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Wissenschaftliche/r Mitarbeiter/in, Institut für Virologie
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2024 WS
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2024 SS
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2023 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Divergent autoantibody and cytokine levels in COVID-19 sepsis patients influence survivalIn: Journal of Medical Virology Jg. 96 (2024) Nr. 10, e29935Online Volltext: dx.doi.org/ (Open Access)
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IFNα Subtypes in HIV Infection and ImmunityIn: Viruses Jg. 16 (2024) Nr. 3, 364Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Identification of nitrile-containing isoquinoline-related natural product derivatives as coronavirus entry inhibitors in silico and in vitroIn: Biomedicine & Pharmacotherapy Jg. 180 (2024) 117517Online Volltext: dx.doi.org/ (Open Access)
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Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour controlIn: PLoS Pathogens Jg. 20 (2024) Nr. 1, e1011982Online Volltext: dx.doi.org/ (Open Access)
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Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cellsIn: Cell Reports Medicine Jg. 5 (2024) Nr. 4, 101483Online Volltext: dx.doi.org/ (Open Access)
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Reduced vacuolar ATPase protects mice from Friend virus infection – an unintended but instructive effect in Hif-2afl miceIn: Journal of Cell Science Jg. 137 (2024) Nr. 12, jcs261893Online Volltext: dx.doi.org/
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The interferon-regulated host factor hnRNPA0 modulates HIV-1 production by interference with LTR activity, mRNA trafficking, and programmed ribosomal frameshiftingIn: Journal of Virology Jg. 98 (2024) Nr. 7, e0053424Online Volltext: dx.doi.org/
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A systematic comparison reveals dynamic differences in early adaptive immune responses of acute-resolving versus chronic HBV replicationIn: Journal of Medical Virology Jg. 95 (2023) Nr. 3, e28670Online Volltext: dx.doi.org/ (Open Access)
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Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell folliclesIn: PLoS Pathogens Jg. 19 (2023) Nr. 10, e1011725Online Volltext: dx.doi.org/ (Open Access)
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Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patientsIn: Frontiers in Immunology Jg. 14 (2023) 1236374Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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SARS-CoV-2-specific T cell responses wane profoundly in convalescent individuals 10 months after primary infectionIn: Virologica Sinica Jg. 38 (2023) Nr. 4, S. 606 - 619Online Volltext: dx.doi.org/ (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio Jg. 14 (2023) Nr. 6, e02357-23Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitisIn: Scientific Reports Jg. 13 (2023) Nr. 1, 22829Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A ribavirin-induced ORF2 single-nucleotide variant produces defective hepatitis E virus particles with immune decoy functionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 119 (2022) Nr. 34, e2202653119Online Volltext: dx.doi.org/ (Open Access)
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CD47 restricts antiviral function of alveolar macrophages during influenza virus infectionIn: iScience Jg. 25 (2022) Nr. 12, 105540Online Volltext: dx.doi.org/
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Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infectionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 119 (2022) Nr. 8, e2111600119Online Volltext: dx.doi.org/ (Open Access)
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Distinct Type I Interferon Subtypes Differentially Stimulate T Cell Responses in HIV-1-Infected IndividualsIn: Frontiers in Immunology Jg. 13 (2022) 936918Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Distinct effects of treatment with two different interferon-alpha subtypes on HIV-1-associated T-cell activation and dysfunction in humanized miceIn: AIDS Jg. 36 (2022) Nr. 3, S. 325 - 336Online Volltext: dx.doi.org/
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IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph NodesIn: Frontiers in Immunology Jg. 13 (2022)Online Volltext: dx.doi.org/ (Open Access)
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IFNα subtype-specific susceptibility of HBV in the course of chronic infectionIn: Frontiers in Immunology Jg. 13 (2022) 1017753Online Volltext: dx.doi.org/ (Open Access)
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Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral InfectionIn: Frontiers in Immunology Jg. 12 (2022) 809774Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration stepsIn: Frontiers in Immunology Jg. 13 (2022) 935800Online Volltext: dx.doi.org/ (Open Access)
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Superior antiviral activity of IFNβ in genital HSV-1 infectionIn: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022) 949036Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral ActivityIn: Viruses Jg. 14 (2022) Nr. 9, 2031Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell ResponsesIn: Frontiers in Virology Jg. 2 (2022) 836291Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairmentIn: mBio Jg. 12 (2021) Nr. 2, S. e00085 - 21Online Volltext: dx.doi.org/ (Open Access)
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Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World SettingIn: Frontiers in Immunology Jg. 12 (2021) 802858Online Volltext: dx.doi.org/ (Open Access)
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Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ SignalingIn: Hepatology Jg. 73 (2021) Nr. 2, S. 486 - 502Online Volltext: dx.doi.org/
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Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg lossIn: EBioMedicine Jg. 69 (2021) 103464Online Volltext: dx.doi.org/ (Open Access)
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TLR4 Transactivates CD8⁺ T Lymphocytes upon Acute Sterile Tissue InjuryIn: ImmunoHorizons Jg. 5 (2021) Nr. 5, S. 298 - 306Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A Crowned Killer’s Résumé : Genome, Structure, Receptors, and Origin of SARS-CoV-2In: Virologica Sinica (2020)Online Volltext: dx.doi.org/ (Open Access)
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Die Einmischer: Interferone : Wie sie die Immunantwort beeinflussen, um Viren effektiv zu bekämpfenIn: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 18 - 27Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Erratum for Westmeier et al., "Impaired Cytotoxic CD8⁺ T Cell Response in Elderly COVID-19 Patients"In: mBio Jg. 11 (2020) Nr. 5, S. 02243 - 02220Online Volltext: dx.doi.org/ (Open Access)
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HIV infection does not alter interferon α/β receptor 2 expression on mucosal immune cellsIn: PLoS ONE Jg. 15 (2020) Nr. 1, S. e0218905Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Impaired cytotoxic CD8⁺ T cell response in elderly COVID-19 patientsIn: mBio Jg. 11 (2020) Nr. 5, S. e02243 - 20Online Volltext: dx.doi.org/ (Open Access)
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Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoVIn: Journal of Medical Virology Jg. 92 (2020) Nr. 5, S. 491 - 494Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Qualitative differences between the IFNα subtypes and IFNβ influence chronic mucosal HIV-1 pathogenesisIn: PLoS Pathogens Jg. 16 (2020) Nr. 10, S. 1008986Online Volltext: dx.doi.org/ (Open Access)
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SERINC5 Is an Unconventional HIV Restriction Factor That Is Upregulated during Myeloid Cell DifferentiationIn: Journal of Innate Immunity Jg. 12 (2020) Nr. 5, S. 399 - 409Online Volltext: dx.doi.org/ (Open Access)
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Susceptibility of SARS-CoV-2 to UV irradiationIn: American Journal of Infection Control Jg. 48 (2020) Nr. 10, S. 1273 - 1275Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activitiesIn: Emerging Microbes & Infections Jg. 8 (2019) Nr. 1, S. 1763 - 1776Online Volltext: dx.doi.org/ (Open Access)
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Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 FactorIn: Journal of Virology Jg. 93 (2019) Nr. 24, S. e01221 - 19Online Volltext: dx.doi.org/ (Open Access)
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Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillanceIn: Cancer Immunology, Immunotherapy Jg. 68 (2019) Nr. 3, S. 479 - 488Online Volltext: dx.doi.org/
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Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoirIn: Scientific Reports Jg. 9 (2019) S. 18089Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Different Biological Activities of Specific Interferon Alpha SubtypesIn: mSphere Jg. 4 (2019) Nr. 4, e00127 - 19Online Volltext: dx.doi.org/ (Open Access)
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Diverse immunomodulatory effects of individual IFNα subtypes on virus-specific CD8⁺ T cell responsesIn: Frontiers in Immunology Jg. 10 (2019) 2255Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunityIn: FEMS Microbiology Reviews Jg. 43 (2019) Nr. 5, S. 435 - 456Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope ProteinsIn: Cell Reports Jg. 27 (2019) Nr. 7, S. 2092 - 2104.e10Online Volltext: dx.doi.org/ (Open Access)
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PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic miceIn: Antiviral Research Jg. 161 (2019) S. 134 - 143Online Volltext: dx.doi.org/
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Plasmacytoid dendritic cells respond to Epstein-Barr virus infection with a distinct type I interferon subtype profileIn: Blood Advances Jg. 3 (2019) Nr. 7, S. 1129 - 1144Online Volltext: dx.doi.org/ (Open Access)
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An advanced BLT-humanized mouse model for extended HIV-1 cure studiesIn: AIDS Jg. 32 (2018) Nr. 1, S. 1 - 10Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotypeIn: Hepatology Jg. 67 (2018) Nr. 4, S. 1237 - 1252Online Volltext: dx.doi.org/ (Open Access)
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Impact of immune suppressive agents on the BK-Polyomavirus non coding control regionIn: Antiviral Research Jg. 159 (2018) S. 68 - 76Online Volltext: dx.doi.org/
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Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral InfectionIn: Frontiers in Immunology Jg. 9 (2018) 614Online Volltext: dx.doi.org/ (Open Access)
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Interferon α subtypes in HIV infectionIn: Cytokine & Growth Factor Reviews Jg. 40 (2018) S. 13 - 18Online Volltext: dx.doi.org/
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Different antiviral effects of IFNα and IFNβ in an HBV mouse modelIn: Immunobiology Jg. 222 (2017) Nr. 3, S. 562 - 570Online Volltext: dx.doi.org/
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Different antiviral effects of IFNα subtypes in a mouse model of HBV infectionIn: Scientific Reports Jg. 7 (2017) Nr. 1, S. 334Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Expression pattern of individual IFNA subtypes in chronic HIV infectionIn: Journal of Interferon & Cytokine Research Jg. 37 (2017) Nr. 12, S. 541 - 549Online Volltext: dx.doi.org/
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Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infectionIn: Scientific Reports Jg. 7 (2017) S. 7785Online Volltext: dx.doi.org/ (Open Access)
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Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expressionIn: European Journal of Immunology Jg. 47 (2017) Nr. 2, S. 251 - 256Online Volltext: dx.doi.org/
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Hypoxia-inducible factor 1α is essential for macrophage-mediated erythroblast proliferation in acute friend retrovirus infectionIn: Scientific Reports Jg. 7 (2017) art. no. 17236Online Volltext: dx.doi.org/ (Open Access)
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Inhibition of catecholamine degradation ameliorates while chemical sympathectomy aggravates the severity of acute Friend retrovirus infection in miceIn: Brain, Behavior and Immunity Jg. 54 (2016) S. 252 - 259Online Volltext: dx.doi.org/
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Insufficient natural killer cell responses against retroviruses : How to improve NK cell killing of retrovirus-infected cellsIn: Retrovirology Jg. 13 (2016) Nr. 1, 77Online Volltext: dx.doi.org/ (Open Access)
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Interferon alpha subtype-specific suppression of HIV-1 infection in vivoIn: Journal of Virology Jg. 90 (2016) Nr. 13, S. 6001 - 6013Online Volltext: dx.doi.org/ (Open Access)
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Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infectionIn: Retrovirology Jg. 12 (2015) Nr. 1, 66Online Volltext: dx.doi.org/ (Open Access)
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Interferon-α subtypes in an ex vivo model of acute HIV-1 infection : expression, potency and effector mechanismsIn: PLoS Pathogens Jg. 11 (2015) Nr. 11, S. e1005254Online Volltext: dx.doi.org/ (Open Access)
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TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infectionIn: Scientific Reports Jg. 5 (2015) S. 10501Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitroIn: International Immunology Jg. 26 (2014) Nr. 1, S. 35 - 46Online Volltext: dx.doi.org/
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Distinct roles of NK cells in viral immunity during different phases of acute Friend retrovirus infectionIn: Retrovirology Jg. 10 (2013) Nr. 1, 127Online Volltext: dx.doi.org/ (Open Access)
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IFN-α subtypes : Distinct biological activities in anti-viral therapyIn: British Journal of Pharmacology (BJP) Jg. 168 (2013) Nr. 5, S. 1048 - 1058Online Volltext: dx.doi.org/ (Open Access)
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IFN-α treatment inhibits acute friend retrovirus replication primarily through the antiviral effector molecule Apobec3In: The Journal of Immunology (JI) Jg. 190 (2013) Nr. 4, S. 1583 - 1590Online Volltext: dx.doi.org/
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Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral responseIn: Cell Reports Jg. 4 (2013) Nr. 4, S. 689 - 696Online Volltext: dx.doi.org/ (Open Access)
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Role of hypoxia inducible factor-1 α for interferon synthesis in mouse dendritic cellsIn: Biological Chemistry Jg. 394 (2013) Nr. 4, S. 495 - 505Online Volltext: dx.doi.org/
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Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral InfectionIn: PLoS Pathogens Jg. 8 (2012) Nr. 8, S. e1002868Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Distinct antiviral activities of IFN-α subtypesIn: Immunotherapy Jg. 3 (2011) Nr. 7, S. 813 - 816Online Volltext: dx.doi.org/
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Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8⁺ T cells and reduces chronic retroviral set pointsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 108 (2011) Nr. 6, S. 2420 - 2425Online Volltext: dx.doi.org/ (Open Access)
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Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus ReplicationIn: The Journal of Immunology (JI) Jg. 187 (2011) Nr. 7, S. 3730 - 3737Online Volltext: dx.doi.org/
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CD40 ligand-triggered human dendritic cells mount interleukin-23 responses that are further enhanced by danger signalsIn: Molecular Immunology Jg. 47 (2010) Nr. 6, S. 1255 - 1261Online Volltext: dx.doi.org/
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Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced diseaseIn: The Journal of Immunology (JI) Jg. 185 (2010) Nr. 10, S. 6179 - 6189Online Volltext: dx.doi.org/ (Open Access)
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Distinct type I interferon subtypes differentially stimulate T cell responses in HIV1-infected individuals
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine Jg. 24 (2023) Nr. 1, S. 92 -
Effects of type I interferons on HIV latency
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine Jg. 24 (2023) Nr. S1, S. 82 -
Respiratory but not systemic viral infection induces tumour growth inhibition through CD8+T-cell activation
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 189Online Volltext: dx.doi.org/ (Open Access)