Personensuche
Personensuche
Es wurde 1 Person gefunden.
Institut für Pharmakogenetik am Universitätsklinikum Essen
Funktionen
-
Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Pharmakogenetik
Aktuelle Veranstaltungen
Keine aktuellen Veranstaltungen.
Vergangene Veranstaltungen (max. 10)
Keine vergangenen Veranstaltungen.
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
Association of the dopamine D2 receptor gene SNP rs1800497 with postoperative nausea and vomiting : A prospective cohort studyIn: European Journal of Anaesthesiology and Intensive Care (EJAIC), Jg. 3, 2024, Nr. 4, e0056DOI, Online Volltext (Open Access)
-
Patients’ and physicians’ awareness of clinical symptoms and disease severity in tuberous sclerosis complexIn: Orphanet Journal of Rare Diseases, Jg. 19, 2024, Nr. 1, 106DOI (Open Access)
-
Characterization of the promoter of the human farnesyltransferase beta subunit and the impact of the transcription factor OCT-1 on its expressionIn: Genomics, Jg. 114, 2022, Nr. 2, 110314DOI (Open Access)
-
FNTB Promoter Polymorphisms Are Independent Predictors of Survival in Patients with Triple Negative Breast CancerIn: Cancers, Jg. 14, 2022, Nr. 3, 468DOI (Open Access)
-
Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors : Results of the Heinz Nixdorf Recall StudyIn: Naunyn-Schmiedeberg's Archives of Pharmacology, Jg. 394, 2021, Nr. 8, S. 1713 – 1725DOI (Open Access)
-
Thrombospondin‐2 and ldh are putative predictive biomarkers for treatment with everolimus in second‐line metastatic clear cell renal cell carcinoma (Marc‐2 study)In: Cancers, Jg. 13, 2021, Nr. 11, 2594DOI (Open Access)
-
Genetic contribution to PONV riskIn: Anaesthesia Critical Care & Pain Medicine, Jg. 39, 2020, Nr. 1, S. 45 – 51
-
Genetic risk scores for coronary artery disease and its traditional risk factors : Their role in the progression of coronary artery calcification ; Results of the Heinz Nixdorf Recall studyIn: PLoS ONE, Jg. 15, 2020, Nr. 5, S. e0232735DOI, Online Volltext (Open Access)
-
Association of caspase 8 polymorphisms -652 6N InsDel and Asp302His with progression-free survival and tumor infiltrating lymphocytes in early breast cancerIn: Scientific Reports, Jg. 9, 2019, Nr. 1, S. 12594DOI (Open Access)
-
SNPs Within the MTOR Gene Are Associated With an Increased Risk of Developing De Novo Diabetes Mellitus Following the Administration of Everolimus in Liver Transplant RecipientsIn: Transplantation Proceedings, Jg. 51, 2019, Nr. 6, S. 1962 – 1971
-
Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitroIn: Skin Pharmacology and Physiology, Jg. 32, 2019, Nr. 3, S. 162 – 172
-
The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell linesIn: BMC Cancer, Jg. 19, 2019, S. 243DOI (Open Access)
-
Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative PlasticisersIn: International Journal of Molecular Sciences (IJMS), Jg. 19, 2018, Nr. 4, S. 1133DOI (Open Access)
-
CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effectiveIn: British Journal of Anaesthesia (BJA), Jg. 121, 2018, Nr. 1, S. 58 – 65DOI (Open Access)
-
No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip ArthroplastyIn: BioMed Research International, 2018, 3687415DOI, Online Volltext (Open Access)
-
A single intraperitoneal injection of bovine fetuin-A attenuates bone resorption in a murine calvarial model of particle-induced osteolysisIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS), Jg. 105, 2017, S. 262 – 268
-
Exploring the putative self-binding property of the human farnesyltransferase alpha-subunitIn: FEBS Letters, Jg. 591, 2017, Nr. 21, S. 3637 – 3648
-
Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS).In: International Journal of Molecular Sciences (IJMS), Jg. 18, 2017, Nr. 6DOI, Online Volltext (Open Access)
-
Impact of BCL2 polymorphisms on survival in transitional cell carcinoma of the bladderIn: Journal of Cancer Research and Clinical Oncology, Jg. 143, 2017, Nr. 9, S. 1659 – 1670
-
Pharmacogenetic association of blood-lipid related genetic variants with 5-year progression of coronary artery calcification following the treatment with statin in the Heinz Nixdorf Recall studyIn: Atherosclerosis, Jg. 263, 2017, S. e278
-
Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplastyIn: European Journal of Medical Research, Jg. 22, 2017, S. 29DOI (Open Access)
-
A Single Dose of the Anti-Resorptive Peptide Human Calcitonin Paradoxically Augments Particle- and Endotoxin-Mediated Pro-Inflammatory Cytokine Production In VitroIn: Hormone and Metabolic Research, Jg. 48, 2016, Nr. 9, S. 607 – 612
-
Association of a Common Oxytocin Receptor Gene Polymorphism with Self-Reported 'Empathic Concern' in a Large Population of Healthy VolunteersIn: PLoS ONE, Jg. 11, 2016, Nr. 7, S. e0160059DOI (Open Access)
-
Caspase-8 Polymorphisms As Independent Prongostic Factors For Survival In Breast Cancer PatientsIn: International Journal of Gynecological Cancer, Jg. 26, 2016, Nr. Suppl. 2, S. 30
-
Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis : a prospective observational trialIn: BMC Anesthesiology, Jg. 16, 2016, Nr. 1, S. 61DOI (Open Access)
-
Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancerIn: BMC Cancer, Jg. 16, 2016, S. 618DOI (Open Access)
-
Prognostische Relevanz von Caspase-8 Polymorphismen für das MammakarzinomIn: Geburtshilfe und Frauenheilkunde, Jg. 76, 2016, Nr. 5, A 30
-
The BCL2 -938C>A Promoter Polymorphism is Associated with Risk for and Time to Aseptic Loosening of Total Hip ArthroplastyIn: PLoS ONE, Jg. 11, 2016, Nr. 2, S. e0149528DOI, Online Volltext (Open Access)
-
AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinomaIn: The Journal of Laryngology and Otology, Jg. 129, 2015, Nr. 6, S. 580 – 586
-
Absence of telomerase reverse transcriptase promoter mutations in neuroblastomaIn: Biomedical Reports, Jg. 3, 2015, Nr. 4, S. 443 – 446
-
Calcitonin Gene-Related Peptide Modulates the Production of Pro-Inflammatory Cytokines Associated with Periprosthetic Osteolysis by THP-1 Macrophage-Like CellsIn: Neuroimmunomodulation, Jg. 22, 2015, Nr. 3, S. 152 – 165
-
Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imagingIn: Immunotherapy, Jg. 7, 2015, Nr. 317, S. 317ra199
-
The FNTB promoter polymorphism rs11623866 as a potential predictive biomarker for lonafarnib treatment of ovarian cancer patientsIn: British Journal of Clinical Pharmacology (BJCP), Jg. 80, 2015, Nr. 5, S. 1139 – 1148DOI (Open Access)
-
A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1In: Molecular Cancer, Jg. 13, 2014, 87DOI, Online Volltext (Open Access)
-
The FNTB-609G>C polymorphism as a possible predictive factor for efficacy of lonafarnib-treatment? : Exploratory analysis of a randomized phase II clinical trial in stage IIb-IV ovarian cancer, treated with first-line platinum-based chemotherapy with or without lonafarnibIn: Journal of Clinical Oncology (JCO), Jg. 32, 2014, Nr. 15 Suppl., S. e16534
-
Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patientsIn: Journal of Neuro-Oncology, Jg. 112, 2013, Nr. 2, S. 297 – 305
-
RANKL-associated suppression of particle-induced osteolysis in an aged model of Calcitonin and alpha-CGRP deficiency.In: Biomaterials, Jg. 34, 2013, Nr. 12, S. 2911 – 2919
-
Risk factors for thrombus formation on the amplatzer cardiac plug after left atrial appendage occlusionIn: JACC Cardiovascular Interventions, Jg. 6, 2013, Nr. 6, S. 606 – 613
-
The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemiaIn: BMC Cancer, Jg. 13, 2013, S. 452DOI (Open Access)
-
HCV-HIV-coinfected Patients of the Competence Network for HIV/AIDS Cohort : Impact of IL28B Polymorphisms on Sustained Virological ResponseIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG), Jg. 10, 2012, Nr. Suppl. 3, S. 36 – 37
-
The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell linesIn: Naunyn-Schmiedeberg's Archives of Pharmacology, Jg. 385, 2012, Nr. Suppl. 1, S. 7 – 7
-
Validation and Quantification of Osteoclasts as a Predictor of Polyethylene Particle Induced OsteolysisIn: Trends in Biomaterials & Artificial Organs, Jg. 26, 2012, Nr. 4, S. 161 – 166
-
Association of the CC genotype of the regulatory BCL2 promoter polymorphism (−938C>A) with better 2-year survival in patients with glioblastoma multiformeIn: Journal of Neurosurgery (JNS), Jg. 114, 2011, Nr. 6, S. 1631 – 1639
-
Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysisIn: BMC Musculoskeletal Disorders, Jg. 12, 2011, S. 186DOI, Online Volltext (Open Access)
-
High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary NeuroblastomaIn: Clinical Cancer Research, Jg. 17, 2011, Nr. 15, S. 5082 – 5092
-
Influence of the 393T>C Polymorphism of the GNAS1 Gene on the Intensity of Opiate WithdrawalIn: Pharmacopsychiatry, Jg. 44, 2011, Nr. 4, S. 159 – 160
-
Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinomaIn: International Journal of Cancer, Jg. 129, 2011, Nr. 10, S. 2390 – 2399
-
The prevalence of the c-kit exon 10 variant, M541L, in aggressive fibromatosis does not differ from the general populationIn: Journal of Clinical Pathology: JCP Online, Jg. 64, 2011, Nr. 11, S. 1021 – 1024
-
Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomasIn: Journal of Translational Medicine, Jg. 9, 2011, S. 139DOI (Open Access)
-
A rare case of propofol-induced acute liver failure and literature reviewIn: Case Reports in Gastroenterology, Jg. 4, 2010, Nr. 1, S. 57 – 65DOI (Open Access)
-
Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiformeIn: Journal of Cancer Research and Clinical Oncology, Jg. 136, 2010, Nr. 9, S. 1423 – 1429
-
Biochemical markers of particle induced osteolysis in C57BL/6 miceIn: Clinical Chemistry and Laboratory Medicine, Jg. 48, 2010, Nr. 11, S. 1641 – 1646
-
Gender‐dependent association of the GNAS1 T393C polymorphism with early aseptic loosening after total hip arthroplasty : Reply : Letters to the EditorsIn: Journal of Orthopaedic Research, Jg. 28, 2010, Nr. 9, S. 1258
-
The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levelsIn: European Journal of Haematology, Jg. 85, 2010, Nr. 2, S. 108 – 113
-
The XbaI G>T polymorphism of the glucose transporter 1 gene modulates ¹⁸F-FDG uptake and tumor aggressiveness in breast cancerIn: Journal of Nuclear Medicine (JNM), Jg. 51, 2010, Nr. 8, S. 1191 – 1197DOI (Open Access)
-
ALK Mutation Analysis in Patients of the German Neuroblastoma StudyIn: Klinische Pädiatrie, Jg. 221, 2009, Nr. 3, S. 195
-
DNA repair gene XRCC1 polymorphisms and outcome of renal cell carcinoma in Caucasian patientsIn: Anticancer Research, Jg. 29, 2009, Nr. 12, S. 5131 – 5135
-
The regulatory BCL2 promoter polymorphism (-938C>A) is associated with relapse and survival of patients with oropharyngeal squamous cell carcinomaIn: Annals of Oncology, Jg. 20, 2009, Nr. 6, S. 1094 – 1099DOI (Open Access)
-
The AA genotype of the regulatory BCL2 promoter polymorphism (-938C>A) is associated with a favorable outcome in lymph node negative invasive breast cancer patientsIn: Clinical Cancer Research, Jg. 13, 2007, Nr. 19, S. 5790 – 5797DOI (Open Access)
-
MTOR polymorphisms and de novo diabetes mellitus in liver transplantation patients treated with everolimus
87th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) ; 1 March – 3 March 2021, Digital,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 394, 2021, Nr. Suppl. 1, S. S25DOI (Open Access) -
Association of Caspase 8 polymorphisms with TILs and disease-free survival in primary breast cancer patientsIn: Journal of Clinical Oncology (JCO). Alexandria: American Society of Clinical Oncology (ASCO), Jg. 36, 2018, Nr. Suppl. 15, S. e24258DOI (Open Access)
-
Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit
84th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 20th Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) ; 26 February – 1 March 2018. Göttingen,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 391, 2018, Nr. 1, Supplement, S. S66 -
The BCL2-938C>A promoter polymorphism is associated with risk for and time to aseptic loosening of total hip arthroplasty
84th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 20th Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) ; 26 February – 1 March 2018, Göttingen,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 391, 2018, Nr. Suppl. 1, S73 Abstract P214 -
The prognostic impact of UDP-glucuronyltransferase 1A1*1 (UGT1A1*1) polymorphism in patients with advanced colorectal and non-colorectal cancer treated with irinotecan-based systemic chemotherapies
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment. Basel: Karger, Jg. 41, 2018, Nr. Suppl. 4, S. 122 – 123DOI (Open Access) -
Characterization of the promoter region of a variant of the beta-subunit of the human farnesyltransferase
Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V., 81th Annual Meeting, March 10 - 12, 2015, Kiel, Germany,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 388, 2015, Nr. Suppl. 1, S. 54 -
FNTB promoter polymorphisms influence survival in prostate cancer
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,In: Oncology Research and Treatment. Basel: Karger, Jg. 38, 2015, Nr. Suppl. 5, S. 80 -
The FNTB-609G > C polymorphism as a possible predictive factor for efficacy of lonafarnib-treatment? : Exploratory analysis of a randomized phase II clinical trial in stage IIb-IV ovarian cancer, treated with first-line platinum-based chemotherapy with or without lonafarnib
Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V., 81th Annual Meeting, March 10 - 12, 2015, Kiel, Germany,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 388, 2015, Nr. Suppl. 1, S. 52 -
High Expression of the alk Receptor Tyrosine Kinase Precedes Mutation as a Determining Factor of Unfavourable Phenotype in Primary Neuroblastoma
42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,In: Pediatric Blood and Cancer. Hoboken: Wiley-Blackwell - STM, Jg. 55, 2010, Nr. 5, S. 827 -
The T-allele of the GNB3 825C > T polymorphism is associated with increased intensity of opiate withdrawal
8th International Sphingolipid Club Meeting, Glasgow, UK, June 30 – July 2, 2010,In: Naunyn-Schmiedeberg's Archives of Pharmacology. Berlin: Springer, Jg. 381, 2010, Nr. Suppl. 1, S. 87 -
Genetische Variabilität des BCL2 Gens - Untersuchungen zum molekularen Mechanismus und der klinischen Bedeutung des BCL2 -938C>A PromotorpolymorphismusDuisburg, Essen, 2012
-
Bedeutung von Polymorphismen im Gen GNAS1Duisburg, Essen, 2007