Shyam; Trippler, Martin; Jiang, Min; Lu, Mengji; Gerken, Guido; Schlaak, Jörg Friedrich
    The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response
    In: Gut Jg. 59 (2010) Nr. 8, S. 1111 - 1119
    ISSN: 1468-3288; 0017-5749
  • Roggendorf, Michael; Yang, D.; Lu, Mengji
    The woodchuck : A model for therapeutic vaccination against hepadnaviral infection
    In: Pathologie Biologie Jg. 58 (2010) Nr. 4, S. 308 - 314
    ISSN: 0369-8114; 1768-3114
  • Wu, Jun; Meng, Zhongji; Jiang, Min; Zhang, Ejuan; Trippler, Martin; Bröring, Ruth; Bucchi, Agnes; Krux, Frank; Dittmer, Ulf; Yang, Dongliang; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific
    In: Immunology Jg. 129 (2010) Nr. 3, S. 363 - 374
    ISSN: 1365-2567; 0019-2805
  • Lu, Mengji; Viazov, Sergey; Dittmer, Ulf; Roggendorf, Michael; aus dem Siepen, Marc
    Chronische Infektionen : ein Versagen des Immunsystems
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 34 - 47
    ISSN: 1869-3881
  • Lu, M.; Isogawa, M.; Hilken, Gero
    Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune response in mice and woodchucks.
    In: (J. Virol.) Jg. 79 (2005) Nr. 10, S. 6368 - 6376
  • Zeng, X.; Weinberger, K.M.; Gehrke, R.; Isogawa, M.; Hilken, Gero; Kemper, T.; Xu, Y.; Yang, D.; Jilg, W.; Roggendorf, M.; Lu, M.
    Mutant hepatitis B virus surface antigen (HbsAg) are immunogenic but may have a change specificity.
    In: Virology Jg. 329 (2004) S. 454 - 464
  • Lu, M.; Lohrengel, B.; Hilken, Gero; Kemper, T.; Roggendorf, M.
    Woodchuck gamma interferon upregulates major histocompartibility complex class I transcription but is unable to deplete woodchuck hepatitis virus replication intermediatesand RNAs in persistently infected woodchuck primary hepatocytes.
    In: (J. Virol.) Jg. 76 (2002) Nr. 1, S. 58 - 67
  • Haupt, K.; Siegel, F.; Lu, M.; Yang, D.; Hilken, Gero; Mann, K.; Roggendorf, M.; Saller, B.
    Induction of a cellular and humoral Immune response against preprocalcitonin by genetic immunization: A potential new treatment for medullary thyroid carcinoma.
    In: Endocrinology Jg. 142 (2001) Nr. 3, S. 1017 - 1023
  • Lu, M.; Hilken, Gero; Dongliang, Y.; Kemper, T.; Roggendorf, M.
    Replication of naturally occurring Woodchuck Hepatitis Virus: Deletion Mutants in primary hepatocytes cultures and after transmission to naive woodchucks.
    In: (J. Virology) Jg. 75 (2001) Nr. 8, S. 3811 - 3818
  • Lu, M.; Siegel, F.; Hilken, Gero; Kemper, T.; Roggendorf, M.
    DNA vaccination against hepadnavirus in the woodchuck model: priming immune response to woodchuck hepatitis virus core antigen protects against WHV infections.
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  • Haupt, K.; Siegel, F.; Lu, M.; Saller, B.; Hilken, Gero; Yang, D.; Mann, K.; Roggendorf, M.
    The GM-CSF gene enhances the immune response induced by DNA immunization against the tumor associated antigen calcitonin.
    In: (Arch. Dermatol. Res.) Jg. 294 (2000) Nr. 4, S. 216
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Kemper, T.; Schirmbeck, R.; Reimann, J.; Roggendorf, M.
    Immunization of woodchucks with plasmids expressing Woodchuck Hepatitis Virus (WHV) core antigen and surface antigen suppresses WHV infection.
    In: (J. Virology) Jg. 73 (1999) Nr. 1, S. 281 - 289
  • Abstracts

  • Zhang, X.; Ge, J.; Huang, Z.; Sun, J.; Lu, Mengji; Hou, J.
    Expression and Function of Toll-Like Receptor 7 in Chronic Hepatitis B Patients Links to Antiviral Effect of PEG-IFN-A-2A Therapy
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 / Jg. 64 (2016) Nr. 2, Suppl., S. S380 - S381
    ISSN: 0168-8278; 1600-0641
  • Liu, J.; Yang, D.; Lu, Mengji
    HBV Strengthens Intrahepatic Myeloid-Derived Cells Mediated T Cell Tolerance through TLR1/2 Induced Kupffer Cell Expansion and IL-10 Production
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 / Jg. 64 (2016) Nr. 2, Suppl., S. S515
    ISSN: 0168-8278; 1600-0641
  • Bröring, Ruth; Zhang, Z.; Trippler, M.; Real, C.; Werner, M.; Gerken, Guido; Schlaak, Jörg Friedrich; Lu, Mengji
    Hepatitis B virus activates toll-like receptor 2 signaling upon infection of primary human hepatocytes
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 / Jg. 64 (2016) Nr. 2, Suppl., S. S394
    ISSN: 0168-8278; 1600-0641
  • Liu, J.; Xu, C.; Zheng, X.; Lu, Mengji; Yang, D.
    Increased TLR2 Expression in Peripheral CD4+T Cells Promotes TH17 Cells Responses and is Associated with Disease Aggravation of HBV-Related Acute-on-Chronic Liver Failure
    In: Journal of Hepatology / International Liver Congress ; EASL ; Barcelona, April 13-17, 2016 / Jg. 64 (2016) Nr. 2, Suppl., S. S307
    ISSN: 0168-8278; 1600-0641
  • Zhang, X.; Liu, H.; Wang, B.; Ma, Z.; Zhang, J.; Yang, D.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Epigenetic control of Hepatitis B virus replication and farnesoid X receptor alpha expression by histone deacetylases 3
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Suppl. 2, S. S17
    ISSN: 0168-8278; 1600-0641
  • Liu, H.; Zhang, J.; Zhang, X.; Bleekmann, B.; Kemper, T.; Roggendorf, Michael; Dittmer, Ulf; Lu, Mengji
    Genomic analysis of the host response to hepatitis b virus infection
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Supplement 2, S. S187
    ISSN: 0168-8278; 1600-0641
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Poggenpohl, L.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Hepatitis B virus surface antigen suppresses innate and adaptive immune responses of murine and human liver cells
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Supplement 2, S. S174
    ISSN: 0168-8278; 1600-0641
  • Jiang, M.; Trippler, M.; Bröring, Ruth; Wu, J.; Zhang, E.; Zhang, X.; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    TLR-3 dependent immunological properties of liver cells are controlled by anti-inflammatory cytokines through modulation of MIR-155 expression
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Supplement 2, S. S302 - S303
    ISSN: 0168-8278; 1600-0641
  • Liu, J.; Jiang, M.; Ma, Z.; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    TLR1/2 ligand stimulated mouse liver endothelial cells produce IL-12 and trigger CD8+ T-Cell immunity
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Supplement 2, S. S311
    ISSN: 0168-8278; 1600-0641
  • Ma, Z.; Zhang, E.; Zhang, X.; Liu, J.; Lin, Y.; Wu, J.; Kosinska, A.; Dittmer, Ulf; Roggendorf, Michael; Yang, D.; Lu, Mengji
    TLR2 ligand PAM3CSK4 inhibits peptide-induced deletion of CD8 T cells to viral antigens in mouse model
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Supplement 2, S. S312
    ISSN: 0168-8278; 1600-0641
  • Wu, J.; Chen, M.; Xia, Y.; Sun, C.; Lin, Y.; Wang, J.; Guo, Y.; Wang, B.; Song, J.; Lu, Mengji; Yang, D.
    The clearance of Hepatitis B virus (HBV) n hydrodynamik injection mouse model by polyinosinic-polycytidylic acid (POLYIC) treatment is dependent on interferon-gamma
    In: Journal of Hepatology / International Liver Congress™ ; Annual meeting of the European Association for the Study of the Liver ; 18-22 April 2012, Barcelona / Jg. 56 (2012) Nr. Supplement 2, S. S319
    ISSN: 0168-8278; 1600-0641
  • Meng, Z.; Zhang, E.; Zhang, X.; Kosinska, A.; Xu, Y.; Yang, D.; Zhou, T.; Mason, W.; Roggendorf, Michael; Lu, Mengji
    DNA vaccination induces WHS/CAG specific T Cell immune responses in the newly constructed WHV transgenic mouse model
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 / Jg. 54 (2011) Nr. Suppl. 1, S. S441
    ISSN: 0168-8278; 1600-0641
  • Wang, J. Z.; Wang, B. J.; Huang, S. M.; Wu, J.; Zhu, Z. N.; Zhu, B.; Ding, H. H.; Feng, X. M.; Yin, Y.; Roggendorf, Michael; Lu, Mengji; Yang, D. L.
    Immunosuppression modulates the course of hepatitis B virus (HBV) infection in hydrodynamic injection mouse model
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 / Jg. 54 (2011) Nr. Suppl. 1, S. S127
    ISSN: 0168-8278; 1600-0641
  • Zhang, X.; Ma, Z.; Wu, C.; Zhang, E.; Bröring, Ruth; Schlaak, Jörg Friedrich; Roggendorf, Michael; Lu, Mengji
    Modulation of HBV replication by cell cycle and differentiation related micrornas
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 / Jg. 54 (2011) Nr. Suppl. 1, S. S448 - S449
    ISSN: 0168-8278; 1600-0641
  • Fiedler, Melanie; Schumann, A.; Kosinska, A.; Lu, Mengji; Johrden, L.; Wildner, O.; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects woodchucks from hepatitis D virus infection
    In: Journal of Hepatology / The International Liver Congress™ 2011 ; 46th annual meeting of the European Association for the Study of the Liver ; Berlin, 30 March-3 April 2011 / Jg. 54 (2011) Nr. Suppl. 1, S. S439
    ISSN: 0168-8278; 1600-0641
  • Jiang, M.; Wu, J.; Zhang, E.; Meng, Z.; Trippler, M.; Bröring, Ruth; Roggendorf, Michael; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    446 HCV/TLR3- dependent innate and adaptive immune functions of non-parenchymal liver cells are controlled by interleukin-10 and transforming growth factor beta
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S180
    ISSN: 0168-8278; 1600-0641
  • Zhang, E.; Kosinska, A.; Zhang, X.; Meng, Z.; Xu, Y.; Yang, D.; Roggendorf, Michael; Lu, Mengji;
    637 Enhanced TH2 type immune response in DNA immunization by fusion of WCTLA-4 to woodchuck hepatitis core antigen
    International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver,
    In: Journal of Hepatology Jg. 52 (2010) Nr. Suppl. 1, S. S249
    ISSN: 0168-8278; 1600-0641
  • Roggendorf, Michael; Ke, X.Y.; Yang, Y.; Yang, D.L.; Zhang, X.Y.; Meng, Z.J.; Kemper, T.; Wang, Q.J.; Lu, Mengji; Lu, L.;
    OL-022 The effect of double-stranded DNA on replication of hepatitis B virus and cellular signalling
    Fourth Ditan International Conference on Infectious Diseases - Changing Face of Infectious Diseases. 15-18 July 2010, Beijing,
    In: International Journal of Infectious Diseases Jg. 14 (2010) Nr. Suppl. 2, S. S10
    ISSN: 1878-3511; 1201-9712
  • Beiträge in Sammelwerken und Tagungsbänden

  • Liu, Jia; Huang, Xuan; Werner, Melanie; Bröring, Ruth; Yang, Dongliang; Lu, Mengji
    Advanced Method for Isolation of Mouse Hepatocytes, Liver Sinusoidal Endothelial Cells, and Kupffer Cells
    In: Hepatitis B Virus: Methods and Protocols / Guo, Haitao; Cuconati, Andrea (Hrsg.), 2017, S. 249 - 258
    ISBN: 978-1-4939-6700-1
  • Bauer, Dirk; Wasmuth, Susanne; Lu, Mengji; Heiligenhaus, Arnd
    Particle-mediated administration of plasmid DNA on corneas of BALB/c mice
    In: Biolistic DNA Delivery: Methods and Protocols / Sudowe, Stephan; Reske-Kunz, Angelika B. (Hrsg.), 2013, S. 215 - 220
    ISBN: 978-1-62703-109-7; 978-1-62703-110-3 ISSN: 1940-6029
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, M.
    Protektion von Woodchucks gegen Woodchuckhepatitisvirus (WHV)-Infektion durch DNA-Immunisierung mit WHcAg- und WHsAg-exprimierenden Plasmiden.
    In: Jahrestagung Gesellschaft für Virologie, Regensburg 2.-5. März 1998, 1998, S. 30
  • Lu, M.; Hilken, Gero; Kruppenbacher, J.; Reimann, J.; Roggendorf, M.
    Immunization of woodchucks with plasmids expressing Woodchuck Hepatitis Virus (WHV) core antigen and surface antigen confers protection from infection with WHV.
    In: Molecular Biology of Hepatitis B Viruses, Institut Pasteur, Paris. 21.-25.9.1997. 1997
  • Vorträge

  • Lu, Mengji; Hilken, Gero; Yang, D.; Roggendorf, Michael;
    Replikation von Deletionsmutanten des Woodchuck Hepatitis Virus (WHV) in primären Woodchuck Hepatitis Kulturen und in vivo nach einer Übertragung
    38. Tagung der GV-SOLAS, September 2000, Essen,
    (2000)