Publications
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The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITAIn: eLife, Vol. 14, 2025, e96414DOI, Online Full Text (Open Access)
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Gut microbiota differences linked to weight gain and ART in people living with HIV are enterotype specific and minor compared to the large differences linked to sexual behaviorIn: Frontiers in Cellular and Infection Microbiology, Vol. 15, 2025, 1568352DOI, Online Full Text (Open Access)
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Diketopiperazine/piperidine alkaloid as a potential broad-spectrum coronaviral entry inhibitor identified by supercomputer-based virtual screening from a large natural product-based libraryIn: Biomedicine & Pharmacotherapy, Vol. 183, 2025, 117841DOI (Open Access)
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Iron improves the antiviral activity of NK cellsIn: Frontiers in Immunology, Vol. 15, 2025, 1526197DOI, Online Full Text (Open Access)
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Reactivation of latent HIV-1 by the glucocorticoid receptor modulator AZD9567In: Journal of Virology, Vol. 99, 2025, Nr. 2, e01886-24DOI (Open Access)
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Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH)In: Vaccines, Vol. 12, 2024, Nr. 7, 785DOI (Open Access)
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Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furinIn: Virus Research, Vol. 350, 2024, 199485DOI (Open Access)
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Persistent low-level viraemia is associated with non-infectious comorbidities in an observational cohort in four African countriesIn: Journal of the International AIDS Society, Vol. 27, 2024, Nr. 8, e26316DOI (Open Access)
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T Cell Responses against Orthopoxviruses in HIV-Positive PatientsIn: Vaccines, Vol. 12, 2024, Nr. 2, 131DOI (Open Access)
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Identification of nitrile-containing isoquinoline-related natural product derivatives as coronavirus entry inhibitors in silico and in vitroIn: Biomedicine & Pharmacotherapy, Vol. 180, 2024, 117517DOI (Open Access)
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An efficient ELISA protocol for measurement of SARS-CoV-2 spike-specific IgG in human plasma and serum samplesIn: MethodsX, Vol. 12, 2024, 102596DOI, Online Full Text (Open Access)
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Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterningIn: eLife, Vol. 13, 2024, e85560DOI (Open Access)
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PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected miceIn: Frontiers in Immunology, Vol. 15, 2024, 1338218DOI, Online Full Text (Open Access)
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Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivityIn: PLoS Pathogens, Vol. 20, 2024, Nr. 5, e1012190DOI (Open Access)
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IFNα Subtypes in HIV Infection and ImmunityIn: Viruses, Vol. 16, 2024, Nr. 3, 364DOI, Online Full Text (Open Access)
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Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cellsIn: Cell Reports Medicine, Vol. 5, 2024, Nr. 4, 101483DOI (Open Access)
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UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an exampleIn: BMC Genomics, Vol. 25, 2024, Nr. 1, 647DOI, Online Full Text (Open Access)
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The Association of HIV-Specific Risk Factors with Cardiovascular Events in Addition to Traditional Risk Factors in People Living with HIVIn: AIDS Research and Human Retroviruses, Vol. 40, 2024, Nr. 4, pp. 235 – 245
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Analyses of defined human cytomegalovirus-specific antibody effector functions in people living with human immunodeficiency virus
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 24, 2023, Nr. 1, pp. 48 – 49 -
Distinct type I interferon subtypes differentially stimulate T cell responses in HIV1-infected individuals
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 24, 2023, Nr. 1, pp. 92 -
Changes in body mass index, weight, and waist-to-hip ratio over five years in HIV-positive individuals in the HIV Heart Aging Study compared to the general populationIn: Infection - A Journal of Infectious Disease, Vol. 51, 2023, Nr. 4, pp. 1081 – 1091DOI (Open Access)
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Fatty acids are crucial to fuel NK cells upon acute retrovirus infectionIn: Frontiers in Immunology, Vol. 14, 2023, 1296355DOI, Online Full Text (Open Access)
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High hepatitis B vaccination coverage among a cohort of predominantly men who have sex with men in GermanyIn: Human Vaccines & Immunotherapeutics, Vol. 19, 2023, Nr. 2, 2238576DOI (Open Access)
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False-positive HIV diagnosis post SARSCoV-2 infection : a case report
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 24, 2023, Nr. Supplement 1, pp. 90 -
Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor Improves Leukocyte Energy Metabolism in Hereditary Hemorrhagic TelangiectasiaIn: Life, Vol. 13, 2023, Nr. 8, 1708DOI, Online Full Text (Open Access)
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Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell folliclesIn: PLoS Pathogens, Vol. 19, 2023, Nr. 10, e1011725DOI (Open Access)
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The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latencyIn: Cell Reports, Vol. 42, 2023, Nr. 11, 113285DOI (Open Access)
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Effects of type I interferons on HIV latency
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 24, 2023, Nr. S1, pp. 82 -
PLA stereocomplex-chitosan nanoparticles loaded with tenofovir alafenamide as a long-acting antiretroviralsIn: Advanced Powder Technology, Vol. 34, 2023, Nr. 11, 104205
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Preparing for future European efficacy trials of interventions to prevent HIV and other sexually transmitted infections : Lessons on willingness to participate and barriers to participation from ten German clinics serving behaviorally vulnerable men who have sex with menIn: Vaccine: X, Vol. 14, 2023, 100302DOI (Open Access)
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False-Positive Screening and Confirmatory HIV Diagnostic Test in a Patient with Cured SARS-CoV-2 Infection Is Not Mediated by Env/Spike Cross-Reactive AntibodiesIn: Viruses, Vol. 15, 2023, Nr. 5, 1161DOI (Open Access)
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HIV-1 gp120 polymorphisms A281T and M426R might influence the efficacy of fostemsavir in an HIV-1 LLV patient
DÖAK 2023 / German-Austrian AIDS Conference, Bonn, Germany, 23-25 March 2023,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 24, 2023, Nr. 1, pp. 14 – 15 -
Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected miceIn: JCI Insight, Vol. 8, 2023, Nr. 13, e167482DOI, Online Full Text (Open Access)
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio, Vol. 14, 2023, Nr. 6, e02357-23DOI, Online Full Text (Open Access)
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Evolution of functional antibodies following acute Epstein-Barr virus infectionIn: PLoS Pathogens, Vol. 18, 2022, Nr. 9, e1010738DOI (Open Access)
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The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral ActivityIn: Viruses, Vol. 14, 2022, Nr. 9, 2031DOI, Online Full Text (Open Access)
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CCL2 : a Chemokine Potentially Promoting Early Seeding of the Latent HIV ReservoirIn: mBio, Vol. 13, 2022, Nr. 5, e0189122DOI, Online Full Text (Open Access)
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Dissecting drivers of immune activation in chronic HIV-1 infectionIn: eBioMedicine, Vol. 83, 2022, 104182DOI (Open Access)
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Distinct Type I Interferon Subtypes Differentially Stimulate T Cell Responses in HIV-1-Infected IndividualsIn: Frontiers in Immunology, Vol. 13, 2022, 936918DOI, Online Full Text (Open Access)
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SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohortIn: PLoS Biology, Vol. 20, 2022, Nr. 2, e3001531DOI (Open Access)
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HIV pre-exposure prophylaxis was associated with no impact on sexually transmitted infection prevalence in a high-prevalence population of predominantly men who have sex with men, Germany, 2018 to 2019In: Eurosurveillance, Vol. 27, 2022, Nr. 14, 2100591DOI (Open Access)
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Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane FusionIn: Biochemistry, Vol. 61, 2022, Nr. 17, pp. 1915 – 1922DOI, Online Full Text (Open Access)
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A Hybrid Soluble gp130/Spike-Nanobody Fusion Protein Simultaneously Blocks Interleukin-6 trans-Signaling and Cellular Infection with SARS-CoV-2In: Journal of Virology, Vol. 96, 2022, Nr. 4, e01622-21DOI (Open Access)
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Characterization of Hantavirus N Protein Intracellular Dynamics and LocalizationIn: Viruses, Vol. 14, 2022, Nr. 3, 457DOI, Online Full Text (Open Access)
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Design and Functional Analysis of Heterobifunctional Multivalent Phage Capsid Inhibitors Blocking the Entry of Influenza VirusIn: Bioconjugate Chemistry, Vol. 33, 2022, Nr. 7, pp. 1269 – 1278DOI (Open Access)
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Reduction of CD8 T Cell Functionality but Not Inhibitory Capacity by Integrase InhibitorsIn: Journal of Virology, Vol. 96, 2022, Nr. 5, e01730-21DOI, Online Full Text (Open Access)
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Die HIV-Pandemie : Ein Problem weltweit, auch in DeutschlandIn: Unikate: Berichte aus Forschung und Lehre, 2021, Nr. 56 : "Junge Wilde" - Die nächste Generation, pp. 40 – 49DOI, Online Full Text (Open Access)
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Discrete SARS-CoV-2 antibody titers track with functional humoral stabilityIn: Nature Communications, Vol. 12, 2021, Nr. 1, pp. 1018DOI (Open Access)
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Preparing for future European HIV prevention efficacy trials : lessons on willingness to participate and barriers to participation from ten German clinics serving behaviorally vulnerable men who have sex with men
18th European AIDS Conference (EACS 2021), Online & London, United Kingdom, October 27-30, 2021,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 22, 2021, Nr. S3, pp. 244 – 245 -
No difference in changes of the body mass index categories over 5 years in people living with HIV and the general population from the German Ruhr-area
18th European AIDS Conference (EACS 2021), Online & London, United Kingdom, October 27-30, 2021,In: HIV Medicine. Hoboken: Wiley-Blackwell, Vol. 22, 2021, Nr. S3, pp. 140 -
Production of HIV-1 env-specific antibodies mediating innate immune functions depends on cognate interleukin-21-secreting CD4⁺T cellsIn: Journal of Virology, Vol. 95, 2021, Nr. 8, pp. e02097DOI, Online Full Text (Open Access)
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Denken Sie bei HIV-Infizierten auch ans Herz! : Kardiovaskuläre ErkrankungenIn: MMW - Fortschritte der Medizin, Vol. 162, 2020, pp. 20 – 23
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An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South AfricaIn: eBioMedicine, Vol. 61, 2020, 103053DOI (Open Access)
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Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological ProcessesIn: Cells, Vol. 9, 2020, Nr. 4, 1003DOI (Open Access)
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Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulationsIn: npj Vaccines, Vol. 5, 2020, Nr. 1, 72DOI (Open Access)
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Immunometabolism in chronic HIV-1 infectionDuisburg, Essen, 2020DOI, Online Full Text (Open Access)
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens, Vol. 16, 2020, Nr. 3, e1008340DOI (Open Access)
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Effect of HIV infection and antiretroviral therapy on immune cellular functionsIn: JCI Insight, Vol. 4, 2019, Nr. 12, :e126675DOI (Open Access)
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A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activationIn: Journal of Immunological Methods, Vol. 473, 2019, pp. 112630DOI (Open Access)
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Expansion of Stem Cell-Like CD4⁺ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease ProgressionIn: Journal of Virology, Vol. 93, 2019, Nr. 14DOI, Online Full Text (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID), Vol. 219, 2019, Nr. 3, pp. 497 – 508DOI (Open Access)
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B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV : Results from the HIV-HEART studyIn: International Journal of Cardiology, Vol. 281, 2019, pp. 127 – 132
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Sex differences in vaccine-induced humoral immunityIn: Seminars in Immunopathology, Vol. 41, 2019, Nr. 2, pp. 239 – 249DOI (Open Access)
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Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir sizeIn: JCI Insight, Vol. 3, 2018, Nr. 10, e98420DOI (Open Access)
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Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccinationIn: Nature Communications, Vol. 9, 2018, Nr. 1, pp. 1212DOI (Open Access)
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Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complementIn: Science Immunology, Vol. 3, 2018, Nr. 26, pp. eaat7796DOI (Open Access)
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Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressorsIn: AIDS, Vol. 32, 2018, Nr. 4, pp. 443 – 450DOI, Online Full Text (Open Access)
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Exploiting glycan topography for computational design of Env glycoprotein antigenicityIn: PLoS Computational Biology, Vol. 14, 2018, Nr. 4, pp. e1006093DOI (Open Access)
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Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.In: PLoS Pathogens, Vol. 14, 2018, Nr. 4, pp. e1006973DOI (Open Access)
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Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in HumansIn: Journal of Virology, Vol. 92, 2018, Nr. 23, pp. e01143 – 18DOI, Online Full Text (Open Access)
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Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infectionIn: Scientific Reports, Vol. 7, 2017, pp. 7785DOI (Open Access)
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Preexposure prophylaxis failure with tenofovir disoproxilIn: AIDS, Vol. 31, 2017, Nr. 9, pp. 1344
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Pre-exposure prophylaxis failure with tenofovir disoproxilIn: AIDS, Vol. 31, 2017, Nr. 1, pp. 176 – 177
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Expression pattern of individual IFNA subtypes in chronic HIV infectionIn: Journal of Interferon & Cytokine Research, Vol. 37, 2017, Nr. 12, pp. 541 – 549
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Preservation of peripheral T follicular helper cell function in HIV controllersIn: Journal of Virology, Vol. 91, 2017, Nr. 14, pp. e00497 – 17DOI (Open Access)
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Differential inhibitory receptor expression on T cells delineates functional capacities in chronic viral infectionIn: Journal of Virology, Vol. 91, 2017, Nr. 23, pp. e01263 – 17DOI, Online Full Text (Open Access)
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Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategiesIn: Mucosal Immunology, Vol. 9, 2016, Nr. 6, pp. 1584 – 1595DOI, Online Full Text (Open Access)
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A Functional Role for Antibodies in TuberculosisIn: Cell, Vol. 167, 2016, Nr. 2, pp. 433 – 443.e14DOI (Open Access)
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Antigen-Specific Antibody Glycosylation Is Regulated via VaccinationIn: PLoS Pathogens, Vol. 12, 2016, Nr. 3, pp. e1005456DOI (Open Access)
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Barriers to HIV CureIn: HLA: Immune Response Genetics (Human Leukocyte Antigens), Vol. 88, 2016, Nr. 4, pp. 155 – 163
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Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16In: Mucosal Immunology, Vol. 9, 2016, Nr. 6, pp. 1549 – 1558
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Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal ExpansionIn: Immunity, Vol. 45, 2016, Nr. 4, pp. 917 – 930DOI (Open Access)
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Designing optimal HIV-vaccine T-cell responsesIn: Current Opinion in HIV and AIDS, Vol. 11, 2016, Nr. 6, pp. 593 – 600
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CD137 agonist therapy can reprogram regulatory T cells into cytotoxic CD4+ T cells with antitumor activityIn: The Journal of Immunology (JI), Vol. 196, 2016, Nr. 1, pp. 484 – 492DOI (Open Access)
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Subdominant Gag-specific anti-HIV efficacy in an HLA-B*57-positive elite controllerIn: AIDS, Vol. 30, 2016, Nr. 6, pp. 972 – 974DOI, Online Full Text (Open Access)
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TGF-β receptor maintains CD4 T helper cell identity during chronic viral infectionsIn: The Journal of Clinical Investigation (JCI), Vol. 126, 2016, Nr. 10, pp. 3799 – 3813
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Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV ViremiaIn: Journal of Virology, Vol. 89, 2015, Nr. 15, pp. 7494 – 7505DOI (Open Access)
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IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infectionIn: Nature Communications, Vol. 6, 2015, pp. 7562DOI (Open Access)
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Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems SerologyIn: Cell, Vol. 163, 2015, Nr. 4, pp. 988 – 998DOI (Open Access)
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HIV-specific TFH cells induced by vaccination and natural infectionIn: Journal of Medical Primatology, Vol. 44, 2015, Nr. 5, Special Issue: 32nd Annual Symposium on Nonhuman Primate Models for AIDS, pp. 321
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AIDS virus seeks refuge in B cell folliclesIn: Nature Medicine, Vol. 21, 2015, Nr. 2, pp. 111 – 112