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Wiss. Mitarbeiter/in und Wiss. Assistent/in, Institut für Virologie
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WiSe 2024
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furinIn: Virus Research , Jg. 350 2024 , 199485DOI (Open Access)
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Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterningIn: eLife , Jg. 13 2024 , e85560DOI (Open Access)
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UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an exampleIn: BMC Genomics , Jg. 25 2024 , Nr. 1 , 647DOI, Online Volltext (Open Access)
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A simple algorithm based on initial Ct values predicts the duration to SARS-CoV-2 negativity and allows more efficient test-to-release and return-to-work schedulesIn: Diagnostic Microbiology and Infectious Disease , Jg. 106 2023 , Nr. 3 , 115949DOI (Open Access)
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Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cellsIn: European Journal of Immunology , Jg. 53 2023 , Nr. 2 , 2249940DOI (Open Access)
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Antibody responses elicited by mRNA vaccination in firefighters persist six months and correlate inversely with age and directly with BMIIn: Heliyon , Jg. 9 2023 , Nr. 1 , e12746DOI, Online Volltext (Open Access)
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Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulationIn: Frontiers in Immunology , Jg. 14 2023 , 1170300DOI, Online Volltext (Open Access)
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Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirusIn: npj Vaccines , Jg. 8 2023 , Nr. 1 , 8DOI, Online Volltext (Open Access)
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Persistence of KIRⁿeg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivationIn: Frontiers in Immunology , Jg. 14 2023 , 1266051DOI (Open Access)
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SARS-CoV-2 particles promote airway epithelial differentiation and ciliationIn: Frontiers in Bioengineering and Biotechnology , Jg. 11 2023 , 1268782DOI (Open Access)
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Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptorIn: The EMBO Journal , Jg. 42 2023 , Nr. 5 , e112351DOI (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio , Jg. 14 2023 , Nr. 6 , e02357-23DOI, Online Volltext (Open Access)
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Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infectionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) , Jg. 119 2022 , Nr. 8 , e2111600119DOI (Open Access)
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Discrepancy between frequent occurrence of COVID-19-like symptoms and low seroconversion rates among healthcare workersIn: Journal of Medical Virology , Jg. 94 2022 , Nr. 3: Special Issue on New coronavirus (2019‐nCoV or SARS‐CoV‐2) and the outbreak of the respiratory illness (COVID‐19): Part‐XVIII , S. 951 - 957DOI (Open Access)
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Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies virus neutralizing antibodiesIn: PLoS Neglected Tropical Diseases , Jg. 16 2022 , Nr. 5 , e0010425DOI, Online Volltext (Open Access)
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Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitroIn: BMC Biology (incorporating Journal of Biology) , Jg. 20 2022 , Nr. 1 , 264DOI, Online Volltext (Open Access)
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Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitroIn: Emerging Microbes & Infections , Jg. 11 2022 , Nr. 1 , S. 483 - 497DOI (Open Access)
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A rapid test recognizing mucosal SARS-CoV-2-specific antibodies distinguishes prodromal from convalescent COVID-19In: iScience , Jg. 24 2021 , Nr. 10 , 103194DOI (Open Access)
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Human cytomegalovirus antagonizes activation of fcγ receptors by distinct and synergizing modes of igg manipulationIn: eLife , Jg. 10 2021 , S. e63877DOI (Open Access)
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Nedd8-activating enzyme is a druggable host dependency factor of human and mouse cytomegalovirusIn: Viruses , Jg. 13 2021 , Nr. 8 , 1610DOI, Online Volltext (Open Access)
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Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral ImmunityIn: Frontiers in Immunology , Jg. 12 2021 , 722027DOI, Online Volltext (Open Access)
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Over 90% of clinical swabs used for SARS-CoV-2 diagnostics contain sufficient nucleic acid concentrationsIn: Journal of Medical Virology , Jg. 93 2021 , Nr. 5 , S. 2848 - 2856DOI (Open Access)
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Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist in miceIn: European Journal of Immunology , Jg. 51 2021 , Nr. 2 , S. 393 - 407DOI (Open Access)
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Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCTIn: JCI Insight , Jg. 6 2021 , Nr. 12 , e146973DOI (Open Access)
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The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele : MICA*008, to evade NK cell-mediated killingIn: PLoS Pathogens , Jg. 17 2021 , Nr. 5 , S. e1008807DOI (Open Access)
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Turmeric root and its bioactive ingredient curcumin effectively neutralize sars-cov-2 in vitroIn: Viruses , Jg. 13 2021 , Nr. 10 , 1914DOI, Online Volltext (Open Access)
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A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral CompoundsIn: Frontiers in Immunology , Jg. 11 2020 , S. 573526DOI, Online Volltext (Open Access)
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Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion modelsIn: Journal of Experimental Medicine (JEM) , Jg. 217 2020 , Nr. 3 , S. e20191164DOI (Open Access)
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Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral ReplicationIn: Frontiers in Cellular and Infection Microbiology , Jg. 10 2020 , 171DOI, Online Volltext (Open Access)
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Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapyIn: The Journal of Clinical Investigation (JCI) , Jg. 130 2020 , Nr. 8 , S. 4266 - 4281DOI (Open Access)
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The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate ImmunityIn: Cell Reports , Jg. 30 2020 , Nr. 7 , S. 2248 - 2260.e5DOI (Open Access)
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Ub to no good : How cytomegaloviruses exploit the ubiquitin proteasome systemIn: Virus Research , Jg. 281 2020 , S. 197938
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Cellular Cullin RING Ubiquitin Ligases : Druggable Host Dependency Factors of CytomegalovirusesIn: International Journal of Molecular Sciences (IJMS) , Jg. 20 2019 , Nr. 7 , S. 1636DOI, Online Volltext (Open Access)
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HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11In: PLoS Pathogens , Jg. 15 2019 , Nr. 9 , S. e1008040DOI (Open Access)
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Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infectionIn: PLoS Pathogens , Jg. 15 2019 , Nr. 9 , e1008043DOI (Open Access)
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Publisher Correction : m6A modification controls the innate immune response to infection by targeting type I interferonsIn: Nature Immunology , Jg. 20 2019 , Nr. 2 , S. 243DOI (Open Access)
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m⁶A modification controls the innate immune response to infection by targeting type I interferonsIn: Nature Immunology , Jg. 20 2019 , S. 173 - 183
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A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded VpxIn: Frontiers in Immunology , Jg. 9 2018 , S. 2978DOI (Open Access)
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STAT2-Dependent immune responses ensure host survival despite the presence of a potent viral antagonistIn: Journal of Virology , Jg. 92 2018 , Nr. 14 , S. e00296 - 18.DOI (Open Access)
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The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant RecipientsIn: Frontiers in Immunology , Jg. 9 2018 , S. 917DOI, Online Volltext (Open Access)
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The human cytomegalovirus protein UL148A downregulates the NK cell-activating ligand MICA to avoid NK cell attackIn: Journal of Virology , Jg. 92 2018 , Nr. 17 , S. e00162 - 18DOI (Open Access)
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Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.In: Frontiers in Immunology , Jg. 14 2017 , Nr. 8 , 1139DOI (Open Access)
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Human cytomegalovirus-induced degradation of CYTIP modulates dendritic cell adhesion and migrationIn: Frontiers in Immunology , Jg. 8 2017 , 461DOI (Open Access)
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Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture systemIn: PLoS ONE , Jg. 12 2017 , Nr. 3 , e0174695DOI (Open Access)
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Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in HepatocytesIn: Journal of Virology , Jg. 90 2016 , Nr. 15 , S. 6686 - 6698DOI (Open Access)
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Broad and potent antiviral activity of the NAE inhibitor MLN4924In: Scientific Reports , Jg. 6 2016 , 19977DOI (Open Access)
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HCMV vCXCL1 Binds Several Chemokine Receptors and Preferentially Attracts Neutrophils over NK Cells by Interacting with CXCR2In: Cell Reports , Jg. 15 2016 , Nr. 7 , S. 1542 - 1553DOI (Open Access)
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MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infectionsIn: Journal of Hepatology , Jg. 64 2016 , Nr. 2 , S. 380 - 389
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Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 NexusIn: Cell Reports , Jg. 17 2016 , Nr. 6 , S. 1571 - 1583DOI (Open Access)
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Attack, parry and riposte : Molecular fencing between the innate immune system and human herpesvirusesIn: Tissue Antigens , Jg. 86 2015 , Nr. 1 , S. 1 - 13
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Dynamic co-evolution of host and pathogen : HCMV downregulates the prevalent allele MICA*008 to escape elimination by NK cellsIn: Cell Reports , Jg. 10 2015 , Nr. 6 , S. 968 - 982DOI (Open Access)
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The canonical immediate early 3 gene product pIE611 of mouse cytomegalovirus is dispensable for viral replication but mediates transcriptional and posttranscriptional regulation of viral gene productsIn: Journal of Virology , Jg. 89 2015 , Nr. 16 , S. 8590 - 8598DOI (Open Access)
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The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactionsIn: PLoS Pathogens , Jg. 11 2015 , Nr. 11 , e1005288DOI (Open Access)
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"Activated" STAT proteins : a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cellsIn: The Journal of Immunology (JI) , Jg. 192 2014 , Nr. 1 , S. 447 - 458DOI (Open Access)
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Checks and balances between human cytomegalovirus replication and indoleamine-2,3- dioxygenaseIn: Journal of General Virology , Jg. 95 2014 , S. 659 - 670
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Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and IIIIn: PLoS Pathogens , Jg. 10 2014 , Nr. 5 , e1004131DOI (Open Access)
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IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansionIn: The Journal of Clinical Investigation (JCI) , Jg. 124 2014 , Nr. 12 , S. 5305 - 5316
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MicroRNA Editing Facilitates Immune Elimination of HCMV Infected CellsIn: PLoS Pathogens , Jg. 10 2014 , Nr. 2 , e1003963DOI (Open Access)
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Interplay between CMVs and interferon signaling : Implications for pathogenesis and therapeutic interventionIn: Future Microbiology , Jg. 7 2012 , Nr. 11 , S. 1269 - 1282
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Analyses of defined human cytomegalovirus-specific antibody effector functions in people living with human immunodeficiency virus
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine , Jg. 24 2023 , Nr. 1 , S. 48 - 49 -
Cytomegalovirus infection aggravates intestinal inflammation during colitis and impairs the convalescence of the intestinal niche
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology , Jg. 53 2023 , Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France , S. 354DOI (Open Access) -
Human cytomegalovirus interferes with dendritic cell adhesion and migration via the proteasomal degradation of the cytohesin-1 interacting protein
15th International Symposium on Dendritic Cells, 10–14 June 2018, Aachen, Germany,In: European Journal of Immunology , Jg. 48 2018 , Nr. Suppl. 1 , S. 103 - 104DOI (Open Access)