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Fakultät Biologie - Molekularbiologie II
Anschrift
Universitätsstraße 5
45141 Essen
45141 Essen
Raum
S05 R04 H94
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E-Mail
Funktionen
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Professor/in, Molekularbiologie II
Aktuelle Veranstaltungen
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SoSe 2025
- Nano-Biophotonik (optional)
- Zell- und Molekularbiologie
- Methods in Cancer Research
- (Einführung in die) Molekularbiologie
- Übung Molekulare Zellbiologie für Molekularbiologen
- Praktikum Chemie für Lehramtsstudierende
- Molekularbiologie: Übungen zum Verständnis der Fachliteratur
- (Einführung in die) Molekularbiologie; Einführung in die molekulare Zellbiologie (LA Biologie)
- Anleitung zum wissenschaftlichen Arbeiten
Vergangene Veranstaltungen (max. 10)
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WiSe 2024
- Molekulare Zellbiologie
- Molekulare Onkologie
- Molecular Cell Biology
- Allgemeine Methoden in der Molekularbiologie
- Allgemeine Methoden (Bachelor Bio)
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Lehramtspraktikum (LA Ma)
- Zell- und Molekularbiologie
- Nano-Biophotonik (optional)
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Stepwise Modulation of Bridged Single-Benzene-Based Fluorophores for Materials ScienceIn: Chemistry - A European Journal 2025DOI (Open Access)
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Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1In: Chemistry - A European Journal , Jg. 30 2024, Nr. 56, e202401542DOI (Open Access)
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Merging of a Supramolecular Ligand with a Switchable Luminophore : Light-Responsiveness, Photophysics and BioimagingIn: Chemistry - A European Journal , Jg. 30 2024, Nr. 57, e202402578DOI (Open Access)
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Nanobodies : Effektive Immunwaffen gegen KrebsIn: Biospektrum , Jg. 30 2024, Nr. 7, S. 760 – 762DOI (Open Access)
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Old Passengers as New Drivers : Chromosomal Passenger Proteins Engage in Translesion SynthesisIn: Cells , Jg. 13 2024, Nr. 21, 1804DOI, Online Volltext (Open Access)
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Synergetic Enhancing Effects between Platinum Nanosensitizers and Clinically Approved Stabilizing Ligands in Proton Therapy, Causing High-Yield Double-Strand Breaks of Plasmid DNA at Relevant DoseIn: Advanced NanoBiomed Research , Jg. 4 2024, Nr. 11, 2400023DOI (Open Access)
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A Fluorophore-Labeled Lysine Dendrimer with an Oxo-Anion-Binding Motif for Tracking Gene TransfectionIn: ChemBioChem , Jg. 24 2023, Nr. 15, e202300296DOI (Open Access)
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Cationic Solution and Solid‐state Emitters : Robust Imaging Agents for Cells, Bacteria and ProtistsIn: Chemistry - A European Journal , Jg. 29 2023, Nr. 38, e202300334DOI (Open Access)
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Deoxyestrone-based lipofection agents with solution- and solid-state emission propertiesIn: Organic and Biomolecular Chemistry , Jg. 21 2023, S. 5762 – 5767DOI (Open Access)
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Exploiting Vitamin D Receptor and Its Ligands to Target Squamous Cell Carcinomas of the Head and NeckIn: International Journal of Molecular Sciences (IJMS) , Jg. 24 2023, Nr. 5, 4675DOI (Open Access)
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Impact of Peptide Sequences on Their Structure and Function : Mimicking of Virus-Like Nanoparticles for Nucleic Acid DeliveryIn: ChemBioChem , Jg. 24 2023, Nr. 1, e202200519DOI (Open Access)
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Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules , Jg. 24 2023, Nr. 8, S. 3666 – 3679
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Taspase1 facilitates Topoisomerase IIβ-mediated DNA double-strand breaks driving estrogen-induced transcriptionIn: Cells , Jg. 2023 2023, Nr. 12, 363DOI, Online Volltext (Open Access)
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The Apoptosis Inhibitor Protein Survivin Is a Critical Cytoprotective Resistor against Silica-Based NanotoxicityIn: Nanomaterials , Jg. 13 2023, Nr. 18, 2546DOI (Open Access)
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Tuning Nanobodies’ Bioactivity : Coupling to Ultrasmall Gold Nanoparticles Allows the Intracellular Interference with SurvivinIn: Small , Jg. 19 2023, Nr. 33, 2300871 , 10.1002/smll.202300871DOI (Open Access)
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A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin α InteractionIn: ChemMedChem , Jg. 17 2022, Nr. 1, e202100640DOI (Open Access)
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Advances towards Cell‐Specific Gene Transfection : A Small‐Molecule Approach Allows Order‐of‐Magnitude SelectivityIn: Chemistry - A European Journal , Jg. 28 2022, Nr. 43, e202202024DOI (Open Access)
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Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groupsIn: Beilstein Journal of Organic Chemistry , Jg. 18 2022, S. 1322 – 1331DOI (Open Access)
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances , Jg. 12 2022, Nr. 53, S. 34176 – 34184DOI (Open Access)
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GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubPIn: npj Biofilms and Microbiomes , Jg. 8 2022, Nr. 1, 35DOI (Open Access)
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Impact of Secretion-Active Osteoblast-Specific Factor 2 in Promoting Progression and Metastasis of Head and Neck CancerIn: Cancers , Jg. 14 2022, Nr. 9, 2337DOI (Open Access)
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Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules , Jg. 23 2022, Nr. 11, S. 4504 – 4518
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Selective Disruption of Survivin's Protein-Protein Interactions : A Supramolecular Approach Based on GuanidiniocarbonylpyrroleIn: ChemBioChem , Jg. 23 2022, Nr. 5, e202100618DOI (Open Access)
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The Taspase1/Myosin1f-axis regulates filopodia dynamicsIn: iScience , Jg. 25 2022, Nr. 6, 104355DOI, Online Volltext (Open Access)
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The Vitamin D Receptor–BIM Axis Overcomes Cisplatin Resistance in Head and Neck CancerIn: Cancers , Jg. 14 2022, Nr. 20, 5131DOI (Open Access)
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Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque loadIn: Acta Neuropathologica Communications , Jg. 9 2021, Nr. 1, S. 66DOI (Open Access)
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Luminescent Amphiphilic Aminoglycoside Probes to Study TransfectionIn: ChemBioChem , Jg. 22 2021, Nr. 9, S. 1563 – 1567DOI (Open Access)
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New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry , Jg. 125 2021, Nr. 1, S. 115 – 127DOI (Open Access)
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PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interactionIn: Chemical Communications: ChemComm , Jg. 57 2021, Nr. 25, S. 3091 – 3094DOI (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications , Jg. 12 2021, Nr. 1, S. 1505DOI, Online Volltext (Open Access)
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TNF-α-Inhibition Improves the Biocompatibility of Porous Polyethylene Implants In VivoIn: Tissue Engineering and Regenerative Medicine , Jg. 18 2021, Nr. 2, S. 297 – 303DOI (Open Access)
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Umbelliferone Decorated Water-soluble Zinc(II) Phthalocyanines : In Vitro Phototoxic Antimicrobial Anti-cancer AgentsIn: Chemistry - A European Journal , Jg. 27 2021, Nr. 59, S. 14672 – 14680DOI (Open Access)
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A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of ActionIn: Angewandte Chemie International Edition , Jg. 132 2020, Nr. 13, S. 5322 – 5325DOI (Open Access)
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Boosting nanotoxicity to combat multidrug-resistant bacteria in pathophysiological environmentsIn: Nanoscale Advances , Jg. 2 2020, Nr. 11, S. 5428 – 5440DOI (Open Access)
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Cancer-Cell-Specific Drug Delivery by a Tumor-Homing CPP-Gossypol Conjugate Employing a Tracelessly Cleavable LinkerIn: Chemistry - A European Journal , Jg. 26 2020, Nr. 14, S. 3010 – 3015DOI (Open Access)
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Erratum : Nanoparticle binding attenuates the pathobiology of gastric cancer-associated: Helicobacter pyloriIn: Nanoscale , Jg. 12 2020, Nr. 3, S. 2154 – 2155DOI (Open Access)
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Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition , Jg. 59 2020, Nr. 14, S. 5567 – 5571DOI (Open Access)
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Lipofection with estrone-based luminophores featuring aggregation-induced emission propertiesIn: RSC Advances , Jg. 10 2020, Nr. 33, S. 19643 – 19647DOI (Open Access)
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Mechanisms of nanotoxicity – biomolecule coronas protect pathological fungi against nanoparticle-based eradicationIn: Nanotoxicology , Jg. 14 2020, Nr. 9, S. 1157 – 1174
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Retraction of “Resistance to Nano-Based Antifungals Is Mediated by Biomolecule Coronas”In: ACS Applied Materials & Interfaces , Jg. 12 2020, Nr. 13, 15953
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Smart Glycopolymeric Nanoparticles for Multivalent Lectin Binding and Stimuli-Controlled Guest ReleaseIn: Biomacromolecules , Jg. 21 2020, Nr. 6, S. 2356 – 2364
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Supramolecular subphthalocyanine complexes-cellular uptake and phototoxicityIn: Chemical Communications: ChemComm , Jg. 56 2020, Nr. 55, S. 7653 – 7656
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The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale , Jg. 12 2020, Nr. 37, S. 19093 – 19103
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A Branched Tripeptide with an Anion-Binding Motif as a Novel Delivery Carrier for Efficient Gene TransfectionIn: ChemBioChem , Jg. 20 2019, Nr. 11, S. 1410 – 1416
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Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteinsIn: Organic and Biomolecular Chemistry , Jg. 17 2019, Nr. 17, S. 4359 – 4363
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Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing : Implications for the design of improved nanoantibioticsIn: Biomaterials , Jg. 192 2019, S. 551 – 559
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Is small smarter? Nanomaterial-based detection and elimination of circulating tumor cells : Current knowledge and perspectivesIn: International Journal of Nanomedicine , Jg. 14 2019, S. 4187 – 4209DOI (Open Access)
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Non-viral transfection vectors : Are hybrid materials the way forward?In: MedChemComm , Jg. 10 2019, Nr. 10, S. 1692 – 1718DOI (Open Access)
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Protein Dimerization Probed with Site-Specific Attached Single NanoparticlesIn: Biophysical Journal , Jg. 116 2019, Nr. 3, Suppl. 1, S. 284aDOI (Open Access)
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A dipeptide with enhanced anion binding affinity enables cell uptake and protein deliveryIn: Organic and Biomolecular Chemistry , Jg. 16 2018, Nr. 13, S. 2312 – 2317
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Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers.In: Scientific Reports , Jg. 8 2018, Nr. 1, S. 7326DOI (Open Access)
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Formation of Twisted β-Sheet Tapes from a Self-Complementary Peptide Based on Novel Pillararene-GCP Host–Guest Interaction with Gene Transfection PropertiesIn: Chemistry - A European Journal , Jg. 24 2018, Nr. 39, S. 9754 – 9759
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From Supramolecular Vesicles to Micelles : Controllable Construction of Tumor-Targeting Nanocarriers Based on Host–Guest Interaction between a Pillar[5]arene-Based Prodrug and a RGD-Sulfonate GuestIn: Small , Jg. 14 2018, Nr. 52, S. 1803952
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Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1In: The Journal of Biological Chemistry (JBC) , Jg. 293 2018, Nr. 25, S. 9724 – 9735DOI (Open Access)
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MTOR inhibitor-based combination therapies for pancreatic cancerIn: British Journal of Cancer (BJC) , Jg. 118 2018, S. 366 – 377DOI (Open Access)
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Nanomaterial-microbe cross-talk : physicochemical principles and (patho)biological consequencesIn: Chemical Society Reviews , Jg. 47 2018, Nr. 14, S. 5312 – 5337
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Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pyloriIn: Nanoscale , Jg. 10 2018, Nr. 3, S. 1453 – 1463
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Nanoparticle decoration impacts airborne fungal pathobiologyIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 115 2018, Nr. 27, S. 7087 – 7092DOI (Open Access)
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Nanosized food additives impact beneficial and pathogenic bacteria in the human gut : a simulated gastrointestinal studyIn: npj Science of Food , Jg. 2 2018, S. 22DOI (Open Access)
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On the influence of substitution patterns in thioether-based luminophores with aggregation-induced emission propertiesIn: ChemistrySelect , Jg. 3 2018, Nr. 4, S. 985 – 991
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Simultaneous Rayleigh/Mie and Raman/Fluorescence Characterization of Molecularly Functionalized Colloids by Correlative Single-Particle Real-Time Imaging in SuspensionIn: Analytical Chemistry , Jg. 90 2018, Nr. 1, S. 723 – 728
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Small Meets Smaller : Effects of Nanomaterials on Microbial Biology, Pathology, and EcologyIn: ACS Nano , Jg. 12 2018, Nr. 7, S. 6351 – 6359
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Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cellsIn: OncoTarget , Jg. 9 2018, Nr. 45, S. 27835 – 27850DOI (Open Access)
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TFIIA transcriptional activity is controlled by a 'cleave-And-run' Exportin-1/Taspase 1-switchIn: Journal of Molecular Cell Biology , Jg. 10 2018, Nr. 1, S. 33 – 47DOI (Open Access)
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A systematic structure–activity study of a new type of small peptidic transfection vector reveals the importance of a special oxo-anion-binding motif for gene deliveryIn: ChemBioChem , Jg. 18 2017, Nr. 22, S. 2268 – 2279
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Aromatic thioethers as novel luminophores with aggregation-induced fluorescence and phosphorescenceIn: Chemistry - A European Journal , Jg. 23 2017, Nr. 55, S. 13660 – 13668
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Efficient Gene Transfection through Inhibition of β-Sheet (Amyloid Fiber) Formation of a Short Amphiphilic Peptide by Gold NanoparticlesIn: Angewandte Chemie International Edition , Jg. 56 2017, Nr. 28, S. 8083 – 8088
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Morphology-Dependent Cell Imaging by Using a Self-Assembled Diacetylene Peptide AmphiphileIn: Angewandte Chemie International Edition , Jg. 56 2017, Nr. 46, S. 14526 – 14530
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Site-Specific SERS Assay for Survivin Protein Dimer : From Ensemble Experiments to Correlative Single-Particle ImagingIn: Small , Jg. 13 2017, Nr. 32, S. 1700802
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Survivin expression pattern in the intestine of normoxic and ischemic ratsIn: BMC Gastroenterology , Jg. 17 2017, S. 76DOI (Open Access)
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An Old Flame Never Dies : Survivin in Cancer and Cellular SenescenceIn: Gerontology , Jg. 62 2016, Nr. 2, S. 173 – 181
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Cleaving for growth : Threonine aspartase 1-a protease relevant for development and diseaseIn: The FASEB Journal , Jg. 30 2016, Nr. 3, S. 1012 – 1022
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Guanidiniocarbonyl pyrrole (GCP) conjugated PAMAM-G2, a highly efficient vector for gene delivery: The importance of DNA condensationIn: Chemical Communications: ChemComm , Jg. 52 2016, Nr. 84, S. 12446 – 12449
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Incorporation of a Non-Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene TransfectionIn: Angewandte Chemie International Edition , Jg. 55 2016, Nr. 2, S. 598 – 601
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Introduction of a tailor made anion receptor into the side chain of small peptides allows fine-tuning the thermodynamic signature of peptide-DNA bindingIn: Organic and Biomolecular Chemistry , Jg. 14 2016, Nr. 37, S. 8800 – 8803
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Membrane tethering of APP c-terminal fragments is a prerequisite for T668 phosphorylation preventing nuclear sphere generationIn: Cellular Signalling , Jg. 28 2016, Nr. 11, S. 1725 – 1734
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RHAMM splice variants confer radiosensitivity in human breast cancer cell linesIn: OncoTarget , Jg. 7 2016, Nr. 16, S. 21428 – 21440DOI (Open Access)
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Taspase1 : a 'misunderstood' protease with translational cancer relevanceIn: Oncogene , Jg. 35 2016, Nr. 26, S. 3351 – 3364
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A Tailor-Made Specific Anion-Binding Motif in the Side Chain Transforms a Tetrapeptide into an Efficient Vector for Gene DeliveryIn: Angewandte Chemie International Edition , Jg. 54 2015, Nr. 10, S. 2941 – 2944
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Evolutionary divergence of Threonine Aspartase1 leads to species-specific substrate recognitionIn: Biological Chemistry , Jg. 396 2015, Nr. 4, S. 367 – 376
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Fly versus man : Evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1In: The FASEB Journal , Jg. 29 2015, Nr. 5, S. 1973 – 1985
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No king without a crown – impact of the nanomaterial-protein corona on nanobiomedicineIn: Nanomedicine: Nanotechnology, Biology, and Medicine , Jg. 10 2015, Nr. 3, S. 503 – 519
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Sumoylation of HDAC2 promotes NF-κB-dependent gene expressionIn: OncoTarget , Jg. 6 2015, Nr. 9, S. 7123 – 7135DOI (Open Access)
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The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancersIn: Cytokine & Growth Factor Reviews , Jg. 26 2015, Nr. 4, S. 405 – 413
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The nanoparticle biomolecule corona : lessons learned – challenge accepted?In: Chemical Society Reviews , Jg. 44 2015, Nr. 17, S. 6094 – 6121DOI (Open Access)
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miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating SurvivinIn: International Journal of Cancer , Jg. 136 2015, Nr. 6, S. 1308 – 1320DOI (Open Access)
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Calcium phosphate increases the encapsulation efficiency of hydrophilic drugs (proteins, nucleic acids) into poly(D,L-lactide-co-glycolide acid) nanoparticles for intracellular deliveryIn: Journal of Materials Chemistry B: Materials for Biology and Medicine , Jg. 2 2014, Nr. 41, S. 7250 – 7259DOI (Open Access)
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Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem , Jg. 15 2014, Nr. 15, S. 2233 – 2237
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Quantitative profiling of the protein coronas that form around nanoparticlesIn: Nature Protocols , Jg. 9 2014, Nr. 9, S. 2030 – 2044
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Functional Characterization of Novel Mutations Affecting Survivin (BIRC5)-Mediated Therapy Resistance in Head and Neck Cancer PatientsIn: Human Mutation , Jg. 34 2013, Nr. 2, S. 395 – 404
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Rapid formation of plasma protein corona critically affects nanoparticle pathophysiologyIn: Nature Nanotechnology , Jg. 8 2013, Nr. 10, S. 772 – 781
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SIAH proteins : Critical roles in leukemogenesisIn: Leukemia , Jg. 27 2013, Nr. 4, S. 792 – 802
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Utilizing Combinatorial Chemistry and Rational Design : Peptidic Tweezers with Nanomolar Affinity to DNA Can Be Transformed into Efficient Vectors for Gene Delivery by Addition of a Lipophilic TailIn: Angewandte Chemie International Edition , Jg. 52 2013, Nr. 52, S. 14016 – 14020
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A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancerIn: OncoTarget , Jg. 3 2012, Nr. 1, S. 31 – 43DOI, Online Volltext (Open Access)
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Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivoIn: The FASEB Journal , Jg. 26 2012, Nr. 8, S. 3421 – 3429
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Chemico-genetic strategies to inhibit the leukemic potential of threonine aspartase-1In: Blood Cancer Journal , Jg. 2 2012, Nr. 6, S. e77DOI, Online Volltext (Open Access)
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Differential regulation of PML–RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1In: The International Journal of Biochemistry & Cell Biology , Jg. 44 2012, Nr. 1, S. 132 – 138
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Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasmIn: PLoS ONE , Jg. 7 2012, Nr. 1, S. e29559DOI, Online Volltext (Open Access)
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Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stressIn: Journal of Molecular Cell Biology , Jg. 4 2012, Nr. 5, S. 284 – 293DOI (Open Access)
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Efficient gene delivery into cells by a surprisingly small three-armed peptide ligandIn: Chemical Science , Jg. 3 2012, Nr. 4, S. 996 – 1002
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Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylationIn: Cellular Signalling , Jg. 24 2012, Nr. 7, S. 1453 – 1460
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Impact of the nanoparticle-protein corona on colloidal stability and protein structureIn: Langmuir , Jg. 28 2012, Nr. 25, S. 9673 – 9679
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Overexpression of the Catalytically Impaired Taspase1T234V or Taspase1D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia CellsIn: PLoS ONE , Jg. 7 2012, Nr. 5, S. e34142DOI, Online Volltext (Open Access)
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Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors.In: PLoS ONE , Jg. 6 2011, Nr. 5, S. e18253DOI (Open Access)
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Cell-based analysis of structure-function activity of threonine aspartase 1.In: The Journal of Biological Chemistry (JBC) , Jg. 286 2011, Nr. 4, S. 3007 – 3017
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Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona : a comprehensive quantitative proteomic analysisIn: ACS Nano , Jg. 5 2011, Nr. 9, S. 7155 – 7167
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The Importin-Alpha/Nucleophosmin Switch Controls Taspase1 Protease Function.In: Traffic: The International Journal of Intracellular Transport , Jg. 12 2011, Nr. 6, S. 703 – 714
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The heterodimerization domains of MLL-FYRN and FYRC-are potential target structures in t(4;11) leukemia.In: Leukemia , Jg. 25 2011, Nr. 4, S. 663 – 670
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An otoprotective role for the apoptosis inhibitor protein survivinIn: Cell Death and Disease , Jg. 1 2010, Nr. 51, e51DOI (Open Access)
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An update on the pathobiological relevance of nuclear receptors for cancers of the head and neckIn: Histology and Histopathology , Jg. 25 2010, Nr. 8, S. 1093 – 1104
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Cloning and functional characterization of the guinea pig apoptosis inhibitor protein SurvivinIn: Gene , Jg. 469 2010, Nr. 1-2, S. 9 – 17
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Expression analysis suggests a potential cytoprotective role of Birc5 in the inner earIn: Molecular and Cellular Neuroscience (MCN) , Jg. 45 2010, Nr. 3, S. 297 – 305
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Nuclear receptors in head and neck cancer: current knowledge and perspectives.In: International Journal of Cancer , Jg. 126 2010, Nr. 4, S. 801 – 809
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A phosphorylation-acetylation switch regulates STAT1 signaling.In: Genes & development : a journal of cellular and molecular biology , Jg. 23 2009, Nr. 2, S. 223 – 235
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Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivinIn: International Journal of Cancer , Jg. 124 2009, Nr. 9, S. 2033 – 2041
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Prognostic and therapeutic potential of nuclear receptors in head and neck squamous cell carcinomas.In: Journal of Oncology 2009, 349205
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Similar regulation of human inducible nitric oxide synthase (iNOS) expression by different isoforms of the RNA binding protein AUF1In: The Journal of Biological Chemistry (JBC) , Jg. 284 2009, Nr. 5, S. 2755 – 2766
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Translocation biosensors – cellular system integrators to dissect CRM1-dependent nuclear export by chemicogenomics.In: Sensors , Jg. 9 2009, Nr. 7, S. 5423 – 5445DOI (Open Access)
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Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis.In: Oncogene : an international journal , Jg. 27 2008, Nr. 6, S. 732 – 740
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NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomasIn: Cancer Research , Jg. 68 2008, Nr. 13, S. 5159 – 5166
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Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motilityIn: Oncogene , Jg. 27 2008, Nr. 13, S. 1853 – 1864
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Therapeutic potential of nuclear receptors.In: Expert Opinion on Therapeutic Patents , Jg. 18 2008, Nr. 8, S. 861 – 888
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Dynamic Intracellular Survivin as an Early Prognostic Marker in Oral Squamous Cell Carcinomas : Underlying Molecular Mechanism and PotentialIn: The Journal of Pathology , Jg. 211 2007, Nr. 5, S. 532 – 540
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Dynamic survivin in head and neck cancer: Molecular mechanism and therapeutic potentialIn: International Journal of Cancer , Jg. 121 2007, Nr. 6, S. 1169 – 1174
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Nuclear and Cytoplasmic Survivin: Molecular Mechanism, Prognostic, and Therapeutic Potential.In: Cancer Research , Jg. 67 2007, Nr. 13, S. 5999 – 6002
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Nuclear export is essential for the tumor-promoting activity of survivinIn: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 , Jg. 21 2007, Nr. 1, S. 207 – 216
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Survivin's Dual Role - An Export's View.In: Cell Cycle , Jg. 6 2007, Nr. 5, S. 518 – 521
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The Role of Survivin for Radiation Therapy : Prognostic and Predictive Factor and Therapeutic TargetIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics , Jg. 183 2007, Nr. 11, S. 593 – 599
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The differentiation antigen NY-BR-1 is a potential target for antibody based therapies in breast cancer.In: International Journal of Cancer , Jg. 120 2007, Nr. 12, S. 2635 – 2642
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The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex proteinIn: Cell Cycle , Jg. 6 2007, Nr. 12, S. 1502 – 1509
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Acetylation of Stat1 modulates NF-kB activityIn: Genes & development : a journal of cellular and molecular biology , Jg. 20 2006, Nr. 4, S. 473 – 485
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Nucleocytoplasmic shuttling and the biological activity of mouse survivin are regulated by an active nuclear export signalIn: Traffic: The International Journal of Intracellular Transport , Jg. 7 2006, Nr. 11, S. 1461 – 1472
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Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition.In: Cell death & differentiation : D & D ; cdd , Jg. 13 2006, Nr. 4, S. 576 – 585
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The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function.In: EMBO Reports , Jg. 7 2006, Nr. 12, S. 1259 – 1265
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Development of an autofluorescent translocation biosensor system to investigate protein-protein interactions in living cellsIn: Analytical Chemistry , Jg. 77 2005, Nr. 15, S. 4815 – 4820
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Nuclear Export Is Evolutionarily Conserved in CVC Paired-Like Homeobox Proteins and Influences Protein Stability, Transcriptional Activation, and Extracellular Secretion.In: Molecular and Cellular Biology (MCB) , Jg. 6 2005, Nr. 7, S. 594 – 606
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Translocation Biosensors to Study Signal-Specific Nucleo-Cytoplasmic Transport, Protease Activity and Protein–Protein InteractionsIn: Traffic: The International Journal of Intracellular Transport , Jg. 6 2005, Nr. 7, S. 594 – 606
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Corrigendum to “Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics”In: Biomaterials , Jg. 263 2020, S. 120371
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