Veröffentlichungen

    2025

  • Maassen, Fabienne; Le-Trilling, Vu Thuy Khanh; Betke, Luisa; Bracht, Thilo; Siegmund, Corinna; Bayer, Malte; Katschinski, Benjamin; Belter, Antonia; Becker, Tanja; Mennerich, Denise; Voigt, Sebastian; Frappier, Lori; Sitek, Barbara; Fleischhauer, Katharina; Trilling, Mirko
    The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA
    In: eLife, Jg. 14, 2025, e96414
    DOI, Online Volltext (Open Access)
  • Kehrmann, Jan; Dostmohammadi, Alireza; Stumpf, Anna-Lena; Best, Lara; Consten, Leah; Sievert, Hannah; Maischack, Felix; Sammet, Stefanie; Albayrak-Rena, Sarah; Doerr, Ann-Kathrin; Bohlen, Katharina; von Velsen, Otgonzul; Kraiselburd, Ivana; Karsten, Christina B.; Farahpour, Farnoush; Meyer, Folker; Esser, Stefan; Buer, Jan
    Gut microbiota differences linked to weight gain and ART in people living with HIV are enterotype specific and minor compared to the large differences linked to sexual behavior
    In: Frontiers in Cellular and Infection Microbiology, Jg. 15, 2025, 1568352
    DOI, Online Volltext (Open Access)
  • Shahhamzehei, Nasim; Abdelfatah, Sara; Omer, Ejlal A.; Riedl, Max; Meesters, Christian; Schwarzer-Sperber, Hannah S.; Sutter, Kathrin; Bringmann, Gerhard; Schwarzer, Roland; Efferth, Thomas
    Diketopiperazine/piperidine alkaloid as a potential broad-spectrum coronaviral entry inhibitor identified by supercomputer-based virtual screening from a large natural product-based library
    In: Biomedicine & Pharmacotherapy, Jg. 183, 2025, 117841
    DOI (Open Access)
  • Schimmer, Simone; Sridhar, Vaasudevan; Satan, Zelal; Grebe, Anton; Saad, Mohamed; Wagner, Bernd; Kahlert, Nele; Werner, Tanja; Richter, Dana; Dittmer, Ulf; Sutter, Kathrin; Littwitz-Salomon, Elisabeth
    Iron improves the antiviral activity of NK cells
    In: Frontiers in Immunology, Jg. 15, 2025, 1526197
    DOI, Online Volltext (Open Access)
  • Fayyaz, Sharmeen; Lotke, Rishikesh; Haußmann, Isabell; Petersen, Moritz; Müller, Eva; Schwarzer-Sperber, Hannah S.; Schwarzer, Roland; Sauter, Daniel; Simon, Viviana (Hrsg.)
    Reactivation of latent HIV-1 by the glucocorticoid receptor modulator AZD9567
    In: Journal of Virology, Jg. 99, 2025, Nr. 2, e01886-24
    DOI (Open Access)

    • 2024

  • Cherneha, Maxim; Zydek, Isabel; Braß, Peer; Korth, Johannes; Jansen, Sarah; Esser, Stefan; Karsten, Christina; Meyer, Folker; Kraiselburd, Ivana; Dittmer, Ulf; Lindemann, Monika; Horn, Peter; Witzke, Oliver; Thümmler, Laura; Krawczyk, Adalbert
    Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH)
    In: Vaccines, Jg. 12, 2024, Nr. 7, 785
    DOI (Open Access)
  • Mao, Binli; Le-Trilling, Vu Thuy Khanh; Tang, Haihuan; Hu, Jie; Schmitz, Mona S.; Barbet, Kimberly; Xu, Dan; Wei, Zhen; Guo, Beinu; Mennerich, Denise; Yao, Chun; Liu, Jinxin; Li, Zhenghan; Wan, Yushun; Zhang, Xiaoyong; Wang, Kai; Tang, Ni; Yu, Zebo; Trilling, Mirko; Lin, Yong
    Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin
    In: Virus Research, Jg. 350, 2024, 199485
    DOI (Open Access)
  • Esber, Allahna L.; Colt, Suze; Jian, Ningbo; Dear, Nicole; Slike, Bonnie; Sing'oei, Valentine; Maswai, Jonah; Iroezindu, Michael; Bahemana, Emmanuel; Kibuuka, Hannah; Polyak, Christina S.; Streeck, Hendrik; Shah, Neha; Crowell, Trevor A.; Ake, Julie A.
    Persistent low-level viraemia is associated with non-infectious comorbidities in an observational cohort in four African countries
    In: Journal of the International AIDS Society, Jg. 27, 2024, Nr. 8, e26316
    DOI (Open Access)
  • Stefanie, Sammet; Koldehoff, Michael; Schenk-Westkamp, Pia; Horn, Peter; Esser, Stefan; Lindemann, Monika
    T Cell Responses against Orthopoxviruses in HIV-Positive Patients
    In: Vaccines, Jg. 12, 2024, Nr. 2, 131
    DOI (Open Access)
  • Shahhamzehei, Nasim; Abdelfatah, Sara; Schwarzer-Sperber, Hannah S.; Sutter, Kathrin; Yücer, Rümeysa; Bringmann, Gerhard; Schwarzer, Roland; Efferth, Thomas
    Identification of nitrile-containing isoquinoline-related natural product derivatives as coronavirus entry inhibitors in silico and in vitro
    In: Biomedicine & Pharmacotherapy, Jg. 180, 2024, 117517
    DOI (Open Access)
  • Appeltrath, Gwenllian A.; Parreuter, Janine; Lindemann, Monika; Klump, Hannes; Karsten, Christina B.
    An efficient ELISA protocol for measurement of SARS-CoV-2 spike-specific IgG in human plasma and serum samples
    In: MethodsX, Jg. 12, 2024, 102596
    DOI, Online Volltext (Open Access)
  • Gerke, Carolin; Bauersfeld, Liane; Schirmeister, Ivo; Mireisz, Chiara Noemi-Marie; Oberhardt, Valerie; Mery, Lea; Wu, Di; Jürges, Christopher Sebastian; Spaapen, Robbert M.; Mussolino, Claudio; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Dölken, Lars; Paster, Wolfgang; Erhard, Florian; Hofmann, Maike; Schlosser, Andreas; Hengel, Hartmut; Momburg, Frank; Halenius, Anne
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
    In: eLife, Jg. 13, 2024, e85560
    DOI (Open Access)
  • Mittermüller, Daniela; Otto, Lucas; Kilian, Annika Loredana; Schnormeier, Ann-Kathrin; Littwitz-Salomon, Elisabeth; Hasenberg, Anja; Dittmer, Ulf; Gunzer, Matthias
    PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected mice
    In: Frontiers in Immunology, Jg. 15, 2024, 1338218
    DOI, Online Volltext (Open Access)
  • Karsten, Christina B.; Buettner, Falk F.R.; Cajic, Samanta; Nehlmeier, Inga; Roshani, Berit; Klippert, Antonina; Sauermann, Ulrike; Stolte-Leeb, Nicole; Reichl, Udo; Gerardy-Schahn, Rita; Rapp, Erdmann; Stahl-Hennig, Christiane; Pöhlmann, Stefan
    Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity
    In: PLoS Pathogens, Jg. 20, 2024, Nr. 5, e1012190
    DOI (Open Access)
  • Karakoese, Zehra; Ingola, Martha; Sitek, Barbara; Dittmer, Ulf; Sutter, Kathrin
    IFNα Subtypes in HIV Infection and Immunity
    In: Viruses, Jg. 16, 2024, Nr. 3, 364
    DOI, Online Volltext (Open Access)
  • Albanese, Manuel; Chen, Hong-Ru; Gapp, Madeleine; Muenchhoff, Maximilian; Yang, Hsiu-Hui; Peterhoff, David; Hoffmann, Katja; Xiao, Qianhao; Ruhle, Adrian; Ambiel, Ina; Schneider, Stephanie; Mejías-Pérez, Ernesto; Stern, Marcel; Wratil, Paul R.; Hofmann, Katharina; Amann, Laura; Jocham, Linda; Fuchs, Thimo; Ulivi, Alessandro F.; Besson-Girard, Simon; Weidlich, Simon; Schneider, Jochen; Spinner, Christoph D.; Sutter, Kathrin; Dittmer, Ulf; Humpe, Andreas; Baumeister, Philipp; Wieser, Andreas; Rothenfusser, Simon; Bogner, Johannes; Roider, Julia; Knolle, Percy; Hengel, Hartmut; Wagner, Ralf; Laketa, Vibor; Fackler, Oliver T.; Keppler, Oliver T.
    Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells
    In: Cell Reports Medicine, Jg. 5, 2024, Nr. 4, 101483
    DOI (Open Access)
  • Thomas, Alexander; Battenfeld, Thomas; Kraiselburd, Ivana; Anastasiou, Olympia; Dittmer, Ulf; Dörr, Ann-Kathrin; Dörr, Adrian; Elsner, Carina; Gosch, Jule; Le-Trilling, Vu Thuy Khanh; Magin, Simon; Scholtysik, René; Yilmaz, Pelin; Trilling, Mirko; Schöler, Lara; Köster, Johannes; Meyer, Folker
    UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an example
    In: BMC Genomics, Jg. 25, 2024, Nr. 1, 647
    DOI, Online Volltext (Open Access)
  • Mavarani, Laven; Reinsch, Nico; Albayrak-Rena, Sarah; Potthoff, Anja; Hower, Martin; Dolff, Sebastian; Schadendorf, Dirk; Jöckel, Karl-Heinz; Schmidt, Börge; Esser, Stefan
    The Association of HIV-Specific Risk Factors with Cardiovascular Events in Addition to Traditional Risk Factors in People Living with HIV
    In: AIDS Research and Human Retroviruses, Jg. 40, 2024, Nr. 4, S. 235 – 245
    DOI

    • 2023

  • Mavarani, Laven; Albayrak-Rena, Sarah; Potthoff, Anja; Hower, Martin; Dolff, Sebastian; Sammet, Stefanie; Maischack, Felix; Schadendorf, Dirk; Schmidt, Börge; Esser, Stefan; HIV HEART AGING Study
    Changes in body mass index, weight, and waist-to-hip ratio over five years in HIV-positive individuals in the HIV Heart Aging Study compared to the general population
    In: Infection - A Journal of Infectious Disease, Jg. 51, 2023, Nr. 4, S. 1081 – 1091
    DOI (Open Access)
  • Schimmer, Simone; Mittermüller, Daniela; Werner, Tanja; Görs, Paul E.; Meckelmann, Sven; Finlay, David K.; Dittmer, Ulf; Littwitz-Salomon, Elisabeth
    Fatty acids are crucial to fuel NK cells upon acute retrovirus infection
    In: Frontiers in Immunology, Jg. 14, 2023, 1296355
    DOI, Online Volltext (Open Access)
  • Esber, Allahna L.; Streeck, Hendrik; Jansen, Klaus; Dorsey-Spitz, Julie; Robb, Merlin L.; Crowell, Trevor A.
    High hepatitis B vaccination coverage among a cohort of predominantly men who have sex with men in Germany
    In: Human Vaccines & Immunotherapeutics, Jg. 19, 2023, Nr. 2, 2238576
    DOI (Open Access)
  • Schild, Yves; Bosserhoff, Jonah; Droege, Freya; Littwitz-Salomon, Elisabeth; Fandrey, Joachim; Wrobeln, Anna
    Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor Improves Leukocyte Energy Metabolism in Hereditary Hemorrhagic Telangiectasia
    In: Life, Jg. 13, 2023, Nr. 8, 1708
    DOI, Online Volltext (Open Access)
  • Malyshkina, Anna; Bayer, Wibke; Podschwadt, Philip; Otto, Lucas; Karakoese, Zehra; Sutter, Kathrin; Bruderek, Kirsten; Wang, Baoxiao; Lavender, Kerry J.; Santiago, Mario L.; Leipe, Pia Madeleine; Elsner, Carina; Esser, Stefan; Brandau, Sven; Gunzer, Matthias; Dittmer, Ulf
    Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell follicles
    In: PLoS Pathogens, Jg. 19, 2023, Nr. 10, e1011725
    DOI (Open Access)
  • Sperber, Hannah S.; Raymond, Kyle A.; Bouzidi, Mohamed S.; Ma, Tongcui; Valdebenito, Silvana; Eugenin, Eliseo A.; Roan, Nadia R.; Deeks, Steven G.; Winning, Sandra; Fandrey, Joachim; Schwarzer, Roland; Pillai, Satish K.
    The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency
    In: Cell Reports, Jg. 42, 2023, Nr. 11, 113285
    DOI (Open Access)
  • B Narayanan, Vedha Hari; Kost, Bartłomiej; Lewandowski, Artur; Durai, Ramya Devi; Wawrzyniak, Paweł; Biela, Tadeusz; Wingenfeld, Rieke; Sabeth Sperber, Hannah; Schwarzer, Roland; Brzeziński, Marek
    PLA stereocomplex-chitosan nanoparticles loaded with tenofovir alafenamide as a long-acting antiretrovirals
    In: Advanced Powder Technology, Jg. 34, 2023, Nr. 11, 104205
    DOI
  • Esber, Allahna L.; Jansen, Klaus; Dorsey-Spitz, Julie; Robb, Merlin L.; Streeck, Hendrik; Crowell, Trevor A.
    Preparing for future European efficacy trials of interventions to prevent HIV and other sexually transmitted infections : Lessons on willingness to participate and barriers to participation from ten German clinics serving behaviorally vulnerable men who have sex with men
    In: Vaccine: X, Jg. 14, 2023, 100302
    DOI (Open Access)
  • Elsner, Carina; Appeltrath, Gwenllian A.; Konik, Margarethe; Parreuter, Janine; Bröcker-Preuß, Martina; Krawczyk, Adalbert; Esser, Stefan; Sammet, Stefanie; Karsten, Christina B.
    False-Positive Screening and Confirmatory HIV Diagnostic Test in a Patient with Cured SARS-CoV-2 Infection Is Not Mediated by Env/Spike Cross-Reactive Antibodies
    In: Viruses, Jg. 15, 2023, Nr. 5, 1161
    DOI (Open Access)
  • Mittermüller, Daniela; Otto, Lucas; Long, Zoë; Kraus, Andreas; Beer, Alexander; Hasenberg, Anja; Zelinskyy, Gennadiy; Westmeier, Jaana; Hasenkrug, Kim J.; Dittmer, Ulf; Gunzer, Matthias
    Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected mice
    In: JCI Insight, Jg. 8, 2023, Nr. 13, e167482
    DOI, Online Volltext (Open Access)
  • Karakoese, Zehra; Le-Trilling, Vu Thuy Khanh; Schuhenn, Jonas; Francois, Sandra; Lu, Mengji; Liu, Jia; Trilling, Mirko; Hoffmann, Daniel; Dittmer, Ulf; Sutter, Kathrin
    Targeted mutations in IFNα2 improve its antiviral activity against various viruses
    In: mBio, Jg. 14, 2023, Nr. 6, e02357-23
    DOI, Online Volltext (Open Access)

    • 2022

  • Karsten, Christina B.; Bartsch, Yannic C.; Shin, Sally A.; Slein, Matthew D.; Heller, Howard M.; Kolandaivelu, Kumaran; Middeldorp, Jaap M.; Alter, Galit; Julg, Boris
    Evolution of functional antibodies following acute Epstein-Barr virus infection
    In: PLoS Pathogens, Jg. 18, 2022, Nr. 9, e1010738
    DOI (Open Access)
  • Sperber, Hannah Sabeth; Sutter, Kathrin; Müller, Karin; Müller, Peter; Schwarzer, Roland
    The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral Activity
    In: Viruses, Jg. 14, 2022, Nr. 9, 2031
    DOI, Online Volltext (Open Access)
  • Packard, Thomas A.; Schwarzer, Roland; Herzig, Eytan; Rao, Deepashri; Luo, Xiaoyu; Egedal, Johanne H.; Hsiao, Feng; Widera, Marek; Hultquist, Judd F.; Grimmett, Zachary W.; Messer, Ronald J.; Krogan, Nevan J.; Deeks, Steven G.; Roan, Nadia R.; Dittmer, Ulf; Hasenkrug, Kim J.; Greene, Warner C.
    CCL2 : a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir
    In: mBio, Jg. 13, 2022, Nr. 5, e0189122
    DOI, Online Volltext (Open Access)
  • Streeck, Hendrik; Maestri, Alvino; Habermann, Daniel; Crowell, Trevor A.; Esber, Allahna L.; Son, Gowoon; Eller, Leigh Anne; Eller, Michael A.; Parikh, Ajay P.; Horn, Peter; Maganga, Lucas; Bahemana, Emmanuel; Adamu, Yakubu; Kiweewa, Francis; Maswai, Jonah; Owuoth, John; Robb, Merlin L.; Michael, Nelson L.; Polyak, Christina S.; Hoffmann, Daniel; Ake, Julie A.
    Dissecting drivers of immune activation in chronic HIV-1 infection
    In: eBioMedicine, Jg. 83, 2022, 104182
    DOI (Open Access)
  • Karakoese, Zehra; Schwerdtfeger, Mara; Karsten, Christina; Esser, Stefan; Dittmer, Ulf; Sutter, Kathrin
    Distinct Type I Interferon Subtypes Differentially Stimulate T Cell Responses in HIV-1-Infected Individuals
    In: Frontiers in Immunology, Jg. 13, 2022, 936918
    DOI, Online Volltext (Open Access)
  • Finch, Emilie; Lowe, Rachel; Fischinger, Stephanie; de St Aubin, Michael; Siddiqui, Sameed M.; Dayal, Diana; Loesche, Michael A.; Rhee, Justin; Beger, Samuel; Hu, Yiyuan; Gluck, Matthew J.; Mormann, Benjamin; Hasdianda, Mohammad A.; Musk, Elon R.; Alter, Galit; Menon, Anil S.; Nilles, Eric J.; Kucharski, Adam J.; Lei, Jiayao; Funk, Sebastian; Sun, Fiona Yueqian; Gimma, Amy; Nightingale, Emily S.; Medley, Graham; Abbott, Sam; Krauer, Fabienne; Davies, Nicholas G.; Jit, Mark; Endo, Akira; Brady, Oliver; Foss, Anna M.; Chan, Yung-Wai Desmond; Jombart, Thibaut; van Zandvoort, Kevin; Eggo, Rosalind M.; Liu, Yang; Knight, Gwenan M.; Pearson, Carl A.B.; Abbas, Kaja; Atkins, Katherine E.; Clifford, Samuel; Koltai, Mihaly; Jafari, Yalda; Tully, Damien C.; Jarvis, Christopher I.; O'Reilly, Kathleen; Bosse, Nikos I.; Prem, Kiesha; Quilty, Billy J.; Procter, Simon R.; Barnard, Rosanna C.; Waites, William; McCarthy, Ciara; Munday, James D.; Hodgson, David; Edmunds, W. John; Rosello, Alicia; Villabona-Arenas, C. Julian; Gibbs, Hamish P.; Flasche, Stefan; Russell, Timothy W.; Meakin, Sophie R.; Hellewell, Joel; Waterlow, Naomi R.; Quaife, Matthew; Sandmann, Frank G.
    SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohort
    In: PLoS Biology, Jg. 20, 2022, Nr. 2, e3001531
    DOI (Open Access)
  • Streeck, Hendrik; Jansen, Klaus; Crowell, Trevor A.; Esber, Allahna; Jessen, Heiko K.; Cordes, Christiane; Scholten, Stefan; Schneeweiss, Stephan; Brockmeyer, Norbert; Spinner, Christoph D.; Bickel, Markus; Esser, Stefan; Hartikainen, Jukka; Stoehr, Albrecht; Lehmann, Clara; Marcus, Ulrich; Vehreschild, Jorg Janne; Knorr, Alexandra; Brillen, Anna-Lena; Tiemann, Carsten; Robb, Merlin L.; Michael, Nelson L.
    HIV pre-exposure prophylaxis was associated with no impact on sexually transmitted infection prevalence in a high-prevalence population of predominantly men who have sex with men, Germany, 2018 to 2019
    In: Eurosurveillance, Jg. 27, 2022, Nr. 14, 2100591
    DOI (Open Access)
  • Klug, Yoel A.; Schwarzer, Roland; Ravula, Thirupathi; Rotem, Etai; Ramamoorthy, Ayyalusamy; Shai, Yechiel
    Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane Fusion
    In: Biochemistry, Jg. 61, 2022, Nr. 17, S. 1915 – 1922
    DOI, Online Volltext (Open Access)
  • Ettich, Julia; Werner, Julia; Weitz, Hendrik T.; Mueller, Eva; Schwarzer, Roland; Lang, Philipp A.; Scheller, Jürgen; Moll, Jens M.
    A Hybrid Soluble gp130/Spike-Nanobody Fusion Protein Simultaneously Blocks Interleukin-6 trans-Signaling and Cellular Infection with SARS-CoV-2
    In: Journal of Virology, Jg. 96, 2022, Nr. 4, e01622-21
    DOI (Open Access)
  • Welke, Robert-William; Sperber, Hannah Sabeth; Bergmann, Ronny; Koikkarah, Amit; Menke, Laura; Sieben, Christian; Krüger, Detlev H.; Chiantia, Salvatore; Herrmann, Andreas; Schwarzer, Roland
    Characterization of Hantavirus N Protein Intracellular Dynamics and Localization
    In: Viruses, Jg. 14, 2022, Nr. 3, 457
    DOI, Online Volltext (Open Access)
  • Adam, Lutz; Müller, Eva; Ludwig, Kai; Klenk, Simon; Lauster, Daniel; Liese, Susanne; Herrmann, Andreas; Hackenberger, Christian P. R.
    Design and Functional Analysis of Heterobifunctional Multivalent Phage Capsid Inhibitors Blocking the Entry of Influenza Virus
    In: Bioconjugate Chemistry, Jg. 33, 2022, Nr. 7, S. 1269 – 1278
    DOI (Open Access)
  • Richter, Enrico; Bornemann, Lea; Korencak, Marek; Alter, Galit; Schuster, Marc; Esser, Stefan; Boesecke, Christoph; Rockstroh, Juergen; Gunzer, Matthias; Streeck, Hendrik
    Reduction of CD8 T Cell Functionality but Not Inhibitory Capacity by Integrase Inhibitors
    In: Journal of Virology, Jg. 96, 2022, Nr. 5, e01730-21
    DOI, Online Volltext (Open Access)

    • 2021

  • Karsten, Christina
    Die HIV-Pandemie : Ein Problem weltweit, auch in Deutschland
    In: Unikate: Berichte aus Forschung und Lehre, 2021, Nr. 56 : "Junge Wilde" - Die nächste Generation, S. 40 – 49
    DOI, Online Volltext (Open Access)
  • Bartsch, Yannic C.; Fischinger, Stephanie; Siddiqui, Sameed M.; Chen, Zhilin; Yu, Jingyou; Gebre, Makda; Atyeo, Caroline; Gorman, Matthew J.; Zhu, Alex Lee; Kang, Jaewon; Burke, John S.; Slein, Matthew; Gluck, Matthew J.; Beger, Samuel; Hu, Yiyuan; Rhee, Justin; Petersen, Eric; Mormann, Benjamin; Aubin, Michael de St; Hasdianda, Mohammad A.; Jambaulikar, Guruprasad; Boyer, Edward W.; Sabeti, Pardis C.; Barouch, Dan H.; Julg, Boris D.; Musk, Elon R.; Menon, Anil S.; Lauffenburger, Douglas A.; Nilles, Eric J.; Alter, Galit
    Discrete SARS-CoV-2 antibody titers track with functional humoral stability
    In: Nature Communications, Jg. 12, 2021, Nr. 1, S. 1018
    DOI (Open Access)
  • Pušnik, Jernej; Fischinger, Stephanie; Dittmer, Ulf; Esser, Stefan; van Gils, Marit J.; Sanders, Rogier W.; Alter, Galit; Streeck, Hendrik
    Production of HIV-1 env-specific antibodies mediating innate immune functions depends on cognate interleukin-21-secreting CD4⁺T cells
    In: Journal of Virology, Jg. 95, 2021, Nr. 8, S. e02097
    DOI, Online Volltext (Open Access)

    • 2020

  • Esser, Stefan
    Denken Sie bei HIV-Infizierten auch ans Herz! : Kardiovaskuläre Erkrankungen
    In: MMW - Fortschritte der Medizin, Jg. 162, 2020, S. 20 – 23
    DOI
  • Kroon, Elouise E.; Kinnear, Craig J.; Orlova, Marianna; Fischinger, Stephanie; Shin, Sally; Boolay, Sihaam; Walzl, Gerhard; Jacobs, Ashley; Wilkinson, Robert J.; Alter, Galit; Schurr, Erwin; Hoal, Eileen G.; Möller, Marlo
    An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa
    In: eBioMedicine, Jg. 61, 2020, 103053
    DOI (Open Access)
  • Bojkova, Denisa; Westhaus, Sandra; Costa, Rui; Timmer, Lejla; Funkenberg, Nora; Korencak, Marek; Streeck, Hendrik; Vondran, Florian; Bröring, Ruth; Heinrichs, Stefan; Lang, Karl S.; Ciesek, Sandra
    Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes
    In: Cells, Jg. 9, 2020, Nr. 4, 1003
    DOI (Open Access)
  • Martin, Jacob T.; Cottrell, Christopher A.; Antanasijevic, Aleksandar; Carnathan, Diane G.; Cossette, Benjamin J.; Enemuo, Chiamaka A.; Gebru, Etse H.; Choe, Yury; Viviano, Federico; Fischinger, Stephanie; Tokatlian, Talar; Cirelli, Kimberly M.; Ueda, George; Copps, Jeffrey; Schiffner, Torben; Menis, Sergey; Alter, Galit; Schief, William R.; Crotty, Shane; King, Neil P.; Baker, David; Silvestri, Guido; Ward, Andrew B.; Irvine, Darrell J.
    Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations
    In: npj Vaccines, Jg. 5, 2020, Nr. 1, 72
    DOI (Open Access)
  • David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A.; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D.; Tenbusch, Matthias; Dietze, Kirsten; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S.; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid; Dittmer, Ulf; Zelinskyy, Gennadiy
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
    In: PLoS Pathogens, Jg. 16, 2020, Nr. 3, e1008340
    DOI (Open Access)

    • 2019

  • Korencak, Marek; Byrne, Morgan; Richter, Enrico; Schultz, Bruce T.; Juszczak, Patrick; Ake, Julie A.; Ganesan, Anuradha; Okulicz, Jason F.; Robb, Merlin L.; De Los Reyes, Buena; Winning, Sandra; Fandrey, Joachim; Burgess, Timothy H.; Esser, Stefan; Michael, Nelson L.; Agan, Brian K.; Streeck, Hendrik
    Effect of HIV infection and antiretroviral therapy on immune cellular functions
    In: JCI Insight, Jg. 4, 2019, Nr. 12, :e126675
    DOI (Open Access)
  • Fischinger, Stephanie; Fallon, Jonathan K.; Michell, Ashlin R.; Broge, Thomas; Suscovich, Todd J.; Streeck, Hendrik; Alter, Galit
    A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation
    In: Journal of Immunological Methods, Jg. 473, 2019, S. 112630
    DOI (Open Access)
  • Pušnik, Jernej; Eller, Michael A.; Tassaneetrithep, Boonrat; Schultz, Bruce T.; Eller, Leigh Anne; Nitayaphan, Sorachai; Kosgei, Josphat; Maganga, Lucas; Kibuuka, Hannah; Alter, Galit; Michael, Nelson L.; Robb, Merlin L.; Streeck, Hendrik
    Expansion of Stem Cell-Like CD4⁺ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease Progression
    In: Journal of Virology, Jg. 93, 2019, Nr. 14
    DOI, Online Volltext (Open Access)
  • Kehrmann, Jan; Menzel, Jannis; Saeedghalati, Mohammadkarim; Obeid, Rima; Schulze, Christina; Holzendorf, Volker; Farahpour, Farnoush; Reinsch, Nico; Klein-Hitpaß, Ludger; Streeck, Hendrik; Hoffmann, Daniel; Buer, Jan; Esser, Stefan
    Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease
    In: The Journal of Infectious Diseases (JID), Jg. 219, 2019, Nr. 3, S. 497 – 508
    DOI (Open Access)
  • Reinsch, Nico; Streeck, Hendrik; Holzendorf, Volker; Schulze, Christina; Neumann, Till; Brockmeyer, Norbert H.; Kehrmann, Jan; Schadendorf, Dirk; Esser, Stefan
    B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV : Results from the HIV-HEART study
    In: International Journal of Cardiology, Jg. 281, 2019, S. 127 – 132
    DOI
  • Fischinger, Stephanie; Boudreau, Carolyn M.; Butler, Audrey L.; Streeck, Hendrik; Alter, Galit
    Sex differences in vaccine-induced humoral immunity
    In: Seminars in Immunopathology, Jg. 41, 2019, Nr. 2, S. 239 – 249
    DOI (Open Access)

    • 2018

  • Teigler, Jeffrey E; Leyre, Louise; Chomont, Nicolas; Slike, Bonnie; Jian, Ningbo; Eller, Michael A; Phanuphak, Nittaya; Kroon, Eugène; Pinyakorn, Suteeraporn; Eller, Leigh Anne; Robb, Merlin L; Ananworanich, Jintanat; Michael, Nelson L; Streeck, Hendrik; Krebs, Shelly J; RV254/RV217 study groups
    Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size
    In: JCI Insight, Jg. 3, 2018, Nr. 10, e98420
    DOI (Open Access)
  • Costanzo, Margaret C.; Kim, Dohoon; Creegan, Matthew; Lal, Kerri G.; Ake, Julie A.; Currier, Jeffrey R.; Streeck, Hendrik; Robb, Merlin L.; Michael, Nelson L.; Bolton, Diane L.; Steers, Nicholas J.; Eller, Michael A.
    Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccination
    In: Nature Communications, Jg. 9, 2018, Nr. 1, S. 1212
    DOI (Open Access)
  • Lofano, Giuseppe; Gorman, Matthew J; Yousif, Ashraf S; Yu, Wen-Han; Fox, Julie M; Dugast, Anne-Sophie; Ackerman, Margaret E; Suscovich, Todd J; Weiner, Joshua; Barouch, Dan; Streeck, Hendrik; Little, Susan J.; Smith, Davey M.; Richman, Douglas; Lauffenburger, Douglas; Walker, Bruce D; Diamond, Michael S; Alter, Galit
    Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement
    In: Science Immunology, Jg. 3, 2018, Nr. 26, S. eaat7796
    DOI (Open Access)
  • Sadanand, Saheli; Das, Jishnu; Chung, Amy W.; Schoen, Matthew K.; Lane, Sophie; Suscovich, Todd J.; Streeck, Hendrik; Smith, Davey M.; Little, Susan J.; Lauffenburger, Douglas A.; Richman, Douglas D.; Alter, Galit
    Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors
    In: AIDS, Jg. 32, 2018, Nr. 4, S. 443 – 450
    DOI, Online Volltext (Open Access)
  • Yu, Wen-Han; Zhao, Peng; Draghi, Monia; Arevalo, Claudia; Karsten, Christina B.; Suscovich, Todd J; Gunn, Bronwyn; Streeck, Hendrik; Brass, Abraham L; Tiemeyer, Michael; Seaman, Michael; Mascola, John R; Wells, Lance; Lauffenburger, Douglas A; Alter, Galit
    Exploiting glycan topography for computational design of Env glycoprotein antigenicity
    In: PLoS Computational Biology, Jg. 14, 2018, Nr. 4, S. e1006093
    DOI (Open Access)
  • Buggert, Marcus; Nguyen, Son; McLane, Laura M; Steblyanko, Maria; Anikeeva, Nadia; Paquin-Proulx, Dominic; Del Rio Estrada, Perla M; Ablanedo-Terrazas, Yuria; Noyan, Kajsa; Reuter, Morgan A; Demers, Korey; Sandberg, Johan K; Eller, Michael A; Streeck, Hendrik; Jansson, Marianne; Nowak, Piotr; Sönnerborg, Anders; Canaday, David H; Naji, Ali; Wherry, E John; Robb, Merlin L; Deeks, Steven G; Reyes-Teran, Gustavo; Sykulev, Yuri; Karlsson, Annika C; Betts, Michael R
    Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
    In: PLoS Pathogens, Jg. 14, 2018, Nr. 4, S. e1006973
    DOI (Open Access)
  • Pissani, Franco; Schulte, Bianca; Eller, Michael A.; Schultz, Bruce T.; Ratto-Kim, Silvia; Marovich, Mary; Thongcharoen, Prasert; Sriplienchan, Somchai; Rerks-Ngarm, Supachai; Pitisuttithum, Punnee; Esser, Stefan; Alter, Galit; Robb, Merlin L.; Kim, Jerome H.; Michael, Nelson L.; Streeck, Hendrik
    Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in Humans
    In: Journal of Virology, Jg. 92, 2018, Nr. 23, S. e01143 – 18
    DOI, Online Volltext (Open Access)

    • 2017

  • Malyshkina, Anna; Littwitz-Salomon, Elisabeth; Sutter, Kathrin; Zelinskyy, Gennadiy; Windmann, Sonja; Schimmer, Simone; Paschen, Annette; Streeck, Hendrik; Hasenkrug, Kim J; Dittmer, Ulf
    Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection
    In: Scientific Reports, Jg. 7, 2017, S. 7785
    DOI (Open Access)
  • Esser, Stefan; Streeck, Hendrik
    Preexposure prophylaxis failure with tenofovir disoproxil
    In: AIDS, Jg. 31, 2017, Nr. 9, S. 1344
    DOI
  • Streeck, Hendrik; Verheyen, Jens; Storim, Julian; Dittmer, Ulf; Jochum, Christoph; Timm, Jörg; Esser, Stefan
    Pre-exposure prophylaxis failure with tenofovir disoproxil
    In: AIDS, Jg. 31, 2017, Nr. 1, S. 176 – 177
    DOI
  • Li, Yanpeng; Sun, Binlian; Esser, Stefan; Jessen, Heiko; Streeck, Hendrik; Widera, Marek; Yang, Rongge; Dittmer, Ulf; Sutter, Kathrin
    Expression pattern of individual IFNA subtypes in chronic HIV infection
    In: Journal of Interferon & Cytokine Research, Jg. 37, 2017, Nr. 12, S. 541 – 549
    DOI
  • Buranapraditkun, Supranee; Pissani, Franco; Teigler, Jeffrey E.; Schultz, Bruce T.; Alter, Galit; Marovich, Mary; Robb, Merlin L.; Eller, Michael A.; Martin, Jeff; Deeks, Steven; Michael, Nelson L.; Streeck, Hendrik
    Preservation of peripheral T follicular helper cell function in HIV controllers
    In: Journal of Virology, Jg. 91, 2017, Nr. 14, S. e00497 – 17
    DOI (Open Access)
  • Teigler, Jeffrey E.; Zelinskyy, Gennadiy; Eller, Michael A.; Bolton, Diane L.; Marovich, Mary; Gordon, Alexander D.; Alrubayyi, Aljawharah; Alter, Galit; Robb, Merlin L.; Martin, Jeffrey N.; Deeks, Steven G.; Michael, Nelson L.; Dittmer, Ulf; Streeck, Hendrik
    Differential inhibitory receptor expression on T cells delineates functional capacities in chronic viral infection
    In: Journal of Virology, Jg. 91, 2017, Nr. 23, S. e01263 – 17
    DOI, Online Volltext (Open Access)

    • 2016

  • Sips, M; Krykbaeva, M; Diefenbach, T J; Ghebremichael, M; Bowman, B A; Dugast, A-S; Boesch, A W; Streeck, Hendrik; Kwon, D S; Ackerman, M E; Suscovich, T J; Brouckaert, P; Schacker, T W; Alter, G
    Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies
    In: Mucosal Immunology, Jg. 9, 2016, Nr. 6, S. 1584 – 1595
    DOI, Online Volltext (Open Access)
  • Lu, Lenette L; Chung, Amy W; Rosebrock, Tracy R; Ghebremichael, Musie; Yu, Wen Han; Grace, Patricia S; Schoen, Matthew K; Tafesse, Fikadu; Martin, Constance; Leung, Vivian; Mahan, Alison E; Sips, Magdalena; Kumar, Manu P; Tedesco, Jacquelynne; Robinson, Hannah; Tkachenko, Elizabeth; Draghi, Monia; Freedberg, Katherine J; Streeck, Hendrik; Suscovich, Todd J; Lauffenburger, Douglas A; Restrepo, Blanca I; Day, Cheryl; Fortune, Sarah M; Alter, Galit
    A Functional Role for Antibodies in Tuberculosis
    In: Cell, Jg. 167, 2016, Nr. 2, S. 433 – 443.e14
    DOI (Open Access)
  • Mahan, Alison E; Jennewein, Madeleine F; Suscovich, Todd; Dionne, Kendall; Tedesco, Jacquelynne; Chung, Amy W; Streeck, Hendrik; Pau, Maria; Schuitemaker, Hanneke; Francis, Don; Fast, Patricia; Laufer, Dagna; Walker, Bruce D; Baden, Lindsey; Barouch, Dan H; Alter, Galit
    Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination
    In: PLoS Pathogens, Jg. 12, 2016, Nr. 3, S. e1005456
    DOI (Open Access)
  • Stein, J; Storcksdieck Genannt Bonsmann, M; Streeck, Hendrik
    Barriers to HIV Cure
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens), Jg. 88, 2016, Nr. 4, S. 155 – 163
    DOI
  • Gunn, B M; Schneider, J R; Shansab, M; Bastian, A R; Fahrbach, K M; Smith, A D; Mahan, A E; Karim, M M; Licht, A F; Zvonar, I; Tedesco, J; Anderson, M R; Chapel, A; Suscovich, T J; Malaspina, D C; Streeck, Hendrik; Walker, B D; Kim, A; Lauer, G; Altfeld, M; Pillai, S; Szleifer, I; Kelleher, N L; Kiser, P F; Hope, T J; Alter, G
    Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16
    In: Mucosal Immunology, Jg. 9, 2016, Nr. 6, S. 1549 – 1558
    DOI
  • Ranasinghe, Srinika; Lamothe, Pedro A; Soghoian, Damien Z; Kazer, Samuel W; Cole, Michael B; Shalek, Alex K; Yosef, Nir; Jones, R Brad; Donaghey, Faith; Nwonu, Chioma; Jani, Priya; Clayton, Gina M; Crawford, Frances; White, Janice; Montoya, Alana; Power, Karen; Allen, Todd M; Streeck, Hendrik; Kaufmann, Daniel E; Picker, Louis J; Kappler, John W; Walker, Bruce D
    Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion
    In: Immunity, Jg. 45, 2016, Nr. 4, S. 917 – 930
    DOI (Open Access)
  • Streeck, Hendrik
    Designing optimal HIV-vaccine T-cell responses
    In: Current Opinion in HIV and AIDS, Jg. 11, 2016, Nr. 6, S. 593 – 600
    DOI
  • Akhmetzyanova, Ilseyar; Dittmer, Ulf; Brandau, Sven; Streeck, Hendrik; Dietze, Kirsten; Malyshkina, Anna; Littwitz-Salomon, Elisabeth; Zelinskyy, Gennadiy
    CD137 agonist therapy can reprogram regulatory T cells into cytotoxic CD4+ T cells with antitumor activity
    In: The Journal of Immunology (JI), Jg. 196, 2016, Nr. 1, S. 484 – 492
    DOI (Open Access)
  • Leitman, Ellen M; Goulder, Philip J.R; Streeck, Hendrik; De Burgh-Thomas, Andrew; Willberg, Christian B.; Matthews, Philippa C.
    Subdominant Gag-specific anti-HIV efficacy in an HLA-B*57-positive elite controller
    In: AIDS, Jg. 30, 2016, Nr. 6, S. 972 – 974
    DOI, Online Volltext (Open Access)
  • Lewis, Gavin M; Wehrens, Ellen J; Labarta-Bajo, Lara; Streeck, Hendrik; Zuniga, Elina I
    TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections
    In: The Journal of Clinical Investigation (JCI), Jg. 126, 2016, Nr. 10, S. 3799 – 3813
    DOI

    • 2015

  • Johnson, Susan; Eller, Michael; Teigler, Jeffrey E; Maloveste, Sebastien M; Schultz, Bruce T; Soghoian, Damien Z; Lu, Richard; Oster, Alexander F; Chenine, Agnès-Laurence; Alter, Galit; Dittmer, Ulf; Marovich, Mary; Robb, Merlin L; Michael, Nelson L; Bolton, Diane; Streeck, Hendrik
    Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia
    In: Journal of Virology, Jg. 89, 2015, Nr. 15, S. 7494 – 7505
    DOI (Open Access)
  • Adoro, Stanley; Cubillos-Ruiz, Juan R; Chen, Xi; Deruaz, Maud; Vrbanac, Vladimir D; Song, Minkyung; Park, Suna; Murooka, Thomas T; Dudek, Timothy E; Luster, Andrew D; Tager, Andrew M; Streeck, Hendrik; Bowman, Brittany; Walker, Bruce D; Kwon, Douglas S; Lazarevic, Vanja; Glimcher, Laurie H
    IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection
    In: Nature Communications, Jg. 6, 2015, S. 7562
    DOI (Open Access)
  • Chung, Amy W; Kumar, Manu P; Arnold, Kelly B; Yu, Wen Han; Schoen, Matthew K; Dunphy, Laura J; Suscovich, Todd J; Frahm, Nicole; Linde, Caitlyn; Mahan, Alison E; Hoffner, Michelle; Streeck, Hendrik; Ackerman, Margaret E; McElrath, M Juliana; Schuitemaker, Hanneke; Pau, Maria G; Baden, Lindsey R; Kim, Jerome H; Michael, Nelson L; Barouch, Dan H; Lauffenburger, Douglas A; Alter, Galit
    Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology
    In: Cell, Jg. 163, 2015, Nr. 4, S. 988 – 998
    DOI (Open Access)
  • Streeck, Hendrik
    HIV-specific TFH cells induced by vaccination and natural infection
    In: Journal of Medical Primatology, Jg. 44, 2015, Nr. 5, Special Issue: 32nd Annual Symposium on Nonhuman Primate Models for AIDS, S. 321
    DOI
  • Streeck, Hendrik
    AIDS virus seeks refuge in B cell follicles
    In: Nature Medicine, Jg. 21, 2015, Nr. 2, S. 111 – 112
    DOI