Publications

All Publications

    Journal articles

  • Peck, A.; Dadi, A.; Yavarow, Z.; Alfano, L.N.; Anderson, D.; Arkin, M.R.; Chou, T.F.; D'Ambrosio, E.S.; Diaz-Manera, J.; Dudley, J.P.; Elder, A.G.; Ghoshal, N.; Hart, C.E.; Hart, M.M.; Huryn, D.M.; Johnson, A.E.; Jones, K.B.; Kimonis, V.; Kiskinis, E.; Lee, E.B.; Lloyd, T.E.; Mapstone, M.; Martin, A.; Meyer, Hemmo; Mozaffar, T.; Onyike, C.U.; Pfeffer, G.; Pindon, A.; Raman, M.; Richard, I.; Rubinsztein, D.C.; Schiava, M.; Schütz, A.K.; Shen, P.S.; Southworth, D.R.; Staffaroni, A.M.; Taralio-Gravovac, M.; Weihl, C.C.; Yao, Q.; Ye, Y.; Peck, N.
    2024 VCP International Conference : Exploring multi-disciplinary approaches from basic science of valosin containing protein, an AAA+ ATPase protein, to the therapeutic advancement for VCP-associated multisystem proteinopathy
    In: Neurobiology of Disease, Vol. 207, 2025, 106861
    DOI (Open Access)
  • Meyer, Hemmo; Kravic, Bojana
    ATG9 assists lipid replenishment for lysosome membrane repair
    In: Developmental Cell, Vol. 60, 2025, Nr. 20, pp. 2701 – 2702
    DOI
  • Reinders, Maike; Kravic, Bojana; Gahlot, Pinki; Koska, Sandra; van den Boom, Johannes; Schulze, Nina; Levantovsky, Sophie; Kleine, Stefan; Kaiser, Markus; Kulathu, Yogesh; Behrends, Christian; Meyer, Hemmo
    ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains
    In: The EMBO Journal, Vol. 44, 2025, Nr. 18, pp. 5086 – 5111
    DOI (Open Access)
  • Banerjee, Sudakshina; Cakil, Zeyneb Vildan; Gallant, Kai; van den Boom, Johannes; Palei, Shubhendu; Meyer, Hemmo; Gersch, Malte; Summerer, Daniel
    Light-Activatable Ubiquitin for Studying Linkage-Specific Ubiquitin Chain Formation Kinetics
    In: Advanced Science, Vol. 12, 2025, Nr. 6, 2406570
    DOI (Open Access)
  • Kirupakaran, Abbna; van den Boom, Johannes; Blueggel, Mike; Beuck, Christine; Niemeyer, Felix; Hayduk, Matthias; Balszuweit, Jan; Bayer, Peter; Voskuhl, Jens; Meyer, Hemmo; Schrader, Thomas
    Molecular Tweezers Block the Functional Pore of a Protein Machine
    In: Journal of the American Chemical Society: JACS, Vol. 147, 2025, Nr. 20, pp. 16836 – 16849
    DOI (Open Access)
  • Huang, Jing; Jaekel, Andreas; van den Boom, Johannes; Podlesainski, David; Elnaggar, M.; Heuer-Jungemann, A.; Kaiser, Markus; Meyer, Hemmo; Saccà, Barbara
    A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway
    In: Nature Nanotechnology, Vol. 19, 2024, Nr. 10, pp. 1521 – 1531
    DOI (Open Access)
  • Kück, Anja; van den Boom, Johannes; Koska, Sandra; Ron, David; Meyer, Hemmo
    Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatases
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 121, 2024, Nr. 36, e2408787121
    DOI (Open Access)
  • Gahlot, Pinki; Kravic, Bojana; Rota, Giulia; van den Boom, Johannes; Levantovsky, Sophie; Schulze, Nina; Maspero, Elena; Polo, Simona; Behrends, Christian; Meyer, Hemmo
    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
    In: Molecular Cell, 2024, pp. 1556 – 1569.e10
    DOI, Online Full Text (Open Access)
  • Meyer, Hemmo; Kravic, Bojana
    The Endo-Lysosomal Damage Response
    In: Annual Review of Biochemistry, Vol. 93, 2024, Nr. 1, pp. 367 – 387
    DOI (Open Access)
  • Mirsanaye, Ann Schirin; Hoffmann, Saskia; Weisser, Melanie; Mund, Andreas; Lopez Mendez, Blanca; Typas, Dimitris; van den Boom, Johannes; Benedict, Bente; Hendriks, Ivo A.; Nielsen, Michael Lund; Meyer, Hemmo; Duxin, Julien P.; Montoya, Guillermo; Mailand, Niels
    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
    In: Nature Communications, Vol. 15, 2024, Nr. 1, 2459
    DOI (Open Access)
  • van den Boom, Johannes; Marini, Guendalina; Meyer, Hemmo; Saibil, Helen R
    Structural basis of ubiquitin-independent PP1 complex disassembly by p97
    In: The EMBO Journal, Vol. 42, 2023, Nr. 14, e113110
    DOI (Open Access)
  • Meyer, Hemmo; van den Boom, Johannes
    Targeting of client proteins to the VCP/p97/Cdc48 unfolding machine
    In: Frontiers in Molecular Biosciences, Vol. 10, 2023, 1142989
    DOI, Online Full Text (Open Access)
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications, Vol. 14, 2023, Nr. 1, 3258
    DOI, Online Full Text (Open Access)
  • Seaayfan, Elie; Nasrah, Sadiq; Quell, Lea; Kleim, Maja; Weber, Stefanie; Meyer, Hemmo; Laghmani, Kamel; Kömhoff, Martin
    MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S
    In: Cells, Vol. 11, 2022, Nr. 16, 2546
    DOI (Open Access)
  • Kravić, Bojana; Bionda, Tihana; Siebert, Alexander; Gahlot, Pinki; Levantovsky, Sophie; Behrends, Christian; Meyer, Hemmo
    Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
    In: Molecular Cell, Vol. 82, 2022, Nr. 14, pp. 2633 – 2649.e7
    DOI (Open Access)
  • Kröning, Alexander; van den Boom, Johannes; Kracht, Matthias; Kück, Anja; Meyer, Hemmo
    Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTN
    In: The Journal of Biological Chemistry (JBC), Vol. 298, 2022, Nr. 6, 101976
    DOI (Open Access)
  • Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Buitrago-Molina, Laura Elisa; Lu, Mengji; Meyer, Hemmo; Tong, Chun-Kit; Sara, Abdelfatah; Thedieck, Kathrin
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
    In: Autophagy, Vol. 17, 2021, Nr. 1, pp. 1 – 382
    DOI (Open Access)
  • van den Boom, Johannes; Kück, Anja; Kravic, Bojana; Müschenborn, Helen; Giesing, Maike; Pan, Dongqing; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Meyer, Hemmo
    Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly
    In: Nature Structural & Molecular Biology, Vol. 28, 2021, Nr. 12, pp. 964 – 971
    DOI
  • Kollenda, Sebastian; Kopp, Mathis; Wens, Jasmin; Koch, Johannes; Schulze, Nina; Papadopoulos, Chrisovalantis; Pöhler, Robert; Meyer, Hemmo; Epple, Matthias
    A pH-sensitive fluorescent protein sensor to follow the pathway of calcium phosphate nanoparticles into cells
    In: Acta Biomaterialia, Vol. 111, 2020, pp. 406 – 417
    DOI
  • Kracht, Matthias; van den Boom, Johannes; Seiler, Jonas; Kröning, Alexander; Kaschani, Farnusch; Kaiser, Markus; Meyer, Hemmo
    Protein Phosphatase-1 Complex Disassembly by p97 is Initiated through Multivalent Recognition of Catalytic and Regulatory Subunits by the p97 SEP-domain Adapters
    In: Journal of Molecular Biology (JMB), Vol. 432, 2020, Nr. 23, pp. 6061 – 6074
    DOI
  • Kravic, Bojana; Behrends, Christian; Meyer, Hemmo
    Regulation of lysosome integrity and lysophagy by the ubiquitin-conjugating enzyme UBE2QL1
    In: Autophagy, Vol. 16, 2020, Nr. 1, pp. 179 – 180
    DOI, Online Full Text (Open Access)
  • Papadopoulos, Chrisovalantis; Kravic, Bojana; Meyer, Hemmo
    Repair or Lysophagy : Dealing with Damaged Lysosomes
    In: Journal of Molecular Biology (JMB), Vol. 432, 2020, Nr. 1, pp. 231 – 239
    DOI
  • Krahn, Daniel; Heilmann, Geronimo; Vogel, Felix C. E.; Papadopoulos, Chrisovalantis; Zweerink, Susanne; Kaschani, Farnusch; Meyer, Hemmo; Rösch, Alexander; Kaiser, Markus
    Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product Family
    In: Chemistry - A European Journal, Vol. 26, 2020, Nr. 39, pp. 8524 – 8531
    DOI (Open Access)
  • Blüggel, Mike; van den Boom, Johannes; Meyer, Hemmo; Bayer, Peter; Beuck, Christine
    Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase
    In: Biomolecules, Vol. 9, 2019, Nr. 12, 876
    DOI, Online Full Text (Open Access)
  • Körver, Lisa; Papadopoulos, Chrisovalantis; Liu, Bin; Kravic, Bojana; Rota, Giulia; Brecht, Lukas; Veenendaal, Tineke; Polajnar, Mira; Blümke, Anika; Ehrmann, Michael; Klumperman, Judith; Jäättelä, Marja; Behrends, Christian; Meyer, Hemmo
    The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage
    In: EMBO Reports, 2019, pp. e48014
    DOI (Open Access)
  • Arhzaouy, Khalid; Papadopoulos, Chrisovalantis; Schulze, Nina; Pittman, Sara K.; Meyer, Hemmo; Weihl, Conrad C.
    VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle
    In: Autophagy, Vol. 15, 2019, Nr. 6, pp. 1082 – 1099
    DOI (Open Access)
  • Pöhler, Robert; Krahn, Jan; van den Boom, Johannes; Dobrynin, Grzegorz; Kaschani, Farnusch; Eggenweiler, Hans-Michael; Zenke, Frank T.; Kaiser, Markus; Meyer, Hemmo
    A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases
    In: Angewandte Chemie International Edition, Vol. 57, 2018, Nr. 6, pp. 1576 – 1580
    DOI
  • Hülsmann, Julia; Kravic, Bojana; Weith, Matthias; Gstaiger, Matthias; Aebersold, Ruedi; Collins, Ben C.; Meyer, Hemmo
    AP-SWATH reveals direct involvement of VCP/ p97 in integrated stress response signaling through facilitating CReP/PPP1R15B degradation
    In: Molecular and Cellular Proteomics (MCP), Vol. 17, 2018, Nr. 7, pp. 1295 – 1307
    DOI, Online Full Text (Open Access)
  • Weith, Matthias; Seiler, Jonas; van den Boom, Johannes; Kracht, Matthias; Hülsmann, Julia; Primorac, Ivana; Del Pino Garcia, Javier; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
    In: Molecular Cell, Vol. 72, 2018, Nr. 4, pp. 766 – 777
    DOI (Open Access)
  • van den Boom, Johannes; Meyer, Hemmo
    VCP/p97-Mediated Unfolding as a Principle in Protein Homeostasis and Signaling
    In: Molecular Cell, Vol. 69, 2018, Nr. 2, pp. 182 – 194
    DOI (Open Access)
  • Kopp, Mathis; Rotan, Olga; Papadopoulos, Chrisovalantis; Schulze, Nina; Meyer, Hemmo; Epple, Matthias
    Delivery of the autofluorescent protein R-phycoerythrin by calcium phosphate nanoparticles into four different eukaryotic cell lines (HeLa, HEK293T, MG-63, MC3T3) : Highly efficient, but leading to endolysosomal proteolysis in HeLa and MC3T3 cells
    In: PLoS ONE, Vol. 12, 2017, Nr. 6, pp. e0178260
    DOI, Online Full Text (Open Access)
  • Papadopoulos, Chrisovalantis; Meyer, Hemmo
    Detection and Clearance of Damaged Lysosomes by the Endo-Lysosomal Damage Response and Lysophagy
    In: Current Biology, Vol. 27, 2017, Nr. 24, pp. R1330 – R1341
    DOI
  • Papadopoulos, Chrisovalantis; Kirchner, Philipp; Bug, Monika; Grum, Daniel; Körver, Lisa; Schulze, Nina; Pöhler, Robert; Dressler, Alina; Fengler, Sven; Arhzaouy, Khalid; Lux, Vanda; Ehrmann, Michael; Weihl, Conrad C.; Meyer, Hemmo
    VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy
    In: The EMBO Journal, Vol. 36, 2017, Nr. 2, pp. 135 – 150
    DOI (Open Access)
  • Trusch, Franziska; Kowski, Klaus; Bravo-Rodriguez, Kenny; Beuck, Christine; Sowislok, Andrea; Wettig, Burkhard; Matena, Anja; Sánchez-García, Elsa; Meyer, Hemmo; Schrader, Thomas; Bayer, Peter
    Molecular tweezers target a protein-protein interface and thereby modulate complex formation
    In: Chemical Communications: ChemComm, Vol. 52, 2016, Nr. 98, pp. 14141 – 14144
    DOI (Open Access)
  • van den Boom, Johannes; Wolf, Markus; Weimann, Lena; Schulze, Nina; Li, Fanghua; Kaschani, Farnusch; Riemer, Anne; Zierhut, Christian; Kaiser, Markus; Iliakis, George; Funabiki, Hironori; Meyer, Hemmo
    VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair
    In: Molecular Cell, Vol. 64, 2016, Nr. 1, pp. 189 – 198
    DOI (Open Access)
  • Trusch, Franziska; Matena, Anja; Vuk, Maja; Körver, Lisa; Knævelsrud, Helene; Freemont, Paul S.; Meyer, Hemmo; Bayer, Peter
    The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97
    In: The Journal of Biological Chemistry (JBC), Vol. 290, 2015, Nr. 49, pp. 29414 – 29427
    DOI (Open Access)
  • Eiteneuer, Annika; Seiler, Jonas; Weith, Matthias; Beullens, Monique; Lesage, Bart; Krenn, Veronica; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1
    In: The EMBO Journal, Vol. 33, 2014, Nr. 22, pp. 2704 – 2720
    DOI, Online Full Text (Open Access)
  • Meyer, Hemmo; Weihl, Conrad C.
    The VCP/p97 system at a glance : connecting cellular function to disease pathogenesis
    In: Journal of Cell Science, Vol. 127, 2014, Nr. 18, pp. 3877 – 3883
    DOI
  • Riemer, Anne; Dobrynin, Grzegorz; Dressler, Alina; Bremer, Sebastian; Soni, Aashish; Iliakis, George; Meyer, Hemmo
    The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation
    In: Cell Cycle, Vol. 13, 2014, Nr. 6, pp. 919 – 927
    DOI, Online Full Text (Open Access)
  • Dressler, A.; Riemer, Anne; Dobrynin, Grzegorz; Bremer, Sebastian; Soni, A.; Iliakis, George; Meyer, Hemmo
    The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation
    In: The FEBS Journal, Vol. 281, 2014, Nr. Suppl. 1, pp. 82
    DOI
  • Ehrenhofer-Murray, Ann; Meyer, Hemmo; Nellen, Wolfgang
    Coal mining meets chromatin research: Digging for mechanisms in epigenetic control of gene expression : Report from the 43rd Annual Meeting of the German Genetics Society on "Chromatin and Epigenetics" in Essen, Germany
    In: BioEssays, Vol. 35, 2013, Nr. 2, pp. 141 – 144
    DOI
  • Kress, Elsa; Schwager, Françoise; Holtackers, René; Seiler, Jonas; Prodon, François; Zanin, Esther; Eiteneues, Annika; Toya, Mika; Sugimoto, Asako; Meyer, Hemmo; Meraladi, Patrick; Gotta, Monica
    The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A
    In: The Journal of Cell Biology (JCB), Vol. 201, 2013, Nr. 4, pp. 559 – 575
    DOI
  • Kirchner, Philipp; Bug, Monika; Meyer, Hemmo
    Ubiquitination of the n-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase
    In: The Journal of Biological Chemistry (JBC), Vol. 288, 2013, Nr. 10, pp. 7363 – 7372
    DOI
  • Bebeacua, Cecilia; Förster, Andreas; McKeown, Ciarán; Meyer, Hemmo; Zhang, Xiaodong; Freemont, Paul S.
    Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 109, 2012, pp. 1098 – 1103.
    DOI (Open Access)
  • Meyer, Hemmo; Bug, Monika; Bremer, Sebastian
    Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
    In: Nature Cell Biology, Vol. 14, 2012, Nr. 2, pp. 117 – 123
    DOI
  • Bug, Monika; Meyer, Hemmo
    Expanding into new markets – VCP/p97 in endocytosis and autophagy
    In: Journal of Structural Biology, Vol. 179, 2012, Nr. 2, pp. 78 – 82
    DOI
  • Meyer, Hemmo
    p97 complexes as signal integration hubs
    In: BMC Biology (incorporating Journal of Biology), Vol. 10, 2012, pp. 48
    DOI, Online Full Text (Open Access)
  • Dobrynin, Grzegorz; Popp, Oliver; Romer, Tina; Bremer, Sebastian; Schmitz, Michael H. A.; Gerlich, Daniel W.; Meyer, Hemmo
    Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells.
    In: Journal of Cell Science, Vol. 124, 2011, Nr. 9, pp. 1571 – 1580
    DOI
  • Ritz, Danilo; Vuk, Maja; Kirchner, Philipp; Bug, Monika; Schütz, Sabina; Hayer, Arnold; Bremer, Sebastian; Lusk, Caleb; Baloh, Robert H.; Lee, Houkeun; Glatter, Timo; Gstaiger, Matthias; Aebersold, Ruedi; Weihl, Conrad C.; Meyer, Hemmo
    Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations
    In: Nature Cell Biology, Vol. 13, 2011, Nr. 9, pp. 1116 – 1123
    DOI
  • Meerang, Mayura; Ritz, Danilo; Paliwal, Shreya; Garajova, Zuzana; Bosshard, Matthias; Mailand, Niels; Janscak, Pavel; Hübscher, Ulrich; Meyer, Hemmo; Ramadan, Kristijan
    The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
    In: Nature Cell Biology, Vol. 13, 2011, Nr. 11, pp. 1376 – 1382
    DOI
  • Meyer, Hemmo; Drozdowska, Alicja; Dobrynin, Grzegorz
    A role for Cdc48/p97 and Aurora B in controlling chromatin condensation during exit from mitosis
    In: Biochemistry and Cell Biology, Vol. 88, 2010, Nr. 1, pp. 23 – 28
    DOI
  • Hayer, Arnold; Stoeber, Miriam; Ritz, Danilo; Engel, Sabrina; Meyer, Hemmo; Helenius, Ari
    Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation
    In: The Journal of Cell Biology (JCB), Vol. 191, 2010, Nr. 3, pp. 615 – 629
    DOI
  • Meyer, Hemmo; Popp, Oliver
    Role(s) of Cdc48/p97 in mitosis
    In: Biochemical Society Transactions, Vol. 36, 2008, Nr. 1, pp. 126 – 130
  • Ramadan, Kristijan; Bruderer, Roland; Spiga, Fabio M.; Popp, Oliver; Baur, Tina; Gotta, Monica; Meyer, Hemmo
    Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
    In: Nature, Vol. 450, 2007, Nr. 7173, pp. 1258
    Online Full Text
  • Isaacson, Rivka L.; Pye, Valerie E.; Simpson, Peter; Meyer, Hemmo; Zhang, Xiaodong; Freemont, Paul S.; Matthews, Steve
    Detailed structural insights into the p97-Npl4-Ufd1 interface
    In: The Journal of Biological Chemistry (JBC), Vol. 282, 2007, Nr. 29, pp. 21361 – 21369
  • Baur, Tina; Ramadan, Kristijan; Schlundt, Andreas; Kartenbeck, Jürgen; Meyer, Hemmo
    NSF- and SNARE-mediated membrane fusion is required for nuclear envelope formation and completion of nuclear pore complex assembly in Xenopus laevis egg extracts
    In: Journal of Cell Science, Vol. 120, 2007, Nr. 16, pp. 2895 – 2903
    Online Full Text
  • Pye, Valerie E.; Beuron, Fabienne; Keetch, Catherine A.; McKeown, Ciaran; Robinson, Carol V.; Meyer, Hemmo; Zhang, Xiaodong; Freemont, Paul S.
    Structural insights into the p97-Ufd1-NpI4 complex
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 104, 2007, Nr. 2, pp. 467 – 472
    Online Full Text
  • Meyer, Hemmo
    Golgi reassembly after mitosis : The AAA family meets the ubiquitin family
    In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1744, 2005, Nr. 2, pp. 108 – 119
    DOI (Open Access)
  • Bruderer, Roland M.; Brasseur, Catherine; Meyer, Hemmo
    The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism
    In: The Journal of Biological Chemistry (JBC), Vol. 279, 2004, Nr. 48, pp. 49609 – 49616
    Online Full Text
  • Alam, Steven L; Sun, Ji; Payne, Marielle; Welch, Brett D; Blake, B Kelly; Davis, Darrell R; Meyer, Hemmo; Emr, Scott D; Sundquist, Wesley I
    Ubiquitin Interactions of NZF Zinc Fingers
    In: The EMBO Journal, Vol. 23, 2004, Nr. 7, pp. 1411 – 1421
    Online Full Text
  • Wang, Yanzhuang; Satoh, Ayano; Warren, Graham; Meyer, Hemmo
    VCIP135 acts as a deubiquitinating enzyme during p97–p47-mediated reassembly of mitotic Golgi fragments
    In: The Journal of Cell Biology (JCB), Vol. 164, 2004, Nr. 7, pp. 973 – 978
    Online Full Text
  • Ye, Yihong; Meyer, Hemmo; Rapoport, Tom A.
    Function of the p97–Ufd1–Npl4 complex in retrotranslocation from the ER to the cytosol : dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
    In: The Journal of Cell Biology (JCB), Vol. 162, 2003, Nr. 1, pp. 71 – 84
    DOI
  • Wang, Bin; Alam, Steven L.; Meyer, Hemmo; Payne, Marielle; Stemmler, Timothy L.; Davis, Darrell R.; Sundquist, Wesley I.
    Structure and Ubiquitin Interactions of the Conserved Zinc Finger Domain of Npl4
    In: The Journal of Biological Chemistry (JBC), Vol. 278, 2003, pp. 20225 – 20234
    Online Full Text
  • Cao, Kan; Nakajima, Reiko; Meyer, Hemmo; Zheng, Yixian
    The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis
    In: Cell, Vol. 115, 2003, Nr. 3, pp. 355 – 367
    Online Full Text
  • Meyer, Hemmo; Wang, Yanzhuang; Warren, Graham
    Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1–Npl4
    In: The EMBO Journal, Vol. 21, 2002, Nr. 21, pp. 5645 – 5652.
    Online Full Text
  • Hetzer, Martin; Meyer, Hemmo; Walther, Tobias C.; Bilbao-Cortes, Daniel; Warren, Graham; Mattaj, Iain W.
    Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly
    In: Nature Cell Biology, Vol. 3, 2001, Nr. 12, pp. 1086 – 1091
    Online Full Text
  • Ye, Yihong; Meyer, Hemmo; Rapoport, Tom A.
    The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
    In: Nature, Vol. 414, 2001, pp. 652 – 656
    Online Full Text
  • Meyer, Hemmo; Shorter, James G.; Seemann, Joachim; Pappin, Darryl; Warren, Graham
    A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
    In: The EMBO Journal, Vol. 19, 2000, Nr. 10, pp. 2181 – 2192
    Online Full Text
  • Zhang, Xiaodong; Shaw, Anthony; Bates, Paul A.; Newman, Richard H.; Gowen, Brent; Orlova, Elena; Gorman, Michael A.; Kondo, Hisao; Dokurno, Pawel; Lally, John; Leonard, Gordon; Meyer, Hemmo; van Heel, Marin; Freemont, Paul S.
    Structure of the AAA ATPase p97
    In: Molecular Cell, Vol. 6, 2000, Nr. 6, pp. 1473 – 1484
    DOI
  • Müller, Joyce M.; Meyer, Hemmo; Ruhrberg, Christiana; Stamp, Gordon W.; Warren, Graham; Shima, David T.
    The mouse p97 (CDC48) gene. Genomic structure, definition of transcriptional regulatory sequences, gene expression, and characterization of a pseudogene.
    In: The Journal of Biological Chemistry (JBC), Vol. 274, 1999, Nr. 15, pp. 10154 – 10162
    Online Full Text
  • Meyer, Hemmo; Kondo, Hisao; Warren, Graham
    The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97
    In: FEBS Letters, Vol. 437, 1998, Nr. 3, pp. 255 – 257
    Online Full Text