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Dr. rer. nat. Vu Thuy Khanh Le-Trilling

Funktionen

  • Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Virologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Tang, Haihuan; Hu, Jie; Schmitz, Mona S.; Barbet, Kimberly; Xu, Dan; Wei, Zhen; Guo, Beinu; Mennerich, Denise; Yao, Chun; Liu, Jinxin; Li, Zhenghan; Wan, Yushun; Zhang, Xiaoyong; Wang, Kai; Tang, Ni; Yu, Zebo; Trilling, Mirko; Lin, Yong
    Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin
    In: Virus Research , Jg. 350 2024 , 199485
    DOI (Open Access)
  • Gerke, Carolin; Bauersfeld, Liane; Schirmeister, Ivo; Mireisz, Chiara Noemi-Marie; Oberhardt, Valerie; Mery, Lea; Wu, Di; Jürges, Christopher Sebastian; Spaapen, Robbert M.; Mussolino, Claudio; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Dölken, Lars; Paster, Wolfgang; Erhard, Florian; Hofmann, Maike; Schlosser, Andreas; Hengel, Hartmut; Momburg, Frank; Halenius, Anne
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
    In: eLife , Jg. 13 2024 , e85560
    DOI (Open Access)
  • Thomas, Alexander; Battenfeld, Thomas; Kraiselburd, Ivana; Anastasiou, Olympia; Dittmer, Ulf; Dörr, Ann-Kathrin; Dörr, Adrian; Elsner, Carina; Gosch, Jule; Le-Trilling, Vu Thuy Khanh; Magin, Simon; Scholtysik, René; Yilmaz, Pelin; Trilling, Mirko; Schöler, Lara; Köster, Johannes; Meyer, Folker
    UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an example
    In: BMC Genomics , Jg. 25 2024 , Nr. 1 , 647
    DOI, Online Volltext (Open Access)
  • Anastasiou, Olympia E.; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    A simple algorithm based on initial Ct values predicts the duration to SARS-CoV-2 negativity and allows more efficient test-to-release and return-to-work schedules
    In: Diagnostic Microbiology and Infectious Disease , Jg. 106 2023 , Nr. 3 , 115949
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Ebel, Jana‐Fabienne; Baier, Franziska; Wohlgemuth, Kerstin; Pfeifer, Kai Robin; Mookhoek, Aart; Krebs, Philippe; Determann, Madita; Katschinski, Benjamin; Adamczyk, Alexandra; Lange, Erik; Klopfleisch, Robert; Lange, Christian; Sokolova, Viktoriya; Trilling, Mirko; Westendorf, Astrid
    Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cells
    In: European Journal of Immunology , Jg. 53 2023 , Nr. 2 , 2249940
    DOI (Open Access)
  • Holtkamp, Caroline; Schöler, Lara; Anastasiou, Olympia E.; Brune, Bastian; Fessmann, Kai; Elsner, Carina; Möhlendick, Birte; Ciuciulkaite, Ieva; Dudda, Marcel; Trilling, Mirko; Dittmer, Ulf; Spors, Jörg; Le-Trilling, Vu Thuy Khanh
    Antibody responses elicited by mRNA vaccination in firefighters persist six months and correlate inversely with age and directly with BMI
    In: Heliyon , Jg. 9 2023 , Nr. 1 , e12746
    DOI, Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Maaßen, Fabienne; Katschinski, Benjamin; Hengel, Hartmut; Trilling, Mirko
    Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation
    In: Frontiers in Immunology , Jg. 14 2023 , 1170300
    DOI, Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Jagnjić, Andreja; Brizić, Ilija; Eilbrecht, Mareike; Wohlgemuth, Kerstin; Rožmanić, Carmen; Herdman, Alan; Hoffmann, Katja; Westendorf, Astrid M.; Hengel, Hartmut; Jonjić, Stipan; Trilling, Mirko
    Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus
    In: npj Vaccines , Jg. 8 2023 , Nr. 1 , 8
    DOI, Online Volltext (Open Access)
  • Di Vito, Clara; Coianiz, Nicolò; Calvi, Michela; Terzoli, Sara; Zaghi, Elisa; Puccio, Simone; Frigo, Alessandro; Mariotti, Jacopo; De Philippis, Chiara; Mannina, Daniele; Sarina, Barbara; Mineri, Rossana; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Castagna, Luca; Bramanti, Stefania; Santoro, Armando; Mavilio, Domenico
    Persistence of KIRⁿeg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivation
    In: Frontiers in Immunology , Jg. 14 2023 , 1266051
    DOI (Open Access)
  • Gonzalez-Rubio, Julian; Le-Trilling, Vu Thuy Khanh; Baumann, Lea; Cheremkhina, Maria; Kubiza, Hannah; Luengen, Anja E.; Reuter, Sebastian; Taube, Christian; Ruetten, Stephan; Duarte Campos, Daniela; Cornelissen, Christian G.; Trilling, Mirko; Thiebes, Anja Lena
    SARS-CoV-2 particles promote airway epithelial differentiation and ciliation
    In: Frontiers in Bioengineering and Biotechnology , Jg. 11 2023 , 1268782
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Banchenko, Sofia; Paydar, Darius; Leipe, Pia Madeleine; Binting, Lukas; Lauer, Simon; Graziadei, Andrea; Klingen, Robin; Gotthold, Christine; Bürger, Jörg; Bracht, Thilo; Sitek, Barbara; Lebbink, Robert Jan; Malyshkina, Anna; Mielke, Thorsten; Rappsilber, Juri; Spahn, Christian; Voigt, Sebastian; Trilling, Mirko; Schwefel, David
    Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
    In: The EMBO Journal , Jg. 42 2023 , Nr. 5 , e112351
    DOI (Open Access)
  • Karakoese, Zehra; Le-Trilling, Vu Thuy Khanh; Schuhenn, Jonas; Francois, Sandra; Lu, Mengji; Liu, Jia; Trilling, Mirko; Hoffmann, Daniel; Dittmer, Ulf; Sutter, Kathrin
    Targeted mutations in IFNα2 improve its antiviral activity against various viruses
    In: mBio , Jg. 14 2023 , Nr. 6 , e02357-23
    DOI, Online Volltext (Open Access)
  • Schuhenn, Jonas; Meister, Toni Luise; Todt, Daniel; Bracht, Thilo; Schork, Karin; Billaud, Jean-Noel; Elsner, Carina; Heinen, Natalie; Karakoese, Zehra; Haid, Sibylle; Kumar, Sriram; Brunotte, Linda; Eisenacher, Martin; Di, Yunyun; Lew, Jocelyne; Falzarano, Darryl; Chen, Jieliang; Yuan, Zhenghong; Pietschmann, Thomas; Wiegmann, Bettina; Uebner, Hendrik; Taube, Christian; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Krawczyk, Adalbert; Ludwig, Stephan; Sitek, Barbara; Steinmann, Eike; Dittmer, Ulf; Lavender, Kerry J.; Sutter, Kathrin; Pfaender, Stephanie
    Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 119 2022 , Nr. 8 , e2111600119
    DOI (Open Access)
  • Dehnen, Dorothea; Dehnen, Katja; Trilling, Mirko; Fiedler, Melanie; Drexler, Julia; Goralski, Marcel; Le-Trilling, Vu Thuy Khanh; Schöler, Lara; Jöckel, Karl-Heinz; Heßbrügge, Martina
    Discrepancy between frequent occurrence of COVID-19-like symptoms and low seroconversion rates among healthcare workers
    In: Journal of Medical Virology , Jg. 94 2022 , Nr. 3: Special Issue on New coronavirus (2019‐nCoV or SARS‐CoV‐2) and the outbreak of the respiratory illness (COVID‐19): Part‐XVIII , S. 951 - 957
    DOI (Open Access)
  • Schöler, Lara; Le-Trilling, Vu Thuy Khanh; Dittmer, Ulf; Fiedler, Melanie; Trilling, Mirko
    Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies virus neutralizing antibodies
    In: PLoS Neglected Tropical Diseases , Jg. 16 2022 , Nr. 5 , e0010425
    DOI, Online Volltext (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Mennerich, Denise; Schuler, Corinna; Sakson, Roman; Lill, Julia K.; Kasarla, Siva Swapna; Kopczynski, Dominik; Loroch, Stefan; Flores-Martinez, Yulia; Katschinski, Benjamin; Wohlgemuth, Kerstin; Gunzer, Matthias; Meyer, Folker; Phapale, Prasad; Dittmer, Ulf; Sickmann, Albert; Trilling, Mirko
    Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro
    In: BMC Biology (incorporating Journal of Biology) , Jg. 20 2022 , Nr. 1 , 264
    DOI, Online Volltext (Open Access)
  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Wang, Kai; Mennerich, Denise; Hu, Jie; Zhao, Zhenyu; Zheng, Jiaxin; Deng, Yingying; Katschinski, Benjamin; Xu, Shilei; Zhang, Guiji; Cai, Xuefei; Hu, Yuan; Wang, Jianwei; Lu, Mengji; Huang, Ailong; Tang, Ni; Trilling, Mirko; Lin, Yong
    Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
    In: Emerging Microbes & Infections , Jg. 11 2022 , Nr. 1 , S. 483 - 497
    DOI (Open Access)
  • Krempe, Friederike; Schöler, Lara; Katschinski, Benjamin; Herrmann, Anke; Anastasiou, Olympia E.; Elsner, Carina; Roß, R. Stefan; Scholz, Friedrich; Dittmer, Ulf; Miethe, Peter; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    A rapid test recognizing mucosal SARS-CoV-2-specific antibodies distinguishes prodromal from convalescent COVID-19
    In: iScience , Jg. 24 2021 , Nr. 10 , 103194
    DOI (Open Access)
  • Kolb, Philipp; Hoffmann, Katja; Sievert, Annika; Reinhard, Henrike; Mercé-Maldonado, Eva; Le-Trilling, Vu Thuy Khanh; Halenius, Anne; Gütle, Dominique; Hengel, Hartmut
    Human cytomegalovirus antagonizes activation of fcγ receptors by distinct and synergizing modes of igg manipulation
    In: eLife , Jg. 10 2021 , S. e63877
    DOI (Open Access)
  • Flores-Martínez, Yulia Alejandra; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Nedd8-activating enzyme is a druggable host dependency factor of human and mouse cytomegalovirus
    In: Viruses , Jg. 13 2021 , Nr. 8 , 1610
    DOI, Online Volltext (Open Access)
  • Wu, Jun; Liang, Bo-Yun; Fang, Yao-Hui; Wang, Hua; Yang, Xiao-Li; Shen, Shu; Chen, Liang-Kai; Li, Su-Meng; Lu, Si-Hong; Xiang, Tian-Dan; Liu, Jia; Le-Trilling, Vu Thuy Khanh; Lu, Mengji; Yang, Dong-Liang; Deng, Fei; Dittmer, Ulf; Trilling, Mirko; Zheng, Xin
    Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral Immunity
    In: Frontiers in Immunology , Jg. 12 2021 , 722027
    DOI, Online Volltext (Open Access)
  • Klingen, Robin L.; Katschinski, Benjamin; Anastasiou, Olympia E.; Roß, Rudolf Stefan; Dittmer, Ulf; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Over 90% of clinical swabs used for SARS-CoV-2 diagnostics contain sufficient nucleic acid concentrations
    In: Journal of Medical Virology , Jg. 93 2021 , Nr. 5 , S. 2848 - 2856
    DOI (Open Access)
  • Huang, Hongming; Rückborn, Meike; Le-Trilling, Vu Thuy Khanh; Zhu, Dan; Yang, Shangqing; Zhou, Wenqing; Yang, Xuecheng; Feng, Xuemei; Lu, Yinping; Lu, Mengji; Dittmer, Ulf; Yang, Dongliang; Trilling, Mirko; Liu, Jia
    Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in mice
    In: European Journal of Immunology , Jg. 51 2021 , Nr. 2 , S. 393 - 407
    DOI (Open Access)
  • Zaghi, Elisa; Calvi, Michela; Puccio, Simone; Spata, Gianmarco; Terzoli, Sara; Peano, Clelia; Roberto, Alessandra; De Paoli, Federica; van Beek, Jasper J.P.; Mariotti, Jacopo; De Philippis, Chiara; Sarina, Barbara; Mineri, Rossana; Bramanti, Stefania; Santoro, Armando; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Marcenaro, Emanuela; Castagna, Luca; Di Vito, Clara; Lugli, Enrico; Mavilio, Domenico
    Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT
    In: JCI Insight , Jg. 6 2021 , Nr. 12 , e146973
    DOI (Open Access)
  • Seidel, Einat; Dassa, Liat; Schuler, Corinna; Oiknine-Djian, Esther; Wolf, Dana G.; Le-Trilling, Vu Thuy Khanh; Mandelboim, Ofer; Stanton, Richard James
    The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele : MICA*008, to evade NK cell-mediated killing
    In: PLoS Pathogens , Jg. 17 2021 , Nr. 5 , S. e1008807
    DOI (Open Access)
  • Bormann, Maren; Alt, Mira; Schipper, Leonie; van de Sand, Lukas; Le-Trilling, Vu Thuy Khanh; Rink, Lydia; Heinen, Natalie; Madel, Rabea Julia; Otte, Mona; Wuensch, Korbinian; Heilingloh, Christiane Silke; Mueller, Thorsten; Dittmer, Ulf; Elsner, Carina; Pfaender, Stephanie; Trilling, Mirko; Witzke, Oliver; Krawczyk, Adalbert
    Turmeric root and its bioactive ingredient curcumin effectively neutralize sars-cov-2 in vitro
    In: Viruses , Jg. 13 2021 , Nr. 10 , 1914
    DOI, Online Volltext (Open Access)
  • Schöler, Lara; Le-Trilling, Vu Thuy Khanh; Eilbrecht, Mareike; Mennerich, Denise; Anastasiou, Olympia E.; Krawczyk, Adalbert; Herrmann, Anke; Dittmer, Ulf; Trilling, Mirko
    A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds
    In: Frontiers in Immunology , Jg. 11 2020 , S. 573526
    DOI, Online Volltext (Open Access)
  • Lübke, Maren; Spalt, Stefanie; Kowalewski, Daniel J.; Zimmermann, Cosima; Bauersfeld, Liane; Nelde, Annika; Bichmann, Leon; Marcu, Ana; Peper, Janet Kerstin; Kohlbacher, Oliver; Walz, Juliane S.; Le-Trilling, Vu Thuy Khanh; Hengel, Hartmut; Rammensee, Hans-Georg; Stevanović, Stefan; Halenius, Anne
    Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models
    In: Journal of Experimental Medicine (JEM) , Jg. 217 2020 , Nr. 3 , S. e20191164
    DOI (Open Access)
  • Eilbrecht, Mareike; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication
    In: Frontiers in Cellular and Infection Microbiology , Jg. 10 2020 , 171
    DOI, Online Volltext (Open Access)
  • Such, Lina; Zhao, Fang; Liu, Derek; Thier, Beatrice; Le-Trilling, Vu Thuy Khanh; Sucker, Antje; Coch, Christoph; Pieper, Natalia; Howe, Sebastian; Bhat, Hilal; Kalkavan, Halime; Ritter, Cathrin; Brinkhaus, Robin; Ugurel, Selma; Köster, Johannes; Seifert, Ulrike; Dittmer, Ulf; Schuler, Martin; Lang, Karl S.; Kufer, Thomas A.; Hartmann, Gunther; Becker, Jürgen; Horn, Susanne; Ferrone, Soldano; Liu, David; Van Allen, Eliezer M.; Schadendorf, Dirk; Griewank, Klaus; Trilling, Mirko; Paschen, Annette
    Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy
    In: The Journal of Clinical Investigation (JCI) , Jg. 130 2020 , Nr. 8 , S. 4266 - 4281
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Becker, Tanja; Nachshon, Aharon; Stern-Ginossar, Noam; Schöler, Lara; Voigt, Sebastian; Hengel, Hartmut; Trilling, Mirko
    The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity
    In: Cell Reports , Jg. 30 2020 , Nr. 7 , S. 2248 - 2260.e5
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Ub to no good : How cytomegaloviruses exploit the ubiquitin proteasome system
    In: Virus Research , Jg. 281 2020 , S. 197938
    DOI
  • Becker, Tanja; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Cellular Cullin RING Ubiquitin Ligases : Druggable Host Dependency Factors of Cytomegaloviruses
    In: International Journal of Molecular Sciences (IJMS) , Jg. 20 2019 , Nr. 7 , S. 1636
    DOI, Online Volltext (Open Access)
  • Zimmermann, Cosima; Kowalewski, Daniel; Bauersfeld, Liane; Hildenbrand, Andreas; Gerke, Carolin; Schwarzmüller, Magdalena; Le-Trilling, Vu Thuy Khanh; Stevanovic, Stefan; Hengel, Hartmut; Momburg, Frank; Halenius, Anne
    HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11
    In: PLoS Pathogens , Jg. 15 2019 , Nr. 9 , S. e1008040
    DOI (Open Access)
  • Bongard, Nadine; Le-Trilling, Vu Thuy Khanh; Malyshkina, Anna; Rückborn, Meike; Wohlgemuth, Kerstin; Wensing, Ina; Windmann, Sonja; Dittmer, Ulf; Trilling, Mirko; Bayer, Wibke
    Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection
    In: PLoS Pathogens , Jg. 15 2019 , Nr. 9 , e1008043
    DOI (Open Access)
  • Winkler, Roni; Gillis, Ella; Lasman, Lior; Safra, Modi; Geula, Shay; Soyris, Clara; Nachshon, Aharon; Tai-Schmiedel, Julie; Friedman, Nehemya; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Mandelboim, Michal; Hanna, Jacob H.; Schwartz, Schraga; Stern-Ginossar, Noam
    Publisher Correction : m6A modification controls the innate immune response to infection by targeting type I interferons
    In: Nature Immunology , Jg. 20 2019 , Nr. 2 , S. 243
    DOI (Open Access)
  • Winkler, Roni; Gillis, Ella; Lasman, Lior; Safra, Modi; Geula, Shay; Soyris, Clara; Nachshon, Aharon; Tai-Schmiedel, Julie; Friedman, Nehemya; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Mandelboim, Michal; Hanna, Jacob H.; Schwartz, Schraga; Stern-Ginossar, Noam
    m⁶A modification controls the innate immune response to infection by targeting type I interferons
    In: Nature Immunology , Jg. 20 2019 , S. 173 - 183
    DOI
  • Landsberg, Christine D.; Megger, Dominik A.; Hotter, Dominik; Rückborn, Meike U.; Eilbrecht, Mareike; Rashidi-Alavijeh, Jassin; Howe, Sebastian; Heinrichs, Stefan; Sauter, Daniel; Sitek, Barbara; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx
    In: Frontiers in Immunology , Jg. 9 2018 , S. 2978
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Wohlgemuth, Kerstin; Rückborn, Meike U.; Jagnjic, Andreja; Maaßen, Fabienne; Timmer, Lejla; Katschinski, Benjamin; Trilling, Mirko
    STAT2-Dependent immune responses ensure host survival despite the presence of a potent viral antagonist
    In: Journal of Virology , Jg. 92 2018 , Nr. 14 , S. e00296 - 18.
    DOI (Open Access)
  • Rohn, Hana; Tomoya Michita, Rafael; Schwich, Esther; Dolff, Sebastian; Gäckler, Anja; Horn, Peter; Kribben, Andreas; Trilling, Mirko; Le-Trilling, Vu Thuy Khanh; Wilde, Benjamin; Korth, Johannes; Heinemann, Falko M.; Witzke, Oliver; Rebmann, Vera
    The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients
    In: Frontiers in Immunology , Jg. 9 2018 , S. 917
    DOI, Online Volltext (Open Access)
  • Dassa, Liat; Seidel, Einat; Oiknine-Djian, Esther; Yamin, Rachel; Wolf, Dana G.; Le-Trilling, Vu Thuy Khanh; Mandelboim, Ofer
    The human cytomegalovirus protein UL148A downregulates the NK cell-activating ligand MICA to avoid NK cell attack
    In: Journal of Virology , Jg. 92 2018 , Nr. 17 , S. e00162 - 18
    DOI (Open Access)
  • Megger, Dominik A; Philipp, Jos; Le-Trilling, Vu Thuy Khanh; Sitek, Barbara; Trilling, Mirko
    Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.
    In: Frontiers in Immunology , Jg. 14 2017 , Nr. 8 , 1139
    DOI (Open Access)
  • Grosche, Linda; Draßner, Christina; Mühl-Zürbes, Petra; Kamm, Lisa; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Steinkasserer, Alexander; Heilingloh, Christiane S.
    Human cytomegalovirus-induced degradation of CYTIP modulates dendritic cell adhesion and migration
    In: Frontiers in Immunology , Jg. 8 2017 , 461
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture system
    In: PLoS ONE , Jg. 12 2017 , Nr. 3 , e0174695
    DOI (Open Access)
  • Schupp, Anna-Kathrin; Trilling, Mirko; Rattay, Stephanie; Le-Trilling, Vu Thuy Khanh; Haselow, Katrin; Stindt, Jan; Zimmermann, Albert; Häussinger, Dieter; Hengel, Hartmut; Graf, Dirk
    Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in Hepatocytes
    In: Journal of Virology , Jg. 90 2016 , Nr. 15 , S. 6686 - 6698
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Megger, Dominik A.; Katschinski, Benjamin; Landsberg, Christine D.; Rückborn, Meike U.; Tao, Sha; Krawczyk, Adalbert; Bayer, Wibke; Drexler, Ingo; Tenbusch, Matthias; Sitek, Barbara; Trilling, Mirko
    Broad and potent antiviral activity of the NAE inhibitor MLN4924
    In: Scientific Reports , Jg. 6 2016 , 19977
    DOI (Open Access)
  • Yamin, Rachel; Lecker, Laura S.M.; Weisblum, Yiska; Vitenshtein, Alon; Le-Trilling, Vu Thuy Khanh; Wolf, Dana G.; Mandelboim, Ofer
    HCMV vCXCL1 Binds Several Chemokine Receptors and Preferentially Attracts Neutrophils over NK Cells by Interacting with CXCR2
    In: Cell Reports , Jg. 15 2016 , Nr. 7 , S. 1542 - 1553
    DOI (Open Access)
  • Ehlting, Christian; Trilling, Mirko; Tiedje, Christopher; Le-Trilling, Vu Thuy Khanh; Albrecht, Ute; Kluge, Stefanie; Zimmermann, Albert; Graf, Dirk; Gaestel, Matthias; Hengel, Hartmut; Häussinger, Dieter; Bode, Johannes Georg
    MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infections
    In: Journal of Hepatology , Jg. 64 2016 , Nr. 2 , S. 380 - 389
    DOI
  • Donnarumma, Tiziano; Young, George R; Merkenschlager, Julia; Eksmond, Urszula; Bongard, Nadine; Nutt, Stephen L; Boyer, Claude; Dittmer, Ulf; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Bayer, Wibke; Kassiotis, George
    Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus
    In: Cell Reports , Jg. 17 2016 , Nr. 6 , S. 1571 - 1583
    DOI (Open Access)
  • Le-Trilling, Vu Thuy Khanh; Trilling, Mirko
    Attack, parry and riposte : Molecular fencing between the innate immune system and human herpesviruses
    In: Tissue Antigens , Jg. 86 2015 , Nr. 1 , S. 1 - 13
    DOI
  • Seidel, Einat; Le, Vu Thuy Khanh; Bar-On, Yotam; Tsukerman, Pinchas; Enk, Jonatan; Yamin, Rachel; Stein, Nathan; Schmiedel, Dominik; Djian, Esther Oiknine; Weisblum, Yiska; Tirosh, Boaz; Stastny, Peter; Wolf, Dana G.; Hengel, Hartmut; Mandelboim, Ofer
    Dynamic co-evolution of host and pathogen : HCMV downregulates the prevalent allele MICA*008 to escape elimination by NK cells
    In: Cell Reports , Jg. 10 2015 , Nr. 6 , S. 968 - 982
    DOI (Open Access)
  • Rattay, Stephanie; Trilling, Mirko; Megger, Dominik A.; Sitek, Barbara; Meyer, Helmut E.; Hengel, Hartmut; Le-Trilling, Vu Thuy Khanh
    The canonical immediate early 3 gene product pIE611 of mouse cytomegalovirus is dispensable for viral replication but mediates transcriptional and posttranscriptional regulation of viral gene products
    In: Journal of Virology , Jg. 89 2015 , Nr. 16 , S. 8590 - 8598
    DOI (Open Access)
  • Tirosh, Osnat; Cohen, Yifat; Shitrit, Alina; Shani, Odem; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Friedlander, Gilgi; Tanenbaum, Marvin; Stern-Ginossar, Noam
    The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactions
    In: PLoS Pathogens , Jg. 11 2015 , Nr. 11 , e1005288
    DOI (Open Access)
  • Trilling, Mirko; Le, Vu Thuy Khanh; Rashidi-Alavijeh, Jassin; Katschinski, Benjamin; Scheller, Jürgen; Rose-John, Stefan; Androsiac, Gabriela Elena; Jonjic, Stipan; Poli, Valeria; Pfeffer, Klaus; Hengel, Hartmut
    "Activated" STAT proteins : a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells
    In: The Journal of Immunology (JI) , Jg. 192 2014 , Nr. 1 , S. 447 - 458
    DOI (Open Access)
  • Zimmermann, Albert; Hauka, Sebastian; Maywald, Marco; Le, Vu Thuy Khanh; Schmidt, Silvia K.; Däubener, Walter; Hengel, Hartmut
    Checks and balances between human cytomegalovirus replication and indoleamine-2,3- dioxygenase
    In: Journal of General Virology , Jg. 95 2014 , S. 659 - 670
    DOI
  • Corrales-Aguilar, Eugenia; Trilling, Mirko; Hunold, Katja; Fiedler, Manuela; Le, Vu Thuy Khanh; Reinhard, Henrike; Ehrhardt, Katrin; Mercé-Maldonado, Eva; Aliyev, Enver; Zimmermann, Albert; Johnson, David C; Hengel, Hartmut
    Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III
    In: PLoS Pathogens , Jg. 10 2014 , Nr. 5 , e1004131
    DOI (Open Access)
  • Rölle, Alexander; Pollmann, Julia; Ewen, Eva Maria; Le, Vu Thuy Khanh; Halenius, Anne; Hengel, Hartmut; Cerwenka, Adelheid
    IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion
    In: The Journal of Clinical Investigation (JCI) , Jg. 124 2014 , Nr. 12 , S. 5305 - 5316
    DOI
  • Nachmani, Daphna; Zimmermann, Albert; Oiknine Dijan, Esther; Weisblum, Yiska; Livneh, Yoav; Le, Vu Thuy Khanh; Galun, Eithan; Horejsi, Vaclav; Isakov, Ofer; Shomron, Noam; Wolf, Dana G.; Hengel, Hartmut; Mandelboim, Ofer
    MicroRNA Editing Facilitates Immune Elimination of HCMV Infected Cells
    In: PLoS Pathogens , Jg. 10 2014 , Nr. 2 , e1003963
    DOI (Open Access)
  • Trilling, Mirko; Le, Vu Thuy Khanh; Hengel, Hartmut
    Interplay between CMVs and interferon signaling : Implications for pathogenesis and therapeutic intervention
    In: Future Microbiology , Jg. 7 2012 , Nr. 11 , S. 1269 - 1282
    DOI

    • Abstracts

  • Schoeler, Lara; Le-Trilling, Vu Thuy Khanh; Dittmer, Ulf; Esser, Stefan; Trilling, Mirko; HIV HEART AGEING Study
    Analyses of defined human cytomegalovirus-specific antibody effector functions in people living with human immunodeficiency virus
    DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,
    In: HIV Medicine , Jg. 24 2023 , Nr. 1 , S. 48 - 49

    • Poster / Posterbeiträge

  • Pfeifer, Kai Robin; Ebel, Jana-Fabienne; Trilling, Mirko; Le-Trilling, Vu Thuy Khanh; Westendorf, Astrid
    Cytomegalovirus infection aggravates intestinal inflammation during colitis and impairs the convalescence of the intestinal niche
    Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,
    In: European Journal of Immunology , Jg. 53 2023 , Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France , S. 354
    DOI (Open Access)
  • Grosche, L.; Drassner, C.; Muehl-Zuerbes, P.; Kamm, L.; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Steinkasserer, A.; Heilingloh, C.
    Human cytomegalovirus interferes with dendritic cell adhesion and migration via the proteasomal degradation of the cytohesin-1 interacting protein
    15th International Symposium on Dendritic Cells, 10–14 June 2018, Aachen, Germany,
    In: European Journal of Immunology , Jg. 48 2018 , Nr. Suppl. 1 , S. 103 - 104
    DOI (Open Access)