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Prof. Dr. med. Karl S. Lang

Institut für Immunologie der Medizinischen Fakultät der Universität Duisburg-Essen

Anschrift
Hufelandstr. 55
45122 Essen
Telefon
0201 723-4273
Telefax
0201 723-5410
E-Mail
KarlSebastian.Lang@uk-essen.de
Webseite
http://www.uk-essen.de/immunologie/

Funktionen

  • Direktor/in, Institut für Immunologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Lu, Zhe; Stencel, Olivia; Liu, Wei; Vasileiou, Eleni; Xu, Haifeng C; Pandey, Piyush; Stachura, Paweł; Elwy, Abdelrahman; Tsombal, Anastassia; Mai, Ann-Sophie; Auer, Franziska; Morcos, Mina N F; Seidl, Maximilian; Koziel, Sarah; Bruch, Peter-Martin; Dietrich, Sascha; Elitzur, Sarah; Hartmann, Gunther; Lang, Karl S.; Janssen, Stefan; Fischer, Ute; Bhatia, Sanil; Lang, Philipp A; Borkhardt, Arndt; Hauer, Julia; Pandyra, Aleksandra A
    Immune training enhances anti-viral responses and improves outcomes in Pax5−/⁺ mice susceptible to chronic infection
    In: EMBO Molecular Medicine Jg. 17 (2025) Nr. 4, S. 696 - 721
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Haifeng C.; Pandey, Piyush; Ward, Harry; Gorzkiewicz, Michal; Abromavičiūte, Džiuljeta; Tinz, Constanze; Müller, Lisa; Meyer, Caroline; Pandyra, Aleksandra A.; Yavas, Aslihan; Borkhardt, Arndt; Esposito, Irene; Lang, Karl S.; Lang, Philipp A.
    High-Affinity–Mediated Viral Entry Triggers Innate Affinity Escape Resulting in Type I IFN Resistance and Impaired T Cell Immunity
    In: The Journal of Immunology (JI) Jg. 212 (2024) Nr. 9, S. 1457 - 1466
    Online Volltext: dx.doi.org/ (Open Access)
  • Droege, Freya; König, Jochem; Lang, Karl S.; Jablonska, Jadwiga; Pylaeva, Ekaterina; Huckenbeck, Carolin; Wrobeln, Anna; Duerig, Inga; Thangavelu, Kruthika; Lang, Stephan; Geisthoff, Urban
    Increased Risk for Infections and Allergic Disease in Hereditary Hemorrhagic Telangiectasia
    In: Journal of Clinical Medicine (JCM) Jg. 13 (2024) Nr. 13, 3752
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Angendohr, Carolin; Missing, Leah; Ehlting, Christian; Wolf, Stephanie D.; Lang, Karl S.; Vucur, Mihael; Luedde, Tom; Bode, Johannes G.
    Interleukin 1 β suppresses bile acid-induced BSEP expression via a CXCR2-dependent feedback mechanism
    In: PLoS ONE Jg. 19 (2024) Nr. 12, e0315243
    Online Volltext: dx.doi.org/ (Open Access)
  • Elwy, Abdelrahman; Abdelrahman, Hossam; Specht, Julia; Dhiman, Swati; Christ, Theresa Charlotte; Lang, Judith; Friebus-Kardash, Justa; Recher, Mike; Lang, Karl S.
    Natural IgG protects against early dissemination of vesicular stomatitis virus
    In: Journal of Autoimmunity Jg. 146 (2024) 103230
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Judith; Soddemann, Matthias; Edwards, Michael J.; Wilson, Gregory C.; Lang, Karl S.; Gulbins, Erich
    Sphingosine Prevents Rhinoviral Infections
    In: International Journal of Molecular Sciences (IJMS) Jg. 25 (2024) Nr. 5, 2486
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Friebus-Kardash, Justa; Kuang, Fei; Peitz, Tobias; Hamdan, Thamer A.; Eisenberger, Ute; Boss, Kristina; Kribben, Andreas; Lang, Karl S.; Jahn, Michael
    Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients
    In: Cells Jg. 12 (2023) Nr. 14, 1892
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Abberger, Hanna; Hose, Matthias; Ninnemann, Anne; Menne, Christopher; Eilbrecht, Mareike; Lang, Karl S.; Matuschewski, Kai; Geffers, Robert; Herz, Josephine; Buer, Jan; Westendorf, Astrid; Hansen, Wiebke
    Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infections
    In: PLoS Pathogens Jg. 19 (2023) Nr. 11, e1011837
    Online Volltext: dx.doi.org/ (Open Access)
  • Stachura, Paweł; Liu, Wei; Xu, Haifeng C.; Wlodarczyk, Agnès; Stencel, Olivia; Pandey, Piyush; Vogt, Melina; Bhatia, Sanil; Picard, Daniel; Remke, Marc; Lang, Karl S.; Häussinger, Dieter; Homey, Bernhard; Lang, Philipp A.; Borkhardt, Arndt; Pandyra, Aleksandra A.
    Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors
    In: Molecular Cancer Jg. 22 (2023) Nr. 1, 136
    Online Volltext: dx.doi.org/ (Open Access)
  • Friebus-Kardash, Justa; Christ, Theresa Charlotte; Dietlein, Nikolaus; Elwy, Abdelrahman; Abdelrahman, Hossam; Holnsteiner, Lisa; Hu, Zhongwen; Rodewald, Hans-Reimer; Lang, Karl S.
    Usp22 Deficiency Leads to Downregulation of PD-L1 and Pathological Activation of CD8⁺ T Cells and Causes Immunopathology in Response to Acute LCMV Infection
    In: Vaccines Jg. 11 (2023) Nr. 10, 1563
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Wei; Stachura, Paweł; Xu, Haifeng C.; Váraljai, Renáta; Shinde, Prashant; Ganesh, Nikkitha Umesh; Mack, Matthias; Van Lierop, Anke; Huang, Anfei; Sundaram, Balamurugan; Lang, Karl S.; Picard, Daniel; Fischer, Ute; Remke, Marc; Homey, Bernhard; Rösch, Alexander; Häussinger, Dieter; Lang, Philipp A.; Borkhardt, Arndt; Pandyra, Aleksandra A.; Stachura, Pawel; Umesh Ganesh, Nikkitha
    BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment
    In: Cancer Research Jg. 82 (2022) Nr. 2, S. 264 - 277
    Online Volltext: dx.doi.org/ (Open Access)
  • Kronberg, Raphael M.; Haeberle, Lena; Pfaus, Melanie; Xu, Haifeng C.; Krings, Karina S.; Schlensog, Martin; Rau, Tilman; Pandyra, Aleksandra A.; Lang, Karl S.; Esposito, Irene; Lang, Philipp A.
    Communicator-Driven Data Preprocessing Improves Deep Transfer Learning of Histopathological Prediction of Pancreatic Ductal Adenocarcinoma
    In: Cancers Jg. 14 (2022) Nr. 8, 1964
    Online Volltext: dx.doi.org/ (Open Access)
  • Pylaeva, Ekaterina; Korschunow, Georg; Spyra, Ilona; Bordbari, Sharareh; Siakaeva, Elena; Ozel, Irem; Domnich, Maksim; Squire, Anthony; Hasenberg, Anja; Thangavelu, Kruthika; Hussain, Timon; Goetz, Moritz; Lang, Karl S.; Gunzer, Matthias; Hansen, Wiebke; Buer, Jan; Bankfalvi, Agnes; Lang, Stephan; Jablonska, Jadwiga
    During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes
    In: Cell Reports Jg. 40 (2022) Nr. 7, 111171
    Online Volltext: dx.doi.org/ (Open Access)
  • Podschwadt, Philip; Malyshkina, Anna; Windmann, Sonja; Papadamakis, Athanasios; Kerkmann, Leonie; Lapuente, Dennis; Tenbusch, Matthias; Lu, Mengji; Schindler, Michael; Lang, Karl Sebastian; Hansen, Wiebke; Bayer, Wibke
    Immune suppression of vaccine-induced CD8⁺ T cell-responses by gamma retrovirus envelope is mediated by interleukin-10 producing CD4⁺ T cells
    In: Frontiers in Immunology Jg. 13 (2022) 934399
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Cheung, Phyllis F.; Yang, JiaJin; Fang, Rui; Borgers, Arianna; Krengel, Kirsten; Stoffel, Anne; Althoff, Kristina; Yip, Chi Wai; Siu, Elaine H. L.; Ng, Linda W. C.; Lang, Karl S.; Cham, Lamin B.; Engel, Daniel Robert; Soun, Camille; Cima, Igor; Scheffler, Björn; Striefler, Jana K.; Sinn, Marianne; Bahra, Marcus; Pelzer, Uwe; Oettle, Helmut; Markus, Peter; Smeets, Esther M. M.; Aarntzen, Erik H. J. G.; Savvatakis, Konstantinos; Liffers, Sven-Thorsten; Lueong, Smiths S.; Neander, Christian; Bazarna, Anna; Zhang, Xin; Paschen, Annette; Crawford, Howard C.; Chan, Anthony W. H.; Cheung, Siu Tim; Siveke, Jens
    Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression
    In: Nature Communications Jg. 13 (2022) Nr. 1, 156
    Online Volltext: dx.doi.org/ (Open Access)
  • Bordbari, Sharareh; Mörchen, Britta; Pylaeva, Ekaterina; Siakaeva, Elena; Spyra, Ilona; Domnich, Maksim; Droege, Freya; Kanaan, Oliver; Lang, Karl S.; Schadendorf, Dirk; Lang, Stephan; Helfrich, Iris; Jablonska, Jadwiga
    SIRT1‐mediated deacetylation of FOXO3a transcription factor supports pro‐angiogenic activity of interferon‐deficient tumor‐associated neutrophils
    In: International Journal of Cancer Jg. 150 (2022) Nr. 7, S. 1198 - 1211
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Haifeng C.; Huang, Jun; Pandyra, Aleksandra A.; Pandey, Piyush; Wang, Ruifeng; Zhang, Zeli; Zhuang, Yuan; Gertzen, Christoph G.W.; Münk, Carsten; Herebian, Diran; Borkhardt, Arndt; Recher, Mike; Gohlke, Holger; Esposito, Irene; Oberbarnscheidt, Martin; Häussinger, Dieter; Lang, Karl S.; Lang, Philipp A.
    Single MHC-I Expression Promotes Virus-Induced Liver Immunopathology
    In: Hepatology Communications Jg. 6 (2022) Nr. 7, S. 1620 - 1633
    Online Volltext: dx.doi.org/ (Open Access)
  • Günther, Anne; Hose, Matthias; Abberger, Hanna; Schumacher, Fabian; Veith, Ylva; Kleuser, Burkhard; Matuschewski, Kai; Lang, Karl Sebastian; Gulbins, Erich; Buer, Jan; Westendorf, Astrid M.; Hansen, Wiebke
    The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis
    In: eLife Jg. 11 (2022) e77975
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wiechmann, Anika; Wilde, Benjamin; Tyczynski, Bartosz; Amann, Kerstin; Abdulahad, Wayel H.; Kribben, Andreas; Lang, Karl S.; Witzke, Oliver; Dolff, Sebastian
    CD107a⁺ (LAMP-1) Cytotoxic CD8⁺ T-Cells in Lupus Nephritis Patients
    In: Frontiers in Medicine Jg. 8 (2021) 556776
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Paluschinski, Martha; Jin, Cheng Jun; Qvartskhava, Natalia; Görg, Boris; Wammers, Marianne; Lang, Judith; Lang, Karl S.; Poschmann, Gereon; Stühler, Kai; Häussinger, Dieter
    Characterization of the scavenger cell proteome in mouse and rat liver
    In: Biological Chemistry Jg. 402 (2021) Nr. 9, S. 1073 - 1085
    Online Volltext: dx.doi.org/ (Open Access)
  • Werner, Julia; Kronberg, Raphael M.; Stachura, Pawel; Ostermann, Philipp N.; Müller, Lisa; Schaal, Heiner; Bhatia, Sanil; Kather, Jakob N.; Borkhardt, Arndt; Pandyra, Aleksandra A.; Lang, Karl S.; Lang, Philipp A.
    Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2
    In: Viruses Jg. 13 (2021) Nr. 4, 610
    Online Volltext: dx.doi.org/ (Open Access)
  • Duhan, Vikas; Khairnar, Vishal; Kitanovski, Simo; Hamdan, Thamer A.; Klein, Andrés D.; Lang, Judith; Ali, Murtaza; Adomati, Tom; Bhat, Hilal; Friedrich, Sarah-Kim; Li, Fanghui; Krebs, Philippe; Futerman, Anthony H.; Addo, Marylyn M.; Hardt, Cornelia; Hoffmann, Daniel; Lang, Philipp A.; Lang, Karl S.
    Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells
    In: Frontiers in Immunology Jg. 11 (2021) 607889
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Cappello, Sabrina; Sung, Hsu-Min; Ickes, Christian; Gibhardt, Christine S.; Vultur, Adina; Bhat, Hilal; Hu, Zhongwen; Brafford, Patricia; Denger, Andreas; Stejerean-Todoran, Ioana; Köhn, Rixa-Mareike; Lorenz, Verena; Künzel, Nicolas; Salinas, Gabriela; Stanisz, Hedwig; Legler, Tobias; Rehling, Peter; Schön, Michael P.; Lang, Karl S.; Helms, Volkhard; Herlyn, Meenhard; Hoth, Markus; Kummerow, Carsten; Bogeski, Ivan
    Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies
    In: Cancer Research Jg. 81 (2021) Nr. 21, S. 5540 - 5554
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Friedrich, Sarah-Kim; Schmitz, Rosa; Bergerhausen, Michael; Lang, Judith; Duhan, Vikas; Hardt, Cornelia; Tenbusch, Matthias; Prinz, Marco; Asano, Kenichi; Bhat, Hilal; Hamdan, Thamer A.; Lang, Philipp Alexander; Lang, Karl Sebastian
    Replication of influenza a virus in secondary lymphatic tissue contributes to innate immune activation
    In: Pathogens Jg. 10 (2021) Nr. 5, 622
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xu, Haifeng C.; Wang, Ruifeng; Shinde, Prashant V.; Walotka, Lara; Huang, Anfei; Poschmann, Gereon; Huang, Jun; Liu, Wei; Stühler, Kai; Schaal, Heiner; Bergthaler, Andreas; Pandyra, Aleksandra A.; Hardt, Cornelia; Lang, Karl S.; Lang, Philipp A.
    Slow viral propagation during initial phase of infection leads to viral persistence in mice
    In: Communications Biology Jg. 4 (2021) Nr. 1, 508
    Online Volltext: dx.doi.org/ (Open Access)
  • Al-Salihi, Mazin; Bornikoel, Anna; Zhuang, Yuan; Stachura, Pawel; Scheller, Jürgen; Lang, Karl S.; Lang, Philipp A.
    The role of ADAM17 during liver damage
    In: Biological Chemistry Jg. 402 (2021) Nr. 9, S. 1115 - 1128
    Online Volltext: dx.doi.org/ (Open Access)
  • Nettelbeck, Dirk M.; Leber, Mathias F.; Altomonte, Jennifer; Angelova, Assia; Beil, Julia; Berchtold, Susanne; Delic, Maike; Eberle, Jürgen; Ehrhardt, Anja; Engeland, Christine E.; Fechner, Henry; Geletneky, Karsten; Goepfert, Katrin; Holm, Per Sonne; Kochanek, Stefan; Kreppel, Florian; Krutzke, Lea; Kühnel, Florian; Lang, Karl S.; Marchini, Antonio; Moehler, Markus; Mühlebach, Michael D.; Naumann, Ulrike; Nawroth, Roman; Nüesch, Jürg; Rommelaere, Jean; Lauer, Ulrich M.; Ungerechts, Guy
    Virotherapy in Germany : recent activities in virus engineering, preclinical development, and clinical studies
    In: Viruses Jg. 13 (2021) Nr. 8, 1420
    Online Volltext: dx.doi.org/ (Open Access)
  • Namineni, Sukumar; O'Connor, Tracy; Faure-Dupuy, Suzanne; Johansen, Pål; Riedl, Tobias; Liu, Kaijing; Xu, Haifeng; Singh, Indrabahadur; Shinde, Prashant; Li, Fanghui; Pandyra, Aleksandra; Sharma, Piyush; Ringelhan, Marc; Muschaweckh, Andreas; Borst, Katharina; Blank, Patrick; Lampl, Sandra; Neuhaus, Katharina; Durantel, David; Farhat, Rayan; Weber, Achim; Lenggenhager, Daniela; Kündig, Thomas M.; Staeheli, Peter; Protzer, Ulrike; Wohlleber, Dirk; Holzmann, Bernhard; Binder, Marco; Breuhahn, Kai; Assmus, Lisa Mareike; Nattermann, Jacob; Abdullah, Zeinab; Rolland, Maude; Dejardin, Emmanuel; Lang, Philipp A.; Lang, Karl S.; Karin, Michael; Lucifora, Julie; Kalinke, Ulrich; Knolle, Percy A.; Heikenwalder, Mathias
    A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control
    In: Journal of Hepatology Jg. 72 (2020) Nr. 5, S. 960 - 975
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Judith; Bohn, Patrick; Bhat, Hilal; Jastrow, Holger; Walkenfort, Bernd; Cansiz, Feyza; Fink, Julian; Bauer, Michael; Olszewski, Dominik; Ramos-Nascimento, Ana; Duhan, Vikas; Friedrich, Sarah-Kim; Becker-Flegler, Katrin; Krawczyk, Adalbert; Edwards, Michael J.; Burchert, Andreas; Huber, Magdalena; Friebus-Kardash, Justa; Göthert, Joachim Rudolf; Hardt, Cornelia; Probst, Hans Christian; Schumacher, Fabian; Köhrer, Karl; Kleuser, Burkhard; Babiychuk, Eduard B.; Sodeik, Beate; Seibel, Jürgen; Greber, Urs F.; Lang, Philipp A.; Gulbins, Erich; Lang, Karl S.
    Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
    In: Nature Communications Jg. 11 (2020) Nr. 1, S. 1338
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bhat, Hilal; Zaun, Gregor; Hamdan, Thamer A.; Lang, Judith; Adomati, Tom; Schmitz, Rosa; Friedrich, Sarah-Kim; Bergerhausen, Michael; Cham, Lamin B.; Li, Fanghui; Ali, Murtaza; Zhou, Fan; Khairnar, Vishal; Duhan, Vikas; Brandenburg, Tim; Machlah, Yara Maria; Schiller, Maximilian; Berry, Arshia; Xu, Haifeng; Vollmer, Jörg; Häussinger, Dieter; Thier, Beatrice; Pandyra, Aleksandra A.; Schadendorf, Dirk; Paschen, Annette; Schuler, Martin; Lang, Philipp A.; Lang, Karl S.
    Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression
    In: Frontiers in Immunology Jg. 11 (2020) S. 1849
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Cham, Lamin B.; Adomati, Tom; Li, Fanghui; Ali, Murtaza; Lang, Karl S.
    CD47 as a Potential Target to Therapy for Infectious Diseases
    In: Antibodies Jg. 9 (2020) Nr. 3, S. 44
    Online Volltext: dx.doi.org/ (Open Access)
  • Zöller, Julia; Ebel, Jana-Fabienne; Khairnar, Vishal; Schmitt, Verena; Klopfleisch, Robert; Meiners, Jana; Seiffart, Virginia; Hansen, Wiebke; Buer, Jan; Singer, Bernhard B.; Lang, Karl S.; Westendorf, Astrid
    CEACAM1 regulates CD8⁺ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis
    In: Gut Microbes Jg. 11 (2020) Nr. 6, S. 1790 - 1805
    Online Volltext: dx.doi.org/ (Open Access)
  • David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A.; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D.; Tenbusch, Matthias; Dietze, Kirsten; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S.; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid; Dittmer, Ulf; Zelinskyy, Gennadiy
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
    In: PLoS Pathogens Jg. 16 (2020) Nr. 3, e1008340
    Online Volltext: dx.doi.org/ (Open Access)
  • Adomati, Tom; Cham, Lamin B.; Hamdan, Thamer A.; Bhat, Hilal; Duhan, Vikas; Li, Fanghui; Ali, Murtaza; Lang, Elisabeth; Huang, Anfei; Naser, Eyad; Khairnar, Vishal; Friedrich, Sarah-Kim; Lang, Judith; Friebus-Kardash, Justa; Bergerhausen, Michael; Schiller, Maximilian; Machlah, Yara Maria; Lang, Florian; Häussinger, Dieter; Ferencik, Stanislav; Hardt, Cornelia; Lang, Philipp A.; Lang, Karl S.
    Dead Cells Induce Innate Anergy via Mertk after Acute Viral Infection
    In: Cell Reports Jg. 30 (2020) Nr. 11, S. 3671 - 3681.e5
    Online Volltext: dx.doi.org/ (Open Access)
  • Zhuang, Yuan; Xu, Haifeng C.; Shinde, Prashant V.; Warfsmann, Jens; Vasilevska, Jelena; Sundaram, Balamurugan; Behnke, Kristina; Huang, Jun; Hoell, Jessica I.; Borkhardt, Arndt; Pfeffer, Klaus; Taha, Mohamed S.; Herebian, Diran; Mayatepek, Ertan; Brenner, Dirk; Ahmadian, Mohammad Reza; Keitel, Verena; Wieczorek, Dagmar; Häussinger, Dieter; Pandyra, Aleksandra A.; Lang, Karl S.; Lang, Philipp A.
    Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury
    In: Gut Jg. 69 (2020) Nr. 1, S. 133 - 145
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Florian; Singh, Yogesh; Salker, Madhuri S.; Ma, Ke; Pandyra, Aleksandra A.; Lang, Philipp A.; Lang, Karl S.
    Glucose transport in lymphocytes
    In: Pflügers Archiv: European Journal of Physiology Jg. 472 (2020) Nr. 9, S. 1401 - 1406
    Online Volltext: dx.doi.org/
  • Cham, Lamin B.; Torrez Dulgeroff, Laughing Bear; Tal, Michal Caspi; Adomati, Tom; Li, Fanghui; Bhat, Hilal; Huang, Anfei; Lang, Philipp A.; Moreno, Mary E.; Rivera, Jose M.; Galkina, Sofiya A.; Kosikova, Galina; Stoddart, Cheryl A.; McCune, Joseph M.; Myers, Lara M.; Weissman, Irving L.; Lang, Karl S.; Hasenkrug, Kim J.
    Immunotherapeutic blockade of CD47 inhibitory signaling enhances innate and adaptive immune responses to viral infection
    In: Cell Reports Jg. 31 (2020) Nr. 2, S. 107494
    Online Volltext: dx.doi.org/ (Open Access)
  • Hamdan, Thamer A.; Bhat, Hilal; Cham, Lamin B.; Adomati, Tom; Lang, Judith; Li, Fanghui; Murtaza, Ali; Hardt, Cornelia; Lang, Philipp A.; Duhan, Vikas; Lang, Karl S.
    Map3k14 as a regulator of innate and adaptive immune response during acute viral infection
    In: Pathogens Jg. 9 (2020) Nr. 2, S. 96
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lang, Philipp A.; Crome, Sarah Q.; Xu, Haifeng C.; Lang, Karl S.; Chapatte, Laurence; Deenick, Elissa K.; Grusdat, Melanie; Pandyra, Aleksandra A.; Pozdeev, Vitaly I.; Wang, Ruifeng; Holderried, Tobias A. W.; Cantor, Harvey; Diefenbach, Andreas; Elford, Alisha R.; McIlwain, David R.; Recher, Mike; Häussinger, Dieter; Mak, Tak W.; Ohashi, Pamela S.
    NK Cells Regulate CD8⁺ T Cell Mediated Autoimmunity
    In: Frontiers in Cellular and Infection Microbiology Jg. 10 (2020) 36
    Online Volltext: dx.doi.org/ (Open Access)
  • Carpinteiro, Alexander; Edwards, Michael J.; Hoffmann, Markus; Kochs, Georg; Gripp, Barbara; Weigang, Sebastian; Adams, Constantin; Carpinteiro, Elisa; Gulbins, Anne; Keitsch, Simone; Sehl, Carolin; Soddemann, Matthias; Wilker, Barbara; Kamler, Markus; Bertsch, Thomas; Lang, Karl S.; Patel, Sameer; Wilson, Gregory C.; Walter, Silke; Hengel, Hartmut; Pöhlmann, Stefan; Lang, Philipp A.; Kornhuber, Johannes; Becker, Katrin; Ahmad, Syed A.; Fassbender, Klaus; Gulbins, Erich
    Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells
    In: Cell Reports Medicine Jg. 1 (2020) Nr. 8, 100142
    Online Volltext: dx.doi.org/ (Open Access)
  • Beyer, Marc; Abdullah, Zeinab; Chemnitz, Jens M.; Maisel, Daniela; Sander, Jil; Lehmann, Clara; Thabet, Yasser; Shinde, Prashant V.; Schmidleithner, Lisa; Köhne, Maren; Trebicka, Jonel; Schierwagen, Robert; Hofmann, Andrea; Popov, Alexey; Lang, Karl S.; Oxenius, Annette; Buch, Thorsten; Kurts, Christian; Heikenwalder, Mathias; Fätkenheuer, Gerd; Lang, Philipp A.; Hartmann, Pia; Knolle, Percy A.; Schultze, Joachim L.
    Publisher Correction: Tumor-necrosis factor impairs CD4⁺ T cell–mediated immunological control in chronic viral infection
    In: Nature Immunology Jg. 21 (2020) Nr. 9, S. 1135
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Wei; Stachura, Paweł; Xu, Haifeng C.; Umesh Ganesh, Nikkitha; Cox, Fiona; Wang, Ruifeng; Lang, Karl S.; Gopalakrishnan, Jay; Häussinger, Dieter; Homey, Bernhard; Lang, Philipp A.; Pandyra, Aleksandra A.
    Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications
    In: Journal of Experimental & Clinical Cancer Research Jg. 39 (2020) 38
    Online Volltext: dx.doi.org/ (Open Access)
  • Bojkova, Denisa; Westhaus, Sandra; Costa, Rui; Timmer, Lejla; Funkenberg, Nora; Korencak, Marek; Streeck, Hendrik; Vondran, Florian; Bröring, Ruth; Heinrichs, Stefan; Lang, Karl S.; Ciesek, Sandra
    Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes
    In: Cells Jg. 9 (2020) Nr. 4, 1003
    Online Volltext: dx.doi.org/ (Open Access)
  • Such, Lina; Zhao, Fang; Liu, Derek; Thier, Beatrice; Le-Trilling, Vu Thuy Khanh; Sucker, Antje; Coch, Christoph; Pieper, Natalia; Howe, Sebastian; Bhat, Hilal; Kalkavan, Halime; Ritter, Cathrin; Brinkhaus, Robin; Ugurel, Selma; Köster, Johannes; Seifert, Ulrike; Dittmer, Ulf; Schuler, Martin; Lang, Karl S.; Kufer, Thomas A.; Hartmann, Gunther; Becker, Jürgen; Horn, Susanne; Ferrone, Soldano; Liu, David; Van Allen, Eliezer M.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Paschen, Annette
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    In: The Journal of Clinical Investigation (JCI) Jg. 130 (2020) Nr. 8, S. 4266 - 4281
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  • Hamdan, Thamer A.; Lang, Philipp A.; Lang, Karl S.
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    In: Pathogens Jg. 9 (2020) Nr. 2, 140
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  • Tal, Michal Caspi; Dulgeroff, Laughing Bear Torrez; Myers, Lara; Cham, Lamin B.; Mayer-Barber, Katrin D.; Bohrer, Andrea C.; Castro, Ehydel; Yiu, Ying Ying; Angel, Cesar Lopez; Pham, Ed; Carmody, Aaron B.; Messer, Ronald J.; Gars, Eric; Kortmann, Jens; Markovic, Maxim; Hasenkrug, Michaela; Peterson, Karin E.; Winkler, Clayton W.; Woods, Tyson A.; Hansen, Paige; Galloway, Sarah; Wagh, Dhananjay; Fram, Benjamin J.; Nguyen, Thai; Corey, Daniel; Kalluru, Raja Sab; Banaei, Niaz; Rajadas, Jayakumar; Monack, Denise M.; Ahmed, Aijaz; Sahoo, Debashis; Davis, Mark M.; Glenn, Jeffrey S.; Adomati, Tom; Lang, Karl S.; Weissman, Irving L.; Hasenkrug, Kim J.
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  • Friedrich, Sarah-Kim; Schmitz, Rosa; Bergerhausen, Michael; Lang, Judith; Cham, Lamin B.; Duhan, Vikas; Häussinger, Dieter; Hardt, Cornelia; Addo, Marylyn; Prinz, Marco; Asano, Kenichi; Lang, Philipp Alexander; Lang, Karl S.
    Usp18 expression in CD169⁺ macrophages is important for strong immune response after vaccination with VSV-EBOV
    In: Vaccines Jg. 8 (2020) Nr. 1, S. 142
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  • Poetsch, Joseph H.; Dahlke, Christine; Zinser, Madeleine E.; Kasonta, Rahel; Lunemann, Sebastian; Rechtien, Anne; Ly, My L.; Stubbe, Hans C.; Krähling, Verena; Biedenkopf, Nadine; Eickmann, Markus; Fehling, Sarah K.; Olearo, Flaminia; Strecker, Thomas; Sharma, Piyush; Lang, Karl S.; Lohse, Ansgar W.; Schmiedel, Stefan; Becker, Stephan; Addo, Marylyn M.
    Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in Humans
    In: The Journal of Infectious Diseases (JID) Jg. 219 (2019) Nr. 4, S. 556 - 561
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  • Dickow, Julia; Francois, Sandra; Kaiserling, Rouven-Luca; Malyshkina, Anna; Drexler, Ingo; Westendorf, Astrid Maria; Lang, Karl Sebastian; Santiago, Mario L.; Dittmer, Ulf; Sutter, Kathrin
    Diverse immunomodulatory effects of individual IFNα subtypes on virus-specific CD8⁺ T cell responses
    In: Frontiers in Immunology Jg. 10 (2019) 2255
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  • Bhat, Hilal; Lang, Karl S.; Hardt, Cornelia; Lang, Judith
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    In: Neurosignals Jg. 27 (2019) Nr. S1, S. 44 - 53
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  • Friedrich, Sarah-Kim; Lang, Philipp A.; Friebus-Kardash, Justa; Duhan, Vikas; Bezgovsek, Judith; Lang, Karl S.
    Mechanisms of lymphatic system-specific viral replication and its potential role in autoimmune disease
    In: Clinical and Experimental Immunology Jg. 195 (2019) Nr. 1, S. 64 - 73
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  • Duhan, Vikas; Hamdan, Thamer A.; Xu, Haifeng C.; Shinde, Prashant; Bhat, Hilal; Li, Fanghui; Al-Matary, Yahya; Häussinger, Dieter; Bezgovsek, Judith; Friedrich, Sarah-Kim; Hardt, Cornelia; Lang, Philipp A.; Lang, Karl S.
    NK cell-intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infection
    In: PLoS Pathogens Jg. 15 (2019) Nr. 6, S. e1007797
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  • Huang, Anfei; Shinde, Prashant V.; Huang, Jun; Senff, Tina; Xu, Haifeng C.; Margotta, Cassandra; Häussinger, Dieter; Willnow, Thomas E.; Zhang, Jinping; Pandyra, Aleksandra A.; Timm, Jörg; Weggen, Sascha; Lang, Karl S.; Lang, Philipp A.
    Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells
    In: JCI Insight Jg. 4 (2019) Nr. 17, e129856
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  • Behnke, Kristina; Zhuang, Yuan; Xu, Haifeng C.; Sundaram, Balamurugan; Reich, Maria; Shinde, Prashant V.; Huang, Jun; Modares, Nastaran Fazel; Tumanov, Alexei V.; Polz, Robin; Scheller, Jürgen; Ware, Carl F.; Pfeffer, Klaus; Keitel, Verena; Häussinger, Dieter; Pandyra, Aleksandra A.; Lang, Karl S.; Lang, Philipp A.
    Reply [Letter to the Editor: Characterization of CD169+ Macrophages in Liver Regeneration: Tissue Distribution and Fate?]
    In: Hepatology Jg. 70 (2019) Nr. 3, S. 1074 - 1075
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  • Lang, Philipp A.; Lang, Karl S.
    Stand by me(mory) : Chronic infection diminishes memory pool via IL-6/STAT1
    In: Journal of Experimental Medicine (JEM) Jg. 216 (2019) Nr. 3, S. 474 - 475
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  • Friebus-Kardash, Justa; Trendelenburg, Marten; Eisenberger, Ute; Ribi, Camillo; Chizzolini, Carlo; Huynh-Do, Uyen; Lang, Karl S.; Wilde, Benjamin; Kribben, Andreas; Witzke, Oliver; Dolff, Sebastian; Hardt, Cornelia
    Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis
    In: BMC Nephrology Jg. 20 (2019) 430
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  • Solmaz, Gülhas; Puttur, Franz; Francozo, Marcela; Lindenberg, Marc; Guderian, Melanie; Swallow, Maxine; Duhan, Vikas; Khairnar, Vishal; Kalinke, Ulrich; Ludewig, Burkhard; Clausen, Björn E.; Wagner, Hermann; Lang, Karl S.; Sparwasser, Tim D.
    TLR7 Controls VSV Replication in CD169+ SCS Macrophages and Associated Viral Neuroinvasion
    In: Frontiers in Immunology Jg. 10 (2019) S. 466
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  • Cham, Lamin B.; Friedrich, Sarah-Kim; Adomati, Tom; Bhat, Hilal; Schiller, Maximilian; Bergerhausen, Michael; Hamdan, Thamer; Li, Fanghui; Machlah, Yara Maria; Ali, Murtaza; Duhan, Vikas; Lang, Karl S.; Friebus-Kardash, Justa; Lang, Judith
    Tamoxifen protects from vesicular stomatitis virus infection
    In: Pharmaceuticals Jg. 12 (2019) Nr. 4, 142
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  • Li, Kai; Neumann, Konstantin; Duhan, Vikas; Namineni, Sukumar; Hansen, Anne Louise; Wartewig, Tim; Kurgyis, Zsuzsanna; Holm, Christian K.; Heikenwalder, Mathias; Lang, Karl S.; Ruland, Jürgen
    The uric acid crystal receptor Clec12A potentiates type I interferon responses
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 116 (2019) Nr. 37, S. 18544 - 18549
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  • Sundaram, Balamurugan; Behnke, Kristina; Belancic, Andrea; Al-Salihi, Mazin A.; Thabet, Yasser; Polz, Robin; Pellegrino, Rossella; Zhuang, Yuan; Shinde, Prashant V.; Xu, Haifeng C.; Vasilevska, Jelena; Longerich, Thomas; Herebian, Diran; Mayatepek, Ertan; Bock, Hans H.; May, Petra; Kordes, Claus; Aghaeepour, Nima; Mak, Tak W.; Keitel, Verena; Häussinger, Dieter; Scheller, Jürgen; Pandyra, Aleksandra A.; Lang, Karl S.; Lang, Philipp A.
    iRhom2 inhibits bile duct obstruction-induced liver fibrosis
    In: Science Signaling Jg. 12 (2019) Nr. 605, eaax1194
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  • Behnke, Kristina; Zhuang, Yuan; Xu, Haifeng C.; Sundaram, Balamurugan; Reich, Maria; Shinde, Prashant V.; Huang, Jun; Modares, Nastaran Fazel; Tumanov, Alexei V.; Polz, Robin; Scheller, Jürgen; Ware, Carl F.; Pfeffer, Klaus; Keitel, Verena; Häussinger, Dieter; Pandyra, Aleksandra A.; Lang, Karl S.; Lang, Philipp A.
    B Cell-Mediated Maintenance of Cluster of Differentiation 169–Positive Cells Is Critical for Liver Regeneration
    In: Hepatology Jg. 68 (2018) Nr. 6, S. 2348 - 2361
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  • Khairnar, Vishal; Duhan, Vikas; Patil, Ashwini M.; Zhou, Fan; Bhat, Hilal; Thoens, Christine; Sharma, Piyush; Adomati, Tom; Friendrich, Sarah-Kim; Bezgovsek, Judith; Dreesen, Janine D.; Wennemuth, Gunther; Westendorf, Astrid; Zelinskyy, Gennadiy; Dittmer, Ulf; Hardt, Cornelia; Timm, Jörg; Göthert, Joachim Rudolf; Lang, Philipp A.; Singer, Bernhard B.; Lang, Karl S.
    CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infection
    In: Nature Communications Jg. 9 (2018) 2561
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  • Horst, Andrea Kristina; Wegscheid, Claudia; Schaefers, Christoph; Schiller, Birgit; Neumann, Katrin; Lunemann, Sebastian; Langeneckert, Annika E; Oldhafer, Karl J; Weiler-Normann, Christina; Lang, Karl S.; Singer, Bernhard B.; Altfeld, Marcus; Diehl, Linda; Tiegs, Gisa
    Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice
    In: Hepatology Jg. 68 (2018) Nr. 1, S. 200 - 214
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  • Lang, Elisabeth; Pozdeev, Vitaly I.; Shinde, Prashant V.; Xu, Haifeng C.; Sundaram, Balamurugan; Zhuang, Yuan; Poschmann, Gereon; Huang, Jun; Stühler, Kai; Pandyra, Aleksandra A.; Keitel, Verena; Häussinger, Dieter; Lang, Karl S.; Lang, Philipp A.
    Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection.
    In: Scientific Reports Jg. 8 (2018) Nr. 1, S. 12179
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  • van Dinther, Dieke; Veninga, Henrike; Iborra, Salvador; Borg, Ellen G.F.; Hoogterp, Leoni; Olesek, Katarzyna; Beijer, Marieke R.; Schetters, Sjoerd T.T.; Kalay, Hakan; Garcia-Vallejo, Juan J.; Franken, Kees L.; Cham, Lamin B.; Lang, Karl S.; van Kooyk, Yvette; Sancho, David; Crocker, Paul R.; den Haan, Joke M.M.
    Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming
    In: Cell Reports Jg. 22 (2018) Nr. 6, S. 1484 - 1495
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  • Knuschke, Torben; Rotan, Olga; Bayer, Wibke; Kollenda, Sebastian; Dickow, Julia; Sutter, Kathrin; Hansen, Wiebke; Dittmer, Ulf; Lang, Karl S.; Epple, Matthias; Buer, Jan; Westendorf, Astrid
    Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral Infection
    In: Frontiers in Immunology Jg. 9 (2018) 614
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  • Bezgovsek, Judith; Gulbins, Erich; Friedrich, Sarah-Kim; Lang, Karl S.; Duhan, Vikas
    Sphingolipids in early viral replication and innate immune activation
    In: Biological Chemistry Jg. 399 (2018) Nr. 10, S. 1115 - 1123
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    The probacterial effect of type I interferon signaling requires its own negative regulator USP18
    In: Science Immunology Jg. 3 (2018) Nr. 27, S. eaau2125
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  • Shinde, Prashant V.; Xu, Haifeng C.; Maney, Sathish Kumar; Kloetgen, Andreas; Namineni, Sukumar; Zhuang, Yuan; Honke, Nadine; Shaabani, Namir; Bellora, Nicolas; Doerrenberg, Mareike; Trilling, Mirko; Pozdeev, Vitaly I.; van Rooijen, Nico; Scheu, Stefanie; Pfeffer, Klaus; Crocker, Paul R.; Tanaka, Masato; Duggimpudi, Sujitha; Knolle, Percy; Heikenwalder, Mathias; Ruland, Jürgen; Mak, Tak W.; Brenner, Dirk; Pandyra, Aleksandra A.; Hoell, Jessica I.; Borkhardt, Arndt; Häussinger, Dieter; Lang, Karl S.; Lang, Philipp A.
    Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection
    In: Journal of Virology Jg. 92 (2018) Nr. 3, S. e01637 - 17
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  • Kuffour, Edmund Osei; Schott, Kerstin; Vasudevan, Ananda Ayyappan Jaguva; Holler, Jessica; Schulz, Wolfgang A.; Lang, Philipp A.; Lang, Karl S.; Kim, Baek; Häussinger, Dieter; König, Renate; Münk, Carsten
    USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1
    In: Journal of Virology Jg. 92 (2018) Nr. 20, e00592
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  • Saroha, Ashish; Pewzner-Jung, Yael; Ferreira, Natalia S.; Sharma, Piyush; Jouan, Youenn; Kelly, Samuel L.; Feldmesser, Ester; Merrill, Alfred H.; Trottein, François; Paget, Christophe; Lang, Karl S.; Futerman, Anthony H.
    Critical role for very-long chain sphingolipids in invariant natural killer T cell development and homeostasis
    In: Frontiers in Immunology Jg. 8 (2017) S. 1386
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  • Honke, Nadine; Shaabani, Namir; Hardt, Cornelia; Krings, Caroline; Häussinger, Dieter; Lang, Philipp A.; Lang, Karl S.; Keitel, Verena
    Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection
    In: Cellular Physiology and Biochemistry Jg. 41 (2017) Nr. 1, S. 323 - 338
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  • Tran, Charles W.; Saibil, Samuel D.; Bihan, Thierry Le; Hamilton, Sara R.; Lang, Karl S.; You, Han; Lin, Amy E.; Garza, Kristine M.; Elford, Alisha R.; Tai, Kelly; Parsons, Michael E.; Wigmore, Kip; Vainberg, Mitchell G.; Penninger, Josef M.; Woodgett, James R.; Mak, Tak W.; Ohashi, Pamela S.
    Glycogen synthase kinase-3 modulates Cbl-b and constrains T cell activation
    In: The Journal of Immunology (JI) Jg. 199 (2017) Nr. 12, S. 4056 - 4065
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  • Huber, Magdalena; Suprunenko, Tamara; Ashhurst, Thomas; Marbach, Felix; Raifer, Hartmann; Wolff, Svenja; Strecker, Thomas; Viengkhou, Barney; Jung, So Ri; Obermann, Hannah-Lena; Bauer, Stefan; Xu, Haifeng C.; Lang, Philipp A.; Tom, Adomati; Lang, Karl S.; King, Nicholas J.C.; Campbell, Iain L.; Hofer, Markus J.
    IRF9 prevents CD8+ T cell exhaustion in an extrinsic manner during acute lymphocytic choriomeningitis virus infection
    In: Journal of Virology Jg. 91 (2017) Nr. 22, S. e01219 - 17
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  • Xu, Haifeng C.; Huang, Jun; Pandyra, Aleksandra A.; Lang, Elisabeth; Zhuang, Yuan; Thöns, Christine; Timm, Jörg; Häussinger, Dieter; Colonna, Marco; Cantor, Harvey; Lang, Karl S.; Lang, Philipp A.
    Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection
    In: Cell Reports Jg. 21 (2017) Nr. 9, S. 2528 - 2540
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  • Brüstle, A.; Brenner, D.; Knobbe-Thomsen, C. B.; Cox, M.; Lang, P. A.; Lang, Karl S.; Mak, T. W.
    MALT1 is an intrinsic regulator of regulatory T cells
    In: Cell Death and Differentiation Jg. 24 (2017) Nr. 7, S. 1214 - 1223
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  • Honke, Nadine; Shaabani, Namir; Teijaro, John R.; Christen, Urs; Hardt, Cornelia; Bezgovsek, Judith; Lang, Philipp A.; Lang, Karl S.
    Presentation of autoantigen in peripheral lymph nodes is sufficient for priming autoreactive CD8+ T cells
    In: Frontiers in Immunology Jg. 8 (2017) S. 113
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  • Sharma, Piyush; Khairnar, Vishal; Madunić, Ivana Vrhovac; Singh, Yogesh; Pandyra, Aleksandra; Salker, Madhuri S.; Koepsell, Hermann; Sabolić, Ivan; Lang, Florian; Lang, Philipp A.; Lang, Karl S.
    SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
    In: Cellular Physiology and Biochemistry Jg. 42 (2017) Nr. 4, S. 1358 - 1365
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  • Kalkavan, Halime; Sharma, Piyush; Kasper, Stefan; Helfrich, Iris; Pandyra, Aleksandra A.; Gassa, Asmae; Virchow, Isabel; Flatz, Lukas; Brandenburg, Tim; Namineni, Sukumar; Heikenwalder, Mathias; Höchst, Bastian; Knolle, Percy A.; Wollmann, Guido; Von Laer, Dorothee; Drexler, Ingo; Rathbun, Jessica; Cannon, Paula M.; Scheu, Stefanie; Bauer, Jens; Chauhan, Jagat; Häussinger, Dieter; Willimsky, Gerald; Löhning, Max; Schadendorf, Dirk; Brandau, Sven; Schuler, Martin; Lang, Philipp A.; Lang, Karl S.
    Spatiotemporally restricted arenavirus replication induces immune surveillance and type i interferon-dependent tumour regression
    In: Nature Communications Jg. 8 (2017) S. 14447
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  • Pozdeev, Vitaly I; Lang, Elisabeth; Görg, Boris; Bidmon, Hans J; Shinde, Prashant V; Kircheis, Gerald; Herebian, Diran; Pfeffer, Klaus; Lang, Florian; Häussinger, Dieter; Lang, Karl S.; Lang, Philipp A
    TNFα induced up-regulation of Na+,K+,2Cl- cotransporter NKCC1 in hepatic ammonia clearance and cerebral ammonia toxicity.
    In: Scientific Reports Jg. 7 (2017) S. 7938
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  • Ungerechts, Guy; Engeland, Christine E.; Buchholz, Christian J.; Eberle, Jürgen; Fechner, Henry; Geletneky, Karsten; Holm, Per Sonne; Kreppel, Florian; Kühnel, Florian; Lang, Karl S.; Leber, Mathias F.; Marchini, Antonio; Moehler, Markus; Mühlebach, Michael D.; Rommelaere, Jean; Springfeld, Christoph; Lauer, Ulrich M.; Nettelbeck, Dirk M.
    Virotherapy research in Germany : from engineering to translation
    In: Human Gene Therapy Jg. 28 (2017) Nr. 10, S. 800 - 819
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  • Singh, Yogesh; Zhou, Yuetao; Shi, Xiaolong; Zhang, Shaqiu; Umbach, Anja T; Salker, Madhuri S; Lang, Karl S.; Lang, Florian
    Alkaline Cytosolic pH and High Sodium Hydrogen Exchanger 1 (NHE1) Activity in Th9 Cells
    In: The Journal of Biological Chemistry (JBC) Jg. 291 (2016) Nr. 45, S. 23662 - 23671
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  • Lang, Elisabeth; Pozdeev, Vitaly I; Gatidis, Sergios; Qadri, Syed M; Häussinger, Dieter; Kubitz, Ralf; Herebian, Diran; Mayatepek, Ertan; Lang, Florian; Lang, Karl S.; Lang, Philipp A
    Bile Acid-Induced Suicidal Erythrocyte Death
    In: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 4, S. 1500 - 1509
    Online Volltext: dx.doi.org/ (Open Access)
  • Shaabani, Namir; Duhan, Vikas; Khairnar, Vishal; Gassa, Asmae; Ferrer-Tur, Rita; Häussinger, Dieter; Recher, Mike; Zelinskyy, Gennadiy; Liu, Jia; Dittmer, Ulf; Trilling, Mirko; Scheu, Stefanie; Hardt, Cornelia; Lang, Philipp A; Honke, Nadine; Lang, Karl S.
    CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection
    In: Cell Death and Disease Jg. 7 (2016) Nr. 11, e2446
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  • Bhavsar, Shefalee K; Singh, Yogesh; Sharma, Piyush; Khairnar, Vishal; Hosseinzadeh, Zohreh; Zhang, Shaqiu; Palmada, Monica; Sabolic, Ivan; Koepsell, Hermann; Lang, Karl S.; Lang, Philipp A; Lang, Florian
    Expression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T Lymphocytes
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 3, S. 1209 - 1228
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  • Gassa, Asmae; Kalkavan, Halime; Jian, Fu; Duhan, Vikas; Khairnar, Vishal; Shaabani, Namir; Honke, Nadine; Carpinteiro, Alexander; Botezatu, Lacramioara; Crivello, Pietro; Dolff, Sebastian; Ferencik, Stanislav; Häussinger, Dieter; Khandanpour, Cyrus; Fleischhauer, Katharina; Witzke, Oliver; Wahlers, Thorsten; Hardt, Cornelia; Lang, Philipp A; Lang, Karl S.
    High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model
    In: Cellular Physiology and Biochemistry Jg. 38 (2016) Nr. 4, S. 1343 - 1353
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  • Wadwa, Munisch-Kumar; Klopfleisch, R; Adamczyk, A; Frede, A; Pastille, Eva; Mahnke, K; Hansen, Wiebke; Geffers, R; Lang, Karl S.; Buer, Jan; Büning, J; Westendorf, Astrid
    IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sites
    In: Mucosal Immunology Jg. 9 (2016) Nr. 5, S. 1263 - 1277
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  • Honke, Nadine; Shaabani, Namir; Merches, Katja; Gassa, Asmae; Kraft, Anke R. M.; Ehrhardt, Katrin; Häussinger, Diéter; Löhning, Max; Dittmer; Hengel, Hartmut; Recher, Mike; Lang, Philipp A.; Lang, Karl S.
    Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses
    In: European Journal of Immunology Jg. 46 (2016) Nr. 2, S. 372 - 380
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  • Vitner, Einat B.; Farfel-Becker, Tamar; Ferreira, Natalia Santos; Leshkowitz, Dena; Sharma, Piyush; Lang, Karl S.; Futerman, Anthony H.
    Induction of the type I interferon response in neurological forms of Gaucher disease
    In: Journal of Neuroinflammation Jg. 13 (2016) 104
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  • Honke, Nadine; Shaabani, Namir; Zhang, Dong-Er; Hardt, Cornelia; Lang, Karl S.
    Multiple functions of USP18
    In: Cell Death and Disease Jg. 7 (2016) Nr. 11, e2444
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  • Maney, Sathish Kumar; Xu, Haifeng C; Huang, Jun; Pandyra, Aleksandra A; Ehlting, Christian; Aguilar-Valenzuela, Renan; Pozdeev, Vitaly I; McIlwain, David R; Zimmermann, Albert; Bode, Johannes G; Hengel, Hartmut; Kirschning, Carsten Jürgen; Kim, Ira R; Hiscott, John; Brenner, Dirk; Häussinger, Dieter; Ohashi, Pamela S; Mak, Tak W; Lang, Karl S.; Lang, Philipp A
    RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 4, S. 1271 - 1280
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  • Lang, Elisabeth; Pozdeev, Vitaly I; Xu, Haifeng C; Shinde, Prashant V; Behnke, Kristina; Hamdam, Junnat M; Lehnert, Erik; Scharf, Rüdiger E; Lang, Florian; Häussinger, Dieter; Lang, Karl S.; Lang, Philipp A
    Storage of Erythrocytes Induces Suicidal Erythrocyte Death
    In: Cellular Physiology and Biochemistry Jg. 39 (2016) Nr. 2, S. 668 - 676
    Online Volltext: dx.doi.org/ (Open Access)
  • Beyer, Marc; Abdullah, Zeinab; Chemnitz, Jens M; Maisel, Daniela; Sander, Jil; Lehmann, Clara; Thabet, Yasser; Shinde, Prashant V; Schmidleithner, Lisa; Köhne, Maren; Trebicka, Jonel; Schierwagen, Robert; Hofmann, Andrea; Popov, Alexey; Lang, Karl S.; Oxenius, Annette; Buch, Thorsten; Kurts, Christian; Heikenwalder, Mathias; Fätkenheuer, Gerd; Lang, Philipp A; Hartmann, Pia; Knolle, Percy A; Schultze, Joachim L
    Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection
    In: Nature Immunology Jg. 17 (2016) Nr. 5, S. 593 - 603
    Online Volltext: dx.doi.org/
  • Shaabani, Namir; Khairnar, Vishal; Duhan, Vikas; Zhou, Fan; Tur, Rita Ferrer; Häussinger, Dieter; Recher, Mike; Tumanov, Alexei V; Hardt, Cornelia; Pinschewer, Daniel; Christen, Urs; Lang, Philipp A; Honke, Nadine; Lang, Karl S.
    Two separate mechanisms of enforced viral replication balance innate and adaptive immune activation
    In: Journal of Autoimmunity Jg. 67 (2016) S. 82 - 89
    Online Volltext: dx.doi.org/
  • Duhan, Vikas; Khairnar, Vishal; Friedrich, Sarah-Kim; Zhou, Fan; Gassa, Asmae; Honke, Nadine; Shaabani, Namir; Gailus, Nicole; Botezatu, Lacramioara; Khandanpour, Cyrus; Dittmer, Ulf; Haüssinger, Dieter; Recher, Mike; Hardt, Cornelia; Lang, Philipp A.; Lang, Karl S.
    Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8 + T-cell priming and viral control
    In: Scientific Reports Jg. 6 (2016) 19191
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Karl S.; Lang, Philipp A.
    Balancing viral replication in spleen and liver determines the outcome of systemic virus infection
    In: Zeitschrift für Gastroenterologie Jg. 53 (2015) Nr. 12, S. 1432 - 1435
    Online Volltext: dx.doi.org/
  • Khairnar, Vishal; Duhan, Vikas; Kumar Maney, Sathish; Seifert, Marc; Kirschning, Carsten; Westendorf, Astrid M.; Dittmer, Ulf; Küppers, Ralf; Scheffrahn, Inka; Göthert, Joachim R.; Singer, Bernhard B.; Lang, Karl S.; et al.
    CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
    In: Nature Communications Jg. 6 (2015) 6217
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Elisabeth; Gatidis, Sergios; Freise, Noemi F; Bock, Hans; Kubitz, Ralf; Lauermann, Christian; Orth, Hans Martin; Klindt, Caroline; Schuier, Maximilian; Keitel, Verena; Reich, Maria; Liu, Guilai; Schmidt, Sebastian; Xu, Haifeng C; Qadri, Syed M; Herebian, Diran; Pandyra, Aleksandra A; Mayatepek, Ertan; Gulbins, Erich; Lang, Florian; Häussinger, Dieter; Lang, Karl S.; Föller, Michael; Lang, Philipp A
    Conjugated Bilirubin Triggers Anemia by Inducing Erythrocyte Death
    In: Hepatology Jg. 61 (2015) Nr. 1, S. 275 - 284
    Online Volltext: dx.doi.org/ (Open Access)
  • Akhmetzyanova, Ilseyar; Drabczyk, Malgorzata; Neff, C Preston; Gibbert, Kathrin; Dietze, Kirsten; Werner, Tanja; Liu, Jia; Chen, Lieping; Lang, Karl S.; Palmer, Brent E; Dittmer, Ulf; Zelinskyy, Gennadiy
    Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing
    In: PLoS Pathogens Jg. 11 (2015) Nr. 12, e1005364
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Haifeng C.; Huang, Jun; Khairnar, Vishal; Duhan, Vikas; Pandyra, Aleksandra A.; Grusdat, Melanie; Shinde, Prashant; McIlwain, David R.; Maney, Sathish Kumar; Gommerman, Jennifer; Löhning, Max; Ohashi, Pamela S.; Mak, Tak W.; Pieper, Kathrin; Sic, Heiko; Speletas, Matthaios; Eibel, Hermann; Ware, Carl F.; Tumanov, Alexei V.; Kruglov, Andrey A.; Nedospasov, Sergei A.; Häussinger, Dieter; Recher, Mike; Lang, Karl S.; Lang, Philipp A.
    Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection
    In: Journal of Virology Jg. 89 (2015) Nr. 9, S. 4748 - 4759
    Online Volltext: dx.doi.org/ (Open Access)
  • Maney, Sathish Kumar; McIlwain, David R.; Polz, Robin; Pandyra, Aleksandra A.; Sundaram, Balamurugan M.; Wolff, Dorit; Ohishi, Kazuhito; Maretzky, Thorsten; Brooke, Matthew A.; Evers, Astrid; Jaguva Vasudevan, Ananda A.; Aghaeepour, Nima; Scheller, Jürgen; Münk, Carsten; Häussinger, Dieter; Mak, Tak W.; Nolan, Garry P.; Kelsell, David P.; Blobel, Carl Peter; Lang, Karl S.; Lang, Philipp A.
    Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17
    In: Science Signaling Jg. 8 (2015) Nr. 401, S. ra109
    Online Volltext: dx.doi.org/
  • Pandyra, Aleksandra A.; Mullen, Peter J.; Goard, Carolyn A.; Ericson, Elke; Sharma, Piyush; Kalkat, Manpreet; Yu, Rosemary; Pong, Janice T.; Brown, Kevin R.; Hart, Traver; Gebbia, Marinella; Lang, Karl S.; Giaever, Guri; Nislow, Corey; Moffat, Jason; Penn, Linda Z.
    Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death
    In: OncoTarget Jg. 6 (2015) Nr. 29, S. 26909 - 26921
    Online Volltext: dx.doi.org/ (Open Access)
  • Qvartskhava, Natalia; Lang, Philipp A.; Görg, Boris; Pozdeev, Vitaly I.; Pascual Ortiz, Marina; Lang, Karl S.; Bidmon, Hans J.; Lang, Elisabeth; Leibrock, Christina B.; Herebian, Diran; Bode, Johannes G.; Lang, Florian; Häussinger, Dieter
    Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 17, S. 5521 - 5526
    Online Volltext: dx.doi.org/ (Open Access)
  • Shaabani, Namir; Honke, Nadine; Dolff, Sebastian; Görg, Boris; Khairnar, Vishal; Merches, Katja; Duhan, Vikas; Metzger, Sabine; Recher, Mike; Barthuber, Carmen; Hardt, Cornelia; Proksch, Peter; Häussinger, Dieter; Witzke, Oliver; Lang, Philipp A.; Lang, Karl S.
    IFN-γ licenses CD11b+ cells to induce progression of systemic lupus erythematosus
    In: Journal of Autoimmunity Jg. 62 (2015) S. 11 - 21
    Online Volltext: dx.doi.org/
  • Kubagawa, Hiromi; Carroll, Michael C; Jacob, Chaim O; Lang, Karl S.; Lee, Kyeong-Hee; Mak, Tak; McAndrews, Monica; Morse, Herbert C; Nolan, Garry P; Ohno, Hiroshi; Richter, Günther H; Seal, Ruth; Wang, Ji-Yang; Wiestner, Adrian; Coligan, John E
    Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR
    In: The Journal of Immunology (JI) Jg. 194 (2015) Nr. 9, S. 4055 - 4057
    Online Volltext: dx.doi.org/
  • Akhmetzyanova, Ilseyar; Drabczyk, Malgorzata; Neff, C Preston; Gibbert, Kathrin; Dietze, Kirsten; Werner, Tanja; Liu, Jia; Chen, Lieping; Lang, Karl S.; Palmer, Brent E; Dittmer, Ulf; Zelinskyy, Gennadiy
    PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing
    In: PLoS Pathogens Jg. 11 (2015) Nr. 10, e1005224
    Online Volltext: dx.doi.org/ (Open Access)
  • McIlwain, David R.; Grusdat, Melanie; Pozdeev, Vitaly I.; Xu, Haifeng C.; Shinde, Prashant; Reardon, Colin; Hao, Zhenyue; Beyer, Marc; Bergthaler, Andreas; Häussinger, Dieter; Nolan, Garry P.; Lang, Karl S.; Lang, Philipp A.
    T-cell STAT3 is required for the maintenance of humoral immunity to LCMV
    In: European Journal of Immunology Jg. 45 (2015) Nr. 2, S. 418 - 427
    Online Volltext: dx.doi.org/ (Open Access)
  • Wu, Weimin; Dietze, Kirsten; Gibbert, Kathrin; Lang, Karl S.; Trilling, Mirko; Yan, Huimin; Wu, Jun; Yang, Dongliang; Lu, Mengji; Roggendorf, Michael; Dittmer, Ulf; Liu, Jia
    TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infection
    In: Scientific Reports Jg. 5 (2015) 10501
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lang, P A; Meryk, A; Pandyra, A A; Brenner, D; Brüstle, A; Xu, H C; Merches, K; Lang, F; Khairnar, V; Sharma, P; Funkner, P; Recher, M; Shaabani, N; Duncan, G S; Duhan, V; Homey, B; Ohashi, P S; Häussinger, D; Knolle, P A; Honke, N; Mak, T W; Lang, Karl S.
    Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection
    In: Cell Death and Differentiation Jg. 22 (2015) Nr. 1, S. 164 - 173
    Online Volltext: dx.doi.org/
  • Warsi, Jamshed; Hosseinzadeh, Zohreh; Elvira, Bernat; Pelzl, Lisann; Shumilina, Ekaterina; Zhang, Dong-Er; Lang, Karl S.; Lang, Philipp A.; Lang, Florian
    USP18 sensitivity of peptide transporters PEPT1 and PEPT2
    In: PLoS ONE Jg. 10 (2015) Nr. 6, e0129365
    Online Volltext: dx.doi.org/ (Open Access)
  • Merches, Katja; Khairnar, Vishal; Knuschke, Torben; Shaabani, Namir; Honke, Nadine; Duhan, Vikas; Recher, Mike; Navarini, Alexander A.; Hardt, Cornelia; Häussinger, Dieter; Tümmler, Burkhard; Gulbins, Erich; Futerman, Anthony H.; Hoffmann, Daniel; Lang, Florian; Lang, Philipp A.; Westendorf, Astrid; Lang, Karl S.
    Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infection
    In: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 6, S. 2379 - 2392
    Online Volltext: dx.doi.org/ (Open Access)
  • Joedicke, JaraJ; Myers, Lara; Carmody, AaronB; Messer, RonaldJ; Wajant, Harald; Lang, Karl S.; Lang, PhilippA; Mak, TakW; Hasenkrug, KimJ; Dittmer, Ulf
    Activated CD8+ T Cells Induce Expansion of Vβ5+ Regulatory T Cells via TNFR2 Signaling
    In: The Journal of Immunology (JI) Jg. 193 (2014) Nr. 6, S. 2952 - 2960
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Göbel, C.; Breitenbücher, Frank; Kalkavan, Halime; Hähnel, Patricia S.; Kasper, Stefan; Hoffarth, Christian; Merches, Katja; Schild, Hans-Jörg; Lang, Karl S.; Schuler, Martin
    Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunity
    In: Cell Death and Disease Jg. 5 (2014) Nr. 12, 1568
    Online Volltext: dx.doi.org/ (Open Access)
  • Grusdat, M.; McIlwain, D. R.; Xu, H. C.; Pozdeev, V. I.; Knievel, J.; Crome, S. Q.; Robert-Tissot, C.; Dress, R. J.; Pandyra, A. A.; Speiser, D. E.; Lang, E.; Maney, S. K.; Elford, A. R.; Hamilton, S. R.; Scheu, S.; Pfeffer, K.; Bode, J.; Mittrücker, H.-W.; Lohoff, M.; Huber, M.; Häussinger, D.; Ohashi, P. S.; Mak, T. W.; Lang, Karl S.; Lang, P. A.
    IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV
    In: Cell Death and Differentiation Jg. 21 (2014) Nr. 7, S. 1050 - 1060
    Online Volltext: dx.doi.org/ (Open Access)
  • Pandyra, Aleksandra; Mullen, Peter J.; Kalkat, Manpreet; Yu, Rosemary; Pong, Janice T.; Li, Zhihua; Trudel, Suzanne; Lang, Karl S.; Minden, Marc D.; Schimmer, Aaron D.; Penn, Linda Z.
    Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop
    In: Cancer Research Jg. 74 (2014) Nr. 17, S. 4772 - 4782
    Online Volltext: dx.doi.org/
  • Brenner, D.; Brüstle, A.; Lin, Gloria; Lang, P. A.; Duncan, G. S.; Knobbe-Thomsen, C. B.; Paul, M. S.; Reardon, C.; Tusche, M. W.; Snow, B.; Hamilton, S. R.; Pfefferle, A.; Gilani, S. O.; Ohashi, P. S.; Lang, Karl S.; Mak, T. W.
    Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 111 (2014) Nr. 3, S. 1060 - 1065
    Online Volltext: dx.doi.org/
  • Xu, Haifeng C; Grusdat, Melanie; Pandyra, Aleksandra A; Polz, Robin; Huang, Jun; Sharma, Piyush; Deenen, René; Köhrer, Karl; Rahbar, Ramtin; Diefenbach, Andreas; Gibbert, Kathrin; Löhning, Max; Höcker, Lena; Waibler, Zoe; Häussinger, Dieter; Mak, Tak W; Ohashi, Pamela S; Lang, Karl S.; Lang, Philipp A
    Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity
    In: Immunity Jg. 40 (2014) Nr. 6, S. 949 - 960
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Karl S.; Lang, Philipp A.; Meryk, Andreas; Pandyra, Aleksandra A.; Boucher, Louis-Martin; Pozdeev, Vitaly I.; Tusche, Michael W.; Göthert, Joachim Rudolf; Haight, Jilian; Wakeham, Andrew; You-Ten, Annick J.; McIlwain, David R.; Merches, Katja; Khairnar, Vishal; Recher, Mike; Nolan, Garry P.; Hitoshi, Yasumichi; Funkner, Pauline; Navarini, Alexander A.; Verschoor, Admar; Shaabani, Namir; Honke, Nadine; Penn, Linda Z.; Ohashi, Pamela S.; Häussinger, Dieter; Lee, Kyeong-Hee; Mak, Tak W.
    Involvement of Toso in activation of monocytes, macrophages, and granulocytes
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 110 (2013) Nr. 7, S. 2593 - 2598
    Online Volltext: dx.doi.org/
  • Crome, Sarah Q; Lang, Philipp A; Lang, Karl S.; Ohashi, Pamela S
    Natural killer cells regulate diverse T cell responses
    In: Trends in Immunology Jg. 34 (2013) Nr. 7, S. 342 - 349
    Online Volltext: dx.doi.org/
  • Lang, Philipp; Xu, Haifeng C.; Grusdat, Melanie; McIlwain, David R.; Pandyra, Aleksandra A.; Harris, Isaac S.; Shaabani, Namir; Honke, Nadine; Kumar Maney, S.; Lang, Elisabeth; Pozdeev, Vitaly I.; Recher, Mike; Odermatt, Bernhard F.; Brenner, Dirk L.; Häussinger, Diéter; Ohashi, Pamela; Hengartner, Hans H.; Zinkernagel, Rolf Martin; Mak, Tak W.; Lang, Karl S.
    Reactive oxygen species delay control of lymphocytic choriomeningitis virus
    In: Cell Death and Differentiation Jg. 20 (2013) Nr. 4, S. 649 - 658
    Online Volltext: dx.doi.org/
  • Lang, Philipp A.; Shaabani, Namir; Borkens, Stephanie; Honke, Nadine; Scheu, Stefanie; Booth, Sarah; Brenner, Dirk; Meryk, Andreas; Barthuber, Carmen; Recher, Mike; Mak, Tak W.; Ohashi, Pamela S.; Häussinger, Dieter; Griffiths, Gillian M.; Thrasher, Adrian J.; Bouma, Gerben; Lang, Karl S.
    Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency
    In: The Journal of Allergy and Clinical Immunology Jg. 131 (2013) Nr. 3, S. 815 - 824.e2
    Online Volltext: dx.doi.org/
  • Lang, Karl S.; Lang, Philipp A.; Meryk, Andreas; Pandyra, Aleksandra A.; Merches, Katja; Lee, Kyeong-Hee; Mak, Tak W.
    Reply to Honjo et al.: Functional relevant expression of Toso on granulocytes
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 110 (2013) Nr. 28, S. E2542 - E2543
    Online Volltext: dx.doi.org/
  • Honke, Nadine; Shaabani, Namir; Zhang, Dong-Er; Iliakis, George; Xu, Haifeng C.; Häussinger, Dieter; Recher, Mike; Löhning, Max; Lang, Philipp A.; Lang, Karl S.
    Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes
    In: PLoS Pathogens Jg. 9 (2013) Nr. 10,
    Online Volltext: dx.doi.org/ (Open Access)
  • Nguyen, X. H.; Fattakhova, G.; Lang, P. A.; Lang, Karl S.; Adam, D.; Föger, N.; Lee, K. H.
    Antiapoptotic function of Toso (Faim3) in death receptor signaling
    In: Blood Jg. 119 (2012) Nr. 7, S. 1790 - 1791
    Online Volltext: dx.doi.org/
  • Recher, Mike; Burns, Siobhan O.; De La Fuente, Miguel A.; Volpi, Stefano; Dahlberg, Carin; Walter, Jolan E.; Moffitt, Kristin; Mathew, Divij; Honke, Nadine; Lang, Philipp A.; Patrizi, Laura; Falet, Hervé; Keszei, Marton; Mizui, Masayuki; Csizmadia, Eva; Candotti, Fabio; Nadeau, Kari; Bouma, Gerben; Delmonte, Ottavia M.; Frugoni, Francesco; Ferraz Fomin, Angela B.; Buchbinder, David; Lundequist, Emma Maria; Massaad, Michel J.; Tsokos, George C.; Hartwig, John; Manis, John; Terhorst, Cox; Geha, Raif S.; Snapper, Scott; Lang, Karl S.; Malley, Richard; Westerberg, Lisa; Thrasher, Adrian J.; Notarangelo, Luigi D.
    B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice
    In: Blood Jg. 119 (2012) Nr. 12, S. 2819 - 2828
    Online Volltext: dx.doi.org/
  • Kaesler, S.; Sobiesiak, M.; Kneilling, M.; Volz, T.; Kempf, W. E.; Lang, P. A.; Lang, Karl S.; Wieder, T.; Heller-Stilb, B.; Warskulat, U.; Häussinger, D.; Lang, F.; Biedermann, T.
    Effective T-cell recall responses require the taurine transporter Taut
    In: European Journal of Immunology Jg. 42 (2012) Nr. 4, S. 831 - 841
    Online Volltext: dx.doi.org/
  • Honke, Nadine; Shaabani, Namir; Cadeddu, Giuseppe; Sorg, Ursula R.; Zhang, Dong-Er; Trilling, Mirko; Klingel, Karin; Sauter, Martina; Kandolf, Reinhard; Gailus, Nicole; Van Rooijen, Nico; Burkart, Christoph; Baldus, Stephan E.; Grusdat, Melanie; Löhning, Max; Hengel, Hartmut; Pfeffer, Klaus; Tanaka, Masato; Häussinger, Dieter; Recher, Mike; Lang, Philipp A.; Lang, Karl S.
    Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus
    In: Nature Immunology Jg. 13 (2012) Nr. 1, S. 51 - 57
    Online Volltext: dx.doi.org/
  • Lang, Karl S.; Lang, P. A.; Shaabani, N.; Honke, N.
    Enforced virus replication' as an immunological mechanism for adaptive immune activation
    In: Immunology Jg. 137 (2012) Nr. Suppl. 1, S. 633 - 633
  • Gibbert, Kathrin; Joedicke, Jara J.; Meryk, Andreas; Trilling, Mirko; Francois, Sandra; Duppach, Janine; Kraft, Anke; Lang, Karl S.; Dittmer, Ulf
    Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral Infection
    In: PLoS Pathogens Jg. 8 (2012) Nr. 8, S. e1002868
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lang, P. A.; Lang, Karl S.; Xu, H. C.; Grusdat, M.; Tran, C. W.; Dissanayake, D.; Rahbar, R.; Ghazarian, M.; Brustle, A.; Weaver, C. T.; Klose, C.; Diefenbach, A.; Parish, I. A.; Kaech, S. M.; Fine, J.; Shaabani, N.; Carlyle, J. R.; Haussinger, D.; Mak, T. W.; Ohashi, P. S.
    NK cells promote chronic viral infection
    In: Immunology Jg. 137 (2012) Nr. Suppl. 1, S. 129 - 129
  • Lang, Philipp A.; Lang, Karl S.; Xu, Haifeng C.; Grusdat, Melanie; Parish, Ian A.; Recher, Mike; Elford, Alisha R.; Dhanji, Salim; Shaabani, Namir; Tran, Charles W.; Dissanayake, Dilan; Rahbar, Ramtin; Ghazarian, Magar; Brüstle, Anne; Fine, Jason; Chen, Peter; Weaver, Casey T.; Klose, Christoph; Diefenbach, Andreas; Häussinger, Dieter; Carlyle, James R.; Kaech, Susan M.; Mak, Tak W.; Ohashi, Pamela S.
    Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8 ⁺ T-cell immunity
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 109 (2012) Nr. 4, S. 1210 - 1215
    Online Volltext: dx.doi.org/ (Open Access)
  • Bouma, G.; Lang, P. A.; Shaabani, N.; Borkens, S.; Scheu, S.; Booth, S.; Honke, N.; Brenner, D.; Meryk, A.; Recher, M.; Mak, T. W.; Ohashi, P. S.; Hausinger, D.; Griffiths, G. M.; Thrasher, A. J.; Lang, Karl S.
    Reduced type I interferon production by dendritic cells and weakened antiviral immunity in Wiskott-Aldrich-Syndrome protein defiency
    In: Journal of Clinical Immunology Jg. 32 (2012) Nr. Suppl. 1, S. 46
  • Chen, Grace; Dimitriou, Ioannis; Milne, Laura; Lang, Karl S.; Lang, Philipp A.; Fine, Noah; Ohashi, Pamela S.; Kubes, Paul; Rottapel, Robert
    The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activation
    In: The Journal of Immunology (JI) Jg. 189 (2012) Nr. 5, S. 2138 - 2150
    Online Volltext: dx.doi.org/
  • Shaabani, Namir; Honke, Nadine; Lang, Philipp A.; Görg, Boris; Proksch, Peter; Gailus, Nicole; Gotoh, Tomomi; Häussinger, Dieter; Lang, Karl S.
    Tunicamycin inhibits diabetes
    In: Cellular Physiology and Biochemistry Jg. 29 (2012) Nr. 3-4, S. 595 - 602
    Online Volltext: dx.doi.org/
  • Lang, P. A.; McIlwain, D. R.; Maretzky, T.; Koichi, H.; Ohishi, K.; Lang, Karl S.; Haussinger, D.; Xu, H. C.; Maney, S. K.; Ohashi, P. S.; Blobel, C. P.; Mak, T. W.
    iRhom2 regulates innate immunity via TACE/ADAM17
    In: Immunology Jg. 137 (2012) Nr. Suppl. 1, S. 147
  • McIlwain, David R.; Lang, Philipp A.; Maretzky, Thorsten; Hamada, Koichi; Ohishi, Kazuhito; Maney, Sathish Kumar; Berger, Thorsten; Murthy, Aditya; Duncan, Gordon; Xu, Haifeng C.; Lang, Karl S.; Häussinger, Dieter; Wakeham, Andrew; Itie-Youten, Annick; Khokha, Rama; Ohashi, Pamela S.; Blobel, Carl P.; Mak, Tak W.
    iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
    In: Science Jg. 335 (2012) Nr. 6065, S. 229 - 232
    Online Volltext: dx.doi.org/
  • Ehlting, C.; Ronkina, N.; Böhmer, O.; Albrecht, U.; Bode, K. A.; Lang, Karl S.; Kotlyarov, A.; Radzioch, D.; Gaestel, M.; Häussinger, D.; Bode, J. G.
    Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3 : MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory ef
    In: The Journal of Biological Chemistry (JBC) Jg. 286 (2011) Nr. 27, S. 24113 - 24124
    Online Volltext: dx.doi.org/
  • Contaldo, C.; Lindenblatt, N.; Elsherbiny, A.; Högger, D. C.; Borozadi, M. K.; Vetter, S. T.; Lang, Karl S.; Handschin, A. E.; Giovanoli, P.
    Erythropoietin Requires Endothelial Nitric Oxide Synthase to Counteract TNF-α-Induced Microcirculatory Dysfunction in Murine Striated Muscle
    In: Shock Jg. 35 (2011) Nr. 3, S. 315 - 321
    Online Volltext: dx.doi.org/
  • Pellegrini, M.; Calzascia, T.; Toe, J. G.; Preston, S. P.; Lin, A. E.; Elford, A. R.; Shahinian, A.; Lang, P. A.; Lang, Karl S.; Morre, M.; Assouline, B.; Lahl, K.; Sparwasser, T.; Tedder, T. F.; Paik, J. H.; DePinho, R. A.; Basta, S.; Ohashi, P. S.; Mak, T. W.
    IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology
    In: Cell Jg. 144 (2011) Nr. 4, S. 601 - 613
    Online Volltext: dx.doi.org/ (Open Access)
  • Gibbert, Kathrin; Joedicke, Jara J.; Meryk, Andreas; Lang, Karl S.; Dittmer, Ulf
    Interferon alpha subtype 11 selectively activates NK cells to enable control of retroviral infection
    In: Cytokine Jg. 56 (2011) Nr. 1, S. 45 - 46
    Online Volltext: dx.doi.org/
  • Nguyen, X. H.; Lang, P. A.; Lang, Karl S.; Adam, D.; Fattakhova, G.; Föger, N.; Kamal, M. A.; Prilla, P.; Mathieu, S.; Wagner, C.; Mak, T.; Chan, A. C.; Lee, K. H.
    Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination
    In: Blood Jg. 118 (2011) Nr. 3, S. 598 - 608
    Online Volltext: dx.doi.org/
  • Gibbert, Kathrin; Dietze, Kirsten; Zelinskyy, Gennadiy; Lang, Karl S.; Barchet, Winfried; Kirschning, Carsten Jürgen; Dittmer, Ulf
    Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease
    In: The Journal of Immunology (JI) Jg. 185 (2010) Nr. 10, S. 6179 - 6189
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Horst, Andrea Kristina; Wegscheid, Claudia; Schaefers, Christoph; Schiller, Birgit; Neumann, Katrin; Lunemann, Sebastian; Langeneckert, Annika E.; Oldhafer, Karl J.; Weiler-Normann, Christina; Schramm, Christoph; Lang, Karl S.; Singer, Bernhard B.; Altfeld, Marcus; Diehl, Linda; Tiegs, Gisa
    Ceacam1 controls IL-2-dependent regulatory T cell induction in immune-mediated hepatitis
    In: Journal of Hepatology Jg. 68 (2018) Nr. Suppl. 1, S. 448
    Online Volltext: dx.doi.org/
  • Geisthoff, Urban; Droege, F.; Koenig, J.; Lang, Karl S.; Thangavelu, K.; Lang, Stephan;
    Increased infection rates in HHT patients : results of an online survey
    12th International HHT Scientific Conference ; June 8–11, 2017, Dubrovnik, Croatia,
    In: Angiogenesis Jg. 21 (2018) Nr. 1, S. 125 - 125
    Online Volltext: dx.doi.org/
  • Lang, Karl S.; Honke, Nadine; Shaabani, Namir; Häussinger, Dieter; Lang, Philipp A.
    Enforced viral replication, a mechanism for immune activation.
    In: European Journal of Medical Research Jg. 19 (2014) Nr. Suppl. 1, S. S26
    Online Volltext: dx.doi.org/ (Open Access)
  • Lang, Philipp; Häussinger, Dieter; Lang, Karl S.
    Immune functions during chronic viral infections
    In: European Journal of Medical Research Jg. 19 (2014) Nr. Suppl. 1, S. S25
    Online Volltext: dx.doi.org/ (Open Access)
  • Meryk, A.; Joedicke, J.J.; Kraft, A.; Dittmer, Ulf; Lang, Karl S.; Gibbert, K.
    Interferon alpha subtype 11 activates NK cells and enables control of retroviral infection
    In: Cytokine Jg. 59 (2012) Nr. 3, S. 498
    Online Volltext: dx.doi.org/

    • Poster / Posterbeiträge

  • Falkenstein, Julia; Buer, Jan; Lang, Karl S.; Hansen, Wiebke;
    Splenic Macrophages are Important for Pathogen Clearance and Induction of T cell Responses during Malaria
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 16
    Online Volltext: dx.doi.org/ (Open Access)