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Prof. Dr. med. Dobromir Dobrev

14

Funktionen

  • Institutsdirektor/in, Institut für Pharmakologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Gawałko, Monika; Saljic, Arnela; Li, Na; Abu-Taha, Issam; Jespersen, Thomas; Linz, Dominik; Nattel, Stanley; Heijman, Jordi; Fender, Anke; Dobrev, Dobromir
    Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance
    In: Cardiovascular Research (2022)
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Coats, Andrew J. S.; Heymans, Stephane; Farmakis, Dimitrios; Anker, Stefan D.; Backs, Johannes; Bauersachs, Johann; de Boer, Rudolf A.; Čelutkienė, Jelena; Cleland, John G. F.; Dobrev, Dobromir; van Gelder, Isabelle C.; von Haehling, Stephan; Hindricks, Gerhard; Jankowska, Ewa; Kotecha, Dipak; van Laake, Linda W.; Lainscak, Mitja; Lund, Lars H.; Lunde, Ida Gjervold; Lyon, Alexander R.; Manouras, Aristomenis; Miličić, Davor; Mueller, Christian; Polovina, Marija; Ponikowski, Piotr; Rosano, Giuseppe; Seferović, Petar M.; Tschöpe, Carsten; Wachter, Rolf; Ruschitzka, Frank
    Atrial disease and heart failure : The common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology
    In: European Heart Journal Jg. 43 (2022) Nr. 9, S. 863 - 867
    ISSN: 0195-668X; 1522-9645
    Online Volltext: dx.doi.org/
  • Harlaar, Niels; Dekker, Sven O.; Zhang, Juan; Snabel, Rebecca R.; Veldkamp, Marieke W.; Verkerk, Arie O.; Fabres, Carla Cofiño; Schwach, Verena; Lerink, Lente J. S.; Rivaud, Mathilde R.; Mulder, Aat A.; Corver, Willem E.; Goumans, Marie José T. H.; Dobrev, Dobromir; Klautz, Robert J. M.; Schalij, Martin J.; Veenstra, Gert Jan C.; Passier, Robert; van Brakel, Thomas J.; Pijnappels, Daniël A.; de Vries, Antoine A. F.
    Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation
    In: Nature Biomedical Engineering Jg. 6 (2022) Nr. 4, S. 389 - 402
    ISSN: 2157-846X
    Online Volltext: dx.doi.org/
  • Saljic, Arnela; Heijman, Jordi; Dobrev, Dobromir
    Emerging Antiarrhythmic Drugs for Atrial Fibrillation
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 8,
    ISSN: 1422-0067; 1661-6596
    Online Volltext: dx.doi.org/ (Open Access)
  • Tamargo, Juan; Kjeldsen, Keld Per; Delpón, Eva; Semb, Anne Grete; Cerbai, Elisabetta; Dobrev, Dobromir; Savarese, Gianluigi; Sulzgruber, Patrick; Rosano, Giuseppe; Borghi, Claudio; Wassman, Seven; Torp-Pedersen, Christian Tobias; Agewall, Stefan; Drexel, Heinz; Baumgartner, Iris; Lewis, Basil; Ceconi, Claudio; Kaski, Juan Carlos; Niessner, Alexander
    Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease : A review by the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy
    In: European Heart Journal - Cardiovascular Pharmacotherapy Jg. 8 (2022) Nr. 4, S. 406 - 419
    ISSN: 2055-6837; 2055-6845
    Online Volltext: dx.doi.org/ (Open Access)
  • Ni, Li; Lahiri, Satadru K.; Nie, Jiali; Pan, Xiaolu; Abu-Taha, Issam; Reynolds, Julia O.; Campbell, Hannah M.; Wang, Haihao; Kamler, Markus; Schmitz, Wilhelm; Müller, Frank Ulrich; Li, Na; Wei, Xiang; Wang, Dao Wen; Dobrev, Dobromir; Wehrens, Xander H. T.
    Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice
    In: Cardiovascular Research (2022) in press
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Geschlechtsspezifische Unterschiede in der Pharmakologie
    In: Aktuelle Kardiologie Jg. 11 (2022) Nr. 1, S. 62 - 66
    ISSN: 2193-5211; 2193-5203
    Online Volltext: dx.doi.org/
  • Gawałko, Monika; Agbaedeng, Thomas A; Saljic, Arnela; Müller, Dominik N; Wilck, Nicola; Schnabel, Renate; Penders, John; Rienstra, Michiel; van Gelder, Isabelle; Jespersen, Thomas; Schotten, Ulrich; Crijns, Harry J G M; Kalman, Jonathan M; Sanders, Prashanthan; Nattel, Stanley; Dobrev, Dobromir; Linz, Dominik
    Gut microbiota, dysbiosis and atrial fibrillation : Arrhythmogenic mechanisms and potential clinical implications
    In: Cardiovascular Research (2022) in press
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Benjamin Fyenbo, Daniel; Charlotte Frederiksen, Tanja; Linz, Dominik; Jespersen, Thomas; Dobrev, Dobromir; Gislason, Gunnar; Betz, Konstanze; Saljic, Arnela; Nielsen Holck, Emil
    Researchers in cardiology : Why and how to get on Twitter?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 40 (2022)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Yamazaki, Masatoshi; Tomii, Naoki; Tsuneyama, Koichi; Takanari, Hiroki; Niwa, Ryoko; Honjo, Haruo; Kodama, Itsuo; Arafune, Tatsuhiko; Makita, Naomasa; Sakuma, Ichiro; Dobrev, Dobromir; Nattel, Stanley; Tsuji, Yukiomi
    Rotors anchored by refractory islands drive torsades de pointes in an experimental model of electrical storm
    In: Heart Rhythm Jg. 19 (2022) Nr. 2,
    ISSN: 1556-3871; 1547-5271
    Online Volltext: dx.doi.org/
  • Linz, Benedikt; Norup Hertel, Julie; Hendriks, Jeroen; Saljic, Arnela; Dobrev, Dobromir; Baumert, Mathias; Jespersen, Thomas; Linz, Dominik
    Sleep apnea and atrial fibrillation : challenges in clinical and translational research
    In: Expert Review of Cardiovascular Therapy Jg. 20 (2022) Nr. 2, S. 101 - 109
    ISSN: 1477-9072; 1744-8344
    Online Volltext: dx.doi.org/ (Open Access)
  • Sutanto, Henry; Dobrev, Dobromir; Heijman, Jordi
    Angiotensin receptor-neprilysin inhibitor (ARNI) and cardiac arrhythmias
    In: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 16,
    ISSN: 1422-0067; 1661-6596
    Online Volltext: dx.doi.org/ (Open Access)
  • Grandi, Eleonora; Dobrev, Dobromir
    Atrial fibrillation in a dish : insights into atrial arrhythmogenesis from induced pluripotent stem cell-derived cardiomyocytes
    In: Cardiovascular Research Jg. 116 (2021) Nr. 6, S. 1089 - 1091
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Hulsurkar, Mohit M.; Lahiri, Satadru K.; Moore, Oliver; Moreira, Lucia M.; Abu-Taha, Issam; Kamler, Markus; Dobrev, Dobromir; Nattel, Stanley; Reilly, Svetlana; Wehrens, Xander H.T.
    Atrial-Specific LKB1 Knockdown Represents a Novel Mouse Model of Atrial Cardiomyopathy With Spontaneous Atrial Fibrillation
    In: Circulation Jg. 144 (2021) Nr. 11, S. 909 - 912
    ISSN: 0065-8499; 1524-4539; 0009-7322
    Online Volltext: dx.doi.org/ (Open Access)
  • Wagner, Michael; Sadek, Mirna S.; Dybkova, Nataliya; Mason, Fleur E.; Klehr, Johann; Firneburg, Rebecca; Cachorro, Eleder; Richter, Kurt; Klapproth, Erik; Kuenzel, Stephan R.; Lorenz, Kristina; Heijman, Jordi; Dobrev, Dobromir; El-Armouche, Ali; Sossalla, Samuel; Kämmerer, Susanne
    Cellular mechanisms of the anti-arrhythmic effect of cardiac pde2 overexpression
    In: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 9, S. 4816
    ISSN: 1422-0067; 1661-6596
    Online Volltext: dx.doi.org/ (Open Access)
  • Nattel, Stanley; Lip, Gregory Y H; Filgueiras-Rama, David; Dobrev, Dobromir
    Challenges and opportunities in improving the management of atrial fibrillation : recent research advances and their clinical translation
    In: Cardiovascular Research Jg. 117 (2021) Nr. 7, S. 1609 - 1611
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Künzel, Stephan R.; Hoffmann, Maximilian; Weber, Silvio; Künzel, Karolina; Kämmerer, Susanne; Günscht, Mario; Klapproth, Erik; Rausch, Johanna S.E.; Sadek, Mirna S.; Kolanowski, Tomasz; Meyer-Roxlau, Stefanie; Piorkowski, Christopher; Tugtekin, Sems M.; Rose-John, Stefan; Yin, Xiaoke; Mayr, Manuel; Kuhlmann, Jan Dominik; Wimberger, Pauline; Grützmann, Konrad; Herzog, Natalie; Küpper, Jan-Heiner; O’Reilly, Molly; Kabir, S. Nashitha; Sommerfeld, Laura C.; Guan, Kaomei; Wielockx, Ben; Fabritz, Larissa; Nattel, Stanley; Ravens, Ursula; Dobrev, Dobromir; Wagner, Michael; El-Armouche, Ali; O'Reilly, Molly
    Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation
    In: Circulation research Jg. 129 (2021) Nr. 8, S. 804 - 820
    ISSN: 0009-7330; 1524-4571
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Gawalko, Monika; Dobrev, Dobromir
    Direct oral anticoagulation and severe obesity – One size fits all?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 37 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Gawałko, Monika; Sanders, Prashanthan; Penders, John; Li, Na; Nattel, Stanley; Dobrev, Dobromir
    Does gut microbiota affect atrial rhythm? : Causalities and speculations
    In: European heart journal Jg. 42 (2021) Nr. 35, S. 3521 - 3525
    ISSN: 1522-9645; 0195-668X
    Online Volltext: dx.doi.org/
  • Fabritz, Larissa; Crijns, Harry J. G. M.; Guasch, Eduard; Goette, Andreas; Häusler, Karl Georg; Kotecha, Dipak; Lewalter, Thorsten; Meyer, Christian; Potpara, Tatjana S.; Rienstra, Michiel; Schnabel, Renate B.; Willems, Stephan; Breithardt, Guenter; Camm, A. John; Chan, Anthony; Chua, Winnie; De Melis, Mirko; Dimopoulou, Christina; Dobrev, Dobromir; Easter, Christina; Eckardt, Lars; Haase, Doreen; Hatem, Stephane; Healey, Jeff S.; Heijman, Jordi; Hohnloser, Stefan H.; Huebner, Thomas; Ilyas, Bushra Saeed; Isaacs, Aaron; Kutschka, Ingo; Leclercq, Christophe; Lip, Gregory Y. H.; Marinelli, Elena Andreassi; Merino, Jose L.; Mont, Lluís; Nabauer, Michael; Oldgren, Jonas; Pürerfellner, Helmut; Ravens, Ursula; Savelieva, Irina; Sinner, Moritz F.; Sitch, Alice; Smolnik, Rüdiger; Steffel, Jan; Stein, Kenneth; Stoll, Monika; Svennberg, Emma; Thomas, Dierk; Van Gelder, Isabelle C.; Vardar, Burcu; Wakili, Reza; Wieloch, Mattias; Zeemering, Stef; Ziegler, Paul D.; Heidbuchel, Hein; Hindricks, Gerhard; Schotten, Ulrich; Kirchhof, Paulus
    Dynamic risk assessment to improve quality of care in patients with atrial fibrillation : The 7th AFNET/EHRA Consensus Conference
    In: EP Europace Jg. 23 (2021) Nr. 3, S. 329 - 344
    ISSN: 1532-2092; 1099-5129
    Online Volltext: dx.doi.org/ (Open Access)
  • Odening, Katja E; Gomez Laris, Ana Elisa; Dobrev, Dobromir; Fabritz, Larissa; Heinzel, Frank R; Mangoni, Matteo E; Molina, Cristina E; Sacconi, Leonardo; Smith, Godfrey; Stengl, Milan; Thomas, Dierk; Zaza, Antonio; Remme, Carol Ann; Heijman, Jordi
    ESC working group on cardiac cellular electrophysiology position paper : relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research
    In: EP Europace Jg. 23 (2021) Nr. 11, S. 1795 - 1814
    ISSN: 1532-2092; 1099-5129
    Online Volltext: dx.doi.org/ (Open Access)
  • Ravens, Ursula; Gomez, Ana M.; Heijman, Jordi; Remme, Carol Ann; Dobrev, Dobromir; Smith, Godfrey; Volders, Paul G A; Cerbai, Elisabetta; Eisner, David A.; Casadei, Barbara; Zaza, Antonio; Richard, Sylvain; Mugelli, Alessandro; Vassort, Guy; Brown, Hilary F.; Sipido, Karin R.
    Edward Carmeliet (1930-2021)-channelling scientific curiosity : a tribute from the ESC Working Group on Cardiac Cellular Electrophysiology†
    In: Cardiovascular research Jg. 117 (2021) Nr. 14, S. e171 - e173
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Qi, Xiao-Yan; Vahdati Hassani, Faezeh; Hoffmann, Dennis; Xiao, Jiening; Xiong, Feng; Villeneuve, Louis R.; Ljubojevic-Holzer, Senka; Kamler, Markus; Abu-Taha, Issam; Heijman, Jordi; Bers, Donald M.; Dobrev, Dobromir; Nattel, Stanley
    Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation
    In: Circulation Research Jg. 128 (2021) Nr. 5, S. 619 - 635
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/ (Open Access)
  • Trosclair, Krystle; Si, Man; Watts, Megan; Gautier, Nicole M.; Voigt, Niels; Traylor, James; Bitay, Miklós; Baczko, Istvan; Dobrev, Dobromir; Hamilton, Kathryn A.; Bhuiyan, Md. Shenuarin; Dominic, Paari; Glasscock, Edward
    Kv1.1 potassium channel subunit deficiency alters ventricular arrhythmia susceptibility, contractility, and repolarization
    In: Physiological Reports Jg. 9 (2021) Nr. 1,
    ISSN: 2051-817X
    Online Volltext: dx.doi.org/ (Open Access)
  • Garnier, Anne; Bork, Nadja I.; Jacquet, Eric; Zipfel, Svante; Muñoz-Guijosa, Christian; Baczkó, Istvan; Reichenspurner, Hermann; Donzeau-Gouge, Patrick; Maier, Lars S.; Dobrev, Dobromir; Girdauskas, Evaldas; Nikolaev, Viacheslav O.; Fischmeister, Rodolphe; Molina, Cristina E.
    Mapping genetic changes in the cAMP-signaling cascade in human atria
    In: Journal of Molecular and Cellular Cardiology Jg. 155 (2021) S. 10 - 20
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Scott Jr, Larry; Fender, Anke C; Saljic, Arnela; Li, Luge; Chen, Xiaohui; Wang, Xiaolei; Linz, Dominik; Lang, Jilu; Hohl, Mathias; Twomey, Darragh; Pham, Thuy T; Diaz-Lankenau, Rodrigo; Chelu, Mihail G; Kamler, Markus; Entman, Mark L; Taffet, George E; Sanders, Prashanthan; Dobrev, Dobromir; Li, Na
    NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias
    In: Cardiovascular Research Jg. 117 (2021) Nr. 7, S. 1746 - 1759
    ISSN: 0008-6363; 1755-3245
    Online Volltext: dx.doi.org/ (Open Access)
  • Gawałko, Monika; Dobrev, Dobromir
    Pericardial adipose tissue : An emerging biomarker of atrial fibrillation?
    In: International Journal of Cardiology Jg. 331 (2021) S. 122 - 123
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Aguilar, Martin; Dobrev, Dobromir; Nattel, Stanley
    Postoperative Atrial Fibrillation: Features, Mechanisms, and Clinical Management
    In: Cardiac Electrophysiology Clinics Jg. 13 (2021) Nr. 1, S. 123 - 132
    ISSN: 1877-9190; 1877-9182
    Online Volltext: dx.doi.org/
  • Campbell, Hannah; Aguilar-Sanchez, Yuriana; Quick, Ann P.; Dobrev, Dobromir; Wehrens, Xander H. T.
    SPEG: A key regulator of cardiac calcium homeostasis
    In: Cardiovascular Research Jg. 117 (2021) Nr. 10, S. 2175 - 2185
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Gawałko, Monika; Dobrev, Dobromir
    Surgery-related cardiac stress : A susceptibility test of late atrial fibrillation recurrence?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 32 (2021) S. 100693
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Wang, Xiaolei; Chen, Xiaohui; Dobrev, Dobromir; Li, Na
    The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation
    In: Pflügers Archiv: European Journal of Physiology Jg. 473 (2021) S. 389 - 405
    ISSN: 1432-2013; 0031-6768; 0365-267X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Betz, Konstanze; Knuf, Franziska; Duncker, David; Giordano, Melania; Dobrev, Dobromir; Linz, Dominik
    The impact of Twitter promotion on future citation rates : The #TweetTheJournal study
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 33 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    The virtual patient : Estimating the health utility of aspirin in simulated populations
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 36 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Nattel, Stanley; Sager, Philip T.; Hüser, Jörg; Heijman, Jordi; Dobrev, Dobromir
    Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it
    In: Cardiovascular Research Jg. 117 (2021) Nr. 7, S. 1616 - 1631
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Sutanto, Henry; Cluitmans, Matthijs J.M.; Dobrev, Dobromir; Volders, Paul G.A.; Bébarová, Markéta; Heijman, Jordi
    Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis : Insights from multiscale in silico analyses
    In: Journal of Molecular and Cellular Cardiology Jg. 146 (2020) S. 69 - 83
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Tao; Xiong, Feng; Qi, Xiao-Yan; Xiao, Jiening; Villeneuve, Louis; Abu-Taha, Issam; Dobrev, Dobromir; Huang, Congxin; Nattel, Stanley
    Altered calcium handling produces reentry-promoting action potential alternans in atrial fibrillation-remodeled hearts
    In: JCI Insight Jg. 5 (2020) Nr. 8,
    ISSN: 2379-3708
    Online Volltext: dx.doi.org/ (Open Access)
  • Berlin, Sarah; Goette, Andreas; Summo, Luciana; Lossie, Janine; Gebauer, Alexander; Al-Saady, Naab; Calo, Leonardo; Naccarelli, Gerald; Schunck, Wolf-Hagen; Fischer, Robert; Camm, A.John; Dobrev, Dobromir
    Assessment of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids, in patients with persistent atrial fibrillation : Rationale and design of the PROMISE-AF phase II study
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 29 (2020) S. 100573
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Phina Muna, Azinwi; Veleva, Tina; Molina, Cristina E.; Sutanto, Henry; Tekook, Marcel A.; Wang, Qiongling; Abu-Taha, Issam Hissam; Gorka, Marcel; Künzel, Stephan; El-Armouche, Ali; Reichenspurner, Hermann C.K.; Kamler, Markus; Nikolaev, Viacheslav O.; Ravens, Ursula; Li, Na; Nattel, Stanley; Wehrens, Xander H. T.; Dobrev, Dobromir
    Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation
    In: Circulation research: An official journal of the American Heart Association Jg. 127 (2020) Nr. 8, S. 1036 - 1055
    ISSN: 0009-7330; 1524-4571
    Online Volltext: dx.doi.org/ (Open Access)
  • Veltmann, Christian; Dobrev, Dobromir
    Berücksichtigung QTc-verlängerndes Potenzial : „Vor Einleitung einer Therapie mit Antibiotika, Antipsychotika, Antiarrhythmika soll die Gefahr einer klinisch relevanten QTc-Verlängerung geprüft werden“
    In: Der Kardiologe Jg. 14 (2020) S. 32 - 34
    ISSN: 1864-9718; 1864-9726
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Breaking bad : Higher risk of osteoporosis with vitamin K antagonists compared to direct oral anticoagulants in patients with atrial fibrillation
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 27 (2020) S. 100487
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Gawałko, Monika; Kapłon-Cieślicka, Agnieszka; Hohl, Mathias; Dobrev, Dobromir; Linz, Dominik
    COVID-19 associated atrial fibrillation : Incidence, putative mechanisms and potential clinical implications
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 30 (2020) S. 100631
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Reil, Jan-Christian; Reil, Gert-Hinrich; Kovács, Árpád; Sequeira, Vasco; Waddingham, Mark T.; Lodi, Maria; Herwig, Melissa; Ghaderi, Shahrooz; Kreusser, Michael M.; Papp, Zoltán; Voigt, Niels; Dobrev, Dobromir; Meyhöfer, Svenja; Langer, Harald F.; Maier, Lars S.; Linz, Dominik; Mügge, Andreas; Hohl, Mathias; Steendijk, Paul; Hamdani, Nazha
    CaMKII activity contributes to homeometric autoregulation of the heart : A novel mechanism for the Anrep effect
    In: Journal of Physiology (2020)
    ISSN: 1469-7793; 0022-3751
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Sutanto, Henry; Lyon, Aurore; Lumens, Joost; Schotten, Ulrich; Dobrev, Dobromir; Heijman, Jordi
    Cardiomyocyte calcium handling in health and disease : Insights from in vitro and in silico studies
    In: Progress in Biophysics and Molecular Biology Jg. 157 (2020) S. 54 - 75
    ISSN: 0079-6107; 1873-1732
    Online Volltext: dx.doi.org/ (Open Access)
  • Tomasovic, Angela; Brand, Theresa; Schanbacher, Constanze; Kramer, Sofia; Hümmert, Martin W.; Godoy, Patricio; Schmidt-Heck, Wolfgang; Nordbeck, Peter; Ludwig, Jonas; Homann, Susanne; Wiegering, Armin; Shaykhutdinov, Timur; Kratz, Christoph; Knüchel, Ruth; Müller-Hermelink, Hans-Konrad; Rosenwald, Andreas; Frey, Norbert; Eichler, Jutta; Dobrev, Dobromir; El-Armouche, Ali; Hengstler, Jan G.; Müller, Oliver J.; Hinrichs, Karsten; Cuello, Friederike; Zernecke, Alma; Lorenz, Kristina
    Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects
    In: Nature Communications Jg. 11 (2020) Nr. 1, S. 1733
    ISSN: 2041-1723
    Online Volltext: dx.doi.org/ (Open Access)
  • Siebermair, Johannes; Lehner, Sebastian; Sattler, Stefan M.; Rizas, Konstantinos D.; Beckmann, Britt-Maria; Becker, Alexander; Schiller, Julia; Metz, Corona; Zacherl, Mathias; Vonderlin, Nadine; Rassaf, Tienush; Dobrev, Dobromir; Rischpler, Christoph; Kääb, Stefan; Hacker, Marcus; Todica, Andrei; Wakili, Reza
    Left-ventricular innervation assessed by ¹²³I-SPECT/CT is associated with cardiac events in inherited arrhythmia syndromes
    In: International Journal of Cardiology (2020)
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Campbell, Hannah M.; Quick, Ann P.; Abu-Taha, Issam; Chiang, David Y.; Kramm, Carlos F.; Word, Tarah A.; Brandenburg, Sören; Hulsurkar, Mohit; Alsina, Katherina M.; Liu, Hui-Bin; Martin, Brian; Uhlenkamp, Dennis; Moore, Oliver M.; Lahiri, Satadru K.; Corradini, Eleonora; Kamler, Markus; Heck, Albert J R; Lehnart, Stephan E.; Dobrev, Dobromir; Wehrens, Xander H T
    Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation
    In: Circulation Jg. 142 (2020) Nr. 12, S. 1159 - 1172
    ISSN: 1524-4539; 0009-7322; 0065-8499
    Online Volltext: dx.doi.org/ (Open Access)
  • Kozieł, Monika; Simovic, Stefan; Pavlovic, Nikola; Nedeljkovic, Milan; Paparisto, Vilma; Music, Ljilja; Goshev, Evgenii; Dan, Anca Rodica; Manola, Sime; Kusljugic, Zumreta; Trendafilova, Elina; Dobrev, Dobromir; Dan, Gheorghe-Andrei; Lip, Gregory Y.H.; Potpara, Tatjana S.
    Management of patients with newly-diagnosed atrial fibrillation : Insights from the BALKAN-AF survey
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 26 (2020) S. 100461
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Nattel, Stanley; Heijman, Jordi; Zhou, Liping; Dobrev, Dobromir
    Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy : A Translational Perspective
    In: Circulation Research Jg. 127 (2020) Nr. 1, S. 51 - 72
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/ (Open Access)
  • Hermans, Astrid N. L.; van der Velden, Rachel M. J.; Gawalko, Monika; Verhaert, Dominique V. M.; Desteghe, Lien; Duncker, David; Manninger, Martin; Heidbuchel, Hein; Pisters, Ron; Hemels, Martin; Pison, Laurent; Sohaib, Afzal; Sultan, Arian; Steven, Daniel; Wijtvliet, Petra; Tieleman, Robert; Gupta, Dhiraj; Dobrev, Dobromir; Svennberg, Emma; Crijns, Harry J. G. M.; Pluymaekers, Nikki A. H. A.; Hendriks, Jeroen M.; Linz, Dominik
    On-demand mobile health infrastructures to allow comprehensive remote atrial fibrillation and risk factor management through teleconsultation
    In: Clinical Cardiology Jg. 43 (2020) Nr. 11, S. 1232 - 1239
    ISSN: 1932-8737; 0160-9289
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Repurposing traditional immunomodulators to target the inflammatory burden of atherosclerosis
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 28 (2020) S. 100535
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Dobrev, Dobromir
    Sleep apnea and atrial fibrillation : Update 2020
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 31 (2020) S. 100681
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir; Potpara, Tatjana S.
    Smart device-based detection of atrial fibrillation: Opportunities and challenges in the emerging world of digital health
    In: International Journal of Cardiology Jg. 302 (2020) S. 108 - 109
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Mujović, Nebojša; Dobrev, Dobromir; Marinković, Milan; Russo, Vincenzo; Potpara, Tatjana S.
    The role of amiodarone in contemporary management of complex cardiac arrhythmias
    In: Pharmacological Research Jg. 151 (2020) S. 104521
    ISSN: 1096-1186; 1043-6618
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Kleeschulte, Sonja; Stolte, Svenja; Leineweber, Katja; Kamler, Markus; Bode, Johannes; Li, Na; Dobrev, Dobromir
    Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heart
    In: Basic Research in Cardiology Jg. 115 (2020) Nr. 2, S. 10
    ISSN: 1435-1803; 0300-8428
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Barefield, David Y.; McNamara, James W.; Lynch, Thomas L.; Kuster, Diederik W.D.; Govindan, Suresh; Haar, Lauren; Wang, Yang; Taylor, Erik N.; Lorenz, John N.; Nieman, Michelle L.; Zhu, Guangshuo; Luther, Pradeep K.; Varró, Andras; Dobrev, Dobromir; Ai, Xun; Janssen, Paul M.L.; Kass, David A.; Jones, Walter Keith; Gilbert, Richard J.; Sadayappan, Sakthivel
    Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury
    In: Journal of Molecular and Cellular Cardiology Jg. 129 (2019) S. 236 - 246
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Dobrev, Dobromir
    Bayesian network analyses in atrial fibrillation – A path to better therapies?
    In: International Journal of Cardiology (IJC) Heart & Vasculature (2019)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Grandi, Eleonora; Dobrev, Dobromir; Heijman, Jordi
    Computational modeling: What does it tell us about atrial fibrillation therapy?
    In: International Journal of Cardiology Jg. 287 (2019) S. 155 - 161
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Belau, Fabian; Metzner, Katharina; Christ, Torsten; Ravens, Ursula; Schaefer, Michael; Künzel, Stephan; Li, Wener; Wettwer, Erich; Dobrev, Dobromir; El-Armouche, Ali; Kämmerer, Susanne
    DPP10 is a new regulator of Nav1.5 channels in human heart
    In: International Journal of Cardiology Jg. 284 (2019) S. 68 - 73
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Wakili, Reza; Riesinger, Lisa; Fender, Anke C.; Dobrev, Dobromir
    Double Jeopardy: Will the new trials tell us how to manage patients with atrial fibrillation and coronary artery disease?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 23 (2019) S. 100369
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Goette, Andreas; Auricchio, Angelo; Boriani, Giuseppe; Braunschweig, Frieder; Terradellas, Josep Brugada; Burri, Haran; Camm, A. John; Crijns, Harry; Dagres, Nikolaos; Deharo, Jean-Claude; Dobrev, Dobromir; Hatala, Robert; Hindricks, Gerhard; Hohnloser, Stefan H.; Leclercq, Christophe; Lewalter, Thorsten; Lip, Gregory Y. H.; Merino, Jose Luis; Mont, Lluis; Prinzen, Frits; Proclemer, Alessandro; Pürerfellner, Helmut; Savelieva, Irina; Schilling, Richard; Steffel, Jan; van Gelder, Isabelle C.; Zeppenfeld, Katja; Zupan, Igor; Heidbüchel, Hein; ESC Scientific Document Group
    EHRA White Paper : Knowledge Gaps in Arrhythmia Management-Status 2019
    In: EP Europace Jg. 21 (2019) Nr. 7, S. 993 - 994
    ISSN: 1532-2092; 1099-5129
    Online Volltext: dx.doi.org/
  • Alsina, Katherina M.; Hulsurkar, Mohit; Brandenburg, Sören; Kownatzki-Danger, Daniel; Lenz, Christof; Urlaub, Henning; Abu-Taha, Issam; Kamler, Markus; Chiang, David Y.; Lahiri, Satadru K.; Reynolds, Julia O.; Quick, Ann P.; Scott, Larry; Word, Tarah A.; Gelves, Maria D.; Heck, Albert J R; Li, Na; Dobrev, Dobromir; Lehnart, Stephan E.; Wehrens, Xander H T; Urlaub, Hennig; Scott Jr., Larry
    Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation
    In: Circulation Jg. 140 (2019) Nr. 8, S. 681 - 693
    ISSN: 1524-4539
    Online Volltext: dx.doi.org/ (Open Access)
  • Sutanto, Henry; Laudy, Lian; Clerx, Michael; Dobrev, Dobromir; Crijns, Harry J.G.M.; Heijman, Jordi
    Maastricht antiarrhythmic drug evaluator (MANTA) : A computational tool for better understanding of antiarrhythmic drugs
    In: Pharmacological Research Jg. 148 (2019)
    ISSN: 1096-1186; 1043-6618
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Baumert, Mathias; Desteghe, Lien; Kadhim, Kadhim; Vernooy, Kevin; Kalman, Jonathan M.; Dobrev, Dobromir; Arzt, Michael; Sastry, Manu; Crijns, Harry J.G.M.; Schotten, Ulrich; Cowie, Martin R.; McEvoy, R. Doug; Heidbuchel, Hein; Hendriks, Jeroen; Sanders, Prashanthan; Lau, Dennis H.
    Nightly sleep apnea severity in patients with atrial fibrillation : Potential applications of long-term sleep apnea monitoring
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 24 (2019) S. 100424
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir; Aguilar, Martin; Heijman, Jordi; Guichard, Jean-Baptiste; Nattel, Stanley
    Postoperative atrial fibrillation : mechanisms, manifestations and management
    In: Nature Reviews Cardiology Jg. 16 (2019) Nr. 7, S. 417 - 436
    ISSN: 1759-5010; 1759-5002
    Online Volltext: dx.doi.org/
  • Linz, Dominik; Elliott, Adrian D.; Hohl, Mathias; Malik, Varun; Schotten, Ulrich; Dobrev, Dobromir; Nattel, Stanley; Böhm, Michael; Floras, John; Lau, Dennis H.; Sanders, Prashanthan
    Role of autonomic nervous system in atrial fibrillation
    In: International Journal of Cardiology Jg. 287 (2019) S. 181 - 188
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Scott, Larry; Li, Na; Dobrev, Dobromir
    Role of inflammatory signaling in atrial fibrillation
    In: International Journal of Cardiology Jg. 287 (2019) S. 195 - 200
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Fender, Anke C.; Wakili, Reza; Dobrev, Dobromir
    Straight to the heart : Pleiotropic antiarrhythmic actions of oral anticoagulants
    In: Pharmacological Research Jg. 145 (2019) S. 104257
    ISSN: 1096-1186; 1043-6618
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Kaya, Elif; Siebermair, Johannes; Azizy, Obayda; Dobrev, Dobromir; Rassaf, Tienush; Wakili, Reza
    Use of pulsed electron avalanche knife (PEAK) PlasmaBlade™ in patients undergoing implantation of subcutaneous implantable cardioverter-defibrillator
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 24 (2019) S. 100390
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir; Lorenz, Kristina
    Age-dependent increase in c-Jun N-terminal kinase-2 activity : Does this help to understand Ca2+ -calmodulin-dependent protein-kinase II-mediated atrial arrhythmogenesis in human atrial fibrillation?
    In: Cardiovascular Research Jg. 114 (2018) Nr. 5, S. 641 - 642
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Dan, Gheorghe-Andrei; Dobrev, Dobromir
    Antiarrhythmic drugs for atrial fibrillation : Imminent impulses are emerging
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 21 (2018) S. 11 - 15
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Sutanto, Henry; Dobrev, Dobromir; Grandi, Eleonora; Volders, Paul G.A.; Heijman, Jordi
    Calcium-dependent regulation of potassium channels in cardiac electrophysiology : A computational study
    In: Biophysical Journal: BJ Jg. 114 (2018) Nr. 3, Supplement 1, S. 473a
    ISSN: 1542-0086; 0006-3495
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Hohl, Mathias; Dobrev, Dobromir
    Can cystatin C-based estimated glomerular filtration rate help to guide individualized risk factor modification programs?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 19 (2018) S. 100 - 101
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Chen, Gong; Chelu, Mihail G.; Dobrev, Dobromir; Li, Na
    Cardiomyocyte inflammasome signaling in cardiomyopathies and atrial fibrillation : Mechanisms and potential therapeutic implications
    In: Frontiers in Physiology Jg. 9 (2018) S. 1115
    ISSN: 1664-042X
    Online Volltext: dx.doi.org/ (Open Access)
  • Ammirati, Enrico; Dobrev, Dobromir
    Conventional Troponin-I versus high-sensitivity troponin-T : Performance and incremental prognostic value in non-ST-elevation acute myocardial infarction patients with negative CK-MB based on a real-world multicenter cohort
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 20 (2018) S. 38 - 39
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Joos, J.P.; Saadatmand, A.R.; Schnabel, C.; Viktorinová, I.; Brand, T.; Kramer, M.; Nattel, S.; Dobrev, Dobromir; Tomancak, P.; Backs, J.; Kleinbongard, Petra; Heusch, Gerd; Lorenz, Kristina; Koch, E.; Weber, S.; El-Armouche, A.
    Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila
    In: Scientific Reports Jg. 8 (2018) Nr. 1, S. 2940
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Tsuji, Yukiomi; Dobrev, Dobromir
    Electrical storm : Mechanistic and therapeutic considerations to avoid death in the survivors
    In: Journal of Thoracic Disease Jg. 10 (2018) Nr. Suppl. 33, S. S4053 - S4056
    ISSN: 2077-6624; 2072-1439
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Dobrev, Dobromir; Crijns, Harry J.G.M.
    Electrocardiographic characteristics associated with atrial fibrillation – What do they tell us?
    In: International Journal of Cardiology Jg. 266 (2018) S. 143 - 144
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Yao, Chunxia; Veleva, Tina; Scott, Larry Jr.; Cao, Shuyi; Li, Luge; Chen, Gong; Jeyabal, Prince; Pan, Xiaolu; Alsina, Katherina M.; Abu-Taha, Issam; Ghezelbash, Shokoufeh; Reynolds, Corey L.; Shen, Ying H.; LeMaire, Scott A.; Schmitz, Wilhelm; Müller, Frank U.; El-Armouche, Ali; Eissa, N. Tony; Beeton, Christine; Nattel, Stanley; Wehrens, Xander H. T.; Dobrev, Dobromir; Li, Na
    Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation
    In: Circulation Jg. 138 (2018) Nr. 20, S. 2227 - 2242
    ISSN: 0009-7322; 1524-4539
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Molina, Cristina E.; Jacquet, Eric; Ponien, Prishila; Muñoz-Guijosa, Christian; Baczkó, Istvan; Maier, Lars S; Donzeau-Gouge, Patrick; Dobrev, Dobromir; Fischmeister, Rodolphe; Garnier, Anne
    Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart
    In: Cardiovascular Research Jg. 114 (2018) Nr. 2, S. 247 - 258
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Ellinwood, Nicholas; Dobrev, Dobromir; Morotti, Stefano; Grandi, Eleonora
    In silico assessment of atrial fibrillation-selectivity of ikur inhibitors : Role of variability in disease-associated remodeling
    In: Biophysical Journal Jg. 114 (2018) Nr. 3, Suppl. 1, S. 473a - 474a
    ISSN: 0006-3495; 1542-0086
    Online Volltext: dx.doi.org/ (Open Access)
  • Kotecha, Dipak; Breithardt, Günter; Camm, A. John; Lip, Gregory Y.H.; Schotten, Ulrich; Ahlsson, Anders; Arnar, David; Atar, Dan; Auricchio, Angelo; Bax, Jeroen; Benussi, Stefano; Blomstrom-Lundqvist, Carina; Borggrefe, Martin; Boriani, Giuseppe; Brandes, Axel; Calkins, Hugh; Casadei, Barbara; Castellá, Manuel; Chua, Winnie; Crijns, Harry; Dobrev, Dobromir; Fabritz, Larissa; Feuring, Martin; Freedman, Ben; Gerth, Andrea; Goette, Andreas; Guasch, Eduard; Haase, Doreen; Hatem, Stephane; Haeusler, Karl Georg; Heidbuchel, Hein; Hendriks, Jeroen; Hunter, Craig; Kääb, Stefan; Kespohl, Stefanie; Landmesser, Ulf; Lane, Deirdre A.; Lewalter, Thorsten; Mont, Lluís; Nabauer, Michael; Nielsen, Jens C.; Oeff, Michael; Oldgren, Jonas; Oto, Ali; Pison, Laurent; Potpara, Tatjana; Ravens, Ursula; Richard-Lordereau, Isabelle; Rienstra, Michiel; Savelieva, Irina; Schnabel, Renate; Sinner, Moritz F.; Sommer, Philipp; Themistoclakis, Sakis; Van Gelder, Isabelle C.; Vardas, Panagiotis E.; Verma, Atul; Wakili, Reza; Weber, Evelyn; Werring, David; Willems, Stephan; Ziegler, André; Hindricks, Gerhard; Kirchhof, Paulus
    Integrating new approaches to atrial fibrillation management : The 6th AFNET/EHRA Consensus Conference
    In: Europace Jg. 20 (2018) Nr. 3, S. 395 - 407
    ISSN: 1532-2092; 1099-5129
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Dobrev, Dobromir
    Ion channels as part of macromolecular multiprotein complexes : Clinical significance
    In: Herzschrittmachertherapie und Elektrophysiologie Jg. 29 (2018) Nr. 1, S. 30 - 35
    ISSN: 1435-1544; 0938-7412
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir; Wehrens, Xander H. T.
    Mouse Models of Cardiac Arrhythmias
    In: Circulation Research Jg. 123 (2018) Nr. 3, S. 332 - 334
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Heijman, Jordi; Kirchner, Dorit; Kunze, Franziska; Chrétien, Eva Maria; Michel-Reher, Martina B.; Voigt, Niels; Knaut, Michael; Michel, Martin C.; Ravens, Ursula; Dobrev, Dobromir
    Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation
    In: International Journal of Cardiology Jg. 255 (2018) S. 61 - 68
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Grandi, Eleonora; Dobrev, Dobromir
    Non-ion channel therapeutics for heart failure and atrial fibrillation : Are CaMKII inhibitors ready for clinical use?
    In: Journal of Molecular and Cellular Cardiology Jg. 121 (2018) S. 300 - 303
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Yao, Chunxia; van der Sangen, Niels; Heck, Albert; Langer, Barbara; Buxton, Samuel; Dobrev, Dobromir; Alsina, Katherina; Hulsurkar, Mohit; Chiang, David; Wehrens, Xander
    Novel role of the protein phosphatase 1 regulatory subunit PPP1R3A in atrial fibrillation
    In: Journal of Molecular and Cellular Cardiology Jg. 124 (2018) S. 108
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/
  • Molina, Cristina E.; Abu-Taha, Issam H.; Wang, Qiongling; Roselló-Díez, Elena; Kamler, Marcus; Nattel, Stanley; Ravens, Ursula; Wehrens, Xander H. T.; Hove-Madsen, Leif; Heijman, Jordi; Dobrev, Dobromir
    Profibrotic, electrical, and calcium-handling remodeling of the atria in heart failure patients with and without atrial fibrillation
    In: Frontiers in Physiology Jg. 9 (2018) S. 1383
    ISSN: 1664-042X
    Online Volltext: dx.doi.org/ (Open Access)
  • Abu-Taha, Issam H.; Heijman, Jordi; Feng, Yuxi; Vettel, Christiane; Dobrev, Dobromir; Wieland, Thomas
    Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins : an update
    In: Laboratory Investigation Jg. 98 (2018) Nr. 2, S. 190 - 197
    ISSN: 0023-6837; 1530-0307
    Online Volltext: dx.doi.org/ (Open Access)
  • Sutanto, Henry; Dobrev, Dobromir; Heijman, Jordi
    Resveratrol : an effective pharmacological agent to prevent inflammation-induced atrial fibrillation?
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 391 (2018) Nr. 11, S. 1163 - 1167
    ISSN: 1432-1912; 0028-1298
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir
    Sex-specific density of ventricular SK currents : is this a general feature of SK channel function?
    In: Journal of Physiology Jg. 596 (2018) Nr. 18, S. 4287 - 4288
    ISSN: 1469-7793; 0022-3751
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Switching off the jitters : Dabigatran as a candidate approach to halt atrial fibrillation?
    In: International Journal of Cardiology Jg. 271 (2018) S. 254 - 255
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    The not-so-sweet problem of hearts aflutter : Dissecting stroke risk in atrial fibrillation with concomitant diabetes
    In: International Journal of Cardiology Jg. 268 (2018) S. 153 - 154
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Guichard, Jean-Baptiste; Dobrev, Dobromir; Nattel, Stanley
    Translational challenges in atrial fibrillation
    In: Circulation Research Jg. 122 (2018) Nr. 5, S. 752 - 773
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/ (Open Access)
  • Landstrom, Andrew P.; Dobrev, Dobromir; Wehrens, Xander H.T.
    Calcium Signaling and Cardiac Arrhythmias
    In: Circulation Research Jg. 120 (2017) Nr. 12, S. 1969 - 1993
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Dobrev, Dobromir; Wehrens, Xander H. T.
    Calcium-mediated cellular triggered activity in atrial fibrillation
    In: Journal of Physiology Jg. 595 (2017) Nr. 12, S. 4001 - 4008
    ISSN: 1469-7793; 0022-3751
    Online Volltext: dx.doi.org/
  • Neef, Stefan; Heijman, Jordi; Otte, Kristian; Dewenter, Matthias; Saadatmand, Ali R.; Meyer-Roxlau, Stefanie; Antos, Christopher L.; Backs, Johannes; Dobrev, Dobromir; Wagner, Michael; Maier, Lars S.; El-Armouche, Ali
    Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 390 (2017) Nr. 8, S. 857 - 862
    ISSN: 0028-1298; 1432-1912
    Online Volltext: dx.doi.org/
  • Nattel, Stanley; Dobrev, Dobromir
    Controversies about Atrial Fibrillation Mechanisms : Aiming for Order in Chaos and Whether it Matters
    In: Circulation Research Jg. 120 (2017) Nr. 9, S. 1396 - 1398
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/ (Open Access)
  • Meyer-Roxlau, Stefanie; Lämmle, Simon; Opitz, Annett; Künzel, Stephan; Joos, Julius P.; Neef, Stefan; Sekeres, Karolina; Sosalla, Samuel T.; Schöndube, Friedrich; Alexiou, Konstantin; Maier, Lars S.; Dobrev, Dobromir; Guan, Kaomei; Weber, Silvio; El-Armouche, Ali
    Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation
    In: Basic Research in Cardiology Jg. 112 (2017) Nr. 4,
    ISSN: 0300-8428; 1435-1803
    Online Volltext: dx.doi.org/
  • Goette, Andreas; Kalman, Jonathan M.; Aguinaga, Luis; Akar, Joseph; Cabrera, Jose Angel; Chen, Shih Ann; Chugh, Sumeet S.; Corradi, Domenico; D'Avila, Andre; Dobrev, Dobromir; Fenelon, Guilherme; Gonzalez, Mario; Hatem, Stephane N.; Helm, Robert; Hindricks, Gerhard; Ho, Siew Yen; Hoit, Brian; Jalife, Jose; Kim, Young-Hoon; Lip, Gregory Y.H.; Ma, Chang-Sheng; Marcus, Gregory M.; Murray, Katherine; Nogami, Akihiko; Sanders, Prashanthan; Uribe, William; Van Wagoner, David R.; Nattel, Stanley
    EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies : definition, characterization, and clinical implication
    In: Heart Rhythm Jg. 14 (2017) Nr. 1, S. e3 - e40
    ISSN: 1547-5271; 1556-3871
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Veleva, Tina; Scott, Larry; Dobrev, Dobromir; Li, Na; Wehrens, Xander H.T.; Müller, Frank U.; Yao, Chunxia; Nattel, Stanley
    Enhanced Activation of Inflammasome Promotes Atrial Fibrillation
    In: Journal of Molecular and Cellular Cardiology Jg. 112 (2017) S. 147
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/
  • Ellinwood, Nicholas; Dobrev, Dobromir; Morotti, Stefano; Grandi, Eleonora
    Erratum to: "Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity"
    In: Chaos Jg. 27 (2017) Nr. 10,
    ISSN: 1089-7682
    Online Volltext: dx.doi.org/
  • Meyer-Roxlau, Stefanie; Lämmle, Simon; Opitz, Annett; Künzel, Stephan; Joos, Julius P.; Neef, Stefan; Sekeres, Karolina; Sossalla, Samuel; Schöndube, Friedrich; Alexiou, Konstantin; Maier, Lars S.; Dobrev, Dobromir; Guan, Kaomei; Weber, Silvio; El-Armouche, Ali
    Erratum to: Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation
    In: Basic Research in Cardiology Jg. 112 (2017) Nr. 5,
    ISSN: 0300-8428; 0300-8428
    Online Volltext: dx.doi.org/
  • Ellinwood, Nicholas; Dobrev, Dobromir; Morotti, Stefano; Grandi, Eleonora
    In silico assessment of efficacy and safety of Ikur inhibitors in chronic atrial fibrillation : Role of kinetics and state-dependence of drug binding
    In: Frontiers in Pharmacology Jg. 8 (2017) Nr. NOV, S. 799
    ISSN: 1663-9812
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Dobrev, Dobromir
    Inhibition of small-conductance Ca²⁺-Activated K⁺ channels : The long-Awaited breakthrough for antiarrhythmic drug therapy of atrial fibrillation?
    In: Circulation: Arrhythmia and Electrophysiology Jg. 10 (2017) Nr. 10, S. e005776
    ISSN: 1941-3149; 1941-3084
    Online Volltext: dx.doi.org/
  • Schmidt, Constanze; Wiedmann, Felix; Zhou, Xiao-Bo; Heijman, Jordi; Voigt, Niels; Ratte, Antonius; Lang, Siegfried; Kallenberger, Stefan M.; Campana, Chiara; Weymann, Alexander; De Simone, Raffaele; Szabo, Gabor; Ruhparwar, Arjang; Kallenbach, Klaus; Karck, Matthias; Ehrlich, Joachim R.; Baczkó, István; Borggrefe, Martin; Ravens, Ursula; Dobrev, Dobromir; Katus, Hugo A.; Thomas, Dierk
    Inverse remodelling of K2P 3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation : Implications for patient-specific antiarrhythmic drug therapy
    In: European Heart Journal Jg. 38 (2017) Nr. 22, S. 1764 - 1774
    ISSN: 0195-668X; 1522-9645
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  • Heijman, Jordi; Ghezelbash, Shokoufeh; Dobrev, Dobromir
    Investigational antiarrhythmic agents : promising drugs in early clinical development
    In: Expert Opinion on Investigational Drugs Jg. 26 (2017) Nr. 8, S. 897 - 907
    ISSN: 1744-7658; 1354-3784
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  • Chen, Yu; Surinkaew, Sirirat; Naud, Patrice; Qi, Xiao-Yan; Gillis, Marc-Antoine; Shi, Yan-Fen; Tardif, Jean-Claude; Dobrev, Dobromir; Nattel, Stanley
    JAK-STAT signalling and the atrial fibrillation promoting fibrotic substrate
    In: Cardiovascular Research Jg. 113 (2017) Nr. 3, S. 310 - 320
    ISSN: 0008-6363; 1755-3245
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  • Wakili, Reza; Dobrev, Dobromir
    Late-breaking trials : Atrial fibrillation
    In: Dialogues in Cardiovascular Medicine Jg. 22 (2017) Nr. 3, S. 42 - 43
    ISSN: 1272-9949
  • Abu-Taha, Issam H; Heijman, Jordi; Hippe, Hans-Jörg; Wolf, Nadine M; El-Armouche, Ali; Nikolaev, Viacheslav O; Schäfer, Marina; Würtz, Christina M; Neef, Stefan; Voigt, Niels; Baczkó, István; Varró, András; Müller, Marion; Meder, Benjamin; Katus, Hugo A; Spiger, Katharina; Vettel, Christiane; Lehmann, Lorenz H; Backs, Johannes; Skolnik, Edward Y; Lutz, Susanne; Dobrev, Dobromir; Wieland, Thomas
    Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure
    In: Circulation Jg. 135 (2017) Nr. 9, S. 881 - 897
    ISSN: 0009-7322; 1524-4539
  • Abu-Taha, Issam H.; Heijman, Jordi; Hippe, Hans-Jörg; Wolf, Nadine M.; El-Armouche, Ali; Nikolaev, Viacheslav O.; Schäfer, Marina; Würtz, Christina M.; Neef, Stefan; Voigt, Niels; Baczkó, István; Varró, András; Müller, Marion; Meder, Benjamin; Katus, Hugo A.; Spiger, Katharina; Vettel, Christiane; Lehmann, Lorenz H.; Backs, Johannes; Skolnik, Edward Y.; Lutz, Susanne; Dobrev, Dobromir; Wieland, Thomas
    Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure
    In: Circulation Jg. 135 (2017) Nr. 9, S. 881 - 897
    ISSN: 1524-4539; 0009-7322
    Online Volltext: dx.doi.org/ (Open Access)
  • Chiamvimonvat, Nipavan; Chen-Izu, Ye; Clancy, Colleen E.; Deschenes, Isabelle; Dobrev, Dobromir; Heijman, Jordi; Izu, Leighton; Qu, Zhilin; Ripplinger, Crystal M.; Vandenberg, Jamie I.; Weiss, James N.; Koren, Gideon; Banyasz, Tamas; Grandi, Eleonora; Sanguinetti, Michael C.; Bers, Donald M.; Nerbonne, Jeanne M.
    Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics
    In: Journal of Physiology Jg. 595 (2017) Nr. 7, S. 2229 - 2252
    ISSN: 1469-7793; 0022-3751
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  • Wakili, Reza; Dobrev, Dobromir
    Response to: “The emerging role of hybrid ablation for ablation” by Spartialis M. et al.
    In: International Journal of Cardiology Jg. 249 (2017) S. 258
    ISSN: 0167-5273; 1874-1754
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  • Ellinwood, Nicholas; Dobrev, Dobromir; Morotti, Stefano; Grandi, Eleonora
    Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity
    In: Chaos Jg. 27 (2017) Nr. 9, art. no. 093918
    ISSN: 1054-1500; 1089-7682
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Ghezelbash, Shokoufeh; Wehrens, Xander H.T.; Dobrev, Dobromir
    Serine/Threonine Phosphatases in Atrial Fibrillation
    In: Journal of Molecular and Cellular Cardiology Jg. 103 (2017) S. 110 - 120
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ji, Yuan; Varkevisser, Rosanne; Opacic, Dragan; Bossu, Alexandre; Kuiper, Marion; Beekman, Jet D M; Yang, Sihyung; Khan, Azinwi Phina; Dobrev, Dobromir; Voigt, Niels; Wang, Michael Zhuo; Verheule, Sander; Vos, Marc A; van der Heyden, Marcel A G
    The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models
    In: British Journal of Pharmacology (BJP) Jg. 174 (2017) Nr. 15, S. 2576 - 2590
    ISSN: 0007-1188; 1476-5381; 0366-0826
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  • Kirchhof, Paulus; Benussi, Stefano; Kotecha, Dipak; Ahlsson, Anders; Atar, Dan; Casadei, Barbara; Castella, Manuel; Diener, Hans Christoph; Heidbuchel, Hein; Hendriks, Jeroen; Hindricks, Gerhard; Manolis, Antonis S; Oldgren, Jonas; Popescu, Bogdan Alexandru; Schotten, Ulrich; Van Putte, Bart; Vardas, Panagiotis; Agewall, Stefan; Camm, John; Baron Esquivias, Gonzalo; Budts, Werner; Carerj, Scipione; Casselman, Filip; Coca, Antonio; De Caterina, Raffaele; Deftereos, Spiridon; Dobrev, Dobromir; Ferro, José M; Filippatos, Gerasimos; Fitzsimons, Donna; Gorenek, Bulent; Guenoun, Maxine; Hohnloser, Stefan H; Kolh, Philippe; Lip, Gregory Y H; Manolis, Athanasios; McMurray, John; Ponikowski, Piotr; Rosenhek, Raphael; Ruschitzka, Frank; Savelieva, Irina; Sharma, Sanjay; Suwalski, Piotr; Tamargo, Juan Luis; Taylor, Clare J; Van Gelder, Isabelle C; Voors, Adriaan A; Windecker, Stephan; Zamorano, Jose Luis; Zeppenfeld, Katja
    2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
    In: Europace Jg. 18 (2016) Nr. 11, S. 1609 - 1678
    ISSN: 1099-5129; 1532-2092
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  • Kirchhof, Paulus; Benussi, Stefano; Kotecha, Dipak; Ahlsson, Anders; Atar, Dan; Casadei, Barbara; Castella, Manuel; Diener, Hans Christoph; Heidbuchel, Hein; Hendriks, Jeroen; Hindricks, Gerhard; Manolis, Antonis S; Oldgren, Jonas; Popescu, Bogdan Alexandru; Schotten, Ulrich; Van Putte, Bart; Vardas, Panagiotis; Agewall, Stefan; Camm, John; Baron Esquivias, Gonzalo; Budts, Werner; Carerj, Scipione; Casselman, Filip; Coca, Antonio; De Caterina, Raffaele; Deftereos, Spiridon; Dobrev, Dobromir; Ferro, José M; Filippatos, Gerasimos; Fitzsimons, Donna; Gorenek, Bulent; Guenoun, Maxine; Hohnloser, Stefan H; Kolh, Philippe; Lip, Gregory Y H; Manolis, Athanasios; McMurray, John; Ponikowski, Piotr; Rosenhek, Raphael; Ruschitzka, Frank; Savelieva, Irina; Sharma, Sanjay; Suwalski, Piotr; Tamargo, Juan Luis; Taylor, Clare J; Van Gelder, Isabelle C; Voors, Adriaan A; Windecker, Stephan; Zamorano, Jose Luis; Zeppenfeld, Katja
    2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
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    Online Volltext: dx.doi.org/
  • Kirchhof, Paulus; Benussi, Stefano; Kotecha, Dipak; Ahlsson, Anders; Atar, Dan; Casadei, Barbara; Castella, Manuel; Diener, Hans Christoph; Heidbuchel, Hein; Hendriks, Jeroen; Hindricks, Gerhard; Manolis, Antonis S; Oldgren, Jonas; Popescu, Bogdan Alexandru; Schotten, Ulrich; Van Putte, Bart; Vardas, Panagiotis; Agewall, Stefan; Camm, John; Baron Esquivias, Gonzalo; Budts, Werner; Carerj, Scipione; Casselman, Filip; Coca, Antonio; De Caterina, Raffaele; Deftereos, Spiridon; Dobrev, Dobromir; Ferro, José M; Filippatos, Gerasimos; Fitzsimons, Donna; Gorenek, Bulent; Guenoun, Maxine; Hohnloser, Stefan H; Kolh, Philippe; Lip, Gregory Y H; Manolis, Athanasios; McMurray, John; Ponikowski, Piotr; Rosenhek, Raphael; Ruschitzka, Frank; Savelieva, Irina; Sharma, Sanjay; Suwalski, Piotr; Tamargo, Juan Luis; Taylor, Clare J; Van Gelder, Isabelle C; Voors, Adriaan A; Windecker, Stephan; Zamorano, Jose Luis; Zeppenfeld, Katja
    2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
    In: European Journal of Cardio-Thoracic Surgery Jg. 50 (2016) Nr. 5, S. e1 - e88
    ISSN: 1873-734X; 1010-7940; 1567-4258; 1878-3309
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  • Kirchhof, Paulus; Breithardt, Günter; Bax, Jeroen; Benninger, Gerlinde; Blomstrom-Lundqvist, Carina; Boriani, Giuseppe; Brandes, Axel; Brown, Helen; Brueckmann, Martina; Calkins, Hugh; Calvert, Melanie; Christoffels, Vincent; Crijns, Harry; Dobrev, Dobromir; Ellinor, Patrick; Fabritz, Larissa; Fetsch, Thomas; Freedman, S. Ben; Gerth, Andrea; Goette, Andreas; Guasch, Eduard; Hack, Guido; Haegeli, Laurent; Hatem, Stephane; Haeusler, Karl Georg; Heidbüchel, Hein; Heinrich-Nols, Jutta; Hidden-Lucet, Francoise; Hindricks, Gerd; Juul-Möller, Steen; Kääb, Stefan; Kappenberger, Lukas; Kespohl, Stefanie; Kotecha, Dipak; Lane, Deirdre A.; Leute, Angelika; Lewalter, Thorsten; Meyer, Ralf; Mont, Lluis; Münzel, Felix; Nabauer, Michael; Nielsen, Jens C.; Oeff, Michael; Oldgren, Jonas; Oto, Ali; Piccini, Jonathan P.; Pilmeyer, Art; Potpara, Tatjana; Ravens, Ursula; Reinecke, Holger; Rostock, Thomas; Rustige, Joerg; Savelieva, Irene; Schnabel, Renate; Schotten, Ulrich; Schwichtenberg, Lars; Sinner, Moritz F.; Steinbeck, Gerhard; Stoll, Monika; Tavazzi, Luigi; Themistoclakis, Sakis; Tse, Hung Fat; van Gelder, Isabelle C.; Vardas, Panagiotis E.; Varpula, Timo; Vincent, Alphons; Werring, David; Willems, Stephan; Ziegler, André; Lip, Gregory Y. H.; Camm, A. John
    A roadmap to improve the quality of atrial fibrillation managementconference : proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus
    In: Europace Jg. 18 (2016) Nr. 1, S. 37 - 50
    ISSN: 1532-2092; 1099-5129
    Online Volltext: dx.doi.org/ (Open Access)
  • Ferrari, R.; Bertini, Matteo; Blomstrom-Lundqvist, Carina; Dobrev, Dobromir; Kirchhof, Paulus; Pappone, Carlo; Ravens, Ursula; Tamargo, Juan Luis; Tavazzi, Luigi; Vicedomini, Gabriele G.
    An update on atrial fibrillation in 2014 : From pathophysiology to treatment
    In: International Journal of Cardiology Jg. 203 (2016) S. 22 - 29
    ISSN: 1874-1754; 0167-5273
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  • Voigt, Niels; Dobrev, Dobromir
    Atrial-Selective Potassium Channel Blockers
    In: Cardiac Electrophysiology Clinics Jg. 8 (2016) Nr. 2, S. 411 - 421
    ISSN: 1877-9190; 1877-9182
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir
    Challenges to the translation of basic science findings to atrial fibrillation therapies
    In: Future Cardiology Jg. 12 (2016) Nr. 3, S. 251 - 254
    ISSN: 1479-6678
    Online Volltext: dx.doi.org/
  • Yan Qi, Xiao; Nattel, Stanley; Dobrev, Dobromir; Heijman, Jordi
    Computational Analysis of Heart-Failure-Related Remodeling of Cytosolic and Nuclear Calcium Handling in the Canine Atrial Cardiomyocyte
    In: Biophysical Journal Jg. 110 (2016) Nr. 3, Suppl.1, S. 435a
    ISSN: 0006-3495; 1542-0086
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Erfanian Abdoust, Pegah; Voigt, Niels; Nattel, Stanley; Dobrev, Dobromir
    Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation
    In: The Journal of Physiology Jg. 594 (2016) Nr. 3, S. 537 - 553
    ISSN: 0022-3751; 1469-7793
    Online Volltext: dx.doi.org/
  • Schotten, U; Dobrev, Dobromir; Platonov, P G; Kottkamp, H; Hindricks, G
    Current controversies in determining the main mechanisms of atrial fibrillation
    In: Journal of Internal Medicine Jg. 279 (2016) Nr. 5, S. 428 - 438
    ISSN: 0954-6820; 1365-2796
    Online Volltext: dx.doi.org/
  • Nattel, Stanley; Dobrev, Dobromir
    Deciphering the fundamental mechanisms of atrial fibrillation : a quest for over a century
    In: Cardiovascular Research Jg. 109 (2016) Nr. 4, S. 465 - 466
    ISSN: 1755-3245
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir; Molina, Cristina E
    Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis
    In: Arrhythmia & Electrophysiology Review Jg. 5 (2016) Nr. 1, S. 14 - 19
    ISSN: 2050-3377
    Online Volltext: dx.doi.org/ (Open Access)
  • Smith, Sakima A; Hughes, Langston D; Kline, Crystal F; Kempton, Amber N; Dorn, Lisa E; Curran, Jerry; Makara, Michael; Webb, Tyler R; Wright, Patrick; Voigt, Niels; Binkley, Philip F; Janssen, Paul M L; Kilic, Ahmet; Carnes, Cynthia A; Dobrev, Dobromir; Rasband, Matthew N; Hund, Thomas J; Mohler, Peter J
    Dysfunction of the β2-spectrin-based pathway in human heart failure
    In: American Journal of Physiology: Heart and Circulatory Physiology Jg. 310 (2016) Nr. 11, S. H1583 - H1591
    ISSN: 0363-6135; 1522-1539
    Online Volltext: dx.doi.org/ (Open Access)
  • Goette, Andreas; Kalman, Jonathan M.; Aguinaga, Luis; Akar, Joseph; Cabrera, Jose Angel; Chen, Shih Ann; Chugh, Sumeet S.; Corradi, Domenico; D׳Avila, Andre; Dobrev, Dobromir; Fenelon, Guilherme; Gonzalez, Mario; Hatem, Stephane N.; Helm, Robert; Hindricks, Gerhard; Ho, Siew Yen; Hoit, Brian; Jalife, Jose; Kim, Young-Hoon; Lip, Gregory Y.H.; Ma, Chang-Sheng; Marcus, Gregory M.; Murray, Katherine; Nogami, Akihiko; Sanders, Prashanthan; Uribe, William; Van Wagoner, David R.; Nattel, Stanley
    EHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: : definition, characterisation, and clinical implication
    In: Journal of Arrhythmia Jg. 32 (2016) Nr. 4, S. 247 - 278
    ISSN: 1880-4276
    Online Volltext: dx.doi.org/ (Open Access)
  • Goette, Andreas; Kalman, Jonathan M; Aguinaga, Luis; Akar, Joseph; Cabrera, Jose Angel; Chen, Shih Ann; Chugh, Sumeet S; Corradi, Domenico; D'Avila, Andre; Dobrev, Dobromir; Fenelon, Guilherme; Gonzalez, Mario; Hatem, Stephane N; Helm, Robert; Hindricks, Gerhard; Ho, Siew Yen; Hoit, Brian; Jalife, Jose; Kim, Young-Hoon; Lip, Gregory Y H; Ma, Chang-Sheng; Marcus, Gregory M; Murray, Katherine; Nogami, Akihiko; Sanders, Prashanthan; Uribe, William; Van Wagoner, David R; Nattel, Stanley; Centurion, Osmar A; Kuck, Karl-Heinz; Patton, Kristen K; Sapp, John L; Stiles, Martin; Svendsen, Jesper Hastrup; Upadhyay, Gaurav A; Shantsila, Alena
    EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies : definition, characterization, and clinical implication
    In: Europace Jg. 18 (2016) Nr. 10, S. 1455 - 1490
    ISSN: 1099-5129; 1532-2092
    Online Volltext: dx.doi.org/
  • Nattel, Stanley; Dobrev, Dobromir
    Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation
    In: Nature Reviews Cardiology Jg. 13 (2016) Nr. 10, S. 575 - 590
    ISSN: 1759-5010; 1759-5002
    Online Volltext: dx.doi.org/
  • Na, Li; Wehrens, Xander Ht T; Dobrev, Dobromir
    PITX2 : a master regulator of cardiac channelopathy in atrial fibrillation?
    In: Cardiovascular Research Jg. 109 (2016) Nr. 3, S. 345 - 347
    ISSN: 1755-3245
    Online Volltext: dx.doi.org/
  • Chiang, David Y; Heck, Albert J R; Dobrev, Dobromir; Wehrens, Xander H T
    Regulating the regulator : Insights into the cardiac protein phosphatase 1 interactome
    In: Journal of Molecular and Cellular Cardiology Jg. 101 (2016) S. 165 - 172
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schmidt, Constanze; Wiedmann, Felix; Voigt, Niels; Zhou, Xiao-Bo; Heijman, Jordi; Lang, Siegfried; Albert, Virginia; Kallenberger, Stefan; Ruhparwar, Arjang; Szabó, Gábor; Kallenbach, Klaus; Karck, Matthias; Borggrefe, Martin; Biliczki, Peter; Ehrlich, Joachim R; Baczkó, István; Lugenbiel, Patrick; Schweizer, Patrick A; Donner, Birgit C; Katus, Hugo A; Dobrev, Dobromir; Thomas, Dierk
    Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"
    In: Circulation Jg. 133 (2016) Nr. 11, S. e440 - 441
    ISSN: 0009-7322; 1524-4539
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Stathopoulou, Konstantina; Cuello, Friederike; Eaton, Philip; Carrier, Lucie; Eschenhagen, Thomas; Sadayappan, Sakthivel; Dobrev, Dobromir; Voigt, Niels; Wijnker, Paul J. M.; Schröder, Ewald; Donzelli, Sonia; Buck, Friedrich; van der Velden, Jolanda; Diering, Simon; Richter, Florian; Piasecki, Angelika; Heidler, Juliana; Wittig, Ilka
    S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure
    In: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 Jg. 30 (2016) Nr. 5, S. 1849 - 1864
    ISSN: 0892-6638; 0892-6638
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Hartmann, Nico; Mason, Fleur E; Braun, Inga; Pabel, Steffen; Voigt, Niels; Schotola, Hanna; Fischer, Thomas H; Dobrev, Dobromir; Danner, Bernhard C; Renner, André; Gummert, Jan; Belardinelli, Luiz; Frey, Norbert; Maier, Lars S; Hasenfuss, Gerd; Sossalla, Samuel
    The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology
    In: Journal of Molecular and Cellular Cardiology Jg. 94 (2016) S. 95 - 106
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Schirmer, Ilona; Dobrev, Dobromir
    The multiple proarrhythmic roles of cardiac calcium-handling abnormalities : triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling
    In: Europace Jg. 18 (2016) Nr. 10, S. 1452 - 1454
    ISSN: 1099-5129; 1532-2092
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Nattel, Stanley; Dobrev, Dobromir; Wehrens, Xander H.T.; Melka, Jonathan; Algalarrando, Vincent
    The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation : a critical analysis
    In: Cardiovascular Research Jg. 109 (2016) Nr. 4, S. 467 - 479
    ISSN: 1755-3245
    Online Volltext: dx.doi.org/
  • Priori, Silvia G; Blomström-Lundqvist, Carina; Mazzanti, Andrea; Blom, Nico; Borggrefe, Martin; Camm, John; Elliott, Perry Mark; Fitzsimons, Donna; Hatala, Robert; Hindricks, Gerhard; Kirchhof, Paulus; Kjeldsen, Keld; Kuck, Karl-Heinz; Hernandez-Madrid, Antonio; Nikolaou, Nikolaos; Norekvål, Tone M; Spaulding, Christian; Van Veldhuisen, Dirk J; Kolh, Philippe; Lip, Gregory Y H; Agewall, Stefan; Barón-Esquivias, Gonzalo; Boriani, Giuseppe; Budts, Werner; Bueno, Héctor; Capodanno, Davide; Carerj, Scipione; Crespo-Leiro, Maria G; Czerny, Martin; Deaton, Christi; Dobrev, Dobromir; Erol, Çetin; Galderisi, Maurizio; Gorenek, Bulent; Kriebel, Thomas; Lambiase, Pier; Lancellotti, Patrizio; Lane, Deirdre A; Lang, Irene; Manolis, Athanasios J; Morais, Joao; Moreno, Javier; Piepoli, Massimo F; Rutten, Frans H; Sredniawa, Beata; Zamorano, Jose L; Zannad, Faiez
    2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death : The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the Europe
    In: Europace Jg. 17 (2015) Nr. 11, S. 1601 - 1687
    ISSN: 1099-5129; 1532-2092
    Online Volltext: dx.doi.org/
  • Chiang, David Y.; Lebesgue, Nicolas; Beavers, David L.; Alsina, Katherina M.; Damen, J. Mirjam A.; Voigt, Niels; Dobrev, Dobromir; Wehrens, Xander H.T.; Scholten, Arjen
    Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients
    In: Journal of the American College of Cardiology Jg. 65 (2015) Nr. 2, S. 163 - 173
    ISSN: 0735-1097
    Online Volltext: dx.doi.org/ (Open Access)
  • Ghezelbash, Shokoufeh; Molina, Cristina E; Dobrev, Dobromir
    Altered atrial metabolism : an underappreciated contributor to the initiation and progression of atrial fibrillation
    In: Journal of the American Heart Association Jg. 4 (2015) Nr. 3, S. e001808
    ISSN: 2047-9980
    Online Volltext: dx.doi.org/ (Open Access)
  • Ravens, Ursula; Katircioglu-Öztürk, Deniz; Wettwer, Erich; Christ, Torsten; Dobrev, Dobromir; Voigt, Niels; Poulet, Claire; Loose, Simone; Simon, Jana; Stein, Agnes; Matschke, Klaus E.; Knaut, Michael A.; Oto, Emre; Oto, Ali; Güvenir, Halil A.
    Application of the RIMARC algorithm to a large data set of action potentials and clinical parameters for risk prediction of atrial fibrillation
    In: Medical and Biological Engineering and Computing Jg. 53 (2015) Nr. 3, S. 263 - 273
    ISSN: 0140-0118; 1741-0444
    Online Volltext: dx.doi.org/ (Open Access)
  • Harada, Masahide; Tadevosyan, Artavazd; Qi, Xiaoyan; Xiao, Jiening; Liu, Tao; Voigt, Niels; Karck, Matthias; Kamler, Markus; Kodama, Itsuo; Murohara, Toyoaki; Dobrev, Dobromir; Nattel, Stanley
    Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium Handling : Potential Role in Metabolic Adaptation and Prevention of Progression
    In: Journal of the American College of Cardiology Jg. 66 (2015) Nr. 1, S. 47 - 58
    ISSN: 0735-1097
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Voigt, Niels; Ghezelbash, Shokoufeh; Schirmer, Ilona; Dobrev, Dobromir
    Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics : How Close to Clinical Implementation?
    In: Journal of Cardiovascular Pharmacology Jg. 66 (2015) Nr. 6, S. 515 - 522
    ISSN: 0160-2446
    Online Volltext: dx.doi.org/
  • Weber, Silvio; Meyer-Roxlau, Stefanie; Wagner, Michael; Dobrev, Dobromir; El-Armouche, Ali
    Counteracting Protein Kinase Activity in the Heart : The Multiple Roles of Protein Phosphatases
    In: Fronitiers ind Pharmacology Jg. 6 (2015) S. 270
    ISSN: 1663-9812
    Online Volltext: dx.doi.org/ (Open Access)
  • Smith, Sakima A; Sturm, Amy C; Curran, Jerry; Kline, Crystal F; Little, Sean C; Bonilla, Ingrid M; Long, Victor P; Makara, Michael; Polina, Iuliia; Hughes, Langston D; Webb, Tyler R; Wei, Zhiyi; Wright, Patrick; Voigt, Niels; Bhakta, Deepak; Spoonamore, Katherine G; Zhang, Chuansheng; Weiss, Raul; Binkley, Philip F; Janssen, Paul M; Kilic, Ahmet; Higgins, Robert S; Sun, Mingzhai; Ma, Jianjie; Dobrev, Dobromir; Zhang, Mingjie; Carnes, Cynthia A; Vatta, Matteo; Rasband, Matthew N; Hund, Thomas J; Mohler, Peter J
    Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia
    In: Circulation Jg. 131 (2015) Nr. 8, S. 695 - 708
    ISSN: 0009-7322; 1524-4539
    Online Volltext: dx.doi.org/ (Open Access)
  • Glasscock, Edward; Voigt, Niels; McCauley, Mark D.; Sun, Qiang; Li, Na; Chiang, David Y.; Zhou, Xiao-Bo; Molina, Cristina E.; Thomas, Dierk; Schmidt, Constanze; Skapura, Darlene G.; Noebels, Jeffrey L.; Dobrev, Dobromir; Wehrens, Xander H. T.
    Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation
    In: Basic Research in Cardiology Jg. 110 (2015) Nr. 5, S. 47
    ISSN: 1435-1803; 0300-8428
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Qi, Xiao-Yan; Huang, Hai; Ordog, Balazs; Luo, Xiaobin; Naud, Patrice; Sun, Yiguo; Wu, Chia-Tung; Dawson, Kristin; Tadevosyan, Artavazd; Chen, Yu; Harada, Masahide; Dobrev, Dobromir; Nattel, Stanley
    Fibroblast inward-rectifier potassium current upregulation in profibrillatory atrial Remodeling
    In: Circulation Research Jg. 116 (2015) Nr. 5, S. 836 - 845
    ISSN: 1524-4571; 0009-7330
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  • Chiang, David Y; Zhang, Min; Voigt, Niels; Alsina, Katherina M; Jakob, Heinz G.; Martin, James F; Dobrev, Dobromir; Wehrens, Xander H T; Li, Na
    Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation
    In: International Journal of Cardiology Jg. 184 (2015) S. 190 - 197
    ISSN: 0167-5273
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Nattel, Stanley; Dobrev, Dobromir
    Innovative therapeutics for atrial fibrillation : Imminent breakthroughs or much ado about nothing?
    In: Journal of Cardiovascular Pharmacology Jg. 66 (2015) Nr. 5, S. 409 - 411
    ISSN: 0160-2446
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir
    Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation
    In: Basic Research in Cardiology Jg. 110 (2015) S. 41
    ISSN: 0300-8428; 1435-1803
    Online Volltext: dx.doi.org/
  • Quang, Khai Le; Maguy, Ange; Qi, Xiao-Yan; Naud, Patrice; Xiong, Feng; Tadevosyan, Artavazd; Shi, Yan-Fen; Chartier, Denis; Tardif, Jean-Claude; Dobrev, Dobromir; Nattel, Stanley
    Loss of Cardiomyocyte Integrin-Linked Kinase Produces an Arrhythmogenic Cardiomyopathy in Mice
    In: Circulation: Arrhythmia and Electrophysiology Jg. 8 (2015) Nr. 4, S. 921 - 932
    ISSN: 1941-3149; 1941-3084
    Online Volltext: dx.doi.org/ (Open Access)
  • Voigt, Niels; Pearman, Charles M.; Dobrev, Dobromir; Dibb, Katharine M.
    Methods for isolating atrial cells from large mammals and humans
    In: Journal of Molecular and Cellular Cardiology Jg. 86 (2015) S. 187 - 198
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/ (Open Access)
  • Voigt, Niels; Heijman, Jordi; Dobrev, Dobromir
    New antiarrhythmic targets in atrial fibrillation
    In: Future cardiology Jg. 11 (2015) Nr. 6, S. 645 - 654
    ISSN: 1744-8298; 1479-6678
    Online Volltext: dx.doi.org/
  • Zhou, Xiao-Bo; Feng, Yu-Xi; Sun, Qiang; Lukowski, Robert; Qiu, Yi; Spiger, Katharina; Li, Zhai; Ruth, Peter; Korth, Michael; Skolnik, Edward Y.; Borggrefe, Martin; Dobrev, Dobromir; Wieland, Thomas
    Nucleoside Diphosphate Kinase B–Activated Intermediate Conductance Potassium Channels Are Critical for Neointima Formation in Mouse Carotid Arteries
    In: Arteriosclerosis, Thrombosis, and Vascular Biology Jg. 35 (2015) Nr. 8, S. 1852 - 1861
    ISSN: 1079-5642; 1524-4636
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  • Schotten, Ulrich; Hatem, Stéphane Nicolas; Ravens, Ursula; Jaïs, Pïerre; Müller, Frank Ulrich; Goette, Andres; Rohr, Stephan; Antoons, Gudrun; Pieske, Burkert Mathias; Scherr, Daniel; Oto, Ali; Casadei, Barbara; Verheule, Sander; Cartlidge, David; Steinmeyer, Klaus; Götsche, Thorsten; Dobrev, Dobromir; Kockskämper, Jens; Lendeckel, Uwe; Fabritz, Larissa; Kirchhof, Paulus F.
    The European Network for Translational Research in Atrial Fibrillation (EUTRAF) : Objectives and initial results
    In: Eurospace Jg. 17 (2015) Nr. 10, S. 1457 - 1466
    ISSN: 1099-5129
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Heusch, Gerd; Dobrev, Dobromir
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    In: Cardiology Jg. 132 (2015) S. 45 - 48
    ISSN: 0008-6312; 1421-9751
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  • Schmidt, Constanze; Wiedmann, Felix; Voigt, Niels; Zhou, Xiao-Bo; Heijman, Jordi; Lang, Siegfried; Albert, Virginia; Kallenberger, Stefan; Ruhparwar, Arjang; Szabó, Gábor; Kallenbach, Klaus; Karck, Matthias; Borggrefe, Martin; Biliczki, Peter; Ehrlich, Joachim R; Baczkó, István; Lugenbiel, Patrick; Schweizer, Patrick A; Donner, Birgit C; Katus, Hugo A; Dobrev, Dobromir; Thomas, Dierk
    Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation
    In: Circulation Jg. 132 (2015) Nr. 2, S. 82 - 92
    ISSN: 0009-7322; 1524-4539
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  • Windecker, Stephan; Cremer, Jochen; Falk, Volkmar; Jüni, Peter; Knuuti, Juhani; Landmesser, Ulf; Neumann, Franz-Josef; Richter, Dimitrios J; Schauerte, Patrick; Taggart, David Paul; Wijns, William; Witkowski, Adam; Achenbach, Stephan; Baumgartner, Helmut; Bueno, Héctor; Deaton, Christi; Ferrari, Roberto; Hasdai, David; Kirchhof, Paulus; Knuuti, Juhani; Lancellotti, Patrizio; Linhart, Ales; Ponikowski, Piotr; Tamargo, Juan Luis; Tendera, Michal; Torbicki, Adam; Windecker, Stephan; Sousa Uva, Miguel; Achenbach, Stephan; Badimon, Lina; Bauersachs, Johann; Baumbach, Andreas; Beygui, Farzin; Bonaros, Nikolaos; Dobrev, Dobromir; Dunning, Joel; Eeckhout, Eric; Gielen, Stephan; Kirchhof, Paulus; Luckraz, Heyman; Mahrholdt, Heiko; Rastan, Ardawan J; Sanmartin, Marcelo; Sergeant, Paul; Silber, Sigmund; Thiele, Holger; van Geuns, Robert-Jan; Wagner, Hans-Otto; Wassmann, Sven; Wendler, Olaf; Zamorano, Jose Luis
    2014 ESC/EACTS Guidelines on myocardial revascularization : the Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Developed with the special contribution
    In: European Journal of Cardio-Thoracic Surgery Jg. 46 (2014) Nr. 4, S. 517 - 592
    ISSN: 1873-734X; 1010-7940; 1567-4258; 1878-3309
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  • Heijman, Jordi; Voigt, Niels; Wehrens, Xander H.T.; Dobrev, Dobromir
    Calcium dysregulation in atrial fibrillation : the role of CaMKII
    In: Frontiers in Pharmacology Jg. 5 (2014) S. 30
    ISSN: 1663-9812
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  • Kreusser, Michael M; Lehmann, Lorenz H; Keranov, Stanislav; Hoting, Marc-Oscar; Oehl, Ulrike; Kohlhaas, Michael; Reil, Jan-Christian; Neumann, Kay; Schneider, Michael D; Hill, Joseph A; Dobrev, Dobromir; Maack, Christoph; Maier, Lars S; Gröne, Hermann-Josef; Katus, Hugo A; Olson, Eric N; Backs, Johannes
    Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy
    In: Circulation Jg. 130 (2014) Nr. 15, S. 1262 - 1273
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  • Heijman, Jordi; Voigt, Niels; Carlsson, Leif G.; Dobrev, Dobromir
    Cardiac safety assays
    In: Current Opinion in Pharmacology Jg. 15 (2014) Nr. 1, S. 16 - 21
    ISSN: 1471-4973
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  • Heijman, Jordi; Voigt, Niels; Nattel, Stanley; Dobrev, Dobromir
    Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
    In: Circulation Research Jg. 114 (2014) Nr. 9, S. 1483 - 1499
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/
  • Voigt, Niels; Heijman, Jordi; Wang, Qiongling; Chiang, David Y.; Li, Na; Karck, Matthias; Wehrens, Xander H.T.; Nattel, Stanley; Dobrev, Dobromir
    Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation
    In: Circulation Jg. 129 (2014) Nr. 2, S. 145 - 156
    ISSN: 1524-4539
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  • Chen, Yu; Wakili, Reza; Xiao, Jiening; Wu, Chia-Tung; Luo, Xiaobing; Clauss, Sebastian; Dawson, Kristin; Qi, Xiaoyan; Naud, Patrice; Shi, Yan-Fen; Tardif, Jean-Claude; Kääb, Stefan; Dobrev, Dobromir; Nattel, Stanley
    Detailed characterization of microRNA changes in a canine heart failure model : Relationship to arrhythmogenic structural remodeling
    In: Journal of Molecular and Cellular Cardiology Jg. 77 (2014) S. 113 - 124
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/
  • Martin, James F.; Dobrev, Dobromir; Wehrens, Xander H.T.; Voigt, Niels; Li, Na; Chiang, David Y.
    GW25-e5168 Impaired Post-Transcriptional Regulation of RyR2 by microRNA-106b-25 Cluster Promotes Atrial Fibrillation
    In: Journal of the American College of Cardiology Jg. 64 (2014) Nr. 16 Suppl., S. C59
    ISSN: 1558-3597
    Online Volltext: dx.doi.org/
  • Chiang, D. Y.; Li, N.; Wang, Q.; Alsina, K. M.; Quick, A. P.; Reynolds, J. O.; Wang, G.; Skapura, D.; Voigt, Niels; Dobrev, Dobromir; Wehrens, Xander H.T.
    Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation
    In: Cardiovascular Research Jg. 103 (2014) Nr. 1, S. 178 - 187
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Voigt, Niels; Heijman, Jordi; Dobrev, Dobromir
    Kardiovaskuläre Pharmakotherapie : Risiken und Nebenwirkungen
    In: Herz Jg. 39 (2014) Nr. 2, S. 227 - 240
    ISSN: 0340-9937
    Online Volltext: dx.doi.org/
  • Chiang, David Y; Kongchan, Natee; Beavers, David L; Alsina, Katherina M; Voigt, Niels; Neilson, Joel R; Jakob, Heinz G.; Martin, James F; Dobrev, Dobromir; Wehrens, Xander H T; Li, Na
    Loss of MicroRNA-106b-25 Cluster Promotes Atrial Fibrillation by Enhancing Ryanodine Receptor Type-2 Expression and Calcium Release
    In: Circulation: Arrhythmia and Electrophysiology Jg. 7 (2014) Nr. 6, S. 1214 - 1222
    ISSN: 1941-3149; 1941-3084
    Online Volltext: dx.doi.org/
  • Harada, Masahide; Luo, Xiaobin; Murohara, Toyoaki; Yang, Baofeng; Dobrev, Dobromir; Nattel, S.
    MicroRNA regulation and cardiac calcium signaling : Role in cardiac disease and therapeutic potential
    In: Circulation Research Jg. 114 (2014) Nr. 4, S. 689 - 705
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir
    Rat engineered heart tissue : a novel tool in the safety pharmacology toolkit?
    In: Basic Research in Cardiology Jg. 109 (2014) Nr. 6, S. 437
    ISSN: 0300-8428
    Online Volltext: dx.doi.org/
  • Dobrev, Dobromir; Wehrens, Xander H. T.
    Role of RyR2 phosphorylation in heart failure and arrhythmias : Controversies around ryanodine receptor phosphorylation in cardiac disease
    In: Circulation Research Jg. 114 (2014) Nr. 8, S. 1311 - 1319
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/
  • Qi, Xiao-Yan; Diness, Jonas G.; Brundel, Bianca J.J.M.; Zhou, Xiao-Bo; Naud, Patrice; Wu, Chia-Tung; Huang, Hai; Harada, Masahide; Aflaki, Mona; Dobrev, Dobromir; Grunnet, Morten; Nattel, Stanley
    Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog
    In: Circulation Jg. 129 (2014) Nr. 4, S. 430 - 440
    ISSN: 1524-4539
    Online Volltext: dx.doi.org/
  • Li, Na; Chiang, David Y.; Wang, Sufen; Wang, Qiongling; Sun, Liang; Voigt, Niels; Respress, Jonathan L.; Ather, Sameer; Skapura, Darlene G.; Jordan, Valerie; Horrigan, Frank T.; Schmitz, Wilhelm; Müller, Frank U.; Valderrabano, Miguel; Nattel, Stanley; Dobrev, Dobromir; Wehrens, Xander H.T.
    Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model
    In: Circulation Jg. 129 (2014) Nr. 12, S. 1276 - 1285
    ISSN: 0009-7322; 0069-4193
    Online Volltext: dx.doi.org/
  • Greiser, Maura; Kerfant, Benoît-Gilles; Williams, George S. B.; Voigt, Niels; Harks, Erik; Dibb, Katharine M.; Giese, Anne; Meszaros, Janos; Verheule, Sander; Ravens, Ursula; Allessie, Maurits A.; Gammie, James S.; Van Der Velden, Jolanda; Lederer, W. Jonathan; Dobrev, Dobromir; Schotten, Ulrich
    Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes
    In: The Journal of Clinical Investigation Jg. 124 (2014) Nr. 11, S. 4759 - 4772
    ISSN: 0021-9738; 1558-8238
    Online Volltext: dx.doi.org/
  • Andrade, J.; Khairy, P.; Dobrev, Dobromir; Nattel, S.
    The clinical profile and pathophysiology of atrial fibrillation : Relationships among clinical features, epidemiology, and mechanisms
    In: Circulation Research Jg. 114 (2014) Nr. 9, S. 1453 - 1468
    ISSN: 1524-4571; 0009-7330
    Online Volltext: dx.doi.org/
  • Guasch, Eduard; Benito, Begoña; Qi, Xiaoyan; Cifelli, Carlo; Naud, Patrice; Shi, Yanfen; Mighiu, Alexandra; Tardif, Jean-Claude; Tadevosyan, Artavazd; Chen, Yu; Gillis, Marc-Antoine; Iwasaki, Yu-Ki; Dobrev, Dobromir; Mont, Lluis; Heximer, Scott; Nattel, Stanley
    Atrial fibrillation promotion by endurance exercise : demonstration and mechanistic exploration in an animal model
    In: Journal of the American College of Cardiology Jg. 62 (2013) Nr. 1, S. 68 - 77
    ISSN: 0735-1097; 1558-3597
    Online Volltext: dx.doi.org/
  • Tsuji, Yukiomi; Heijman, Jordi; Nattel, Stanley; Dobrev, Dobromir
    Electrical storm : recent pathophysiological insights and therapeutic consequences
    In: Basic Research in Cardiology Jg. 108 (2013) Nr. 2, S. 336
    ISSN: 0300-8428; 1435-1803
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dewenter, Matthias; El-Armouche, Ali; Dobrev, Dobromir
    Function and regulation of serine/threonine phosphatases in the healthy and diseased heart
    In: Journal of Molecular and Cellular Cardiology Jg. 64 (2013) S. 90 - 98
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/
  • Voigt, Niels; Heijman, Jordi; Trausch, Anne; Mintert-Jancke, Elisa; Pott, Lutz; Ravens, Ursula; Dobrev, Dobromir
    Impaired Na+-dependent regulation of acetylcholine-activated inward-rectifier K+ current modulates action potential rate dependence in patients with chronic atrial fibrillation
    In: Journal of Molecular and Cellular Cardiology Jg. 61 (2013) S. 142 - 152
    ISSN: 0022-2828; 1095-8584
    Online Volltext: dx.doi.org/
  • Voigt, Niels; Zhou, Xiao-Bo; Dobrev, Dobromir
    Isolation of human atrial myocytes for simultaneous measurements of Ca2+ transients and membrane currents.
    In: Journal of Visualized Experiments (2013) Nr. 77, S. e50235
    ISSN: 1940-087X
    Online Volltext: dx.doi.org/
  • Dawson, Kristin; Wakili, Reza; Ördög, Balázs; Clauss, Sebastian; Chen, Yu; Iwasaki, Yuki; Voigt, Niels; Qi, Xiao Yan; Sinner, Moritz F.; Dobrev, Dobromir; Kääb, Stefan; Nattel, Stanley
    MicroRNA29 : a mechanistic contributor and potential biomarker in atrial fibrillation
    In: Circulation: an official journal of the American Heart Association Jg. 127 (2013) Nr. 14, S. 1466 - 1475
    ISSN: 1524-4539; 0009-7322; 0069-4193; 0065-8499
    Online Volltext: dx.doi.org/
  • Beavers, David L.; Wang, Wei; Ather, Sameer; Voigt, Niels; Garbino, Alejandro; Dixit, Sayali S.; Landstrom, Andrew P.; Li, Na; Wang, Qiongling; Olivotto, Iacopo; Dobrev, Dobromir; Ackerman, Michael J.; Wehrens, Xander H.T.
    Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization
    In: Journal of the American College of Cardiology Jg. 62 (2013) Nr. 21, S. 2010 - 2019
    ISSN: 0735-1097; 1558-3597
    Online Volltext: dx.doi.org/ (Open Access)
  • Levay, Magdolna; Krobert, Kurt Allen; Wittig, Karola; Voigt, Niels; Bermudez, Marcel; Wolber, Gerhard; Dobrev, Dobromir; Levy, Finn Olav; Wieland, Thomas
    NSC23766, a widely used inhibitor of Rac1 activation, additionally Acts as a competitive antagonist at muscarinic acetylcholine receptors
    In: Journal of Pharmacology and Experimental Therapeutics Jg. 347 (2013) Nr. 1, S. 69 - 79
    ISSN: 1521-0103; 0022-3565
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Voigt, Niels; Dobrev, Dobromir
    New directions in antiarrhythmic drug therapy for atrial fibrillation
    In: Future Cardiology Jg. 9 (2013) Nr. 1, S. 71 - 88
    ISSN: 1479-6678; 1744-8298
    Online Volltext: dx.doi.org/
  • Purohit, Anil; Rokita, Adam G.; Guan, Xiaoqun; Chen, Biyi; Koval, Olha M.; Voigt, Niels; Neef, Stefan; Sowa, Thomas; Gao, Zhan; Luczak, Elizabeth D.; Stefansdottir, Hrafnhildur; Behunin, Andrew C.; Li, Na; El-Accaoui, Ramzi N.; Yang, Baoli; Swaminathan, Paari Dominic; Weiss, Robert M.; Wehrens, Xander H.T.; Song, Long-Sheng; Dobrev, Dobromir; Maier, Lars S.; Anderson, Mark E.
    Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation
    In: Circulation Jg. 128 (2013) Nr. 16, S. 1748 - 1757
    ISSN: 1524-4539; 0009-7322; 0065-8499
    Online Volltext: dx.doi.org/
  • Kirchhof, Paulus; Breithardt, Günter; Aliot, Etienne; Al Khatib, Sana; Apostolakis, Stavros; Auricchio, Angelo; Bailleul, Christophe; Bax, Jeroen; Benninger, Gerlinde; Blomstrom-Lundqvist, Carina; Boersma, Lucas; Boriani, Giuseppe; Brandes, Axel; Brown, Helen; Brueckmann, Martina; Calkins, Hugh; Casadei, Barbara; Clemens, Andreas; Crijns, Harry; Derwand, Roland; Dobrev, Dobromir; Ezekowitz, Michael; Fetsch, Thomas; Gerth, Andrea; Gillis, Anne; Gulizia, Michele; Hack, Guido; Haegeli, Laurent; Hatem, Stephane; Georg Häusler, Karl; Heidbüchel, Hein; Hernandez-Brichis, Jessica; Jais, Pierre; Kappenberger, Lukas; Kautzner, Joseph; Kim, Steven; Kuck, Karl-Heinz; Lane, Deirdre; Leute, Angelika; Lewalter, Thorsten; Meyer, Ralf; Mont, Lluis; Moses, Gregory; Mueller, Markus; Münzel, Felix; Näbauer, Michael; Nielsen, Jens Cosedis; Oeff, Michael; Oto, Ali; Pieske, Burkert; Pisters, Ron; Potpara, Tatjana; Rasmussen, Lars; Ravens, Ursula; Reiffel, James; Richard-Lordereau, Isabelle; Schäfer, Herbert; Schotten, Ulrich; Stegink, Wim; Stein, Kenneth; Steinbeck, Gerhard; Szumowski, Lukasz; Tavazzi, Luigi; Themistoclakis, Sakis; Thomitzek, Karen; Van Gelder, Isabelle C; von Stritzky, Berndt; Vincent, Alphons; Werring, David; Willems, Stephan; Lip, Gregory Y H; Camm, A John
    Personalized management of atrial fibrillation : Proceedings from the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association consensus conference
    In: EP Europace Jg. 15 (2013) Nr. 11, S. 1540 - 1556
    ISSN: 1532-2092; 1099-5129
    Online Volltext: dx.doi.org/
  • Mehel, Hind; Emons, Julius; Vettel, Christiane; Wittköpper, Katrin; Seppelt, Danilo; Dewenter, Matthias; Lutz, Susanne; Sossalla, Samuel; Maier, Lars S.; Lechêne, Patrick; Leroy, Jérôme; Lefebvre, Florence; Varin, Audrey; Eschenhagen, Thomas; Nattel, Stanley; Dobrev, Dobromir; Zimmermann, Wolfram-Hubertus; Nikolaev, Viacheslav O.; Vandecasteele, Grégoire; Fischmeister, Rodolphe; El-Armouche, Ali
    Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes
    In: Journal of the American College of Cardiology Jg. 62 (2013) Nr. 17, S. 1596 - 1606
    ISSN: 0735-1097; 1558-3597
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir
    Pleiotropic actions of amiodarone : still puzzling after half a century
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 386 (2013) Nr. 7, S. 571 - 574
    ISSN: 0028-1298; 1432-1912
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Heusch, Gerd; Dobrev, Dobromir
    Pleiotropic effects of antiarrhythmic agents : dronedarone in the treatment of atrial fibrillation
    In: Clinical Medicine Insights: Cardiology Jg. 7 (2013) S. 127 - 140
    ISSN: 1179-5468; 1178-1165
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Voigt, Niels; Abu-Taha, Issam H; Dobrev, Dobromir
    Rhythm control of atrial fibrillation in heart failure
    In: Heart Failure Clinics Jg. 9 (2013) Nr. 4, S. 407 - 415
    ISSN: 1551-7136
    Online Volltext: dx.doi.org/
  • Tsuji, Yukiomi; Dobrev, Dobromir
    Safety and efficacy of vernakalant for acute cardioversion of atrial fibrillation : an update
    In: Vascular Health and Risk Management Jg. 9 (2013) S. 165 - 175
    ISSN: 1176-6344; 1178-2048
    Online Volltext: dx.doi.org/
  • Le Quang, Khai; Benito, Begoña; Naud, Patrice; Qi, Xiao Yan; Shi, Yan Fen; Tardif, Jean-Claude; Gillis, Marc-Antoine; Dobrev, Dobromir; Charpentier, Flavien; Nattel, Stanley
    T-type calcium current contributes to escape automaticity and governs the occurrence of lethal arrhythmias after atrioventricular block in mice
    In: Circulation: Arrhythmia and Electrophysiology Jg. 6 (2013) Nr. 4, S. 799 - 808
    ISSN: 1941-3149; 1941-3084
    Online Volltext: dx.doi.org/
  • Voigt, Niels; Dobrev, Dobromir
    The biology of human pulmonary veins : does it help us to better understand AF pathophysiology in patients?
    In: Heart Rhythm Jg. 10 (2013) Nr. 3, S. 392 - 393
    ISSN: 1547-5271; 1556-3871
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Nückel, Holger; Dobrev, Dobromir; Manthey, Iris; Sandalcioglu, Erol; Eisenhardt, Andreas; Worm, Karl; Hauner, Hans; Siffert, Winfried
    Quantification of G protein Gαs subunit splice variants in different human tissues and cells using pyrosequencing
    In: Gene Expression Jg. 12 (2004) Nr. 2, S. 69 - 81
    ISSN: 1052-2166
    Online Volltext: dx.doi.org/ (Open Access)

    • Vorworte / Nachworte

  • Bruns, Florian; Dobrev, Dobromir
    Assessment of atrial function by echocardiography : Can this be used to assess the arrhythmogenic atrial substrate?
    In: International Journal of Cardiology (2022) in press
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Tsuji, Yukiomi; Dobrev, Dobromir
    Chronic total occlusion of infarct-related artery : A bystander or a risk factor of electrical storm?
    In: International Journal of Cardiology (2022)
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Gawałko, Monika; Dobrev, Dobromir
    Fat chance for POAF? : Pericardial adipose tissue and the arrhythmogenic substrate for postoperative atrial fibrillation
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 39 (2022)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Bruns, Florian; Dobrev, Dobromir
    Minding the gap – Heterogeneity of antithrombotic treatment preferences in complex scenarios in absence of evidence-based guidelines
    In: International Journal of Cardiology Jg. 348 (2022) S. 83 - 84
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    The temporal context of oral anticoagulation outcome in atrial fibrillation
    In: International Journal of Cardiology (IJC) Heart & Vasculature (2022)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Dobrev, Dobromir
    A disproportional rise in the growing submission rate to International Journal of Cardiology Heart & Vasculature during the COVID‑19 pandemic
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 33 (2021) S. 100749
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Childhood infection and modern malnutrition : Do childhood infections create an inflammatory foundation for atherosclerosis in adult life?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 35 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Gawałko, Monika; Linz, Dominik; Dobrev, Dobromir
    Gut-microbiota derived TMAO : A risk factor, a mediator or a bystander in the pathogenesis of atrial fibrillation?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 34 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Tsuji, Yukiomi; Dobrev, Dobromir
    Implantable cardioverter-defibrillator therapy in primary versus secondary prevention : Reliable prediction of appropriate therapies and mortality is still an unmet need
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 32 (2021) S. 100740
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Nitric oxide as a fragile switch between cardioprotection and cardiac injury
    In: International Journal of Cardiology Jg. 343 (2021) S. 102 - 103
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Linz, Dominik; Linz, Benedikt; Homberg, Marloes; Bouman, Esther; Dobrev, Dobromir; Hendriks, Jeroen M.; Simons, Sami O.
    Obstructive respiratory events during procedural sedation and analgesia : Another WHY to routinely screen for sleep apnea before catheter ablation of atrial fibrillation
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 33 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Aguilar, Martin; Heijman, Jordi; Dobrev, Dobromir; Nattel, Stanley
    One Ring to Rule Them All : Continuous Monitoring of Patients With Secondary Atrial Fibrillation Points to a Unifying Underlying Mechanism
    In: Canadian Journal of Cardiology (CJC) Jg. 37 (2021) Nr. 5, S. 686 - 689
    ISSN: 0828-282X; 1916-7075
    Online Volltext: dx.doi.org/
  • Gawałko, Monika; Dobrev, Dobromir
    Oral anticoagulation and therapy of atrial flutter : Discontinuation of anticoagulation revisited
    In: International Journal of Cardiology Jg. 333 (2021) S. 117 - 118
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Dobrev, Dobromir; Dudley, Samuel C
    Oxidative stress: a baystander or a causal contributor to atrial remodelling and fibrillation?
    In: Cardiovascular Research Jg. 117 (2021) Nr. 11, S. 2291 - 2293
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Linz, Benedikt; Dobrev, Dobromir; Baumert, Mathias; Hendriks, Jeroen M.; Pepin, Jean-Louis; Jespersen, Thomas
    Personalized management of sleep apnea in patients with atrial fibrillation : An interdisciplinary and translational challenge
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 35 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Potential antiarrhythmic actions of anticoagulants : Do they exist and can they be clinically unmasked?
    In: International Journal of Cardiology Jg. 331 (2021) S. 73 - 74
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Song, Jia; Dobrev, Dobromir; Li, Na
    Proteomics : A promising approach to discover new biomarkers for atrial fibrillation
    In: International Journal of Cardiology Jg. 345 (2021) S. 125 - 126
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Soluble fibrin monomer complex as a candidate sentinel for adverse events in patients with heart failure
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 32 (2021) S. 100712
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Heijman, Jordi; Rahm, Ann-Kathrin; Dobrev, Dobromir
    Stretching the limits of antiarrhythmic drug therapy : The promise of small-conductance calcium-activated potassium channel blockers
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 37 (2021)
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Riesinger, Lisa M.; Wakili, Reza; Dobrev, Dobromir
    Stroke prevention of atrial fibrillation : Improving geographic under-use of contemporary antithrombotic approaches remains a challenge
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 34 (2021) S. 100785
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    The anticoagulation dilemma and future treatment avenues in patients with breast cancer and atrial fibrillation
    In: International Journal of Cardiology Jg. 323 (2021) S. 194 - 196
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Ehrlich, Joachim R.; Dobrev, Dobromir
    Therapy-refractory AF : A clear unmet need for the development of novel antiarrhythmic drugs
    In: International Journal of Cardiology Jg. 331 (2021) S. 114 - 115
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Contemporary plaque imaging for risk stratification of coronary artery disease : Are we getting there?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 31 (2020) S. 100678
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Coronary clot composition after myocardial infarction : Thrombus age matters
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 26 (2020) S. 100450
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Nedios, Sotirios; Dobrev, Dobromir
    Electrocardiographic sex-related differences in patients with atrial fibrillation : Do they allow a better risk stratification?
    In: International Journal of Cardiology Jg. 307 (2020) S. 73 - 74
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Heart failure with preserved ejection fraction meets atrial fibrillation : Is enhanced inflammasome signaling a major common mechanism leading to these two frequent diseases?
    In: Heart Rhythm Jg. 17 (2020) Nr. 6, S. 1034 - 1035
    ISSN: 1556-3871; 1547-5271
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    One for all and all for one? : The dilemma of optimal management of atrial fibrillation with cardiac co-morbidities
    In: International Journal of Cardiology Jg. 299 (2020) S. 175 - 176
    ISSN: 1874-1754; 0167-5273
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Pleiotropic actions of ticagrelor versus clopidogrel – Do molecular differences translate into superior clinical efficacy after myocardial infarction?
    In: International Journal of Cardiology (IJC) Heart & Vasculature (2020) Article-No: 100508
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Dan, Gheorghe-Andrei; Dobrev, Dobromir
    Polypill revisited – Unity in diversity
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 29 (2020) S. 100607
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Barrios Espinosa, Cristian; Hemels, Martin E.W.; Dobrev, Dobromir; Heijman, Jordi
    Recurrence of atrial fibrillation following non-cardiac surgery or acute illness : A common but rarely detected complication
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 29 (2020) S. 100609
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Gawałko, Monika; Jespersen, Thomas; Dobrev, Dobromir; Linz, Dominik
    The gut microbial-derived metabolite trimethylamine N-oxide : A missing link between lifestyle-components and atrial fibrillation?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 29 (2020) S. 100581
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Anticoagulation in difficult settings RELOADed : Evidence for applicability of direct oral anticoagulants in patients with atrial fibrillation, renal impairment and cancer
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 23 (2019) S. 100374
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir
    Atrial Ca²⁺/calmodulin-dependent protein kinase II : A druggable master switch of atrial fibrillation-associated atrial remodeling?
    In: Heart Rhythm Jg. 16 (2019) Nr. 7, S. 1089 - 1090
    ISSN: 1556-3871; 1547-5271
    Online Volltext: dx.doi.org/
  • Linz, Dominik; Sanders, Prashanthan; Pitman, Bradley; Dobrev, Dobromir; Lau, Dennis H.
    Atrial fibrillation in sub-Saharan Africa : The knowns and unknowns?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 22 (2019) S. 212 - 213
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Fender, Anke C.; Dobrev, Dobromir
    Bound to bleed: How altered albumin binding may dictate warfarin treatment outcome
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 22 (2019) S. 214 - 215
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Sutanto, H.; Dobrev, Dobromir; Heijman, Jordi
    Genome-wide association studies of atrial fibrillation : Finding meaning in the life of risk loci
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 24 (2019) S. 100397
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Ammirati, Enrico; Dan, Gheorghe-Andrei; Heijman, Jordi; Dobrev, Dobromir
    Highlights from the II International Journal of Cardiology Heart & Vasculature : Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 25 (2019) S. 100443
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Linz, Dominik; Dobrev, Dobromir
    Outcome of atrial fibrillation ablation in pulmonary hypertension : Is pulmonary hypertension a modifiable risk factor?
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 23 (2019) S. 100360
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Ciuculete, Denisa Corina; Dobrev, Dobromir; Dan, G.-Andrei
    Prognostic value of biomarkers of impaired metabolism in heart failure patients with reduced ejection fraction
    In: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 25 (2019) S. 100441
    ISSN: 2352-9067
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir; Fender, Anke C.; Wehrens, Xander H.T.
    Pro-arrhythmic RyR2 channels in heart failure : Do their localisation and mechanism of activation really matter?
    In: Cardiovascular Research Jg. 114 (2018) Nr. 11, S. 1428 - 1429
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/
  • Tsuji, Yukiomi; Dobrev, Dobromir
    Prognostic impact of electrical storm in patients with implantable cardioverter defibrillators : mechanistic and therapeutic considerations to reduce the risk of death
    In: International Journal of Cardiology Jg. 255 (2018) S. 101 - 102
    ISSN: 0167-5273; 0167-5273
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Na; Dobrev, Dobromir
    Targeting atrial fibrillation promoting atrial structural remodeling : is this a viable strategy in patients with heart failure?
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 391 (2018) Nr. 3, S. 231 - 233
    ISSN: 1432-1912; 0028-1298
    Online Volltext: dx.doi.org/
  • Fender, Anke C.; Dobrev, Dobromir
    Dynamic balance of platelet reactivity in atrial fibrillation PARtially unravelled
    In: International Journal of Cardiology Jg. 243 (2017) S. 272 - 273
    ISSN: 0167-5273; 1874-1754
    Online Volltext: dx.doi.org/
  • Li, Na; Dobrev, Dobromir
    Hyperuricemia : a causal player or a bystander linking inflammatory signaling and atrial fibrillation?
    In: International Journal of Cardiology Jg. 231 (2017) S. 177 - 178
    ISSN: 0167-5273; 1874-1754
    Online Volltext: dx.doi.org/
  • Wakili, Reza; Dobrev, Dobromir
    Role of triggers and substrate in heart failure based atrial fibrillation : is pulmonary vein isolation still the cornerstone of atrial fibrillation therapy?
    In: International Journal of Cardiology Jg. 243 (2017) S. 276 - 278
    ISSN: 0167-5273; 1874-1754
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir; Crijns, Harry J.G.M.
    Targeting supraventricular ectopic complexes : which approach should be used and how does it affect atrial fibrillation?
    In: International Journal of Cardiology Jg. 244 (2017) S. 202 - 203
    ISSN: 0167-5273; 1874-1754
    Online Volltext: dx.doi.org/ (Open Access)
  • Dobrev, Dobromir
    Unique cardiomyocyte ultrastructure in atria : role of T tubules in subcellular Ca²⁺ signaling and atrial arrhythmogenesis
    In: Heart Rhythm Jg. 14 (2017) Nr. 2, S. 282 - 283
    ISSN: 1547-5271; 1556-3871
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Wehrens, X H T; Dobrev, Dobromir
    Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia – is there a mechanistic link between sarcoplasmic reticulum Ca2+ leak and re‐entry?
    In: Acta Physiologica Jg. 207 (2013) Nr. 2, S. 208 - 211
    ISSN: 1748-1708; 1748-1716
    Online Volltext: dx.doi.org/
  • Heijman, Jordi; Dobrev, Dobromir
    KCNQ1 autoantibodies : another way to regulate IKs
    In: Cardiovascular Research Jg. 98 (2013) Nr. 3, S. 329 - 331
    ISSN: 0008-6363; 1755-3245
    Online Volltext: dx.doi.org/

    • Abstracts

  • Fogli Iseppe, Alex; Morotti, Stefano; Tekook, Marcel; Hoffmann, Dennis; Edwards, Andrew G.; Dobrev, Dobromir; Grandi, Eleonora
    A Modeling Framework for Investigating the Role of Human Atrial Fibroblast Calcium Signaling in Fibrogenesis
    In: Biophysical Journal: BJ Jg. 120 (2021) Nr. 3, Supplement 1, S. 53a - 54a
    ISSN: 1542-0086; 0006-3495
    Online Volltext: dx.doi.org/
  • Kupusovic, J.; Weber, Manuel; Kessler, Lukas; Pesch, E.; Riesinger, L.; Wakili, Reza; Dobrev, Dobromir; Rischpler, Christoph; Rassaf, Tienush; Siebermair, Johannes
    Increased FDG uptake in AF individuals suggesting atrial inflammation visualized by FDG PET/CT with glucose uptake suppression protocols
    In: European Heart Journal Jg. 42 (2021) Nr. Supplement_1,
    ISSN: 0195-668X; 1522-9645
    Online Volltext: dx.doi.org/ (Open Access)
  • Mittendorf, C.; Poertner, J.; Kassler, L.; Puzicha, T.; Kamler, Markus; Dobrev, Dobromir; Fender, A.;
    Thrombin receptor PAR4 coordinates inflammatory stress platforms in diabetic atria
    87th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) ; 1 March – 3 March 2021, Digital,
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 394 (2021) Nr. Suppl. 1, S. S6
    ISSN: 1432-1912; 0028-1298
    Online Volltext: dx.doi.org/
  • Dülk, R.; Mason, F. E.; Schönhals, S.; Dobrev, Dobromir; Zimmermann, W. H.; Rickert-Sperling, S.; Voigt, Niels;
    Abnormal cellular electrophysiology and calcium handling in iPSC-CMs from a patient with tetralogy of Fallot
    84th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 20th Annual Meeting of the Association of the Clinical Pharmacology Germany (VKliPha) ; 26 February – 1 March 2018. Göttingen,
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 391 (2018) Nr. 1, Supplement, S. S18
    ISSN: 0028-1298; 1432-1912
    Online Volltext: dx.doi.org/
  • Moretti, Stefano; Ellinwood, Nicholas; Ni, Haibo; Koivumäki, Jussi T.; Maleckar, Mary M.; Heijman, Jordi; Dobrev, Dobromir; Grandi, Eleonora;
    Effects of Modulation of Small-Conductance Calcium-Activated Potassium Current on Atrial Electrophysiology and Arrhythmogenesis : A Population-Based Computational Study
    62nd Annual Meeting of the Biophysical Society ; February 17-21, 2018, San Francisco,
    In: Biophysical Journal Jg. 114 (2018) Nr. 3, Suppl. 1, S. 473a
    ISSN: 0006-3495; 1542-0086
    Online Volltext: dx.doi.org/
  • Dobrev, Dobromir
    Proarrhythmic Subcellular Signaling in Atrial Fibrillation : Role of Calcium Dependent Potassium Channels
    In: Cardiology / 23rd World Congress on Heart Disease ; July 27–29, 2018, Boston Jg. 140 (2018) Nr. Suppl. 1, S. 79
    ISSN: 0008-6312; 1421-9751
    Online Volltext: dx.doi.org/
  • Eschenhagen, T; Carrier, L; Cuello, F; Boontje, N; Stathopoulou, K; Voigt, Niels; Buck, F; Schröder, Elisabeth; Dobrev, Dobromir; Van Der Velden, J
    P678: S-glutathiolation of cMyBP-C reduces its phosphorylation and contributes to impairment of cardiac myocyte contractile function
    In: Cardiovascular Research Jg. 103 (2014) S. S123 - S124
    ISSN: 1755-3245; 0008-6363
    Online Volltext: dx.doi.org/ (Open Access)

    • Beiträge in Sammelwerken und Tagungsbänden

  • Nattel, Stanley; Heijman, Jordi; Voigt, Niels; Wehrens, Xander H.T.; Dobrev, Dobromir
    The Molecular Pathophysiology of Atrial Fibrillation
    In: Cardiac Electrophysiology: From Cell to Bedside / Zipes, Douglas P.; Jalife, José; Stevenson, William G. (Hrsg.) 2018, S. 396 - 408
    ISBN: 9780323447331
    Online Volltext: dx.doi.org/
  • Dobrev, Dobromir; Voigt, Niels; Nattel, Stanley
    Cholinergic and Constitutive Regulation of Atrial Potassium Channel
    In: Cardiac Electrophysiology: From Cell to Bedside / Zipes, Douglas P.; Jalife, José 2014, S. 383 - 391
    ISBN: 978-1-4557-7010-6; 978-1-4557-2856-5
    Online Volltext: dx.doi.org/
  • Voigt, Niels; Abu-Taha, Issam; Hejman, Jordi; Dobrev, Dobromir
    Constitutive Activity of the Acetylcholine-Activated Potassium Current IK,ACh in Cardiomyocytes
    In: Pharmacology & Therapeutics of Constitutively Active Receptors / Tao, Ya-Xiong (Hrsg.) 2014, S. 393 - 409
    ISBN: 978-0-12-417197-8; 978-0-12-417206-7
    Online Volltext: dx.doi.org/
  • Nattel, Stanley; Voigt, Niels; Dobrev, Dobromir
    The Molecular Pathophysiology of Atrial Fibrillation
    In: Cardiac Electrophysiology: From Cell to Bedside / Zipes, Douglas P.; Jalife, José (Hrsg.) 2013, S. 449 - 458
    ISBN: 978-1-4557-7010-6; 978-1-4557-2856-5
    Online Volltext: dx.doi.org/